CN105853717A - Chinese patent medicine for treating type-II diabetes - Google Patents

Chinese patent medicine for treating type-II diabetes Download PDF

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Publication number
CN105853717A
CN105853717A CN201610204558.0A CN201610204558A CN105853717A CN 105853717 A CN105853717 A CN 105853717A CN 201610204558 A CN201610204558 A CN 201610204558A CN 105853717 A CN105853717 A CN 105853717A
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chinese patent
grams
rhizoma
medicine
powder
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CN201610204558.0A
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Chinese (zh)
Inventor
沈杰
吴建东
张璠
居群
张克勤
魏毅
陈剑云
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SHANGHAI YUSHENGTANG TECHNOLOGY Co Ltd
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SHANGHAI YUSHENGTANG TECHNOLOGY Co Ltd
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Priority to CN201610204558.0A priority Critical patent/CN105853717A/en
Publication of CN105853717A publication Critical patent/CN105853717A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/074Ganoderma
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/062Ascomycota
    • A61K36/066Clavicipitaceae
    • A61K36/068Cordyceps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8964Anemarrhena
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968Ophiopogon (Lilyturf)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969Polygonatum (Solomon's seal)

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mycology (AREA)
  • Medical Informatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention relates to the field of Chinese patent medicines and particularly relates to a Chinese patent medicine for treating type-II diabetes. The Chinese patent medicine is prepared from the following raw materials: 10-15g of sporoderm-broken ganoderma lucidum spore powder, 5-8g of paecilomyces hepialid powder, 8-10g of rhizoma polygonati, 3-5g of Chinese yam, 1-3g of rhizoma anemarrhenae, 1-3g of radix polygonati officinalis, 1-3g of radix ophiopogonis and 3-5g of liquorice. In the invention, the adopted Chinese herbal medicines conform to the regulations of the Pharmacopoeia of the People's Republic of China, and the medicine is safe and reliable and has the effects of improving blood circulation of pancreas, enhancing the physiological functions of pancreas, reducing the blood glucose and the like. The product compatibility is based on the yin-yang qi-blood balance theory of the traditional Chinese medicine; and the Chinese patent medicine has the characteristics of reliable curative effect, high effect taking speed, no side effect and the like for patients suffering thirst and polydipsia and qi-yin deficiency caused by the type-II diabetes.

Description

One is used for treatingⅡThe Chinese patent medicine of patients with type Ⅰ DM
Technical field
The present invention relates to technical field of Chinese patent medicine, a kind of Chinese patent medicine for treating type Ⅱdiabetes mellitus.
Background technology
Along with the impact of bad life style, diabetes are the most no longer the patents of old people.Diabetes patient's age is in the trend of declining to a great extent at present, even has the child morbidity of about 10 years old.In clinic, new patients with NIDDM of sending out gets more and more, and the age is many to be substantially increased than several years ago at 25 ~ 30 years old, and 60% is overweight or obesity.Long-term hyperphagia, absorbs high heat, and body weight is gradually increased, so that fat, cause insulin resistant after obesity, blood glucose raises, without obvious Ketosis-prone.
Diabetes are broadly divided into 1 type and type Ⅱdiabetes mellitus.It is main and (or) with hypoinsulinism, most a kind of diseases can being effectively controlled by Diet Therapy, exercise therapy and related drugs that type Ⅱdiabetes mellitus refers to by insulin resistant, but it is sick to be the most medically also difficult to effect a radical cure this.Simultaneously because the various complication that diabetes may cause, bring a lot of misery can to the body and mind of people.In China, type Ⅱdiabetes mellitus people accounts for the 90% of diabetes sum.
At present diabetics is mainly based on western medical treatment or the way of the combination of Chinese and Western medicine.Chemicals oral medication or insulin injection therapy is substantially used to realize controlling blood glucose.General oral class has the medicines such as sulphanylureas, biguanides, meglitinide, also has injection of insulin therapy.Western medical treatment is while relief of symptoms, it has been found that more weak in terms of improving pancreas physiological vigor, some patients is carried out in western modern medicine treatment for a long time; Drug resistance is caused to strengthen; pancreas, liver, compromised kidneys, go down with Liver and kidney function, causes the crisis of the various complication of diabetes.
Summary of the invention
It is an object of the invention to provide a kind of Chinese patent medicine for treating type Ⅱdiabetes mellitus, it solves the related drugs side effect technical problem occurred in the treatment of above-mentioned existing main western modern medicine, has that curative effect is reliable, instant effect, the feature such as have no side effect.
For solving above-mentioned technical problem, the present invention is achieved in that
A kind of Chinese patent medicine for treating type Ⅱdiabetes mellitus, it is characterized in that: it is made up of following raw material: Ganoderma spore powder with cellular wall broken 10 ~ 15 grams, 5 ~ 8 grams of peacilomyce hepiahi bacterium powder, Rhizoma Polygonati 8 ~ 10 grams, Rhizoma Dioscoreae 3 ~ 5 grams, the Rhizoma Anemarrhenae 1 ~ 3 gram, Rhizoma Polygonati Odorati 1 ~ 3 gram, Radix Ophiopogonis 1 ~ 3 gram, 3 ~ 5 grams of Radix Glycyrrhizae.
The described Chinese patent medicine for treating type Ⅱdiabetes mellitus, it is characterized in that: its preparation method is, in proportion Rhizoma Polygonati, Rhizoma Dioscoreae, the Rhizoma Anemarrhenae, Rhizoma Polygonati Odorati, Radix Ophiopogonis, Radix Glycyrrhizae will be mixed with Ganoderma spore powder with cellular wall broken, peacilomyce hepiahi bacterium powder, and use the comminution by gas stream dry technology of advanced person, compound is crushed to 44 μm (325 mesh) below, and forms powder.
Detailed description of the invention
It is further described the present invention below in conjunction with embodiment.
Embodiment 1
Raw material: Ganoderma spore powder with cellular wall broken 15 grams, 7 grams of peacilomyce hepiahi bacterium powder, Rhizoma Polygonati 8 grams, Rhizoma Dioscoreae 3 grams, the Rhizoma Anemarrhenae 2 grams, Rhizoma Polygonati Odorati 2 grams, Radix Ophiopogonis 2 grams, 5 grams of Radix Glycyrrhizae.
In proportion Rhizoma Polygonati, Rhizoma Dioscoreae, the Rhizoma Anemarrhenae, Rhizoma Polygonati Odorati, Radix Ophiopogonis, Radix Glycyrrhizae are mixed with Ganoderma spore powder with cellular wall broken, peacilomyce hepiahi bacterium powder, and use the comminution by gas stream dry technology of advanced person, compound is crushed to 44 μm (325 mesh) below, and forms powder.
Case 1: Wang, 32 years old, health check-up in 2013 detection fasting glucose 8.1 mM/ls and after the meal two hours blood glucose 12 mM/ls, build was micro-fat, thirsty weak, and slight abnormal carbohydrate metabolism is diagnosed as patients with NIDDM.Use the present embodiment 1 oral Chinese patent medicine powder three times on the one on an empty stomach, after adding motion one week, liver,spleen,kidney, pancreas blood circulation improve, particularly pancreas physiological vigor strengthens, body self-repairing capability, insulin metabolism ability improve, after one week, blood sugar recovery normal level, thirsty weak is improved.Glucostasis after two weeks.After 1 month, pancreas metabolism recovers normal, with consolidating again one month, thoroughly fully recovers, so far no recurrence.
Embodiment 2
Raw material: Ganoderma spore powder with cellular wall broken 15 grams, 8 grams of peacilomyce hepiahi bacterium powder, Rhizoma Polygonati 10 grams, Rhizoma Dioscoreae 3 grams, the Rhizoma Anemarrhenae 2 grams, Rhizoma Polygonati Odorati 2 grams, Radix Ophiopogonis 2 grams, 3 grams of Radix Glycyrrhizae.
In proportion Rhizoma Polygonati, Rhizoma Dioscoreae, the Rhizoma Anemarrhenae, Rhizoma Polygonati Odorati, Radix Ophiopogonis, Radix Glycyrrhizae are mixed with Ganoderma spore powder with cellular wall broken, peacilomyce hepiahi bacterium powder, and use the comminution by gas stream dry technology of advanced person, compound is crushed to 44 μm (325 mesh) below, and forms powder.
Case 2: Mr. Sun, 36 years old, patients with NIDDM, before 2 years, oneself managed a small enterprise, and dinner party is many, and tobacco and wine are continuous, often stay up late or eat and drink extravagantly, myasthenia of limbs occur, and unstable blood pressure is fixed, dry mouth and tougue, polyuria, and repeated detection fasting glucose is more than or equal to 7.Use the present embodiment 2 on an empty stomach oral Chinese patent medicine powder three times on the one, after adding motion one week, mainly caused the symptoms such as fixed, the hypoinsulinism of unstable blood pressure to be controlled by operating pressure, the factor such as nervous.Having consolidated again two weeks, in addition reasonably work and rest, unfolded mood rightly and alleviate pressure, be aided with example 2 oral Chinese patent medicine powder on an empty stomach, pancreas vigor strengthens, glucostasis, so far no recurrence.
Embodiment 3
Raw material: Ganoderma spore powder with cellular wall broken 15 grams, 8 grams of peacilomyce hepiahi bacterium powder, Rhizoma Polygonati 10 grams, Rhizoma Dioscoreae 3 grams, the Rhizoma Anemarrhenae 3 grams, Rhizoma Polygonati Odorati 3 grams, Radix Ophiopogonis 3 grams, 5 grams of Radix Glycyrrhizae.
In proportion Rhizoma Polygonati, Rhizoma Dioscoreae, the Rhizoma Anemarrhenae, Rhizoma Polygonati Odorati, Radix Ophiopogonis, Radix Glycyrrhizae are mixed with Ganoderma spore powder with cellular wall broken, peacilomyce hepiahi bacterium powder, and use the comminution by gas stream dry technology of advanced person, compound is crushed to 44 μm (325 mesh) below, and forms powder.
Case 3: Zhang Mounv, 38 years old, being diagnosed as type Ⅱdiabetes mellitus had the time more than 2 years, makes insoral to alleviate pathoglycemia for a long time.More than 2 years, drug dependence strengthens, and goes down with hepatic and renal function, the side effect such as immunity degradation.Use the present embodiment 3 oral Chinese patent medicine powder three times on the one on an empty stomach, after adding aerobatic exercise one week, dependency for biguanides reduces, the internal organs vigor such as liver, kidney, pancreas strengthen, immunity steps up, and has consolidated again two weeks, can be replaced doctor trained in Western medicine antidiabetic drug by example 3 oral Chinese patent medicine powder on an empty stomach, glucostasis, so far no recurrence.
The pharmacology analysis of product of the present invention:
1, Ganoderma spore powder with cellular wall broken: containing compositions such as abundant Ganoderma triterpenoids, ganoderan, organic germanium, organic selenium, adenosine, polypeptide.For diabetic patients, nutrient substance is made to enter cell, and it is external to make bodily waste get rid of, improve liver, kidney, pancreas vigor, be conducive to controlling the secretion of blood sugar insulin, it is provided that constant energy, have and improve pancreas blood circulation, improve pancreas physiological function, reduce blood glucose, improve spiritlessness and weakness, uncomfortable in chest the effect such as suppress.
2, peacilomyce hepiahi bacterium powder: containing compositions such as abundant Cordycepin, cordycepic acid, adenosine and polysaccharide.The regulation effect that hormonal system and the nervous system of human body have been had;Cordycepic acid can change microcirculation in human body, has obvious blood fat reducing and hypoglycemic activity;Cordyceps polysaccharide is immunomodulator, can enhancing body to viral resistance.
3, Rhizoma Polygonati: for deficiency of spleen-QI and stomach-QI, fatigue and asthenia, deficiency of stomach-Yin, xerostomia lack of appetite, deficiency of the lung cough caused by dryness, chronic cough hemoptysis, asthenia of essence and blood, soreness of the waist and knees, early whitening of beard and hair, interior-heat is quenched one's thirst.
4, Rhizoma Dioscoreae: have nourishing strong, aid digestion, hold back sweating due to debility, effect of antidiarrheal, cure mainly insufficiency of the spleen diarrhoea, cough due to deficiency of the lung, diabetes are quenched one's thirst, oliguria frequency, seminal emission, women's leukorrhagia and dyspeptic chronic enteritis.
5, the Rhizoma Anemarrhenae: calentura excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat quenches one's thirst, dryness of the intestine constipation.
6, Rhizoma Polygonati Odorati: nourishing YIN to relieve dryness, effect of promoting the production of body fluid to quench thirst.Being usually used in lung stomach-Yin wound, cough caused by dryness-heat, dry throat and mouth, interior-heat is quenched one's thirst.
7, Radix Ophiopogonis: YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.For dryness of the lung dry cough, deficiency of YIN consumptive disease is coughed, sore throat pharyngalgia, and Tianjin wound is thirsty, and interior-heat is quenched one's thirst, vexed insomnia, dryness of the intestine constipation.
8, Radix Glycyrrhizae: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.
It is an advantage of the current invention that the Chinese herbal medicine that invention is used meets Pharmacopoeia of People's Republic of China regulation, safety of medicine is reliable, and particularly on medical material is chosen, selecting the freezing wall breaking technology crystallization Ganoderma spore powder with cellular wall broken in modern biotechnology medicine is monarch drug;The Cordyceps Paecilomyces hepiali mycopowder selecting mass component stable is ministerial drug;Rhizoma Polygonati, Rhizoma Dioscoreae, the Rhizoma Anemarrhenae, Rhizoma Polygonati Odorati, Radix Ophiopogonis are supplementary drug, Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, according to Chinese medicine Neo-Confucianism monarch, four-quadrant equilibrium principle, absorption be used as medicine after are effectively ensured ageing with treatment.
For type Ⅱdiabetes mellitus high blood glucose, thirsty polydipsia, syndrome of deficiency of both qi and yin person, there is following functions: improve pancreas blood circulation, improve pancreas physiological function, reduce the effects such as blood glucose.Curative effect is reliable, instant effect, have no side effect.
Using advanced comminution by gas stream dry technology, 44 μm (325 mesh) below, can realize efficient absorption.
It is only presently preferred embodiments of the present invention in sum, is not used for limiting the practical range of the present invention.The most all equivalence changes made according to the content of scope of the present invention patent and modification, all should be the technology category of the present invention.

Claims (2)

1. the Chinese patent medicine being used for treating type Ⅱdiabetes mellitus, it is characterized in that: it is made up of following raw material: Ganoderma spore powder with cellular wall broken 10 ~ 15 grams, 5 ~ 8 grams of peacilomyce hepiahi bacterium powder, Rhizoma Polygonati 8 ~ 10 grams, Rhizoma Dioscoreae 3 ~ 5 grams, the Rhizoma Anemarrhenae 1 ~ 3 gram, Rhizoma Polygonati Odorati 1 ~ 3 gram, Radix Ophiopogonis 1 ~ 3 gram, 3 ~ 5 grams of Radix Glycyrrhizae.
Chinese patent medicine for treating type Ⅱdiabetes mellitus the most according to claim 1, it is characterized in that: in proportion by Rhizoma Polygonati, Rhizoma Dioscoreae, the Rhizoma Anemarrhenae, Rhizoma Polygonati Odorati, Radix Ophiopogonis, Radix Glycyrrhizae, mix with Ganoderma spore powder with cellular wall broken, peacilomyce hepiahi bacterium powder, and use the comminution by gas stream dry technology of advanced person, compound is crushed to 44 μm (325 mesh) below, and forms powder.
CN201610204558.0A 2016-04-05 2016-04-05 Chinese patent medicine for treating type-II diabetes Pending CN105853717A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109568489A (en) * 2018-12-18 2019-04-05 漳州市吾梓贸易有限公司 A kind of Chinese medicine composition and preparation method thereof for treating diabetes

Citations (3)

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Publication number Priority date Publication date Assignee Title
CN102308990A (en) * 2011-07-19 2012-01-11 南宁大单生物科技有限责任公司 Bitter gourd and Chinese caterpillar fungus and ganoderma lucidum powder
CN102379908A (en) * 2011-11-11 2012-03-21 全国供销合作总社济南果蔬华德公司 Wall breaking method for fresh and live ganoderma lucidum spores
CN104906145A (en) * 2015-05-28 2015-09-16 吉林大学 Medical application of paecilomyces hepiali mutant strain PH40 in treating diabetes

Patent Citations (3)

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Publication number Priority date Publication date Assignee Title
CN102308990A (en) * 2011-07-19 2012-01-11 南宁大单生物科技有限责任公司 Bitter gourd and Chinese caterpillar fungus and ganoderma lucidum powder
CN102379908A (en) * 2011-11-11 2012-03-21 全国供销合作总社济南果蔬华德公司 Wall breaking method for fresh and live ganoderma lucidum spores
CN104906145A (en) * 2015-05-28 2015-09-16 吉林大学 Medical application of paecilomyces hepiali mutant strain PH40 in treating diabetes

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109568489A (en) * 2018-12-18 2019-04-05 漳州市吾梓贸易有限公司 A kind of Chinese medicine composition and preparation method thereof for treating diabetes

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