CN105853867A - Medicinal composition for treating kidney-yang insufficiency and qi-blood deficiency - Google Patents

Medicinal composition for treating kidney-yang insufficiency and qi-blood deficiency Download PDF

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Publication number
CN105853867A
CN105853867A CN201610315727.8A CN201610315727A CN105853867A CN 105853867 A CN105853867 A CN 105853867A CN 201610315727 A CN201610315727 A CN 201610315727A CN 105853867 A CN105853867 A CN 105853867A
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parts
kidney
yang
blood deficiency
blood
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甘铁汉
韩宇强
莫合军
陆明艳
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GUANGXI BAIQI PHARMACEUTICAL Co Ltd
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GUANGXI BAIQI PHARMACEUTICAL Co Ltd
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Abstract

The invention discloses a medicinal composition for treating kidney-yang insufficiency and qi-blood deficiency. The medicinal composition is prepared from the following raw material medicines in parts by weight: 3-5 parts of cornu corvi nippon parvum, 5-7 parts of bombyxmori, 32-38 parts of herba epimedii, 18-22 parts of semen allii tuberose, 18-22 parts of morinda officinalis, 18-22 parts of cistanche deserticola, 18-22 parts of cuscuta chinensis, 12-16 parts of eucommia ulmoides, 12-16 parts of dipsacus asper, 3-5 parts of cinnamomum cassia, 5-7 parts of dog penis and testis, 5-7 parts of gecko, 11-15 parts of ginseng, 12-16 parts of astragalus membranaceus, 12-16 parts of atractylodes macrocephala, 12-16 parts of alpinia oxyphylla, 11-15 parts of Chinese yam, 11-15 parts of lycium barbarum, 11-15 parts of polygonatum sibiricum (prepared), 11-15 parts of proposed polygonum multiflorum, 11-15 parts of glossy privet fruit, 11-15 parts of prepared rehmannia roots, 11-15 parts of lindera aggregate, 11-15 parts of poria cocos and 4.3-6.3 parts of liquorice. To overcome the defects of conventional medicines for treating kidney-yang insufficiency and qi-blood deficiency, the medicinal composition which is relatively good in effect in treating kidney-yang insufficiency and qi-blood deficiency is provided.

Description

A kind of pharmaceutical composition treating insufficiency of kidney-YANG and QI and blood deficiency
Technical field
The present invention relates to technical field of Chinese medicines, be specifically related to a kind of insufficiency of kidney-YANG and QI and blood deficiency for the treatment of Pharmaceutical composition.
Background technology
The kidney being the origin of congenital constitution, the spleen being the foundation of acquired constitution.God client, the raw marrow of bone, the raw brain of marrow;The spleen has the function to transport and transform nutrients Receiving food, blood yang-energy, only kidney qi enrich, and transporting and transforming function of the spleen and stomach is healthy and vigorous, and human body could negative and positive be coordinated, QI and blood Alternate, healthy and strong, intelligence is vigorous, energetic.If kidney qi is weak, teenager, then can go out Existing " five kinds of growth retardation ";At teenager, then there will be hypoevolutism or dysplasia, and to growing up, due to Kidney qi is weak, then male's libido can be made cold, then not there will be senilism to old age, and dedentition is turned white, note Recall power to go down, the deficient symptom of sequence such as lumbago cold extremities.As the saying goes that ten men nine are empty, and main table of suffering from a deficiency of the kidney Be now insufficiency of kidney-YANG, and press the viewpoint of modern Chinese medicine theoretical research, the kidney yang of broad sense then include hypothalamus- Hypophysis cerebri-adrenal gland-gonad, spleen then refers to spleen, stomach, intestinal and spreads all over the lymphsystem of whole body, blood Fluid circulation.Insufficiency of kidney-YANG, then endocrine function is low;Insufficiency of the spleen then dyspepsia, absorbs not exclusively, Hemopoietic function is low.
That treats is warming the kidney to invigorate YANG, element culturing fixed folder, warming middle-JIAO and strengthening the spleen, vigorate qi and replenish the blood at all.Till root According to Traditional Chinese medical theory, in ancient times on the basis of tonifying YANG prescription, through plus-minus prescription, and clinical expert is examined Fixed, meet the traditional Chinese medical science principles of formulating prescriptions.
At present, insufficiency of kidney-YANG and QI and blood deficiency have been studied by the traditional Chinese medical science, such as publication number CN105106650A, Disclosing a kind of medicine treating insufficiency of kidney-YANG and QI and blood deficiency, it is mainly by following bulk drugs system Become: Fructus Evodiae 5-10g, Fructus Psoraleae 5-10g, Semen Cuscutae 5-10g, Cortex Cinnamomi 5-10g, Fructus Foeniculi 5-10g, With the supporing yang compatibility of drugs of warm nature, there is warming and recuperating the kidney-YANG, adjust Liver and kidney effect.And for example publication number CN1626230A, discloses a kind of Chinese medicine glue treating insufficiency of kidney-YANG and QI and blood deficiency blood deficiency associated diseases Capsule, this Chinese medicinal capsule is loaded capsule by Chinese medicine powder and makes, and its Chinese medicine powder is by Radix Ginseng, Solenognathus, deer Young pilose antler, Testis Caprae seu Ovis, Herba Cistanches, Semen Cuscutae, Fructus Lycii, Fructus Corni, the Cortex Eucommiae, Radix Et Rhizoma Rhei, Radix Rehmanniae, five Taste, Stigma Croci and Lac regis apis lyophilized powder are made, and this Chinese medicinal capsule can be effectively used for treatment because of kidney yang not Decline caused various diseases enough with QI and blood deficiency, asthenia of qi and blood.The traditional Chinese medical science is of extensive knowledge and profound scholarship, to insufficiency of kidney-YANG and The research of QI and blood deficiency is also endless.
Summary of the invention
The technical problem to be solved in the present invention is to overcome existing treatment insufficiency of kidney-YANG and QI and blood deficiency medicine Deficiency, it is provided that one treats insufficiency of kidney-YANG and the preferable pharmaceutical composition of QI and blood deficiency effect.
In pharmaceutical composition of the present invention, the consumption of each component is that inventor draws through a large amount of practice summaries , it is made up of the crude drug of following weight parts:
Preferably, it is made up of the crude drug of following weight parts:
The dosage form of pharmaceutical composition of the present invention can be the doctors such as oral liquid, capsule, tablet, decoction Acceptable dosage form on, their preparation method, supplementary product consumption are carried out by existing common process.
Pharmaceutical composition of the present invention is prepared the most in accordance with the following methods:
Above 25-component, takes Bombycis mori, Gecko, Testis et Pentis Canis, Cornu Cervi Pantotrichum chopping, mixing, steams 30 points Clock, with Chinese liquor (50 degree) the 32 airtight dipping of times amount 15 days, filters, and filtrate is standby;Take Herba Epimedii, Radix Ginseng, Radix Morindae Officinalis, Semen Allii Tuberosi, Herba Cistanches, Semen Cuscutae, the Cortex Eucommiae, Radix Dipsaci are ground into coarse powder, use 65% (v/v) alcohol dipping, after 48 hours, carries out percolation with the speed of 2-3ml per minute, and collection is oozed Filtering liquid, medicinal residues are standby;Take the Rhizoma Atractylodis Macrocephalae, Fructus Alpiniae Oxyphyllae, Cortex Cinnamomi powder are broken into coarse powder, extract volatile oil, distillation After the another device of aqueous solution preserve, medicinal residues are standby;Merge above-mentioned medicinal residues, and 10 tastes such as remaining Rhizoma Polygonati, Boiling secondary (10 times amount, 8 times amount), each 2 hours, collecting decoction, filter, filtrate Merging with the aqueous solution after above-mentioned distillation, being concentrated into relative density is 1.10 (70-80 DEG C), lets cool, Adding ethanol makes alcohol content reach 65%, stirs evenly, and stands 24 hours, takes supernatant and merge with above-mentioned percolate, Decompression recycling ethanol to relative density is 1.05 (70-80 DEG C), lets cool, and stands 24 hours, filters, Taking supernatant, add above-mentioned impregnation liquid, volatile oil, sucrose and potassium sorbate, add water adjustment total amount, Stir evenly, stand 24 hours, leaching supernatant, fill, obtain oral liquid.
Present invention additionally comprises aforementioned pharmaceutical compositions at preparation treatment insufficiency of kidney-YANG and QI and blood deficiency medicine In application.
This product carries out prescription according to traditional Chinese medicine theory.With Cornu Cervi Pantotrichum, Bombycis mori, excessive sheep in side Leaves of pulse plants warming the kidney to invigorate YANG is monarch drug.It is aided with Semen Allii Tuberosi, Radix Morindae Officinalis, Herba Cistanches, Semen Cuscutae, the Cortex Eucommiae, Radix Dipsaci Etc. product warm in nature, strengthen the merit of monarch drug warming the kidney to invigorate YANG;And with Cortex Cinnamomi warming YANG warming the kidney, it is intended that Ming Menwei Micro-ignition, to inspire kidney qi;Testis et Pentis Canis, Gecko are the product having essence for flesh and blood, integration of edible and medicinal herbs, to fill up Kidney water, i.e. enriches blood with blood, mends essence with essence;Again with Radix Ginseng, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Fructus Alpiniae Oxyphyllae, the big benefit of Rhizoma Dioscoreae Vigour, tonifying YANG consolidates spleen invigorating, needle warming moxibustion and mend the foundation of acquired constitution, makes the congenital foundation be conserved, with On be ministerial drug altogether.Help with Fructus Lycii, Rhizoma Polygonati, Radix Polygoni Multiflori Preparata, Fructus Ligustri Lucidi, Radix Rehmanniae Preparata tonification essence and blood, This is " kind YANG invigorating person, must in treating YANG within YIN, the most positive cloudy the helping and biochemical infinite ".Radix Linderae the kidney warming dissipates Cold, circulation of qi promoting of dispeling the wind, make righting not stay heresy;Poria spleen invigorating eliminating dampness by diuresis, makes benefit essence astringent or styptic treatment for spontaneous sweating and does not stay turbid damp. Radix Glycyrrhizae invigorating the spleen and benefiting QI, coordinating the actions of various ingredients in a prescription, for making medicine.
In sum, above all medicines share, and have warming the kidney to invigorate YANG, QI invigorating hemorrhage, effect of strengthening the tendons and bones. Be applicable to the aching pain in waist and back that kidney yang and QI and blood deficiency are caused, sexual impotence of passing out semen, night many urine, aversion to cold and cold limbs, The diseases such as loose stool, has a dizzy spell, cardiopalmus, insomnia have obvious curative effects.
Cornu Cervi Pantotrichum, has androgen-like action, promotes protein synthesis, leukocyte increasing, can improve uterus Tension force and its rhythm and pace of moving things of enhancing shrink, and strengthen cardiac contractile force, enhancing development, promote trauma fracture And ulcer healing, improve sugar and the energy metabolism of tricarboxylic acid cycle.
Bombycis mori, invigorating the liver and kidney, strong waist benefit essence, irritability function.
Herba Epimedii, Canis familiaris L. is had promotion to respect work secretory action by fluid extract, and can increase weight mouse prostate, lifting anus Flesh, it has Andrin-like action.Can promote that gonad is secreted, mice is tolerated the protected effect of anoxia, Epimedium brevicornum polysaccharide is promoted that mice T and β cell 3H-TdR mixes and the research of inducement interferon effect Showing, it is effective interferon inducer.Additionally Herba Epimedii can strengthen immunologic function, increases crown Arteries and veins flow, expands external perihaemal canal, increases acra flow, improves microcirculation and cardiotonic.
Semen Allii Tuberosi, invigorating the liver and kidney, strong waist knee joint, tonifying YANG controlling nocturnal emission with astringent drugs.
Radix Morindae Officinalis, energy kidney invigorating and YANG supporting, bone and muscle strengthening, scattered wind is dispeled cold.
Herba Cistanches, kidney-replenishing, benefiting essence-blood.
Semen Cuscutae, nourishing the liver and kidney, controlling nocturnal emission with astringent drugs reducing urination, antiabortive, improving eyesight.
The Cortex Eucommiae, nourishing the liver and kidney, benefiting essence-blood.
Radix Dipsaci, invigorating the liver and kidney, bone and muscle strengthening, continuous injured, only metrorrhagia.
Cortex Cinnamomi, energy kidney invigorating and YANG supporting, bone and muscle strengthening.
Testis et Pentis Canis, warming the kidney, tonifying YANG, benefit essence, benefit marrow.
Gecko, " book on Chinese herbal medicine is the newest " thinks that Gecko has " warming middle-JIAO kidney tonifying, controlling nocturnal emission with astringent drugs is supporing yang " to act on, modern Pharmacological research shows: Gecko has anti-stress effect, strengthens immunologic function, and has sex hormone function, makes Mouse prostate, seminal vesicle, levator ani muscle weight increase, and make mice pairing-season extend, ovary, uterus Loose.
Radix Ginseng, Radix Ginseng has excited and suppression dual function to central nervous system according to the literature, can increase Strong memory, has calm and stable effect, can strengthen hemopoietic function, strengthen cardiac contractile force, promote Endocrine gland is secreted, and increases protein synthesis, appetite stimulator, improves immunity of organisms, promotes gonad Secretion.
The Radix Astragali, the document report Radix Astragali has strong, blood pressure lowering, heart tonifying, diuresis and hormone-like effect, energy Extend rat rutting period, can enhancing human body immunity power, promote spleen antibody tormation, increase leukocyte, and Primary Human fetal glomerular mesangial cell, the life-span of primary golden hamster kidney cells can be extended.
The Rhizoma Atractylodis Macrocephalae, has a strong effect, Rhizoma Atractylodis Macrocephalae decoct gavage January, Mouse Weight can be promoted to increase and strengthen Swimming tolerance, can improve lymhocyte transformation rate and natural Flos Rosae Rugosae formation rate, promote cellular immunization Function, and substantially increase serum IgG, blood vessel function also expanded by the Rhizoma Atractylodis Macrocephalae in addition.
Fructus Alpiniae Oxyphyllae, nourishing the liver and kidney.
Rhizoma Dioscoreae, energy kidney invigorating and YANG supporting, bone and muscle strengthening.
Fructus Lycii, enhancing non-specific immunity effect, medlar oil can strengthen gulping down of mice chamber macrophage Bite ability;Oral Lycium Barbarum has promotion hemopoietic function, and glycine betaine has growth stimulation.
Rhizoma Polygonati, Rhizoma Polygonati decoct has the crown animal blood flow effect of increase, and energy blood fat reducing, disease-resistant former micro- The effects such as biology.
Radix Polygoni Multiflori, has an effect for reducing blood fat, enhancing body cold tolerance, to neurasthenia, and alopecia, Amyotrophy, the disease such as paraplegia has obvious effect, can promote lymphoblastic transformation.
Fructus Ligustri Lucidi, nourishing the liver and kidney, improving eyesight black hair.
Radix Rehmanniae, has an impact effect to cortex hormone function on kidney and hydrocortisone catabolism, heart is had enhancing Contractility effect.
The Radix Linderae, coclaurine has cardiotonic, and aconitine can expand blood vessel.
Poria, kidney-replenishing, benefiting essence-blood.
Radix Glycyrrhizae, pharmacology has 17-hydroxy-11-dehydrocorticosterone sample effect, improves immunologic function and Detoxication, and can town Cough and reduce phlegm, antitumor, blood fat reducing.
The most all medicines share, and play warming the kidney to activate YANG altogether, the merit of benefiting vital QI and blood, we be for insufficiency of kidney-YANG and Sore waist and aching in the waist and the back caused by QI and blood deficiency, aversion to cold and cold limbs, the diseases such as dizziness is weak, shortness of breath and palpitation.
Detailed description of the invention
With specific embodiment, the invention will be further described below, but the invention is not limited in these Embodiment.
Embodiment 1
Above 25-component, takes Bombycis mori, Gecko, Testis et Pentis Canis, Cornu Cervi Pantotrichum chopping, mixing, steams 30 points Clock, with the airtight dipping of Chinese liquor 700ml 15 days, filters, and filtrate is standby;Take Herba Epimedii, Radix Ginseng, Radix Morindae Officinalis, Semen Allii Tuberosi, Herba Cistanches, Semen Cuscutae, the Cortex Eucommiae, Radix Dipsaci are ground into coarse powder, use 65% second After alcohol impregnates 48 hours, carry out percolation with the speed of 2-3ml per minute, collect percolate 3680ml, Medicinal residues are standby;Take the Rhizoma Atractylodis Macrocephalae, Fructus Alpiniae Oxyphyllae, Cortex Cinnamomi powder are broken into coarse powder, extract volatile oil, the water after distillation The another device of solution preserves, and medicinal residues are standby;Merge above-mentioned medicinal residues, with 10 tastes such as remaining Rhizoma Polygonatis, add decocting Boiling secondary (10 times amount, 8 times amount), each 2 hours, collecting decoction, filtration, filtrate was with above-mentioned Aqueous solution after distillation merges, and being concentrated into relative density is 1.10 (70-80 DEG C), lets cool, adds ethanol Make alcohol content reach 65%, stir evenly, stand 24 hours, take supernatant and merge with above-mentioned percolate, decompression Reclaiming ethanol to relative density is 1.05 (70-80 DEG C), lets cool, stands 24 hours, filters, takes Supernatant, adds above-mentioned impregnation liquid, volatile oil the addition starch of conventional amount used, Pulvis Talci, stearic acid Magnesium adjuvant, routinely technique, make capsule, 0.5g/ grain.
Embodiment 2
Above 25-component, takes Bombycis mori, Gecko, Testis et Pentis Canis, Cornu Cervi Pantotrichum chopping, mixing, steams 30 points Clock, with the airtight dipping of Chinese liquor 700ml 15 days, filters, and filtrate is standby;Take Herba Epimedii, Radix Ginseng, Radix Morindae Officinalis, Semen Allii Tuberosi, Herba Cistanches, Semen Cuscutae, the Cortex Eucommiae, Radix Dipsaci are ground into coarse powder, use 65% second After alcohol impregnates 48 hours, carry out percolation with the speed of 2-3ml per minute, collect percolate 3680ml, Medicinal residues are standby;Take the Rhizoma Atractylodis Macrocephalae, Fructus Alpiniae Oxyphyllae, Cortex Cinnamomi powder are broken into coarse powder, extract volatile oil, the water after distillation The another device of solution preserves, and medicinal residues are standby;Merge above-mentioned medicinal residues, with 10 tastes such as remaining Rhizoma Polygonatis, add decocting Boiling secondary (10 times amount, 8 times amount), each 2 hours, collecting decoction, filtration, filtrate was with above-mentioned Aqueous solution after distillation merges, and being concentrated into relative density is 1.10 (70-80 DEG C), lets cool, adds ethanol Make alcohol content reach 65%, stir evenly, stand 24 hours, take supernatant and merge with above-mentioned percolate, decompression Reclaiming ethanol to relative density is 1.05 (70-80 DEG C), lets cool, stands 24 hours, filters, takes Supernatant, adds the cane sugar powder of above-mentioned impregnation liquid, volatile oil and conventional amount used, and technique is made routinely Granule.
Embodiment 3
Above 25-component, takes Bombycis mori, Gecko, Testis et Pentis Canis, Cornu Cervi Pantotrichum chopping, mixing, steams 30 points Clock, with the airtight dipping of Chinese liquor 700ml 15 days, filters, and filtrate is standby;Take Herba Epimedii, Radix Ginseng, Radix Morindae Officinalis, Semen Allii Tuberosi, Herba Cistanches, Semen Cuscutae, the Cortex Eucommiae, Radix Dipsaci are ground into coarse powder, use 65% second After alcohol impregnates 48 hours, carry out percolation with the speed of 2-3ml per minute, collect percolate 3680ml, Medicinal residues are standby;Take the Rhizoma Atractylodis Macrocephalae, Fructus Alpiniae Oxyphyllae, Cortex Cinnamomi powder are broken into coarse powder, extract volatile oil, the water after distillation The another device of solution preserves, and medicinal residues are standby;Merge above-mentioned medicinal residues, with 10 tastes such as remaining Rhizoma Polygonatis, add decocting Boiling secondary (10 times amount, 8 times amount), each 2 hours, collecting decoction, filtration, filtrate was with above-mentioned Aqueous solution after distillation merges, and being concentrated into relative density is 1.10 (70-80 DEG C), lets cool, adds ethanol Make alcohol content reach 65%, stir evenly, stand 24 hours, take supernatant and merge with above-mentioned percolate, decompression Reclaiming ethanol to relative density is 1.05 (70-80 DEG C), lets cool, stands 24 hours, filters, takes Supernatant, adds above-mentioned impregnation liquid, volatile oil, sucrose 200g and potassium sorbate 3g, and add water adjustment Total amount, to 1000ml, stirs evenly, and stands 24 hours, leaching supernatant, and fill obtains oral liquid.
Experimental example: the embodiment of the present invention 3 treats insufficiency of kidney-YANG and QI and blood deficiency clinical observation on the therapeutic effect:
Clinical data: treatment group and matched group totally 180 example, attached institute of Colleges Of Traditional Chinese Medicine Of Guangxi one, two attached institutes With 60 examples are respectively observed by Guangxi District the People's Hospital.
One, physical data:
Included in the object of observation is age 18-65 year, various chronic diseases cause, Chinese medical discrimination Belong to syndrome of deficiency of kidney-YANG or deficiency of both QI and blood patient.Treatment group 120 example, it is oral that use embodiment 3 obtains Liquid.Matched group 60 example, uses the YANSHENG HUBAO YE (insufficiency of kidney-YANG that Shenyang flying dragon health product group produces Card) and the ginseng stilbene royal jelly of The No.2 Pharmaceutical Factory, Yanji City of Jilin Province production nourish blood extract oral liquid (QI and blood deficiency Card).Two groups of sexes, age distribution are all shown in Table 1 without significant difference (P > 0.05).
Two, tcm diagnosis standard:
1, syndrome of deficiency of kidney-YANG: aching pain in waist and back, pass out semen sexual impotence, night many urine, pale complexion, fear of cold limb Cold, watery diarrhea with indigested food or Diarrhoea, pale tongue is fat indentation, and tongue is white, deep-slow pulse.
2, deficiency of both QI and blood: deficiency of QI with disinclination to talk, weak spontaneous perspiration, pale complexion, palpitation and insomnia, dizzy Dizzy, pale tongue with white fur, thready and rapid pulse.
Observational technique:
Observe 180 examples altogether, be randomly divided into 2 groups.Wherein treatment group 120 example, uses embodiment 3 to obtain The oral liquid arrived, each 15mL, take day 3 times, serve on 4 weeks.Matched group 60 example, syndrome of deficiency of kidney-YANG Person uses the YANSHENG HUBAO YE that Shenyang flying dragon health product group produces, each 20mL, every day 1 time, connects Take 4 weeks;The ginseng stilbene royal jelly that deficiency of both QI and blood person uses The No.2 Pharmaceutical Factory, Yanji City of Jilin Province to produce nourishes blood essence Oral liquid, each 10mL, every day 1 time, it serve on 4 weeks;Before test, experimenter is made detailed body by routine Lattice check, meet case selection standard person and can include the object of observation in.Weekly with examining 1 time after test, Inquire situation of taking medicine, the record state of an illness and side effect.Therapeutic effect scoring method is evaluated.Outcome measure is straight Connect and made by observer.Without other similar medicine during observation.
Result:
One, efficacy assessment standard:
1, curing in the recent period: primary symptom disappears, witness integration reduces more than 91%.
2, effective: primary symptom is clearly better (degree improves 2 grades), witness integration reduces 61-90%.
3, effective: primary symptom takes a turn for the better (degree improves 1 grade), witness integration reduces 31-60%.
4, invalid: primary symptom is without improving, and witness integration reduces less than 30%.
Two, therapeutic outcome:
1, compare before and after the treatment of syndrome of deficiency of kidney-YANG witness integration: be shown in Table 2.Treatment group as can be seen from Table 2 with After matched group patient treatment, each witness integration declines equal highly significant (P < 0.01), points out two groups of medicines To the sore waist and aching in the waist and the back caused by insufficiency of kidney-YANG and QI and blood deficiency, aversion to cold and cold limbs, dizziness is weak, shortness of breath and palpitation All improve significantly Deng disease.
2, compare before and after deficiency of both QI and blood witness integration and physico-chemical examination treatment: be shown in Table 3.
3, treatment group and matched group comparitive study, be shown in Table 4.Treatment group 120 example, effective percentage is 95%. Matched group 60 example, total effective rate is 90%.Two groups of Different therapeutical effects are notable by Ridit analytic process inspection nothing Meaning (P > 0.05).
Side effect:
Treatment group 120 example, does not finds obvious bad reflection and toxic and side effects during observation.
Table 1: treatment group compares with matched group sex (example), age (X ± SD) distribution
Note: treatment group compares with matched group sex, age distribution, the equal > of P value 0.05.
Table 2: compare (X ± SD) before and after syndrome of deficiency of kidney-YANG witness integration
Note: compare before and after treatment, the equal < of P value 0.05.
Table 3: compare (X ± SD) before and after deficiency of both QI and blood witness integration and physico-chemical examination treatment
Note: compare before and after treatment,**The equal < of P value 0.01.
Table 4: treatment group (A) and matched group (B) comparitive study (Ridit analysis)
Brief summary:
1, the oral liquid that embodiment 3 obtains has warming the kidney to activate YANG, and effect of benefiting vital QI and blood, to kidney yang Sore waist and aching in the waist and the back caused by deficiency and QI and blood deficiency, aversion to cold and cold limbs, the diseases such as dizziness is weak, shortness of breath and palpitation are equal There is therapeutical effect.
2, this organizes 120 examples, and total effective rate is 95%.Curative effect produces with Shenyang flying dragon health product group The ginseng stilbene royal jelly that YANSHENG HUBAO YE (syndrome of deficiency of kidney-YANG) and The No.2 Pharmaceutical Factory, Yanji City of Jilin Province produce nourishes blood essence Oral liquid (deficiency of both QI and blood) no significant difference.
3, this product is safe and reliable, without obvious adverse reaction and toxic and side effects.

Claims (3)

1. the pharmaceutical composition treating insufficiency of kidney-YANG and QI and blood deficiency, it is characterised in that: this medicine Compositions is made up of the crude drug of following weight parts:
Treatment insufficiency of kidney-YANG the most according to claim 1 and the pharmaceutical composition of QI and blood deficiency, It is characterized in that: this pharmaceutical composition is made up of the crude drug of following weight parts:
3. the pharmaceutical composition according to any one of claim 1-2 preparation treatment insufficiency of kidney-YANG and Application in the medicine of QI and blood deficiency.
CN201610315727.8A 2016-05-12 2016-05-12 Medicinal composition for treating kidney-yang insufficiency and qi-blood deficiency Pending CN105853867A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108452181A (en) * 2018-06-29 2018-08-28 芜湖张恒春药业有限公司 One kind controlling deficiency of the kidney herbal paste and preparation method thereof
CN112641870A (en) * 2021-01-14 2021-04-13 雷明 Medicine for treating male impotence and premature ejaculation

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CN1772120A (en) * 2005-10-22 2006-05-17 赵燕翼 Medicine composition
CN102008584A (en) * 2010-12-14 2011-04-13 句容市边城卫生院 Drug for treating kidney yang deficiency
CN104096094A (en) * 2014-04-21 2014-10-15 马家庆 Traditional Chinese medicine for treatment of abortion disease of pattern of dual vacuity of spleen and kidney
CN104288213A (en) * 2014-09-11 2015-01-21 广西百琪药业有限公司 Pharmaceutical composition for treating insufficiency of kidney-yang

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Publication number Priority date Publication date Assignee Title
CN1772120A (en) * 2005-10-22 2006-05-17 赵燕翼 Medicine composition
CN102008584A (en) * 2010-12-14 2011-04-13 句容市边城卫生院 Drug for treating kidney yang deficiency
CN104096094A (en) * 2014-04-21 2014-10-15 马家庆 Traditional Chinese medicine for treatment of abortion disease of pattern of dual vacuity of spleen and kidney
CN104288213A (en) * 2014-09-11 2015-01-21 广西百琪药业有限公司 Pharmaceutical composition for treating insufficiency of kidney-yang

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108452181A (en) * 2018-06-29 2018-08-28 芜湖张恒春药业有限公司 One kind controlling deficiency of the kidney herbal paste and preparation method thereof
CN112641870A (en) * 2021-01-14 2021-04-13 雷明 Medicine for treating male impotence and premature ejaculation

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