CN105749233A - Prescription of traditional Chinese medicine for treating diabetes mellitus - Google Patents
Prescription of traditional Chinese medicine for treating diabetes mellitus Download PDFInfo
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- CN105749233A CN105749233A CN201610219887.2A CN201610219887A CN105749233A CN 105749233 A CN105749233 A CN 105749233A CN 201610219887 A CN201610219887 A CN 201610219887A CN 105749233 A CN105749233 A CN 105749233A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/56—Loganiaceae (Logania family), e.g. trumpetflower or pinkroot
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Abstract
The invention provides a prescription of a traditional Chinese medicine for treating diabetes mellitus, and relates to the field of traditional Chinese medicines. The traditional Chinese medicine is prepared from passiflora wilsonii hemsl, picris divaricata vaniot, processed semen strychni, raw ginger and licorice root. According to statistics, the traditional Chinese medicine can be used for remarkably improving fasting blood-glucose and related indexes of patients with diabetes mellitus and controlling the symptoms of complications, has an effective rate of 97.5 percent for patients with diabetes mellitus after being taken for 6-18 months; the blood glucose related indexes are normal after healing, and the cure rate is 93 percent. The prescription of the traditional Chinese medicine can be used for remarkably improving the immunity of patients with diabetes mellitus, stimulating pancreatic functions of patients and regulating metabolism of patients. In the process of using the prescription, patients cannot form drug dependence, and injury of traditional treatment methods on heart, liver, kidneys of patients can be avoided, so that the traditional Chinese medicine is a safe diabetes mellitus treatment medicine which can be taken for a long time and does not have toxic or side effect. The prescription has cured hundreds of patients with diabetes mellitus, and the earliest patient was cured before 8 years. During follow-up visit, the patients are not relapsed, and do not have sequela.
Description
Technical field
The present invention relates to tcm field, be specifically related to one and can regulate human immune system, excite the Chinese prescription of the treatment diabetes of pancreatic function.
Background technology
Diabetes are a kind of metabolic diseases being characterized with hyperglycemia caused by defect of insulin secretion or insulin action obstacle.Persistent high blood sugar and long-term metabolic are disorderly etc. may result in body tissue's organ, particularly eye, kidney, cardiovascular and neural infringement and dysfunction thereof and exhaustion.Severe patient can cause dehydration, the acute complications ketoacidosis such as electrolyte disturbance and acid base imbalance and Hyperosmotic coma.
The symptom of diabetes can be divided into two big classes: a big class is the performance relevant with metabolism disorder, especially relevant with hyperglycemia " three-many-one-little ", being more common in type 1 diabetes, type 2 diabetes mellitus is the most fairly obvious or only has part performance, and another big class is various acute, the performances of chronic complicating diseases.
1. polyuria, is owing to blood glucose is too high, exceedes renal glucose threshold (8.89~10.0mmol/L), the glucose leached through glomerule can not form osmotic diuresis completely by reabsorption, and blood glucose is the highest, glucose in urine excretion is the most, urine volume is the most, and 24h urine volume is up to 5000~10000ml, but old people and the person that has kidney disease, renal glucose threshold increases, glucose in urine acatharsia, when the light moderate of blood glucose increases, polyuria can be inconspicuous.
2. polydipsia, makes plasma osmotic pressure substantially increase mainly due to hyperglycemia, in addition polyuria, and loss of moist is too much, there is intracellular dehydration, increase the weight of hyperglycemia, make plasma osmotic pressure the most significantly raised, stimulating thirst center, cause thirsty and polydipsia, polydipsia increases the weight of polyuria further.
null3. polyphagia,The mechanism of polyphagia is the most fully aware of,Most scholar's tendencies are that glucose utilization rate (before and after turnover histiocyte, in arteriovenous blood, concentration of glucose is poor) reduces caused,In normal person's arteriovenous blood on an empty stomach, concentration of glucose difference reduces,Stimulate feeding center,Produce hunger sensation,After ingesting, blood glucose raises,Arteriovenous blood level difference strengthens (more than 0.829mmoL/L),Feeding center is suppressed,Satiety center is excited,Requirement of ingesting disappears,But diabetes patient due to the absolute of insulin or relatively lack or organizes insulin insensitivity,Tissue picked-up utilizes glucose ability to decline,Although blood glucose is in high level,But the concentration difference of glucose is the least in arteriovenous blood,Histiocyte is practically at " starvation ",Thus stimulate feeding center,Cause hunger,Polyphagia,Additionally,Body can not make full use of glucose,A large amount of glucoses are drained from urine,Therefore body is practically at semistarvation state,Energy deficiency also causes bulimia.
4. weight loss, although diabetics appetite and appetite are normal, even increase, but weight loss, definitely or relatively lack or insulin resistant mainly due to insulin, body can not make full use of glucose and produce energy, cause fat and breaks down proteins is strengthened, consume too much, in negative nitrogen balance, body weight is gradually reduced, or even occur becoming thin, once diabetes are through reasonably treatment, after obtaining good control, weight loss can control, go up, as diabetics continued weight over the course for the treatment of declines or substantially becomes thin, the possible Metabolism control of prompting is the best or merges other Chronic consumptionss.
The most weak, also it is common in diabetics, owing to glucose can not be fully oxidized, i.e. human body can not make full use of glucose and effectively give off energy, and organizes dehydration, electrolyte imbalance and negative nitrogen balance etc. simultaneously, thus feel malaise, lethargy.
6. visual deterioration, when many diabeticss are gone to a doctor in early days, main suit's visual deterioration or fuzzy, this mainly may cause crystalloid osmotic pressure to change with hyperglycemia, causes the change of crystal diopter caused, and the most general many function of dominants sexually revise, once blood glucose obtains good control, and vision can comparatively fast recover normal.
Group is more and more huger for diabetics, but Therapeutic Method does not has big breakthrough.The minimum patient of applicant's diagnosis and treatment 7 years old half, insulin injection a year and a half, say, that rise with regard to insulin injection for 6 years old, diabetes are not only brought great misery to patient, are caused great spiritual puzzlement the most also to the household of diabetics.
Western medical treatment diabetes, type 1 diabetes uses insulin injection to treat substantially, and type 2 diabetes mellitus can use western medicine, different according to mechanism of action, it is divided into Drugs Promoting Insulin Secretion (sulphanylureas, meglitinide), biguanides, Study of Thiazolidinedione derivatives as Insulin Sensitizer, alpha-glucosidase inhibitor, diyl peptidase-iv (VDPP-IV) inhibitor etc..Medicament selection should change insulin resistant and impaired insulin secretion considers by two main pathophysiological based on type 2 diabetes mellitus.Said medicine is treated, and can alleviate the series of problems caused by hyperglycemia to a certain extent, but the index of correlation about blood glucose in the patient has simply been interfered in its treatment, cures the symptoms, not the disease.Patient's Long-term taking medicine, can cause the damage of the organ functions such as heart, liver, kidney.Life-time service insulin, some meetings cause Drug resistance, and dosage is increasing, and worse and worse, related complication takes place frequently effect, even results in patient and dies from complication.
Diabetes Mellitus Treated With Traditional Chinese Medicine, also have a lot of prescription, but applicant is known maybe can contact, and therapeutic effect is not fully up to expectations.
Summary of the invention
For solving prior art Chinese medicine and western medicine, diabetes can only be taken stopgap measures, and the technical problem of Treated with Chinese Decoction DeGrain, the present invention provides a kind of Chinese prescription that can effectively treat diabetes.
A kind of Chinese prescription treating diabetes, including Herba Passiflorae Wilsonii, sharp knife Herba Sonchi Oleracei, Semen Strychni (processed), Rhizoma Zingiberis Recens, Radix Glycyrrhizae.
Above-mentioned prescription, when experienced Chinese traditional medical diagnose, needs according to patient's body constitution, change of illness state degree, and doctor drinks the relevant medical material quantity of state of an illness plus-minus.
In view of some patients can not be gone to a doctor at doctor, applicant is according to treating record for many years and summing up, proportioning in above-mentioned prescription is summed up consumption every day of universality (being suitable for most crowd), specific as follows: Herba Passiflorae Wilsonii 20-30g, sharp knife Herba Sonchi Oleracei 5-20g, Semen Strychni (processed) 1-3g, Rhizoma Zingiberis Recens 10-20g, Radix Glycyrrhizae 10-20g.
Further, the consumption of every day is as follows: Herba Passiflorae Wilsonii 24-26g, sharp knife Herba Sonchi Oleracei 10-15g, Semen Strychni (processed) 1.4-1.6g, Rhizoma Zingiberis Recens 14-16g, Radix Glycyrrhizae 14-16g.
Further, the each side such as receiving taking into account therapeutic effect, length medicine time, most patient's body constitution considers, when described every day, consumption was following, best results: Herba Passiflorae Wilsonii 25g, sharp knife Herba Sonchi Oleracei 13g, Semen Strychni (processed) 1.5g, Rhizoma Zingiberis Recens 15g, Radix Glycyrrhizae 15g.
Take after above-mentioned Chinese medicinal components is decocted water.
Also can directly take after above-mentioned Chinese medicinal components pulverizing, or after pulverizing, loading capsule be taken.Take after pulverizing and take effect slightly slowly compared to taking after pan-fried water, but general effect is better than pan-fried water and takes.
According to statistics, this prescription can obviously improve fasting glucose and the index of correlation of diabetics, controls complication symptom, and medication 6-18 month, the effective percentage to diabetics was 97.5%;After healing, blood glucose index of correlation is all normal, and cure rate is 93%.Chinese prescription disclosed in this invention can obviously improve the immunity of diabetics, excites the pancreatic function of patient, nurses one's health patient's own metabolism function.During using above-mentioned prescription, method is simple, easily operates, and patient will not form drug dependence, traditional therapy can be avoided simultaneously to patient's heart, liver, the damage of kidney, be a kind of safety, the Remedies for diabetes that long-term taking also has no side effect.From the point of view of a lot of patients, Chinese medicine is that it the most just considers, and applicant is as doctor among the people, mostly that is seen and treated patients is that patient and family members have the patient with severe symptoms of " giving up for lost " in arms, substantially have no idea just to carry out diagnosis and treatment, and above-mentioned prescription, cure hundreds of example diabetics, the longest having had 8 years away from the present of healing time, follows up a case by regular visits to cure patient all without recurring, without sequela.
Detailed description of the invention
Below in conjunction with representative model case, the present invention is described further:
Special instruction, when above-mentioned prescription is applied to clinic, the patient of more than 70%, the significantly rising of meeting once fasting glucose in the 15-45 days, although index rises, but patient is without any discomfort, and after two months, fasting glucose index gradually decreases to normal value.
The model case cured:
Case one, Huang, the generous people in Guizhou, female 63 years old, 14 years medical histories, can not walk with before the prescription medicine of the present invention, visual deterioration is to not regarding thing, fasting glucose 28.43, oral western medicine antidiabetic drug, medication 18 months, fasting glucose drops to 6.2, more after 4 years the most, quarterly survey blood glucose, without recurrence.
Case two, Wang, Anshun of Guizhou people, man 58 years old, 6 years medical histories, injection of insulin 4 years, weight loss 30 kilograms before the ill front prescription medicine arrived by the present invention, weak, visual deterioration, fasting glucose 19.27, medication 13 months, fasting glucose drops to 5.68, more after the most 2 years half, blood glucose is monthly surveyed, without recurrence.
Case three, permitted certain, people from Kweiyang, Guizhou, man 51 years old, 2 years medical histories, oral western medicine antidiabetic drug, readme becomes thin, weak, and drowsiness is many, whole body pruritus, fasting glucose 22.46, take the prescription medicine 20 days of the present invention, fasting glucose drops to 11.24, rebounds to 28.47 after February of taking medicine, and the 3rd month blood glucose is gradually reduced, 12nd month, fasting glucose dropped to 5.67, drug withdrawal 9 months, up to now, every first quarter moon surveys blood glucose, without recurrence.
The standard cured, the Index for examination that patient is relevant to blood glucose, nurse one's health in reference range through prescription medicine of the present invention, then the bimester of taking medicine, with examining blood glucose and index of correlation without repeatedly, get final product drug withdrawal.
Model case in treatment:
Case one, Wei, Anshun of Guizhou people, man 61 years old, 4 years medical histories, fasting glucose 12.59 before treatment, weak, few road, visual deterioration can only be walked, become thin, on May 21st, 15 rises and takes medicine 2 months, and blood glucose target rebounds to 25.75, but patient feels without discomfort, in JIUYUE, 15, fasting glucose drops to 11.26, in December, 2015, dropping to 6.75, specific targets and inspection data see table (particular exam report is detected by Anshun City, Guizhou Province the People's Hospital and provided):
Guo, female, 8 years old half, people of the Jin Dynasty are knitted in Guizhou, 2 years medical histories, injection of insulin a year and a half, fasting glucose 37.87 before treatment, after taking medicine, 9 days, i.e. stop the injection of insulin, after treating 40 days, in February, 2016, blood glucose drops to 6.06, and HbAle egg is 8.70, beyond reference range, medication treatment need to be continued, it is contemplated that within 6-9 month, get final product rehabilitation.
Statistical analysis finds, the time taking this prescription medicine also can be because being affected by geographical environment, and the time that the patient of high altitude localities takes medicine needed for fully recovering is longer, as a example by Guizhou, generally take medicine about 1 year and can fully recover, and as a example by the patient of Nanjing, take medicine about 6 months and can fully recover.
In the case of statistics, state of an illness approximation, the cycle short, between twenty and fifty without the patient treatment cycle of insulin injection is shorter than the treatment cycle of old people, child is the strongest to the adaptability of this prescription medicine, can fully recover about basic half a year to 1 year.
Protection scope of the present invention is not limited only to the technical scheme disclosed in patent application document, prescription disclosed in all utilizations, or a certain or replacement of several drugs equal authenticity medicine, or the trickle improvement to this prescription, each falls within protection scope of the present invention.
Claims (4)
1. treat a Chinese prescription for diabetes, including Herba Passiflorae Wilsonii, sharp knife Herba Sonchi Oleracei, Semen Strychni (processed), Rhizoma Zingiberis Recens, Radix Glycyrrhizae.
A kind of Chinese prescription treating diabetes the most according to claim 1, it is characterised in that: consumption every day of the proportioning in above-mentioned prescription is as follows: Herba Passiflorae Wilsonii 20-30g, sharp knife Herba Sonchi Oleracei 5-20g, Semen Strychni (processed) 1-3g, Rhizoma Zingiberis Recens 10-20g, Radix Glycyrrhizae 10-20g.
A kind of Chinese prescription treating diabetes the most according to claim 2, it is characterised in that: further, the consumption of every day is as follows: Herba Passiflorae Wilsonii 24-26g, sharp knife Herba Sonchi Oleracei 10-15g, Semen Strychni (processed) 1.4-1.6g, Rhizoma Zingiberis Recens 14-16g, Radix Glycyrrhizae 14-16g.
A kind of Chinese prescription treating diabetes the most according to claim 3, it is characterised in that: every day, consumption was as follows: Herba Passiflorae Wilsonii 25g, sharp knife Herba Sonchi Oleracei 13g, Semen Strychni (processed) 1.5g, Rhizoma Zingiberis Recens 15g, Radix Glycyrrhizae 15g.
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Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004045608A1 (en) * | 2002-11-15 | 2004-06-03 | Ranbaxy Laboratories Limited | Pharmaceutical compositions containing a biguanide-glitazone combination |
CN101057674A (en) * | 2007-06-13 | 2007-10-24 | 深圳市生物谷科技有限公司 | Composition for preventing and curing diabetes |
CN101301424A (en) * | 2008-06-20 | 2008-11-12 | 朱友文 | Chinese medicine composition for treating diabetes and method for preparing the same |
CN102028725A (en) * | 2010-12-22 | 2011-04-27 | 中国人民解放军第三○二医院 | Traditional Chinese medicine composition, extract, preparation method and application thereof |
CN102085227A (en) * | 2011-01-21 | 2011-06-08 | 山西医科大学 | Preparation with function of reducing blood sugar and preparation method thereof |
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- 2016-04-11 CN CN201610219887.2A patent/CN105749233A/en active Pending
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004045608A1 (en) * | 2002-11-15 | 2004-06-03 | Ranbaxy Laboratories Limited | Pharmaceutical compositions containing a biguanide-glitazone combination |
CN101057674A (en) * | 2007-06-13 | 2007-10-24 | 深圳市生物谷科技有限公司 | Composition for preventing and curing diabetes |
CN101301424A (en) * | 2008-06-20 | 2008-11-12 | 朱友文 | Chinese medicine composition for treating diabetes and method for preparing the same |
CN102028725A (en) * | 2010-12-22 | 2011-04-27 | 中国人民解放军第三○二医院 | Traditional Chinese medicine composition, extract, preparation method and application thereof |
CN102085227A (en) * | 2011-01-21 | 2011-06-08 | 山西医科大学 | Preparation with function of reducing blood sugar and preparation method thereof |
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Application publication date: 20160713 |