CN105748383A - Royal jelly extract-containing anti-aging skin cream and preparation method thereof - Google Patents

Royal jelly extract-containing anti-aging skin cream and preparation method thereof Download PDF

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Publication number
CN105748383A
CN105748383A CN201610080758.XA CN201610080758A CN105748383A CN 105748383 A CN105748383 A CN 105748383A CN 201610080758 A CN201610080758 A CN 201610080758A CN 105748383 A CN105748383 A CN 105748383A
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CN
China
Prior art keywords
lac regis
regis apis
skin cream
aging skin
skin
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610080758.XA
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Chinese (zh)
Inventor
郭雷平
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kingway Cosmetics Technology Guangzhou Co Ltd
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Kingway Cosmetics Technology Guangzhou Co Ltd
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Filing date
Publication date
Application filed by Kingway Cosmetics Technology Guangzhou Co Ltd filed Critical Kingway Cosmetics Technology Guangzhou Co Ltd
Priority to CN201610080758.XA priority Critical patent/CN105748383A/en
Publication of CN105748383A publication Critical patent/CN105748383A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • A61K8/988Honey; Royal jelly, Propolis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0295Liquid crystals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • A61K8/375Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses royal jelly extract-containing anti-aging skin cream and a preparation method thereof. The anti-aging skin cream is prepared from the following raw material components by weight percent: 1-10% of royal jelly extract, 1-5% of an emulsifying agent, 0.1-0.5% of a thickening agent, 0.1-1% of other active additives, 0.1-0.5% of a preservative, 5-15% of grease and the balance of deionized water. The anti-aging skin cream provided by the invention utilizes a combination of the royal jelly, oat beta-glucan, cetearyl olivate and sorbitan olivate, thus having functions of delaying facial skin aging and maintaining the skin to be moisturized, soft and smooth.

Description

A kind of anti-aging skin cream containing Lac regis apis extract and preparation method thereof
Technical field
The present invention relates to a kind of cosmetics, belong to daily technical field of skin care, particularly relate to a kind of containing Lac regis apis extraction The preparation method of the anti-aging skin cream of thing.
Background technology
Women expects that skin of face slow down aging, Lac regis apis extract contain abundant proline, aspartic acid, vitamin B race material and vitamin C, proline and aspartic acid can promote the synthesis of collagen protein and elastin laminin, vitamin B9 (folic acid) promotes new city metabolism and the tissue regeneration of cell, and vitamin B, vitamin C have good antioxidant activity to keep away Exempt from the injury of radical pair skin, have some to add the cosmetics of Lac regis apis extract the most on the market, but skin absorption is sharp The highest by rate, compare the most difficult playing a role.
Summary of the invention
It is an object of the invention to provide a kind of anti-aging skin cream containing Lac regis apis extract, thus delay skin of face to decline Always, skin is made to continue water profit soft and smooth.
It is a further object of the present invention to provide the preparation method of a kind of above-mentioned anti-aging skin cream containing Lac regis apis extract.
In order to realize the above-mentioned purpose of the present invention, the invention provides following technical scheme:
A kind of anti-aging skin cream containing Lac regis apis extract, by weight percentage, comprises following raw material components:
Lac regis apis extract 1-10%;Emulsifying agent 1-5%;Thickening agent 0.1-0.5%;Other active additives 0.1-1%; Preservative 0.1-0.5%;Oils and fats 5-15%;Surplus is deionized water.
The present invention containing the anti-aging skin cream of Lac regis apis extract, described emulsifying agent select cetearyl alcohol olive oil acid esters and Pyrusussuriensis smooth olive oil acid esters is main, is auxiliary with PEG-100 glyceryl stearate.
The present invention anti-aging skin cream containing Lac regis apis extract, described thickening agent is carbomer.
The present invention anti-aging skin cream containing Lac regis apis extract, other active additives described are tocopherol acetas, swallow Wheat beta glucan.
The present invention anti-aging skin cream containing Lac regis apis extract, described preservative is methyl hydroxybenzoate, propyl hydroxybenzoate, methyl Three kinds or four kinds combinations in isothiazolone and Sensiva SC50, double hydroxy methylimidazole ureine.
The present invention anti-aging skin cream containing Lac regis apis extract, described oils and fats is dicaprylyl carbonate, isopropyl palmitate etc. Skin protection oils and fats.
The preparation method of the above-mentioned anti-aging skin cream containing Lac regis apis extract, comprises the following steps:
1) each component is weighed according to formula;
2) by water, butanediol, glycerol, methyl hydroxybenzoate, carbomer, addition aqueous phase pot, stirring is warmed up to 75 to 85 DEG C, insulated and stirred 20 to 30 minutes;
3) by cetearyl alcohol, dicaprylyl carbonate, cetearyl alcohol olive oil acid esters, Pyrusussuriensis smooth olive oil acid esters, PEG-100 glyceryl stearate, isopropyl palmitate, tocopherol acetas add emulsifying pot and are warmed up to 75 to 85 DEG C, Stop aqueous phase suction under stirring, exhaust rear insulated and stirred 20 to 30 minutes, triethanolamine is added, start stirring fall Temperature;
4) cool to 45 DEG C by avenabeta glucosan, Lac regis apis extract, Methylisothiazolinone and Sensiva SC50, Essence adds stirring 30 minutes, checks qualified discharging.
By technique scheme, there is advantages that
1) utilize the reasonably combined recipe ingredient of the two emulsifying agent, then by after oil mixing with water without homogenization, and adopt By 80 DEG C of high-speed stirred to cooling to the special process of 38 DEG C, it is deployed into the layered liquid crystal of simulated skin cell grease structure The cream of structure, opens skin barrier, promotes that active matter penetrates into skin.
2) Lac regis apis extract, avenabeta glucosan, cetearyl alcohol olive oil acid esters, Pyrusussuriensis smooth Fructus Canarii albi oleic acid are utilized Ester combines, and develops a kind of anti-aging skin cream containing Lac regis apis extract, thus delays skin of face old and feeble, makes skin hold Continuous water profit is soft and smooth.
Accompanying drawing explanation
Fig. 1 is the face change in friction force rate signal after the present invention uses the anti-aging skin cream containing Lac regis apis extract Figure.
Detailed description of the invention
The anti-aging skin cream containing Lac regis apis extract of the present invention, comprises following primary raw material component:
Lac regis apis extract (PROVITAL company of Spain): Lac regis apis is the food of nurture children honeybee, and queen bee is lifelong Unique food, be Worker head body of gland produce, be mixed with pollen, Mel, water, the saliva of Apis, hormone and Wei Sheng Element.Containing including proline and aspartic acid 17 kinds, with vitamin A, vitamin D, vitamin B1, B2, B5, B6, B9, B12 race material, vitamin C, proline and aspartic acid can promote collagen protein and elastin laminin Synthesis, FA (folic acid) promotes the new city metabolism of cell and tissue regeneration, and vitamin B, vitamin C have well Antioxidant activity avoid the injury of radical pair skin.
Avenabeta glucosan (the fragrant company of Germany's moral produces) can improve resisting skin allergy ability, activates immunologic function, Delay skin aging.
Cetearyl alcohol olive oil acid esters, Pyrusussuriensis smooth olive oil acid esters (production of HALLSTAR company of the U.S.), Fructus Canarii albi Source Organic certification emulsifying agent, utilizes the reasonably combined recipe ingredient of the two emulsifying agent, then by need not be equal after oil mixing with water Matter technique, and use 80 DEG C of high-speed stirred to cooling to the special process of 38 DEG C, it is deployed into simulated skin cell grease knot The cream of the layered liquid crystal structure of structure, opens skin barrier, promotes that active matter penetrates into skin.
Present invention aim at working out the liquid crystal type cream that a promotion Lac regis apis absorbs, Lac regis apis is Worker head body of gland Produce, be mixed with pollen, Mel, water, the saliva of Apis, hormone and vitamin.Containing abundant proline and Radix Asparagi Propylhomoserin and vitamin B complex material, vitamin C, proline and aspartic acid can promote collagen protein and elastin laminin Synthesis, FA (folic acid) promotes new city metabolism and the tissue regeneration of cell, and vitamin B, vitamin C have good Antioxidant activity avoids the injury of radical pair skin, and the present invention is to utilize Pyrusussuriensis smooth olive oil acid esters and cetearyl alcohol olive This two emulsifying agent of olive oleate forms the slim and graceful beautiful liquid crystal type emulsified body cream of a outward appearance by special technique again, increases Strong skin physiology infiltration, promotes the skin absorption to royal jelly activity thing, the maximum anti-ageing merit playing royal jelly activity thing Effect.
Combine effect test example content description of the invention book below by way of concrete preferred embodiment to make the most specifically Bright, but the present invention is not limited in below example.
Embodiment 1-3
The present invention defying age skin containing Lac regis apis extract its formula white and content, as shown in table 1 below.
Defying age skin frost (weight percentage: %) of table 1 embodiment 1-3
The anti-aging skin cream production process (operating process) containing Lac regis apis extract of above-described embodiment 1-3, can It is expressed as follows:
1) by water, butanediol, glycerol, methyl hydroxybenzoate, carbomer, addition aqueous phase pot, stirring is warmed up to 80 DEG C, protects Temperature stirring 20 minutes;
2) by cetearyl alcohol, dicaprylyl carbonate, cetearyl alcohol olive oil acid esters, Pyrusussuriensis smooth olive oil acid esters (or Person's PEG-100 glyceryl stearate), isopropyl palmitate, tocopherol acetas;
3) add emulsifying pot and be warmed up to 80 DEG C, stop aqueous phase suction under stirring stirring, stir 20 minutes after exhausting, will Triethanolamine adds, and starts stirring cooling;
4) cool to 45 DEG C by avenabeta glucosan, Lac regis apis extract, Methylisothiazolinone and Sensiva SC50, Essence adds stirring 30 minutes.
5) qualified discharging fill is checked.
Effect test example
Skin smoothness is to embody one of skin aging index, and we utilize Germany's CK (MPA 9) skinanalysis apparatus test The rate of change of skin friction this index of power observes the change of skin health, has looked for 15 women of about 40 years old, Being divided into 3 groups, often organize 5 people, often group is respectively adopted moisturiser Ge Tu face sooner or later that embodiment 1-3 formula makes once, Respectively the 0th day, the 7th day, the 14th day, the 21st day, the 28th day with Germany CK (MPA 9) skinanalysis apparatus Test face skin friction power, test result is as shown in table 2 below:
Table 2 skin smoothness test aging index
Face's change in friction force rate see table shown in 3.
Table 3 face change in friction force rate
7th day 14th day 21st day 28th day
First group -5.13% -11.18% -18.43% -23.88%
Second group -3.09% -6.27% -9.12% -12.79%
3rd group -1.69% -3.07% -4.17% -4.92%
By the content of Fig. 1 and Biao 2,3, by observing, volunteer uses three sections of protective skin cream, skin friction power after 28 days Having reduction, wherein scribble the protective skin cream that embodiment 1 produces, skin friction power rate of change is maximum, and it is obvious that skin improves mouth, Scribbling the protective skin cream that embodiment 2 formula produces, skin friction power rate of change is the half of the protective skin cream using embodiment 1 Left and right, and use embodiment 3 formula to produce protective skin cream, skin improves inconspicuous, illustrates that Lac regis apis embodiment 1 formula is raw The protective skin cream produced has the effect preferably improving skin aging, with cetearyl alcohol olive oil acid esters, Pyrusussuriensis smooth olive oil acid esters Doing the liquid crystal type cream that emulsifying agent is fabricated to and contribute to skin absorption Lac regis apis extract, maximum its defying age of performance is made With.
Experiment conclusion: add Lac regis apis, avenabeta glucosan, cetearyl alcohol olive oil acid esters, Pyrusussuriensis smooth Fructus Canarii albi oleic acid The protective skin cream of ester has good smooth out wrinkles and delays skin of face old and feeble, makes skin continue water profit soft and smooth.
The above, be only presently preferred embodiments of the present invention, and the present invention not makees any pro forma restriction, therefore Every without departing from technical solution of the present invention content, according to the technical spirit of the present invention above example is made any simply Amendment, equivalent variations and modification, all still fall within the range of technical solution of the present invention.

Claims (7)

1. the anti-aging skin cream containing Lac regis apis extract, it is characterised in that by weight percentage, comprise as Lower raw material components:
Lac regis apis extract 1-10%;
Emulsifying agent 1-5%;
Thickening agent 0.1-0.5%;
Other active additives 0.1-1%;
Preservative 0.1-0.5%;
Oils and fats 5-15%;
Surplus is deionized water.
Anti-aging skin cream containing Lac regis apis extract the most according to claim 1, it is characterised in that: described breast Agent selects cetearyl alcohol olive oil acid esters and Pyrusussuriensis smooth olive oil acid esters to be main, with PEG-100 glyceryl stearate It is auxiliary.
Anti-aging skin cream containing Lac regis apis extract the most according to claim 1, it is characterised in that: described increasing Thick dose is carbomer.
Anti-aging skin cream containing Lac regis apis extract the most according to claim 1, it is characterised in that: described its His active additive is tocopherol acetas, avenabeta glucosan.
Anti-aging skin cream containing Lac regis apis extract the most according to claim 1, it is characterised in that: described anti- Rotten agent is in methyl hydroxybenzoate, propyl hydroxybenzoate, Methylisothiazolinone and Sensiva SC50, double hydroxy methylimidazole ureine Three kinds or four kinds combinations.
Anti-aging skin cream containing Lac regis apis extract the most according to claim 1, it is characterised in that: described oil Fat is the skin protection oils and fats such as dicaprylyl carbonate, isopropyl palmitate.
7. the preparation side of the anti-aging skin cream containing Lac regis apis extract as according to any one of claim 1-6 Method, it is characterised in that comprise the following steps:
1) each component is weighed according to formula;
2) by water, butanediol, glycerol, methyl hydroxybenzoate, carbomer, addition aqueous phase pot, stirring is warmed up to 75 to 85 DEG C, insulated and stirred 20 to 30 minutes;
3) by cetearyl alcohol, dicaprylyl carbonate, cetearyl alcohol olive oil acid esters, Pyrusussuriensis smooth olive oil acid esters, PEG-100 glyceryl stearate, isopropyl palmitate, tocopherol acetas add emulsifying pot and are warmed up to 75 to 85 DEG C, Stop aqueous phase suction under stirring stirring, exhaust rear insulated and stirred 20 to 30 minutes, triethanolamine is added, starts to stir Mix cooling;
4) cool to 45 DEG C by avenabeta glucosan, Lac regis apis extract, Methylisothiazolinone and Sensiva SC50, Essence adds stirring 30 minutes, checks qualified discharging.
CN201610080758.XA 2016-02-04 2016-02-04 Royal jelly extract-containing anti-aging skin cream and preparation method thereof Pending CN105748383A (en)

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Application Number Priority Date Filing Date Title
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Application Number Priority Date Filing Date Title
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108653141A (en) * 2018-06-28 2018-10-16 广西浙缘农业科技有限公司 A kind of oil tea face cream and preparation method thereof
CN113143837A (en) * 2021-02-07 2021-07-23 深圳市琉璃光生物科技有限公司 Anti-aging skin-tendering composition and preparation method thereof
CN114099364A (en) * 2021-12-09 2022-03-01 北京中蜜科技发展有限公司 Emulsion containing royal jelly enzymolysis polypeptide and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102366390A (en) * 2011-11-14 2012-03-07 哈药集团三精制药股份有限公司 Ginseng royal-jelly cosmetic
CN104958247A (en) * 2015-06-30 2015-10-07 湖南炎帝生物工程有限公司 Body lotion containing Nostoc sphaeroids extract and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102366390A (en) * 2011-11-14 2012-03-07 哈药集团三精制药股份有限公司 Ginseng royal-jelly cosmetic
CN104958247A (en) * 2015-06-30 2015-10-07 湖南炎帝生物工程有限公司 Body lotion containing Nostoc sphaeroids extract and preparation method thereof

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108653141A (en) * 2018-06-28 2018-10-16 广西浙缘农业科技有限公司 A kind of oil tea face cream and preparation method thereof
CN113143837A (en) * 2021-02-07 2021-07-23 深圳市琉璃光生物科技有限公司 Anti-aging skin-tendering composition and preparation method thereof
CN114099364A (en) * 2021-12-09 2022-03-01 北京中蜜科技发展有限公司 Emulsion containing royal jelly enzymolysis polypeptide and preparation method thereof
CN114099364B (en) * 2021-12-09 2023-11-10 北京中蜜科技发展有限公司 Emulsion containing royal jelly enzymolysis polypeptide and preparation method thereof

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Application publication date: 20160713