CN105842267A - Non-synchrotron radiation micro-X-ray fluorescence CT imaging system and method - Google Patents
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Abstract
The invention discloses an X-ray fluorescence CT imaging system which comprises an X-ray source, a multi-capillary focus lens, two X-ray intensity detectors, a sample control bench, a fluorescence detector and a data processing system. X-ray light emitted from the X-ray source is focused into a micro-beam parallel light through the multi-capillary focus lens and irradiates a to-be-tested sample. The to-be-tested sample is translated and is rotated by means of the sample control bench. The X-ray light and substances in the to-be-tested sample have interaction to generate fluorescence. The fluorescence detector detects the X-ray fluorescence. The data processing system analyzes and processes an X-ray fluorescence spectrum obtained from the fluorescence detector to obtain projection data of X-ray fluorescence CT. Intensities of incident and exit X-rays, which are recorded by the X-ray intensity detector, are calculated to obtain transmission CT projection data. The distribution and content of elements in the sample is re-established through the transmission CT projection data and X-ray fluorescence CT projection data.
Description
Technical field
The present invention relates to a kind of x-ray imaging method, particularly to a kind of asynchronous radiation micro-beam X-ray fluorescence CT side
Method.
Background technology
XRF computer tomography (CT) method is X ray CT and two kinds of organic knots of technology of x-ray fluorescence analysis
The product closed, it, should by measuring characteristic x-ray fluorescence and then reconstructing the non radioactive element distributed image in sample interior
Method is a kind of Dynamic Non-Destruction Measurement, can simultaneously in measuring samples multiple element distribution carry out at destructiveness without to sample
Reason.Major experimental equipment is as it is shown in figure 1, mainly include monochromator 13,14, two X-ray intensity detectors 5 of beam limiting device, glimmering
Photo-detector 7, sample stage 6 and data handling system.
In traditional XRF CT method, synchrotron radiation light source 12 obtains list through monochromator 13 and beam limiting device 14
The X-ray microbeam 15 of color, microbeam 15 is irradiated on sample 6, the XRF that during microbeam irradiation, sample 6 is inspired
By 7 records of fluorescent probe, then according in Fig. 1 direction shown in arrow 4 translation sample be scanned, after the end of scan according to
Rotary sample 6 at an angle, direction shown in arrow 8, then repeat translation scan process, until on whole 360 ° of circumference
Scan one time；So obtain one group of fluorescence spectroscopy 8, obtain the fluorescence intensity data i.e. X of one group of certain element by solving X-ray energy spectrum
Data for projection 9 computer 10 of ray fluorescence CT just can go out the two dimension unit about detection plane according to the program restructuring designed
The gray value of element distributed image 11(image is corresponding with concentration of element distribution).
In traditional XRF CT, the x-ray source used is synchrotron radiation light source 12, because synchrotron radiation source sets
Standby expensive and the hugest irremovable, carry out in site measurement with it and do not meet reality, which limits the wide of the method
General application；It addition, in Traditional x-ray fluorescence CT, the X-ray focusing of use, collimating optics in monochromator 13 and beam limiting device 14
Device there is also the drawbacks such as X-ray energy loss is big, focus energy is single.
Conduit X-ray optics and polycapillary optic that the nineties in 20 century grows up achieve high-power
The regulation and control of broadband X-ray.Nowadays, capillary tube focusing technology also has been used for the focusing in fluorescence microanalysis to x-ray source, in detail
Refer to document: Li Fangzuo, Liu Zhiguo, Sun Tianxi, etc. capillary X-ray lens three-dimensional copolymerization Jiao's microbeam X ray fluorescence technology
Application [J] in rock salt sample is analyzed. spectroscopy and spectrum analysis, 2015 (9).
Summary of the invention
The technical problem to be solved in the present invention is that proposition is a kind of based on capillary tube focusing technology, asynchronous radiation X ray
Source fluorescence CT imaging system and method, to realize constituent content in biological tissue samples and the in site measurement of distribution.
The technical solution adopted in the present invention is as follows:
A kind of based on capillary tube focusing, asynchronous radiation X ray source fluorescence CT imaging system, gather including x-ray source, multiple capillary
Focus lens, two X-ray intensity detectors, sample control station, fluorescent probe and data handling system.Send out at x-ray source
Multiple capillary condenser lens and two X-ray intensity detectors, two X-ray intensity detectors are set in the X-ray light path gone out
Between be sample control station, sample control station is placed sample, and the X-ray light that sends of X-ray tube source gathers through multiple capillary
Focus lens is focused into microbeam directional light, is irradiated to detected sample, controls detected sample by sample control station and translates and turn
Dynamic, X-ray light and the matter interaction in detected sample and produce fluorescence；Fluorescent probe is arranged on detected sample
Lower section, is perpendicular to incident X-rays direction, utilizes fluorescent probe to detect described XRF；Fluorescent probe and X
Transmitted intensity detector is connected with data handling system signal, the XRF that fluorescent probe is recorded by data handling system
Spectrum obtains the data for projection of XRF CT through analyzing and processing, X-ray intensity detector record is incident, exit Xray
Intensity carries out being calculated transmission CT projection data, then by transmission CT projection data and XRF CT data for projection pair
In described sample, Elemental redistribution and content are rebuild.
Present invention further propose that employing system above carries out fluorescence CT formation method, including:
(1) the X-ray light sent by x-ray source is focused into microbeam directional light through multiple capillary condenser lens, is irradiated to tested
Test sample product, produce fluorescence by the matter interaction in the translation of detected sample and rotation, X-ray light and detected sample；
(2) utilizing fluorescent probe to detect described XRF, fluorescent probe is perpendicular to incident X-rays direction, right
All fluorescence in a certain region detect, and obtain X-ray fluorescence spectra data；
(3) it is analyzed described X-ray fluorescence spectra processing the data for projection obtaining XRF CT；
(4) utilize the incidence of X-ray intensity detector record, the intensity of exit Xray, and calculate the transmission CT of described sample
Data for projection；The data for projection of described transmission CT also includes each fluorescent energy section CT data for projection, calculate strength retrogression's coefficient with
Fluorescent X-ray absorptance is used for Elemental redistribution and the reconstruct of content.
(5) according to described transmission CT projection data and XRF CT data for projection to element in described sample
Distribution is rebuild；
Wherein, described x-ray source can use common x-ray source, its pipe pressure, pipe flow all scalable.Described multiple capillary focuses on
Use capillary X-ray lens, can be one or more.
Described translation is along being perpendicular to detection plane and incident X-rays direction by incident micro-beam X-ray width by described sample
Spend equidistant movement, until scanning through whole detection plane.Described rotation is to be revolved around the axle being perpendicular to test surface by described sample
Turn, rotate equal angular (such as 1 °) every time, until scanning one time on whole 360 ° of circumference.
Advantages of the present invention is as follows: replace huge synchrotron radiation source with common X-ray tube source and imaging system is able to
Simplify, make in situ detection be possibly realized.Use multi-capillary X-ray condenser lens to replace monochromator and beam limiting device to make simultaneously
Imaging system structure further simplifies and imaging arrangement is more stable；The use of multi-capillary X-ray condenser lens also pole
The earth reduces the loss of x-ray source energy；The spatial resolution of the element distribution image reconstructed is focused on thoroughly by multiple capillary
Microbeam speckle size after mirror focuses on is determined.
Accompanying drawing explanation
Fig. 1 is the structured flowchart of Traditional x-ray fluorescence CT imaging system；
Fig. 2 is the structured flowchart based on multiple capillary condenser lens micro-beam X-ray fluorescence CT imaging system of the present invention.
Detailed description of the invention
2 detailed description of the invention providing the present invention below in conjunction with the accompanying drawings.
The present invention uses system as shown in Figure 2, specifically uses X-ray tube including x-ray source 1(), multiple capillary focuses on
2, two X-ray intensity detectors 5 of lens, sample control station 6, fluorescent probe 7 and data handling system.
The micro-beam X-ray fluorescence CT method operation principle of the present invention is as follows:
It is direct that the polychrome large spot that the X-ray that X-ray tube source 1 sends is formed is focused into microbeam through multiple capillary condenser lens 2
Being irradiated on sample 6 ＇, inspire the characteristic x-ray fluorescence within sample 6 ＇, above-mentioned fluorescence is by 7 records of fluorescent probe, logical
Cross translation, rotary sample can be obtained by one group of X-ray fluorescence spectra 8, can obtain by resolving X-ray fluorescence spectra data
One group of fluorescence intensity data, i.e. XRF CT data for projection 9.Utilize computer 10 to use the algorithm designed, import and throw
The gray value that shadow data can reconstruct the two-dimensional element distributed image 11(image of institute's detection plane is relative with concentration of element distribution
Should).
The method for reconstructing that the present invention takes refers to document Hogan, J. P., et al. (1991). "
Fluorescent computer tomography: a model for correction of X-ray absorption."
Nuclear Science, IEEE Transactions on 38(6): 1721-1727.
The microbeam fluorescence CT method primary operational that the present invention takes includes:
(1) heterogeneous x ray sent by x-ray source 1 is focused into polychrome micro-beam X-ray through multiple capillary condenser lens 2 and is radiated at
On sample 6 ＇, direction as shown in Fig. 24, sample is along being perpendicular to detection plane and incident X-rays direction by incident micro-beam X-ray
The equidistant movement of width, until the direction is completely scanned, then by sample direction as shown in Fig. 23, sample is around being perpendicular to spy
The axle in survey face rotates an angle, such as 1 °, then repeats said process until completing 360 ° of range scans.
(2) utilize XRF detector 7 to gather above-mentioned XRF, obtain one group of X-ray fluorescence spectra data 8.
(3) above-mentioned X-ray fluorescence spectra data are resolved, extract the fluorescence intensity data i.e. fluorescence of one group of certain element
The data for projection 9a of CT；
(4) can be detected by X-ray intensity detector 5 through the X-ray intensity data that sample is forward and backward, through calculating i.e.
The data for projection 9b of available transmission CT；
(5) whole data for projection 9a and 9b are inputted computer 10, can try to achieve about detection now by the program designed
The distribution of two-dimensional element on face, element distribution image 11 resolution is determined by multiple capillary condenser lens.
Wherein, the microbeam after X-ray focusing should ensure that in translation motion sample is scanned just completely.
Wherein, in some cases, need to carry out Gamma spectrum analysis, at this moment also need to additionally measure each fluorescent energy section
Transmission projection data.
The invention provides the improvement project of a kind of experimental provision: owing to using common X-ray tube source so that X-ray is glimmering
Light CT carries out in situ detection and is possibly realized, and compared with Traditional x-ray fluorescence CT, imaging system structure has obtained greatly simplifying,
Constructing system cost also greatly reduces；Owing to using multiple capillary condenser lens replace the monochromator in conventional fluorescent CT and gather
Burnt and wire harness device makes imaging system simplify the most greatly reduction X-ray energy further and arrives the damage before sample
Consumption.
Claims (6)
1. based on capillary tube focusing, an asynchronous radiation X ray source fluorescence CT imaging system, including x-ray source (1), hirsutism
At tubule condenser lens (2), two X-ray intensity detectors (5), sample control station (6), fluorescent probe (7) and data
Reason system；It is characterized in that: in the X-ray light path that x-ray source (1) sends, be provided with multiple capillary condenser lens (2) and two X
Transmitted intensity detector (5), is sample control station (6) between two X-ray intensity detectors, and sample control station is placed sample
Product, and the X-ray light that x-ray source sends is focused into microbeam directional light through multiple capillary condenser lens, is irradiated to tested test sample
Product, control detected sample by sample control station and translate and rotate, X-ray light and the matter interaction in detected sample
And produce fluorescence；Fluorescent probe (7) is arranged on below detected sample, is perpendicular to incident X-rays direction, utilizes fluorescence detection
Described XRF is detected by device；Fluorescent probe and X-ray intensity detector are connected with data handling system signal,
The X-ray fluorescence spectra that fluorescent probe is recorded by data handling system obtains the projection number of XRF CT through analyzing and processing
According to, the intensity of the incidence of X-ray intensity detector record, exit Xray is carried out being calculated transmission CT projection data, then leads to
Cross transmission CT projection data and Elemental redistribution and content in described sample are rebuild by XRF CT data for projection.
The most according to claim 1 based on capillary tube focusing, asynchronous radiation X ray source fluorescence CT imaging system, it is special
Levying and be, described x-ray source uses pipe pressure, the most adjustable x-ray source of pipe flow.
The most according to claim 1 based on capillary tube focusing, asynchronous radiation X ray source fluorescence CT imaging system, it is special
Levying and be, described multiple capillary condenser lens uses capillary X-ray lens, can be one or more.
4. the method utilizing system described in claim 1-3 to carry out fluorescence CT imaging, comprises the following steps:
(1) the X-ray light sent by x-ray source is focused into microbeam directional light through multiple capillary condenser lens, is irradiated to tested
Test sample product, produce fluorescence by the matter interaction in the translation of detected sample and rotation, X-ray light and detected sample；
(2) utilizing fluorescent probe to detect XRF, described fluorescent probe is perpendicular to incident X-rays direction,
Obtain X-ray fluorescence spectra data；
(3) it is analyzed described X-ray fluorescence spectra processing the data for projection obtaining XRF CT；
(4) utilize the incidence of X-ray intensity detector record, the intensity of exit Xray, and calculate the transmission CT of described sample
Data for projection；
(5) according to described transmission CT projection data and XRF CT data for projection to Elemental redistribution in described sample and
Content is rebuild.
Fluorescence CT formation method the most according to claim 4, it is characterised in that described translation is along vertical by described sample
Pressing the incident equidistant movement of micro-beam X-ray width in detection plane and incident X-rays direction, putting down until scanning through whole detection
Face；Described rotation is to be rotated around the axle being perpendicular to test surface by described sample, rotates equal angular every time, until whole
Scan one time on 360 ° of circumference.
Fluorescence CT formation method the most according to claim 1, it is characterised in that described transmission CT projection data includes each glimmering
Light energy section CT data for projection, calculates strength retrogression's coefficient with fluorescent X-ray absorptance for Elemental redistribution and the weight of content
Structure.
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106248705A (en) * | 2016-09-09 | 2016-12-21 | 重庆大学 | A kind of formation method mixing XRF CT and X-ray acoustic CT and system |
| CN107315019A (en) * | 2017-07-25 | 2017-11-03 | 清华大学 | Transmission of radiation and fluorescence CT imaging systems and imaging method |
| CN107356414A (en) * | 2017-09-15 | 2017-11-17 | 江苏亨通光导新材料有限公司 | A kind of apparatus and method for testing optical fiber precast rod refractivity distribution |
| CN113358674A (en) * | 2021-04-01 | 2021-09-07 | 西安交通大学 | Neutron resonance CT imaging system and method designed for reinforced concrete member |
| CN116337912A (en) * | 2023-05-24 | 2023-06-27 | 苏州佳谱科技有限公司 | System and method for detecting element content in new energy battery material |
| CN116754431A (en) * | 2023-08-18 | 2023-09-15 | 中国工程物理研究院激光聚变研究中心 | Transient proton fluorescence detection system |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106248705A (en) * | 2016-09-09 | 2016-12-21 | 重庆大学 | A kind of formation method mixing XRF CT and X-ray acoustic CT and system |
| CN107315019A (en) * | 2017-07-25 | 2017-11-03 | 清华大学 | Transmission of radiation and fluorescence CT imaging systems and imaging method |
| CN107356414A (en) * | 2017-09-15 | 2017-11-17 | 江苏亨通光导新材料有限公司 | A kind of apparatus and method for testing optical fiber precast rod refractivity distribution |
| CN113358674A (en) * | 2021-04-01 | 2021-09-07 | 西安交通大学 | Neutron resonance CT imaging system and method designed for reinforced concrete member |
| CN113358674B (en) * | 2021-04-01 | 2024-05-24 | 西安交通大学 | Neutron resonance CT imaging system and method designed for reinforced concrete member |
| CN116337912A (en) * | 2023-05-24 | 2023-06-27 | 苏州佳谱科技有限公司 | System and method for detecting element content in new energy battery material |
| CN116754431A (en) * | 2023-08-18 | 2023-09-15 | 中国工程物理研究院激光聚变研究中心 | Transient proton fluorescence detection system |
| CN116754431B (en) * | 2023-08-18 | 2023-11-17 | 中国工程物理研究院激光聚变研究中心 | Transient proton fluorescence detection system |
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