CN105727138A - Traditional Chinese medicinal composition for treating fatty liver due to liver depression and spleen deficiency and preparation method thereof - Google Patents
Traditional Chinese medicinal composition for treating fatty liver due to liver depression and spleen deficiency and preparation method thereof Download PDFInfo
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- A61K36/88—Liliopsida (monocotyledons)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/26—Aristolochiaceae (Birthwort family), e.g. heartleaf
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- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
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Abstract
The invention belongs to the technical field of traditional Chinese medicines and aims at providing a traditional Chinese medicinal composition for treating fatty liver due to liver depression and spleen deficiency according to knowledge mechanism of traditional Chinese medicine on the fatty liver due to liver depression and spleen deficiency. The traditional Chinese medicinal composition comprises the following components by mass: 2.5-6g of yangchun amomum flower, 9-16g of fiveleaf akebia fruit, 2.5-5g of tangerine pith, 4.5-9g of szechwan chinaberry fruit, 15-30g of platycarya strobilacea fruit, 10-38g of dutchmanspipe root, 3-6g of rhizoma nardostachyos, 3-10g of elecampane inula root, 10-15g of bauhinia lecomtei gagn, 210-320g of acanthus ilicifolius, 3-10g of ovate tylophora root and rhizome, 9-15g of lemon leaves and 10-15g of root of tall lettuce. The traditional Chinese medicinal composition for treating the fatty liver due to the liver depression and spleen deficiency has the characteristics of good pharmaceutical effect, quick effect and low cost.
Description
Technical field
The present invention relates to technical field of Chinese medicine, be specifically related to a kind of Chinese medicine composition treating liver-depression spleen-insufficiency type fatty liver, especially for the field of the Chinese medicine composition that liver-depression spleen-insufficiency type fatty liver patient uses and preparation method thereof.
Background technology
Stagnation of liver-QI with deficiency of the spleen, refers to the liver failing to maintain the normal flow of QI, dysfunction of the spleen in transportation and show the syndrome being primary symptom with distending pain in the chest and hypochondrium, abdominal distention, loose stool etc..Demonstrate,prove also known as incoordination between the liver and spleen.Liver controlling conveyance and dispersion, depression of liver-QI then catharsis is unfavorable, temper also therefore transformation failure of spleen, the syndrome based on digestive function weakness occurs, and as lack of appetite is indigestion and loss of appetite, gastral cavity abdominal distention is vexed, extremity asthenia, borborygmus flatus, and coerces distending pain etc..
Fatty liver condition is a kind of common clinical picture, but not a kind of independent disease.The lighter is asymptomatic in its clinical manifestation, and the severe one state of an illness is violent.It is said that in general, fatty liver belongs to reversibility disease, early diagnosis is also treated in time and often can be recovered normal.In the liver of normal person, total fat mass, accounts for the 5% of liver weight, includes phospholipid, triglyceride, fat acid, cholesterol and cholesterol ester.Fat mass is mild fatty liver more than 5%, is moderate fatty liver more than 10%, is severe fatty liver more than 25%.When fat mass total in liver is more than 30%, could check out with B ultrasonic, be diagnosed as " fatty liver " by ultrasound diagnosis.And Patients with Fatty Liver, total fat amount is up to 40%-50%, and some reaches more than 60%, mainly triglyceride and fat acid, and the only a small amount of increase of phospholipid, cholesterol and cholesterol ester.
So, just how to find a kind of Chinese medicine composition that can effectively treat above-mentioned liver-depression spleen-insufficiency type fatty liver, be our current problem in urgent need to solve.
Summary of the invention
Development along with China's Chinese medicine, on treatment liver-depression spleen-insufficiency type fatty liver, the advantage that people appreciate the above-mentioned liver-depression spleen-insufficiency type fatty liver of Chinese traditional treatment gradually, and the advantage such as toxic and side effects is little over the course for the treatment of, expense is low, present situation for the above-mentioned liver-depression spleen-insufficiency type fatty liver of existing western medical treatment, it is an object of the invention to be in that to provide a kind of Chinese medicine composition treating liver-depression spleen-insufficiency type fatty liver, to solve liver-depression spleen-insufficiency type fatty liver patient restorative problem early.This medicine is with common Chinese medicine for raw material, has instant effect, the feature such as evident in efficacy, and can effectively treat above-mentioned liver-depression spleen-insufficiency type fatty liver.
For reaching the purpose of foregoing invention, the technical solution adopted in the present invention is: provide a kind of Chinese medicine composition treating liver-depression spleen-insufficiency type fatty liver and preparation method thereof, it is characterised in that each component and the mass parts ratio thereof of described Chinese medicine composition are as follows:
Flos Amomi villosi 2.5～6g, Fructus Akebiae 9～16g, Vascular aurantii 2.5～5g, Fructus Toosendan 4.5～9g, Fructus Platycaryae strobilaceac 15～30g, Radix Aristolochiae 10～38g, Radix Et Rhizoma Nardostachyos 3～6g, Radix Inulae 3～10g, Radix Bauhiniae Lecomtei 10～15g, mouse 210～320g, Radix Et Rhizoma Tylophorae Ovatae 3～10g, Folium Citri Limoniae 9～15g, Radix Lactucae elatae 10～15g.
A kind of Chinese medicine composition treating liver-depression spleen-insufficiency type fatty liver and preparation method thereof, it is characterised in that each component and the mass parts ratio thereof of described Chinese medicine composition are as follows:
Flos Amomi villosi 3.5～5.5g, Fructus Akebiae 10～14g, Vascular aurantii 3.5～4.5g, Fructus Toosendan 6～8g, Fructus Platycaryae strobilaceac 20～26g, Radix Aristolochiae 20～36g, Radix Et Rhizoma Nardostachyos 3.5～5.5g, Radix Inulae 6～9g, Radix Bauhiniae Lecomtei 11～13g, mouse 250～280g, Radix Et Rhizoma Tylophorae Ovatae 6～9g, Folium Citri Limoniae 10～13g, Radix Lactucae elatae 11～14g.
A kind of Chinese medicine composition treating liver-depression spleen-insufficiency type fatty liver and preparation method thereof, it is characterised in that each component and the mass parts ratio thereof of the Chinese medicine composition of described " preferred plan " are as follows:
Flos Amomi villosi 5g, Fructus Akebiae 13g, Vascular aurantii 4g, Fructus Toosendan 7g, Fructus Platycaryae strobilaceac 23g, Radix Aristolochiae 32g, Radix Et Rhizoma Nardostachyos 5g, Radix Inulae 8g, Radix Bauhiniae Lecomtei 12g, mouse 255g, Radix Et Rhizoma Tylophorae Ovatae 8g, Folium Citri Limoniae 12g, Radix Lactucae elatae 13g.
A kind of Chinese medicine composition treating liver-depression spleen-insufficiency type fatty liver and preparation method thereof, it is characterised in that described method comprises the steps to be prepared from:
A, above-mentioned raw materials Chinese medicine is picked decontamination and dust after, be respectively crushed into coarse according to mass parts ratio and decoct a drug wrapped；
B, the raw material Chinese medicine wrapped is put in cold boiled water immersion half an hour, then again the clear liquor of soaked medicine and soak medicine is put into marmite in the lump, the cold boiled water injecting medicine 38mm carries out first time decoction 45 minutes, after leaching medicinal liquid, the tepor boiled water re-injecting medicine 35mm carries out second time decoction 35 minutes, and the herb liquid 540 milliliters that secondary mixing is condensed into 50% is standby.
A kind of Chinese medicine composition treating liver-depression spleen-insufficiency type fatty liver and preparation method thereof, it is characterised in that described instructions of taking is: being taken with one day by the herb liquid prepared, the morning, noon and afternoon service once, dosage 180 milliliter/time, taking medicine before meal.Taking medicine 15～45 days, transference cure, disease obtains recovery from illness.
Each raw material Chinese medicine in prescription of the present invention is all documented in detail in Chinese Pharmacopoeia, China's dictionary and China's book on Chinese herbal medicine.The present invention selects most common of which Chinese medicine to be raw material, gives full play to the pharmacological effect of each component:
Flos Amomi villosi, nature and flavor: pungent, flat, nontoxic, there is the fast diaphragm of sharp lung, stomach function regulating in tune；
Fructus Akebiae, nature and flavor: hide micro-hardship, property is put down, there is effect of dispersing the stagnated liver-QI for regulating the stomach, promoting blood circulation and stopping pain, hard masses softening and resolving, diuresis, be used for treating stagnation of liver-QI and stomach-QI, the disease such as gastral cavity abdomen, the side of body help distending pain, diet not to disappear, dysentery is just let out, hernia pain, lumbago, amenorrhea dysmenorrhea, goiter scrofula, malignant tumor；
Vascular aurantii, nature and flavor: sweet, bitter, flat, there is dredging collateral, regulate the flow of vital energy, clears phlegm, be used for treating blockage of meridian-QI, chronic cough chest pain, sputum mixed with blood, get sick from drinking too much wine thirsty；
Fructus Toosendan, nature and flavor: bitter, cold, slightly poisonous, there is effect of soothing liver-QI promoting the circulation of QI to relieve pain, anthelmintic, be used for treating the breast side of body, abdominal distention, colic, abdominal pain due to worm stagnation；
Fructus Platycaryae strobilaceac, nature and flavor: pungent, warm, there is effect of regulating qi and dispelling wind, reducing swelling and alleviating pain, removing dampness and killing parasites, be used for treating the diseases such as internal injury breast swollen, stomachache, bones and muscles pain, carbuncle, eczema, scabies；
Radix Aristolochiae, nature and flavor: bitter, tepor, there is effect of circulation of qi promoting stomach invigorating, pain relieving, be used for treating stomachache, traumatic injury；
Radix Et Rhizoma Nardostachyos, nature and flavor: acrid in the mouth, sweet, warm in nature, there is effect of regulating QI to relieve pain, activating spleen and strengthening stomach, be used for treating abdominal distention, not national diet, toothache, beriberi；
Radix Inulae, nature and flavor: acrid, bitter, warm, there is effect that invigorating the spleen and regulating the stomach, promoting the flow of QI for relieving the stagnancy, pain relieving are antiabortive, be used for treating the breast side of body, abdominal distention, vomiting dysentery, the breast side of body are dampened, feel a pain in the chest when breathing have a pain, frequent fetal movement；
Radix Bauhiniae Lecomtei, nature and flavor: hardship sweet, micro-, temperature, there is effect of regulating QI to relieve pain, diuresis blood stasis dispelling, be used for treating dysuria, impairment caused by overstrain lumbago, retention of placenta, traumatic injury；
Mouse, nature and flavor: bitter, cool, have protect the liver, effect of function of gallbladder promoting, be used for treating acute hepatitis, chronic hepatitis；
Radix Et Rhizoma Tylophorae Ovatae, nature and flavor: pungent, warm, slightly poisonous, have dispel wind and remove dampness, eliminating stasis to stop pain, relieving cough and relieving asthma, removing toxic substances effect, be used for treating rheumatic ostalgia, cough, asthma, treating swelling and pain by traumatic injury, venom；
Folium Citri Limoniae, nature and flavor: hardship pungent, sweet, micro-, tepor, there is effect of preventing phlegm from forming and stopping coughing, regulating qi-flowing for harmonizing stomach, antidiarrheal, be used for diseases such as treating cough with asthma abundant expectoration, stagnation of QI abdominal distention, have loose bowels；
Radix Lactucae elatae, nature and flavor: pungent, flat, the effect there is relieving cough and resolving phlegm, dispeling the wind, it is used for treating cough due to wind and cold, pulmonary tuberculosis.
Medicine of the present invention is based on the differential diagnosis of diseases of Chinese traditional treatment liver-depression spleen-insufficiency type fatty liver and the dialectical principle combined, think from pharmacological action and mechanism of action: liver-depression spleen-insufficiency type fatty liver one is demonstrate,proved, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, and above-mentioned disease is had good therapeutic effect.
Detailed description of the invention
The present invention is aiming at the treatment of above-mentioned liver-depression spleen-insufficiency type fatty liver and a kind of Chinese medicine formula of proposing, adopts medicine effect prepared by this formula good, and instant effect, is the Chinese prescription of a treating both the principal and secondary aspects of a disease, is particularly suitable for Clinical practice.It is described in further detail below in conjunction with the specific embodiment of the present invention:
Embodiment 1:
A kind of Chinese medicine composition treating liver-depression spleen-insufficiency type fatty liver, it is characterised in that each component of described Chinese medicine composition and mass parts ratio are as follows:
Flos Amomi villosi 5g, Fructus Akebiae 13g, Vascular aurantii 4g, Fructus Toosendan 7g, Fructus Platycaryae strobilaceac 23g, Radix Aristolochiae 32g, Radix Et Rhizoma Nardostachyos 5g, Radix Inulae 8g, Radix Bauhiniae Lecomtei 12g, mouse 255g, Radix Et Rhizoma Tylophorae Ovatae 8g, Folium Citri Limoniae 12g, Radix Lactucae elatae 13g.
Embodiment 2:
A kind of Chinese medicine composition treating liver-depression spleen-insufficiency type fatty liver, it is characterised in that each component of described Chinese medicine composition and mass parts ratio are as follows:
Flos Amomi villosi 5.5g, Fructus Akebiae 14g, Vascular aurantii 4.5g, Fructus Toosendan 8g, Fructus Platycaryae strobilaceac 26g, Radix Aristolochiae 36g, Radix Et Rhizoma Nardostachyos 5.5g, Radix Inulae 9g, Radix Bauhiniae Lecomtei 13g, mouse 280g, Radix Et Rhizoma Tylophorae Ovatae 9g, Folium Citri Limoniae 13g, Radix Lactucae elatae 14g.
Embodiment 3:
A kind of Chinese medicine composition treating liver-depression spleen-insufficiency type fatty liver, it is characterised in that each component of described Chinese medicine composition and mass parts ratio are as follows:
Flos Amomi villosi 6g, Fructus Akebiae 16g, Vascular aurantii 5g, Fructus Toosendan 9g, Fructus Platycaryae strobilaceac 30g, Radix Aristolochiae 38g, Radix Et Rhizoma Nardostachyos 6g, Radix Inulae 10g, Radix Bauhiniae Lecomtei 15g, mouse 320g, Radix Et Rhizoma Tylophorae Ovatae 10g, Folium Citri Limoniae 15g, Radix Lactucae elatae 15g.
Model case:
Through clinical conditions liver-depression spleen-insufficiency type fatty liver patient totally 132 example, the age is 90 examples of more than 48 years old, and only 42 examples are less than 48 years old.102 examples of recovery from illness in 132 example patients, 30 effective examples, total effective rate reaches 100%.After treatment, disease obtains recovery from illness.
Claims (3)
1. the Chinese medicine composition treating liver-depression spleen-insufficiency type fatty liver, it is characterised in that each component of described Chinese medicine composition and mass parts ratio thereof are as follows:
Flos Amomi villosi 2.5～6g, Fructus Akebiae 9～16g, Vascular aurantii 2.5～5g, Fructus Toosendan 4.5～9g, Fructus Platycaryae strobilaceac 15～30g, Radix Aristolochiae 10～38g, Radix Et Rhizoma Nardostachyos 3～6g, Radix Inulae 3～10g, Radix Bauhiniae Lecomtei 10～15g, mouse 210～320g, Radix Et Rhizoma Tylophorae Ovatae 3～10g, Folium Citri Limoniae 9～15g, Radix Lactucae elatae 10～15g.
2. the Chinese medicine composition for the treatment of liver-depression spleen-insufficiency type fatty liver according to claim 1, it is characterised in that each component of described Chinese medicine composition and mass parts ratio thereof are as follows:
Flos Amomi villosi 3.5～5.5g, Fructus Akebiae 10～14g, Vascular aurantii 3.5～4.5g, Fructus Toosendan 6～8g, Fructus Platycaryae strobilaceac 20～26g, Radix Aristolochiae 20～36g, Radix Et Rhizoma Nardostachyos 3.5～5.5g, Radix Inulae 6～9g, Radix Bauhiniae Lecomtei 11～13g, mouse 250～280g, Radix Et Rhizoma Tylophorae Ovatae 6～9g, Folium Citri Limoniae 10～13g, Radix Lactucae elatae 11～14g.
3. the Chinese medicine composition of the treatment liver-depression spleen-insufficiency type fatty liver according to claim 1 to 2, it is characterised in that each component of described Chinese medicine composition and mass parts ratio thereof are as follows:
Flos Amomi villosi 5g, Fructus Akebiae 13g, Vascular aurantii 4g, Fructus Toosendan 7g, Fructus Platycaryae strobilaceac 23g, Radix Aristolochiae 32g, Radix Et Rhizoma Nardostachyos 5g, Radix Inulae 8g, Radix Bauhiniae Lecomtei 12g, mouse 255g, Radix Et Rhizoma Tylophorae Ovatae 8g, Folium Citri Limoniae 12g, Radix Lactucae elatae 13g.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103638441A (en) * | 2013-12-15 | 2014-03-19 | 杜纪昌 | Traditional Chinese medicinal composition for treating fatty liver with liver stagnation and spleen deficiency symptom |
| EP2891496A1 (en) * | 2012-08-28 | 2015-07-08 | Neumed | Pharmaceutical composition containing complex extract of aurantii nobilis pericarpium and crataegus as an active ingredient for treating or preventing obesity or lipid-related metabolic diseases |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2891496A1 (en) * | 2012-08-28 | 2015-07-08 | Neumed | Pharmaceutical composition containing complex extract of aurantii nobilis pericarpium and crataegus as an active ingredient for treating or preventing obesity or lipid-related metabolic diseases |
| CN103638441A (en) * | 2013-12-15 | 2014-03-19 | 杜纪昌 | Traditional Chinese medicinal composition for treating fatty liver with liver stagnation and spleen deficiency symptom |
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Application publication date: 20160706 |