CN105833148A - Traditional Chinese medicine composition with effects of improving memory, resisting arteriosclerosis, inhibiting thrombosis and improving immunity - Google Patents
Traditional Chinese medicine composition with effects of improving memory, resisting arteriosclerosis, inhibiting thrombosis and improving immunity Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine composition with the effects of improving memory, resisting arteriosclerosis, inhibiting thrombosis and improving immunity. The traditional Chinese medicine composition is prepared from, by weight, 3-6 parts of fructus alpiniae oxyphyllae, 9-15 parts of poria cocos, 10-30 parts of rhizoma polygonati and 5-10 parts of barbary wolfberry fruit. The traditional Chinese medicine composition has the effects of improving the memory, resisting the arteriosclerosis, inhibiting the thrombosis, improving the immunity, improving prostate symptoms, resisting fatigue, improving sleep, reducing blood fat and blood sugar level, resisting oxidation and cancers, beautifying the features, facilitating feces excretion, losing weight and the like.
Description
Technical field
The present invention relates to Chinese medicine composition, specifically, relate to one and improve memory, resist and move
Arteries and veins hardening, inhibition thrombosis, the integration of edible and medicinal herbs compositions of raising immunity.
Background technology
With regard to people all one's life for, functional activity experiencings evolution." Ling Shu Miraculous Pivot or Divine Axis natural life-span " is called:
" life ten years old, it is fixed that the five internal organs begin, and vim and vigour are the most logical, its gas under, therefore convenient for walking.20 years old, blood
Gas begins to contain, muscle side head, therefore becomes well.30 years old, the five internal organs were the most fixed, and muscle is firm, and blood vessels are contained
Full, therefore good step.40 years old, the vital organs of the human body twelve regular channels, the biggest Sheng is to calm down, and space between skin and muscles begins to dredge,
High honour ruined fall, send out frequency the most grizzled, flat Sheng is not shaken, therefore good sits.50 years old, irritability began to decline, lobe of the liver
Beginning thin, bile begins to go out, and mesh begins not clear.Threescore, the motive begins to decline, and bitter melancholy is sad, and vim and vigour are slack lazy,
Therefore it is good sleeping.70 years old, deficiency of spleen-QI, skin was withered.80 years old, lung qi declined, soul from, therefore speech is kind
By mistake.90 years old, kidney qi was burnt, and four dirty passages through which vital energy circulates are hollow.At the age of one hundred years old, the five internal organs are the most empty, and manner is all gone,
Human skeleton solitary and eventually.”
Knowable to life track at the age of one hundred years old, body is being struggled against with paathogenic factor always, and disease is originally
Body is also at development change, has multiple different development and change stage.These are interim
Showing, disease is omnidistance, and card is the stage.Demonstrate,prove than simple symptom or name of disease more can comprehensively,
Deeply, the essence of disease change is disclosed definitely.Treating the same disease with different methods or different is there is again between disease and card
The relation that disease is ruled together, so health preserving to be paid attention to demonstrate,proving different disease, different card is with sick, or treating the same disease with different methods,
The relation for the treatment of different diseases with the same therapeutic principle.Deficiency of the kidney yin to be prevented and treated, insufficiency of kidney-YANG, kidney insufficiency, the hepatic and renal YIN deficiency,
The card such as deficiency of spleen-YANG and kidneyYANG, deficiency of heart-yin, deficiency of heart-YANG, depression of liver-QI, disarmony between the heart and kidney, the lung qi deficiency of YIN
Occur.These cards disclose the deficient of internal organs.So must prevent and treat for these tens kinds of diseases.
Huangdi's Internal Classics proposed the "prevention first" prevented trouble before it happens before more than 2,000 years,
Think that the tidemark of medical science is " sage's preventing diseases instead for the treatment of diseases is not controlled and disorderly controlled disorderly " (" element
Ask regulating life activities according to natural changes in four seasons big opinion ").To the Tang Dynasty, Sun Simiao propose " disease of upper doctor doctor's not disease, in
Doctor doctor is intended to the disease of disease, the disease of lower doctor doctor's disease " (" preemergency a thousand pieces of gold prescription volume 27 ", by disease
Disease is divided into " not sick ", " being intended to disease ", " sick " three levels, it is believed that upper doctor is maintaining healthy
Medicine of keeping good health, the traditional Chinese medical science is the preventive medicine of early intervention, and lower doctor is the treatment medical science for disease.
Under method for the treatment of instructs, experience accumulation in thousands of years, existing for the prescription preventing and treating a large amount of diseases
About thousand is first, but Chinese medicine is divided into the Chinese medicine of broad sense according to R&D of modern TCM, can be used for keeping healthy
The Chinese medicine of product, medicinal and edible Chinese medicine.The health preserving of medicinal and edible Chinese medicine upper doctor preventive treatment of disease is first
Choosing.And in existing about thousand first prescriptions, Fang Zhongquan is that the formula proportion of medicinal and edible Chinese medicine is little,
And prevent and treat common several of present majority with the formula and can relate to being full medicinal and edible Chinese medicine composition
Ten kinds of sick prescriptions are the most few.
Never sick is to gradually form to severe disease, and the most long-term process, it is right that present people recognizes
Main sick kind that human life and function harm highlight is: hypomnesis (dull-witted), tremulous pulse are hard
The diseases such as change, various thrombosis.
Accordingly, it would be desirable to develop one employing can prevent and treat harmful to human life and function disease, again
The Chinese medicine composition of the health care of the medicinal and edible Chinese medicine that the suitable people of energy take everyday.
Summary of the invention
In order to overcome the deficiencies in the prior art, the goal of the invention of the present invention is to provide one to have
Improve the integration of edible and medicinal herbs group of memory, arteriosclerosis, inhibition thrombosis, raising immunity
Compound.
Another goal of the invention of the present invention is to provide the preparation side of this medicinal and edible Chinese medicine compositions
Method.
An also goal of the invention of the present invention is to provide the health preserving of this medicinal and edible Chinese medicine compositions
Wine.
An also goal of the invention of the present invention is that the health preserving providing this medicinal and edible Chinese medicine compositions is drunk
Material, food etc..
Another goal of the invention of the present invention is to provide the application of this medicinal and edible Chinese medicine compositions.
In order to realize the object of the invention, the present invention provide one improve memory, arteriosclerosis,
Inhibition thrombosis, the Chinese medicine composition of raising immunity, it is characterised in that described Chinese drug-treated group
Compound comprises the Chinese medicine of following weight portion: Fructus Alpiniae Oxyphyllae 3-6 part, Poria 9-15 part, Rhizoma Polygonati 10-30
Part, Fructus Lycii 5-10 part.
In above-mentioned Chinese medicine composition:
Described weight portion can be unit of weight known to the field of medicaments such as μ g, mg, g, kg, also
Can be its multiple, such as 1/10,1/100,10 times, 100 times etc..
These, it is preferred to, Fructus Alpiniae Oxyphyllae 4-6 part, Poria 12-15 part, Rhizoma Polygonati 20-30 part, Chinese holly
Fructus Lycii 5-10 part.
Further, Chinese medicine composition of the present invention also includes 5-9 part Folium Mori, preferably 6-9 part Folium Mori.
Further, Chinese medicine composition of the present invention also includes 10-30 part Fructus Jujubae, preferably 10-20
Part Fructus Jujubae.
Chinese medicine composition of the present invention can also add Radix Angelicae Sinensis in right amount, and Radix Angelicae Sinensis consumption is 5-15 part, preferably
For 8-15 part.
Present invention also offers the preparation method of above-mentioned Chinese medicine composition, it comprises the following steps:
Weighing each Chinese medicine ingredients according to proportioning, be then soaked in water 30-60 minute by Chinese medicine, amount of water is
5-6 times of Chinese medicine gross weight, then boils, and after boiling, little fire boiling state, decocts 1-2 hour, cross leaching
Filtrate, adds the water of Chinese medicine gross weight 5-6 times, decocts 1 hour, filters, merges twice filtrate,
Concentrate, to obtain final product.
Containing the health preserving wine of above-mentioned Chinese medicine composition, it uses following steps to make: according to proportioning
Weighing each Chinese medicine ingredients, be then soaked in water 30-60 minute by Chinese medicine, amount of water is Chinese medicine gross weight
5-6 times of amount, then boils, and after boiling, little fire boiling state, decocts 1-2 hour, cross leaching filtrate, then
Add the water of Chinese medicine gross weight 5-6 times, decoct 1 hour, filter, merge twice filtrate, be concentrated into
Be equivalent to 1-2 times of crude drug weight, obtain Chinese medicine composition decoction, then Chinese medicine composition decoction
Blending with wine, the volume ratio of Chinese medicine composition decoction and this wine is 1:(1-5), health preserving wine.
Can also blend and obtain concentration in a series of difference, the Chinese medicament healthcare wine of different alcohol concentration.
Described wine is high quality liquor, rice wine, wine, yellow wine, red wine etc., wherein with high-quality
Chinese liquor is preferred, especially with aromatic Chinese spirit more preferably.Its number of degrees are less than or equal to 60 degree, as 53 degree,
42 degree, 38 degree etc..
The present invention containing above-mentioned Chinese medicine composition preparation can separately made by this Chinese medicine composition or by
This Chinese medicine composition and pharmaceutically acceptable carrier composition.
Described preparation is decoction, tablet, capsule, pill or oral liquid.Described pharmaceutically may be used
The carrier accepted refers to the pharmaceutical carrier that pharmaceutical field is conventional, selected from filler, binding agent, collapses
Solve agent, lubricant, solubilizing agent, suspending agent, wetting agent, pigment, essence, solvent, surface
One or more in activating agent or correctives.
Described filler selected from starch, pregelatinized Starch, dextrin, glucose, sucrose, lactose,
Lactose, microcrystalline Cellulose, mannitol, sorbitol or xylitol, preferably sorbitol, crystallite
Cellulose, lactose or pregelatinized Starch.
Described disintegrating agent is selected from cross-linking sodium carboxymethyl cellulose, polyvinylpolypyrrolidone, low-substituted hydroxypropyl
Base cellulose, carboxymethyl starch sodium or starch, preferably polyvinylpolypyrrolidone, low substituted hydroxy-propyl fibre
Dimension element or carboxymethyl starch sodium.
Described lubricant selected from magnesium stearate, Pulvis Talci, micropowder silica gel, PEG4000, PEG6000,
Sodium laurylsulfate, preferably magnesium stearate, Pulvis Talci.
Described binding agent selected from sodium carboxymethyl cellulose, hydroxypropyl methylcellulose, ethyl cellulose,
Polyvidone, starch slurry, sucrose, Icing Sugar, rubber cement, gelatin, Polyethylene Glycol, preferably hydroxypropyl first
Base cellulose, polyvidone.
Described solubilizing agent relies selected from sodium hydroxide, potassium hydroxide, sodium bicarbonate, meglumine, L-
Propylhomoserin, L-arginine, preferably sodium hydroxide, meglumine.
Described suspending agent is selected from micropowder silica gel, Cera Flava, cellulose, solid polyethylene glycol.
Described wetting agent is selected from glycerol, tween 80, ethoxy aluminium Oleum Ricini or lecithin.
Described solvent selected from ethanol, liquid polyethylene glycol, isopropanol, tween 80, glycerol, third
Glycol or vegetable oil, described vegetable oil is selected from soybean oil, Oleum Ricini, Oleum Arachidis hypogaeae semen, mixed oil etc..
Described surfactant is selected from dodecylbenzene sodium sulfonate, stearic acid, polyoxyethylene-polyoxy
Propylene copolymer, fatty acid Pyrusussuriensis be smooth or Polysorbate (tween) etc..
Described correctives is selected from aspartame, Sucralose, essence, steviosin, acesulfame potassium, lemon
Lemon acid or saccharin sodium.
It is also possible to the present invention is made various beverage or food containing above-mentioned Chinese medicine composition,
It is easy to carry, instant.
For during as beverage or food, Chinese medicine composition of the present invention can further include
10-30 part Semen Sesami Nigrum, 9-30 part Semen Coicis, preferably 15-30 part Semen Sesami Nigrum, 15-30 part Semen Coicis.
When preparing food, can first use and Semen Sesami Nigrum and Semen Coicis are crushed to 100-200 jointly
Mesh, then mix, finally according to food preparation processes with other raw material of Chinese medicine decocting in water extracting solution
Make, the dessert of such as all styles of, cookies etc..
Certainly, when for food processing, Poria can also divide two parts to add, a part of Fu
Siberian cocklebur can be pulverized and mixed together with Semen Sesami Nigrum, Semen Coicis and join in food.
Wherein, Semen Sesami Nigrum is preferred to fry with Semen Coicis.
Present invention also offers above-mentioned Chinese medicine composition at preparation treatment or preventing and treating body subhealthy status
Application in disease product.Application is specifically related to improve memory, arteriosclerosis, suppression blood
Bolt formed, improve immunity, improve prostate gland symptoms, resisting fatigue, improvement sleep, blood fat reducing,
Blood sugar lowering, and the aspect such as antioxidation, anticancer, beauty treatment, relieving constipation, fat-reducing.
Chinese medicine composition of the present invention can be also used for prevent and treat deficiency of the kidney yin, insufficiency of kidney-YANG, kidney insufficiency,
The hepatic and renal YIN deficiency, deficiency of spleen-YANG and kidneyYANG, deficiency of heart-yin, deficiency of heart-YANG, depression of liver-QI, disarmony between the heart and kidney etc. nine are demonstrate,proved
With lung heat clearing, moisturize.
The primary efficacy of the Chinese medicine composition of medicine-food two-purpose used by the present invention, meridian distribution of property and flavor, function
Cure mainly, compatibility potentiation, pharmacological action are discussed below respectively:
Fructus Alpiniae Oxyphyllae:
Meridian distribution of property and flavor: pungent, temperature.Return kidney, spleen channel.
Function cures mainly: warming the kidney to invigorate YANG, controlling nocturnal emission with astringent drugs reducing urination, warming spleen and stopping diarrha, takes the photograph saliva and stops saliva.Main use
In insufficiency of kidney-YANG, frequent urination and enuresis, emission and spermatorrhea, middle Jiao is cold, the cold pain of gastral cavity abdomen, vomiting and diarrhoea lack of appetite,
Mouth saliva gravity flow.
Pharmacological action: the activity of left atrium contracts power can be strengthened, there is cardiotonic.To reproduction
The impact of system, Fructus Alpinae Oxyphyllae extract can suppress the activity of prostaglandin synthetase.Have anticancer,
Defying age, improve the effect of memory.
Primary healthcare effect: have and improve the effect such as memory, antioxidation.
Poria:
Meridian distribution of property and flavor: sweet, light, flat.GUIXIN, spleen, kidney channel.
Function cures mainly: inducing diuresis to remove edema, eliminating dampness by diuresis, spleen invigorating, mind calming.Be mainly used in edema, phlegm retention,
Diarrhea due to hypofunction of the spleen, cardiopalmus, insomnia etc..
Pharmacological action: make the third paddy aminotransferase activity substantially reduce, prevent hepatic necrosis.Strengthen
Myocardial contraction, has obvious diuresis, improves immunity, blood sugar lowering, antitumor, promotes
Hemopoietic.
Primary healthcare effect: have enhancing immunity, blood sugar lowering, blood fat reducing, the liver protecting,
Improve memory, improve the effect such as anoxia endurance, antitumor.
Rhizoma Polygonati:
Meridian distribution of property and flavor: sweet, puts down, returns spleen, lung, kidney.
Function cures mainly: lung moistening YIN nourishing, invigorating the spleen and replenishing QI.Being mainly used in deficiency of the lung cough caused by dryness, consumptive disease is coughed hemoptysis,
Blood and essence asthenia, interior-heat quenches one's thirst, insufficiency of the spleen asthenia, and xerostomia lack of appetite is hard and dry.
Pharmacological action: to blood fat and the effect of arteriosclerosis: Rhizoma Polygonati decocting liquid and ethanol extraction
Serum cholesterol and glycerol three acid content can be significantly reduced, the speckle on aorta wall film can be made to subtract
Few and Coronary Artery Atherosclerosis alleviates.There is hypoglycemic activity, there is antioxidation, carry
The ability of high body free radical resisting, enhancing immunity etc. acts on.
Primary healthcare effect: there is blood fat reducing, blood sugar lowering, enhancing immunity, antioxidation, delay
Physical fatigue, the liver protecting etc. acts on.
Fructus Lycii:
Meridian distribution of property and flavor: sweet is flat.Return liver, kidney channel.
Function cures mainly: the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity, nourishing the lung to arrest cough.It is mainly used in lumbago due to renal deficiency,
Emission and spermatorrhea, sexual impotence, long fertility, interior-heat quenches one's thirst, blood deficiency and yellow complexion, poor vision, dizzy
Dizzy, deficiency of YIN phthisical cough, middle dizziness due to wind, fidgets due to deficiency insomnia, rheumatic arthralgia etc..
Pharmacological action: have blood sugar lowering, blood fat reducing and protect the liver, lipotropy;Have anti-
Function of tumor;There is resisting fatigue;Radioprotective;Anoxia enduring;Blood pressure lowering;Mutation;Antioxygen is turned into
With.
Primary healthcare effect: there is enhancing immunity, alleviating physical fatigue, antioxidation, alleviation
Asthenopia, the liver protecting etc. act on.
Radix Angelicae Sinensis:
Meridian distribution of property and flavor: sweet, pungent, temperature.Return liver, the heart, spleen channel.
Function cures mainly: replenishing and activating blood, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Cure mainly blood deficiency and yellow complexion, the moon
Through uncomfortable, amenorrhea dysmenorrhea, blood deficiency, stasis, all pains of cold in blood, traumatic injury, rheumatic arthralgia,
Ulcer sores, dryness of the intestine constipation etc..
Pharmacological action: the impact on cardiovascular system: Radix Angelicae Sinensis has blood fat reducing, hard to aorta
Change, aortic disease has certain protective role.Ligustilide from Angelica sinensis has suppression platelet aggregation
Effect.Radix Angelicae Sinensis and ferulic acid thereof have obvious anti thrombotic action.Radix Angelicae Sinensis polysaccharide has promotion and makes
The effect of blood function, increases the effect of coronary flow, has enhancing immunity function.Also have
Protect the liver, antitumor, radioprotective, antiinflammatory, antioxidation, the effect such as correction protein metabolism disorder.
Primary healthcare effect: have enhancing immunity, the liver protecting, promotes hemopoietic, expansion hat
Shape tremulous pulse and peripheral blood vessel.Suppression platelet aggregation, arrhythmia etc. acts on.
Fructus Jujubae:
Meridian distribution of property and flavor: sweet, temperature.Return spleen, stomach warp.
Function cures mainly: invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind, relaxes the property of medicine.It is mainly used in weakness of the spleen and stomach,
Anorexia and loose stool, blood deficiency and yellow complexion, palpitation and insomnia, women is dirty dry, irritability etc..
Pharmacological action: hypotensive effect: benzyl alcohol glycoside in Fructus Jujubae, naringenin (multipleization such as glucosides
Compound) there is notable hypotensive effect.Antimutagenic effect: Fructus Jujubae decocting liquid has antimutagenic effect.
In addition Fructus Jujubae still has certain antitumor, resisting I-type allergic reaction, resisting fatigue, the effect such as protects the liver.
Primary healthcare effect: there is enhancing immunity, alleviating physical fatigue, improvement sleep, protect
Hepatoprotective is dirty, improve the effects such as nutritional anemia.
Folium Mori:
Meridian distribution of property and flavor: sweet, bitter, cold.Return lung, Liver Channel.
Function cures mainly: dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, suppressing liver-YANG, liver heat removing and eyesight improving, and removing heat from blood is only
Blood.Be mainly used in anemopyretic cold, epidemic febrile disease from the beginning of, cough due to lung-heat, cough caused by dryness-heat, excessive rising of liver-YANG,
Conjunctival congestion is dim-sighted, and heat in blood coughs cards such as telling epistaxis.
Pharmacological action: hypoglycemic activity: Folium Mori total polysaccharides has significant hypoglycemic activity, and can
Improve the resistance to sugar ability of diabetic mice, increase liver glycogen content and reduce hepatic glucose, improve
Insulin level in normal rat blood.Additionally, its blood sugar lowering mechanism is also risen by some inorganic elementss
Certain effect.Impact on vascular system: rutin, Quercetin contained in Folium Mori can increase
The contractility of the in vitro and in place frog heart and cardiac output, and decreased heart rate.Rutin makes under Bufo siccus
Limb and rabbit ear vasoconstriction;The expansible coronary vasodilator of Quercetin.Rutin and Quercetin can keep
The normal resistance of blood capillary, reduces vascular permeability, can make because fragility increases hemorrhage
Blood capillary recovers normal elastic.Rutin and Cortex querci dentatae have certain hypotensive effect.
Primary healthcare effect: having blood sugar lowering, enhancing immunity, relieving constipation, functions of removing chloasma etc. is made
With.
Semen Sesami Nigrum:
Meridian distribution of property and flavor: sweet is flat.Return liver, kidney, large intestine channel.
Function cures mainly: tonification essence and blood, moisturizes laxation.It is mainly used in early whitening of beard and hair, dizziness and blurred vision,
Women's breast in puerperal is few, migratory arthralgia, and blood deficiency Tianjin is withered, dryness of the intestine constipation etc..Doctor trained in Western medicine examine into neurasthenia,
Hypertension, habitual constipation etc., belong to deficiency of the liver and kindey, blood and essence asthenia person.
Pharmacological action: anti-aging effects: Semen Sesami Nigrum can make aging phenomenon postpone occur, liver and
In testis, lipofuscin level reduces, and in blood plasma, content of vitamin E increases.The effect of cholesterol reducing:
Contained linoleic acid can reduce blood middle cholesterol content.
Primary healthcare effect: there is the effects such as blood sugar lowering, blood fat reducing, loosening bowel to relieve constipation.
Semen Coicis:
Meridian distribution of property and flavor: sweet, light, cool.Return spleen, stomach, lung meridian.
Function cures mainly: inducing diuresis to remove edema, eliminating dampness by diuresis, spleen invigorating, eliminating impediment, clearing away heat and discharging pus.It is mainly used in
Edema, dysuria, tinea pedis, diarrhea due to hypofunction of the spleen, arthralgia chiefly caused by damp pathogen contracture, pulmonary fistula, lung abscess, acute appendicitis,
Stranguria with turbid discharge, leucorrhea etc..
Pharmacological action: the effect to central nervous system: Semen Coicis has calmness, analgesic activity.
Antitumaous effect: Semen Coicis ethanol extract lumbar injection has suppression, energy to mice ehrlich carcinoma
It is obviously prolonged the existence effect of animal.
In addition Semen Coicis also induce ovulation, lower the temperature with fall heat, suppression trypsin, antibacterial,
Suppression multisynaptic reflex, blood sugar lowering, fall blood calcium, the effect of enhancing immunologic function.
Primary healthcare effect: there is the effects such as enhancing immunity, blood sugar lowering, functions of removing chloasma.
The present invention improves immunity, arteriosclerosis, inhibition thrombosis, improves memory
Integration of edible and medicinal herbs compositions, has the advantages that
Based on Chinese medicine composition the most of the present invention chooses medicinal and edible Chinese medicine raw material, grind through overtesting
Study carefully, it is determined that with the Fructus Alpiniae Oxyphyllae of specific consumption, Poria, Rhizoma Polygonati, Fructus Lycii for compatibility basis,
Reach the function of collaborative compatibility potentiation, obtain and improve immunity, arteriosclerosis, suppression thrombosis
Form, improve effect of memory;Assist a ruler in governing a country addition Folium Mori, Fructus Jujubae, Radix Angelicae Sinensis simultaneously and further,
And Semen Sesami Nigrum and Semen Coicis, can promote or widen effect of compositions further.
Chinese medicine composition the most of the present invention can be used for prevent and treat deficiency of the kidney yin, insufficiency of kidney-YANG, kidney insufficiency,
The hepatic and renal YIN deficiency, deficiency of spleen-YANG and kidneyYANG, deficiency of heart-yin, deficiency of heart-YANG, depression of liver-QI, disarmony between the heart and kidney etc. nine are demonstrate,proved
With lung heat clearing, moisturize.
Medicinal and edible Chinese medicine compositions the most of the present invention all returns kidney channel, has the kidney invigorating effect.
4. the Chinese medicine composition of the present invention has supplementing the brain benefit marrow effect, can improve brain function.
5. ACTH adrenocorticotropin (swashing) element reaction is reduced by old atrophy of adrenal gland, urine
Middle ketone corticosteroid discharge capacity is lower than between twenty and fifty, and hypoendocrinism is one of old and feeble reason.
Kidney storing essence, the raw marrow of essence, brain being the marrow sea.Therefore kidney essense fills Sheng, then brains are sufficient and limbs action spirit
Living, knowledge is clever and quick, and so-called " excess of marrow-reservoir, then light strength is strong " essence is full of marrow and fills, then brain is from strong,
The strong wisdom of then giving birth to of brain, strong will, profit knowledge, make light of one's life by commiting suicide and prolong life.Therefore prevent and treat alzheimer disease many from
Kidney tonifying marrow facilitating is started with, and otherwise loses intelligence, then dull-witted.
Chinese medicine composition the most of the present invention has and improves memory, arteriosclerosis, suppression thrombosis shape
Become, improve immunity, improve prostate gland symptoms, resisting fatigue, improvement sleep, blood fat reducing, fall
Blood glucose, and the aspect effect such as antioxidation, anticancer, beauty treatment, relieving constipation, fat-reducing.
Detailed description of the invention
Following example are used for illustrating the present invention, but are not limited to the scope of the present invention.
Embodiment 1: Chinese medicine composition decoction
1, composition: Fructus Alpiniae Oxyphyllae 40g, Poria 150g, Rhizoma Polygonati 250g, Fructus Lycii 100g, when
Return 100g, Fructus Jujubae 200g (adding up to 840g).
2, preparation method: weigh each Chinese medicine ingredients according to proportioning, is then soaked in water 40 by Chinese medicine
Minute, amount of water is 6 times (i.e. 5040g) of Chinese medicine gross weight, then boils, little fire boiling after boiling
State, decocts 2 hours, crosses leaching filtrate, adds the water (i.e. 5040g) of Chinese medicine gross weight 6 times,
After boiling, little fire boiling state, decocts 1 hour, filters, merge twice filtrate, be evaporated to 840ml,
Obtain Chinese medicine composition decoction (every ml 1g Han crude drug).
Embodiment 2: Chinese medicine composition decoction
1, composition: Fructus Alpiniae Oxyphyllae 50g, Poria 100g, Rhizoma Polygonati 200g, Fructus Lycii 80g, Radix Angelicae Sinensis
120g, Fructus Jujubae 250g (add up to 800g).
2, preparation method: weigh each Chinese medicine ingredients according to proportioning, is then soaked in water 40 by Chinese medicine
Minute, amount of water is 5 times (i.e. 4000g) of Chinese medicine gross weight, then boils, little fire boiling after boiling
State, decocts 2 hours, crosses leaching filtrate, adds the water (i.e. 4000g) of Chinese medicine gross weight 5 times,
After boiling, little fire boiling state, decocts 1 hour, filters, merge twice filtrate, be evaporated to 1600ml,
Obtain Chinese medicine composition decoction (every ml 0.5g Han crude drug).
Embodiment 3: Chinese medicine composition decoction
1, composition: Fructus Alpiniae Oxyphyllae 60g, Poria 120g, Rhizoma Polygonati 150g, Fructus Lycii 60g (add up to
390g)。
2, preparation method: weigh each Chinese medicine ingredients according to proportioning, is then soaked in water 40 by Chinese medicine
Minute, amount of water is 5 times (i.e. 1950g) of Chinese medicine gross weight, then boils, little fire boiling after boiling
State, decocts 2 hours, crosses leaching filtrate, adds the water (i.e. 1950g) of Chinese medicine gross weight 5 times,
After boiling, little fire boiling state, decocts 1 hour, filters, merge twice filtrate, be evaporated to 700ml,
Obtain Chinese medicine composition decoction (every ml 0.55g Han crude drug).
Embodiment 4: Chinese medicine composition decoction
1, composition: Fructus Alpiniae Oxyphyllae 30g, Poria 100g, Rhizoma Polygonati 250g, Fructus Lycii 100g, Mulberry
Leaf 100g (adds up to 580g).
2, preparation method: weigh each Chinese medicine ingredients according to proportioning, is then soaked in water 40 by Chinese medicine
Minute, amount of water is 5 times (i.e. 2900g) of Chinese medicine gross weight, then boils, little fire boiling after boiling
State, decocts 2 hours, crosses leaching filtrate, adds the water (i.e. 2900g) of Chinese medicine gross weight 5 times,
After boiling, little fire boiling state, decocts 1 hour, filters, merge twice filtrate, be evaporated to 600ml,
Obtain Chinese medicine composition decoction (every ml 0.96g Han crude drug).
Embodiment 5: prepared by health preserving medicated wine
1, composition: Fructus Alpiniae Oxyphyllae 60g, Poria 90g, Rhizoma Polygonati 150g, Fructus Lycii 60g, Radix Angelicae Sinensis
80g, Fructus Jujubae 150g, Folium Mori 60g (add up to 650g).
2, preparation method:
Weigh each Chinese medicine ingredients according to proportioning, then Chinese medicine is soaked in water 40 minutes, amount of water
For 5 times of Chinese medicine gross weight, then boiling, after boiling, little fire boiling state, decocts 2 hours, crosses leaching
Filtrate, adds the water of Chinese medicine gross weight 6 times, and after boiling, little fire boiling state, decocts 1 hour, filter,
Merging twice filtrate, be evaporated to 1300ml, (every ml is containing raw to obtain Chinese medicine composition decoction
Medicine 0.50g).
By Chinese medicine composition decoction and 53 degree of Chinese liquor, Chinese medicine composition volume and this Chinese liquor volume it
Ratio can be 1:1, health preserving wine, every ml crude drug Han 0.25g.
Embodiment 6: prepared by health preserving medicated wine
1, composition: Fructus Alpiniae Oxyphyllae 30g, Poria 150g, Rhizoma Polygonati 220g, Fructus Lycii 100g, when
Return 100g, Fructus Jujubae 220g (adding up to 820g).
2, preparation method:
Chinese medicine composition decoction is prepared according to the method for embodiment 2.
Chinese medicine composition decoction and 39 degree of aromatic Chinese spirits are blent, Chinese medicine composition volume with should
The ratio of Chinese liquor volume can be 1:1, health preserving wine, every ml crude drug Han 0.25g.
Embodiment 7: prepared by health preserving medicated wine
1, composition: Fructus Alpiniae Oxyphyllae 40g, Poria 120g, Rhizoma Polygonati 250g, Fructus Lycii 80g, Folium Mori
90g, Fructus Jujubae 200g (add up to 780g).
2, preparation method:
Chinese medicine composition decoction is prepared according to the method for embodiment 2.
Chinese medicine composition decoction and 39 degree of aromatic Chinese spirits are blent, Chinese medicine composition volume with should
The ratio of Chinese liquor volume can be 1:1, health preserving wine, every ml crude drug Han 0.25g.
Embodiment 8: tablet (following dosage is 10 doses of consumptions)
1, composition: Fructus Alpiniae Oxyphyllae 50g, Poria 150g, Rhizoma Polygonati 250g, Fructus Lycii 100g, when
Return 100g, Fructus Jujubae 200g, Folium Mori 80g (adding up to 920g).
2, preparation method: above-mentioned Chinese medicine is soaked 30 minutes, the water surface is higher than raw material Chinese medicine,
Amount of water is 6 times of total dose, and after boiling, little fire boiling state, maintains liquid level to be higher than raw material Chinese medicine height,
Decoct two hours, cross leaching filtrate, add the water of total dose 5 times, little fire boiling state, dimension after boiling
Hold liquid level and be higher than raw material Chinese medicine height, decoct two hours, filter and merge twice filtrate, through subtracting
Pressure concentrates (pressure 0.06MPa, temperature 65 DEG C) extremely dry cream, pulverizes, obtains 230g Chinese medicine composition
Thing (yield is 25%, every g 4g Han crude drug).
3, tablet: 100g Chinese medicine composition mixes with 50g starch, crosses 60 mesh sieves, pelletizes, dry
Dry, then add 4g magnesium stearate, tabletting, obtain tablet.
Embodiment 9: capsule
1, composition: Fructus Alpiniae Oxyphyllae 40g, Poria 100g, Rhizoma Polygonati 300g, Fructus Lycii 50g, Radix Angelicae Sinensis
80g, Fructus Jujubae 150g, Folium Mori 50g (add up to 770g).
2, preparation method: above-mentioned Chinese medicine is soaked 50 minutes, the water surface is higher than raw material Chinese medicine,
Amount of water is 5 times of total dose, and after boiling, little fire boiling state, maintains liquid level to be higher than raw material Chinese medicine height,
Decoct two hours, cross leaching filtrate, add the water of total dose 5 times, little fire boiling state, dimension after boiling
Hold liquid level and be higher than raw material Chinese medicine height, decoct two hours, filter and merge twice filtrate, through subtracting
Pressure concentrates (pressure 0.06MPa, temperature 65 DEG C) extremely dry cream, pulverizes, obtains 200.2g Chinese drug-treated group
Compound (yield is 26%, every g 3.85g Han crude drug).
3, capsule: Chinese medicine composition crosses 300 mesh sieves, weighs Chinese medicine composition 100g, adds total
The magnesium stearate of weight 2%, is distributed into capsule,.
Embodiment 10: pill
1, composition: Fructus Alpiniae Oxyphyllae 60g, Poria 150g, Rhizoma Polygonati 250g, Fructus Lycii 80g, Radix Angelicae Sinensis
100g, Fructus Jujubae 100g, Semen Sesami Nigrum 200g, Semen Coicis 100g (add up to 1040g).
2, preparation method: above-mentioned Chinese medicine is soaked 60 minutes, the water surface is higher than raw material Chinese medicine,
Amount of water is 8 times of total dose, and after boiling, little fire boiling state, maintains liquid level to be higher than raw material Chinese medicine height,
Decoct two hours, cross leaching filtrate, add the water of total dose 6 times, little fire boiling state, dimension after boiling
Hold liquid level and be higher than raw material Chinese medicine height, decoct two hours, filter and merge twice filtrate, through subtracting
Pressure concentrates (pressure 0.06MPa, temperature 65 DEG C) to dry cream.
3, pill: water is general for ball, coating,.
Embodiment 11: oral liquid
1, composition: Fructus Alpiniae Oxyphyllae 40g, Poria 125g, Rhizoma Polygonati 240g, Fructus Lycii 100g, when
Return 80g, Fructus Jujubae 250g, Folium Mori 90g (adding up to 925g).
2, preparation method: above-mentioned Chinese medicine is soaked 45 minutes, the water surface is higher than raw material Chinese medicine,
Amount of water is 8 times of total dose, and after boiling, little fire boiling state, maintains liquid level to be higher than raw material Chinese medicine height,
Decoct two hours, cross leaching filtrate, add the water of total dose 6 times, little fire boiling state, dimension after boiling
Hold liquid level and be higher than raw material Chinese medicine height, decoct two hours, filter merging filtrate, be concentrated into relatively
Density is the clear paste of 1.17 (70 DEG C), and (yield is 28%, every g to obtain 259g Chinese medicine composition
Containing crude drug 3.57g).
3, oral liquid: Chinese medicine composition 100g adds ethanol, makes alcohol content reach 65%, uses hydroxide
Sodium regulation pH to 6.8, stands 36 hours, filters, and adds ethanol, make alcohol content reach in filtrate
75%, stand 24 hours, filter, by filtrate recycling ethanol to without alcohol taste, heat micro-boiling 15 minutes,
Stirring evenly, add water to 1000ml, stir evenly, filter, embedding, (every ml contains 0.333g to obtain oral liquid
Crude drug).
Embodiment 12: cookies
1, composition: Fructus Alpiniae Oxyphyllae 50g, Poria 120g, Rhizoma Polygonati 150g, Fructus Lycii 60g, Radix Angelicae Sinensis
120g, Fructus Jujubae 180g, Folium Mori 80g, Semen Sesami Nigrum 300g, Semen Coicis 200g (add up to 1260g).
2, preparation method: the Chinese medicine in addition to Semen Sesami Nigrum and Semen Coicis is soaked 45 minutes,
The water surface is higher than raw material Chinese medicine, and amount of water is 8 times of total dose, and after boiling, little fire boiling state, maintains liquid level
Higher than raw material Chinese medicine height, decoct two hours, cross leaching filtrate, add the water of total dose 6 times,
After boiling, little fire boiling state, maintains liquid level higher than raw material Chinese medicine height, decocts two hours, filter and merge
Filtrate;
Then Semen Sesami Nigrum 300g and Semen Coicis 200g is crushed to jointly 100 mesh, adds and merge filter
Liquid, adds 1000g Self-raising flour, butter 600g, Saccharum Sinensis Roxb. 500g, egg 250g, presses
Bakee according to cookies preparation technology and form.
Embodiment 13: cookies
1, composition: Fructus Alpiniae Oxyphyllae 40g, Poria 100g, Rhizoma Polygonati 120g, Fructus Lycii 80g, Radix Angelicae Sinensis
100g, Fructus Jujubae 150g, Folium Mori 70g, Semen Sesami Nigrum 250g, Semen Coicis 250g (add up to 1160g).
2, preparation method: the Chinese medicine in addition to Semen Sesami Nigrum, Semen Coicis and Poria 30g is added water logging
Steeping 45 minutes, the water surface is higher than raw material Chinese medicine, and amount of water is 8 times of total dose, little fire boiling state after boiling,
Maintain liquid level higher than raw material Chinese medicine height, decoct two hours, cross leaching filtrate, add total medicine
Measuring the water of 6 times, after boiling, little fire boiling state, maintains liquid level higher than raw material Chinese medicine height, decocts two hours,
Filter merging filtrate;
Then Poria 30g, Semen Sesami Nigrum 250g and Semen Coicis 250g are crushed to 100 mesh jointly, add
Enter merging filtrate, add 1500g Self-raising flour, butter 800g, Saccharum Sinensis Roxb. 600g, egg 200
G, bakees according to cookies preparation technology and forms.
Following experimental example, is that product of the present invention is carried out when clinic is tested.
Experimental example 1
By testing the following examination personnel of taking, result of the test is as follows:
1) Soviet Union XX, man, 79 years old, suffer from dissection of aorta Type B arteriosclerosis heavier, development is very fast,
CTA confirms, in blood vessel, calcification point is intensive.Take embodiment 1 decoction 1 year, then do CTA confirmation
Within this year, vascular condition is without deteriorating again, and conscious health is than the most relatively comfortable, and Type B interlayer is more stable.
2) Zhao XX, man, 65 years old, right hand end water bowl trembled width at about 1 centimeter, takes embodiment 1
After decoction one month, do not tremble, sometimes tremble its amplitude also only 0.5 centimeter.
3) week XX, man, 55 years old, double palmaris brevis positions colour of skin was mulberry, and blood circulation difference is not
Freely.Taking embodiment 2 decoction one month, the both hands palmaris brevis position colour of skin is normal skin tone, without mulberry.
4) Lee XX, man, 70 years old, the right hand write hand shaking, writes out its body of word and sees and tremble sample.Clothes are real
Execute example 1 decoction one month, the word not trembling font can be write out with normal speed.
5) discipline XX, man, 56 years old, the right hand stretched, and the back of the hand is upwards raise one's hand, automatic appearance
Tremble 2 millimeters, take embodiment 3 decoction one month, then stretch out one's hand with same attitude, lose and tremble.
6) Lee XX, female, 60 years old, blood stasis blood deficiency complexion committee was yellow, and void is not mended, malaise,
Take embodiment 1 decoction after three weeks conscious energy foot, complexion is obviously improved.
7) what XX, man, 65 years old, tired think of, conscious insobriety was clear, and hypomnesis is the brightest
Aobvious, within five days, front thing is all forgotten, and takes embodiment 4 decoction after two weeks, and conscious thinking is relatively flexible,
Ponder a problem the most hard, five days front things relatively clear can be recalled, do not remember.
8) Lu XX, female, 55 years old, to sleep very poor, one night only falls asleep 4 hours, and memory is very poor,
Taking embodiment 1 decoction one week, can fall asleep the most every night more than 6 hours, memory has clear improvement.
9) XX is opened, man, 56, male climacteric syndrome, vigorous without morning, take embodiment 1 decoction
20 days, occur that morning vigorous, takes 30 days, has every day vigorous in morning.
10) high XX, man, 78 years old, over 20 years, about Sublingual, two big blood vessels were atropurpureus,
Lower lip is mulberry, takes embodiment 1 decoction 30 days, and about Sublingual, two big blood vessels (are just becoming Lycoperdon polymorphum Vitt
Often color), lower lip becomes pink.
11) Lee XX, man, 75 years old, phlegm-damp type body constitution was more daily when going upstairs, and lower limb is felt and seemingly filled lead,
Breathing greatly then occur in upper three floors, take embodiment 1 decoction surrounding, conscious go upstairs unconsciously painstaking,
Also occur without and breathe greatly.
12) high XX, man, 73 years old, conscious QI and blood was not smooth, and heavy sensation of the body is weak, and walking often, step can only
Stepping 30 centimeters, take embodiment 1 decoction surrounding, conscious body strength is strong, and often step of walking can step 60
Centimetre.
13) king XX, female, 40 years old, flu often occurs, immunity is relatively low, and often sense is in fatigue
State.Taking embodiment 1 decoction surrounding, do not occur flu over the past half year, conscious the most tired, energy is relatively
The most also foot.
14) king XX, man, 68 years old, prostatic hyperplasia pSA mark was much larger than 10, and urine 3-4 is played in every place
Secondary, to sleep poor, panesthesia's prostate position, in irriate state, takes embodiment 1 decoction after three weeks, continues
Continuous clothes, the most only get up and urinate once, and prostate irriate is the most inconspicuous.
Experimental example 2
With certain the most dry office dining room in the product news conference of Yi Gong hotel, Beijing, through 30 participants
Scholar and 60 veteran cadres take embodiment 5 health preserving wine, all feel not top, non-dry throat, blurt out
Along larynx, be in a cheerful frame of mind, make light of one's life by commiting suicide strong, energy is sufficient, without any side effects.
The merits such as integration of edible and medicinal herbs Chinese medicine composition of the present invention has arteriosclerosis, inhibition thrombosis
Effect.Its medicated wine then can potentiation further.Human body takes in ethanol in right amount can increase blood high-density
Lipoprotein, reduces low density lipoprotein, LDL.Low density lipoprotein, LDL is gallbladder in atheromatous plaque
The main provider of sterin.High density lipoprotein is smooth with low density lipoprotein, LDL competition blood vessel wall
Receptor on myocyte's serous coat, thus suppress vascular smooth muscle cell community and accumulation low-density
Lipoprotein, and then the formation of prevention of arterial atherosclerotic plaque.Wine is as the carrier of medicine, meeting
Improve the bioavailability of this Chinese medicine composition further.
Experimental example 3
Medicinal and edible Chinese medicine compositions of the present invention (combines with embodiment 1 Six-element medicinal and edible Chinese medicine
Thing) through modern Chinese medicine quantizing resonance instrument, (QRS quantum resonance spectrometer Hebei is received hundred river science and technology and is opened
Send out company limited) measure, as follows to 29 tonification data of human body, without any side effects, health preserving
Disease prevention index is ideal.
Human body generally normal value decision method:
Subhealth state (0 to+8), healthy normal value (+9 to+21), morbid state (0 to-21).
Result shows, QRS quantum detection goes out the health-preserving and disease-preventing rehabilitation of Chinese medicine composition of the present invention and refers to
Mark the most outstanding.Be improved particularly that immunologic function, the kidney invigorating, alleviation be extremely tired, inhibition thrombosis,
The function improving the aspect such as blood circulation, arteriosclerosis is the most notable.And have estimable
The good function improving memory;Human experimentation, effect curve and quantum detection characteristic coincide or
Close.
Take medicinal and edible Chinese medicine compositions of the present invention (being used for supplementing above quantal data) can help
Help patient to change to subhealth state, the quantal data of sub-healty adults can be made to become the quantum of Healthy People
Data, can make the quantal data of Healthy People become the quantal data of more Healthy People.Therefore reach foster
Life, prevention and the effect of rehabilitation.
In sum and clinical experiment confirm, the Chinese medicine composition of the present invention can be used for preventing and treating kidney yin
Void, insufficiency of kidney-YANG, kidney insufficiency, the hepatic and renal YIN deficiency, deficiency of spleen-YANG and kidneyYANG, deficiency of heart-yin, deficiency of heart-YANG,
Depression of liver-QI, disarmony between the heart and kidney etc. nine is demonstrate,proved.Have and improve memory, arteriosclerosis, suppression blood
Bolt formed, improve immunity, improve prostate gland symptoms, resisting fatigue, improvement sleep, blood fat reducing,
Blood sugar lowering, and the aspect effect such as antioxidation, anticancer, beauty treatment, relieving constipation, fat-reducing.
Although, used general explanation, detailed description of the invention and test, to this
Bright make detailed description, but on the basis of the present invention, it can have been made some modifications or improvements,
This will be apparent to those skilled in the art.Therefore, without departing from present invention spirit
On the basis of these modifications or improvements, belong to the scope of protection of present invention.
Claims (10)
1. one kind is improved immunity, arteriosclerosis, inhibition thrombosis, improves memory
Chinese medicine composition, it is characterised in that the Chinese medicine that described Chinese medicine composition comprises following weight portion is former
Material: Fructus Alpiniae Oxyphyllae 3-6 part, Poria 9-15 part, Rhizoma Polygonati 10-30 part, Fructus Lycii 5-10 part.
Chinese medicine composition the most according to claim 1, it is characterised in that described Chinese drug-treated group
Compound comprises the raw material of Chinese medicine of following weight portion: Fructus Alpiniae Oxyphyllae 4-6 part, Poria 12-15 part, Rhizoma Polygonati
20-30 part, Fructus Lycii 5-10 part.
Chinese medicine composition the most according to claim 1 and 2, it is characterised in that also include 5-9
Part Folium Mori.
4. according to the Chinese medicine composition described in claim 1-3 any one, it is characterised in that also
Including 10-30 part Fructus Jujubae.
5. according to the Chinese medicine composition described in claim 1-4 any one, it is characterised in that also
Including 5-15 part Radix Angelicae Sinensis.
6. according to the Chinese medicine composition described in claim 1-5 any one, it is characterised in that also
Including 10-30 part Semen Sesami Nigrum, 9-30 part Semen Coicis.
7. containing the health preserving wine of Chinese medicine composition described in claim 1-5 any one, its feature exists
In, use following steps to make: to weigh each Chinese medicine ingredients, medicinal water in then inciting somebody to action according to proportioning
Soaking 30-60 minute, amount of water is 5-6 times of Chinese medicine gross weight, then boils, little fire boiling after boiling
State, decocts 1-2 hour, crosses leaching filtrate, adds the water of Chinese medicine gross weight 5-6 times, decocts 1
Hour, filter, merge twice filtrate, be concentrated into be equivalent to crude drug weight 1-2 times, in obtaining
Drug composition decoction, then Chinese medicine composition decoction is blent with wine, Chinese medicine composition decoction with should
The volume ratio of wine is 1:(1-5), health preserving wine.
8. containing the preparation of Chinese medicine composition described in any one of claim 1-6, by this Chinese medicine composition
Separately made or be made up of this Chinese medicine composition and pharmaceutically acceptable carrier.
9. health preserving wine described in Chinese medicine composition, claim 7 described in any one of claim 1-6,
Preparation described in claim 8 is in preparation treatment or preventing and treating body subhealthy status disease product
Application.
Application the most according to claim 9, it is characterised in that described application is for improving note
Recall power, arteriosclerosis, inhibition thrombosis, raising immunity, improve prostate gland symptoms,
Resisting fatigue, improve sleep, blood fat reducing, blood sugar lowering, antioxidation, anticancer, improve looks, relieving constipation.
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CN106995772A (en) * | 2017-05-18 | 2017-08-01 | 江苏洋河酒厂股份有限公司 | A kind of health liquor of strengthen immunity |
CN109757582A (en) * | 2018-12-29 | 2019-05-17 | 江苏鹤莱科技有限公司 | Improve the nutritional food formula of benign prostate hyperplasia shape |
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CN106974285A (en) * | 2017-03-31 | 2017-07-25 | 江苏康缘药业股份有限公司 | A kind of Chinese medicine composition and its application |
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