CN105833060A - Compound lepidium meyenii product, and preparation method and application thereof - Google Patents

Compound lepidium meyenii product, and preparation method and application thereof Download PDF

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Publication number
CN105833060A
CN105833060A CN201510015902.7A CN201510015902A CN105833060A CN 105833060 A CN105833060 A CN 105833060A CN 201510015902 A CN201510015902 A CN 201510015902A CN 105833060 A CN105833060 A CN 105833060A
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China
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meyenii walp
lepidinm meyenii
parts
product
compound
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CN201510015902.7A
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Chinese (zh)
Inventor
程永现
郭世伟
程晓萍
吕青
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Yunnan Yihaomaka Biological Technology Development Co ltd
Kunming Institute of Botany of CAS
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Publication of CN105833060A publication Critical patent/CN105833060A/en
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Abstract

A compound lepidium meyenii product is prepared from the following raw materials, according to a weight ratio, 3-25 parts of lepidium meyenii, 3-20 parts of rhizoma polygonati, 3-20 parts of gordon euryale seeds, 3-20 parts of lophatherum herbs, and 0.5-5 parts of licorice roots. It is well known that lepidium meyenii is easy to cause excessive internal heat during administration. According to the fact, referring to the theory of traditional Chinese medicine, the invention provides a formula of the compound lepidium meyenii product having the functions of tonifying the kidney and supplementing essence and free of excessive internal heat, and a preparation method and an application of the compound lepidium meyenii product. The research shows that the prepared product can effectively overcome deficiency fire floating upward caused by administration of lepidium meyenii, thereby increasing the compliance of lepidium meyenii during usage. The method is beneficial for the sound development of lepidium meyenii industry.

Description

A kind of Lepidinm meyenii Walp compound product and preparation method and application
Technical field:
The invention belongs to drug technique or food (including health food) field, more particularly to a kind of Lepidinm meyenii Walp compound product Formula and preparation method thereof and application in sub-health population.
Background technology:
The effects such as Lepidinm meyenii Walp (Lepidium meyenii) has the kidney invigorating, calms the nerves, resisting fatigue, thus cause global concern.2012 Year, Lepidinm meyenii Walp started its sale heat in China especially after being approved as new resource food by China's Ministry of Public Health, and current Lepidinm meyenii Walp is in China Awareness degree the highest.But substantial amounts of crowd generally reflects discomforts such as getting angry during using Lepidinm meyenii Walp, thus even terminates it Continue to take, the most therefore lost the important health care of Lepidinm meyenii Walp.Therefore solve Lepidinm meyenii Walp get angry become Lepidinm meyenii Walp research in one Individual key problem, but have not yet to see the effective way solving this problem.
Summary of the invention:
It is an object of the invention to provide a kind of high rhythm society overdraw crowd adjust benefit containing Lepidinm meyenii Walp traditional Chinese compound medicine or health Food;Lie also in by the compounding problem of getting angry evaded and occurring during Lepidinm meyenii Walp uses.
The above-mentioned purpose of the present invention is to be achieved by following technical scheme:
The preparation that described a kind of Lepidinm meyenii Walp compound product is made up of the raw material of following weight proportioning:
Lepidinm meyenii Walp 3~25 parts, Rhizoma Polygonati 3~20 parts, Semen Euryales 3~20 parts, Herba Lophatheri 3~20 parts, Radix Glycyrrhizae 0.5~5 parts;Described Lepidinm meyenii Walp is Refer to Cruciferae separate row Vegetable spp plant Maca (Lepidium meyenii Walp);Lepidinm meyenii Walp can be health product or according to routine side The parched medicinal material that method is made, it is also possible to be the processed product made according to conventional concocting method as adjuvant according to Semen sojae atricolor and Sal; Rhizoma Polygonati, Radix Glycyrrhizae can be health product or the processed product conventionally prepared.
Described a kind of Lepidinm meyenii Walp compound product, the weight proportion of the most each raw material is: Lepidinm meyenii Walp 22.5 parts, Rhizoma Polygonati 9 parts, Gorgon euryale Real 9 parts, Herba Lophatheri 7.5 parts, 2.25 parts of Radix Glycyrrhizae.
Described a kind of Lepidinm meyenii Walp compound product, it can be oral administration solid or liquid preparation.
Described a kind of Lepidinm meyenii Walp compound product, it can be medicated wine or tablet.
Present invention also offers the preparation method of a kind of Lepidinm meyenii Walp compound product: take raw material in prescription, decoction pieces feeds intake, and uses water (30%~80%, ml/g) soaks and runs through, and water is that solvent decocts 1~3 time, each 6~12 times amount, each 1~3 hour, United extraction liquid, filters, and it is 1.10~1.3 that less than 60 DEG C concentrating under reduced pressure adjust at 60~90 DEG C relative density, and concentrated solution enters Row is dried, the direct package encapsulation of dried powder and get final product.
The preparation method of described a kind of Lepidinm meyenii Walp compound product is to take all raw materials in prescription, be ground into soybean grain size, Edible ethanol with 40%~95% is soaked 6~12 hours, starts percolation, and flow velocity is 3~6ml/min/kg, collects percolate 4~16 times of volumes, less than 60 DEG C concentrating under reduced pressure, concentrated solution is dried, direct package encapsulation and get final product.
Described Lepidinm meyenii Walp processed product is, Lepidinm meyenii Walp is taken advantage of fresh-cut and become 2-8mm sheet, dries, with 0.2-0.8 times of water soaking 1-2 Hour to interior without the dry heart, then fry 20-50 minute with 60-120 DEG C, during without acid, pack after drying, or agate Coffee is taken advantage of fresh-cut and is become 2-8mm sheet, dries, and takes the dry Semen sojae atricolor of 5-10% Lepidinm meyenii Walp amount, with the soak by water Semen sojae atricolor 1-3 of 4-8 times Secondary, decoct 30 minutes-1 hour, suitable condensed water decoction liquor every time, make salinity in water be Semen sojae atricolor weight with Sal 10%, it is used for soaking Lepidinm meyenii Walp 40 minutes-2 hours, to interior without the dry heart, then fries 20-50 minute, to nothing with 60-120 DEG C During acid, pack after drying, or Lepidinm meyenii Walp is taken advantage of fresh-cut and become 2-8mm sheet, dries, by Lepidinm meyenii Walp weight 30-50% Water soaking Lepidinm meyenii Walp 40 minutes-2 hours, to interior without the dry heart, then at 60-90 DEG C, normal pressure steams 5-20 minute, to without pungent During pungent, pack after drying.
Described arbitrary Lepidinm meyenii Walp formula is not got angry preparing kidney tonifying, essence replenishing, resisting fatigue, improves sleep and kidney invigorating and YANG supporting is obvious Application in product.
Detailed description of the invention:
Further illustrate the essentiality content of the present invention below with embodiments of the invention, but do not limit this with this Bright.The simple modifications that the present invention is carried out by the essence according to the present invention broadly falls into the scope of protection of present invention.
Embodiment 1:
A kind of Lepidinm meyenii Walp compound product, the weight proportion of the most each raw material is: Lepidinm meyenii Walp 22.5 parts, Rhizoma Polygonati 9 parts, Semen Euryales 9 parts, Herba Lophatheri 7.5 parts, 2.25 parts of Radix Glycyrrhizae.
Its compound method is: take raw material in prescription, and decoction pieces feeds intake, and soaks with water (50%, ml/g) and runs through, and water is solvent Decocting 2 times, each 8 times amount, each 1 hour, united extraction liquid, filter, less than 60 DEG C concentrating under reduced pressure adjust to 60~90 At DEG C, relative density is 1.25, and concentrated solution is dried, the direct package encapsulation of dried powder and get final product.
Embodiment 2:
A kind of Lepidinm meyenii Walp compound product, the weight proportion of the most each raw material is: Lepidinm meyenii Walp 22.5 parts, Rhizoma Polygonati (processed) 9 parts, Semen Euryales 9 Part, Herba Lophatheri 7.5 parts, 2.25 parts of Radix Glycyrrhizae.
Its compound method is: take raw material in prescription, and decoction pieces feeds intake, and soaks with water (50%, ml/g) and runs through, and water is solvent Decoct 2 times, each 6 times amount, each 1.5 hours, united extraction liquid, filter, less than 60 DEG C concentrating under reduced pressure adjust to At 60~90 DEG C, relative density is 1.25, and concentrated solution is dried, the direct package encapsulation of dried powder and get final product.
Embodiment 3:
A kind of Lepidinm meyenii Walp compound product, the weight proportion of the most each raw material is: Lepidinm meyenii Walp 22.5 parts, Rhizoma Polygonati (processed) 9 parts, Semen Euryales 9 Part, Herba Lophatheri 7.5 parts, 2.25 parts of Radix Glycyrrhizae.
Its compound method is: takes all raw materials in prescription, is ground into soybean grain size, and the edible ethanol with 55% soaks 12 Hour, starting percolation, flow velocity is 5ml/min/kg, collects 8 times of volumes of percolate, less than 60 DEG C concentrating under reduced pressure, concentrates Liquid is dried, direct package encapsulation and get final product.
Embodiment 4:
A kind of Lepidinm meyenii Walp compound product, the weight proportion of the most each raw material is: Lepidinm meyenii Walp 22.5 parts, Rhizoma Polygonati (processed) 9 parts, Semen Euryales 9 Part, Herba Lophatheri 7.5 parts, 2.25 parts of Radix Glycyrrhizae.
Its compound method is: takes all raw materials in prescription, is ground into soybean grain size, and the edible ethanol with 80% soaks 12 Hour, starting percolation, flow velocity is 6ml/min/kg, collection 15 times of volumes of percolate, and less than 60 DEG C concentrating under reduced pressure are dense Contracting liquid is dried, direct package encapsulation and get final product.
Embodiment 5:
A kind of Lepidinm meyenii Walp compound product, the weight proportion of the most each raw material is: Lepidinm meyenii Walp 22.5 parts, Rhizoma Polygonati (processed) 9 parts, Semen Euryales 9 Part, Herba Lophatheri 7.5 parts, 2.25 parts of Radix Glycyrrhizae.
It is prepared into dry extract according to embodiment 3 preparation method, under stirring condition, extract is dissolved, filter, preparation Become wine, every bottle of 500ml.
Embodiment 6:
A kind of Lepidinm meyenii Walp compound product, the weight proportion of the most each raw material is: Lepidinm meyenii Walp 450g, Rhizoma Polygonati (processed) 180g, Semen Euryales 180 G, Herba Lophatheri 150g, Radix Glycyrrhizae 45g.
It is prepared into dry extract according to embodiment 3 preparation method, under stirring condition, extract is dissolved, filter, preparation Become 20 bottles of wine, every bottle of 500ml.
Embodiment 7:
A kind of Lepidinm meyenii Walp compound product, the weight proportion of the most each raw material is: Lepidinm meyenii Walp 225g, Rhizoma Polygonati (processed) 90g, Semen Euryales 90g, Herba Lophatheri 75g, Radix Glycyrrhizae 22.5g.
It is prepared into dry extract according to embodiment 3 preparation method, adds starch, dextrin, conventionally make different Matrix, every tablet weight 0.5g.
Embodiment 8:
The assembled alcoholic drinks that embodiment 6 prepares, finds 10 and once drank the businessman that independent Lepidinm meyenii Walp steeps in wine and carry out comparative study, often People drinks 200ml every day, and wherein 1 people drops by the wayside, and remaining 9 people adheres to drinking 5 days, is discovery and significantly gets angry Phenomenon, relatively equivalent Lepidinm meyenii Walp effect of steeping in wine is obvious, and wherein 1 people suffers from oral ulcer, healing the most naturally during drinking.
Embodiment 9:
The wine that embodiment 1 technique is made, drinks through 15 example experimenters, and function for tonifying kidney is compared with the wine obtained by embodiment 6 technique Agent has declined, but does not all reflect there is phenomenon of getting angry.
Embodiment 10:
The tablet that embodiment 7 is made, takes according to adult every day 4, has 10 people and participates in, during taking 20 days, All do not occur phenomenon of getting angry per capita, feels energetic, does not the most feel sleepy even without lunch break.
Embodiment 11:
Lepidinm meyenii Walp 15g, Rhizoma Polygonati 5g, Semen Euryales 3g, Herba Lophatheri 4g, Radix Glycyrrhizae 1g.Above-mentioned raw materials amount, according to embodiment 3 technique Make 1 bottle of 500ml wine, altogether system 10 bottles.Through subject feedback, the effect similar with embodiment 8 can be received, do not find Get angry, but function for tonifying kidney onset time is slower than embodiment 8.
" get angry " and as will be readily understood that, but it is the most effective to " getting angry " to observe the present invention, be but difficult to come with animal model Carry out.The raw materials used product being medicine-food two-purpose in inventive formulation, safety is high, in consideration of it, take in research process The voluntary trial method of a large amount of crowds of similar clinical research.In order to make product have intension and strong vitality, no matter from mouth Sense, effect and pathogenic fire reducing aspect have all carried out experience screening repeatedly and laboratory observation, have ultimately formed the elite of the present invention.Logical Cross solution to get angry problem so that the compliance taking Lepidinm meyenii Walp formulation product increases, it is contemplated that will overdraw crowd to high rhythm society Health play active protection effect.

Claims (8)

1. a Lepidinm meyenii Walp compound product, it is characterised in that the preparation that it is made up of the raw material of following weight proportioning:
Lepidinm meyenii Walp 3~25 parts, Rhizoma Polygonati 3~20 parts, Semen Euryales 3~20 parts, Herba Lophatheri 3~20 parts, Radix Glycyrrhizae 0.5~5 parts;Described Lepidinm meyenii Walp refers to Cruciferae separate row Vegetable spp plant Maca (Lepidium meyenii Walp), and Lepidinm meyenii Walp is health product or the parched medicinal material made according to a conventional method, or the processed product made as adjuvant concocting method routinely by Semen sojae atricolor and Sal;Described Rhizoma Polygonati, Radix Glycyrrhizae are health product or the processed product prepared according to a conventional method.
2. a kind of Lepidinm meyenii Walp compound product as claimed in claim 1, the weight proportion of the most each raw material is: Lepidinm meyenii Walp 22.5 parts, Rhizoma Polygonati 9 parts, Semen Euryales 9 parts, Herba Lophatheri 7.5 parts, 2.25 parts of Radix Glycyrrhizae.
3. a kind of Lepidinm meyenii Walp compound product as claimed in claim 1 or 2, it is characterized in that described Lepidinm meyenii Walp processed product is, Lepidinm meyenii Walp is taken advantage of fresh-cut and is become 2 8mm sheets, dry, with 0.2 0.8 times of water soakings 12 hours to interior without the dry heart, then fry 20 50 minutes with 60 120 DEG C, during without acid, pack after drying;Or Lepidinm meyenii Walp takes advantage of fresh-cut and becomes 2 8mm sheets, dry, take the dry Semen sojae atricolor of 5 10% Lepidinm meyenii Walp amounts, with the soak by water Semen sojae atricolor 13 times of 48 times, decoct 30 minutes 1 hour every time, suitably condensed water decoction liquor, makes salinity in water be the 10% of Semen sojae atricolor weight with Sal, is used for soaking Lepidinm meyenii Walp 40 minutes 2 hours, to interior without the dry heart, then fry 20 50 minutes with 60 120 DEG C, to during without acid, pack after drying;Or Lepidinm meyenii Walp takes advantage of fresh-cut and become 2 8mm sheets, drying, with the water soaking Lepidinm meyenii Walp 40 minutes 2 hours of Lepidinm meyenii Walp weight 30 50%, to interior without the dry heart, then at 60 90 DEG C, normal pressure steams 5 20 minutes, to during without acid, packs after drying.
4. a kind of Lepidinm meyenii Walp compound product as claimed in claim 1 or 2, it is characterised in that described preparation is oral administration solid or liquid preparation.
5. a kind of Lepidinm meyenii Walp compound product as claimed in claim 4, it is characterised in that this described preparation is medicated wine or tablet.
6. the preparation method of a kind of Lepidinm meyenii Walp compound product described in claim 2, it is characterised in that: taking raw material in compound recipe, decoction pieces feeds intake, with water 30%~80%, ml/g soaks and runs through, and water is that solvent decocts 1~3 time, each 6~12 times amount, each 1~3 hour, united extraction liquid, filters, and it is 1.10~1.3 that less than 60 DEG C concentrating under reduced pressure adjust at 60~90 DEG C relative density, concentrated solution is dried, the direct package encapsulation of dried powder.
7. the preparation method of a kind of Lepidinm meyenii Walp compound product described in claim 2, it is characterized in that: take all raw materials in compound recipe, it is ground into soybean grain size, edible ethanol with 40%~95% is soaked 6~12 hours, starts percolation, and flow velocity is 3~6ml/min/kg, collect percolate 4~16 times of volumes, less than 60 DEG C concentrating under reduced pressure, concentrated solution is dried, direct package encapsulation.
8. the Lepidinm meyenii Walp compound product described in claim 1 or 2 or 3 is not got angry preparing kidney tonifying, essence replenishing, resisting fatigue, improves sleep and kidney invigorating and YANG supporting significantly containing the application in Lepidinm meyenii Walp product.
CN201510015902.7A 2015-01-13 2015-01-13 Compound lepidium meyenii product, and preparation method and application thereof Pending CN105833060A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110384769A (en) * 2018-04-12 2019-10-29 温州市金权食品股份有限公司 A kind of pizzle renal drug and preparation method thereof with Yang-establishing health

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110384769A (en) * 2018-04-12 2019-10-29 温州市金权食品股份有限公司 A kind of pizzle renal drug and preparation method thereof with Yang-establishing health

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Effective date of registration: 20191031

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Application publication date: 20160810