CN105832733A - 高剂量拉喹莫德(laquinimod)用于治疗多发性硬化症的用途 - Google Patents
高剂量拉喹莫德(laquinimod)用于治疗多发性硬化症的用途 Download PDFInfo
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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| CN201380022530.XA CN104284663A (zh) | 2012-05-02 | 2013-05-01 | 高剂量拉喹莫德(laquinimod)用于治疗多发性硬化症的用途 |
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| CN201610240473.8A Pending CN105832733A (zh) | 2012-05-02 | 2013-05-01 | 高剂量拉喹莫德(laquinimod)用于治疗多发性硬化症的用途 |
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| BR (1) | BR112014027010A2 (enExample) |
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| ZA (1) | ZA201408820B (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8889627B2 (en) | 2011-10-12 | 2014-11-18 | Teva Pharmaceutical Industries, Ltd. | Treatment of multiple sclerosis with combination of laquinimod and fingolimod |
| CN106063787A (zh) | 2012-02-03 | 2016-11-02 | 泰华制药工业有限公司 | 拉喹莫德用于治疗一线抗TNFα疗法失败的克罗恩氏病患者的用途 |
| AU2013221304B2 (en) | 2012-02-16 | 2017-12-21 | Teva Pharmaceutical Industries Ltd. | N-ethyl-N-phenyl-1,2-dihydro-4,5-di-hydroxy-1-methyl-2-oxo-3-quinoline carboxamide, preparation and uses thereof |
| US20130259856A1 (en) * | 2012-03-27 | 2013-10-03 | Teva Pharmaceutical Industries, Ltd. | Treatment of multiple sclerosis with combination of laquinimod and dimethyl fumarate |
| TW201400117A (zh) | 2012-06-05 | 2014-01-01 | Teva Pharma | 使用拉喹莫德治療眼發炎疾病 |
| TW201410244A (zh) | 2012-08-13 | 2014-03-16 | Teva Pharma | 用於治療ｇａｂａ媒介之疾病之拉喹莫德（ｌａｑｕｉｎｉｍｏｄ） |
| HK1218865A1 (zh) * | 2012-10-12 | 2017-03-17 | Teva Pharmaceutical Industries Ltd. | 用於降低多发性硬化症中丘脑损伤的拉喹莫德 |
| EA201590788A1 (ru) | 2012-11-07 | 2015-12-30 | Тева Фармасьютикал Индастриз Лтд. | Аминные соли лахинимода |
| CA2900503A1 (en) * | 2013-02-15 | 2014-08-21 | Teva Pharmaceutical Industries Ltd. | Treatment of multiple sclerosis with laquinimod |
| AU2014236232A1 (en) | 2013-03-14 | 2015-11-05 | Teva Pharmaceutical Industries Ltd. | Crystals of laquinimod sodium and improved process for the manufacture thereof |
| AR098924A1 (es) * | 2013-12-23 | 2016-06-22 | Teva Pharma | Tratamiento de la esclerosis múltiple con una combinación de laquinimod y teriflunomida |
| JP2017514824A (ja) * | 2014-04-29 | 2017-06-08 | テバ ファーマシューティカル インダストリーズ リミティド | 能力障害度が高い再発寛解型多発性硬化症（ｒｒｍｓ）患者の処置のためのラキニモド |
| WO2017027512A1 (en) * | 2015-08-13 | 2017-02-16 | Teva Pharmaceutical Industries Ltd. | Use of laquinimod to treat traumatic brain injury |
| US20190108912A1 (en) * | 2017-10-05 | 2019-04-11 | Iquity, Inc. | Methods for predicting or detecting disease |
| FI3823623T3 (fi) * | 2018-07-20 | 2025-01-09 | Merck Patent Gmbh | Substituoitu aminopyrimidiiniyhdiste käytettäväksi pesäkekovettumataudin hoito- ja ehkäisymenetelmässä |
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| WO2011086470A1 (en) * | 2010-01-13 | 2011-07-21 | Ramot At Tel-Aviv University Ltd | Treatment of multiple sclerosis |
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| US6077851A (en) * | 1998-04-27 | 2000-06-20 | Active Biotech Ab | Quinoline derivatives |
| DK1797109T3 (en) * | 2004-09-09 | 2016-04-11 | Yeda Res & Dev | MIXTURES OF POLYPEPTIDES, compositions containing them and methods for their preparation, and uses thereof |
| US20080118553A1 (en) * | 2006-06-12 | 2008-05-22 | Anton Frenkel | Tannate salt form of polypeptide mixtures, their preparation and use |
| US20100322900A1 (en) * | 2009-06-19 | 2010-12-23 | Teva Pharmaceutical Industries, Ltd. | Treatment of multiple sclerosis with laquinimod |
| US8889627B2 (en) * | 2011-10-12 | 2014-11-18 | Teva Pharmaceutical Industries, Ltd. | Treatment of multiple sclerosis with combination of laquinimod and fingolimod |
| CA2900503A1 (en) * | 2013-02-15 | 2014-08-21 | Teva Pharmaceutical Industries Ltd. | Treatment of multiple sclerosis with laquinimod |
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2013
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- 2013-05-01 CA CA2870684A patent/CA2870684A1/en not_active Abandoned
- 2013-05-01 EA EA201492010A patent/EA201492010A1/ru unknown
- 2013-05-01 PE PE2014001911A patent/PE20150161A1/es not_active Application Discontinuation
- 2013-05-01 EP EP13784231.6A patent/EP2844255A4/en not_active Withdrawn
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- 2013-05-01 JP JP2015510436A patent/JP2015515985A/ja not_active Withdrawn
- 2013-05-01 US US13/874,537 patent/US20130303569A1/en not_active Abandoned
- 2013-05-01 CN CN201380022530.XA patent/CN104284663A/zh active Pending
- 2013-05-01 CN CN201610240473.8A patent/CN105832733A/zh active Pending
- 2013-05-01 WO PCT/US2013/039090 patent/WO2013166166A1/en not_active Ceased
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2014
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2015
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2017
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011086470A1 (en) * | 2010-01-13 | 2011-07-21 | Ramot At Tel-Aviv University Ltd | Treatment of multiple sclerosis |
Non-Patent Citations (4)
| Title |
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| C.POLMAN等: "Treatment with laquinimod reduces development of active MRI lesions in relapsing MS", 《NEUROLOGY》 * |
| JANA PREININGEROVA: "Oral laquinimod therapy in relapsing multiple sclerosis", 《EXPERT OPIN.INVESTIG.DRUGS》 * |
| SUSAN JEFFREY: "Laquinimod Slows Progression in MS:ALLEGRO Published", 《MEDSCAPE MEDICAL NEWS》 * |
| 余永平等: "《现代实用神经病学》", 30 September 2011, 天津科学技术出版社 * |
Also Published As
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| CL2014002935A1 (es) | 2015-03-06 |
| KR20150013658A (ko) | 2015-02-05 |
| US20160000775A1 (en) | 2016-01-07 |
| US20130303569A1 (en) | 2013-11-14 |
| EA201492010A1 (ru) | 2015-06-30 |
| MX2014013039A (es) | 2015-02-04 |
| TW201347762A (zh) | 2013-12-01 |
| CA2870684A1 (en) | 2013-11-07 |
| AU2013256352A1 (en) | 2014-11-27 |
| HK1206246A1 (en) | 2016-01-08 |
| UY34775A (es) | 2013-11-29 |
| PE20150161A1 (es) | 2015-02-22 |
| EP2844255A1 (en) | 2015-03-11 |
| JP2015515985A (ja) | 2015-06-04 |
| IL235337A0 (en) | 2014-12-31 |
| WO2013166166A1 (en) | 2013-11-07 |
| BR112014027010A2 (pt) | 2017-06-27 |
| CN104284663A (zh) | 2015-01-14 |
| ZA201408820B (en) | 2016-06-29 |
| AR090885A1 (es) | 2014-12-10 |
| PH12014502447A1 (en) | 2015-01-12 |
| US20150265592A1 (en) | 2015-09-24 |
| JP2017222691A (ja) | 2017-12-21 |
| SG11201406594UA (en) | 2014-11-27 |
| EP2844255A4 (en) | 2015-10-14 |
| TW201804997A (zh) | 2018-02-16 |
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