CN105748725A - Soft capsule capable of tonifying qi and blood and preparation method thereof - Google Patents

Soft capsule capable of tonifying qi and blood and preparation method thereof Download PDF

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Publication number
CN105748725A
CN105748725A CN201610192255.1A CN201610192255A CN105748725A CN 105748725 A CN105748725 A CN 105748725A CN 201610192255 A CN201610192255 A CN 201610192255A CN 105748725 A CN105748725 A CN 105748725A
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CN
China
Prior art keywords
soft capsule
invigorating
parts
radix
utricule
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Withdrawn
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CN201610192255.1A
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Chinese (zh)
Inventor
不公告发明人
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Qingdao Bairuiji Biological Engineering Co Ltd
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Qingdao Bairuiji Biological Engineering Co Ltd
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Priority to CN201610192255.1A priority Critical patent/CN105748725A/en
Publication of CN105748725A publication Critical patent/CN105748725A/en
Withdrawn legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/34—Campanulaceae (Bellflower family)
    • A61K36/344—Codonopsis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/076—Poria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236—Ligusticum (licorice-root)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284—Atractylodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A61K36/804—Rehmannia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/82—Theaceae (Tea family), e.g. camellia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A61K9/4825—Proteins, e.g. gelatin

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a soft capsule capable of tonifying qi and blood.The soft capsule comprises a capsule body and the content contained in the capsule body.The content is prepared from, by weight, 10-50 parts of radix codonopsis, 15-35 parts of rhizoma atractylodis macrocephalae, 30-80 parts of poria, 20-50 parts of radix glycyrrhizae, 15-60 parts of radix angelica sinensis, 30-70 parts of radix paeoniae alba, 20-60 parts of rhizoma chuanxiong, 10-15 parts of radix rehmanniae preparata and 5-15 parts of green tea extract.The prepared soft capsule capable of tonifying qi and blood has the advantages of being good in stability, long in shelf life and stable in character.

Description

A kind of soft capsule of invigorating qi and benefiting blood and preparation method thereof
Technical field
The present invention relates to soft capsule of a kind of invigorating qi and benefiting blood and preparation method thereof, belong to health caring product prescription technology neck Territory.
Background technology
Invigorating qi and benefiting blood, the method referring to have QI invigorating Drug therapy syndrome of deficiency of QI.Lung governing qi, main the whole body vital organs of the human body it Gas；Middle burnt taste are by Na Shuigu, and the strong fortune of temper, QI and blood is able to metaplasia, therefore the deficiency of vital energy is many with lung, the dirty phase of spleen two Close.Insufficiency of lung-QI is with deficiency of QI with disinclination to talk, and dyspnea with rapid and short breath easily, aversion to wind spontaneous perspiration is primary symptom；Deficiency of spleen-QI is with gastral cavity abdomen deficiency-distension, god Tired idle, inappetence, loose stool and diarrhea is primary symptom.Available YUPINGFENG SAN is mended and is defended gas, consolidating superficial resistance arresting sweating；With four Gentleman's soup, BUZHONG YIQI TANG invigorating middle warmer gas, help strong fortune, common drug have Radix Ginseng, the Radix Astragali, Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Rhizoma Dioscoreae, Radix Glycyrrhizae etc..
Summary of the invention
For solve the deficiencies in the prior art, it is an object of the invention to provide a kind of invigorating qi and benefiting blood soft capsule and Its preparation method.
In order to realize above-mentioned target, the present invention adopts the following technical scheme that:
The soft capsule of a kind of invigorating qi and benefiting blood, including utricule and the content being coated in utricule, described content By weight, including following component: Radix Codonopsis 10-50 part, Rhizoma Atractylodis Macrocephalae 15-35 part, Poria 30-80 part, sweet Grass 20-50 part, Radix Angelicae Sinensis 15-60 part, Radix Paeoniae Alba 30-70 part, Rhizoma Chuanxiong 20-60 part, Radix Rehmanniae Preparata 10-15 part and Green tea extract 5-15 part.
Preferably, the aforementioned Rhizoma Atractylodis Macrocephalae is Rhizoma Atractylodis Macrocephalae (parched).
The invention also discloses the preparation method of the soft capsule of foregoing a kind of invigorating qi and benefiting blood, including as follows Step: S1, by utricule high temperature sterilization, standby；
S2, prepare content: by weight, by Radix Codonopsis 10-50 part, Rhizoma Atractylodis Macrocephalae 15-35 part, Poria 30-80 Part, Radix Glycyrrhizae 20-50 part, Radix Angelicae Sinensis 15-60 part, Radix Paeoniae Alba 30-70 part, Rhizoma Chuanxiong 20-60 part, Radix Rehmanniae Preparata 10-15 Grind after part and green tea extract 5-15 part mix homogeneously and sieve, obtaining content；
The utricule of S3, the content that step S2 is obtained and S1 through pelleting, shape, wash ball, be dried, Pick ball and subpackage step, prepare the soft capsule of invigorating qi and benefiting blood.
Preferably, in abovementioned steps S1, the manufacturing process of utricule is: by weight, with gelatin 15-25 Part, stearic acid 3-6 part, soybean protein 2-3 part, glycerol 10-25 part and pure water 10-15 part are utricule raw material, Glycerol and pure water are injected in glue pot, heated and stirred, add gelatin, stearic acid and soybean protein, continue The continuous final vacuum deaeration that stirs, makes and obtains utricule.
It is highly preferred that heating-up temperature during stirring is 60-70 DEG C.
More preferably, in abovementioned steps S2, the screen cloth used that sieves is 80 mesh.
Further, in abovementioned steps S2, the preparation process of green tea extract is: be impregnated in by pulverizing green tea Percentage by volume is in the ethanol of 50%, carries out circulation extraction of heating, mistake under 60 DEG C of temperature conditionss 3 hours Filter and decompression, concentrate drying, it is thus achieved that extract.
The invention have benefit that: the soft capsule of what the present invention prepared have invigorating qi and benefiting blood has good Stability, long shelf-life, character is stable.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention made concrete introduction.
Embodiment 1
Prepare green tea extract: 200g is pulverized green tea and impregnated in the ethanol that percentage by volume is 50%, The circulation that carries out under 60 DEG C of temperature conditionss 3 hours heating extracts, and filters and reduces pressure, concentrate drying, it is thus achieved that 20g Green tea extract, standby.
Embodiment 2
Make utricule: by weight, with gelatin 15-25 part, stearic acid 3-6 part, soybean protein 2-3 part, Glycerol 10-25 part and pure water 10-15 part are utricule raw material, glycerol and pure water are injected in glue pot, and heating is stirred Mix, add gelatin, stearic acid and soybean protein, continue the final vacuum deaeration that stirs, make and obtain capsule Body, standby.
Embodiment 3
Preparation has the soft capsule of invigorating qi and benefiting blood function, and step is:
S1, the utricule high temperature sterilization that embodiment 2 is prepared, standby；
S2, prepare content: by weight, by Radix Codonopsis 10 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, 30 parts of Poria, sweet Grass 20 parts, Radix Angelicae Sinensis 15 parts, the Radix Paeoniae Alba 30 parts, Rhizoma Chuanxiong 20 parts, Radix Rehmanniae Preparata 10 parts and embodiment 1 preparation Grind after 5 parts of mix homogeneously of green tea extract and sieve, obtaining content；
The utricule of S3, the content that step S2 is obtained and S1 through pelleting, shape, wash ball, be dried, Pick ball and subpackage step, prepare the soft capsule of invigorating qi and benefiting blood.
Embodiment 4
Preparation has the soft capsule of invigorating qi and benefiting blood function, and step is:
S1, the utricule high temperature sterilization that embodiment 2 is prepared, standby；
S2, prepare content: by weight, by Radix Codonopsis 50 parts, the Rhizoma Atractylodis Macrocephalae 35 parts, 80 parts of Poria, sweet Grass 50 parts, Radix Angelicae Sinensis 60 parts, the Radix Paeoniae Alba 70 parts, Rhizoma Chuanxiong 60 parts, Radix Rehmanniae Preparata 15 parts and embodiment 1 preparation Grind after 15 parts of mix homogeneously of green tea extract and sieve, obtaining content；
The utricule of S3, the content that step S2 is obtained and S1 through pelleting, shape, wash ball, be dried, Pick ball and subpackage step, prepare the soft capsule of invigorating qi and benefiting blood.
Embodiment 5
Preparation has the soft capsule of invigorating qi and benefiting blood function, and step is:
S1, the utricule high temperature sterilization that embodiment 2 is prepared, standby；
S2, prepare content: by weight, by Radix Codonopsis 30 parts, the Rhizoma Atractylodis Macrocephalae 20 parts, 50 parts of Poria, sweet Grass 40 parts, Radix Angelicae Sinensis 30 parts, the Radix Paeoniae Alba 50 parts, Rhizoma Chuanxiong 40 parts, Radix Rehmanniae Preparata 12 parts and embodiment 1 preparation Grind after 10 parts of mix homogeneously of green tea extract and sieve, obtaining content；
The utricule of S3, the content that step S2 is obtained and S1 through pelleting, shape, wash ball, be dried, Pick ball and subpackage step, prepare the soft capsule of invigorating qi and benefiting blood.
Comparative example
Difference with embodiment 5 is: do not add green tea extract.
S1, the utricule high temperature sterilization that embodiment 2 is prepared, standby；
S2, prepare content: by weight, by Radix Codonopsis 30 parts, the Rhizoma Atractylodis Macrocephalae 20 parts, 50 parts of Poria, sweet Grind also after grass 40 parts, Radix Angelicae Sinensis 30 parts, the Radix Paeoniae Alba 50 parts, Rhizoma Chuanxiong 40 parts and 12 parts of mix homogeneously of Radix Rehmanniae Preparata Sieve, obtain content；
The utricule of S3, the content that step S2 is obtained and S1 through pelleting, shape, wash ball, be dried, Pick ball and subpackage step, prepare the soft capsule of invigorating qi and benefiting blood.
Being detected by the product that the various embodiments described above and comparative example obtain, result is as follows:
Place 24 months for 25 DEG C
Embodiment 3 Unchanged
Embodiment 4 Unchanged
Embodiment 5 Unchanged
Comparative example Rotten
To sum up, the prescription of invigorating qi and benefiting blood is made soft capsule by the present invention, is convenient for carrying and takes, nontoxic secondary work With, and with the addition of green tea extract and can preferably improve the stability of content, prevent from going bad, it is possible to Extend the shelf life.
The ultimate principle of the present invention, principal character and advantage have more than been shown and described.The technology people of the industry Member is it should be appreciated that above-described embodiment limits the present invention, all employing equivalents or equivalence change the most in any form The technical scheme that the mode changed is obtained, all falls within protection scope of the present invention.

Claims (7)

1. the soft capsule of an invigorating qi and benefiting blood, it is characterized in that, including utricule and the content being coated in utricule, described content by weight, including following component: Radix Codonopsis 10-50 part, Rhizoma Atractylodis Macrocephalae 15-35 part, Poria 30-80 part, Radix Glycyrrhizae 20-50 part, Radix Angelicae Sinensis 15-60 part, Radix Paeoniae Alba 30-70 part, Rhizoma Chuanxiong 20-60 part, Radix Rehmanniae Preparata 10-15 part and green tea extract 5-15 part.
The soft capsule of a kind of invigorating qi and benefiting blood the most according to claim 1, it is characterised in that the described Rhizoma Atractylodis Macrocephalae is Rhizoma Atractylodis Macrocephalae (parched).
The preparation method of the soft capsule of a kind of invigorating qi and benefiting blood the most as claimed in claim 1, it is characterised in that comprise the steps:
S1, by utricule high temperature sterilization, standby；
S2, prepare content: by weight, by grinding after Radix Codonopsis 10-50 part, Rhizoma Atractylodis Macrocephalae 15-35 part, Poria 30-80 part, Radix Glycyrrhizae 20-50 part, Radix Angelicae Sinensis 15-60 part, Radix Paeoniae Alba 30-70 part, Rhizoma Chuanxiong 20-60 part, Radix Rehmanniae Preparata 10-15 part and green tea extract 5-15 part mix homogeneously and sieving, obtain content；
The utricule of S3, the content that step S2 is obtained and S1 through pelleting, shape, wash ball, be dried, pick ball and subpackage step, prepare the soft capsule of invigorating qi and benefiting blood.
The preparation method of the soft capsule of a kind of invigorating qi and benefiting blood the most according to claim 3, it is characterized in that, in described step S1, the manufacturing process of utricule is: by weight, with gelatin 15-25 part, stearic acid 3-6 part, soybean protein 2-3 part, glycerol 10-25 part and pure water 10-15 part for utricule raw material, injects in glue pot by glycerol and pure water, heated and stirred, add gelatin, stearic acid and soybean protein, continue the final vacuum deaeration that stirs, make and obtain utricule.
The preparation method of the soft capsule of a kind of invigorating qi and benefiting blood the most according to claim 4, it is characterised in that heating-up temperature during stirring is 60-70 DEG C.
The preparation method of the soft capsule of a kind of invigorating qi and benefiting blood the most according to claim 3, it is characterised in that in described step S2, the screen cloth used that sieves is 80 mesh.
The preparation method of the soft capsule of a kind of invigorating qi and benefiting blood the most according to claim 3, it is characterized in that, in described step S2, the preparation process of green tea extract is: impregnated in the ethanol that percentage by volume is 50% by pulverizing green tea, circulation extraction of heating is carried out 3 hours under 60 DEG C of temperature conditionss, filter and decompression, concentrate drying, it is thus achieved that extract.
CN201610192255.1A 2016-03-30 2016-03-30 Soft capsule capable of tonifying qi and blood and preparation method thereof Withdrawn CN105748725A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610192255.1A CN105748725A (en) 2016-03-30 2016-03-30 Soft capsule capable of tonifying qi and blood and preparation method thereof

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Application Number Priority Date Filing Date Title
CN201610192255.1A CN105748725A (en) 2016-03-30 2016-03-30 Soft capsule capable of tonifying qi and blood and preparation method thereof

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105031005A (en) * 2015-06-25 2015-11-11 北京康远制药有限公司 Micro pills capable of tonifying qi and benefiting blood
CN105079044A (en) * 2015-09-23 2015-11-25 李�杰 Preparation method of soft capsules containing Chinese caterpillar funguses

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105031005A (en) * 2015-06-25 2015-11-11 北京康远制药有限公司 Micro pills capable of tonifying qi and benefiting blood
CN105079044A (en) * 2015-09-23 2015-11-25 李�杰 Preparation method of soft capsules containing Chinese caterpillar funguses

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Application publication date: 20160713