CN105769127B - A kind of diagnostic equipment and its control method burnt based on copolymerization - Google Patents

A kind of diagnostic equipment and its control method burnt based on copolymerization Download PDF

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Publication number
CN105769127B
CN105769127B CN201610292231.3A CN201610292231A CN105769127B CN 105769127 B CN105769127 B CN 105769127B CN 201610292231 A CN201610292231 A CN 201610292231A CN 105769127 B CN105769127 B CN 105769127B
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laser
imaging
light source
treatment
diagnosis
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CN105769127A (en
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黄维
张运海
薛晓君
缪新
季林
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Suzhou Institute of Biomedical Engineering and Technology of CAS
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Suzhou Institute of Biomedical Engineering and Technology of CAS
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062Arrangements for scanning
    • A61B5/0068Confocal scanning
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/067Radiation therapy using light using laser light

Abstract

The present invention relates to a kind of diagnostic equipments and its control method burnt based on copolymerization, based on conjugate focus imaging technique, in laser light source, imaging laser light source and treatment laser light source are set, imaging pattern and treatment mode are provided, co-focusing imaging can be carried out to diagnosis and treatment region and analyzes the treatment region for needing to carry out laser therapy, it is switched to treatment and laser therapy is carried out to treatment region with laser light source, it is achieved and combines imaging diagnosis and laser therapy on one device, it does not need that different instruments is respectively adopted, operating process is easy, simultaneously using when focusing technology carries out laser therapy altogether, treatment region accurately can be positioned and be irradiated, unnecessary side effect and injury will not be brought to certain sensitizing ranges, substantially increase the therapeutic effect of laser, greatly it is conducive to promote.

Description

A kind of diagnostic equipment and its control method burnt based on copolymerization
Technical field
The present invention relates to field of medical device more particularly to a kind of diagnostic equipments and its control method burnt based on copolymerization.
Background technique
In recent years, being controlled with the development of laser technology by the diagnosing and treating means of tool, such as light power of laser The clinical value for the treatment of, laser beautifying etc. has at home and abroad been affirmed fully, and application range constantly extends.
But use laser for the diagnosing and treating of means at present, it needs to be respectively adopted different instrument complete independentlies, grasps Make requirements of process manpower intervention, and operating process is complicated;Meanwhile when using laser therapy, treatment region cannot be carried out accurate Irradiation, the irradiation of laser large area will cause the irradiation to certain sensitizing ranges and brings unnecessary side effect and injury, The therapeutic effect for substantially reducing laser is unfavorable for promoting.
Summary of the invention
In view of this, it is necessary to use laser to need to be respectively adopted different instrument for the diagnosing and treating of means for above-mentioned Device complete independently, provides a kind of based on altogether complicated for operation, cannot precisely irradiate, the problem of bringing unnecessary side effect and injury The diagnostic equipment of focusing.
Further, it would be desirable to provide the control methods of the above-mentioned diagnostic equipment burnt based on copolymerization.
A kind of diagnostic equipment burnt based on copolymerization provided by the invention, including laser light source, laser close beam system, laser tune System, beam splitting system, laser scanning system, micro- displacement system, faint light detection system and control system processed;
The laser light source includes to the diagnosis and treatment regional imaging laser light source and treatment laser on confocal plane Light source;
The laser closes beam system and is used to a variety of laser from institute's laser light source carrying out conjunction beam;
The Laser Modulation system is modulated the conjunction Shu Jiguang for closing beam system from the laser;
The beam splitting system for will laser scanning system described in the laser guide from the Laser Modulation system, and will Imaging optical signal from diagnosis and treatment region imports the faint light detection system;
The laser scanning system is used to receive the laser of the beam splitting system, and traverse the imaging on diagnosis and treatment region or Treatment region;
The micro- displacement system is for being displaced diagnosis and treatment region, to cover bigger diagnosis and treatment region;
The faint light detection system receives imaging optical signal that the beam splitting system imports, from diagnosis and treatment region, and Imaging optical signal is converted into electric signal;
The control system to the laser light source, Laser Modulation system, laser scanning system and micro- displacement system into Row control sets imaging laser light source for the laser light source in the imaging diagnosis stage, receives and visit from the faint light The electric signal of examining system carries out co-focusing imaging to diagnosis and treatment region, and electric signal is reconstructed into image and is analyzed and processed, and analyzes It needs to carry out the treatment region of laser therapy out, then treatment laser light source is set by the laser light source, to treatment region Domain carries out laser therapy.
Further, the Laser Modulation system pairing Shu Jiguang is modulated including multiwavelength laser gating modulation and each Wavelength amplitude modulation.
Further, the laser scanning system receives the laser from the beam splitting system, and with the side of laser facula The imaging of formula traversal or treatment region.
Further, the imaging region in diagnosis and treatment region is divided into multiple rectangular imaging sub-districts by the control system Each imaging subregion is moved in visual field using the micro- displacement system and carries out co-focusing imaging by domain.
Further, the control system determines the region for needing to carry out laser therapy in each imaging subregion, in institute Treatment laser light source is set by the laser light source after having imaging subregion to determine, laser is carried out to each subregion Treatment.
The control method of the above-mentioned diagnostic equipment burnt based on copolymerization of one kind provided by the invention, includes the following steps:
In the imaging diagnosis stage, imaging laser light source is set by laser light source, diagnosis and treatment region is focused into altogether Picture;
The image that co-focusing imaging obtains is analyzed, determines the treatment region treated;
Treatment laser light source is set by laser light source, laser therapy is carried out to treatment region.
Further, imaging or treatment region are traversed by the way of laser facula.
Further, before carrying out imaging diagnosis, by the imaging region in diagnosis and treatment region be divided into it is multiple it is rectangular at As subregion, and each imaging subregion is moved in visual field and carries out co-focusing imaging.
Further, described to set treatment laser light source for laser light source, laser therapy is carried out to treatment region Step specifically: determine the region for needing to carry out laser therapy in each imaging subregion, determined in all imaging subregions Treatment laser light source is set by laser light source after finishing, laser therapy is carried out to each subregion.
The present invention is based on the burnt diagnostic equipment of copolymerization and its control methods, conjugate focus imaging technique are based on, in laser light source Imaging laser light source and treatment laser light source are set, imaging pattern and treatment mode are provided, diagnosis and treatment region can be carried out Co-focusing imaging simultaneously analyzes the treatment region for needing to carry out laser therapy, be switched to treatment laser light source to treatment region into Row laser therapy is achieved and combines imaging diagnosis and laser therapy on one device, do not need to be respectively adopted different Instrument, operating process is easy, while using when focusing technology carries out laser therapy altogether, it is accurately fixed to carry out to treatment region Position and irradiation will not bring unnecessary side effect and injury to certain sensitizing ranges, substantially increase the therapeutic effect of laser, Greatly it is conducive to promote.
Detailed description of the invention
Fig. 1 is the structure chart based on the burnt diagnostic equipment of copolymerization in one embodiment.
Specific embodiment
In order to make the objectives, technical solutions, and advantages of the present invention clearer, with reference to the accompanying drawings and embodiments, right The present invention is further elaborated.It should be appreciated that described herein, specific examples are only used to explain the present invention, not For limiting the present invention.
Confocal microscopic image technology is the new and high technology that developed recently gets up, and is to study having for sub-micron fine structure Imitate the important tool of technological means and pathological research.It being capable of accurately high-resolution using confocal microscopic image technology The image for obtaining diagnosis and treatment region, obtains more accurate positioning and quantitative information, diagnoses conducive to diagnosis and treatment region.The present invention Equipment is based on laser scanning confocal microtechnic, and diagnosing and treating is combined on the same device, diagnosing and treating is avoided to adopt With being unable to technical problem brought by equipment.
Specifically, being that the structure chart based on the burnt diagnostic equipment of copolymerization in one embodiment should in conjunction with Fig. 1 as shown in Figure 1 Equipment includes: laser light source 100, laser conjunction beam system 200, Laser Modulation system 300, beam splitting system 400, laser scanning system 500, micro- displacement system 600, faint light detection system 700 and control system 800.Laser light source 100 includes in altogether Diagnosis and treatment region 10 imaging laser light source and treatment laser light source on focal plane.Laser closes beam system 200 for that will come from A variety of laser of laser light source 100 carry out conjunction beam.Laser Modulation system 300 is to the conjunction Shu Jiguang for closing beam system 200 from laser It is modulated.Beam splitting system 400 is used for the laser guide laser scanning system 500 of self-excitation in future light modulation system 300, and in the future Faint light detection system 700 is imported from the imaging optical signal in diagnosis and treatment region 10.Laser scanning system 500 is for receiving beam splitting system 400 laser, and traverse imaging or treatment region on diagnosis and treatment region 10.Micro- displacement system 600 is used for diagnosis and treatment region 10 are displaced, to cover bigger diagnosis and treatment region.Faint light detection system 700 receive beam splitting system 400 import, come from diagnosis and treatment The imaging optical signal in region 10, and imaging optical signal is converted into electric signal.Control system 800 is to laser light source 100, laser tune System 300, laser scanning system 500 and micro- displacement system processed are controlled, and set laser light source 100 in the imaging diagnosis stage It is set to imaging laser light source, the electric signal from faint light detection system 700 is received and diagnosis and treatment region 10 is focused into altogether Electric signal is reconstructed into image and is analyzed and processed by picture, analyzes the treatment region for needing to carry out laser therapy, then will be swashed Radiant 100 is set as treatment laser light source, carries out laser therapy to treatment region.In this way, present device is based on copolymerization Burnt imaging technique combines laser diagnostics and treatment on the same device, so that avoiding diagnosing and treating from using is unable to equipment institute The technical issues of bringing.
In further mode, 300 pairing Shu Jiguang of Laser Modulation system is modulated specifically: multiwavelength laser choosing Logical modulation and the modulation of each wavelength amplitude.
Laser scanning system 500 receives the laser from beam splitting system 400, and traversed in a manner of laser facula imaging or Person's treatment region.
For preferably diagnosis and treatment region 10 is imaged and is treated, control system 800 is by the imaging region in diagnosis and treatment region 10 Multiple rectangular imaging subregions are divided into, each imaging subregion is moved to imaging view using micro- displacement system 600 Yezhong carries out co-focusing imaging.
Control system 800 determines the region for needing to carry out laser therapy in each imaging subregion, in all imaging sub-districts Treatment laser light source is set by laser light source 100 after domain is determining, laser therapy is carried out to each subregion.
The diagnostic equipment burnt based on copolymerization is based on conjugate focus imaging technique, and imaging laser light is arranged in laser light source Source and treatment laser light source, provide imaging pattern and treatment mode, and co-focusing imaging can be carried out to diagnosis and treatment region and is analyzed The treatment region for needing to carry out laser therapy out is switched to treatment with laser light source and carries out laser therapy to treatment region, in this way It realizes and combines imaging diagnosis and laser therapy on one device, do not need that different instruments, operating process letter is respectively adopted Just, while using when focusing technology carries out laser therapy altogether, treatment region accurately can be positioned and is irradiated, will not be given Unnecessary side effect and injury are brought in certain sensitizing ranges, greatly improve the therapeutic effect of laser, are greatly conducive to promote.
Meanwhile the present invention also provides a kind of control method of above-mentioned diagnostic equipment burnt based on copolymerization, include the following steps:
In the imaging diagnosis stage, imaging laser light source is set by laser light source, diagnosis and treatment region is focused into altogether Picture.
Further, the mode of laser facula traverses imaging or treatment region.
Further, before carrying out imaging diagnosis, the imaging region in diagnosis and treatment region is divided into multiple rectangular Subregion is imaged, and each imaging subregion is moved in visual field and carries out co-focusing imaging.
The image that co-focusing imaging obtains is analyzed, determines the treatment region treated.
Treatment laser light source is set by laser light source, laser therapy is carried out to treatment region.
Further, step specifically: the region for needing to carry out laser therapy in each imaging subregion is determined, in institute Treatment laser light source is set by laser light source after having imaging subregion to determine, laser is carried out to each subregion and is controlled It treats.
The present invention is based on the burnt diagnostic equipment of copolymerization and its control methods, conjugate focus imaging technique are based on, in laser light source Imaging laser light source and treatment laser light source are set, imaging pattern and treatment mode are provided, diagnosis and treatment region can be carried out Co-focusing imaging simultaneously analyzes the treatment region for needing to carry out laser therapy, be switched to treatment laser light source to treatment region into Row laser therapy is achieved and combines imaging diagnosis and laser therapy on one device, do not need to be respectively adopted different Instrument, operating process is easy, while using when focusing technology carries out laser therapy altogether, it is accurately fixed to carry out to treatment region Position and irradiation will not bring unnecessary side effect and injury to certain sensitizing ranges, substantially increase the therapeutic effect of laser, Greatly it is conducive to promote.
The above is merely preferred embodiments of the present invention, be not intended to limit the invention, it is all in spirit of the invention and Made any modifications, equivalent replacements, and improvements etc., should all be included in the protection scope of the present invention within principle.

Claims (2)

1. a kind of diagnostic equipment burnt based on copolymerization, which is characterized in that close beam system, Laser Modulation including laser light source, laser System, beam splitting system, laser scanning system, micro- displacement system, faint light detection system and control system;
The laser light source includes to the diagnosis and treatment regional imaging laser light source and treatment laser light source on confocal plane;
The laser closes beam system and is used to a variety of laser from the laser light source carrying out conjunction beam, the Laser Modulation system Pairing Shu Jiguang is modulated including the modulation of multiwavelength laser gating and the modulation of each wavelength amplitude;
The Laser Modulation system is modulated the conjunction Shu Jiguang for closing beam system from the laser;
The beam splitting system for will laser scanning system described in the laser guide from the Laser Modulation system, and will come from The imaging optical signal in diagnosis and treatment region imports the faint light detection system;
The laser scanning system is used to receive the laser of the beam splitting system, and traverses imaging or treatment on diagnosis and treatment region Region;
The micro- displacement system is for being displaced diagnosis and treatment region, to cover bigger diagnosis and treatment region;
The faint light detection system receives imaging optical signal that the beam splitting system imports, from diagnosis and treatment region, and will be at As optical signal is converted to electric signal;
The control system controls the laser light source, Laser Modulation system, laser scanning system and micro- displacement system System sets imaging laser light source for the laser light source in the imaging diagnosis stage, receives and come from the faint light detection system The electric signal of system carries out co-focusing imaging to diagnosis and treatment region, and electric signal is reconstructed into image and is analyzed and processed, and analyzing needs Carry out the treatment region of laser therapy, then set treatment laser light source for the laser light source, to treatment region into Row laser therapy;
The imaging region in diagnosis and treatment region is divided into multiple rectangular imaging subregions by the control system, using described micro- Each imaging subregion is moved in visual field and carries out co-focusing imaging by displacement system;The control system determine it is each at The laser light source is arranged after all imaging subregions determine for region as needing to carry out laser therapy in subregion For treatment laser light source, laser therapy is carried out to each subregion.
2. the diagnostic equipment burnt based on copolymerization according to claim 1, which is characterized in that the laser scanning system receives Laser from the beam splitting system, and imaging or treatment region are traversed in a manner of laser facula.
CN201610292231.3A 2016-05-05 2016-05-05 A kind of diagnostic equipment and its control method burnt based on copolymerization Active CN105769127B (en)

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1549409A (en) * 2003-05-13 2004-11-24 应用生物光电科技股份有限公司 Quasi-phase matching photodynamic therapeutic and diagnostic laser light source
CN101972133A (en) * 2010-11-10 2011-02-16 天津市企美科技发展有限公司 Multifunctional fluorescence diagnosis and photodynamic therapy endoscopic diagnosis and treatment system
CN103190956A (en) * 2013-02-27 2013-07-10 胡建明 Laser therapeutic instrument based on OCT (optical coherence tomography) imaging system
WO2014207003A1 (en) * 2013-06-25 2014-12-31 Koninklijke Philips N.V. Measurement device for skin properties and non-invasive treatment device
CN205758514U (en) * 2016-05-05 2016-12-07 中国科学院苏州生物医学工程技术研究所 A kind of diagnostic equipment burnt based on copolymerization

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1549409A (en) * 2003-05-13 2004-11-24 应用生物光电科技股份有限公司 Quasi-phase matching photodynamic therapeutic and diagnostic laser light source
CN101972133A (en) * 2010-11-10 2011-02-16 天津市企美科技发展有限公司 Multifunctional fluorescence diagnosis and photodynamic therapy endoscopic diagnosis and treatment system
CN103190956A (en) * 2013-02-27 2013-07-10 胡建明 Laser therapeutic instrument based on OCT (optical coherence tomography) imaging system
WO2014207003A1 (en) * 2013-06-25 2014-12-31 Koninklijke Philips N.V. Measurement device for skin properties and non-invasive treatment device
CN205758514U (en) * 2016-05-05 2016-12-07 中国科学院苏州生物医学工程技术研究所 A kind of diagnostic equipment burnt based on copolymerization

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