CN103316144B - Chinese medicine composition capable of invigorating qi and blood, nourishing yin and yang, improving immunity, resisting to fatigue and inhibiting thrombogenesis - Google Patents
Chinese medicine composition capable of invigorating qi and blood, nourishing yin and yang, improving immunity, resisting to fatigue and inhibiting thrombogenesis Download PDFInfo
- Publication number
- CN103316144B CN103316144B CN201310284475.3A CN201310284475A CN103316144B CN 103316144 B CN103316144 B CN 103316144B CN 201310284475 A CN201310284475 A CN 201310284475A CN 103316144 B CN103316144 B CN 103316144B
- Authority
- CN
- China
- Prior art keywords
- chinese medicine
- medicine composition
- radix
- blood
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Abstract
The invention relates to a Chinese medicine composition capable of invigorating qi and blood, nourishing yin and yang, improving immunity, resisting to fatigue and inhibiting thrombogenesis. The Chinese medicine composition capable of invigorating qi and blood, nourishing yin and yang, improving immunity, resisting to fatigue and inhibiting thrombogenesis contains the following traditional Chinese medicines: prepared rehmannia root, Chinese angelica, codonopsis pilosula, medlar and morinda officinalis. The Chinese medicine composition provided by the invention can be used for treating climacteric syndrome, enhancing immunity and treating thrombus.
Description
Technical field
The present invention relates to Chinese medicine composition, be specifically related to a kind of benefiting vital QI and blood, yin nourishing Yiyang, improve immunity, resisting fatigue, the thrombotic Chinese medicine composition of inhibition and preparation method thereof.
Background technology
Hypoimmunity:
Immunity is the defense mechanism of human body self, is human body identification and any foreign body (virus, antibacterial etc.) of eliminating external intrusion; Process the ability of self cell and identification and processing vivo mutations cell and the virus infected cell of old and feeble, damage, dead, degeneration.Modern immunology thinks, immunity is human body identification and the physiological reaction of getting rid of " dissident ".What in human body, carry out this function is immune system.
Immunity is that body is identified and gets rid of antigenicity foreign body, safeguards the physiological equilibrium of self and stable a kind of function, i.e. defence, certainly steady and supervision three large functions.The immunologic function of body is to produce in long-term biological evolution process.Immunne response is carried out in body immune system, and immune system is made up of immune organ, immunocyte and immune molecule again, is carried out respectively by innate immunity (nonspecific immunity) and acquired immunity (specific immunity).Wherein acquired immunity is completed by cellular immunity and body fluid immunity close fit.
Hypoimmunity is to cause immune system can not normally bring into play protective effect by a variety of causes, and doctor trained in Western medicine is referred to as " sub-health state ".Because the immunity of human body depends on gene, environmental factors mostly, the low reason of neonatal immunity power is that immune system is grown not mature enough, it is perfect that function is still owed, and environmental factors generally refers to the aspects such as diet, sleep, motion, pressure more, wherein diet has conclusive power of influence, because the composition of some food can be assisted stimulating immune system, strengthen immunocompetence.If lack these important nutrient compositions, can have a strong impact on the immune system function of health.
Therefore, improve immunity and resisting fatigue and also become the focus of growing interest, exploitation just has vast social meaning taking enhancing immunity and alleviating physical fatigue as the health food of function.
Patient or immunologic hypofunction suffers virus infraction, or dysimmunity produces irritated allergy, or immunologic derangement produces autoimmune.Modern medicine is in the mechanism and diagnosis of above-mentioned disease, and there is a profound understanding and various detection meanss, but in the treatment of disease, still stay in " primary stage ", and the adjustment to immunologic function and recovery lack effective means and medicine.Many patients have no alternative but to rely on hormone to subsist, because prolonged application hormone side effect layer goes out constantly, has endless trouble.
Regulate separately the food of immunity to have Stichopus japonicus, purple palpus ginseng, Ganoderma, fresh Radix Raphani, Radix Ginseng, fresh royal jelly, mushroom, vitamin, chicken soup, Bulbus Allii, sheep placental extract, newborn immune protein, lactalbumin etc.
Regulate the Chinese patent medicine of immunity to have: BUZHONG YIQI WAN, YUPINGFENG SAN, GUIPI WAN, JINGUI SHENQI WAN etc.
Tired:
Fatigue is a kind of subjective uncomfortable sensation.
Fatigue claims again tired, is the discomfort of subjective a kind of fatigue and weak, but objectively can be under equal conditions, loses it and completes normal activity or the ability to work be originally engaged in.
Feel fatigue and be not special symptom, a lot of diseases all can cause fatigue, and various disease causes fatigue in various degree, and some disease performance more obviously can be used as medical onset symptoms sometimes.
Modern Chinese medicine thinks, fatigue is a name of disease, has its etiology and pathogenesis, is commonly encountered diseases, frequently-occurring disease clinically, is new sick kind that must pay attention to, is attributed to subhealth state category, relates to the vital organs of the human body, mainly taking spleen, liver, kidney as main.Can recuperate under medical treatment by Chinese medical discrimination prescription, to reach the object of prevention, treatment, control.
The tired traditional Chinese medical science " deficient " category that belongs to, due to the deficiency syndrome and mental change (or not smooth) double factor of first QI consumed wound.In treatment, not only want tonify deficiency righting, tired the calming the nerves of also should dispelling.On the one hand, tonify deficiency primordial QI reinforcing, nourishes body, empty must benefit, and canonical is prosperous, tired from removing; On the other hand, adjust smooth will, comfortable smooth meaning, refreshing must peace, the heart is peaceful, and fatigue can disappear.
The single medicinal material of resisting fatigue has: Radix Ginseng, Radix Notoginseng, Ganoderma, Fructus Schisandrae Chinensis, Radix Et Caulis Acanthopanacis Senticosi, Tremella, Radix Ophiopogonis, Colla Corii Asini etc.
The Chinese patent medicine of conventional resisting fatigue has: YIGUANJIAN, power reach oral liquid, oral liquid of ginseng tonic, spermatogenesis drink etc.
Cerebral thrombosis:
Cerebral thrombosis is that the arterial blood tube wall of the supply brain that causes of many reasons is coarse, sclerosis, blood flow are slack-off, blood constituent and viscosity change, cause Mottling formation, tube chamber to narrow, speckle comes off, vascular occlusion and local brain tissue ischemia and necrosis, it is different with degree that obturation, the embolus of different tremulous pulsies affects position, the corresponding neurological symptom of clinical appearance and sign.Commonly encountered diseases is because atherosclerosis, normal accompanied with hypertension and diabetes, and minority is cerebral arteritis, cerebrovascular malformation, polycythemia vera etc.
Its diagnostic point is: 1) age many more than 50 years old with atherosclerosis, diabetes, hyperlipemia; 2) previously there is transient ischemic attack history; 3) onset is slow, how under rest state, to fall ill, and symptom reached peak at several hours to 1-2d, has internal carotid artery or the performance of Vertebro-basilar System disordered brain function; 4) consciousness is many does not lose, many no headaches, vomiting; 5) auxiliary examination: it is not high that waist is worn cerebrospinal pressure, cell number and biochemical normal, head CT is after 24h, can find low-density kitchen range, other, hemorheology, electroencephalogram, bring out current potential, transcranial Doppler sonography, Magnetic Resonance Imaging, cerebral angiography etc. all contribute to diagnosis and state of an illness share price.
Its western medical treatment, to control blood pressure, increases cerebral blood flow, improves cerebral blood circulation, controls cerebral edema, thromboembolism preventing treatment, cerebral metabolism activator, cerebral protective agent etc.
The traditional Chinese medical science is mainly divided into three types such as the turbid illiteracy of expectorant is closed, blood stasis due to qi deficiency, the hepatic and renal YIN deficiency, and method for the treatment of is closed so that clearing away phlegm is logical respectively, benefiting QI for activating blood circulation, disperse blood stasis and dredge collateral, and nourishing YIN to subdue liver-wind etc., wherein blood stasis due to qi deficiency side's medicine is that BUYANG HUANWU TANG adds Scorpio, Scolopendra.
Climacteric syndrome:
Be exactly climacteric the transition period of being stepped into when old age by the middle age, climacteric men and women there will be many total symptoms, for example nervous dysfunction, depression, hypomnesis, absent minded, easy fatigue, insomnia, hectic fever, perspiration and sexual hypofunction, bone mineral density minimizing, anxious state of mind, headache, dizziness, inappetence and abdominal obesity etc. and more symptoms.Can carry out general description by climacteric syndrome to these symptoms.The traditional Chinese medical science thinks and occurs that climacteric syndrome is due to due to deficient five internal organs, insufficiency of vital energy and blood, especially should the kidney invigorating.
The climacteric syndrome of middle-aged and elderly people is a kind of chronic disease that affects the quality of life latter half of one's life.Medically, climacteric refers to the stage changing from the middle age to old age, and general women was at 45 years old～55 years old, and male is 45 years old～65 years old.Concerning women, menopause is that of Women’s climacteric indicates the most significantly, and still, menopause and climacteric are not same concepts, and climacteric should be the summation of " premenopause ", " menopause ", " postmenopause ".Except menopause, Women’s climacteric also has following physiological change more or less: hyposexuality, sexual life discomfort or pain; Emotional, temperish; Depressed, sometimes suspicious; Insomnia and dreamful sleep, hypomnesis etc.Female dimacteric syndrome refers to the light or heavy syndrome taking autonomic nervous dysfunction as master that women occurred climacteric.Clinical manifestation is the confusion of the menstrual cycle, hectic fever, flushing, perspiration and spirit, nervous symptoms.And concerning male, involutional mark is mainly psychentonia or depression, it is tired to be easy to, degradation series of symptoms under hypomnesis, absent minded, insomnia, hectic fever, perspiration, libido.Comparatively speaking, the syndrome of male climacteric syndrome is fewer than women's, because andropausal androgen reduces, is a process slowly.
Chinese traditional treatment climacteric syndrome, mainly adopts the method for determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs.Carry out prescriptions according to different symptoms, taking women as example, in general, mainly being divided into three type opinions controls: (one) syndrome of deficiency of kidney yin: clinical manifestation is menoxenia, and menstrual cycle shortens, and measures less or measures many, or collapse or leak, dizziness, tinnitus, buccal paroxysmal is warmed, perspires, and soreness of waist and knee joint, heel pain, or xerosis cutis, xerostomia constipation, oliguria yellow skin, the few tongue of red tongue, thready and rapid pulse.Prescription is general by Bolus as a Kidney-Yin-Tonic and ERZHI WAN.If there is the diseases such as binocular dryness, add and subtract with QIJU DIHUANG WAN; If vexed not peaceful, insomnia and dreamful sleep, with lilii and Rehmanniae Decoction or GANMAI DAZAO TANG and Chinese goldthread colla corii asini decoction plus-minus.(2) syndrome of deficiency of kidney-YANG: clinical manifestation is menorrhagia, lethargy, complexion is gloomy, back cold type of pain, clear urine in large amounts, nocturia frequency, or puffiness of the face and limbs, thin white fur of tongue, a little less than deep-thready pulse.Prescription is added and subtracted with Yougui Wan, the kidney-Yang-Reinforcing Bolus.(3) all deficiency syndrome of kidney yin sun: clinical manifestation is menoxenia, and dizziness and tinnitus is forgetful, back cold type of pain, light red tongue, thin fur, deep and weak pulse.Prescription is general by ERXIAN TANG and ERZHI WAN.Conventional Chinese patent medicine can be added and subtracted according to symptom, as obvious in the symptom of suffering from a deficiency of the kidney, and just selects the Dihuang Wan class Chinese patent medicines such as LIUWEI DIHUANG WAN, QIJU DIHUANG WAN, MAIWEIDIHUANGWAN, ZHIBAI DIHUANG WAN, Rehmanniae Bolus of Eight Ingredients; Insomnia, irritated class symptom is obvious, just selects the Anshen Wan class Chinese patent medicines such as Cinnabar Sedative Pill, mind-easing tonic bolus with arborvitate seed, Tianwang Buxin Dan, the will of calming the nerves ball; The obvious person of depressive symptom, can select JIAWEI XIAOYAO SAN class Chinese patent medicine.Also have in addition the female precious ball that filters out of Tongrentang from first ancient Chinese medicine recipes up to ten thousand, can be applicable to male while there is menopause syndrome.
Gastric ulcer:
Gastric ulcer refers to that the inflammatory necrosis sexually transmitted disease (STD) betiding between cardia and pylorus becomes, because stress state, the stimulation of chemical factors and the infection of part pathogen of body all can cause gastric ulcer.Gastric ulcer belongs to the category such as gastric abscess, feeling of fullness in motherland's medical science, and this disease course of disease is long, easily outbreak repeatedly.(Zhu Bin, selection and the effect analysis of Chinese traditional treatment gastric ulcer method, tcm clinical practice research, 2011,3(18): 121)
Find by Long-term Clinical Observation, chronic gastric ulcer is generally because spleen sun is on the decline, due to deficiency of QI in middle-JIAO, the dialectical syndrome of deficient cold of spleen and stomach that surely belongs to, and treatment is taken in taking gas in replenishing vital QI with drugs of warm nature as main, give Huangqi Jianzhong Tang, basic side is: the Radix Astragali, Ramulus Cinnamomi, the Radix Paeoniae Alba, Rhizoma Zingiberis Recens, Radix Glycyrrhizae Preparata, Fructus Jujubae, maltose.
The existence of above-mentioned disease, treatment need to be nursed one's health for a long time, and can treat above-mentioned disease without unified formula.
Therefore, also need further to develop a kind of Chinese medicine composition of new health care.
Summary of the invention
In order to overcome the deficiencies in the prior art, the object of this invention is to provide a kind of benefiting vital QI and blood, yin nourishing Yiyang, raising immunity, resisting fatigue, thrombotic Chinese medicine composition of inhibition of health care.
Another object of the present invention is to provide the preparation method of this Chinese medicine composition.
A further object of the present invention is to provide the health preserving wine containing this Chinese medicine composition.
An also object of the present invention is to provide the application of this Chinese medicine composition.
Chinese medicine composition of the present invention is and the human body attribute nutrient source of harmony mutually; this nutrient source is to the vital organs of the human body both nutritious relief effect; there are again positioning function and the effect of recovery, improvement, the enhancing vital organs of the human body; make human body to equilibrium between yin and yang; QI and blood is not lost and with smooth, the state of blood supply quality normalization develops.
A kind of benefiting vital QI and blood provided by the invention, yin nourishing Yiyang, raising immunity, resisting fatigue, the thrombotic Chinese medicine composition of inhibition, the Chinese medicine that it contains following weight portion: Radix Rehmanniae Preparata 10-30 part, Radix Angelicae Sinensis 5-15 part, Radix Codonopsis 10-30 part, Fructus Lycii 5-10 part, Radix Morindae Officinalis 3-10 part.
Preferably, the Chinese medicine that described Chinese medicine composition contains following weight portion: Radix Rehmanniae Preparata 15-25 part, Radix Angelicae Sinensis 5-10 part, Radix Codonopsis 15-25 part, Fructus Lycii 5-10 part, Radix Morindae Officinalis 7-10 part.
Further preferably, the Chinese medicine that described Chinese medicine composition contains following weight portion: 20 parts of Radix Rehmanniae Preparata, 10 parts of Radix Angelicae Sinensis, 20 parts of Radix Codonopsis, 8 parts of Fructus Lycii, 10 parts of Radix Morindae Officinaliss.
Described Chinese medicine composition also contains following Chinese medicine: Radix Ophiopogonis, its consumption is 10-20 part, is preferably 15-18 part, more preferably 15 parts.
In above-mentioned Chinese medicine composition:
Described weight portion can be the known unit of weights of field of medicaments such as μ g, mg, g, kg, can be also its multiple, as 1/10,1/100,10 times, 100 times etc.
Described Radix Morindae Officinalis is stir-baking RADIX MORINDAE after sprinking salt solution sky.
The present invention also provides the preparation method of above-mentioned Chinese medicine composition, and the method comprises the following steps: take each Chinese medicine ingredients according to proportioning, 30-60 minute is then soaked in water Chinese medicine, amount of water be Chinese medicine gross weight 6-10 doubly, then boil the little fire state of boiling after boiling, decoct 1-3 hour, cross leaching filtrate, then add Chinese medicine gross weight 6-8 water doubly, decoct 1-3 hour, filter, merge filtrate twice, concentrated, to obtain final product.
Preferably, said method comprises the following steps: take each Chinese medicine ingredients according to proportioning, 30-60 minute is then soaked in water Chinese medicine, amount of water be Chinese medicine gross weight 8-10 doubly, then boil the little fire state of boiling after boiling, decoct 2 hours, cross leaching filtrate, then add Chinese medicine gross weight 6-8 water doubly, decoct 1.5-2 hour, filter, merge filtrate twice, be evaporated to dryly, to obtain final product.
The present invention also provides a kind of health preserving wine, made by following methods: take each Chinese medicine ingredients according to proportioning, then 30-60 minute is soaked in water Chinese medicine, amount of water is 6-10 times of Chinese medicine gross weight, then boil, the little fire state of boiling after boiling, decoct 1-3 hour, cross leaching filtrate, add again Chinese medicine gross weight 6-8 water doubly, decoct 1-3 hour, be preferably 1.5-2 hour, filter, merge filtrate twice, be concentrated into be equivalent to crude drug weight 1-2 doubly, obtain Chinese medicine composition decoction, then Chinese medicine composition decoction and white spirit mixing, the volume ratio of Chinese medicine composition decoction and this Chinese liquor is 1:(1-3), health preserving wine.
Described Chinese liquor, is high quality liquor, especially more suitable with aromatic Chinese spirit.Its number of degrees are for being less than or equal to 60 degree, as 53 degree, 42 degree, 38 degree etc.
In described health preserving wine, every ml is containing 0.16-0.5g crude drug.
The dose of described health preserving wine is no more than 100ml and is advisable every day.
The present invention also provides a kind of preparation containing above-mentioned Chinese medicine composition, is made separately or is made up of this Chinese medicine composition and pharmaceutically acceptable carrier by this Chinese medicine composition.
Described pharmaceutically acceptable carrier refers to the pharmaceutical carrier of pharmaceutical field routine, is selected from one or more in filler, binding agent, disintegrating agent, lubricant, solubilizing agent, suspending agent, wetting agent, pigment, essence, solvent, surfactant or correctives.
Described filler is selected from starch, pregelatinized Starch, dextrin, glucose, sucrose, lactose, lactose, microcrystalline Cellulose, mannitol, sorbitol or xylitol, preferably sorbitol, microcrystalline Cellulose, lactose or pregelatinized Starch;
Described disintegrating agent is selected from cross-linking sodium carboxymethyl cellulose, polyvinylpolypyrrolidone, low-substituted hydroxypropyl cellulose, carboxymethyl starch sodium or starch, preferably polyvinylpolypyrrolidone, low-substituted hydroxypropyl cellulose or carboxymethyl starch sodium;
Described lubricant is selected from magnesium stearate, Pulvis Talci, micropowder silica gel, PEG4000, PEG6000, sodium laurylsulfate, preferably magnesium stearate, Pulvis Talci;
Described binding agent is selected from sodium carboxymethyl cellulose, hydroxypropyl methylcellulose, ethyl cellulose, polyvidone, starch slurry, sucrose, Icing Sugar, rubber cement, gelatin, Polyethylene Glycol, preferably hydroxypropyl methylcellulose, polyvidone;
Described solubilizing agent is selected from sodium hydroxide, potassium hydroxide, sodium bicarbonate, meglumine, 1B, L-arginine, preferably sodium hydroxide, meglumine;
Described suspending agent is selected from micropowder silica gel, Cera Flava, cellulose, solid polyethylene glycol;
Described wetting agent is selected from glycerol, tween 80, ethyoxyl castor oil hydrogenated or lecithin;
Described solvent is selected from ethanol, liquid polyethylene glycol, isopropyl alcohol, tween 80, glycerol, propylene glycol or vegetable oil, and described vegetable oil is selected from soybean oil, Oleum Ricini, Oleum Arachidis hypogaeae semen, mediation wet goods;
Described surfactant is selected from smooth or Polysorbate (tween) of dodecylbenzene sodium sulfonate, stearic acid, Pluronic F68, fatty acid Pyrusussuriensis etc.;
Described correctives is selected from aspartame, Sucralose, essence, steviosin, acesulfame potassium, citric acid or saccharin sodium.
Described preparation is decoction, tablet, capsule, pill or oral liquid.
The present invention also provides the application of above-mentioned Chinese medicine composition in the medicine of preparing benefiting qi and nourishing blood, adjusting negative and positive, and application is specifically related to regulate immunity, and resisting fatigue, prevents and treats climacteric syndrome, prevent and treat nine diseases (deficiency of the kidney yin, insufficiency of kidney-YANG, kidney insufficiency, the hepatic and renal YIN deficiency, deficiency of spleen-YANG and kidneyYANG, deficiency of heart-yin, deficiency of heart-YANG, depression of liver-QI, disarmony between the heart and kidney), improve and strengthen function of five internal organs, prevent and treat thrombosis, anti-blood pressure, blood fat, blood sugar increasing, treatment lumbago and skelalgia, insomnia, forgetful, the fields such as sexual hypofunction.
Benefiting vital QI and blood of the present invention, yin nourishing Yiyang, raising immunity, resisting fatigue, the thrombotic Chinese medicine composition advantage of inhibition are:
1, the generation of human body diseases, normally there is Close relation with inherited genetic factors, physical factor, trophic factor, infection factor, chemical factor, Hormone Factors, medicine factor and immunity and cell situation factor, also relevant with various diseases factor (such as disease factors such as diabetes) in addition, by above etc. factors disrupt the vital organs of the human body normal function so that cause the generation of human body diseases.In the five internal organs (liver, the heart, spleen, lung, kidney), an organ function reduction or destroyed, will tie down other four internal organs.For example, nephropathy can increase the burden of liver, lung, spleen, the heart, and other organs is also like this.The result that organ function is destroyed, is first blood supply insufficiency, moreover must on nine diseases (deficiency of the kidney yin, insufficiency of kidney-YANG, kidney insufficiency, the hepatic and renal YIN deficiency, deficiency of spleen-YANG and kidneyYANG, deficiency of heart-yin, deficiency of heart-YANG, depression of liver-QI, disarmony between the heart and kidney), show.
The present invention is under instruction of Chinese Medicine theory, and in accordance with the meridian distribution of property and flavor of medical material, function cures mainly, and nontoxic Chinese crude drug is used in compatibility potentiation and pharmacological action, has invented satisfied two groups of (five tastes, Six-element) Chinese medicine compositions without disconnection network compatibility synergistic device.Returning through being conscience spleen lung kidney stomach of these two groups of Chinese crude drugs.First every group of this Chinese medicine composition play nutrition relief effect to the five internal organs, play adjusting negative and positive to balance, benefiting vital QI and blood arrives and is smooth, and then has produced the effect of improving enhancing the five internal organs positioning functions, also improving blood supply quality, suppress the cardiovascular disease aspects such as thrombosis and produce effect simultaneously.Very make QI and blood Tianjin spirit normalization of people.
2, in Chinese medicine composition provided by the invention, comprise nine compatibility synergistic function lines and Radix Rehmanniae Preparata, Radix Angelicae Sinensis, the thrombotic special functional line of Radix Codonopsis three compatibility potentiation inhibition, specific as follows:
1) Radix Morindae Officinalis is joined Radix Rehmanniae Preparata: Radix Morindae Officinalis is longer than warming the kidney to activate YANG; Radix Rehmanniae Preparata is good at nourishing YIN and benefiting blood.Two medicine compatibilities, can strengthen warming the kidney to activate YANG, the effect of nourishing YIN and benefiting blood.Be applicable to impotence due to deficiency of the kidney, premature ejacuation emission etc.
2) Radix Morindae Officinalis is joined Radix Codonopsis: Radix Morindae Officinalis is longer than kidney warming and yang invigorating; Radix Codonopsis is good at air making-up and spleen enlivening.Two medicine compatibilities, can strengthen warming the kidney to activate YANG, the effect of air making-up and spleen enlivening.Be applicable to male dificiency of kidney sexual impotence, woman's yang deficiency is infertile etc.
3) Radix Codonopsis is joined Radix Rehmanniae Preparata: Radix Codonopsis is sweet flat, is longer than and strengthens the spleen and stomach, biochemical essence and blood; The sweet tepor of Radix Rehmanniae Preparata, is good at the YIN nourishing of enriching blood, and beneficial essence is filled out marrow.Two medicine compatibilities, can strengthen the effect of qi-supplementing, blood-engendering.Shallow complexion due to being applicable to that QI and blood is two and losing, dizzy cardiopalmus, weak weak, body and the spirit deficiency etc.
4) Radix Angelicae Sinensis is joined Radix Rehmanniae Preparata: Chinese angelica blood supplementing and energy promoting the circulation of blood regulating menstruation; Radix Rehmanniae Preparata is enriched blood and can beneficial essence be filled out marrow.Two medicine compatibilities, can strengthen the effect of the yin nourishing of enriching blood.Be applicable to blood deficiency and have all diseases of the deficiency of YIN concurrently.
5) Radix Codonopsis is joined Radix Angelicae Sinensis: Radix Codonopsis is longer than invigorating the spleen and benefiting QI; Radix Angelicae Sinensis is good at nourishing blood and blood.Two medicine compatibilities, can strengthen the effect of benefiting qi and nourishing blood.Be applicable to all diseases of internal injury insufficiency of vital energy and blood, as dizzy, weak, deficiency of QI with disinclination to talk etc.
6) Fructus Lycii is joined Radix Rehmanniae Preparata: Fructus Lycii is longer than nourishing kidney yin, enriching kidney essence; Radix Rehmanniae Preparata is good at the YIN nourishing of enriching blood, and beneficial essence is filled out marrow.Two medicine compatibilities, can strengthen nourishing kidney yin, and beneficial essence is filled out the effect of marrow.Be applicable to deficiency of kidney yin, the essence insufficiency of blood that declines, soreness of the waist and knees, wan and sallow looking, impotence and seminal emission etc.
7) Fructus Lycii is joined Radix Angelicae Sinensis: Fructus Lycii is the moon of invigorating the liver and kidney both, has again the merit nourishing blood; Chinese angelica blood supplementing and blood.Two medicine compatibilities, can have the effect of blood-supplementing blood-nourishing.Be applicable to puerperal exposure to wind asthenia and damage, limbs pain, mind fidgets due to deficiency, loss of appetite etc.
8) Radix Codonopsis is joined Radix Ophiopogonis: Radix Codonopsis is sweet flat, and invigorating the spleen to benefit the lung, promotes the production of body fluid and nourish blood; Radix Ophiopogonis is sweet, be slightly cold, nourishing YIN and moistening the lung, reinforcing stomach reg fluid.Two medicine compatibilities, can strengthen the effect of tonifying QI to produce body fluid.Be applicable to heat impairing vital QI the moon, the large consumption of body fluid, the faint pulse etc. of having a guilty conscience.
9) Fructus Lycii is joined Radix Ophiopogonis: Fructus Lycii is flat and not hot, has the energy of moisturizing fire processed; The sweet Han Zhirun of Radix Ophiopogonis, has the use of reinforcing stomach reg fluid.Two medicine compatibilities, can have nourishing the liver and kidney, the effect of reinforcing stomach reg fluid.Be applicable to the sliding number of urine, xerostomia is vexed, xerosis cutis, and waist knee joint disappears carefully, gradually extremely unable etc.
Chinese medicine composition of the present invention return through: have four kinds to return warp to liver, have three kinds to return warp to kidney, with strengthen realize The liver and the kidney have a common source, the function of essence and blood alternate.
10) Radix Rehmanniae Preparata, Radix Angelicae Sinensis, the potentiation of Radix Codonopsis three compatibility suppress thrombotic pharmacological action, and three all has the thrombotic function of inhibition.In this network compatibility, allotted above 3), 4), 5) three have without the potentiation of disconnection network compatibility and suppress thrombotic functional line.Radix Rehmanniae Preparata, Radix Angelicae Sinensis, Radix Codonopsis without disconnection compatibility, formed to strengthen and suppressed thrombotic efficacy effect.Radix Rehmanniae Preparata has inhibitory action to platelet aggregation, and antithrombase is had to activation, and fibrinolytic system is had to activation, thereby can suppress the formation of Intravascular Thrombus.In Radix Angelicae Sinensis, Rhizoma Ligustici lactone has the effect of anticoagulant, and Radix Angelicae Sinensis and ferulic acid thereof have obvious anti thrombotic action.Radix Codonopsis has the thrombotic effect of inhibition.So the present invention is very remarkable to suppressing the clinical drug effect of thrombosis.
3, Chinese medicine composition provided by the invention, its raw material is all the tonification medical material that there is no toxic and side effects, and is all the medical material with Nutrition.These Chinese medicines are returned through being all again GUIXIN liver spleen lung kidney stomach, so, conscience spleen lung kidney stomach has been played to nutrition relief effect.The function of these drug matching potentiation is that conscience spleen lung kidney stomach own job positioning function is needed, thereby, the rest health preserving enhancement function of conscience spleen lung kidney stomach is played regulatory role.This Chinese medicine composition is to form without disconnection network compatibility potentiation method compatibility with the present invention, like this, expection effect is consistent with clinical efficacy height, people have been obtained to be relieved vital organs of the human body nutrition with the present invention, strengthen the adjusting source of positioning function, both can improve and strengthen the normalization level of people's vital organs of the human body function, can help to realize the blood of human body being supplied with to qualified, promote to realize systemic circulation, the all normal health-physical fitness of partial circulating, prevent and treat thrombosis from root, prevent and treat hypertension, hyperlipidemia, hyperglycemia, the disease of control treating cardiac and cerebral vascular diseases, also can prevent and treat nine disease (deficiency of the kidney yin, insufficiency of kidney-YANG, kidney insufficiency, the hepatic and renal YIN deficiency, deficiency of spleen-YANG and kidneyYANG, deficiency of heart-yin, deficiency of heart-YANG, depression of liver-QI, disarmony between the heart and kidney) and the female climacteric syndrome that causes, also just can improve immunity, resisting fatigue, certainly also just solved because of blood deficiency can not nourishing muscle and tendon, the disease of the lumbago and skelalgia class that stagnation of blood stasis meridians cause, thereby reach equilibrium between yin and yang, not empty, QI and blood is sufficient and smooth, sexual life is just had to the material nutrition condition of essence and blood abundance, prostate can be because of the not smooth hypertrophy of blood supply, cause dysuria.Meanwhile, to the insomnia forgetfulness causing because of " nine diseases ", hypomnesis, stomach discomfort all has remarkable result.In addition, Six-element Chinese medicine provided by the invention, except having the effect of Chinese medicine of the five flavours, can also be alleviated the symptom of gastric ulcer.
More than discuss and all can be confirmed by following detailed description of the invention.
Detailed description of the invention
Following examples are used for illustrating the present invention, but are not used for limiting the scope of the invention.
Embodiment 1: Chinese medicine composition decoction
1, composition: Fructus Lycii 100g, Radix Rehmanniae Preparata 250g, Radix Angelicae Sinensis 80g, Radix Codonopsis 250g, stir-baking RADIX MORINDAE after sprinking salt solution 90g, Radix Ophiopogonis 180g.(adding up to 950g)
2, preparation method: take each Chinese medicine ingredients according to proportioning, then Chinese medicine is soaked in water 40 minutes, amount of water is 8 times (being 7600g) of Chinese medicine gross weight, then boil, after boiling, the little fire state of boiling, decocts 2 hours, cross leaching filtrate, add the water (being 5700g) of 6 times of Chinese medicine gross weights, after boiling, the little fire state of boiling, decocts 2 hours again, filter, merge filtrate twice, be evaporated to 950ml, obtain Chinese medicine composition decoction (every ml is containing crude drug 1g).
Embodiment 2: Chinese medicine composition decoction
1, composition: Fructus Lycii 80g, Radix Rehmanniae Preparata 200g, Radix Angelicae Sinensis 100g, Radix Codonopsis 200g, stir-baking RADIX MORINDAE after sprinking salt solution 100g.(adding up to 680g)
2, preparation method: take each Chinese medicine ingredients according to proportioning, then Chinese medicine is soaked in water 40 minutes, amount of water is 10 times (being 6800g) of Chinese medicine gross weight, then boil, after boiling, the little fire state of boiling, decocts 2 hours, cross leaching filtrate, add the water (being 5440g) of 8 times of Chinese medicine gross weights, after boiling, the little fire state of boiling, decocts 1.5 hours again, filter, merge filtrate twice, be evaporated to 1360ml, obtain Chinese medicine composition decoction (every ml is containing crude drug 0.5g).
Embodiment 3: health preserving medicated wine preparation
1, composition: Fructus Lycii 100g, Radix Rehmanniae Preparata 250g, Radix Angelicae Sinensis 80g, Radix Codonopsis 250g, stir-baking RADIX MORINDAE after sprinking salt solution 90g.(adding up to 770g)
2, preparation method:
Take each Chinese medicine ingredients according to proportioning, then Chinese medicine is soaked in water 40 minutes, amount of water is 8 times of Chinese medicine gross weight, then boil, after boiling, the little fire state of boiling, decocts 2 hours, cross leaching filtrate, add the water of 6 times of Chinese medicine gross weights, after boiling, the little fire state of boiling, decocts 2 hours again, filter, merge filtrate twice, be evaporated to 1155ml, obtain Chinese medicine composition decoction (every ml is containing crude drug 0.67g).
Chinese medicine composition decoction and 53 degree strong, colourless liquor distilled from sorghum are blent, and Chinese medicine composition volume can be 1:1 with the ratio of this Chinese liquor volume, health preserving wine, every ml is containing 0.335g crude drug.
3, taking of health preserving wine: every consumption per day is no more than 100ml and is advisable.
Embodiment 4: health preserving medicated wine preparation
1, composition: Fructus Lycii 80g, Radix Rehmanniae Preparata 200g, Radix Angelicae Sinensis 100g, Radix Codonopsis 200g, stir-baking RADIX MORINDAE after sprinking salt solution 100g.（680g）。
2, preparation method:
Prepare Chinese medicine composition decoction according to the method for embodiment 2.
Chinese medicine composition decoction and 39 degree aromatic Chinese spirits are blent, and Chinese medicine composition volume can be 1:1 with the ratio of this Chinese liquor volume, health preserving wine, every ml is containing 0.25g crude drug.
3, taking of health preserving wine: every consumption per day is no more than 100ml and is advisable.
Embodiment 5: tablet (following dosage is 10 doses of consumptions)
1, composition: Fructus Lycii 80g, Radix Rehmanniae Preparata 200g, Radix Angelicae Sinensis 80g, Radix Codonopsis 200g, stir-baking RADIX MORINDAE after sprinking salt solution 80g.(adding up to 640g)
2, preparation method: above-mentioned Chinese medicine is soaked 30 minutes, the water surface is higher than raw material Chinese medicine, amount of water is 8 times of total dose, the little fire state of boiling after boiling, maintain liquid level higher than raw material Chinese medicine height, decoct two hours, cross leaching filtrate, add again the water of 6 times of total doses, after boiling, the little fire state of boiling, maintains liquid level higher than raw material Chinese medicine height, decocts two hours, filter and merge filtrate twice,, pulverize to dry cream through concentrating under reduced pressure (pressure 0.06MPa, 65 DEG C of temperature), obtain 166.4g Chinese medicine composition (yield is 26%, and every g is containing crude drug 3.85g).
3, tablet: 100g Chinese medicine composition mixes with 50g starch, crosses 60 mesh sieves, granulates, dry, then adds 4g magnesium stearate, and tabletting, obtains tablet.
Embodiment 6: capsule
1, composition: Fructus Lycii 100g, Radix Rehmanniae Preparata 250g, Radix Angelicae Sinensis 50g, Radix Codonopsis 150g, stir-baking RADIX MORINDAE after sprinking salt solution 100g.(adding up to 650g)
2, preparation method: above-mentioned Chinese medicine is soaked 50 minutes, the water surface is higher than raw material Chinese medicine, amount of water is 8 times of total dose, the little fire state of boiling after boiling, maintain liquid level higher than raw material Chinese medicine height, decoct two hours, cross leaching filtrate, add again the water of 6 times of total doses, after boiling, the little fire state of boiling, maintains liquid level higher than raw material Chinese medicine height, decocts two hours, filter and merge filtrate twice,, pulverize to dry cream through concentrating under reduced pressure (pressure 0.06MPa, 65 DEG C of temperature), obtain 149.5g Chinese medicine composition (yield is 23%, and every g is containing crude drug 4.35g).
3, capsule: Chinese medicine composition is crossed 300 mesh sieves, takes Chinese medicine composition 100g, adds the magnesium stearate of gross weight 2%, is distributed into capsule.
Embodiment 7: pill
1, composition: Fructus Lycii 70g, Radix Rehmanniae Preparata 150g, Radix Angelicae Sinensis 70g, Radix Codonopsis 180g, stir-baking RADIX MORINDAE after sprinking salt solution 90g.(adding up to 560g)
2, preparation method: above-mentioned Chinese medicine is soaked 60 minutes, the water surface is higher than raw material Chinese medicine, amount of water is 8 times of total dose, the little fire state of boiling after boiling, maintain liquid level higher than raw material Chinese medicine height, decoct two hours, cross leaching filtrate, then add the water of 6 times of total doses, the little fire state of boiling after boiling, maintain liquid level higher than raw material Chinese medicine height, decoct two hours, filter and merge filtrate twice, through concentrating under reduced pressure (pressure 0.06MPa, 65 DEG C of temperature) to dry cream, obtain 142.6g Chinese medicine composition (yield is 25.5%, and every g is containing crude drug 3.93g).
3, pill: water is general is ball, coating.
Embodiment 8: oral liquid
1, composition: Fructus Lycii 50g, Radix Rehmanniae Preparata 200g, Radix Angelicae Sinensis 100g, Radix Codonopsis 160g, stir-baking RADIX MORINDAE after sprinking salt solution 70g.(adding up to 580g)
2, preparation method: above-mentioned Chinese medicine is soaked 45 minutes, the water surface is higher than raw material Chinese medicine, amount of water is 8 times of total dose, the little fire state of boiling after boiling, maintain liquid level higher than raw material Chinese medicine height, decoct two hours, cross leaching filtrate, then add the water of 6 times of total doses, the little fire state of boiling after boiling, maintain liquid level higher than raw material Chinese medicine height, decoct two hours, filter merging filtrate, being concentrated into relative density is 1.17(70 DEG C) clear paste, obtain 174g Chinese medicine composition (yield is 30%, and every g is containing crude drug 3.33g).
3, oral liquid: Chinese medicine composition 100g adds ethanol, makes to reach 65% containing alcohol amount, with sodium hydroxide adjusting pH to 6.8, leave standstill 36 hours, filter, in filtrate, add ethanol, make to reach 75% containing alcohol amount, leave standstill 24 hours, filter, filtrate recycling ethanol, to without alcohol taste, is heated to micro-boiling 15 minutes, stir evenly, add water to 1000ml, stir evenly, filter, embedding, obtains oral liquid (every ml is containing 0.333g crude drug).
Following experimental example is that product of the present invention carries out in the time of clinical experiment.
Experimental example 1: grandson so-and-so (man, 76 years old)
1, the state of an illness: heart is put three supports, puts a support on lower limb; Blood supply is poor, has thrombosis; Difficult dormancy, has horrible nightmares whole night, feel fatigue, and have a head like a sieve; After squatting down, need to just can stand by other supporters.
2, take embodiment 1 decoction, every day 100ml, 30 days, result was as follows:
Take medicine 6 days, sleep becomes normal;
Take medicine 12 days, memory is obviously improved;
Take medicine 24 days, after squatting down, do not hold up thing to have stood up, cannot not feel tiredly;
Take medicine 30 days, it is clear-headed that brains becomes, resourceful, and stomach is comfortable, carries out heart DSA trunk DSA check through front three hospital with digital subtraction angiography, and coronary stricture position tails off, and thrombosis symptom is alleviated to some extent.
Experimental example 2: Lee so-and-so (man, 57 years old)
1, the state of an illness: diagnose with PET-CT through front three hospital, suffer from congenital cerebral infarction.After older, cerebral blood flow is slack-off, and cerebral blood supply insufficiency causes brain discomfort, and arm, hands are numb unable.Doctor advised is seen its development process to select treatment means.There is serious feeling of fatigue.
2, treatment and result: take embodiment 2 decoctions, every day, 100ml, took 60 days continuously, and result is as follows:
Take medicine 30 days, the uncomfortable situation of brains lightens, and numbness of hand situation alleviates;
Take medicine 60 days, brains is substantially without sense of discomfort, and arm, hands be without picotement, and has dynamics; Can normally work, tired disappearance, through PET-CT check diagnosis for front three hospital, cerebral blood flow has accelerated, and cerebral blood supply is normal, not ischemia of brain.
Experimental example 3: car so-and-so (female, 60 years old)
1, the state of an illness: carotid artery has 5 unit ecchymosiss; Lumbar intervertebral disc has and comes off; General weakness, lumbago and skelalgia is serious, the work of cannot doing chores; Within 10 years, there is no libido.
2, treatment and result: take embodiment 2 decoctions, every day 100ml, continuous 24 days, result was: carotid artery ecchymosis is kept to 3 units by 5 units, and ecchymosis obviously reduces; Lumbago and skelalgia obviously alleviates, and can do housework; Tired disappearance; Libido is hoped to be increased.
Experimental example 4: Yao so-and-so (female, 74 years old)
1, the state of an illness: sleep very poor, appetite is very poor, lassitude loin and legs.
2, treatment and result: take embodiment 7 pills, every day, 36g(referred to containing crude drug amount), divide and take for three times, continuous 6 days, sleep quality improved, appetite strengthens, shape and color takes a turn for the better.
Experimental example 5: dragon so-and-so (man, 76 years old)
1, the state of an illness: the five internal organs have multiple chronic disease; Appetite extreme difference; Meteorism can not arranged; Tired.
2, treatment and effect: take embodiment 6 capsules, every day, 36g(referred to containing crude drug amount), divide and take for three times, to take 6 days, result is:
Take 2 days, Meteorism discharges; Appetite increases to original 3 times, and shape and color improves, and fatigue alleviates.
Experimental example 6: desert so-and-so (female, 50 years old)
1, the state of an illness: legs and feet are sent out cool for many years, feel feels cold in bed; QI and blood is two loses, shape and color deficiency.
2, treatment and effect: take embodiment 8 oral liquids, every day, 60ml(was 20g containing crude drug amount), divide and take for three times, take continuously its effect 6 days:
First day is taken after three times, felt the same day foot not cold improved microcirculation, improved blood supply quality;
Take medicine after 6 days, microcirculation significantly improves, and shape and color has also improved.
Experimental example 7: Zhang (female, 37 years old)
1, the state of an illness: whole body has rheumatism sense of discomfort, trick action has sticky feeling; Fatigue, wan and sallow looking.
2, treatment and effect: take embodiment 5 tablets, every day the 30g(30g dose of making a living), point take for three times, take continuously after 6 days, whole body is felt to unfold, trick has been active in one's movements; Improve blood supply quality, not tired and cannot not describe wan and sallowly.
Experimental example 8: field so-and-so (man, 73 years old)
1, the state of an illness: libido obviously goes down; Beard is sent out eyebrow and is accelerated to bleach; Night sweat is vexed, and physical ability obviously declines.
2, treatment and effect: take embodiment 6 capsules, every day the 36g(36g dose of making a living), point take for three times, take continuously after 30 days, libido is normal, it is black that beard and hair turns, physical ability is normal.
Experimental example 9: Wang (female, 42 years old)
1, the state of an illness: stomach upset, vexed, fatigue, learning memory declines.
2, treatment and effect: take embodiment 7 pills, every day the 36g(36g dose of making a living), point take for three times, take continuously after 6 days, stomach discomfort disappears, stomach upset sense disappears, heart calmness, not tired, memory makes moderate progress.
Experimental example 10: king so-and-so (female, 56 years old)
1, the state of an illness: multiple climacteric syndrome, heart rate is often not normal, describes very wan and sallowly, and memory obviously declines, fatigue, without appetite, vaginal dryness.
2, treatment and effect: take embodiment 2 decoctions, take 100ml every day, take continuously after 20 days, the various symptoms before taking medicine all take an evident turn for the better, and have strengthened enterprise.
Experimental example 11: poplar (man, 46 years old)
1, the state of an illness: prostatic hyperplasia is obvious, urinary tract is not smooth, hyposexuality, waist discomfort.
2, treatment and effect: take embodiment 5 tablets, every day the 36g(36g dose of making a living), point take for three times, take continuously after 10 days, prostatic hyperplasia reduces, urinary tract is unobstructed, sexual life is normal, and waist is without sense of discomfort.
Experimental example 12: Yang (man, 70 years old)
1, the state of an illness: QI and blood is two loses, lumbago and skelalgia is weak weak, has rheumatism.
2, treatment and effect: take embodiment 7 pills, every day the 36g(36g dose of making a living), point take for three times, take continuously after 14 days, energetically, rheumatism alleviates waist lower limb.
Experimental example 13: Zhang (man, 55 years old)
1, the state of an illness: depression of liver-QI, to sigh, failure of the kidney in receiving QI, exhales inhale less more, and emotion irritability is vexed, climacteric syndrome.
2, treatment and effect: take embodiment 7 pills, every day the 36g(36g dose of making a living), point take for three times, take continuously after 18 days, no longer sigh, breathe comfortable gradually, climacteric syndrome anesthesia.
Experimental example 14: revive certain (man, 77 years old)
1, the state of an illness: health is general, takes depressor every day, maintains blood pressure 85-130mmHg.
2, treatment and effect: take embodiment 5 tablets, every day the 30g(30g dose of making a living), point take for three times, take continuously after 14 days blood pressure 80-120mmHg.
Experimental example 15: to certain (female, 54 years old)
1, the state of an illness: have multiple climacteric sense of discomfort.
2, treatment and effect: take embodiment 8 oral liquids, every day, 60ml, divided a secondary to take, and took continuously after 14 days, and female menopause symptoms is felt to alleviate.
Experimental example 16: Zhang (man, 55 years old)
1, the state of an illness: vexed, worried, depressed mood, often to drink sorrow down more anxious, the brain unintelligible state of being everlasting, has climacteric syndrome, fatiguability.
2, treatment and effect: take embodiment 3 health preserving wines, take 100ml every day, take continuously after 10 days, be in a cheerful frame of mind, enterprise strengthens, no longer decadent, thinking is clear, and feeling of fatigue disappears, and energy is abundant than before.
Experimental example 17: Liu so-and-so (man, 55 years old)
1, the state of an illness: vexed difficult dormancy, can fly into a rage without reason, often borrow wine to disappear vexatious more tired, there is climacteric syndrome.
2, treatment and effect: take embodiment 3 health preserving wines, take 100ml every day, take continuously after 10 days, sleep is clearly better, and inter personal contact is improved, mood is improved, and happy and healthy sense increases.
Experimental example 18: king so-and-so (man, 58 years old)
1, the state of an illness: vexed insomnia, there is worried sense, work ungodliness, often drinks sorrow down and more anxious, without appetite, has climacteric syndrome.
2, treatment and effect: take embodiment 4 health preserving wines, take 100ml every day, take continuously after 10 days, calmly, there is satisfied sense, sleep takes a turn for the better, and enterprising, appetite is improved, and energy is than in the past good, and favorite is drunk this wine.
Experimental example 19: Hu (man, 52 years old)
1, the state of an illness: be often only in and drink, without appetite, do not eat staple food, poor physical capacity, deficient in energy state, has climacteric syndrome.
2, treatment and effect: take embodiment 4 health preserving wines, take 100ml every day, take continuously after 10 days, appetite increases, energy, than in the past good, has happy feeling to work, has satisfied sensation.
Experimental example 20: Lee so-and-so (man, 52 years old)
1, the state of an illness: almost monthly have flu in various degree, immunity is poor.
2, treatment and effect: take embodiment 2 decoctions, take 100ml every day, take continuously after 14 days, not yet occur over the past half year flu, immunity obviously strengthens.
Experimental example 21: Hu (man, 72 years old)
1, the state of an illness: winter normal easy catching a cold, immunity is poor.
2, treatment and effect: take embodiment 2 decoctions, take 100ml every day, take continuously after 14 days, do not catch a cold through four months winters, immunity strengthens.
Experimental example 22: Cui so-and-so (female, 57 years old)
1, the state of an illness: gynecologic surgery, easy catching a cold, immunity is poor.
2, treatment and effect: take embodiment 2 decoctions, take 100ml every day, take continuously after 14 days, do not catch a cold half a year, immunity increases.
Experimental example 23: Cao (man, 68 years old)
1, the state of an illness: fatiguability, energy deficiency, with gastric ulcer, feel run-down.
2, treatment and effect: take embodiment 1 decoction, take 100ml every day, take continuously after 6 days, feeling of fatigue disappears, and has energy, and weak sense disappears, and gastric ulcer symptom is alleviated gradually.
Experimental example 24: Zhang (female, 54 years old)
1, the state of an illness: fatiguability, energy deficiency, feel run-down, asthenia.
2, treatment and effect: take embodiment 1 decoction, take 100ml every day, take continuously after 6 days, feeling of fatigue disappears, and has had energy, and weak sense disappears, and asthenia also disappears.
Experimental example 25: climacteric syndrome
1, include and 35-80 year have the patient of climacteric syndrome in various degree, each 175 people of men and women,
2, experimental technique: be divided into 7 groups, every group of 50 people, its medical material forms with reference to embodiment 1,3-8 each component, is made into health preserving wine, and its concrete preparation method, all with reference to embodiment 3, is taken 100ml every day, takes continuously 3 days.
3, therapeutic outcome: everyone feels that health preserving wine taste is fine is enjoyed after drinking very much, makes us satisfied, and energy foot is not tired.
Experimental example 26: climacteric syndrome
1, include the patient who has climacteric syndrome in various degree to have stomach discomfort concurrently in 35-80 year, each 175 people of men and women.
2, experimental technique: be divided into 7 groups, every group of 50 people, its medical material forms with reference to respectively component of embodiment 1,3-8, is made into health preserving wine, and its concrete preparation method, all with reference to embodiment 3, is taken 100ml every day, takes continuously 3 days.
3, therapeutic outcome: everyone feels that health preserving wine taste is fine is enjoyed after drinking very much, makes us satisfied, energy foot, and not tired, stomach discomfort alleviates, and very person disappears; Take the experimental group of embodiment 1, stomach discomfort improves particularly evident.
Experimental example 27: climacteric syndrome, companion's immunity reduces
1, according to male 35-80 year, female 35-60 year, there is the symptom of climacteric syndrome, and the patient of hypoimmunity, respectively include male 40 people, female 20 people.
2, administration: take the health preserving wine that adopts the method for embodiment 3 to make by embodiment 1 medical material, take continuously after 6 days, feeling of fatigue disappears, the symptom of climacteric syndrome fades away, energy abundance, work spiritedness, immunity strengthen, take health preserving wine after stomach comfortable, without sense of discomfort.Experimental example 28: climacteric syndrome, companion's hypoimmunity
1, according to male 35-80 year, female 35-60 year, there is the symptom of climacteric syndrome, and the patient of hypoimmunity, respectively include male 40 people, female 20 people.
2, administration: take the health preserving wine of embodiment 4, take continuously after 6 days, feeling of fatigue disappears, the symptom of climacteric syndrome fades away, energy abundance, appetite increases, original BNO also unobstructed, the poor sleep of original sleep is also improved, work spiritedness, immunity strengthen, take health preserving wine after stomach comfortable, without sense of discomfort, stool is normal.
In sum and clinical experiment confirm, Chinese medicine composition (the five tastes of the present invention, Six-element) both had no side effect, there is again following health preservation treatment function: benefiting vital QI and blood, yin nourishing Yiyang, suppress thrombosis, improve immunity, resisting fatigue, prevent and treat climacteric syndrome, prevent and treat nine disease (deficiency of the kidney yin, insufficiency of kidney-YANG, kidney insufficiency, the hepatic and renal YIN deficiency, deficiency of spleen-YANG and kidneyYANG, deficiency of heart-yin, deficiency of heart-YANG, depression of liver-QI, disarmony between the heart and kidney) and a series of chronic diseases of causing, for example prostatic hyperplasia, lumbago and skelalgia, pessimistic, insomnia, weak, hypomnesis, QI and blood is two lose due to shallow complexion, dizzy cardiopalmus, energy deficiency, old and feeble very fast, the more symptoms of early whitening of beard and hair etc.
Although, above use general explanation, detailed description of the invention and test, the present invention is described in detail, on basis of the present invention, can make some modifications or improvements it, and this will be apparent to those skilled in the art.Therefore, these modifications or improvements without departing from theon the basis of the spirit of the present invention, all belong to the scope of protection of present invention.
Claims (20)
- A benefiting vital QI and blood, yin nourishing Yiyang, improve immunity, resisting fatigue, the thrombotic Chinese medicine composition of inhibition, it is characterized in that, described Chinese medicine composition is made up of the Chinese medicine of following weight portion: Radix Rehmanniae Preparata 10-30 part, Radix Angelicae Sinensis 5-15 part, Radix Codonopsis 10-30 part, Fructus Lycii 5-10 part and Radix Morindae Officinalis 3-10 part.
- 2. Chinese medicine composition according to claim 1, is characterized in that, described Chinese medicine composition is made up of the Chinese medicine of following weight portion: Radix Rehmanniae Preparata 15-25 part, Radix Angelicae Sinensis 5-10 part, Radix Codonopsis 15-25 part, Fructus Lycii 5-10 part and Radix Morindae Officinalis 7-10 part.
- 3. Chinese medicine composition according to claim 1, is characterized in that, described Chinese medicine composition is made up of the Chinese medicine of following weight portion: 10 parts of 20 parts of Radix Rehmanniae Preparata, 10 parts of Radix Angelicae Sinensis, 20 parts of Radix Codonopsis, 8 parts of Fructus Lycii and Radix Morindae Officinaliss.
- 4. a method of preparing Chinese medicine composition described in claim 1-3 any one, is characterized in that, the method comprises the following steps: take each Chinese medicine ingredients according to proportioning, then the 30-60 minute that Chinese medicine is soaked in water, amount of water be Chinese medicine gross weight 8-10 doubly, then boil, after boiling, the little fire state of boiling, decocts 2 hours, crosses leaching filtrate, add again Chinese medicine gross weight 6-8 water doubly, decoct 1-3 hour, filter, merge twice filtrate, concentrated, to obtain final product.
- 5. the preparation method of Chinese medicine composition according to claim 4, is characterized in that, comprises the following steps: take each Chinese medicine ingredients according to proportioning, then the 30-60 minute that Chinese medicine is soaked in water, amount of water be Chinese medicine gross weight 8-10 doubly, then boil, after boiling, the little fire state of boiling, decocts 2 hours, crosses leaching filtrate, add again Chinese medicine gross weight 6-8 water doubly, decoct 1.5-2 hour, filter, merge twice filtrate, be evaporated to dryly, obtain final product.
- 6. contain the health preserving wine of Chinese medicine composition described in claim 1-3 any one, it is characterized in that, employing following steps are made: take each Chinese medicine ingredients according to proportioning, then 30-60 minute is soaked in water Chinese medicine, amount of water is 6-10 times of Chinese medicine gross weight, then boil, the little fire state of boiling after boiling, decoct 1-3 hour, cross leaching filtrate, add again Chinese medicine gross weight 6-8 water doubly, decoct 1-3 hour, filter, merge filtrate twice, be concentrated into be equivalent to crude drug weight 1-2 doubly, obtain Chinese medicine composition decoction, then Chinese medicine composition decoction and white spirit mixing, the volume ratio of Chinese medicine composition decoction and this Chinese liquor is 1:(1-3), health preserving wine.
- 7. containing the preparation of Chinese medicine composition described in claim 1-3 any one, make separately or formed by this Chinese medicine composition and pharmaceutically acceptable carrier by this Chinese medicine composition.
- 8. preparation according to claim 7, is characterized in that, described preparation is decoction, tablet, capsule, pill or oral liquid.
- 9. the application of the preparation described in health preserving wine, claim 7 or 8 in the medicine of preparation treatment benefiting qi and nourishing blood, adjusting negative and positive described in Chinese medicine composition, claim 6 described in claim 1-3 any one.
- 10. application according to claim 9, it is characterized in that, described in be applied as adjusting immunity, resisting fatigue, prevent and treat climacteric syndrome, control deficiency of the kidney yin, insufficiency of kidney-YANG, kidney insufficiency, the hepatic and renal YIN deficiency, deficiency of spleen-YANG and kidneyYANG, deficiency of heart-yin, deficiency of heart-YANG, depression of liver-QI, disarmony between the heart and kidney, improve and strengthen function of five internal organs, prevents and treats thrombosis, resisting hypertension, blood fat reducing, blood sugar lowering, treatment lumbago and skelalgia, insomnia, forgetful or sexual hypofunction.
- 11. 1 kinds of benefiting vital QI and blood, yin nourishing Yiyang, improve immunity, resisting fatigue, the thrombotic Chinese medicine composition of inhibition, it is characterized in that, described Chinese medicine composition is made up of the Chinese medicine of following weight portion: Radix Rehmanniae Preparata 10-30 part, Radix Angelicae Sinensis 5-15 part, Radix Codonopsis 10-30 part, Fructus Lycii 5-10 part, Radix Morindae Officinalis 3-10 part and Radix Ophiopogonis 10-20 part.
- 12. Chinese medicine compositions according to claim 11, it is characterized in that, described Chinese medicine composition is made up of the Chinese medicine of following weight portion: Radix Rehmanniae Preparata 15-25 part, Radix Angelicae Sinensis 5-10 part, Radix Codonopsis 15-25 part, Fructus Lycii 5-10 part, Radix Morindae Officinalis 7-10 part and Radix Ophiopogonis 15-18 part.
- 13. Chinese medicine compositions according to claim 11, is characterized in that, described Chinese medicine composition is made up of the Chinese medicine of following weight portion: 15 parts of 20 parts of Radix Rehmanniae Preparata, 10 parts of Radix Angelicae Sinensis, 20 parts of Radix Codonopsis, 8 parts of Fructus Lycii, 10 parts of Radix Morindae Officinaliss and Radix Ophiopogonis.
- Prepare the method for Chinese medicine composition described in claim 11-13 any one for 14. 1 kinds, it is characterized in that, the method comprises the following steps: take each Chinese medicine ingredients according to proportioning, then the 30-60 minute that Chinese medicine is soaked in water, amount of water be Chinese medicine gross weight 8-10 doubly, then boil, after boiling, the little fire state of boiling, decocts 2 hours, crosses leaching filtrate, add again Chinese medicine gross weight 6-8 water doubly, decoct 1-3 hour, filter, merge twice filtrate, concentrated, to obtain final product.
- 15. according to the preparation method of Chinese medicine composition described in claim 14, it is characterized in that, comprises the following steps: take each Chinese medicine ingredients according to proportioning, then the 30-60 minute that Chinese medicine is soaked in water, amount of water be Chinese medicine gross weight 8-10 doubly, then boil, after boiling, the little fire state of boiling, decocts 2 hours, crosses leaching filtrate, add again Chinese medicine gross weight 6-8 water doubly, decoct 1.5-2 hour, filter, merge twice filtrate, be evaporated to dryly, obtain final product.
- 16. health preserving wines that contain Chinese medicine composition described in claim 11-13 any one, it is characterized in that, employing following steps are made: take each Chinese medicine ingredients according to proportioning, then 30-60 minute is soaked in water Chinese medicine, amount of water is 6-10 times of Chinese medicine gross weight, then boil, the little fire state of boiling after boiling, decoct 1-3 hour, cross leaching filtrate, add again Chinese medicine gross weight 6-8 water doubly, decoct 1-3 hour, filter, merge filtrate twice, be concentrated into be equivalent to crude drug weight 1-2 doubly, obtain Chinese medicine composition decoction, then Chinese medicine composition decoction and white spirit mixing, the volume ratio of Chinese medicine composition decoction and this Chinese liquor is 1:(1-3), health preserving wine.
- 17. preparations containing Chinese medicine composition described in claim 11-13 any one, are made separately or are made up of this Chinese medicine composition and pharmaceutically acceptable carrier by this Chinese medicine composition.
- 18. preparations according to claim 17, is characterized in that, described preparation is decoction, tablet, capsule, pill or oral liquid.
- The application of preparation described in health preserving wine, claim 17 or 18 in the medicine of preparation treatment benefiting qi and nourishing blood, adjusting negative and positive described in Chinese medicine composition, claim 16 described in 19. claim 11-13 any one.
- 20. application according to claim 19, it is characterized in that, described in be applied as adjusting immunity, resisting fatigue, prevent and treat climacteric syndrome, control deficiency of the kidney yin, insufficiency of kidney-YANG, kidney insufficiency, the hepatic and renal YIN deficiency, deficiency of spleen-YANG and kidneyYANG, deficiency of heart-yin, deficiency of heart-YANG, depression of liver-QI, disarmony between the heart and kidney, improve and strengthen function of five internal organs, prevents and treats thrombosis, resisting hypertension, blood fat reducing, blood sugar lowering, treatment lumbago and skelalgia, insomnia, forgetful or sexual hypofunction.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310284475.3A CN103316144B (en) | 2013-07-08 | 2013-07-08 | Chinese medicine composition capable of invigorating qi and blood, nourishing yin and yang, improving immunity, resisting to fatigue and inhibiting thrombogenesis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310284475.3A CN103316144B (en) | 2013-07-08 | 2013-07-08 | Chinese medicine composition capable of invigorating qi and blood, nourishing yin and yang, improving immunity, resisting to fatigue and inhibiting thrombogenesis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103316144A CN103316144A (en) | 2013-09-25 |
| CN103316144B true CN103316144B (en) | 2014-10-08 |
Family
ID=49185377
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310284475.3A Active CN103316144B (en) | 2013-07-08 | 2013-07-08 | Chinese medicine composition capable of invigorating qi and blood, nourishing yin and yang, improving immunity, resisting to fatigue and inhibiting thrombogenesis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103316144B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103695245A (en) * | 2013-12-24 | 2014-04-02 | 上海恪睿斯实业有限公司 | Compound wine and brewing method thereof |
| CN105901694A (en) * | 2016-04-13 | 2016-08-31 | 湖南楚明华医药有限公司 | Health food composition for enhancing immunity and production process thereof |
| CN105833148A (en) * | 2016-05-09 | 2016-08-10 | 宋述伋 | Traditional Chinese medicine composition with effects of improving memory, resisting arteriosclerosis, inhibiting thrombosis and improving immunity |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1226596A (en) * | 1997-12-18 | 1999-08-25 | 何解问 | Spirit containing Chinese herb angelica and wolfberry and preparation thereof |
| WO2008119131A1 (en) * | 2007-04-02 | 2008-10-09 | Medcina Group Pty Ltd | Herbal compositions and methods for treating female infertility |
| CN101993804A (en) * | 2009-08-25 | 2011-03-30 | 赵保云 | Preparation method of fleece-flower root and medlar wine |
| CN101914426A (en) * | 2010-07-17 | 2010-12-15 | 孙承宽 | Tortoise kidney tonifying wine |
| CN102614377A (en) * | 2012-04-23 | 2012-08-01 | 周良明 | Method for preparing life-prolonging health-care wine |
-
2013
- 2013-07-08 CN CN201310284475.3A patent/CN103316144B/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN103316144A (en) | 2013-09-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101322830B (en) | Medicament for treating postpartum depression and preparation method thereof | |
| CN102526474B (en) | Chinese medicine composition for treating neurasthenia | |
| CN102205107B (en) | Chinese medicinal preparation for treating duodenal ulcer and preparation method thereof | |
| CN104922475A (en) | Dendrobium candidum compound preparation for improving sub-health and preparing method thereof | |
| CN104958607A (en) | Traditional Chinese medicine composition for treating burning mouth syndromes of climacteric women and preparation method thereof | |
| CN102274453B (en) | Traditional Chinese medicine for treating diabetes and preparation method thereof | |
| CN103316144B (en) | Chinese medicine composition capable of invigorating qi and blood, nourishing yin and yang, improving immunity, resisting to fatigue and inhibiting thrombogenesis | |
| CN1109554C (en) | Medicine for treating allergic purpura | |
| CN102846955A (en) | Chinese herbal medicine heightening insole | |
| CN104274754A (en) | Traditional Chinese medicine composition for treating infantile enuresis and preparation method of traditional Chinese medicine composition | |
| CN103948782A (en) | Pharmaceutical composition for treating hyperplasia of mammary glands due to stagnation of liver qi as well as preparation method and application of pharmaceutical composition | |
| CN105999049A (en) | Traditional Chinese medicine composition for treating chronic renal failure and complications thereof | |
| CN104857454B (en) | A kind of traditional Chinese herbal decoction for treating Severe Acute Pancreatitis SAP | |
| CN104825800B (en) | A kind of medicine for the treatment of of insomnia patients and preparation method thereof | |
| CN102988747B (en) | Aristida triseta electuary for reducing hypertension, hyperglycemia and hyperlipidemia and preparation method thereof | |
| CN105535305A (en) | Chinese patent medicine for treating sequelae of cerebral infarction and preparation method thereof | |
| CN104940766A (en) | Dendrobium officinale traditional Chinese medicine composition for conditioning sub-health | |
| CN104758579A (en) | Traditional Chinese medicine for treating liver-kidney yin deficiency type climacteric syndrome | |
| CN104432386A (en) | Loranthus parasiticus oral liquid for preventing soreness and weakness of waist and knees and weak muscles and bones and preparation method thereof | |
| CN104721453B (en) | A kind of bellybutton-applying plaster of catharsis and toxin expelling and preparation method thereof, application method | |
| CN106822852A (en) | Treat pharmaceutical composition, its preparation technology and the purposes of coronary heart disease | |
| CN101406669B (en) | Chinese patent medicine for treating comedo and acne | |
| CN105944042A (en) | Traditional Chinese medicine for preventing coronary heart disease | |
| CN105012732A (en) | Traditional Chinese medicine pill for treating sleep disorder syndrome and preparation method thereof | |
| CN102579618B (en) | Yansheng pills |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |