CN105900994A - Sterilization composition containing carabrone and prothioconazole - Google Patents
Sterilization composition containing carabrone and prothioconazole Download PDFInfo
- Publication number
- CN105900994A CN105900994A CN201610337194.3A CN201610337194A CN105900994A CN 105900994 A CN105900994 A CN 105900994A CN 201610337194 A CN201610337194 A CN 201610337194A CN 105900994 A CN105900994 A CN 105900994A
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- CN
- China
- Prior art keywords
- carabrone
- bactericidal composition
- prothioconazoles
- prothioconazole
- sterilization composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000000203 mixture Substances 0.000 title claims abstract description 37
- AGIQIKMGJVLKMA-NLRWUALESA-N (3ar,4as,5s,5ar,6ar)-5a-methyl-3-methylidene-5-(3-oxobutyl)-3a,4,4a,5,6,6a-hexahydrocyclopropa[f][1]benzofuran-2-one Chemical compound C1[C@@H]2C(=C)C(=O)O[C@@H]2C[C@]2(C)[C@@H](CCC(=O)C)[C@@H]21 AGIQIKMGJVLKMA-NLRWUALESA-N 0.000 title claims abstract description 31
- AGIQIKMGJVLKMA-UHFFFAOYSA-N carabrone Natural products C1C2C(=C)C(=O)OC2CC2(C)C(CCC(=O)C)C21 AGIQIKMGJVLKMA-UHFFFAOYSA-N 0.000 title claims abstract description 31
- 230000001954 sterilising effect Effects 0.000 title abstract description 6
- 238000004659 sterilization and disinfection Methods 0.000 title abstract description 6
- MNHVNIJQQRJYDH-UHFFFAOYSA-N 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1,2-dihydro-1,2,4-triazole-3-thione Chemical compound N1=CNC(=S)N1CC(C1(Cl)CC1)(O)CC1=CC=CC=C1Cl MNHVNIJQQRJYDH-UHFFFAOYSA-N 0.000 title abstract description 5
- 239000005825 Prothioconazole Substances 0.000 title abstract description 5
- 241000221785 Erysiphales Species 0.000 claims abstract description 13
- 241000196324 Embryophyta Species 0.000 claims abstract description 12
- 241000182534 Pericallis hybrida Species 0.000 claims abstract description 11
- 208000031888 Mycoses Diseases 0.000 claims abstract description 10
- 241000209140 Triticum Species 0.000 claims abstract description 7
- 235000021307 Triticum Nutrition 0.000 claims abstract description 7
- 235000007688 Lycopersicon esculentum Nutrition 0.000 claims abstract description 6
- 240000003768 Solanum lycopersicum Species 0.000 claims abstract description 6
- 206010039509 Scab Diseases 0.000 claims abstract description 5
- 241000233679 Peronosporaceae Species 0.000 claims abstract description 3
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- 230000000844 anti-bacterial effect Effects 0.000 claims description 24
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 19
- 239000003795 chemical substances by application Substances 0.000 claims description 14
- 238000002360 preparation method Methods 0.000 claims description 12
- 239000004562 water dispersible granule Substances 0.000 claims description 8
- 239000004563 wettable powder Substances 0.000 claims description 8
- 239000007900 aqueous suspension Substances 0.000 claims description 7
- 239000012752 auxiliary agent Substances 0.000 claims description 6
- 239000000575 pesticide Substances 0.000 claims description 5
- 239000002552 dosage form Substances 0.000 claims description 4
- 235000006008 Brassica napus var napus Nutrition 0.000 claims description 2
- 240000000385 Brassica napus var. napus Species 0.000 claims 1
- 239000003814 drug Substances 0.000 abstract description 9
- 230000000694 effects Effects 0.000 abstract description 9
- 230000002045 lasting effect Effects 0.000 abstract description 5
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- 244000078912 Trichosanthes cucumerina Species 0.000 abstract 1
- 235000008322 Trichosanthes cucumerina Nutrition 0.000 abstract 1
- 241000228452 Venturia inaequalis Species 0.000 abstract 1
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- 235000012333 Vitis X labruscana Nutrition 0.000 abstract 1
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- 229940079593 drug Drugs 0.000 abstract 1
- 230000002035 prolonged effect Effects 0.000 abstract 1
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 12
- 239000000080 wetting agent Substances 0.000 description 9
- 239000008367 deionised water Substances 0.000 description 8
- 229910021641 deionized water Inorganic materials 0.000 description 8
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- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
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- 238000002474 experimental method Methods 0.000 description 4
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- 230000003449 preventive effect Effects 0.000 description 4
- -1 sesquiterpene lactones compounds Chemical class 0.000 description 4
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- 239000002245 particle Substances 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 239000000375 suspending agent Substances 0.000 description 3
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- 244000060924 Brassica campestris Species 0.000 description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
- 230000002528 anti-freeze Effects 0.000 description 2
- 238000000498 ball milling Methods 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 239000000440 bentonite Substances 0.000 description 2
- 229910000278 bentonite Inorganic materials 0.000 description 2
- SVPXDRXYRYOSEX-UHFFFAOYSA-N bentoquatam Chemical compound O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 description 2
- 239000000306 component Substances 0.000 description 2
- GHVNFZFCNZKVNT-UHFFFAOYSA-N decanoic acid Chemical compound CCCCCCCCCC(O)=O GHVNFZFCNZKVNT-UHFFFAOYSA-N 0.000 description 2
- 230000000857 drug effect Effects 0.000 description 2
- 239000000839 emulsion Substances 0.000 description 2
- 239000000417 fungicide Substances 0.000 description 2
- 239000003094 microcapsule Substances 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- 238000010008 shearing Methods 0.000 description 2
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 2
- JHJUUEHSAZXEEO-UHFFFAOYSA-M sodium;4-dodecylbenzenesulfonate Chemical compound [Na+].CCCCCCCCCCCCC1=CC=C(S([O-])(=O)=O)C=C1 JHJUUEHSAZXEEO-UHFFFAOYSA-M 0.000 description 2
- 238000001228 spectrum Methods 0.000 description 2
- 230000001629 suppression Effects 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 235000010493 xanthan gum Nutrition 0.000 description 2
- 239000000230 xanthan gum Substances 0.000 description 2
- 229920001285 xanthan gum Polymers 0.000 description 2
- 229940082509 xanthan gum Drugs 0.000 description 2
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 description 1
- 239000005995 Aluminium silicate Substances 0.000 description 1
- 235000005637 Brassica campestris Nutrition 0.000 description 1
- 239000005632 Capric acid (CAS 334-48-5) Substances 0.000 description 1
- 235000008495 Chrysanthemum leucanthemum Nutrition 0.000 description 1
- 244000192528 Chrysanthemum parthenium Species 0.000 description 1
- 235000000604 Chrysanthemum parthenium Nutrition 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 241000191398 Kalanchoe blossfeldiana Species 0.000 description 1
- 208000005767 Megalencephaly Diseases 0.000 description 1
- 240000005001 Paeonia suffruticosa Species 0.000 description 1
- 235000003889 Paeonia suffruticosa Nutrition 0.000 description 1
- 206010034133 Pathogen resistance Diseases 0.000 description 1
- 241000233616 Phytophthora capsici Species 0.000 description 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 241000567197 Puccinia graminis f. sp. tritici Species 0.000 description 1
- 241001123583 Puccinia striiformis Species 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
- 239000004141 Sodium laurylsulphate Substances 0.000 description 1
- 229930182558 Sterol Natural products 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
- 244000269722 Thea sinensis Species 0.000 description 1
- 235000006468 Thea sinensis Nutrition 0.000 description 1
- 235000010489 acacia gum Nutrition 0.000 description 1
- 239000001785 acacia senegal l. willd gum Substances 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 238000012271 agricultural production Methods 0.000 description 1
- 235000012211 aluminium silicate Nutrition 0.000 description 1
- 229960000892 attapulgite Drugs 0.000 description 1
- 239000003899 bactericide agent Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 235000015895 biscuits Nutrition 0.000 description 1
- 229920005551 calcium lignosulfonate Polymers 0.000 description 1
- RYAGRZNBULDMBW-UHFFFAOYSA-L calcium;3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate Chemical compound [Ca+2].COC1=CC=CC(CC(CS([O-])(=O)=O)OC=2C(=CC(CCCS([O-])(=O)=O)=CC=2)OC)=C1O RYAGRZNBULDMBW-UHFFFAOYSA-L 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 235000013877 carbamide Nutrition 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000000460 chlorine Substances 0.000 description 1
- 229910052801 chlorine Inorganic materials 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000006184 cosolvent Substances 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 230000017858 demethylation Effects 0.000 description 1
- 238000010520 demethylation reaction Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- YDEXUEFDPVHGHE-GGMCWBHBSA-L disodium;(2r)-3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate Chemical compound [Na+].[Na+].COC1=CC=CC(C[C@H](CS([O-])(=O)=O)OC=2C(=CC(CCCS([O-])(=O)=O)=CC=2)OC)=C1O YDEXUEFDPVHGHE-GGMCWBHBSA-L 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 235000008384 feverfew Nutrition 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 244000053095 fungal pathogen Species 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 238000011081 inoculation Methods 0.000 description 1
- 230000000749 insecticidal effect Effects 0.000 description 1
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 1
- 235000021374 legumes Nutrition 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 231100000053 low toxicity Toxicity 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000010534 mechanism of action Effects 0.000 description 1
- 239000004530 micro-emulsion Substances 0.000 description 1
- 230000003641 microbiacidal effect Effects 0.000 description 1
- 229940124561 microbicide Drugs 0.000 description 1
- 239000002855 microbicide agent Substances 0.000 description 1
- 125000006353 oxyethylene group Chemical group 0.000 description 1
- 229910052625 palygorskite Inorganic materials 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 239000000447 pesticide residue Substances 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 244000144977 poultry Species 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 238000003672 processing method Methods 0.000 description 1
- 230000004224 protection Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 210000000582 semen Anatomy 0.000 description 1
- 229930009674 sesquiterpene lactone Natural products 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 235000010413 sodium alginate Nutrition 0.000 description 1
- 239000000661 sodium alginate Substances 0.000 description 1
- 229940005550 sodium alginate Drugs 0.000 description 1
- PYODKQIVQIVELM-UHFFFAOYSA-M sodium;2,3-bis(2-methylpropyl)naphthalene-1-sulfonate Chemical compound [Na+].C1=CC=C2C(S([O-])(=O)=O)=C(CC(C)C)C(CC(C)C)=CC2=C1 PYODKQIVQIVELM-UHFFFAOYSA-M 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 150000003432 sterols Chemical class 0.000 description 1
- 235000003702 sterols Nutrition 0.000 description 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
- A01N43/647—Triazoles; Hydrogenated triazoles
- A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
- A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
- A01N43/06—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings
- A01N43/08—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings with oxygen as the ring hetero atom
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a sterilization composition containing carabrone and prothioconazole. The sterilization composition takes carabrone and prothioconazole as main effective components, wherein the mass ratio of carabrone to prothioconazole ranges from (1:80) to (80:1). The sterilization composition can be applied to prevention and treatment of common plant fungal diseases, has good prevention effect on wheat scab, corn northern leaf blight, tomato gray mold and the like and particularly can be used for preparing a drug for preventing and treating rape sclerotinia rot, bitter gourd venturia inaequalis, wheat powdery mildew, grape downy mildew, tomato gray mold, pericallis hybrida powdery mildew and the like; the acting effect is remarkably higher than that of single utilization of active components; and the drug resistance of bacteria is postponed, a lasting period is prolonged and the sterilization composition is safe to mammals.
Description
Technical field
The invention belongs to agriculture chemicals fungicide field, be specifically related to a kind of containing Carabrone and the bactericidal composition of prothioconazoles and the application in preventing and treating plant fungal disease.
Background technology
Carabrone (carabrone), it it is a kind of sesquiterpene lactones compounds, can extract from the root of feverfew Herba Carpesii macrocephali and stem and leaf and obtain, early-stage Study show its have eliminate the phlegm, heat clearing away, stop blooding, the medical active such as removing toxic substances, the most also there is bactericidal and insecticidal activity, the frequently seen plants disease such as wheat powdery mildew, take-all is had preferable preventive and therapeutic effect.
Prothioconazoles (prothioconazole), chemical name: 2-[2-(1-chlorine cyclopropyl)-3-(2-chlorphenyl)-2-hydroxypropyl]-1, 2-dihydro-3H-1, 2, 4-triazole-3-thioketone, it it is a kind of novel spectrum triazolinthione series bactericidal agent, its mechanism of action is to play bactericidal action by suppressing the demethylation effect of sterol precursor in fungus, this antibacterial has good systemic activity, protection and therapeutic effect, lasting period is long, to crop safety, it is mainly used in preventing and treating the multiple diseases on cereal crop and legume crop, Brassica campestris L and the soil-borne disease of Semen arachidis hypogaeae and common leaf diseases can also be prevented and treated.
Carabrone belongs to botanical pesticide, although has low toxicity, environmentally safe, the advantage of lasting period length, but also has the shortcoming slow, on the high side that takes effect simultaneously；Prothioconazoles is the powerful mean of current controlling plant diseases, but also faces the problems such as the generation of pathogen resistance, the drug effect reduction that single medicament life-time service causes.
Summary of the invention
For solving the problems referred to above, the present invention proposes a kind of bactericidal composition, and its main active is Carabrone and prothioconazoles, has the advantage that fungicidal spectrum is wide, low cost, preventive effect are better than single-activity composition.
The invention allows for the application in frequently seen plants fungal disease is prevented and treated of the described bactericidal composition.
The present invention is achieved through the following technical solutions:
A kind of containing Carabrone with the bactericidal composition of prothioconazoles, the weight ratio of active component Carabrone and prothioconazoles is 1:80-80:1, preferably the weight ratio of Carabrone and prothioconazoles be the weight ratio of 1:40-40:1, more preferably Carabrone and prothioconazoles be 1:8-1:1.
Bactericidal composition containing Carabrone and prothioconazoles of the present invention can be used in the preventing and treating of frequently seen plants fungal disease, such as fruit tree, vegetable, cereal crops, the industrial crops such as Cotton Gossypii, Camellia sinensis, the fungal disease on the ornamental plant such as cineraria, Paeonia suffruticosa, Kalanchoe blossfeldiana.
Described plant fungal disease includes cineraria powdery mildew, wheat scab, the leaf blight of corn, Herba Menthae spot blight, ring rot of apple, Fructus Lycopersici esculenti shot hole, graw mold of tomato, stripe rust of wheat, the stem rust of wheat, Phytophthora capsici disease etc., is preferred for preventing and treating sclerotinia rot of colza, Fructus Momordicae charantiae scab, wheat powdery mildew, downy mildew of garpe, graw mold of tomato, cineraria powdery mildew etc.
Bactericidal composition containing Carabrone and prothioconazoles of the present invention can be configured to corresponding dosage form together with the auxiliary agent adapted, in dosage form, the weight percentage of active component is usually the 1%-95% of gross weight, preferably 5%-80%, according to different type of preparation, the weight percentage of active component the most difference, in liquid preparation, active component weight percentage is usually 1%-70%, preferably 5-50%；In solid preparation, active component weight percentage is usually 2%-80%, is preferably 10%-80%.
Assistant types selected by bactericidal composition of the present invention is known in those skilled in the art, according to the required kind difference preparing preparation, one or more in the common assistant types such as dispersant, wetting agent, emulsifying agent, antifreezing agent, binding agent, defoamer, preservative, coloring agent, solvent, carrier can be selected, the selection of concrete auxiliary agent kind needs to use environment etc. to carry out screening by normal experiment according to active component content, medicament and determines, the processing method that its compound method is known to those skilled in the art.
Bactericidal composition of the present invention can be prepared as any formulations of pesticide as required: wettable powder, suspending agent, suspension emulsion, soluble powder, soluble granula, water preparation, aqueous emulsion, water dispersible granules, microcapsule suspending agent, microcapsule-microcapsule suspending agent, microemulsion, cream etc., it is also preferred that the left can be prepared as water preparation, aqueous suspension agent, wettable powder or water dispersible granules.
When described compositions is prepared as water preparation, each constituent content is: active component 1%-90%, cosolvent 1%-8%, wetting agent 1%-10%, antifreezing agent 0%-6%, and deionized water supplies surplus.
Described bactericidal composition is when being prepared as aqueous suspension agent, and each constituent content is: active component 2%-80%, dispersant 2%-12%, wetting agent 2%-10%, defoamer 0%-5%, thickening agent 0%-2%, antifreezing agent 0%-10%, and deionized water supplies 100%.
When described microbicide compositions is prepared as wettable powder, each constituent content is: active component 5%-80%, dispersant 2%-15%, wetting agent 2%-10%, filler surplus.
When described compositions is prepared as water dispersible granules, each constituent content is: active component 5%-80%, dispersant 1%-12%, wetting agent 1%-10%, disintegrating agent 1%-15%, binding agent 0.5%-9%, and surplus is filler.
Bactericidal composition containing Carabrone and prothioconazoles of the present invention can obtain following beneficial effect:
(1), plant source fungicide active ingredient Carabrones different for sterilization mechanism is compounded with prothioconazoles, frequently seen plants fungal disease can be obtained obvious synergistic function, and the lasting period extends, and also has better effects for having had drug-fast pathogen；(2) decrease chemical pesticide dosage, improve the inferior position that botanical pesticide takes effect slowly, drug effect is unstable, reduce pesticide residues, alleviate environmental pollution；(3) to person poultry safety, environmentally friendly.
Detailed description of the invention
By following example, the present invention is described in detail, but present invention is not limited in set forth below, and former medicine involved in embodiment, auxiliary agent etc. are commercially available material.
Embodiment 1 water preparation
Raw material forms: Carabrone 25%, prothioconazoles 25%, ethanol 15%, dodecylbenzene sodium sulfonate 12.5%, ethylene glycol 4.5%, and deionized water supplies surplus, is dissolved in the water by the composition such as active component, auxiliary agent so that it is dissolves fully, can be prepared by described water preparation.
Embodiment 2 water preparation
Raw material forms: Carabrone 15%, prothioconazoles 30%, ethanol 10.5%, NPE 12%, ethylene glycol 5%, and deionized water supplies surplus, is dissolved in the water by the composition such as active component, auxiliary agent so that it is dissolves fully, can be prepared by described water preparation.
Embodiment 3 aqueous suspension agent
Raw material forms: Carabrone 4%, prothioconazoles 16%, calcium lignosulfonate 12%, Nekal BX 6.5%, organic silicon defoamer 0.5%, arabic gum 1.5%, ethylene glycol 1.5%, deionized water supplies surplus, dispersant, wetting agent, defoamer, thickening agent, antifreeze are put into high-speed shearing machine and be sufficiently mixed, adds active component laggard ball mill ball milling 2-3 hour, make grain diameter meet necessary requirement, add deionized water and supply 100%, i.e. prepare described aqueous suspension agent.
Embodiment 4 aqueous suspension agent
Raw material forms: Carabrone 4%, prothioconazoles 24%, NPE 16%, dodecylbenzene sodium sulfonate 8.5%, capric acid 2%, xanthan gum 1.5%, ethylene glycol 1%, deionized water supplies surplus, dispersant, wetting agent, defoamer, thickening agent, antifreeze are put into high-speed shearing machine and be sufficiently mixed, adds active component laggard ball mill ball milling 2-3 hour, make particle diameter meet necessary requirement, add deionized water and supply 100%, i.e. prepare described aqueous suspension agent.
Embodiment 5 wettable powder
Raw material forms: Carabrone 4%, prothioconazoles 32%, octylphenol polyethylene oxyethylene group ether sulfate 15%, spaonin powder 10.5%, bentonite supplies surplus, is pulverized by laggard for all components mix homogeneously jet mill, make grain diameter meet necessary requirement, i.e. prepare described wettable powder.
Embodiment 6 wettable powder
Raw material forms: Carabrone 30%, prothioconazoles 15%, alkylphenol polyoxyethylene 16.5%, sodium laurylsulfate 8.5%, attapulgite supplies surplus, is pulverized by laggard for all components mix homogeneously jet mill, make grain diameter meet necessary requirement, i.e. prepare described wettable powder.
Embodiment 7 water dispersible granules
Raw material forms: Carabrone 40%, prothioconazoles 10%, alkylnaphthalene sulfonate 12.5%, sodium lauryl sulphate 8.5%, carbamide 1.5%, sodium alginate 3%, Kaolin supplies surplus, active component, dispersant, wetting agent, disintegrating agent is sent into together with filler jet mill and is crushed to required particle diameter, add other auxiliary components such as binding agent, carry out pelletize after mix homogeneously, the most i.e. can get described water dispersible granules product.
Embodiment 8 water dispersible granules
Raw material forms: Carabrone 40%, prothioconazoles 5%, sodium lignin sulfonate 12%, spaonin powder 12%, bentonite 5%, xanthan gum 2.5%, kieselguhr supplies surplus, active component, dispersant, wetting agent, disintegrating agent is sent into together with filler jet mill and is crushed to required particle diameter, add other auxiliary components such as binding agent, carry out pelletize after mix homogeneously, the most i.e. can get described water dispersible granules product.
The experimental example 1 suppression situation to cineraria Powdery Mildew mycelial growth
Experimental technique: measure each embodiment medicament inhibitory action to cineraria Powdery Mildew mycelial growth by using growth rate method, the medicament active constituent content each process being used through dilution operation is identical, reagent agent is added in the PDA culture medium being cooled to 40 DEG C ~ about 50 DEG C, it is sufficiently mixed, being paved into content in culture dish is 10% band poison flat board, often process 3 repetitions, the pathogenic fungi pure culture biscuits involvng inoculation of a diameter of 4mm is hit exactly in flat board.22 DEG C, cultivate under dark condition, measure each colony diameter, calculate suppression ratio according to the following equation, using sterilized water as blank under the same terms, compare as medicament using Carabrone and prothioconazoles single dose, experimental result is as shown in table 1.
Table 1 respectively processes the inhibition to cineraria Powdery Mildew mycelial growth
The experimental example 2 field control effectiveness test to cineraria powdery mildew
Experiment processes: the cineraria planting area that growth selection situation is suitable, random division is several homalographic communities, it is a process according to the medicament prepared by each embodiment, each process is in triplicate, comparison medicament is Carabrone and prothioconazoles single dose, within 5 days, 10 days, 15 days after dispenser, checking respectively for prevention effect, result of the test is shown in Table 2.
The table 2 field test results to cineraria powdery mildew
Be can be seen that by above experimental example result, bactericidal composition prevention effect of the present invention is excellent, the lasting period is long, compared with being used alone with single component, preventive effect dramatically increases, experiment proves that, bactericidal composition of the present invention all has good preventive effect to other common crop fungal diseases such as wheat scab, the leaf blight of corn, graw mold of tomato etc., has using value in agricultural production.
Claims (8)
1. a bactericidal composition, it is characterised in that with Carabrone and prothioconazoles as principle active component.
Bactericidal composition the most according to claim 1, it is characterised in that: the weight ratio of Carabrone and prothioconazoles is 1:80-80:1.
Bactericidal composition the most according to claim 2, it is characterised in that: the weight ratio of Carabrone and prothioconazoles is 1:40-40:1.
Bactericidal composition the most according to claim 3, it is characterised in that: the weight ratio of Carabrone and prothioconazoles is 1:8-1:1.
5. according to the bactericidal composition according to any one of claim 1-4, it is characterised in that: described bactericidal composition and the auxiliary agent adapted are configured on pesticide any one dosage form allowed.
Bactericidal composition the most according to claim 5, it is characterised in that described dosage form is water preparation, aqueous suspension agent, wettable powder, water dispersible granules.
Bactericidal composition the most according to claim 6, it is for preventing and treating the purposes of plant fungal disease.
Purposes the most according to claim 7, it is characterised in that described plant fungal disease is sclerotinia rot of colza, Fructus Momordicae charantiae scab, wheat powdery mildew, downy mildew of garpe, graw mold of tomato, cineraria powdery mildew etc..
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106538566A (en) * | 2016-10-31 | 2017-03-29 | 广西壮族自治区农业科学院园艺研究所 | A kind of bactericidal composition of preventing and treating fruit tree Sooty mould |
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| CN103788037A (en) * | 2012-11-02 | 2014-05-14 | 西北农林科技大学 | Method for purifying carabrone |
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| CN105230631A (en) * | 2015-09-30 | 2016-01-13 | 江苏农林职业技术学院 | Bio-origin compounded bactericidal composition for treating powdery mildew of ornamental flowers and applications thereof |
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| CN103788037A (en) * | 2012-11-02 | 2014-05-14 | 西北农林科技大学 | Method for purifying carabrone |
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| CN106538566A (en) * | 2016-10-31 | 2017-03-29 | 广西壮族自治区农业科学院园艺研究所 | A kind of bactericidal composition of preventing and treating fruit tree Sooty mould |
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