CN1058153C - Compound metronidazole suppository - Google Patents
Compound metronidazole suppository Download PDFInfo
- Publication number
- CN1058153C CN1058153C CN 97100656 CN97100656A CN1058153C CN 1058153 C CN1058153 C CN 1058153C CN 97100656 CN97100656 CN 97100656 CN 97100656 A CN97100656 A CN 97100656A CN 1058153 C CN1058153 C CN 1058153C
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- CN
- China
- Prior art keywords
- suppository
- metronidazole
- compound
- vaginitis
- compound metronidazole
- Prior art date
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- Expired - Fee Related
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Abstract
The present invention relates to a new medicament for treating gynecological diseases, comprising senile vaginitis and trichomonal vaginitis, namely a compound metronidazole suppository. Polyethylene glycol 4000, polyethylene glycol 400, distilled water and Tween-80 are taken and put in a water bath, heated, and melted, and metronidazole and the saponin powder of ginseng stem leaves are added during continuous stirring; vitamin E is added, and the solution is uniformly stirred to be prepared into the suppository. The compound metronidazole suppository can treat gynecological diseases, comprising internal vaginitis, epivaginitis, trichomonal vaginitis, and the like., and the compound metronidazole suppository has the advantages of convenient treatment, fast effect, high cure rate and short period. The compound metronidazole suppository can thoroughly and cleanly eliminate trouble caused by pruritus, swelling pain and gonorrhea which are caused by gynecological diseases.
Description
The present invention relates to a kind of new drug-compound metronidazole suppository for the treatment of senile vaginitis, trichomonal vaginitis gynaecopathia.
Gynaecopathia, especially inside and outside cloudy disease is usually brought the hardship of feeling embarrassed to mention to the womankind, there are a lot of women to get gynaecopathia as vulvitis, trichomonal vaginitis, non-characteristic vaginitis, senile vaginitis, cervical erosion etc., these serious illness are brought scratch where it itches, swell and ache at every moment troubling them, so in the society all instant hope develop faster a kind of can the above-mentioned gynaecopathia of treatment, and the short specific drug of instant effect, cure rate height, healing cycle.
The object of the present invention is to provide and a kind ofly can treat gynaecopathia, particularly can treat the new drug of gynaecopathias such as inside and outside vaginitis, trichomonal vaginitis, and instant effect, cure rate height, short compound metronidazole suppository of healing cycle.
The object of the present invention is achieved like this taking polyethylene glycol, distilled water, tween are put in the water-bath heating and are dissolved, under constantly stirring, add metronidazole and stem and leaf of Radix Ginseng saponin powder, add vitamin E then, stir and make suppository, it is characterized in that its raw materials in part by weight is:
Metronidazole 400-600g
Stem and leaf of Radix Ginseng saponin 20-30g
Vitamin E 35-45g
Tween .80 35-45g
Macrogol 4000 2000-2100g
PEG400 950-1100g
Water 280-380g.
Compound metronidazole suppository of the present invention, its feature are that also its raw materials in part by weight is preferably:
Metronidazole 500.0g
Stem and leaf of Radix Ginseng saponin 25.0g
Vitamin E 40.0g
Tween .80 40.0g
Macrogol 4000 2037.0g
PEG400 1018.5g
Water 339.5g.
Compound metronidazole suppository new drug of the present invention, can treat gynaecopathias such as inside and outside vaginitis, trichomonal vaginitis, it treats convenient, and instant effect, cure rate height, cycle are short, and elimination that can be thorough, clean was because gynaecopathia brought scratches where it itches, swell and ache, troubling with pouring.
Below in conjunction with embodiment the present invention is described, the scheme of embodiment described here, do not limit the present invention, one of skill in the art can make improvements and change according to spirit of the present invention, described these improvement and variation all should be considered as within the scope of the invention, and scope and spirit of the present invention are limited by claim.
Embodiment
Get: metronidazole 500.0g
Stem and leaf of Radix Ginseng saponin 25.0g
Vitamin E 40.0g
Tween .80 40.0g
Macrogol 4000 2037.0g
PEG400 1018.5g
Water 339.5g.
And with Macrogol 4000, PEG400, distilled water, tween.80 put in the water-bath heating dissolves, and adds metronidazole and stem and leaf of Radix Ginseng saponin powder under constantly stirring, and adds vitamin E then, stirs and makes 1000 off-white colors or yellowish vaginal suppository, promptly gets product of the present invention.
Claims (3)
1, a kind of compound metronidazole suppository is characterized in that raw materials in part by weight is:
Metronidazole 400-600g
Stem and leaf of Radix Ginseng saponin 20-30g
Vitamin E 35-45g
Tween 80 35-45g
Macrogol 4000 2000-2100g
PEG400 950-1100g
Water 280-380g
2, according to the compound metronidazole suppository of claim 1, its feature is that also its raw materials in part by weight is preferably:
Metronidazole 500.0g
Stem and leaf of Radix Ginseng saponin 25.0g
Vitamin E 40.0g
Tween 80 40.0g
Macrogol 4000 1018.0g
PEG400 1018.5g
Water 339.5g
3, according to the preparation method of the compound metronidazole suppository of claim 1 or 2, this method is that taking polyethylene glycol 4000, PEG400, distilled water, tween 80 are put heat fused in the water-bath, under constantly stirring, add metronidazole and stem and leaf of Radix Ginseng saponin powder, add vitamin E then, the suppository that stirs and make.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 97100656 CN1058153C (en) | 1997-03-07 | 1997-03-07 | Compound metronidazole suppository |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 97100656 CN1058153C (en) | 1997-03-07 | 1997-03-07 | Compound metronidazole suppository |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1240650A CN1240650A (en) | 2000-01-12 |
| CN1058153C true CN1058153C (en) | 2000-11-08 |
Family
ID=5165218
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 97100656 Expired - Fee Related CN1058153C (en) | 1997-03-07 | 1997-03-07 | Compound metronidazole suppository |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1058153C (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103285055A (en) * | 2013-05-17 | 2013-09-11 | 哈尔滨欧替药业有限公司 | Compound metronidazole expansion suppository, preparation technology and detection method thereof |
-
1997
- 1997-03-07 CN CN 97100656 patent/CN1058153C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1240650A (en) | 2000-01-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C06 | Publication | ||
| PB01 | Publication | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| DD01 | Delivery of document by public notice |
Addressee: Li Fangrui Document name: Notification to Pay the Fees |
|
| DD01 | Delivery of document by public notice |
Addressee: Li Fangrui Document name: Notification of Termination of Patent Right |
|
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20001108 Termination date: 20160307 |