CN105770571A - Medicament for treating epilepsy - Google Patents
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K36/74—Rubiaceae (Madder family)
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- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
- A61K36/8884—Arisaema, e.g. Jack in the pulpit
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Abstract
The invention discloses a medicament for treating epilepsy. The medicament is prepared from the following raw materials in parts by weight: 12 to 18 parts of tangerine peel, 12 to 18 parts of rhizoma Pinellinae Praeparata, 10 to 15 parts of arisaema cum bile, 10 to 15 parts of poria, 8 to 12 parts of rhizoma acori graminei, 8 to 12 parts of radix polygalae, 5 to 7 parts of ossa draconis, 5 to 7 parts of rhizoma atractylodis macrocephalae, 12 to 18 parts of uncaria rhynchophylla, 5 to 8 parts of radix glycyrrhizae, 8 to 10 parts of caulis bambusae in taeniam, 10 to 15 parts of bombyx batryticatus and 10 to 15 parts of radix codonopsis. According to the medicament for treating epilepsy, disclosed by the invention, 13 kinds of natural traditional Chinese medicines are selected for scientifically matching; and a formula is simple; all active pharmaceutical ingredients are synergized to realize the effects of clearing away the heart-fire and relieving convulsion, clearing away heat and toxic materials, and soothing nerves and aiding sleeping; the medicament has quick effects, treatment of both manifestation and root cause of disease and no toxic and side effect; in addition, the medicament is simple in preparation method, convenient in administration and low in cost; the effective rate reaches 93 percent or over 93 percent.
Description
Technical field
The present invention relates to Chinese medicine, a kind of medicine treating epilepsy.
Background technology
" epilepsy " or " epilepsy " that epilepsy is i.e. commonly called as, is owing to cerebral neuron paroxysmal abnormality discharges, and causes a kind of chronic disease of of short duration cerebral disorder.Due to initial position and the difference of transfer mode of paradoxical discharge, the complicated clinical manifestation of epilepsy is various, can behave as paroxysmal movement, sensation, autonomic nerve, consciousness and mental disorder.The cause of disease causing epilepsy is varied.Epileptic can be controlled through regular Antiepileptic Drugs, its outbreak of the patient of about 70%, and wherein the patient of 50%~60% can fully recover through the treatment of 2-5, and patient can equally work with normal person and live.
Epilepsy is found in all age group.Epilepsy in childhood sickness rate is relatively grown up height, and with advancing age, epilepsy invasion rate decreases.Entrance geratic period (after 65 years old) increases due to cerebrovascular, senile dementia and neurodegenerative diseases, and epilepsy invasion rate is shown in again rising.Due to initial position and the difference of transfer mode of paradoxical discharge, the complicated clinical manifestation of epilepsy is various.
Existing Therapeutic Method is many mainly based on Drug therapy, the also method such as etiological treatment, surgical intervention, and not only side effect is big, and can not cure completely, easily recurs, patient's economy and physiology are caused certain burden.And the therapeutic efficiency of some current Chinese medicines is the most not satisfactory, treatment cycle is long, and curative effect is the most notable.
Summary of the invention
It is an object of the invention to provide a kind of good effect, short treating period, low cost, the medicine for the treatment of epilepsy that has no side effect.
The technical scheme realizing the object of the invention is:
A kind of medicine treating epilepsy, is made up of the raw material of following weight parts proportioning:
Pericarpium Citri Reticulatae 12-18 part, Rhizoma Pinelliae Preparatum 12-18 part, Arisaema Cum Bile 10-15 part, Poria 10-15 part, Rhizoma Acori Graminei 8-12 part, Radix Polygalae 8-12 part, Os Draconis 5-7 part, Rhizoma Atractylodis Macrocephalae 5-7 part, Ramulus Uncariae Cum Uncis 12-18 part, Radix Glycyrrhizae 5-8 part, Caulis Bambusae In Taenia 8-10 part, Bombyx Batryticatus 10-15 part, Radix Codonopsis 10-15 part.
The medicine of above-mentioned treatment epilepsy, optimum weight part proportioning of each raw material is:
Pericarpium Citri Reticulatae 15 parts, Rhizoma Pinelliae Preparatum 15 parts, Arisaema Cum Bile 12 parts, 12 parts of Poria, Rhizoma Acori Graminei 10 parts, Radix Polygalae 10 parts, Os Draconis 6 parts, the Rhizoma Atractylodis Macrocephalae 6 parts, Ramulus Uncariae Cum Uncis 15 parts, 6 parts of Radix Glycyrrhizae, Caulis Bambusae In Taenia 9 parts, Bombyx Batryticatus 12 parts, Radix Codonopsis 12 parts.
Described raw medicinal material is in shop of Chinese medicines and commercially available.
The preparation method of medicine of the present invention is as follows: weigh each raw material by weight ratio, add mixing to be placed in container, add the soak by water 3 times of material quantity weight 10-20 times again, decoct the soak by water 50-60min with 3-6 times every time, merge decoction liquor, filter and remove residue, it is the extractum of 1.20-1.40g that filtrate is concentrated into relative density at 60 DEG C, add adjuvant, make corresponding dosage form, to obtain final product.
In the present invention, the pharmacology of each crude drug, effect are as follows:
Pericarpium Citri Reticulatae: regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.For distension and fullness in the abdomen, lack of appetite and vomiting, cough with copious phlegm.
Rhizoma Pinelliae Preparatum: there is treatment drying dampness to eliminate phlegm, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, effect of syncope due to accumulation of phlegm headache.
Arisaema Cum Bile: clearing away fire and eliminating phlegm, relieving convulsion fixed chronic.Controlling middle wind-phlegm fan, infantile convulsion epilepsy, phlegm-fire is breathed heavily and is coughed, phlegm-accumulating vertigo.
Poria: promoting diuresis to eliminate damp pathogen, spleen invigorating, mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, loose stool has loose bowels, irritability, palpitation with fear insomnia.
Rhizoma Acori Graminei: reduce phlegm, has one's ideas straightened out, spleen invigorating, dampness removing.For epilepsy, palpitating with fear forgetful, obnubilation, humidity hysteresis painful abdominal mass is swollen, dysentery, rheumatalgia, carbuncle scabies.
Radix Polygalae: have Fructus Alpiniae Oxyphyllae of calming the nerves, the function eliminated the phlegm, subside a swelling, the insomnia and dreamful sleep caused for disarmony between the heart and kidney, forgetful palpitation with fear, staring spells, expectoration is not well, sore swollen toxin, breast swell and pain.
Os Draconis: tranquillization with heavy prescription tranquillizing the mind by relieving convulsion, arresting sweating controlling nocturnal emission with astringent drugs, stop blooding astringing intestine to stop diarrhea, promoting tissue regeneration and ulcer healing.Controlling infantile convulsion demented, palpitation with a distress feeling is forgetful, insomnia and dreamful sleep, spontaneous sweating, stranguria with turbid discharge of passing out semen, and tells nosebleed and has blood in stool, and bleeding not during menses, dysentery proctoptosis, ulcer does not closes up.
The Rhizoma Atractylodis Macrocephalae: invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.Have loose bowels for insufficiency of the spleen lack of appetite, abdominal distention, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.
Ramulus Uncariae Cum Uncis: heat clearing away suppressing the hyperactive liver;Relieving spasm by subduing liver-wind.Cure mainly: infantile convulsion;Night cry;Intenseness of heat wind symptom;Eclamposia;Dizziness due to hyperactivity of liver-YANG;Liver-fire distending pain in the head.
Radix Glycyrrhizae: QI invigorating invigorating middle warmer;Relieving spasm to stop pain;Nourishing the lung to arrest cough;Eliminating fire and detoxication;Coordinating the actions of various ingredients in a prescription.Main asthenia lack of appetite;Leanness yellowish complexion;Shortness of breath and palpitation;Stomachache loose stool;Extremity contraction urgency pain;Hysteria;Cough and asthma;Laryngopharynx swelling and pain;Ulcerative carbuncle swells and ache;Infantile carbuncle;And medicine, alimentary toxicosis.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, extremity contraction urgency pain, carbuncle sore tumefacting virus, cushion toxicity, strong.
Caulis Bambusae In Taenia: there is removing heat-phlegm, relieving restlessness, effect of preventing or arresting vomiting.For phlegm-heat cough, expectorant held under the arm by gallbladder fire, and palpitation with fear is not peaceful, vexed insomnia, middle wind-phlegm fan, aphasia with stiff tongue, gastropyretic vomiting, pregnancy reactions, frequent fetal movement.
Bombyx Batryticatus: be mainly used in convulsion with spasms, laryngopharynx swelling and pain, the diseases such as submandibular lymph nodes is scorching, facial paralysis, skin pruritus.
Radix Codonopsis: there is invigorating the spleen and replenishing QI, effect of strengthening spleen and tonifying lung.
The present invention treats the medicine of epilepsy, chooses 13 kinds of natural Chinese medicine scientific compatibility, and formula is simple, each crude drug synergism plays relieving convulsion, the effect of heat-clearing and toxic substances removing, relieving mental strain and helping sleep that clears away heart-fire, instant effect, treating both the principal and secondary aspects of a disease, have no side effect, and its preparation method is simple, taking convenience, low cost.
Detailed description of the invention
Below in conjunction with embodiment, present invention is further described, but is not limitation of the invention.
Embodiment 1
A kind of medicine treating epilepsy, the weight proportion of crude drug is:
Pericarpium Citri Reticulatae 12g, Rhizoma Pinelliae Preparatum 12g, Arisaema Cum Bile 10g, Poria 10g, Rhizoma Acori Graminei 8g, Radix Polygalae 8g, Os Draconis 5g, Rhizoma Atractylodis Macrocephalae 5g, Ramulus Uncariae Cum Uncis 12g, Radix Glycyrrhizae 5g, Caulis Bambusae In Taenia 8g, Bombyx Batryticatus 10g, Radix Codonopsis 10g.
Preparation method is as follows: is placed in container by above-mentioned raw materials mixing, then adds the soak by water 3 times of material quantity weight 10 times, every time with the soak by water 50min of 3 times, merging decoction liquor, filter and remove residue, it is the extractum of 1.20g that filtrate is concentrated into relative density at 60 DEG C, add adjuvant, make tablet, every 2g.
Embodiment 2
A kind of medicine treating epilepsy, the weight proportion of crude drug is:
Pericarpium Citri Reticulatae 15g, Rhizoma Pinelliae Preparatum 15g, Arisaema Cum Bile 12g, Poria 12g, Rhizoma Acori Graminei 10g, Radix Polygalae 10g, Os Draconis 6g, Rhizoma Atractylodis Macrocephalae 6g, Ramulus Uncariae Cum Uncis 15g, Radix Glycyrrhizae 6g, Caulis Bambusae In Taenia 9g, Bombyx Batryticatus 12g, Radix Codonopsis 12g.
Preparation method is as follows: is placed in container by above-mentioned raw materials mixing, then adds the soak by water 3 times of material quantity weight 15 times, every time with the soak by water 55min of 5 times, merging decoction liquor, filter and remove residue, it is the extractum of 1.30g that filtrate is concentrated into relative density at 60 DEG C, add adjuvant, make tablet, every 3g.
Embodiment 3
A kind of medicine treating epilepsy, the weight proportion of crude drug is:
Pericarpium Citri Reticulatae 18g, Rhizoma Pinelliae Preparatum 18g, Arisaema Cum Bile 15g, Poria 15g, Rhizoma Acori Graminei 12g, Radix Polygalae 12g, Os Draconis 7g, Rhizoma Atractylodis Macrocephalae 7g, Ramulus Uncariae Cum Uncis 18g, Radix Glycyrrhizae 8g, Caulis Bambusae In Taenia 10g, Bombyx Batryticatus 15g, Radix Codonopsis 15g.
Preparation method is as follows: is placed in container by above-mentioned raw materials mixing, then adds the soak by water 3 times of material quantity weight 20 times, every time with the soak by water 60min of 6.5 times, merging decoction liquor, filter and remove residue, it is the extractum of 1.40g that filtrate is concentrated into relative density at 60 DEG C, add adjuvant, make pill, every 5g.
In order to prove the clinical efficacy of Chinese medicine of the present invention further, select to accept 90 examples in patient for medical treatment, the curative effect of medicine of the present invention is carried out clinical observation.In age 10-60 year, being randomly divided into 3 groups, often group is 30 examples, respectively experimental group 1-3 group.
Experimental group 1-3 group takes the medicine of embodiment 1-3, three times a day, 3 slices/the most for oral administration respectively, within 10 days, is a course for the treatment of, takes 2 courses for the treatment of continuously.The most effective 85 examples, effective 84 examples, cure 80 examples, invalid 6 examples, cure rate 89%, effective percentage 93%.
Claims (3)
1. treat a medicine for epilepsy, it is characterized in that: be made up of the raw material of following weight parts proportioning:
Pericarpium Citri Reticulatae 12-18 part, Rhizoma Pinelliae Preparatum 12-18 part, Arisaema Cum Bile 10-15 part, Poria 10-15 part, Rhizoma Acori Graminei 8-12 part, Radix Polygalae 8-12 part, Os Draconis 5-7 part, Rhizoma Atractylodis Macrocephalae 5-7 part, Ramulus Uncariae Cum Uncis 12-18 part, Radix Glycyrrhizae 5-8 part, Caulis Bambusae In Taenia 8-10 part, Bombyx Batryticatus 10-15 part, Radix Codonopsis 10-15 part.
The medicine for the treatment of epilepsy the most according to claim 1, is made up of the raw material of following weight parts proportioning:
Pericarpium Citri Reticulatae 15 parts, Rhizoma Pinelliae Preparatum 15 parts, Arisaema Cum Bile 12 parts, 12 parts of Poria, Rhizoma Acori Graminei 10 parts, Radix Polygalae 10 parts, Os Draconis 6 parts, the Rhizoma Atractylodis Macrocephalae 6 parts, Ramulus Uncariae Cum Uncis 15 parts, 6 parts of Radix Glycyrrhizae, Caulis Bambusae In Taenia 9 parts, Bombyx Batryticatus 12 parts, Radix Codonopsis 12 parts.
The medicine for the treatment of epilepsy the most according to claim 1, is characterized in that:
Preparation method is as follows: weigh each raw material by weight ratio, add mixing to be placed in container, add the soak by water 3 times of material quantity weight 10-20 times again, every time with the soak by water 50-60min of 3-6 times, merge decoction liquor, filter and remove residue, it is the extractum of 1.20-1.40g that filtrate is concentrated into relative density at 60 DEG C, add adjuvant, make corresponding dosage form, to obtain final product.
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CN108201615A (en) * | 2016-12-20 | 2018-06-26 | 景金发 | Desinsection determines epilepsy preparation |
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CN1935251A (en) * | 2006-04-20 | 2007-03-28 | 任兰民 | Method for preparing Chinese medicine for treating epilepsy |
CN102988905A (en) * | 2012-12-28 | 2013-03-27 | 青岛华仁信息技术开发有限公司 | Traditional Chinese medicine preparation for treating epilepsia and preparation method thereof |
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- 2016-05-11 CN CN201610306973.7A patent/CN105770571A/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1935251A (en) * | 2006-04-20 | 2007-03-28 | 任兰民 | Method for preparing Chinese medicine for treating epilepsy |
CN102988905A (en) * | 2012-12-28 | 2013-03-27 | 青岛华仁信息技术开发有限公司 | Traditional Chinese medicine preparation for treating epilepsia and preparation method thereof |
Non-Patent Citations (1)
Title |
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雷子: "《常见病家庭医疗与护理 家庭常见病医疗保健》", 31 October 2006, 中医古籍出版社 * |
Cited By (1)
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CN108201615A (en) * | 2016-12-20 | 2018-06-26 | 景金发 | Desinsection determines epilepsy preparation |
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Application publication date: 20160720 |