CN105726564A - Ointment for treating skin tinea - Google Patents

Ointment for treating skin tinea Download PDF

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Publication number
CN105726564A
CN105726564A CN201610186207.1A CN201610186207A CN105726564A CN 105726564 A CN105726564 A CN 105726564A CN 201610186207 A CN201610186207 A CN 201610186207A CN 105726564 A CN105726564 A CN 105726564A
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CN
China
Prior art keywords
ointment
parts
raw material
weight
dermatophytosis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610186207.1A
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Chinese (zh)
Inventor
李绍斌
王爱红
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Individual
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Individual
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Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201610186207.1A priority Critical patent/CN105726564A/en
Publication of CN105726564A publication Critical patent/CN105726564A/en
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/04Sulfur, selenium or tellurium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/60Salicylic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels

Abstract

The invention provides an ointment for treating skin tinea, belonging to the technical field of western medicines. The ointment comprises the following raw materials in parts by weight: 1-30 parts of sulfur, 1-10 parts of salicylic acid, 1-10 parts of borneol and 1-10 parts of benzoic acid. The ointment has the functions of killing bacteria and diminishing inflammation, relieving itching and removing dampness and astringing sores, is simple in formula and low in cost, has a wide range of application, is quick-acting and convenient and has a high cure rate.

Description

A kind of ointment treating dermatophytosis
Technical field
The present invention relates to a kind of ointment treating dermatophytosis.
Background technology
Dermatophytosis (dermatophytosis) is by the microbial hair of skin tinea, skin and the superficial infection referring to (toe) first, but It is currently also had to cause the report of deep infection.The most common person is favus of the scalp, ringworm of the body, jock itch, the tinea manuum, tinea pedis and dermatophytids Deng.Occasionally can involve deep tissue.Cause deep infection.Dermatophyte and metabolite thereof can be caused outside focus by blood circulation The allergy of skin, claims dermatophytids (dermatophytids).Dermatophytosis is one group of common disease and frequently-occurring disease.In dept. of dermatology In medical case, inferior to dermatitis and eczema, then rank first in infective factors.
Tinea disease is a kind of dermatomycosis, and the ointment treating dermatophytosis is healed for tinea disease the most relatively refractory.There are many treatments at present The externally applied drug of skin tinea, but great majority all contain cortin, and fungi can only be suppressed can not to kill fungi.And a lot of cream Agent is more greasy, hinders the absorption to medicine of the bleeding agent skin of medicine.Therefore treatment cycle is long, operates with inconvenience etc..
Summary of the invention
The present invention overcomes the deficiencies in the prior art, technical problem to be solved to be to provide one to have sterilizing and itch-relieving, toxic and side effect Little, the ointment for the treatment of dermatophytosis evident in efficacy.
For solving above-mentioned technical problem, the technical solution adopted in the present invention is: a kind of ointment treating dermatophytosis, by following The raw material composition of weight: sulphur 1-30 part, salicylic acid 1-10 part, borneol 1-10 part, benzoic acid 1-10 part.
Described a kind of ointment treating dermatophytosis, is made up of the raw material of following weight: 15 parts of sulphur, salicylic acid 8 Part, borneol 8 parts, 5 parts of benzoic acid.
The usage of described a kind of ointment treating dermatophytosis is to weigh the raw material of weight, soft with auxiliary element after smashing Cream base matter uniformly mixes, and then even application is in affected part, three times on the one;Favus of the scalp and jock itch apply sky recovery from illness in about 2 weeks, furuncle sore Apply recovery from illness in 1 week.
Institute's medicament component is 1:5 with the weight ratio of ointment bases.
Each drug component effect is as follows:
Sulphur: sulphur belongs to multipurpose agent, in addition to having bactericidal action, moreover it is possible to mite killing and desinsection.
Salicylic acid: for favus of the scalp, raw matter increasing office angle tinea and foot, salicylic acid can dissolve the structure formative substance between cutin, make angle Matter layer produces and comes off, so the cuticula that accumulation is blocked up can be removed, enhances metabolism.
Borneol: enter the heart, lung channel.Logical all keys, dissipate stagnated fire, remove screen improving eyesight, swelling and pain relieving.Control middle air port to keep silent, pyreticosis coma, Frightened epilepsy phlegm fan, deafness with qi stagnation, larynx numbness, aphtha, tympanitis, carbuncle swells, hemorrhoid, mesh also screen film, enterobiasis.
Benzoic acid: share in adult skin nosomycosis with salicylic acid, mycotic infection of superficial part such as ringworm of the body, the tinea manuum and tinea pedis etc..
Compared with prior art the invention have the advantages that.
The ointment of the present invention has bactericidal antiphlogistic, antipruritic, effect of old wet sore.Inventive formulation is simple, low cost, purposes Extensively, quick-acting, convenient, cure rate height.
Detailed description of the invention
Below in conjunction with specific embodiment, the invention will be further described.
Embodiment 1
A kind of ointment treating dermatophytosis, is made up of the raw material of following weight: 1 part of sulphur, salicylic acid 10 parts, ice Sheet 1 part, 10 parts of benzoic acid.
The usage of described a kind of ointment treating dermatophytosis is to weigh the raw material of weight, soft with auxiliary element after smashing Cream base matter uniformly mixes, and then even application is in affected part, three times on the one;Favus of the scalp and jock itch apply sky recovery from illness in about 2 weeks, furuncle sore Apply recovery from illness in 1 week.
Institute's medicament component is 1:5 with the weight ratio of ointment bases.
Embodiment 2
A kind of ointment treating dermatophytosis, is made up of the raw material of following weight: 15 parts of sulphur, salicylic acid 8 parts, ice Sheet 8 parts, 5 parts of benzoic acid.
The usage of described a kind of ointment treating dermatophytosis is to weigh the raw material of weight, soft with auxiliary element after smashing Cream base matter uniformly mixes, and then even application is in affected part, three times on the one;Favus of the scalp and jock itch apply sky recovery from illness in about 2 weeks, furuncle sore Apply recovery from illness in 1 week.
Institute's medicament component is 1:5 with the weight ratio of ointment bases.
Embodiment 3
Described a kind of ointment treating dermatophytosis, is made up of the raw material of following weight: 30 parts of sulphur, salicylic acid 1 Part, borneol 10 parts, 1 part of benzoic acid.
The usage of described a kind of ointment treating dermatophytosis is to weigh the raw material of weight, soft with auxiliary element after smashing Cream base matter uniformly mixes, and then even application is in affected part, three times on the one;Favus of the scalp and jock itch apply sky recovery from illness in about 2 weeks, furuncle sore Apply recovery from illness in 1 week.
Institute's medicament component is 1:5 with the weight ratio of ointment bases.
Embodiment 4
Described a kind of ointment treating dermatophytosis, is made up of the raw material of following weight: 20 parts of sulphur, salicylic acid 5 Part, borneol 5 parts, 5 parts of benzoic acid.
The usage of described a kind of ointment treating dermatophytosis is to weigh the raw material of weight, soft with auxiliary element after smashing Cream base matter uniformly mixes, and then even application is in affected part, three times on the one;Favus of the scalp and jock itch apply sky recovery from illness in about 2 weeks, furuncle sore Apply recovery from illness in 1 week.
Institute's medicament component is 1:5 with the weight ratio of ointment bases.
The clinical observation of medicinal ointment therapy dermatophytosis of the present invention
Out-patient's totally 40 example, the maleest 20 examples, female 20 example.20-30 age, 15 examples year, 31-40 year 15 examples, 41 years old -50 years old 6 examples, more than 50 years old 5 examples.Wherein favus of the scalp patient 28 example, jock itch patient 12 example.
Methods for the treatment of: morning, noon and afternoon every day smear ointment of the present invention, one week are a course for the treatment of, are used in conjunction 2 weeks.
Efficacy assessment standard:
Effective: after treatment, to observe 2 months thing recidivists.
Take a turn for the better: the obvious alleviator of symptom.
Invalid: not reach improvement standard.
Treatment results is shown in Table 1
Table 1 is observation of curative effect after treatment
Treatment number of days Effective Take a turn for the better Invalid Total effective rate
3 3 35 2 95%
7 15 25 0 100%
10 30 10 0 100%
14 35 5 0 100%
Table 1 result represents, with medicinal ointment therapy of the present invention 3 days, total effective rate just reached 95%, has treated 2 courses for the treatment of, the most effectively Rate 100%
The present invention can summarize with other the concrete form without prejudice to the spirit or essential characteristics of the present invention.Therefore, no matter from which From the point of view of a bit, the embodiment above of the present invention all can only be considered the description of the invention and can not limit invention, claim Book indicates the scope of the present invention, and the scope of the present invention is not pointed out in above-mentioned explanation, therefore, wants in the right with the present invention Ask any change in the implication and scope that book is suitable, be all considered as being included within the scope of the claims.

Claims (4)

1. the ointment treating dermatophytosis, it is characterised in that be made up of the raw material of following weight: sulphur 1-30 part, salicylic acid 1-10 part, borneol 1-10 part, benzoic acid 1-10 part.
A kind of ointment treating dermatophytosis the most according to claim 1, it is characterised in that be made up of the raw material of following weight: 15 parts of sulphur, salicylic acid 8 parts, borneol 8 parts, 5 parts of benzoic acid.
The usage of a kind of ointment treating dermatophytosis the most according to claim 1, it is characterised in that weighing the raw material of weight, uniformly mix with auxiliary element ointment bases after smashing, then even application is in affected part, three times on the one;Favus of the scalp and jock itch apply sky recovery from illness in about 2 weeks, and furuncle sore applies recovery from illness in 1 week.
The usage of a kind of ointment treating dermatophytosis the most according to claim 3, it is characterised in that institute's medicament component is 1:5 with the weight ratio of ointment bases.
CN201610186207.1A 2016-03-29 2016-03-29 Ointment for treating skin tinea Pending CN105726564A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610186207.1A CN105726564A (en) 2016-03-29 2016-03-29 Ointment for treating skin tinea

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610186207.1A CN105726564A (en) 2016-03-29 2016-03-29 Ointment for treating skin tinea

Publications (1)

Publication Number Publication Date
CN105726564A true CN105726564A (en) 2016-07-06

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107320519A (en) * 2017-08-29 2017-11-07 王红芝 One kind treats dermopathic ointment
CN109528756A (en) * 2017-09-21 2019-03-29 扬中牧乐药业有限公司 A kind of sulfur ointment for treating mink mange and scab

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1167626A (en) * 1996-06-10 1997-12-17 陈华 Medicament for treatment of various stubborn tineas
CN1435225A (en) * 2002-12-24 2003-08-13 黄宝田 Medical ointment Jiaoxuanxiao for treating beriberi
US20080249044A1 (en) * 2007-04-03 2008-10-09 Masaya Tanaka Nucleic acid external skin formulation
CN103127288A (en) * 2013-03-05 2013-06-05 谭鹏举 Medicament for treating beriberi and preparation method thereof
CN104147584A (en) * 2014-09-07 2014-11-19 吴俊� Medicine for treating beriberi and manufacturing method thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1167626A (en) * 1996-06-10 1997-12-17 陈华 Medicament for treatment of various stubborn tineas
CN1435225A (en) * 2002-12-24 2003-08-13 黄宝田 Medical ointment Jiaoxuanxiao for treating beriberi
US20080249044A1 (en) * 2007-04-03 2008-10-09 Masaya Tanaka Nucleic acid external skin formulation
CN103127288A (en) * 2013-03-05 2013-06-05 谭鹏举 Medicament for treating beriberi and preparation method thereof
CN104147584A (en) * 2014-09-07 2014-11-19 吴俊� Medicine for treating beriberi and manufacturing method thereof

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
潘俨若: "《小儿家庭用药须知》", 31 July 1993 *
邹长青: "《中药袖珍辞典》", 29 April 1996 *
陈莹,等: "HPLC法测定复方水杨酸冰片软膏中水杨酸和苯甲酸的含量", 《中国药品标准》 *
马振友: "《最新皮肤科药物手册》", 30 June 2008 *
马玉梅: "体碑、股癣等光皮癣切莫乱用药", 《首都医学》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107320519A (en) * 2017-08-29 2017-11-07 王红芝 One kind treats dermopathic ointment
CN109528756A (en) * 2017-09-21 2019-03-29 扬中牧乐药业有限公司 A kind of sulfur ointment for treating mink mange and scab

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SE01 Entry into force of request for substantive examination
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Application publication date: 20160706