CN105748999A - Folium artemisiae argyi-contained Chinese medicine composition for treating cold erythema multiforme and preparation method thereof - Google Patents

Folium artemisiae argyi-contained Chinese medicine composition for treating cold erythema multiforme and preparation method thereof Download PDF

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CN105748999A
CN105748999A CN201610196474.7A CN201610196474A CN105748999A CN 105748999 A CN105748999 A CN 105748999A CN 201610196474 A CN201610196474 A CN 201610196474A CN 105748999 A CN105748999 A CN 105748999A
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chinese medicine
medicine composition
folium artemisiae
artemisiae argyi
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王飞
王一飞
刘宇坤
任哲
王巧利
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Guangzhou Jinan Biomedicine Research and Development Base Co Ltd
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Guangzhou Jinan Biomedicine Research and Development Base Co Ltd
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Abstract

The invention belongs to the technical field of Chinese medicine, and relates to a folium artemisiae argyi-contained Chinese medicine composition for treating cold erythema multiforme and preparation method thereof.The Chinese medicine composition is prepared from, by weight, 18-22 parts of folium artemisiae argyi, 16-20 parts of longhairy antenoron herbs, 15-19 parts of radix aconiti carmichaeli, 16-20 parts of tribulus terrestris, 11-15 parts of angelica sinensis, 10-14 parts of white peony root, 11-15 parts of lalang grass rhizome, 9-13 parts of fructus kochiae, 8-12 parts of tree peony bark, 8-12 parts of fructus forsythiae, 9-13 parts of Chinese taxillus herb and 7-11 parts of liquorice root.The Chinese medicine composition has the functions of clearing away heat and toxic materials, removing swelling and eliminating stasis, promoting blood circulation to remove blood stasis and warming channels to remove coldness, and has a remarkable treatment on cold erythema multiforme.

Description

Chinese medicine composition for the treatment of cold multiform erythema containing Folium Artemisiae Argyi and preparation method thereof
Technical field
The invention belongs to technical field of Chinese medicines, particularly relate to the Chinese medicine composition and preparation method thereof for the treatment of cold multiform erythema containing Folium Artemisiae Argyi.
Background technology
Cold multiform erythema is a kind of dermatosis being characterized with raw skin ulcer, the shape such as opal of skin, and the traditional Chinese medical science is referred to as erythema multiforme, for affection by exopathogenic cold-wind, battalion Defending discord, hematogenous blockage, cold coagulation is in caused by passages through which vital energy circulates.
This dermatosis occurrence frequency in winter is higher.Family's many installations air-conditioning, indoor/outdoor temperature-difference is big, and child is acral such as trick, buccal, auricle Deng blood vessel distal regulatory function more weak, occur that allergic inflammatory reacts, easily play purplish red pimple.Cold multiform erythema is common dermatosis in winter. When body under certain condition, to many reasons occur a kind of reactive inflammation performance, cold is topmost inducement;Infection, medicine, food Also can cause or make exacerbation of symptoms.
In terms of modern medicine angle, the morbidity of cold multiform erythema and cold have substantial connection, and mainly cold causes peripheral blood circulation obstacle, And it is relevant with immunoreation.Chinese medicine thinks that primary disease belongs to " erythema multiforme ", " erythema multiforme " category, comes from natural endowment more and is weak to, and innate deficiency of YANG in the body, wind and cold is invaded Attack, strongly fragrant in skin, visitor in passages through which vital energy circulates, qi stagnation hemagglutination, passages through which vital energy circulates impatency, the stasis of blood and be skin ulcer.Pathogenesis predominantly " yang deficiency ", " wind and cold ", " blood stasis " three Aspect." Plain Questions regulating menstruation opinion " is said: " QI and blood person, happiness temperature and aversion to cold, cold then weep and do not flow, Wen Ze disappears and goes.
Chinese patent application 201310605424.6 discloses a kind of Chinese medicine treating erythema multiforme, is by Radix Codonopsis 13-17 gram, 8-12 gram of Semen Persicae, Semen Cuscutae 10-14 gram, Cortex Cinnamomi 7-11 gram, Herba Asari 18-22 gram, Fructus Liquidambaris 23-27 gram, Radix Clematidis 20-24 gram, 16-20 gram of Radix Rubiae, Herba Lycopi 8-12 gram is prepared from, and this invention Chinese medicine clinic can treat erythema multiforme.This Chinese medicine has no side effect, but drug effect is failed to understand, and to col multiform Erythema does not has specific aim.
Summary of the invention
The technical problem to be solved in the present invention is to provide the Chinese medicine composition of the treatment cold multiform erythema containing Folium Artemisiae Argyi, and this Chinese medicine composition has heat clearing away Removing toxic substances, dispersing swelling and dissipating binds, blood circulation promoting and blood stasis dispelling, effect of dispelling cold by warming the meridian, also there is good effect, have no side effect and the advantage such as taking convenience.Additionally, this Invention also provides for corresponding manufacturing process and this Chinese medicine composition is facilitated easy-to-use preparation ensureing to make on the premise of curative effect.
For achieving the above object, the technical scheme that the present invention takes is as follows:
Chinese medicine composition of the present invention is prepared from by the raw material of following parts by weight:
Folium Artemisiae Argyi 18-22 part, Herba Lysimachiae 16-20 part, Radix Aconiti Lateralis Preparata 15-19 part, Fructus Atriplicis Sibiricae 16-20 part, Radix Angelicae Sinensis 11-15 part, Radix Paeoniae 10-14 part, white Rhizoma Imperatae 11-15 part, Fructus Kochiae 9-13 part, Cortex Moutan 8-12 part, Fructus Forsythiae 8-12 part, Herba Taxilli 9-13 part and Radix Glycyrrhizae 7-11 part.
Further, described Chinese medicine composition is prepared from by the raw material of following parts by weight:
Folium Artemisiae Argyi 18 parts, Herba Lysimachiae 16 parts, Radix Aconiti Lateralis Preparata 15 parts, Fructus Atriplicis Sibiricae 16 parts, Radix Angelicae Sinensis 11 parts, Radix Paeoniae 10 parts, Rhizoma Imperatae 11 parts, Fructus Kochiae Son 9 parts, Cortex Moutan 8 parts, Fructus Forsythiae 8 parts, Herba Taxilli 9 parts and 7 parts of Radix Glycyrrhizae.
Further, described Chinese medicine composition is prepared from by the raw material of following parts by weight:
Folium Artemisiae Argyi 22 parts, Herba Lysimachiae 20 parts, Radix Aconiti Lateralis Preparata 19 parts, Fructus Atriplicis Sibiricae 20 parts, Radix Angelicae Sinensis 15 parts, Radix Paeoniae 14 parts, Rhizoma Imperatae 15 parts, Fructus Kochiae Son 13 parts, Cortex Moutan 12 parts, Fructus Forsythiae 12 parts, Herba Taxilli 13 parts and 11 parts of Radix Glycyrrhizae.
Further, described Chinese medicine composition is prepared from by the raw material of following parts by weight:
Folium Artemisiae Argyi 20 parts, Herba Lysimachiae 18 parts, Radix Aconiti Lateralis Preparata 17 parts, Fructus Atriplicis Sibiricae 18 parts, Radix Angelicae Sinensis 13 parts, Radix Paeoniae 12 parts, Rhizoma Imperatae 13 parts, Fructus Kochiae Son 11 parts, Cortex Moutan 10 parts, Fructus Forsythiae 10 parts, Herba Taxilli 11 parts and 9 parts of Radix Glycyrrhizae.
Further, described Chinese medicine composition is made into capsule, tablet, powder, oral liquid, granule or pill.
Correspondingly, the preparation method of described Chinese medicine composition comprises following step:
S1, weigh each taste raw medicinal material in proportion;
S2, by Folium Artemisiae Argyi, Herba Lysimachiae, Radix Aconiti Lateralis Preparata, Fructus Atriplicis Sibiricae, Radix Angelicae Sinensis, Radix Paeoniae, Rhizoma Imperatae, the Fructus Kochiae, Cortex Moutan, Fructus Forsythiae, Herba Taxilli and Radix Glycyrrhizae Decontamination respectively, cleans, and dries, is ground into coarse powder;
S3, the ingredients coarse powder prepared by S2 mix, and add the distilled water of initial 5-8 times of weight of medical material, soak 12-20 hour, decoct 2-4 Hour, filter and retain filtrate;Add the purified water of initial 6-9 times of weight of medical material, decoct 1-3 hour, filter;Merging filtrate, is concentrated into 60-70 DEG C of relative density is that the Chinese medical concrete of 1.30-1.35 is standby;
S4, toward the Chinese medical concrete of S3 gained adds adjuvant, utilize modern general Chinese medicine composition technology to make the finished product preparation of clinical needs.
The source of component used by the present invention, nature and flavor, return through and effect:
Folium Artemisiae Argyi: for the dried leaves of feverfew Chinese mugwort;Acrid in the mouth, hardship, warm in nature, return liver,spleen,kidney warp;Warming the meridian for stopping bleeding, dispersing cold for relieving pain, regulating menstruation is pacified Tire, removing damp to relieve itching, dredge the meridian passage.
Herba Lysimachiae: for the dry herb of Ofthe Primulaceae Lysimachia christinae Hance;Sweet in the mouth, salty, cold nature;Return liver, gallbladder, kidney, bladder warp;Eliminating damp-heat, Treating stranguria, detumescence.
Radix Aconiti Lateralis Preparata: for the processed goods of the daughter root of ranunculaceae plant Aconitum carmichjaelii Debx.;Acrid in the mouth, sweet, extremely hot in nature;GUIXIN, kidney, spleen channel;Recuperating depleted YANG and rescuing the patient from collapse, mends fire and helps Sun, by wind-cold damp pathogen.
Fructus Atriplicis Sibiricae: for the fruit of zygophyllaceae plant Fructus Tribuli;Bitter in the mouth, pungent, warm in nature;Return liver, lung meridian;Dissipate wind, improving eyesight, the therapeutic method to keep the adverse QI flowing downwards, promoting the circulation of blood.
Radix Angelicae Sinensis: for the dry root of umbelliferae angelica;Sweet in the mouth, pungent, warm in nature;Return liver, the heart, spleen channel;Inrigorating qi and promoting blood circulation, menstruction regulating and pain relieving, intestine moistening Relieving constipation.
Radix Paeoniae: for the dry root of ranunculaceae plant Radix Paeoniae;Bitter in the mouth, property is put down;Return liver, spleen channel;Suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating.
Rhizoma Imperatae: for the dry rhizome of grass Herba Imperatae;Sweet in the mouth, cold in nature;Return lung, stomach, bladder warp;Cooling blood for hemostasis, heat clearing away profit Urine.
The Fructus Kochiae: for the dry mature fruit of chenopod Fructus Kochiae;Acrid in the mouth, hardship, cold in nature;Return kidney, bladder warp;Clearing away heat-damp and promoting diuresis, dispelling wind for relieving itching.
Cortex Moutan: for the dry root bark of ranunculaceae peony;Bitter in the mouth, pungent, cold nature;GUIXIN, liver, kidney channel;Clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.
Fructus Forsythiae: for the dry fruit of Oleaceae plants Fructus Forsythiae;Bitter in the mouth, cold nature;Return lung, the heart, small intestine meridian;Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.
Herba Taxilli: for the dry stem and branch with leaf of Loranthaceae plant Herba Taxilli;Bitter in the mouth, sweet, property is put down;Return liver, kidney channel;Invigorating the liver and kidney, bone and muscle strengthening, Wind-damp dispelling, antiabortive unit.
Radix Glycyrrhizae: this product is the dry root of glycyrrhizic legume, Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L..Sweet in the mouth, property is put down;GUIXIN, lung, spleen, stomach warp;Mend Spleen QI invigorating, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.
The prescription analysis of Chinese medicine of the present invention:
According to the traditional Chinese medical science to the dialectical of cold multiform erythema and the compatibility theory of Chinese crude drug, in conjunction with body constitution and the spy of modern pharmaceutical technology of modern Point, the collocation ingredients of reasonable science, form Chinese prescription of the present invention.The prescription of the present invention is with Folium Artemisiae Argyi as monarch drug, dispelling cold by warming the meridian, work of stimulating the menstrual flow Network;With Herba Lysimachiae, Radix Aconiti Lateralis Preparata, Fructus Atriplicis Sibiricae and when being classified as ministerial drug, by wind-cold damp pathogen, inrigorating qi and promoting blood circulation;With Radix Paeoniae, Rhizoma Imperatae, the Fructus Kochiae, Cortex Moutan, Fructus Forsythiae and Herba Taxilli are adjuvant drug, blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing, dispersing swelling and dissipating binds;With Radix Glycyrrhizae for making medicine, invigorating the spleen and replenishing QI, coordinating the actions of various ingredients in a prescription;Monarch All medicines coordinate, collaborative promotion, complement each other, are finally reached, and dispersing cold for relieving pain mends fire supporing yang, blood circulation promoting and blood stasis dispelling, effect of dispelling cold by warming the meridian, it is adaptable to Treatment cold multiform erythema disease.
Compared with prior art, the present invention has a following technical advantage:
1, Chinese medicine composition of the present invention is compared with the medicine of other treatment treatment cold multiform erythema, in terms of by wind-cold damp pathogen, has significantly Effect, clinical test results shows, Chinese medicine composition of the present invention can significantly alleviate and eliminate the skin lesion symptom of cold multiform erythema volunteer patients, Curative effect is substantially better than matched group, and relapse rate is low, without obvious adverse reaction during medication.
2, compared with the chemotherapeutic agent of Current therapeutic cold multiform erythema, the prescription of Chinese medicine composition of the present invention is the medical material of pure natural, no Good reaction is less and side effect is low, and comprehensively, therapeutic effect more preferably, efficiently solves the morbidity root of cold multiform erythema, and improves trouble in effect The quality of life of person.
3, Chinese medicine composition of the present invention also has compatibility science, cure rate is high, be difficult to the advantages such as recurrence.
Detailed description of the invention
It will be understood by those skilled in the art that technology disclosed in following example represents the performance in the practice of the invention that the inventors discovered that good The technology of effect.But, disclosed specific embodiments can be made many changes, and still obtain same or analogous result, and not Depart from the spirit and scope of the present invention.
Embodiment 1
The embodiment of the present invention 1 Chinese medicine composition is prepared from by the raw material of following parts by weight: Folium Artemisiae Argyi 18 parts, Herba Lysimachiae 16 parts, Radix Aconiti Lateralis Preparata 15 parts, Fructus Atriplicis Sibiricae 16 parts, Radix Angelicae Sinensis 11 parts, Radix Paeoniae 10 parts, Rhizoma Imperatae 11 parts, the Fructus Kochiae 9 parts, Cortex Moutan 8 parts, Fructus Forsythiae 8 parts, Herba Taxilli 9 parts With 7 parts of Radix Glycyrrhizae.
Preparation method is as follows:
S1, weigh each taste raw medicinal material in proportion;
S2, by Folium Artemisiae Argyi, Herba Lysimachiae, Radix Aconiti Lateralis Preparata, Fructus Atriplicis Sibiricae, Radix Angelicae Sinensis, Radix Paeoniae, Rhizoma Imperatae, the Fructus Kochiae, Cortex Moutan, Fructus Forsythiae, Herba Taxilli and Radix Glycyrrhizae Decontamination respectively, cleans, and dries, is ground into coarse powder;
S3, the ingredients coarse powder prepared by S2 mix, and add the distilled water of initial 5 times of weight of medical material, soak 16 hours, decoct 3 hours, Filter and retain filtrate;Add the purified water of initial 8 times of weight of medical material, decoct 2 hours, filter;Merging filtrate, be concentrated into 65 DEG C the closeest Degree be 1.35 Chinese medical concrete standby;
S4, toward the Chinese medical concrete of S3 gained adds adjuvant, utilize modern general Chinese medicine composition technology to make capsule, every capsule medicated amount For 0.4g.
Embodiment 2
The embodiment of the present invention 2 Chinese medicine composition is prepared from by the raw material of following parts by weight: Folium Artemisiae Argyi 22 parts, Herba Lysimachiae 20 parts, Radix Aconiti Lateralis Preparata 19 parts, Fructus Atriplicis Sibiricae 20 parts, Radix Angelicae Sinensis 15 parts, Radix Paeoniae 14 parts, Rhizoma Imperatae 15 parts, the Fructus Kochiae 13 parts, Cortex Moutan 12 parts, Fructus Forsythiae 12 parts, Herba Taxilli 13 parts and 11 parts of Radix Glycyrrhizae.
Preparation method is with embodiment 1.
Embodiment 3
The embodiment of the present invention 3 Chinese medicine composition is prepared from by the raw material of following parts by weight: Folium Artemisiae Argyi 20 parts, Herba Lysimachiae 18 parts, Radix Aconiti Lateralis Preparata 17 parts, Fructus Atriplicis Sibiricae 18 parts, Radix Angelicae Sinensis 13 parts, Radix Paeoniae 12 parts, Rhizoma Imperatae 13 parts, the Fructus Kochiae 11 parts, Cortex Moutan 10 parts, Fructus Forsythiae 10 parts, Herba Taxilli 11 parts and 9 parts of Radix Glycyrrhizae.
Preparation method is with embodiment 1.
Embodiment 4
The embodiment of the present invention 4 Chinese medicine composition is prepared from by the raw material of following parts by weight: Folium Artemisiae Argyi 19 parts, Herba Lysimachiae 17 parts, Radix Aconiti Lateralis Preparata 16 parts, Fructus Atriplicis Sibiricae 17 parts, Radix Angelicae Sinensis 12 parts, Radix Paeoniae 11 parts, Rhizoma Imperatae 12 parts, the Fructus Kochiae 10 parts, Cortex Moutan 9 parts, Fructus Forsythiae 9 parts, Herba Taxilli 10 Part and 8 parts of Radix Glycyrrhizae.
Preparation method is with embodiment 1.
Embodiment 5
The embodiment of the present invention 5 Chinese medicine composition is prepared from by the raw material of following parts by weight: Folium Artemisiae Argyi 21 parts, Herba Lysimachiae 19 parts, Radix Aconiti Lateralis Preparata 18 parts, Fructus Atriplicis Sibiricae 19 parts, Radix Angelicae Sinensis 14 parts, Radix Paeoniae 13 parts, Rhizoma Imperatae 14 parts, the Fructus Kochiae 12 parts, Cortex Moutan 11 parts, Fructus Forsythiae 11 parts, Herba Taxilli 12 parts and 10 parts of Radix Glycyrrhizae.
Preparation method is with embodiment 1.
The Chinese medicine composition of the present invention observation of curative effect to cold multiform erythema clinical volunteers patient
One, diagnostic criteria
Determine with reference to according to " the Chinese medical disease Standardization of diagnosis and curative effect " of State Administration of Traditional Chinese Medicine's distribution:
When 1, being apt to occur in Winter-Spring cold;
2, skin lesion is mainly in erythema multiforme sample pimple even vesicle, petechiae;
3, skin lesion is apt to occur in face, ear, distal limbs exposure portion;
4, temperature can spontaneous remission after raising;
5, the conscious pruritus of skin lesion.
Two, criterion of therapeutical effect
Determine with reference to according to " the Chinese medical disease Standardization of diagnosis and curative effect " of State Administration of Traditional Chinese Medicine's distribution:
Curing: skin lesion all disappears, subjective symptoms disappears;
Effective: skin lesion disappears more than 30%, and subjective symptoms substantially alleviates;
Invalid: skin lesion disappears less than 30%, still there is new rash to occur.
Three, clinical trial
1. physical data
The cold multiform erythema clinical volunteers patient that 720 are selected is divided into 6 groups at random, often organizes 120 people, be respectively treatment A-E group with Matched group, respectively organizes the influence factor such as age, symptom, through statistical procedures, there was no significant difference, and meets packet condition.
2. Therapeutic Method
Test A-E group: take the capsule (0.4g*60 grain/bottle) that embodiment of the present invention 1-5 prepares, every day 2 times respectively, each 3, connect Take one month;
Matched group: take Baixuan Xiatare Capsule (Dongtai Pharmaceutical Co., Ltd., Shaanxi Prov., traditional Chinese medicines quasi-word Z20050139,0.4g*12 grain/box), once 2,3 times on the one, it serve on one month.
3. therapeutic outcome, as shown in table 1.
Table 1 therapeutic effect
Group Number of cases Cure (rate) Effectively Invalid Total effective rate
Test A group 120 88 (73.3%) 16 16 86.7%
Test B group 120 86 (71.7%) 19 15 87.5%
Test C group 120 92 (76.7%) 15 13 89.2%
Test D group 120 85 (70.8%) 18 17 85.8%
Test E group 120 87 (72.5%) 18 15 87.5%
Matched group 120 82 (68.3%) 20 18 85.0%
This test uses Baixuan Xiatare Capsule as a control group, and Baixuan Xiatare Capsule is by dragon Herba Euphorbiae Humifusae, terminalia flesh, Fructus Terminaliae Billericae, Si Kamoni The Chinese medicines such as sub-fat, Aloe, FRUCTUS TERMINALIAE IMMATURUS meticulously refine and form, and have effect of repellent antipruritic, can be clinically used for treating cold multiform erythema.From Can be seen that on cure rate and total effective rate, the cure rate of Chinese medicine composition of the present invention and total effective rate respectively reach 70% and more than 80%, hence it is evident that be higher than Matched group, and best with the test C group i.e. therapeutic effect of the capsule that the embodiment of the present invention 3 prepares.Clinical trial results proves Chinese medicine composition of the present invention Thing treatment cold multiform erythema effect is notable, has heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, blood circulation promoting and blood stasis dispelling, the curative effect of dispelling cold by warming the meridian, can control as clinic Treating cold multiform erythema drug use, clinical generalization value is high.
Owing to describing the present invention by above preferred embodiment, in the spirit and/or scope of the present invention, any replacement for the present invention/ Or combination implement the present invention, will be apparent from for a person skilled in the art, and be included among the present invention.

Claims (7)

1. the Chinese medicine composition of the treatment cold multiform erythema containing Folium Artemisiae Argyi, it is characterised in that described Chinese medicine composition is former by following parts by weight Material is prepared from:
Folium Artemisiae Argyi 18-22 part, Herba Lysimachiae 16-20 part, Radix Aconiti Lateralis Preparata 15-19 part, Fructus Atriplicis Sibiricae 16-20 part, Radix Angelicae Sinensis 11-15 part, Radix Paeoniae 10-14 part, white Rhizoma Imperatae 11-15 part, Fructus Kochiae 9-13 part, Cortex Moutan 8-12 part, Fructus Forsythiae 8-12 part, Herba Taxilli 9-13 part and Radix Glycyrrhizae 7-11 part.
2. the Chinese medicine composition of the treatment cold multiform erythema containing Folium Artemisiae Argyi as claimed in claim 1, it is characterised in that described Chinese medicine composition It is prepared from by the raw material of following parts by weight:
Folium Artemisiae Argyi 18 parts, Herba Lysimachiae 16 parts, Radix Aconiti Lateralis Preparata 15 parts, Fructus Atriplicis Sibiricae 16 parts, Radix Angelicae Sinensis 11 parts, Radix Paeoniae 10 parts, Rhizoma Imperatae 11 parts, Fructus Kochiae Son 9 parts, Cortex Moutan 8 parts, Fructus Forsythiae 8 parts, Herba Taxilli 9 parts and 7 parts of Radix Glycyrrhizae.
3. the Chinese medicine composition of the treatment cold multiform erythema containing Folium Artemisiae Argyi as claimed in claim 1, it is characterised in that described Chinese medicine composition It is prepared from by the raw material of following parts by weight:
Folium Artemisiae Argyi 22 parts, Herba Lysimachiae 20 parts, Radix Aconiti Lateralis Preparata 19 parts, Fructus Atriplicis Sibiricae 20 parts, Radix Angelicae Sinensis 15 parts, Radix Paeoniae 14 parts, Rhizoma Imperatae 15 parts, Fructus Kochiae Son 13 parts, Cortex Moutan 12 parts, Fructus Forsythiae 12 parts, Herba Taxilli 13 parts and 11 parts of Radix Glycyrrhizae.
4. the Chinese medicine composition of the treatment cold multiform erythema containing Folium Artemisiae Argyi as claimed in claim 1, it is characterised in that described Chinese medicine composition It is prepared from by the raw material of following parts by weight:
Folium Artemisiae Argyi 20 parts, Herba Lysimachiae 18 parts, Radix Aconiti Lateralis Preparata 17 parts, Fructus Atriplicis Sibiricae 18 parts, Radix Angelicae Sinensis 13 parts, Radix Paeoniae 12 parts, Rhizoma Imperatae 13 parts, Fructus Kochiae Son 11 parts, Cortex Moutan 10 parts, Fructus Forsythiae 10 parts, Herba Taxilli 11 parts and 9 parts of Radix Glycyrrhizae.
5. the Chinese medicine composition of the treatment cold multiform erythema containing Folium Artemisiae Argyi as described in claim 1-4 is arbitrary, it is characterised in that described Chinese drug-treated group Compound is made into capsule, tablet, powder, oral liquid, granule or pill.
6. the Chinese medicine composition of the treatment cold multiform erythema containing Folium Artemisiae Argyi as described in claim 1-4 is arbitrary, it is characterised in that described Chinese medicine The preparation method of compositions comprises following step:
S1, weigh each taste raw medicinal material in proportion;
S2, by Folium Artemisiae Argyi, Herba Lysimachiae, Radix Aconiti Lateralis Preparata, Fructus Atriplicis Sibiricae, Radix Angelicae Sinensis, Radix Paeoniae, Rhizoma Imperatae, the Fructus Kochiae, Cortex Moutan, Fructus Forsythiae, Herba Taxilli and Radix Glycyrrhizae Decontamination respectively, cleans, and dries, is ground into coarse powder;
S3, the ingredients coarse powder prepared by S2 mix, and add the distilled water of initial 5-8 times of weight of medical material, soak 12-20 hour, decoct 2-4 Hour, filter and retain filtrate;Add the purified water of initial 6-9 times of weight of medical material, decoct 1-3 hour, filter;Merging filtrate, is concentrated into 60-70 DEG C of relative density is that the Chinese medical concrete of 1.30-1.35 is standby;
S4, toward the Chinese medical concrete of S3 gained adds adjuvant, utilize modern general Chinese medicine composition technology to make the finished product preparation of clinical needs.
7. the method for the Chinese medicine composition preparing the treatment cold multiform erythema containing Folium Artemisiae Argyi as claimed in claim 1, it is characterised in that Comprise following step:
S1, weigh each taste raw medicinal material in proportion;
S2, by Folium Artemisiae Argyi, Herba Lysimachiae, Radix Aconiti Lateralis Preparata, Fructus Atriplicis Sibiricae, Radix Angelicae Sinensis, Radix Paeoniae, Rhizoma Imperatae, the Fructus Kochiae, Cortex Moutan, Fructus Forsythiae, Herba Taxilli and Radix Glycyrrhizae Decontamination respectively, cleans, and dries, is ground into coarse powder;
S3, the ingredients coarse powder prepared by S2 mix, and add the distilled water of initial 5-8 times of weight of medical material, soak 12-20 hour, decoct 2-4 Hour, filter and retain filtrate;Add the purified water of initial 6-9 times of weight of medical material, decoct 1-3 hour, filter;Merging filtrate, is concentrated into 60-70 DEG C of relative density is that the Chinese medical concrete of 1.30-1.35 is standby;
S4, toward the Chinese medical concrete of S3 gained adds adjuvant, utilize modern general Chinese medicine composition technology to make the finished product preparation of clinical needs.
CN201610196474.7A 2016-03-31 2016-03-31 Folium artemisiae argyi-contained Chinese medicine composition for treating cold erythema multiforme and preparation method thereof Pending CN105748999A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105169342A (en) * 2015-10-12 2015-12-23 临沂草之美医药科技有限公司 Traditional Chinese medicine composition for treating eczema and preparation method thereof
CN105381338A (en) * 2015-11-27 2016-03-09 黄德禄 Group of medicines for treating erythema multiforme

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105169342A (en) * 2015-10-12 2015-12-23 临沂草之美医药科技有限公司 Traditional Chinese medicine composition for treating eczema and preparation method thereof
CN105381338A (en) * 2015-11-27 2016-03-09 黄德禄 Group of medicines for treating erythema multiforme

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Application publication date: 20160713