CN105749180A - 治疗心绞痛的中药组合物 - Google Patents

治疗心绞痛的中药组合物 Download PDF

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CN105749180A
CN105749180A CN201610293888.1A CN201610293888A CN105749180A CN 105749180 A CN105749180 A CN 105749180A CN 201610293888 A CN201610293888 A CN 201610293888A CN 105749180 A CN105749180 A CN 105749180A
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陈西河
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Abstract

本发明公开了一种治疗心绞痛的中药组合物，其中包含以下重量份的原料药：川连35、黄柏25、黄芩812、杭白芍812、郁金46、沙参812、清半夏58、川芎58、桃仁811、苏叶812、柴胡812、香附46、桔梗810、贝母58、草豆寇812、枳实0.81.5、丹参812、延胡索25、丹皮811以及赤芍812。本发明通过以上多种中药的合理配伍，清心肝之火、宣肺利膈、祛瘀止痛，使心绞痛得以治愈。

Description

治疗心绞痛的中药组合物
技术领域
本发明涉及中医药领域，尤其涉及一种治疗心绞痛的中药组合物。
背景技术
心绞痛（angina pectoris）是冠状动脉供血不足，心肌急剧的暂时缺血与缺氧所引起的以发作性胸痛或胸部不适为主要表现的临床综合征。多表现为闷痛、压榨性疼痛或胸骨后、咽喉部紧缩感，有些患者仅有胸闷，可分为典型性心绞痛和不典型性心绞痛。
现代医学认为心绞痛的直接发病原因是心肌供血的绝对或相对不足，因此，各种减少心肌血液（血氧）供应（如血管腔内血栓形成、血管痉挛）和增加氧消耗（如运动、心率增快）的因素，都可诱发心绞痛。西医用来治疗心绞痛的药物种类繁多，例如硝酸酯制剂、β受体阻断剂、钙通道阻滞剂、冠状动脉扩张剂等，一般起到扩张冠状动脉，降低阻力，增加血流量等作用，此类药物往往能暂时缓解，但是治标不治本，易反复发作，且具有一定的副作用。
发明内容
本发明针对现有技术中存在的上述问题，提供一种治疗心绞痛的中药组合物，能够从根本上有效治疗心绞痛，不易复发，无副作用。
为实现上述目的，本发明采用如下技术方案：
一种治疗心绞痛的中药组合物，包含以下重量份的原料药：
川连3-5、黄柏2-5、黄芩8-12、杭白芍8-12、郁金4-6、沙参8-12、清半夏5-8、川芎5-8、桃仁8-11、苏叶8-12、柴胡8-12、香附4-6、桔梗8-10、贝母5-8、草豆寇8-12、枳实0.8-1.5、丹参8-12、延胡索2-5、丹皮8-11以及赤芍8-12。
优选的是，所述的治疗心绞痛的中药组合物中，包含以下重量份的原料药：
川连4、黄柏3、黄芩10、杭白芍10、郁金5、沙参10、清半夏6、川芎6、桃仁9、苏叶10、柴胡10、香附5、桔梗9、贝母6、草豆寇10、枳实1、丹参10、延胡索3、丹皮9以及赤芍10。
本发明至少包括以下有益效果：本发明利用中医五行及辨证理论，认为心绞痛的病因为：心肝火旺，上逆于肺，肺气郁结，煎熬成饮，蓄积于胸膈，搏于心之分，故作痛。本发明中，川连，清心肝之火、解毒；黄柏，清肝、明目；黄芩，苦寒，燥湿泄热，并能解毒；杭白芍，平抑肝阳、养血敛阴；郁金，活血止痛、行气解郁、凉血清心；沙参，清肺养阴；清半夏，宣肺利膈；川芎，活血行气；桃仁，活血祛瘀；苏叶，行气宽中；柴胡、香附，疏肝解郁；桔梗，开宣肺气、祛瘀；贝母，祛痰饮；草豆寇，温中、行气；枳实，行气消痰、以通痞塞；丹参，活血祛瘀、养血安神；延胡索，活血、行气、止痛；丹皮，活血散瘀；赤芍，祛瘀止痛。本发明通过以上多种中药的合理配伍，清心肝之火、宣肺利膈、祛瘀止痛，使心绞痛得以治愈。
本发明根据对临床100例患者观察统计，按照每5-7剂为一个疗程，以每天一剂的用量连续服用5-10个疗程，治愈率92％，总有效率高达96%。
本发明的其它优点、目标和特征将部分通过下面的说明体现，部分还将通过对本发明的研究和实践而为本领域的技术人员所理解。
具体实施方式
下面对本发明做详细说明，以令本领域普通技术人员参阅本说明书后能够据以实施。
一种治疗心绞痛的中药组合物，包含以下重量份的原料药：川连3-5、黄柏2-5、黄芩8-12、杭白芍8-12、郁金4-6、沙参8-12、清半夏5-8、川芎5-8、桃仁8-11、苏叶8-12、柴胡8-12、香附4-6、桔梗8-10、贝母5-8、草豆寇8-12、枳实0.8-1.5、丹参8-12、延胡索2-5、丹皮8-11以及赤芍8-12。
本发明利用中医五行及辨证理论，认为心绞痛的病因为：心肝火旺，上逆于肺，肺气郁结，煎熬成饮，蓄积于胸膈，搏于心之分，故作痛。
本发明所述中药组合物的具体药理为：
川连，清心肝之火、解毒；
黄柏，清肝、明目；
黄芩，苦寒，燥湿泄热，并能解毒；
杭白芍，平抑肝阳、养血敛阴；
郁金，活血止痛、行气解郁、凉血清心；
沙参，清肺养阴；
清半夏，宣肺利膈；
川芎，活血行气；
桃仁，活血祛瘀；
苏叶，行气宽中；
柴胡、香附，疏肝解郁；
桔梗，开宣肺气、祛瘀；
贝母，祛痰饮；
草豆寇，温中、行气；
枳实，行气消痰、以通痞塞；
丹参，活血祛瘀、养血安神；
延胡索，活血、行气、止痛；
丹皮，活血散瘀；
赤芍，祛瘀止痛。
本发明通过以上多种中药的合理配伍，清心肝之火、宣肺利膈、祛瘀止痛，使心绞痛得以治愈。
实施例1
1、称取川连4克、黄柏3克、黄芩10克、杭白芍10克、郁金5克、沙参10克、清半夏6克、川芎6克、桃仁9克、苏叶10克、柴胡10克、香附5克、桔梗9克、贝母6克、草豆寇10克、枳实1克、丹参10克、延胡索3克、丹皮9克以及赤芍10克。
2、加入1.5倍体积的水浸泡20分钟，煮沸后文火熬制20-25分钟，滤出药液，得到第一滤液；
3、向药渣中重新加入等体积的水，煮沸后文火熬制30-35分钟，滤出药液得到第二滤液；
将第一滤液和第二滤液混合，每日一剂，每剂分两次服用，7剂为一个疗程，连续服用5个疗程。
实施例2
1、称取川连3克、黄柏4克、黄芩12克、杭白芍12克、郁金6克、沙参9克、清半夏5克、川芎5克、桃仁8克、苏叶12克、柴胡12克、香附6克、桔梗10克、贝母7克、草豆寇9克、枳实1.5克、丹参12克、延胡索2克、丹皮10克以及赤芍12克。
2、加入1.5倍体积的水浸泡20分钟，煮沸后文火熬制20-25分钟，滤出药液，得到第一滤液；
3、向药渣中重新加入等体积的水，煮沸后文火熬制30-35分钟，滤出药液得到第二滤液；
将第一滤液和第二滤液混合，每日一剂，每剂分两次服用，5剂为一个疗程，连续服用10个疗程
临床资料
1、疗效评价标准：
治愈：心绞痛症状消失。
显效：心绞痛症状明显减轻。
有效：心绞痛症状较治疗前减轻。
无效：病情无任何改善的表现。
2、治疗方案：
以川连3-5克、黄柏2-5克、黄芩8-12克、杭白芍8-12克、郁金4-6克、沙参8-12克、清半夏5-8克、川芎5-8克、桃仁8-11克、苏叶8-12克、柴胡8-12克、香附4-6克、桔梗8-10克、贝母5-8克、草豆寇8-12克、枳实0.8-1.5克、丹参8-12克、延胡索2-5克、丹皮8-11克以及赤芍8-12克为一剂用量，5-7剂为一个疗程，连续服用5-10个疗程。
3、治疗效果统计：
采用所述治疗方案对100例心绞痛患者进行治疗，并依据诊断标准进行统计。100例临床患者中，年龄最小35岁，最大67岁，平均年龄52岁，100例患者中，26人患病1年以内，46人患病1-3年，28人患病3年以上。经临床治疗，治愈92例，显效2例，有效2例，无效4例，治愈率92%，总有效率96%。
以上所述仅为本发明的实施方案，并非因此限制本发明的专利范围，凡是利用本发明说明书内容所作的等效结构或等效流程变换，或间接或直接运用在其他相关技术领域，均包括在本发明的专利保护范围内。

Claims (2)

1.一种治疗心绞痛的中药组合物，其特征在于，包含以下重量份的原料药：
川连3-5、黄柏2-5、黄芩8-12、杭白芍8-12、郁金4-6、沙参8-12、清半夏5-8、川芎5-8、桃仁8-11、苏叶8-12、柴胡8-12、香附4-6、桔梗8-10、贝母5-8、草豆寇8-12、枳实0.8-1.5、丹参8-12、延胡索2-5、丹皮8-11以及赤芍8-12。
2.如权利要求1所述的治疗心绞痛的中药组合物，其特征在于，包含以下重量份的原料药：
川连4、黄柏3、黄芩10、杭白芍10、郁金5、沙参10、清半夏6、川芎6、桃仁9、苏叶10、柴胡10、香附5、桔梗9、贝母6、草豆寇10、枳实1、丹参10、延胡索3、丹皮9以及赤芍10。
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CN103933474A (zh) * 2014-04-10 2014-07-23 成都中医药大学 一种治疗冠心病的药物组合物及其制备方法和用途
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