CN105709143A - Yang warming and qi benefiting powder for treating cardiac failure and preparation method - Google Patents

Yang warming and qi benefiting powder for treating cardiac failure and preparation method Download PDF

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CN105709143A
CN105709143A CN201610197534.7A CN201610197534A CN105709143A CN 105709143 A CN105709143 A CN 105709143A CN 201610197534 A CN201610197534 A CN 201610197534A CN 105709143 A CN105709143 A CN 105709143A
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Abstract

The invention discloses yang warming and qi benefiting powder for treating cardiac failure and a preparation method. The yang warming and qi benefiting powder for treating cardiac failure is prepared from raw materials in parts by weight as follows: 25-35 parts of astragalus membranaceus, 3-9 parts of Poria cocos, 6-10 parts of cassia twig, 2-8 parts of sea buckthorn, 3-12 parts of oysters, 3-6 parts of rosewood heart wood, 4-9 parts of danshen root, 5-9 parts of mussels, 2-5 parts of stemona root, 3-9 parts of common anemarrhena rhizome, 6-9 parts of bryozoatum, 4-10 parts of oriental waterplantain rhizome and 6-12 parts of ageratum conyzoides. The selected raw materials are all traditional Chinese medicine materials and do not have any toxic and side effects; the formula completely meets the principle of traditional Chinese medicine and physical and mental characteristics of a patient with the cardiac failure; different formulae can be applied according to different crowds under the premise of the overall principle, functions are different, medicinal herbs resources are available, the medicinal material cost is low, and the burden of the patient can be relieved.

Description

Heart failure warming YANG and invigorating QI dissipates and preparation method
Divisional application, original applying number 2014100822241, applying date 2014.03.07, title heart failure warming YANG and invigorating QI Dissipate and preparation method.
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to one treat heart failure warming YANG and invigorating QI dissipate and preparation side Method.
Background technology
Heart failure is also referred to as congestive heart failure or cardiac insufficiency.Heart weakens because of disease, overwork, ejection function, So that blood discharge amount can not meet organ and anabolic needs.Cardinal symptom is dyspnea, pant, edema etc..Due to the heart Myotility weakens cardiac output decline to such an extent as to pulmonary circulation or and the body circulation stasis of blood occur simultaneously in tissue and organ perfusion amount deficiency The performance of blood.
Heart failure is not an independent disease, refers to that the various cause of disease causes cardiopathic severe stage.Sickness rate is high, and five Annual survival rate is similar to malignant tumor.Heart failure is due to initial cardiac damage and stress effect: includes systole or relaxes Open phase ventricle overload, the change (interim such as myocardial infarction, diffusivity such as myocarditis) of number of myocardial cells and quality, draw Playing ventricle and (or) atrial hypertrophy and expansion, Ventricular Remodeling, continue low with ventricle systolic and diastolic function, gradually development forms.Cardiac valve Disease, coronary atherosclerosis, hypertension, endocrine disorder, bacteriotoxin, acute lung infraction, emphysema or other chronic lungs Illness etc. all can cause heart disease to produce the performance of heart failure.Gestation, tired, intravenous a large amount of fluid infusion rapidly etc. all can add The burden of the ill heart of weight, and induce heart failure.
1. heart failure refers to the heart failure caused by constitutional myocardium myo fibril contractile dysfunction, now pumping function Obstacle is primary.Cardiac muscle shrinks unable because of various reasons, it is impossible to spray enough blood in the blood vessel of periphery with whole body Anabolic when needing, just there is heart failure.2. the heart failure that other reasons causes.During such as valvular heart disease, due to Myocardial muscle load is overweight and myocardial hypertrophy and cardiac dilatation occur, and continues, myocardial contractility relative deficiency and cause heart failure, this Time pumping function obstacle be secondary, remove valvular malfunctions time be easier to reverse.3. the heart failure caused by the reason beyond cardiac muscle Exhaust, the most also with cardiac damage.4. except the disease of heart itself, such as congenital heart disease, myocarditis, cardiac muscle Sick, serious arrhythmia, endocarditis etc., the disease beyond heart, such as acute nephritis, toxic pneumonitis, anemia, molten Complication of blood, a large amount of vein fluid infusion and surgical site infections etc., it is also possible to cause heart failure.
Comparing with western medicine and medical practitioners, by Chinese traditional treatment, toxic and side effects is relatively light, is more vulnerable to numerous medical personnels Favor with friend patient.Authorization Notice No. CN 102145089 B(application number 201110082149.5) Chinese patent literary composition Offer and provide a kind of Chinese medicine treating heart failure, be size-reduced by each component of following weight portion, sieve, be obtained by mixing:
Radix Astragali 250-270 part, Ramulus Cinnamomi 100-110 part, Radix Rhodiolae 50-65 part, Radix Salviae Miltiorrhizae 150-160 part, Rhizoma Alismatis 150-160 Part, Semen Lepidii (Semen Descurainiae) 150-160 part.Application publication number CN 103006936 A(application number 201210518700.0) China specially Profit document relates to a kind of pill treating heart failure: the pill of described treatment heart failure by following component according to weight Number forms: Radix Codonopsis 5-7 part, Radix Polygalae 2-8 part, Radix Notoginseng 6-9 part, Poria 2-7 part, Radix Glycyrrhizae Preparata 3-5 part, Radix Astragali 5-9 part, Rhizoma Alismatis 6-8 part, Radix Salviae Miltiorrhizae 4-9 part, Caulis Spatholobi 2-6 part.Application publication number CN 103285369 A(application number 201310281596.2) a kind of Chinese medicine composition treating heart failure is related to: by the crude drug system of following weight portion Become: Radix Astragali 12-24 part, Poria 12-24 part, Fructus Aurantii Immaturus 12-24 part, Semen Lepidii (Semen Descurainiae) 12-24 part, Cortex Mori 8-16 part, Radix Paeoniae Rubra 8- 16 parts, Radix Codonopsis 8-16 part, Ramulus Cinnamomi 7-13 part, Fructus Jujubae 7-13 part, Rhizoma Alismatis 7-13 part, Radix Aconiti Lateralis Preparata 6-8 part, Radix Glycyrrhizae 6-8 part, Rhizoma Atractylodis Macrocephalae 6-8 part, Radix Ginseng Rubra 4-6 part, Cortex Acanthopancis 4-6 part, Os Draconis 4-6 part, Rhizoma Zingiberis 4-6 part.
Although the medicine provided in prior art the most all has some curative effects on treatment heart failure, but part Prescription brings certain toxic and side effects, the most existing technology all not to have temperature more or less can to the gastrointestinal of patient, Liver and kidney Effect of sun QI invigorating.Generally speaking, treatment for heart failure at present there is no preferable definite treatment by Chinese herbs medicine.
Summary of the invention
For the deficiencies in the prior art, it is an object of the invention to provide one prepare simply, taking convenience, be easy to carry, The heart failure warming YANG and invigorating QI of clothes dissipates and preparation method the most for a long time.This electuary determined curative effect and having no side effect.
The technical scheme is that
Heart failure warming YANG and invigorating QI dissipates, and is mainly prepared from by following bulk drugs, is weight portion: Radix Astragali 25-35, Poria 3-9, Ramulus Cinnamomi 6-10, Fructus Hippophae 2-8, Concha Ostreae 3-12, Lignum Dalbergiae Odoriferae 3-6, Radix Salviae Miltiorrhizae 4-9, Mytilus 5-9, Radix Stemonae 2-5, Rhizoma Anemarrhenae 3-9, Pumex 6-9, Rhizoma Alismatis 4-10, Herba Agerati Conyzoidis 6-12.
Foregoing heart failure warming YANG and invigorating QI dissipates, it is preferred that is mainly prepared from by following bulk drugs, all attaches most importance to Amount part: Radix Astragali 28-33, Poria 5-7, Ramulus Cinnamomi 7-9, Fructus Hippophae 4-6, Concha Ostreae 5-10, Lignum Dalbergiae Odoriferae 4-5, Radix Salviae Miltiorrhizae 6-8, Mytilus 6-8, the Radix Stemonae 3-4, Rhizoma Anemarrhenae 5-7, Pumex 7-8, Rhizoma Alismatis 6-8, Herba Agerati Conyzoidis 8-10.
Foregoing heart failure warming YANG and invigorating QI dissipates, and the most preferably, is mainly prepared from by following bulk drugs, all For weight portion: the Radix Astragali 25, Poria 6, Ramulus Cinnamomi 8, Fructus Hippophae 5, Concha Ostreae 8, Lignum Dalbergiae Odoriferae 4.5, Radix Salviae Miltiorrhizae 7, Mytilus 7, the Radix Stemonae 3.5, the Rhizoma Anemarrhenae 6, sea Pumex 7.5, Rhizoma Alismatis 7, Herba Agerati Conyzoidis 9.
The preparation method that described heart failure warming YANG and invigorating QI dissipates is:
(1) juice is decocted in the crude drug mixing put in order, decoct altogether three times, every time after water boils, then decoct 0.5-1.2 hour, cross leaching Juice, medicine juice merges, and by thin film evaporation to every milliliter contained 1-2 gram, the ethanol (95%) adding one times of weight is stirring while adding, Filter after precipitating 8-24 hour；
(2) filtrate is by thin film evaporation to every milliliter of suitable 4-5 gram of crude drug of medicinal liquid, adds cold water and is diluted to every milliliter contained 1-2 Gram, filter after precipitating 8-24 hour；
(3) filtrate is 1.1-1.2:1 by thin film evaporation to extractum shape, concentrated solution specific gravity control, lets cool to 80 DEG C the most admittedly The scale of construction；
(4) add the white sugar of total solid 2-5 times weight, the dextrin of 0.5-1.2 times of (preferably 0.9 times) weight, use ethanol (65%), regulate humidity, make granule with granulation machine, packaging.
The preparation method that above-mentioned heart failure warming YANG and invigorating QI dissipates, it is preferred that step (1) decocts 0.7-1 hour (preferably again 0.8 hour).
The preparation method that above-mentioned heart failure warming YANG and invigorating QI dissipates, it is preferred that step (1) filters after precipitating 13-18 hour (preferably 15 hours).
The preparation method that above-mentioned heart failure warming YANG and invigorating QI dissipates, it is preferred that it is suitable that step (2) is evaporated to every milliliter of medicinal liquid Crude drug 4.2-4.8 gram (preferably 4.5 grams).
The preparation method that above-mentioned heart failure warming YANG and invigorating QI dissipates, it is preferred that step (2) filters after precipitating 13-18 hour (preferably 15 hours).
The preparation method that above-mentioned heart failure warming YANG and invigorating QI dissipates, it is preferred that step (4) adds total solid 3-4 times weight White sugar (preferably 3.5 times).
Dissipate according to heart failure warming YANG and invigorating QI described in above any one and additionally provide at preparation treatment pulmonary heart disease, cardiac muscle stalk Application in plug, myocardial necrosis, anginal medicine.
Instructions of taking: for making the present invention reach optimum efficiency, when taking, each one bag, three times a day, and warm boiled water, 7 It course for the treatment of.
Used by the present invention, the pharmacology of main raw material of Chinese medicine is as follows:
The Radix Astragali: nature and flavor: sweet, temperature.Gui Jing: return lung, spleen channel.Effect: invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Main Controlling: weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle is difficult Bursting, burst for a long time and do not hold back, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst；Chronic nephritis proteinuria, diabetes
Poria: nature and flavor: sweet, light is flat.Gui Jing: GUIXIN, lung, spleen, kidney channel.Effect: promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.Cure mainly: For edema oliguria. phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, loose stool has loose bowels, irritability, palpitation with fear insomnia.
Ramulus Cinnamomi: nature and flavor: acrid, sweet, warm.Gui Jing: GUIXIN, lung, bladder warp.Effect: diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian is supporing yang Activating QI, the flat gas that spins.Cure mainly: for anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, run quickly Globefish.
Fructus Hippophae: another name Da Er, Fructus Elaeagni Angustifoliae, fructus hippophae, big Er Buxing, vinegar willow, acid sting Liu Liu, sour, its examine a day Cannes, acid thorn, Black thorn, yellow acid thorn, acid thorn thorn, Fructus Hippophae and oil have the highest medical value, it is possible to decrease cholesterol, cure angina pectoris etc. and make With, also prevent and treat the effect of coronary atherosclerotic heart disease；Have and eliminate the phlegm, cough-relieving, relieving asthma and treat chronic tracheitis Effect；Gastric duodenal ulcer and dyspepsia etc. can be treated, to chronic superficial gastritis, atrophic gastritis, colitis Evident in efficacy etc. disease；To burn, scald, cutter burns, cold injury has good therapeutical effect；Cervical erosion is had good controlling Therapeutic effect.Sour in the mouth；Puckery；Warm in nature, relieving cough and resolving phlegm；Invigorating the stomach and promoting digestion；Promoting blood circulation to remove blood stasis.Main cough with copious phlegm；Pulmonary abscess；Dyspepsia；Food Long-pending stomachache；Stomachache；Enteritis；Amenorrhea；Traumatic injury congestive edema.
Concha Ostreae: nature and flavor: salty, is slightly cold.Gui Jing: return liver, gallbladder, kidney channel.Effect: tranquillization with heavy prescription, YANG hyperactivity suppressing nourishing YIN, softening the hard mass dissipates Knot, restrains astringent or styptic treatment for spontaneous sweating.Cure mainly: be used for insomnia of palpitating with fear, vertigo and tinnitus, scrofula sucutaneous nodule, abdominal mass mass in the abdomen, spontaneous sweating, metrorrhagia and leukorrhagia of passing out semen, Stomachache acid regurgitation.
Radix Salviae Miltiorrhizae: nature and flavor: bitter, is slightly cold.Gui Jing: GUIXIN, Liver Channel.Effect: stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, clear away heart-fire relieving restlessness. Cure mainly: for menoxenia, amenorrhea dysmenorrhea, abdominal mass accumulation, chest and abdomen twinge, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia；Liver spleen Enlargement, angina pectoris.
Mytilus: salty, temperature.Invigorating the liver and kidney, benefiting essence-blood, disappear goiter.Control asthenia weakness and emaciation, dizziness, night sweat, sexual impotence, lumbago, spit blood, Metrorrhagia, leukorrhagia, goiter, hernia abdominal mass.Energy tonifying five ZANG-organs, Yiyang thing, manage waist tinea pedis, disappear dyspepsia, except cold air in abdomen, mass beside the umbilicus.
Lignum Dalbergiae Odoriferae: nature and flavor: pungent, temperature.Gui Jing: return liver, spleen channel.Effect: promoting flow of QI and blood, pain relieving, hemostasis.Cure mainly: be used for Epigastric pain. hypochondriac pain due to stagnation of liverQI, thoracic obstruction twinge, injury from falling down, traumatic hemorrhage.
The Radix Stemonae: nature and flavor: sweet, bitter, tepor.Gui Jing: return lung meridian.Effect: nourishing the lung to keep the adverse QI downward cough-relieving, parasite killing.Cure mainly: use Cough in new chronic cough, pulmonary tuberculosis cough, pertussis；Outer for head louse, body louse, enterobiasis, pudendal pruritus.Honey Radix Stemonae nourishing the lung to arrest cough.For the moon Asthenia is coughed.
Herba Agerati Conyzoidis: hardship pungent, micro-is cool.Function cures mainly: expelling wind and clearing away heat, pain relieving, hemostasis, calculus.For upper respiratory tract infection, Tonsillitis, pharyngolaryngitis, acute gastroenteritis, stomachache, stomachache, metrorrhagia, renal calculus, vesical calculus；Eczema is controlled in external, thrush, Ulcerative carbuncle toxic swelling, cellulitis, ulcer of the lower limb, otitis media, traumatic hemorrhage.
The Rhizoma Anemarrhenae: nature and flavor: bitter, sweet, cold.Gui Jing: return lung, stomach, kidney channel.Effect: clearing away heat-fire, promotes the production of body fluid and moisturizes.Cure mainly: For fever caused by exogenous pathogenic factors. high hot excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat quenches one's thirst, dryness of the intestine constipation.
Pumex: salty, cold.Lung；Kidney；Liver；Large intestine channel.Action and efficacy editor's lung heat clearing fire, changes old expectorant, and softening the hard mass is treating stranguria.Control expectorant Dyspnea of heat type is coughed, old accumulation of phlegm block, goiter, scrofula, gonorrhea, hernia, and skin ulcer swells, corneal nebula.Removing heat from the lung and dissipating phlegm, hard masses softening and resolving.For cough due to lung-heat, Yellowish thick sputum, spitting of blood, bronchitis, tuberculous lymphadenitis.
Rhizoma Alismatis: nature and flavor: sweet, cold.Gui Jing: return kidney, bladder warp.Effect: diuresis, clearing away damp-heat.Cure mainly: for urine Unfavorable. edema distension, oliguria of having loose bowels, dizziness due to fluid-retention, the puckery pain of pyretic stranguria；Hyperlipidemia.
The Chinese medicine composition scientific formula that the present invention provides, the preparation method of its dosage form is simple, products obtained therefrom taking convenience, It is easy to carry.In addition, the excellent results of the present invention is also manifested by:
1, selected materials is all Chinese medicine material, without any side effects；
2, this prescription complies fully with Chinese medicine principle and heart failure, cardiac's body and mind feature, on the premise of general principle, Can have different prescription according to different crowd, function is different, most importantly can play effect of warming YANG and invigorating QI.
3, medicine source is easy to get, and medical material is with low cost, it is possible to alleviate patient burden.
Detailed description of the invention
Describe technical scheme in detail below in conjunction with embodiment and experimental example, but protection domain is not limited to this.
Embodiment 1 heart failure warming YANG and invigorating QI dissipates, and is mainly prepared from by following bulk drugs, is weight portion (every part 5g): the Radix Astragali 25, Poria 3, Ramulus Cinnamomi 6, Fructus Hippophae 2, Concha Ostreae 3, Lignum Dalbergiae Odoriferae 3, Radix Salviae Miltiorrhizae 4, Mytilus 5, the Radix Stemonae 2, the Rhizoma Anemarrhenae 3, Pumex 6, Rhizoma Alismatis 4, Herba Agerati Conyzoidis 6.
The preparation method that above-mentioned heart failure warming YANG and invigorating QI dissipates:
(1) juice is decocted in the crude drug mixing put in order, decoct altogether three times, every time after water boils, then decoct 0.5 hour, filter extracting juice, medicine Juice merges, and by thin film evaporation to every milliliter contained 1-2 gram, the ethanol (95%) adding one times of weight is stirring while adding, precipitates 8 Filter after hour；
(2) filtrate is by thin film evaporation to every milliliter of suitable 4 grams of crude drugs of medicinal liquid, adds cold water and is diluted to every milliliter contained 1-2 gram, Filter after precipitating 8 hours；
(3) filtrate is 1.1-1.2:1 by thin film evaporation to extractum shape, concentrated solution specific gravity control, lets cool to 80 DEG C the most admittedly The scale of construction；
(4) add the white sugar of total solid 2-5 times weight, the dextrin of 0.5 times of weight, with ethanol (65%), regulate humidity, use Granulation machine makes granule, packaging.
Model case one: field xx, man, 87 years old, retirement doctor, from 1964, without obvious inducement, paroxysmal cough occurs, Expectoration, white mucus expectorant, sputum mixed with blood silk sometimes, it was diagnosed as at that time " bronchitis ", alleviated after penicillin treatment.Hereafter weather Cool off and winter-spring season recurrent exerbation, take a turn for the better after taking antibiotic and cough suppressing medicine.Cough after nineteen ninety-five, expectoration increases the weight of, and morning rises Aggravation, coughs white foam expectorant, feels cardiopalmus, tachypnea such as stair climbing, skelp etc., can alleviate after rest after activity, and in JIUYUE, 2003 is drenched After rain, cough increases the weight of, coughs yellow purulent sputum, and amount is few, difficult expectoration, accompanies obvious tachypnea, cardiopalmus and edema of pair of lower extremities.In locality first After give cefoperazone, lomefloxacin, aminophylline and treatment by Chinese herbs, improve inconspicuous, walk level road and also feel and breathing hard.After suffering from cold before 10 days Sense cardiopalmus, tachypnea increase the weight of again, and night can not put down sleeping, and urine amount reduces, and has low grade fever, and body temperature fluctuation is at 37.5 DEG C--and 38.0 DEG C, Cough, coughs white mucus expectorant, many about 100ml every day of amount, without night sweat, chest pain and spitting of blood, the oxygen uptake and taking of being in is brought down a fever, cough-relieving, After Apophlegmatisant, symptom is without alleviating, and outpatient service is with " chronic bronchitis, emphysema, heart failure respiratory failure " Shou Ren institute.Both Being good for toward body, have 55 years smoking histories, every day, 20--30 propped up, and gave up smoking in nineteen ninety-five, without drinking hobby, because patient age is bigger, So doctor advised its take warming YANG and invigorating QI of the present invention dissipate.
Take embodiment 1 gained treatment heart failure warming YANG and invigorating QI to dissipate, each one bag, three times a day, warm boiled water, 7 days One course for the treatment of.Taking 21 days, chest pain, cough alleviate, and the most confusing also alleviate, and the amount of receiving increases, spirit can, take 5 months, symptom disappears Removing, peace of sleeping night, vexed remove, strength increases, receive food can, following the service 12 months, any discomfort does not occurs when patient takes, self-induction is fully recovered.
Embodiment 2 heart failure warming YANG and invigorating QI dissipates, and is mainly prepared from by following bulk drugs, is weight portion (every part 10g): the Radix Astragali 35, Poria 9, Ramulus Cinnamomi 10, Fructus Hippophae 8, Concha Ostreae 12, Lignum Dalbergiae Odoriferae 6, Radix Salviae Miltiorrhizae 9, Mytilus 9, the Radix Stemonae 5, the Rhizoma Anemarrhenae 9, Pumex 9, Rhizoma Alismatis 10, Herba Agerati Conyzoidis 12.
The preparation method that above-mentioned heart failure warming YANG and invigorating QI dissipates is:
(1) juice is decocted in the crude drug mixing put in order, decoct altogether three times, every time after water boils, then decoct 1.2 hours, filter extracting juice, medicine Juice merges, and by thin film evaporation to every milliliter contained 1-2 gram, the ethanol (95%) adding one times of weight is stirring while adding, precipitates 24 Filter after hour；
(2) filtrate is by thin film evaporation to every milliliter of suitable 5 grams of crude drugs of medicinal liquid, adds cold water and is diluted to every milliliter contained 1-2 gram, Filter after precipitating 24 hours；
(3) filtrate is 1.1-1.2:1 by thin film evaporation to extractum shape, concentrated solution specific gravity control, lets cool to 80 DEG C the most admittedly The scale of construction；
(4) add the white sugar of 5 times of weight of total solid, the dextrin of 1.2 times of weight, with ethanol (65%), regulate humidity, use Granule made by grain machine, packaging.
Embodiment 3 heart failure warming YANG and invigorating QI dissipates, and is mainly prepared from by following bulk drugs, is weight portion (every part 15g): the Radix Astragali 28, Poria 5, Ramulus Cinnamomi 7, Fructus Hippophae 4, Concha Ostreae 5, Lignum Dalbergiae Odoriferae 4, Radix Salviae Miltiorrhizae 6, Mytilus 6, the Radix Stemonae 3, the Rhizoma Anemarrhenae 5, Pumex 7, pool Rush down 6, Herba Agerati Conyzoidis 8.
The preparation method that above-mentioned heart failure warming YANG and invigorating QI dissipates is:
(1) juice is decocted in the crude drug mixing put in order, decoct altogether three times, every time after water boils, then decoct 0.7 hour, filter extracting juice, medicine Juice merges, and by thin film evaporation to every milliliter contained 1-2 gram, the ethanol (95%) adding one times of weight is stirring while adding, precipitates 13 Filter after hour；
(2) filtrate is by thin film evaporation to every milliliter of suitable 4.2 grams of crude drugs of medicinal liquid, adds cold water and is diluted to every milliliter contained 1-2 Gram, filter after precipitating 13 hours；
(3) filtrate is 1.1-1.2:1 by thin film evaporation to extractum shape, concentrated solution specific gravity control, lets cool to 80 DEG C the most admittedly The scale of construction；
(4) add the white sugar of 3 times of weight of total solid, the dextrin of 0.8 times of weight, with ethanol (65%), regulate humidity, use Granule made by grain machine, packaging.
Model case two: poplar xx, women, 54 years old, people from Hanzhong.Patient has asthma medical history more than 30 year, the most often coughs Cough, and feel asthma, out of breath and feel suffocated.In January, 2006 unexpected exacerbation of symptoms, sweating due to debility is dripping, lower limbs edema, green around the gills emergency treatment Rescuing at local hospital, cardiac function level Four at that time, Color Sonography prompting expands whole-heartedly, heart failure, lung A high pressure.Owing to the state of an illness is critical, Local doctor informs that patient treatment is wished not quite.
For seeking preferably to treat, patient started to take embodiment 3 gained treatment heart failure warming YANG benefit in March, 2010 Gas dissipates, each one bag, three times a day, warm boiled water, 7 days courses for the treatment of, to take 21 days, precordialgia, cough alleviate, tired Weary unable also alleviating, the amount of receiving increases, spirit can, take 5 months, electrocardio diagram coronary artery blood supply is obviously improved, following the service 12 months, Patient's self-induction is fully recovered.
Embodiment 4 heart failure warming YANG and invigorating QI dissipates, and is mainly prepared from by following bulk drugs, is weight portion (every part 20g): the Radix Astragali 33, Poria 7, Ramulus Cinnamomi 9, Fructus Hippophae 6, Concha Ostreae 10, Lignum Dalbergiae Odoriferae 5, Radix Salviae Miltiorrhizae 8, Mytilus 8, the Radix Stemonae 4, the Rhizoma Anemarrhenae 7, Pumex 8, pool Rush down 8, Herba Agerati Conyzoidis 10.
The preparation method that above-mentioned heart failure warming YANG and invigorating QI dissipates is:
(1) juice is decocted in the crude drug mixing put in order, decoct altogether three times, every time after water boils, then decoct 1 hour, filter extracting juice, medicine juice Merging, by thin film evaporation to every milliliter contained 1-2 gram, the ethanol (95%) adding one times of weight is stirring while adding, and precipitation 18 is little Filter time after；
(2) filtrate is by thin film evaporation to every milliliter of suitable 4.8 grams of crude drugs of medicinal liquid, adds cold water and is diluted to every milliliter contained 1-2 Gram, filter after precipitating 18 hours；
(3) filtrate is 1.1-1.2:1 by thin film evaporation to extractum shape, concentrated solution specific gravity control, lets cool to 80 DEG C the most admittedly The scale of construction；
(4) add the white sugar of 4 times of weight of total solid, the dextrin of 1 times of weight, with ethanol (65%), regulate humidity, use granule Granule made by machine, packaging.
Embodiment 5 heart failure warming YANG and invigorating QI dissipates, and is mainly prepared from by following bulk drugs, is weight portion (every part 30g): the Radix Astragali 25, Poria 6, Ramulus Cinnamomi 8, Fructus Hippophae 5, Concha Ostreae 8, Lignum Dalbergiae Odoriferae 4.5, Radix Salviae Miltiorrhizae 7, Mytilus 7, the Radix Stemonae 3.5, the Rhizoma Anemarrhenae 6, Pumex 7.5, Rhizoma Alismatis 7, Herba Agerati Conyzoidis 9.
The preparation method that above-mentioned heart failure warming YANG and invigorating QI dissipates is:
(1) juice is decocted in the crude drug mixing put in order, decoct altogether three times, every time after water boils, then decoct 0.8 hour, filter extracting juice, medicine Juice merges, and by thin film evaporation to every milliliter contained 1-2 gram, the ethanol (95%) adding one times of weight is stirring while adding, precipitates 15 Filter after hour；
(2) filtrate is by thin film evaporation to every milliliter of suitable 4.5 grams of crude drugs of medicinal liquid, adds cold water and is diluted to every milliliter contained 1-2 Gram, filter after precipitating 15 hours；
(3) filtrate is 1.1-1.2:1 by thin film evaporation to extractum shape, concentrated solution specific gravity control, lets cool to 80 DEG C the most admittedly The scale of construction；
(4) add the white sugar of 3.5 times of weight of total solid, the dextrin of 0.9 times of weight, with ethanol (65%), regulate humidity, use Granulation machine makes granule, packaging.
The clinical practice that test example 1 embodiment 5 gained treatment heart failure warming YANG and invigorating QI dissipates: in JIUYUE, 2008-2013 years December, screens 300 example heart failure patients, wherein women 150 example in 3 second-rank first class hospitals, and male 150 example is the oldest 85 years old, minimal ages 35 years old, 62 years old mean age.Before test 2 weeks, this crowd is carried out Continuous Observation, record symptom and Change, is randomly divided into two groups, experimental group and matched group, and experimental group takes embodiment 5 products obtained therefrom, and matched group takes other medicine (conventional medication such as pills for curing heart disease, metoprolol).Using method is: each one bag, three times a day, warm boiled water, treatment in 10 days Journey.Curative effect situation criterion: cure: taking 3 courses for the treatment of of this product, cough is obviously improved, malaise symptoms disappears, energy and muscle power It is remarkably reinforced；Effective: to take 3 courses for the treatment of of this product, cough symptom alleviates, and malaise symptoms alleviates or partial disappearance, energy and muscle power Strengthen；Invalid: taking 3 courses for the treatment of of this product, malaise symptoms is unchanged.Result is as shown in table 1.
Table 1: take embodiment 5 product 35-75 year heart failure crowd's therapeutic outcome
Using warming YANG and invigorating QI of the present invention to be dispersed on treatment heart failure, effect is notable, clinical tests prove that effective percentage is 95%, Cure rate is 70%, and compared with oral western medicine, effective percentage is high by 25%, and cure rate is high by 40%, and is not required to take other treatment heart failure again The medicine exhausted carries out auxiliary treatment, alleviates patient body and burden economically；With nitroglycerin class treatment heart failure Medicine is compared, and effective percentage is high by 10%, and cure rate is high by 45%, and symptom when can not only alleviate episode of heart failure, moreover it is possible to thoroughly Treating heart failure and play the effect of warming YANG and invigorating QI, therefore, it is that a kind of curative effect comprehensively treats the heart that warming YANG and invigorating QI of the present invention dissipates The medicine of force failure warming YANG and invigorating QI.

Claims (7)

1. heart failure warming YANG and invigorating QI dissipates, and it is characterized in that, is mainly prepared from by following bulk drugs, is weight portion: the Radix Astragali 25, Poria 3, Ramulus Cinnamomi 6, Fructus Hippophae 2, Concha Ostreae 3, Lignum Dalbergiae Odoriferae 3, Radix Salviae Miltiorrhizae 4, Mytilus 5, the Radix Stemonae 2, the Rhizoma Anemarrhenae 3, Pumex 6, Rhizoma Alismatis 4, Herba Agerati Conyzoidis 6.
The preparation method that the most according to claim 1, heart failure warming YANG and invigorating QI dissipates, is characterized in that, step is as follows:
(1) juice is decocted in the crude drug mixing put in order, decoct altogether three times, every time after water boils, then decoct 0.5-1.2 hour, cross leaching Juice, medicine juice merges, and by thin film evaporation to every milliliter contained 1-2 gram, the ethanol (95%) adding one times of weight is stirring while adding, Filter after precipitating 8-24 hour；
(2) filtrate is by thin film evaporation to every milliliter of suitable 4-5 gram of crude drug of medicinal liquid, adds cold water and is diluted to every milliliter contained 1-2 Gram, filter after precipitating 8-24 hour；
(3) filtrate is 1.1-1.2:1 by thin film evaporation to extractum shape, concentrated solution specific gravity control, lets cool to 80 DEG C the most admittedly The scale of construction；
(4) add the white sugar of total solid 2-5 times weight, the dextrin of 0.5-1.2 times of (preferably 0.9 times) weight, use ethanol (65%), regulate humidity, make granule with granulation machine, packaging.
Preparation method the most according to claim 2, is characterized in that, step (1) decocts 0.7-1 hour (preferably 0.8 hour) again.
Preparation method the most according to claim 2, is characterized in that, step (1) filters (preferably 15 after precipitating 13-18 hour Hour).
Preparation method the most according to claim 2, is characterized in that, step (2) is evaporated to every milliliter of suitable crude drug of medicinal liquid 4.2-4.8 gram (preferably 4.5 grams).
Preparation method the most according to claim 2, is characterized in that, step (2) filters (preferably 15 after precipitating 13-18 hour Hour).
Preparation method the most according to claim 2, is characterized in that, step (4) adds the white sugar of total solid 3-4 times weight (preferably 3.5 times).
CN201610197534.7A 2014-03-07 2014-03-07 Yang warming and qi benefiting powder for treating cardiac failure and preparation method Withdrawn CN105709143A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102652779A (en) * 2011-03-02 2012-09-05 黄继汉 Traditional Chinese medicine particle for treating refractory heart failure and preparation method thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102652779A (en) * 2011-03-02 2012-09-05 黄继汉 Traditional Chinese medicine particle for treating refractory heart failure and preparation method thereof

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* Cited by examiner, † Cited by third party
Title
余洪刚，等: "温阳补心汤配合西药治疗慢性心力衰竭34例", 《陕西中医》 *
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