CN105853935B - 一种治疗心脑系统疾病的中药组合物 - Google Patents

一种治疗心脑系统疾病的中药组合物 Download PDF

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CN105853935B
CN105853935B CN201610401663.3A CN201610401663A CN105853935B CN 105853935 B CN105853935 B CN 105853935B CN 201610401663 A CN201610401663 A CN 201610401663A CN 105853935 B CN105853935 B CN 105853935B
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parts
fried
root
raw
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CN105853935A (zh
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牟宝成
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Gansu Debaotang Biotechnology Co ltd
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Abstract

本发明公开了提供一种治疗心脑系统疾病的中药组合物，对于因气血亏损、脾胃虚弱、气滞血瘀等原因所引起的胸痹、胸痛、胸闷、气短、心悸、心慌、头晕、失眠、中风等病症有治疗效果。由下述原料制成：生黄芪，太子参，生山药，炒白术，炙甘草，当归，熟地黄，炒白芍，龙眼肉，广木香，制香附，陈皮，血丹参，川芎，乳香，没药，郁金，桃仁，红花，生地黄，牡丹皮，赤芍，灵芝，炒枣仁，柏子仁，茯神，炒杜仲，狗脊，麦冬，枸杞子，龟板，炙五味子，山茱萸，炒厚朴，茯苓，薏苡仁，生山楂，炒神曲，柴胡。

Description

一种治疗心脑系统疾病的中药组合物
技术领域
本发明涉及中药领域，尤其涉及治疗心脑系统疾病的中药组合物。
背景技术
心脑系统疾病，是指心脑功能失常和病理变化引起的一类疾病。心脑疾病一直号称威胁人类健康的头号杀手，预防和治疗心脑血管疾病是每位医生的使命和职责。随着社会生活水平的提高和工作节奏的加快，心脑系统疾病已经成为威胁中老年人们健康和长寿的第一号杀手，据有关调查报告显示，我国心脑系统疾病患者已超过2亿人，并且每天易2万人的速度递增，如何有效预防和治疗已引起国家的高度重视，目前治疗心脑系统疾病比如胸痹、胸痛、胸闷、气短、心悸、心慌、头晕、失眠、中风的药物较多，各种药物各自具有自己的特点，但也同时存在一定的不足，所以各种药物能够在市场上并存，并为患者所接受。
发明内容
本发明所要解决的技术问题是提供一种治疗心脑系统疾病的中药组合物，对于因气血亏损、脾胃虚弱、气滞血瘀等原因所引起的胸痹、胸痛、胸闷、气短、心悸、心慌、头晕、失眠、中风等病症有治疗效果。
本发明的技术方案是，由下述重量配比的原料制成：生黄芪15-45份，太子参15-45份，生山药15-45份，炒白术8-24份，炙甘草4-12份，当归7-23份，熟地黄5-15份，炒白芍8-24份，龙眼肉6-18份，广木香4-12份，制香附4-12份，陈皮6-18份，血丹参15-45份，川芎4-12份，乳香4-12份，没药4-12份，郁金6-18份，桃仁4-12份，红花4-12份，生地黄5-15份，牡丹皮6-18份，赤芍6-18份，灵芝6-18份，炒枣仁5-15份，柏子仁5-15份，茯神8-24份，炒杜仲6-18份，狗脊6-18份，麦冬5-15份，枸杞子6-18份，龟板6-18份，炙五味子5-15份，山茱萸6-18份，炒厚朴5-15份，茯苓8-24份，薏苡仁6-18份，生山楂6-18份，炒神曲8-24份，柴胡6-18份。
优选的，所述中药组合物由下述重量配比的原料制成：生黄芪23-37份，太子参23-37份，生山药23-37份，炒白术12-20份，炙甘草6-10份，当归11-19份，熟地黄8-12份，炒白芍12-20份，龙眼肉9-15份，广木香6-10份，制香附6-10份，陈皮9-15份，血丹参23-37份，川芎6-10份，乳香6-10份，没药6-10份，郁金9-15份，桃仁6-10份，红花6-10份，生地黄8-12份，牡丹皮9-15份，赤芍9-15份，灵芝9-15份，炒枣仁8-12份，柏子仁8-12份，茯神12-20份，炒杜仲9-15份，狗脊9-15份，麦冬8-12份，枸杞子9-15份，龟板9-15份，炙五味子8-12份，山茱萸9-15份，炒厚朴8-12份，茯苓12-20份，薏苡仁9-15份，生山楂9-15份，炒神曲12-20份，柴胡9-15份。
优选的，该中药组合物由下述重量配比的原料制成：生黄芪30份，太子参30份，生山药30份，炒白术16份，炙甘草8份，当归15份，熟地黄10份，炒白芍16份，龙眼肉12份，广木香8份，制香附8份，陈皮12份，血丹参30份，川芎8份，乳香8份，没药8份，郁金12份，桃仁8份，红花8份，生地黄10份，牡丹皮12份，赤芍12份，灵芝12份，炒枣仁10份，柏子仁10份，茯神16份，炒杜仲12份，狗脊12份，麦冬10份，枸杞子12份，龟板12份，炙五味子10份，山茱萸12份，炒厚朴10份，茯苓16份，薏苡仁12份，生山楂12份，炒神曲16份，柴胡12份。
本发明选用39种中药：
1生黄芪
性味归经 甘，微温。归脾，肺经。
功效 补气生阳，益卫固表，托毒生肌，利水退肿。
2太子参
性味归经 甘，微苦，微温。归脾，肺经。
功效 大补元气，补脾益肺，生津止渴，安神增智。
3生山药
性味归经 甘，平。归脾，肺，肾经。
功效 益气养阴，补脾肺肾。
4炒白术
性味归经 苦，甘，温。归脾胃经。
功效 补气健脾，燥湿利水，止汗安胎。
5 炙甘草
性味归经 甘，平。归心，脾，肺，肾经。
功效 补脾益气，润肺止咳，缓急止痛，缓和药性。
6当归
性味归经 甘，辛，温。归肝，心，脾经。
功效 补血，活血，止痛润肠。
7熟地黄
性味归经 甘，微温。归甘，肾经。
功效 养血滋阴，补精益髓
8 炒白芍
性味归经 苦，酸，微寒，归肝脾经。
功效 养血敛阴，柔肝止痛，平阴肝阳。
9龙眼肉
性味归经 甘，温。归心脾经。
功效 补心脾，益气血。
10广木香
性味归经 辛，苦，温。归脾，胃，大肠，胆经。
功效 行气，调中，止痛。
11制香附
性味归经 辛，微苦，微甘，平。归肝，三焦经
功效 疏肝理气，调经止痛。
12陈皮
性味归经 辛，苦，温。 归脾，肺经。
功效 理气，调中，燥湿，化痰
13血丹参
性味归经 苦，微寒。归心，心包，肝经。
功效 活血化瘀，凉血消痛，养血安神。
14川芎
性味归经 辛，温，归肝。胆，心包经。
功效 活血行气，祛风止痛。
15乳香
性味归经 辛，苦，温。归心，肝，脾经
功效 活血止痛，消肿生肌。
16没药
性味归经 苦，平。归心，肝，脾经。
功效 活血止痛，消肿生肌。
17郁金
性味归经 辛，苦，寒。归心，甘，胆经。
功效 活血止痛，。行气解郁，凉血清心，利胆退黄。
18桃仁
性味归经 苦，平。归心，甘，肺，大肠经。
功效 活血化瘀，润肠通便。
19红花
性味归经 辛，温，归心，肝经。
功效 活血祛瘀，通经。
20生地黄
性味归经 甘，苦，寒。归心，肝，肾经。
功效 清热凉血，养阴生津。
21牡丹皮
性味归经 苦，辛，微寒。归心，肝，肾经。
功效 清热凉血，活血散瘀。
22赤芍
性味归经 苦，微寒。归肝经
功效 清热凉血，祛瘀止痛。
23炒枣仁
性味归经 甘，平。归心，肝经。
功效 养心安神，敛汗。
24柏子仁
性味归经 甘，平。归心，肾，大肠经。
功效 养心安神，润肠通便。
25灵芝
性味归经 苦，平。归心，肺，肝，肾经。
功效 宁心安神，健脾益胃。
26茯神
性味归经 甘，平。
功效 宁心安神
27炒杜仲
性味归经 甘，温。归肝，肾经。
功效 补肝肾，强筋骨，安胎。
28狗脊
性味归经 苦，甘，温。 归肝，肾经。
功效 补肝肾，强腰膝，祛风湿。
29麦冬
性味归经 甘，微苦，微寒。归肺，心，胃经。
功效 润肺养阴，益胃生津，清心除烦。
30枸杞子
性味归经 甘，平。归甘，肾，肺经。
功效 滋阴补肝，明目，润肺。
31龟板
性味归经 甘，咸，寒，归肝，肾，心经。
功效 滋阴潜阳，益肾健骨，养血补心。
32炙五味子
性味归经 酸，温，归肺，肾，心经。
功效 敛肺滋肾，生津敛汗，涩精止泻，宁心安神。
33山茱萸
性味归经 酸，微温。归肝，肾经。
功效 补益肝肾，收敛固涩。
34炒厚朴
性味归经 苦，辛，温。归脾，胃，肺，大肠经。
功效 行气，燥湿，消积，平喘。
35茯苓
性味归经 甘，淡，平。归心，脾，肾经。
功效 利水渗湿，健脾，安神。
36薏苡仁
性味归经 甘，淡，微寒。归脾，胃，肺经。
功效 利水渗湿，健脾，清热排脓。
37生山楂
性味归经 酸，甘，微温。归脾，微，肝经。
功效 消食化积，活血散瘀。
38炒神曲
性味归经 甘，辛，温。归脾，胃经。
功效 消食和胃
39柴胡
性味归经 苦，辛，微寒。归心，包络，甘，三焦，胆经。
功效 和解退热，疏肝解郁，升举阳气。
本发明的技术效果是，心脑系统疾病多为本虚、标实证，本虚即气虚，标实即血瘀，气愈虚而血愈瘀，阳气足则血瘀自解，补元气尤其是补元气中的上焦宗气，是本组合物用于康复心脑系统疾病的主体指导思想。宗气为全身诸气之纲领，同时为全身血脉之纲领。补养人体宗气对于预防，治疗，康复心脑系统疾病具有根本的意义。
本组合物整体观念比较强，七分补气，三分补血，“补，通”理念明确，益气，活血，补而不滞，整体调理，从根本上使人体阴阳、气血、脏腑达到平衡，令气血通畅，使精血滋养全身，促进血液循环。
心脑系统疾病范围大，一般简单的药物组合是无法发挥出最佳效果，本组合物药味较多，生黄芪，太子参，生山药，炒白术，当归，熟地黄，炒白芍，龙眼肉具有益气补血的功能；广木香，制香附，陈皮，血丹参，川芎，乳香，没药，郁金，桃仁，红花，赤芍具有理气，清热凉血，活血化瘀，行气止痛的功效，灵芝，炒枣仁，柏子仁，茯神，炒杜仲，狗脊，麦冬，枸杞子，龟板，炙五味子，山茱萸，炒厚朴，茯苓，薏苡仁，生山楂，炒神曲，柴胡具有安神养心，滋阴补肾助阳，消食化积和胃，疏肝理气，利水渗湿，健脾功效的功能，甘草具有补脾益气，润肺止咳，缓急止痛，缓和药性的功能。用药合理，主次明确，是目前预防和治疗心脑系统疾病领域的较佳组合物。
采用较为常见的中草药作为原料，成本低廉，易于制作，具有益气补血，活血化瘀，滋阴补肾，助阳，健脾，燥湿，安神养心，行气止痛，消食化滞，疏肝理气等功能，可以预防和治疗胸痹，胸痛，胸闷，气短，心悸，心慌，头晕，失眠，中风等病症。
本中药组合物的制备方法是，将所述原料药烘干粉碎成细粉，然后经180目箩筛选，再收集药粉后混合均匀，然后用钴-60伽马射线进行辐射灭菌，最后充装胶囊即成。
以下通过试验来说明本发明药物所具有的有益效果，该试验例为本发明药物的临床疗效试验。
试验例
1收治心脑系统疾病患者1500例；
2诊断标准
胸痹，胸痛，胸闷，气短，心悸，心慌，头晕，失眠，中风等症状；
3治疗方法
口服一日三次，一次4-6克，饭后服用，一个月为一个疗程。
4疗效评定标准
心脑系统症状消除为治愈；心脑系统症状明显改善为有效。
5治疗效果
1500名患者服用三个疗程，治疗结果如下：有效率98%，治愈率95%。
具体实施方式
实施例1
一种治疗心脑系统疾病的中药组合物，由下述重量配比的原料制成：生黄芪30份，太子参30份，生山药30份，炒白术16份，炙甘草8份，当归15份，熟地黄10份，炒白芍16份，龙眼肉12份，广木香8份，制香附8份，陈皮12份，血丹参30份，川芎8份，乳香8份，没药8份，郁金12份，桃仁8份，红花8份，生地黄10份，牡丹皮12份，赤芍12份，灵芝12份，炒枣仁10份，柏子仁10份，茯神16份，炒杜仲12份，狗脊12份，麦冬10份，枸杞子12份，龟板12份，炙五味子10份，山茱萸12份，炒厚朴10份，茯苓16份，薏苡仁12份，生山楂12份，炒神曲16份，柴胡12份。
其制备方法是，将所述原料药烘干粉碎成细粉，然后经180目箩筛选，再收集药粉后混合均匀，然后用钴-60伽马射线进行辐射灭菌，最后充装胶囊即成。
实施例2
一种治疗心脑系统疾病的中药组合物，由下述重量配比的原料制成：生黄芪23份，太子参23份，生山药23份，炒白术12份，炙甘草6份，当归11份，熟地黄8份，炒白芍12份，龙眼肉9份，广木香6份，制香附6份，陈皮9份，血丹参23份，川芎6份，乳香6份，没药6份，郁金9份，桃仁6份，红花6份，生地黄8份，牡丹皮9份，赤芍9份，灵芝9份，炒枣仁8份，柏子仁8份，茯神12份，炒杜仲9份，狗脊9份，麦冬8份，枸杞子9份，龟板9份，炙五味子8份，山茱萸9份，炒厚朴8份，茯苓12份，薏苡仁9份，生山楂9份，炒神曲12份，柴胡9份。
其制备方法与实施例1相同。
实施例3
一种治疗心脑系统疾病的中药组合物，由下述重量配比的原料制成：生黄芪37份，太子参37份，生山药37份，炒白术20份，炙甘草10份，当归19份，熟地黄12份，炒白芍20份，龙眼肉15份，广木香10份，制香附10份，陈皮15份，血丹参37份，川芎10份，乳香10份，没药10份，郁金15份，桃仁10份，红花10份，生地黄12份，牡丹皮15份，赤芍15份，灵芝15份，炒枣仁12份，柏子仁12份，茯神20份，炒杜仲15份，狗脊15份，麦冬12份，枸杞子15份，龟板15份，炙五味子12份，山茱萸15份，炒厚朴12份，茯苓20份，薏苡仁15份，生山楂15份，炒神曲20份，柴胡15份。
其制备方法与实施例1相同。

Claims (3)

1.一种治疗心脑系统疾病的中药组合物，其特征在于，该中药组合物由下述重量配比的原料制成：生黄芪15-45份，太子参15-45份，生山药15-45份，炒白术8-24份，炙甘草4-12份，当归7-23份，熟地黄5-15份，炒白芍8-24份，龙眼肉6-18份，广木香4-12份，制香附4-12份，陈皮6-18份，血丹参15-45份，川芎4-12份，乳香4-12份，没药4-12份，郁金6-18份，桃仁4-12份，红花4-12份，生地黄5-15份，牡丹皮6-18份，赤芍6-18份，灵芝6-18份，炒枣仁5-15份，柏子仁5-15份，茯神8-24份，炒杜仲6-18份，狗脊6-18份，麦冬5-15份，枸杞子6-18份，龟板6-18份，炙五味子5-15份，山茱萸6-18份，炒厚朴5-15份，茯苓8-24份，薏苡仁6-18份，生山楂6-18份，炒神曲8-24份，柴胡6-18份。
2.根据权利要求1所述的中药组合物，其特征在于，该中药组合物由下述重量配比的原料制成：生黄芪23-37份，太子参23-37份，生山药23-37份，炒白术12-20份，炙甘草6-10份，当归11-19份，熟地黄8-12份，炒白芍12-20份，龙眼肉9-15份，广木香6-10份，制香附6-10份，陈皮9-15份，血丹参23-37份，川芎6-10份，乳香6-10份，没药6-10份，郁金9-15份，桃仁6-10份，红花6-10份，生地黄8-12份，牡丹皮9-15份，赤芍9-15份，灵芝9-15份，炒枣仁8-12份，柏子仁8-12份，茯神12-20份，炒杜仲9-15份，狗脊9-15份，麦冬8-12份，枸杞子9-15份，龟板9-15份，炙五味子8-12份，山茱萸9-15份，炒厚朴8-12份，茯苓12-20份，薏苡仁9-15份，生山楂9-15份，炒神曲12-20份，柴胡9-15份。
3.根据权利要求1或2所述的中药组合物，其特征在于，该中药组合物由下述重量配比的原料制成：生黄芪30份，太子参30份，生山药30份，炒白术16份，炙甘草8份，当归15份，熟地黄10份，炒白芍16份，龙眼肉12份，广木香8份，制香附8份，陈皮12份，血丹参30份，川芎8份，乳香8份，没药8份，郁金12份，桃仁8份，红花8份，生地黄10份，牡丹皮12份，赤芍12份，灵芝12份，炒枣仁10份，柏子仁10份，茯神16份，炒杜仲12份，狗脊12份，麦冬10份，枸杞子12份，龟板12份，炙五味子10份，山茱萸12份，炒厚朴10份，茯苓16份，薏苡仁12份，生山楂12份，炒神曲16份，柴胡12份。
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