CN105873583A - 用于降低慢性肾病患者的心力衰竭的枸橼酸铁 - Google Patents

用于降低慢性肾病患者的心力衰竭的枸橼酸铁 Download PDF

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Publication number
CN105873583A
CN105873583A CN201480072217.1A CN201480072217A CN105873583A CN 105873583 A CN105873583 A CN 105873583A CN 201480072217 A CN201480072217 A CN 201480072217A CN 105873583 A CN105873583 A CN 105873583A
Authority
CN
China
Prior art keywords
ferric citrate
iron
patient
ckd
serum
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201480072217.1A
Other languages
English (en)
Chinese (zh)
Inventor
恩里克·普拉多苏
罗恩·本图尔
詹姆斯·F·奥利维耶罗三世
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Keryx Biopharmaceuticals Inc
Original Assignee
Keryx Biopharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Keryx Biopharmaceuticals Inc filed Critical Keryx Biopharmaceuticals Inc
Publication of CN105873583A publication Critical patent/CN105873583A/zh
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/26Iron; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
CN201480072217.1A 2013-11-04 2014-11-03 用于降低慢性肾病患者的心力衰竭的枸橼酸铁 Pending CN105873583A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361899866P 2013-11-04 2013-11-04
US61/899,866 2013-11-04
PCT/US2014/063643 WO2015066593A1 (en) 2013-11-04 2014-11-03 Ferric citrate for reducing cardiac failure in chronic kidney disease patients

Publications (1)

Publication Number Publication Date
CN105873583A true CN105873583A (zh) 2016-08-17

Family

ID=53005244

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201480072217.1A Pending CN105873583A (zh) 2013-11-04 2014-11-03 用于降低慢性肾病患者的心力衰竭的枸橼酸铁

Country Status (15)

Country Link
US (3) US20160256486A1 (enExample)
EP (2) EP3747432A1 (enExample)
JP (3) JP2016535780A (enExample)
KR (1) KR102392441B1 (enExample)
CN (1) CN105873583A (enExample)
AU (1) AU2014341975A1 (enExample)
BR (1) BR112016009901A8 (enExample)
CA (1) CA2928200A1 (enExample)
EA (1) EA201690926A1 (enExample)
HK (1) HK1223031A1 (enExample)
IL (1) IL245317A0 (enExample)
MX (1) MX2016005734A (enExample)
SG (1) SG11201603091QA (enExample)
TW (2) TWI744215B (enExample)
WO (1) WO2015066593A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113613662A (zh) * 2018-10-29 2021-11-05 法码科思莫斯控股有限公司 用羧基麦芽糖铁治疗铁缺乏

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2010276242B2 (en) 2009-07-21 2014-05-29 Keryx Biopharmaceuticals, Inc. Ferric citrate dosage forms
DK3287133T3 (da) 2013-06-05 2019-07-01 Tricida Inc Proton-bindende polymerer til oral indgivelse
WO2015198304A1 (en) 2014-06-22 2015-12-30 Dexcel Pharma Technologies Ltd. Pharmaceutical compositions comprising ferric citrate and methods for the production thereof
KR102625115B1 (ko) 2014-12-10 2024-01-12 트리시다, 인크. 경구 투여용 양성자-결합 폴리머
KR102655774B1 (ko) 2016-05-06 2024-04-05 트리시다, 인크. 산-염기 장애의 치료를 위한 조성물 및 방법
IL319146A (en) 2017-11-03 2025-04-01 Tricida Inc Compositions for and method of treating acid-base disorders
CN114286682A (zh) * 2019-02-09 2022-04-05 法码科思莫斯控股有限公司 治疗具有心血管不良事件风险的个体的铁缺乏以及用于治疗心房颤动的铁
TW202313072A (zh) * 2021-05-27 2023-04-01 美商凱立克斯生物製藥股份有限公司 檸檬酸鐵之兒科調配物

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101374416A (zh) * 2006-01-30 2009-02-25 环亚有限公司 逆转、防止、延迟或稳定软组织钙化的方法
CN102573807A (zh) * 2009-07-21 2012-07-11 凯克斯生物制药公司 柠檬酸铁剂型
CN104884055A (zh) * 2012-06-21 2015-09-02 凯克斯生物制药公司 柠檬酸铁在治疗慢性肾脏疾病患者中的应用

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SE351366B (enExample) * 1965-06-08 1972-11-27 Teikoku Hormone Mfg Co Ltd
US20050203169A1 (en) * 2001-08-06 2005-09-15 Moskowitz David W. Methods and compositions for treating diseases associated with excesses in ACE
US8093423B2 (en) 2003-02-19 2012-01-10 Globoasia, Llc Pharmaceutical-grade ferric organic compounds, uses thereof and method of making same
TWI335218B (en) 2003-02-19 2011-01-01 Panion & Bf Biotech Inc Ferric organic compounds, uses thereof and methods of making same
MX2008002360A (es) * 2005-08-18 2008-04-29 Globoasia Llc Compuestos organicos ferricos grado farmaceutico, uso de los mismos y metodos para elaborar los mismos.
KR20080106506A (ko) * 2006-01-30 2008-12-08 글로보아시아 엘엘씨 만성 신장병의 치료 방법
EP2590655B1 (en) * 2010-07-07 2015-06-24 Ardelyx, Inc. Compounds and methods for inhibiting phosphate transport

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101374416A (zh) * 2006-01-30 2009-02-25 环亚有限公司 逆转、防止、延迟或稳定软组织钙化的方法
CN101378658A (zh) * 2006-01-30 2009-03-04 环亚有限公司 治疗慢性肾病的方法
CN102573807A (zh) * 2009-07-21 2012-07-11 凯克斯生物制药公司 柠檬酸铁剂型
CN104884055A (zh) * 2012-06-21 2015-09-02 凯克斯生物制药公司 柠檬酸铁在治疗慢性肾脏疾病患者中的应用

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113613662A (zh) * 2018-10-29 2021-11-05 法码科思莫斯控股有限公司 用羧基麦芽糖铁治疗铁缺乏
US11806329B2 (en) 2018-10-29 2023-11-07 Pharmacosmos Holding A/S Treating iron deficiency with ferric carboxymaltose
US12295934B2 (en) 2018-10-29 2025-05-13 Pharmacosmos Holding A/S Treating iron deficiency with ferric carboxymaltose
US12303486B2 (en) 2018-10-29 2025-05-20 Pharmacosmos Holding A/S Treating iron deficiency with ferric carboxymaltose

Also Published As

Publication number Publication date
WO2015066593A1 (en) 2015-05-07
BR112016009901A8 (pt) 2020-04-14
IL245317A0 (en) 2016-06-30
TW201609088A (zh) 2016-03-16
KR102392441B1 (ko) 2022-05-02
TWI744215B (zh) 2021-11-01
US20250360167A1 (en) 2025-11-27
HK1223031A1 (zh) 2017-07-21
KR20160096597A (ko) 2016-08-16
SG11201603091QA (en) 2016-05-30
JP2021073230A (ja) 2021-05-13
EP3065734A4 (en) 2017-05-17
EP3065734A1 (en) 2016-09-14
JP2016535780A (ja) 2016-11-17
US20190307791A1 (en) 2019-10-10
EA201690926A1 (ru) 2016-09-30
CA2928200A1 (en) 2015-05-07
EP3747432A1 (en) 2020-12-09
JP6828100B2 (ja) 2021-02-10
AU2014341975A1 (en) 2016-05-19
US20160256486A1 (en) 2016-09-08
JP2019206562A (ja) 2019-12-05
MX2016005734A (es) 2016-11-08
TW202203910A (zh) 2022-02-01

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PB01 Publication
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SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20160817

RJ01 Rejection of invention patent application after publication