CN105891318A - Matrix-assisted laser desorption ion source sampling device - Google Patents
Matrix-assisted laser desorption ion source sampling device Download PDFInfo
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- CN105891318A CN105891318A CN201610405700.8A CN201610405700A CN105891318A CN 105891318 A CN105891318 A CN 105891318A CN 201610405700 A CN201610405700 A CN 201610405700A CN 105891318 A CN105891318 A CN 105891318A
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- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
- G01N27/626—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode using heat to ionise a gas
- G01N27/628—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode using heat to ionise a gas and a beam of energy, e.g. laser enhanced ionisation
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Abstract
The invention discloses a matrix-assisted laser desorption ion source sampling device. The device comprises a hollow part of which the interior is provided with a chamber, a Y-direction platform installed in the hollow part, an X-direction platform installed on the Y-direction platform, a target tank placed on a target tank platform installed on the X-direction platform, a target jacking mechanism and a target lifting mechanism which are installed in the hollow part and are opposite to the X-direction platform in the forward direction and a cover plate which is installed at the top of the hollow part and provided with a groove. According to the device, the groove formed in the cover plate and the target tank platform form a closed chamber through motion of the target lifting mechanism and the target jacking mechanism, the closed chamber is vacuumized by a vacuum system to form a transition vacuum chamber, therefore, the dynamic adaptive process of a sample to the vacuum degree can be effectively achieved, and operation is more flexible and convenient.
Description
Technical field
Type of the present invention relates to Matrix Assisted Laser Desorption (MALDI) technology of ion source field, particularly relates to a kind of Matrix Assisted Laser Desorption ion source sampling device.
Background technology
In the solid sample resolving that Matrix Assisted Laser Desorption ion source is carried out, sample forms solid at ambient pressure, through sampling system, vacuum system is entered by normal pressure, and need to be accurately positioned, resolve in a small region realizing sample, in extremely short time interval, laser provides high energy to sample, the heating that they are exceedingly fast, so can avoid heat sensitive compound heat resolve, substrate molecule can effectively absorb the energy of laser, and indirectly pass to sample molecule, thus ionized, also it is achieved that ion enters mass analyzer, complete sample introduction.
Matrix Assisted Laser Desorption (MALDI) ion source sampling device sample introduction in a vacuum has vital effect, owing to testing sample (mostly being biological sample) directly can not be immediately transferred to high vacuum environment from atmospheric pressure environment, therefore sampling device needs to ensure that sample gradually adapts to high vacuum environment during atmospheric pressure environment enters into high vacuum environment, sample will not be produced and destroy so that affecting analysis result, it is thus desirable to find one can first carry out a kind of coarse vacuum excessively, and then enter the equipment of fine vacuum.
Summary of the invention
In view of this, need to overcome at least one in drawbacks described above of the prior art, the invention provides a kind of Matrix Assisted Laser Desorption ion source sampling device, there is the hollow part of chamber including inside, it is arranged on the Y-direction platform within described hollow part with the X being arranged on described Y-direction platform to platform, it is placed on the target groove being arranged on described X target groove platform on platform, be arranged on real-time hollow part internal and with described X to the relative top target drone structure of platform forward and act target drone structure, and be arranged on the cover plate at described hollow part top；It is provided with detection hole and described sample putting hole on described cover plate, at described sample putting hole, is provided with sample cover plate；Described X has hard-wired first block and the second block to platform, described top target drone structure has and the top target contact component of described first block dynamic Contact, described act target drone structure has and the act target contact component of described second block dynamic Contact, described act target contact component has act target contact front portion and contacts rear portion with lifting target, and described second block contacts anterior dynamic Contact during entering target and contacts rear portion dynamic Contact with described act target during moving back target with described act target；Described act target drone structure has act target platform, and described act target platform is upwards lifted described target groove during entering target and puts down downwards described target groove during moving back target and be placed on by target groove on described X target groove platform on platform；Described top target drone structure has top target parts, described top target parts upwards target groove described in jack-up and move downward during moving back target and loosen described target groove during entering target.
nullIn operation，When entering target position，X promotes described target groove to during precalculated position to platform and Y-direction platform，Described second block contacts front contact with the described act target of described act target contact component，The described act target platform in described act target drone structure is promoted upwards to hold up described target groove，When X continues motion to platform and Y-direction platform，Further such that described first block contacts with described top target contact component，Make target groove described in the described top target parts upwards jack-up of described top target drone structure，So that described target groove is upwards in close contact with described cover plate，Now sample is put into described target groove，Close described sample cover plate，Now，Described target groove and described cover plate and described sample cover plate form the first sealing chamber，It has corresponding evacuation through hole，So，This chamber can be carried out low vacuum treatment，And whole chamber also synchronizes carry out high vacuum；After pre-provisioning request to be achieved, when carrying out moving back target position, X is to platform and Y-direction platform rearward movement, described top target contact component has resilience force, therefore can withstand described first block together to move, described top target parts fall, described target groove is along with falling on above-mentioned act target platform, described second block retreats and contacts with described act target anterior disengaging therewith and then drives described act target to contact rear portion, described act target platform is made to drive described target groove to move to described X on the described target groove platform of platform, afterwards, X moves to the described detection hole site on described cover plate to platform and Y-direction platform, thus can carry out dissection process.
According in this patent background technology to described in prior art, due in corresponding resolving, if sample rapidly enters under high vacuum environment, inherently sample itself causes certain destruction, and testing result so also certainly exists the biggest error；And Matrix Assisted Laser Desorption ion source sampling device disclosed by the invention, make have reeded cover plate and target groove platform and target groove one dynamic transition coarse vacuum chamber of formation by utilizing to lift target drone structure and push up target mechanism kinematic, can effectively make sample carry out the dynamic sample adaptation process for vacuum, operation is more flexibly with convenient.
It addition, according to Matrix Assisted Laser Desorption ion source sampling device disclosed by the invention also there is following additional technical feature:
Further, described first block is one, described second block is two and is positioned at the both sides of the first block, described act target contact component be one and enter target process and move back during target with described first block dynamic Contact, described top target contact component be two and with described second block one_to_one corresponding dynamic Contact.
Dynamic Contact herein refers to on-fixed contact, and it can be in contact or contactless state along with motion each other or when being in different mode bits.
Further, described cover plate has a groove, described groove and described target groove dynamic Contact and formed with described sample cover plate and seal chamber, the vacuum interconnected hole of groove of described groove Zhong You UNICOM vacuum equipment.
The vacuum interconnected hole of described groove is there is, so that low vacuum treatment is convenient in described groove.
Further, described act target drone structure also has tray, and described top target drone structure is arranged on described tray.
Further, described act target drone structure has location bar, and the slide unit being arranged on described top target drone structure is arranged on the bar of described location and can move up and down.
Further, described act target contact component has the rotatable components of bearing.
Further, described act target contact component is roller construction.
Further, described top target parts have the rotatable components of bearing.
Further, described top target contact component is roller construction.
Rolling movement can more make mass motion smooth.
Preferably, the outer surface use elastomer of described roller construction is as contact site, so so that motion more has resiliency.
Further, described target groove platform has positioner.
Further, three, described positioner position locating dowel.
Further, described X includes power source and screw structure and linear slide rail slide block to platform or described Y-direction platform.
Further, described power source is motor.
Further, described sampling device also includes vacuum system, the vacuum interconnected hole of groove of described groove Zhong You UNICOM vacuum equipment.
Further, described vacuum system includes that molecular pump and mechanical pump, described molecular pump are connected with described chamber, and described mechanical pump is connected with described molecular pump and hole vacuum interconnected with described groove is connected.
Further, described act target platform in described act target drone structure is connected with lifting the rotation of target first connecting rod upper end, described act target first connecting rod lower end and described tray rotate and links, and by lift target second connecting rod be positioned at described act target contact component described act target contact anterior and described act target contact the rotation of rear portion and described act target contact component and the tray being positioned at described act target drone structure bottom link between and formation four-bar linkage structure.
Further, described top target drone structure also includes that base, described base and described act target drone structure are fixedly connected；Top target first connecting rod, target first connecting rod lower end, described top is connected with described base；Top target slide unit, described top target slide unit and the location bar being arranged on the target drone structure of described top and can move up and down；Top target second connecting rod, target second connecting rod top, described top and described top target slide unit top links, installation described top, bottom target contact component, middle part links in the middle part of the target first connecting rod of described top；Top target third connecting rod, pushes up target fourth link, and the two ends of described top target third connecting rod link with the top of described top target first connecting rod and one end of described top target fourth link respectively；Target fourth link one end, described top links jointly with the top of described top target slide unit and the top of described top target second connecting rod.
Aspect and advantage that the present invention adds will part be given in the following description, and part will become apparent from the description below, or is recognized by the practice of the present invention.
Accompanying drawing explanation
Above-mentioned and/or the additional aspect of the present invention and advantage will be apparent from easy to understand from the following description of the accompanying drawings of embodiments, wherein:
Fig. 1 Matrix Assisted Laser Desorption ion source sampling device overall schematic；
Fig. 2 Matrix Assisted Laser Desorption ion source sampling device (hiding cover plate) overall schematic；
Fig. 3 Matrix Assisted Laser Desorption ion source sampling device (without hollow part and for top target drone structure and lift target drone structure jack-up and when lifting target groove platform status) overall schematic；
Fig. 4 top target drone structure and act target drone structure one schematic diagram；
Fig. 5 X is to platform schematic diagram；
Fig. 6 Y-direction platform schematic diagram；
Fig. 7 top target structural scheme of mechanism；
Fig. 8 lifts target structural scheme of mechanism；
Fig. 9 cover plate schematic diagram；
nullIn figure，100 hollow parts，200 X are to platform，201 target groove platforms，202 first block 203 second blocks，204 positioners，300 Y-direction platforms,400 lift target drone structure，401 lift target platform，402 lift target contact component，4021 lift target contact front portion，4022 lift target contact rear portion，403 location bars，404 trays，405 lift target first connecting rod，406 lift target second connecting rod，500 top target drone structures，501 top target parts，502 top target contact components，503 top target slide units，504 bases，505 top target first connecting rods，506 top target second connecting rods，507 top target third connecting rods，508 top target fourth link，600 cover plates，601 detection holes，602 sample cover plates，603 sample putting holes，604 grooves，The 605 vacuum interconnected holes of groove.
Detailed description of the invention
Embodiments of the invention are described below in detail, and the example of described embodiment is shown in the drawings, and the most same or similar label represents same or similar element or has the element of same or like function.The embodiment described below with reference to accompanying drawing is exemplary, is only used for explaining the present invention, and is not construed as limiting the claims.
In describing the invention, it will be appreciated that, term " on ", D score, " end ", " top ", "front", "rear", " interior ", " outward ", " horizontal ", the orientation of the instruction such as " erecting " or position relationship be based on orientation shown in the drawings or position relationship, it is for only for ease of the description present invention and simplifies description, rather than instruction or hint indication device or element must have specific orientation, with specific azimuth configuration and operation, be therefore not considered as limiting the invention.
In describing the invention, it should be noted that unless otherwise clearly defined and limited, term " couples ", " connection ", " being connected ", should be interpreted broadly " connection ", " cooperation ", connects for example, it may be fixing, it is integrally connected, it is also possible to be to removably connect；It can be the connection of two element internals；Can be to be joined directly together, it is also possible to be indirectly connected to by intermediary；" coordinating " can be face and the coordinating of face, it is also possible to is point and the coordinating of face or line and face, also includes the cooperation of hole axle, for the ordinary skill in the art, and can be with concrete condition understanding above-mentioned term concrete meaning in the present invention.
The inventive concept of the present invention is as follows, as shown in figs 1-9, by utilizing act target drone structure 400 and top target drone structure 500 motion to make the cover plate 600 with groove 604 and target groove platform 201 and target groove form a dynamic transition coarse vacuum chamber, can effectively make sample carry out the dynamic sample adaptation process for vacuum, operation is more flexibly with convenient.
According to embodiments of the invention, as shown in figs 1-9, a kind of Matrix Assisted Laser Desorption ion source sampling device, there is the hollow part 100 of chamber including inside, it is arranged on the Y-direction platform 300 within described hollow part 100 with the X being arranged on described Y-direction platform 300 to platform 200, it is placed on the target groove being arranged on described X target groove platform 201 on platform 200, be arranged on described hollow part 100 internal and with described X to the relative top target drone structure 500 of platform 200 forward and act target drone structure 400, and be arranged on the cover plate 600 at described hollow part 100 top；It is provided with detection hole 601 and described sample putting hole 603 on described cover plate 600, at described sample putting hole, is provided with sample cover plate 602；Described X has hard-wired first block 202 and the second block 203 to platform 200, described top target drone structure 500 has and the top target contact component 502 of described first block 202 dynamic Contact, described act target drone structure 400 has and the act target contact component 402 of described second block 203 dynamic Contact, described act target contact component 402 has act target contact anterior 4021 and contacts rear portion 4022 with lifting target, and described second block 203 contacts anterior 4021 dynamic Contacts during entering target and contacts rear portion 4022 dynamic Contact with described act target during moving back target with described act target；Described act target drone structure 400 has act target platform 401, and described act target platform 401 is upwards lifted described target groove platform 201 during entering target and puts down downwards described target groove platform 201 during moving back target and be placed on by target groove on described X target groove platform 201 on platform 200；Described top target drone structure 500 has top target parts 501, described top target parts 501 upwards target groove platform 201 described in jack-up and move downward during moving back target and loosen described target groove platform 201 during entering target.
nullIn operation，When entering target position，During X promotes described target groove platform 401 to precalculated position to platform 200 and Y-direction platform 300，Described second block 203 contacts anterior 4021 contacts with the described act target of described act target contact component 402，The described act target platform 401 in described act target drone structure 400 is promoted upwards to hold up described target groove platform 401，When X continues motion to platform 200 and Y-direction platform 300，Further such that described first block 202 contacts with described top target contact component 501，Make target groove platform 201 described in the described top target parts 501 upwards jack-up of described top target drone structure 500，So that described target groove platform 201 is upwards in close contact with described cover plate 600，Now sample is put in the target groove in described target groove platform 201，Close described sample cover plate 602，Now，Described target groove platform 201 forms the first sealing chamber with described cover plate 600 and described sample cover plate 602，It has corresponding evacuation through hole 605，So，This chamber can be carried out low vacuum treatment，And whole chamber also synchronizes carry out high vacuum，As Figure 1-3；After pre-provisioning request to be achieved, when carrying out moving back target position, X is to platform 200 and Y-direction platform 300 rearward movement, described top target contact component 502 has resilience force, therefore can withstand described first block 202 together to move, described top target parts 501 fall, described target groove platform 201 is along with falling on described act target platform 401, described second block 203 retreats therewith and contacts anterior 4021 with described act target and departs from and then drive described act target to contact rear portion 4022, described act target platform 401 is made to drive described target groove platform 201 to move to described X on the described target groove platform of platform 200 201, afterwards, X moves to the position, described detection hole 601 on described cover plate 600 to platform 200 and Y-direction platform 300, thus can carry out dissection process.
It addition, according to Matrix Assisted Laser Desorption ion source sampling device disclosed by the invention also there is following additional technical feature:
Further, described first block 202 is one, described second block 203 is two and is positioned at the both sides of the first block 202, described top target contact component 52 be one and enter target process and move back during target with described first block 202 dynamic Contact, described act target contact component 402 be two and with described second block 203 one_to_one corresponding dynamic Contact, as shown in Fig. 4,5,7,8.
Dynamic Contact herein refers to on-fixed contact, and it can be in contact or contactless state along with motion each other or when being in different mode bits.
Further, described cover plate 600 has a groove 604, described groove 604 and described target groove platform 201 dynamic Contact and formed with described sample cover plate 602 and seal chamber, the vacuum interconnected hole of groove 605 of described groove 604 Zhong You UNICOM vacuum equipment, as shown in Figure 9.
The vacuum interconnected hole of described groove 605 is there is, so that low vacuum treatment is convenient in described groove 604.
Further, described act target drone structure 400 also has tray 404, described top target drone structure 500 is arranged on described tray 404, as shown in Fig. 4,7,8.
Further, described act target drone structure 400 has location bar 403, and the top target slide unit 503 being arranged on described top target drone structure 500 is arranged on described location bar 403 and can move up and down, such as Fig. 4, shown in 8.
Further, described act target contact component 402 has the rotatable components of bearing.
Further, described act target contact component 402 is roller construction, as shown in Figure 8.
Further, described top target parts 500 have the rotatable components of bearing.
Further, described top target contact component 502 is roller construction, as shown in Figure 7.
Rolling movement can more make mass motion smooth.
Preferably, the outer surface use elastomer of described roller construction is as contact site, so so that motion more has resiliency.
Further, described target groove platform 201 has positioner 204.
Further, described positioner 204 is three locating dowels, as shown in Figure 5.
Further, described X includes power source and screw structure and linear slide rail slide block to platform 200 or described Y-direction platform 300.
Further, described power source is motor.
Further, described sampling device also includes vacuum system, the vacuum interconnected hole of groove 605 of described groove 604 Zhong You UNICOM vacuum equipment.
Further, described vacuum system includes that molecular pump and mechanical pump, described molecular pump are connected with described chamber, and described mechanical pump is connected with described molecular pump and hole vacuum interconnected with described groove 605 is connected.
Further, described act target platform 401 in described act target drone structure 400 is connected with lifting the rotation of target first connecting rod 405 upper end, described act target first connecting rod 405 lower end rotates with described tray 404 and links, and by lift target second connecting rod 406 be positioned at described act target contact component 402 described act target contact anterior 4021 and described act target contact the rotation of rear portion 4022 and described act target contact component 402 and the tray 404 being positioned at described act target drone structure 400 bottom link between and formation four-bar linkage structure, as shown in Figure 8.
Further, described top target drone structure 500 also includes that base 504, described base 504 and described act target drone structure 500 are fixedly connected；Top target first connecting rod 506, target first connecting rod 506 lower end, described top is connected with described base 504；Top target slide unit 503, described top target slide unit 503 and the location bar 403 being arranged on described top target drone structure 500 and can move up and down；Top target second connecting rod 506, target second connecting rod 506 top, described top and described top target slide unit 503 top links, installation described top, bottom target contact component 502, middle part links in the middle part of described top target first connecting rod 505；Top target third connecting rod 507, pushes up target fourth link 508, and the two ends of described top target third connecting rod 507 link with the top of described top target first connecting rod 505 and one end of described top target fourth link 508 respectively；Target fourth link 508 one end, described top links jointly with the top of described top target slide unit 503 and the top of described top target second connecting rod 502.
Any mention that " embodiment ", " embodiment ", " illustrative examples " etc. mean to combine concrete component, structure or feature that this embodiment describes and be contained at least one embodiment of the present invention.In this specification, this schematic representation everywhere is not necessarily referring to identical embodiment.And, when combining any embodiment and describing concrete component, structure or feature, advocated, realize such component, structure or feature in conjunction with other embodiment and all fall within the scope of those skilled in the art.
Although the detailed description of the invention of the present invention is described in detail by the multiple illustrative examples with reference to the present invention, it must be understood that, those skilled in the art can be designed that multiple other improvement and embodiment, these improve and embodiment will fall within spirit and scope.Specifically, within the scope of aforementioned disclosure, accompanying drawing and claim, rational modification and improvement can be made in terms of the layout of parts and/or sub-combination layout, without departing from the spirit of the present invention.Except the modification in terms of parts and/or layout and improvement, its scope is defined by the appended claims and the equivalents thereof.
Claims (17)
1. a Matrix Assisted Laser Desorption ion source sampling device, it is characterized in that, there is the hollow part of chamber including inside, it is arranged on the Y-direction platform within described hollow part with the X being arranged on described Y-direction platform to platform, it is placed on the target groove being arranged on described X target groove platform on platform, be arranged on described hollow part internal and with described X to the relative top target drone structure of platform forward and act target drone structure, and be arranged on the cover plate at described hollow part top；
It is provided with detection hole and described sample putting hole on described cover plate, at described sample putting hole, is provided with sample cover plate；
Described X has hard-wired first block and the second block to platform, described top target drone structure has and the top target contact component of described first block dynamic Contact, described act target drone structure has and the act target contact component of described second block dynamic Contact, described act target contact component has act target contact front portion and contacts rear portion with lifting target, and described second block contacts anterior dynamic Contact during entering target and contacts rear portion dynamic Contact with described act target during moving back target with described act target；
Described act target drone structure has act target platform, and described act target platform is upwards lifted described target groove platform during entering target and puts down downwards described target groove during moving back target and be placed on by target groove on described X target groove platform on platform；
Described top target drone structure has top target parts, described top target parts upwards target groove described in jack-up and move downward during moving back target and loosen described target groove during entering target.
Matrix Assisted Laser Desorption ion source sampling device the most according to claim 1, it is characterized in that, described first block is one, described second block is two and is positioned at the both sides of the first block, described top target contact component be one and enter target process and move back during target with described first block dynamic Contact, described act target contact component be two and with described second block one_to_one corresponding dynamic Contact.
Matrix Assisted Laser Desorption ion source sampling device the most according to claim 1, it is characterized in that, described cover plate has a groove, described groove and described target groove platform dynamic Contact and formed with described sample cover plate and seal chamber, the vacuum interconnected hole of groove of described groove Zhong You UNICOM vacuum equipment.
Matrix Assisted Laser Desorption ion source sampling device the most according to claim 1, it is characterised in that described act target drone structure also has tray, described top target drone structure is arranged on described tray.
5., according to the Matrix Assisted Laser Desorption ion source sampling device described in claim 1, it is characterised in that described act target drone structure has location bar, the slide unit being arranged on described top target drone structure is arranged on the bar of described location and can move up and down.
Matrix Assisted Laser Desorption ion source sampling device the most according to claim 1, it is characterised in that described act target contact component has the rotatable components of bearing.
Matrix Assisted Laser Desorption ion source sampling device the most according to claim 6, it is characterised in that described act target contact component is roller construction.
Matrix Assisted Laser Desorption ion source sampling device the most according to claim 1, it is characterised in that described top target parts have the rotatable components of bearing.
Matrix Assisted Laser Desorption ion source sampling device the most according to claim 8, it is characterised in that described top target contact component is roller construction.
Matrix Assisted Laser Desorption ion source sampling device the most according to claim 1, it is characterised in that on described target groove platform, there is positioner.
11. Matrix Assisted Laser Desorption ion source sampling devices according to claim 10, it is characterised in that three, described positioner position locating dowel.
12. Matrix Assisted Laser Desorption ion source sampling devices according to claim 1, it is characterised in that described X includes power source and screw structure and linear slide rail slide block to platform or described Y-direction platform.
13. Matrix Assisted Laser Desorption ion source sampling devices according to claim 12, it is characterised in that described power source is motor.
14. Matrix Assisted Laser Desorption ion source sampling devices according to claim 1, it is characterised in that described sampling device also includes vacuum system, the vacuum interconnected hole of groove of described groove Zhong You UNICOM vacuum equipment.
15. Matrix Assisted Laser Desorption ion source sampling devices according to claim 14, it is characterized in that, described vacuum system includes that molecular pump and mechanical pump, described molecular pump are connected with described chamber, and described mechanical pump is connected with described molecular pump and hole vacuum interconnected with described groove is connected.
16. Matrix Assisted Laser Desorption ion source sampling devices according to claim 1, it is characterized in that, described act target platform in described act target drone structure is connected with lifting the rotation of target first connecting rod upper end, described act target first connecting rod lower end and described tray rotate and links, and by lift target second connecting rod be positioned at described act target contact component described act target contact anterior and described act target contact the rotation of rear portion and described act target contact component and the tray being positioned at described act target drone structure bottom link between and formation four-bar linkage structure.
17. Matrix Assisted Laser Desorption ion source sampling devices according to claim 1, it is characterised in that described top target drone structure also includes that base, described base and described act target drone structure are fixedly connected；Top target first connecting rod, target first connecting rod lower end, described top is connected with described base；Top target slide unit, described top target slide unit and the described location bar being arranged on described act target drone structure and can move up and down；Top target second connecting rod, described act target second connecting rod top and described top target slide unit top links, installation described top, bottom target contact component, middle part links in the middle part of described act target first connecting rod；Lifting target third connecting rod, lift target fourth link, one end with the top of described act target first connecting rod and described act target fourth link respectively, the two ends of described act target third connecting rod links；Described act target fourth link one end links jointly with the top on the top of described act target slide unit and described act target second connecting rod.
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| CN107907584A (en) * | 2017-12-15 | 2018-04-13 | 德信致安（天津）科技有限公司 | A kind of Matrix Assisted Laser Desorption ion gun vacuum sampling device |
| CN108022822A (en) * | 2017-12-06 | 2018-05-11 | 江苏天瑞仪器股份有限公司福建分公司 | The in-out apparatus of MALDI TOF MS instrument sample target |
| CN109270285A (en) * | 2018-11-19 | 2019-01-25 | 厦门元谱生物科技有限公司 | A kind of vacuum sampling device |
| CN111223742A (en) * | 2018-11-23 | 2020-06-02 | 广州禾信康源医疗科技有限公司 | Sample target lifting mechanism, mass spectrometer sample changing device and mass spectrometer sample changing method |
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Application publication date: 20160824 |