CN105829286B - 作为lta4h抑制剂的杂芳基丁酸衍生物 - Google Patents

作为lta4h抑制剂的杂芳基丁酸衍生物 Download PDF

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CN105829286B
CN105829286B CN201480069263.6A CN201480069263A CN105829286B CN 105829286 B CN105829286 B CN 105829286B CN 201480069263 A CN201480069263 A CN 201480069263A CN 105829286 B CN105829286 B CN 105829286B
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compound
base
phenyl
amino
tetrazolium
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CN105829286A (zh
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B·博尔巴克
C·马克尔特
W·米尔茨
T·罗恩
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Novartis AG
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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CN201480069263.6A 2013-12-20 2014-12-18 作为lta4h抑制剂的杂芳基丁酸衍生物 Active CN105829286B (zh)

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Application Number Priority Date Filing Date Title
EP13199138.2 2013-12-20
EP13199138 2013-12-20
EP14181155.4 2014-08-15
EP14181155 2014-08-15
PCT/IB2014/067086 WO2015092740A1 (en) 2013-12-20 2014-12-18 Heteroaryl butanoic acid derivatives as lta4h inhibitors

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CN105829286A CN105829286A (zh) 2016-08-03
CN105829286B true CN105829286B (zh) 2019-05-31

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Publication number Priority date Publication date Assignee Title
WO2017175185A1 (en) 2016-04-08 2017-10-12 Novartis Ag Heteroaryl butanoic acid derivatives as lta4h inhibitors
CN112469439A (zh) 2018-05-15 2021-03-09 万能溶剂有限公司 用白三烯a4水解酶调节剂治疗衰老相关性疾病
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