CN105709090A - 一种用于治疗小儿咳喘的中药颗粒 - Google Patents
一种用于治疗小儿咳喘的中药颗粒 Download PDFInfo
- Publication number
- CN105709090A CN105709090A CN201610105317.0A CN201610105317A CN105709090A CN 105709090 A CN105709090 A CN 105709090A CN 201610105317 A CN201610105317 A CN 201610105317A CN 105709090 A CN105709090 A CN 105709090A
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- asthma
- fructus
- semen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008187 granular material Substances 0.000 title claims abstract description 29
- 206010011224 Cough Diseases 0.000 title abstract description 20
- 208000006673 asthma Diseases 0.000 title abstract description 12
- 210000000582 semen Anatomy 0.000 claims abstract description 22
- 244000236655 Diospyros kaki Species 0.000 claims abstract description 8
- 241000756943 Codonopsis Species 0.000 claims abstract description 7
- 241000628997 Flos Species 0.000 claims description 24
- 208000035756 Infantile asthma Diseases 0.000 claims description 20
- 239000002994 raw material Substances 0.000 claims description 11
- 239000000203 mixture Substances 0.000 claims description 10
- 239000000341 volatile oil Substances 0.000 claims description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 10
- 235000008597 Diospyros kaki Nutrition 0.000 claims description 7
- 241001643642 Viticis Species 0.000 claims description 7
- OSGAYBCDTDRGGQ-UHFFFAOYSA-L calcium sulfate Chemical compound [Ca+2].[O-]S([O-])(=O)=O OSGAYBCDTDRGGQ-UHFFFAOYSA-L 0.000 claims description 7
- MYSWGUAQZAJSOK-UHFFFAOYSA-N ciprofloxacin Chemical compound C12=CC(N3CCNCC3)=C(F)C=C2C(=O)C(C(=O)O)=CN1C1CC1 MYSWGUAQZAJSOK-UHFFFAOYSA-N 0.000 claims description 7
- 238000010438 heat treatment Methods 0.000 claims description 7
- 238000002360 preparation method Methods 0.000 claims description 6
- 229920001353 Dextrin Polymers 0.000 claims description 5
- 239000004375 Dextrin Substances 0.000 claims description 5
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 5
- 229930006000 Sucrose Natural products 0.000 claims description 5
- 238000009835 boiling Methods 0.000 claims description 5
- 235000019425 dextrin Nutrition 0.000 claims description 5
- 238000001035 drying Methods 0.000 claims description 5
- 238000000605 extraction Methods 0.000 claims description 5
- 239000000706 filtrate Substances 0.000 claims description 5
- 239000000047 product Substances 0.000 claims description 5
- 238000010298 pulverizing process Methods 0.000 claims description 5
- 238000010992 reflux Methods 0.000 claims description 5
- 238000001256 steam distillation Methods 0.000 claims description 5
- 238000003756 stirring Methods 0.000 claims description 5
- 239000005720 sucrose Substances 0.000 claims description 5
- 239000000284 extract Substances 0.000 claims description 2
- 241000208340 Araliaceae Species 0.000 claims 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims 1
- 235000003140 Panax quinquefolius Nutrition 0.000 claims 1
- 235000008434 ginseng Nutrition 0.000 claims 1
- 239000003814 drug Substances 0.000 abstract description 10
- 230000000694 effects Effects 0.000 abstract description 6
- 210000004072 lung Anatomy 0.000 abstract description 5
- 206010036790 Productive cough Diseases 0.000 abstract description 2
- 239000000463 material Substances 0.000 abstract description 2
- 238000005728 strengthening Methods 0.000 abstract description 2
- 235000013399 edible fruits Nutrition 0.000 abstract 2
- 206010067484 Adverse reaction Diseases 0.000 abstract 1
- 244000144725 Amygdalus communis Species 0.000 abstract 1
- 235000011437 Amygdalus communis Nutrition 0.000 abstract 1
- MCTQNEBFZMBRSQ-GEEYTBSJSA-N Chrysoidine Chemical compound Cl.NC1=CC(N)=CC=C1\N=N\C1=CC=CC=C1 MCTQNEBFZMBRSQ-GEEYTBSJSA-N 0.000 abstract 1
- 244000037364 Cinnamomum aromaticum Species 0.000 abstract 1
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 abstract 1
- 235000011511 Diospyros Nutrition 0.000 abstract 1
- 241000218671 Ephedra Species 0.000 abstract 1
- 241000945868 Eulaliopsis Species 0.000 abstract 1
- 241000935235 Fritillaria meleagris Species 0.000 abstract 1
- 244000303040 Glycyrrhiza glabra Species 0.000 abstract 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 abstract 1
- 235000017443 Hedysarum boreale Nutrition 0.000 abstract 1
- 235000007858 Hedysarum occidentale Nutrition 0.000 abstract 1
- 244000302544 Luffa aegyptiaca Species 0.000 abstract 1
- 235000009814 Luffa aegyptiaca Nutrition 0.000 abstract 1
- 240000007078 Peucedanum palustre Species 0.000 abstract 1
- 235000008040 Peucedanum palustre Nutrition 0.000 abstract 1
- 240000006079 Schisandra chinensis Species 0.000 abstract 1
- 244000248021 Vitex negundo Species 0.000 abstract 1
- 235000013427 Vitex negundo var incisa Nutrition 0.000 abstract 1
- 235000014961 Vitex negundo var negundo Nutrition 0.000 abstract 1
- 240000000038 Ziziphus mauritiana Species 0.000 abstract 1
- 235000006545 Ziziphus mauritiana Nutrition 0.000 abstract 1
- 235000008529 Ziziphus vulgaris Nutrition 0.000 abstract 1
- 230000006838 adverse reaction Effects 0.000 abstract 1
- 235000020224 almond Nutrition 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 229910052602 gypsum Inorganic materials 0.000 abstract 1
- 239000010440 gypsum Substances 0.000 abstract 1
- 230000000366 juvenile effect Effects 0.000 abstract 1
- 235000014956 negundo chastetree Nutrition 0.000 abstract 1
- 210000003802 sputum Anatomy 0.000 abstract 1
- 208000024794 sputum Diseases 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 239000003172 expectorant agent Substances 0.000 description 5
- 230000003419 expectorant effect Effects 0.000 description 5
- 206010035664 Pneumonia Diseases 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 208000037656 Respiratory Sounds Diseases 0.000 description 3
- 230000036760 body temperature Effects 0.000 description 3
- 206010067482 No adverse event Diseases 0.000 description 2
- 206010047924 Wheezing Diseases 0.000 description 2
- 238000002555 auscultation Methods 0.000 description 2
- 239000012141 concentrate Substances 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000035876 healing Effects 0.000 description 2
- 231100000957 no side effect Toxicity 0.000 description 2
- 230000000306 recurrent effect Effects 0.000 description 2
- 230000029058 respiratory gaseous exchange Effects 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 208000000059 Dyspnea Diseases 0.000 description 1
- 206010013975 Dyspnoeas Diseases 0.000 description 1
- 241000825107 Hierochloe Species 0.000 description 1
- 235000015466 Hierochloe odorata Nutrition 0.000 description 1
- 208000008454 Hyperhidrosis Diseases 0.000 description 1
- 206010021143 Hypoxia Diseases 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 241001349804 Juncus alpinoarticulatus Species 0.000 description 1
- 206010039101 Rhinorrhoea Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000009534 blood test Methods 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 210000003714 granulocyte Anatomy 0.000 description 1
- 230000037315 hyperhidrosis Effects 0.000 description 1
- 230000007954 hypoxia Effects 0.000 description 1
- 210000000265 leukocyte Anatomy 0.000 description 1
- 208000010753 nasal discharge Diseases 0.000 description 1
- 230000003448 neutrophilic effect Effects 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 230000002685 pulmonary effect Effects 0.000 description 1
- 206010037833 rales Diseases 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000005096 rolling process Methods 0.000 description 1
- 210000005182 tip of the tongue Anatomy 0.000 description 1
- 210000004916 vomit Anatomy 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/17—Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/26—Aristolochiaceae (Birthwort family), e.g. heartleaf
- A61K36/268—Asarum (wild ginger)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/344—Codonopsis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/44—Ebenaceae (Ebony family), e.g. persimmon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/535—Perilla (beefsteak plant)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/79—Schisandraceae (Schisandra family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/85—Verbenaceae (Verbena family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8966—Fritillaria, e.g. checker lily or mission bells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8968—Ophiopogon (Lilyturf)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
本发明公开了一种用于治疗小儿咳喘的中药颗粒,其由以下重量份的原料制成:生麻黄24、生石膏812、川贝711、丝瓜花58、杏仁46、蓑草根69、苏子46、黄芩58、桂枝46、柿叶1015、党参4.56.5、牡荆子914、旋复花46、前胡46、葶苈子13、细辛0.51.5、五味子3.55.5、橘红58、海浮石812、麦冬58、大枣46、甘草46。本发明中药颗粒中各中药之间相互协同作用,具有宣肺定喘、扶正祛邪、益气固表、止咳化痰等功效,对于小儿咳喘具有显著的疗效,治疗周期短,治愈率高,能够根治小儿咳喘,治愈后不容易反复发作,无毒副作用,无不良反应。
Description
技术领域
本发明涉及一种用于治疗小儿咳喘的中药颗粒,属于中药技术领域。
背景技术
小儿咳喘是儿科常见病,小儿乃稚阴稚阳之体,肺常不足,固表御邪功能弱,加之冷暖不知自调,故易为外邪所犯导致感冒、咳嗽等肺系疾病,表现为咳嗽、喘促、甚者喉间痰鸣、气短懒言等。小儿咳喘具有发病急、变化快、易反复的特点。目前市场上用于治疗小儿咳喘的中药制剂繁多,但是大多数存在着疗效不显著,容易反复发作的缺点。
发明内容
本发明的目的在于针对现有技术的不足,提供一种用于治疗小儿咳喘的中药颗粒。该中药颗粒疗效显著,治愈率高,治愈后不容易反复发作,无毒副作用,无不良反应。
为实现上述目的,本发明采用的技术方案如下:
一种用于治疗小儿咳喘的中药颗粒,由以下重量份的原料制成:生麻黄2-4、生石膏8-12、川贝7-11、丝瓜花5-8、杏仁4-6、蓑草根6-9、苏子4-6、黄芩5-8、桂枝4-6、柿叶10-15、党参4.5-6.5、牡荆子9-14、旋复花4-6、前胡4-6、葶苈子1-3、细辛0.5-1.5、五味子3.5-5.5、橘红5-8、海浮石8-12、麦冬5-8、大枣4-6、甘草4-6。
优选地,一种用于治疗小儿咳喘的中药颗粒,由以下重量份的原料制成:生麻黄3、生石膏9、川贝9、丝瓜花6、杏仁5、蓑草根8、苏子5、黄芩6、桂枝5、柿叶12、党参5、牡荆子12、旋复花5、前胡5、葶苈子2、细辛1、五味子5、橘红6、海浮石9、麦冬6、大枣5、甘草5。
一种用于治疗小儿咳喘的中药颗粒的制备方法,包括以下步骤:
(1)取丝瓜花、桂枝、旋复花、细辛、麦冬、甘草混合均匀,加5-7倍量的水,冷浸3-4h后按水蒸气蒸馏法加热提取,回流4-5h,分出挥发油,备用;
(2)将余下原料混合均匀,粉碎,过80-120目筛,加水煎煮提取2次,每次加8-12倍量的水,每次煎煮2-3h,合并煎液,过滤,滤液浓缩至相对密度为1.20-1.25的浸膏;
(3)将步骤(1)制得的挥发油与步骤(2)制得的浸膏混合,再加入适量的适量的蔗糖及糊精,搅拌均匀,制粒,低温干燥,整粒,装袋,即为成品。
本发明的有益效果:
本发明中药颗粒中各中药之间相互协同作用,具有宣肺定喘、扶正祛邪、益气固表、止咳化痰等功效,对于小儿咳喘具有显著的疗效,治疗周期短,治愈率高,能够根治小儿咳喘,治愈后不容易反复发作,无毒副作用,无不良反应。
具体实施方式
实施例1:
一种用于治疗小儿咳喘的中药颗粒,由以下重量(g)的原料制成:生麻黄2、生石膏8、川贝7、丝瓜花5、杏仁4、蓑草根6、苏子4、黄芩5、桂枝4、柿叶10、党参4.5、牡荆子9、旋复花4、前胡4、葶苈子1、细辛0.5、五味子3.5、橘红5、海浮石8、麦冬5、大枣4、甘草4。
一种用于治疗小儿咳喘的中药颗粒的制备方法,包括以下步骤:
(1)取丝瓜花、桂枝、旋复花、细辛、麦冬、甘草混合均匀,加5倍量的水,冷浸3h后按水蒸气蒸馏法加热提取,回流4h,分出挥发油,备用;
(2)将余下原料混合均匀,粉碎,过80目筛,加水煎煮提取2次,每次加8倍量的水,每次煎煮2h,合并煎液,过滤,滤液浓缩至相对密度为1.20的浸膏;
(3)将步骤(1)制得的挥发油与步骤(2)制得的浸膏混合,再加入适量的适量的蔗糖及糊精,搅拌均匀,制粒,低温干燥,整粒,装袋,即为成品。
实施例2
一种用于治疗小儿咳喘的中药颗粒,由以下重量(g)的原料制成:生麻黄3、生石膏9、川贝9、丝瓜花6、杏仁5、蓑草根8、苏子5、黄芩6、桂枝5、柿叶12、党参5、牡荆子12、旋复花5、前胡5、葶苈子2、细辛1、五味子5、橘红6、海浮石9、麦冬6、大枣5、甘草5。
一种用于治疗小儿咳喘的中药颗粒的制备方法,包括以下步骤:
(1)取丝瓜花、桂枝、旋复花、细辛、麦冬、甘草混合均匀,加6倍量的水,冷浸3.5h后按水蒸气蒸馏法加热提取,回流4.5h,分出挥发油,备用;
(2)将余下原料混合均匀,粉碎,过100目筛,加水煎煮提取2次,每次加10倍量的水,每次煎煮2-3h,合并煎液,过滤,滤液浓缩至相对密度为1.22的浸膏;
(3)将步骤(1)制得的挥发油与步骤(2)制得的浸膏混合,再加入适量的适量的蔗糖及糊精,搅拌均匀,制粒,低温干燥,整粒,装袋,即为成品。
实施例3
一种用于治疗小儿咳喘的中药颗粒,由以下重量(g)的原料制成:生麻黄4、生石膏12、川贝11、丝瓜花8、杏仁6、蓑草根9、苏子6、黄芩8、桂枝6、柿叶15、党参6.5、牡荆子14、旋复花6、前胡6、葶苈子3、细辛1.5、五味子5.5、橘红8、海浮石12、麦冬8、大枣6、甘草6。
一种用于治疗小儿咳喘的中药颗粒的制备方法,包括以下步骤:
(1)取丝瓜花、桂枝、旋复花、细辛、麦冬、甘草混合均匀,加7倍量的水,冷浸4h后按水蒸气蒸馏法加热提取,回流5h,分出挥发油,备用;
(2)将余下原料混合均匀,粉碎,过120目筛,加水煎煮提取2次,每次加2倍量的水,每次煎煮3h,合并煎液,过滤,滤液浓缩至相对密度为1.25的浸膏;
(3)将步骤(1)制得的挥发油与步骤(2)制得的浸膏混合,再加入适量的适量的蔗糖及糊精,搅拌均匀,制粒,低温干燥,整粒,装袋,即为成品。
典型病例:
病例1:李某,男,5岁,2012年5月18日初诊。因“咳嗽10天,加重3天”来诊。现症:咳喘,少痰,发热,体温:39.1℃,口渴,舌红少津,脉滑数。肺部听诊有少量痰鸣音,面部轻度缺氧症状。查血常规示:白细胞12.06×109/L,中性粒细胞百分比:81.3%。胸片提示:右肺炎症。西医诊为小儿肺炎。中医诊为小儿咳喘。于是给服本发明中药颗粒,服药1周后,咳喘轻,发热减,体温:37.8℃,继服1周后,咳喘消失,不发热,体温正常,舌转润,病愈。随访1个月未见复发。
病例2:王某,男,3岁,2010年4月8日初诊。1周前受凉之后咳嗽不止,经治未见好转,遂来我处治疗,请会诊。现症:咳喘痰鸣夜甚,有时呕吐,大便溏,次数多,苔白,舌尖稍赤,脉滑。西医诊为小儿肺炎。中医诊为小儿咳喘。于是服本发明中药颗粒,服药5天后,痰减,呕止,大便正常,继服10天后,咳喘消失,痰无,病愈。随访1个月未见复发。
病例3:宁某,女,7岁,2012年5月14日初诊。患儿于初诊前3天发病,症见咳嗽、喘息明显,吐白色泡沫痰、流涕、汗多。体查:舌淡红、苔薄白、脉濡细,听诊双肺呼吸音弱,可闻及广泛哮鸣音。西医诊为小儿肺炎。中医诊为小儿咳喘。于是服本发明中药颗粒,服药8天后,咳喘明显好转,痰量减少,继服7天。
Claims (3)
1.一种用于治疗小儿咳喘的中药颗粒,其特征在于,由以下重量份的原料制成:生麻黄2-4、生石膏8-12、川贝7-11、丝瓜花5-8、杏仁4-6、蓑草根6-9、苏子4-6、黄芩5-8、桂枝4-6、柿叶10-15、党参4.5-6.5、牡荆子9-14、旋复花4-6、前胡4-6、葶苈子1-3、细辛0.5-1.5、五味子3.5-5.5、橘红5-8、海浮石8-12、麦冬5-8、大枣4-6、甘草4-6。
2.根据权利要求1所述的一种用于治疗小儿咳喘的中药颗粒,其特征在于,由以下重量份的原料制成:生麻黄3、生石膏9、川贝9、丝瓜花6、杏仁5、蓑草根8、苏子5、黄芩6、桂枝5、柿叶12、党参5、牡荆子12、旋复花5、前胡5、葶苈子2、细辛1、五味子5、橘红6、海浮石9、麦冬6、大枣5、甘草5。
3.根据权利要求1或2所述的一种用于治疗小儿咳喘的中药颗粒,其特征在于,其制备方法包括以下步骤:
(1)取丝瓜花、桂枝、旋复花、细辛、麦冬、甘草混合均匀,加5-7倍量的水,冷浸3-4h后按水蒸气蒸馏法加热提取,回流4-5h,分出挥发油,备用;
(2)将余下原料混合均匀,粉碎,过80-120目筛,加水煎煮提取2次,每次加8-12倍量的水,每次煎煮2-3h,合并煎液,过滤,滤液浓缩至相对密度为1.20-1.25的浸膏;
(3)将步骤(1)制得的挥发油与步骤(2)制得的浸膏混合,再加入适量的适量的蔗糖及糊精,搅拌均匀,制粒,低温干燥,整粒,装袋,即为成品。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610105317.0A CN105709090A (zh) | 2016-02-25 | 2016-02-25 | 一种用于治疗小儿咳喘的中药颗粒 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610105317.0A CN105709090A (zh) | 2016-02-25 | 2016-02-25 | 一种用于治疗小儿咳喘的中药颗粒 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN105709090A true CN105709090A (zh) | 2016-06-29 |
Family
ID=56157112
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201610105317.0A Pending CN105709090A (zh) | 2016-02-25 | 2016-02-25 | 一种用于治疗小儿咳喘的中药颗粒 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN105709090A (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111067969A (zh) * | 2018-10-22 | 2020-04-28 | 广西小咕噜生物科技有限公司 | 一种治疗小儿咳喘的外用中药药膏 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1193535A (zh) * | 1998-03-21 | 1998-09-23 | 朱殿文 | 止咳胶囊 |
-
2016
- 2016-02-25 CN CN201610105317.0A patent/CN105709090A/zh active Pending
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1193535A (zh) * | 1998-03-21 | 1998-09-23 | 朱殿文 | 止咳胶囊 |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111067969A (zh) * | 2018-10-22 | 2020-04-28 | 广西小咕噜生物科技有限公司 | 一种治疗小儿咳喘的外用中药药膏 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN101766804B (zh) | 一种治疗鼻衄的中药组合物及其制备方法 | |
CN105920085A (zh) | 一种具有减毒功效的组合物及其制备方法和应用 | |
CN101234168B (zh) | 一种复方当归制剂及制备方法和用途 | |
CN101829267B (zh) | 一种治疗肺喘病的中药组合物及其制备方法 | |
CN102119979B (zh) | 口腔溃疡复方制剂 | |
CN102380061A (zh) | 一种祛痰、消痰、止咳的中药组合物及制备方法和应用 | |
CN101411835B (zh) | 一种治疗止咳平喘化祛痰肺气肿支气管炎病的药物 | |
CN105055950A (zh) | 一种治疗复发性口腔溃疡的中药制剂及其制备方法 | |
CN103656122B (zh) | 治疗外感热病的中药及其制备方法 | |
CN103961614A (zh) | 用于治疗呼吸系统疾病的中药组合物及其制备方法和用途 | |
CN101757516A (zh) | 一种治疗小儿过敏性哮喘的中药配方 | |
CN101249255B (zh) | 一种治疗小儿咳嗽的中成药及其制备方法 | |
CN105709090A (zh) | 一种用于治疗小儿咳喘的中药颗粒 | |
CN102698099B (zh) | 一种治疗糖尿病的丸剂 | |
CN107158286B (zh) | 一种用于治疗雾霾致呼吸道损伤诱发症的中药组合物及其制备方法 | |
CN104606600A (zh) | 一种治疗间质性肺病的中药组合物及其制备方法 | |
CN104435644A (zh) | 用于治疗哮喘的中药制剂及其制作方法和应用 | |
CN102671156A (zh) | 一种治疗哮喘的中药汤剂及其制备方法 | |
CN103041143B (zh) | 一种具有去火生津通便的中药组合物及其制备方法 | |
CN114588228B (zh) | 一种治疗2型糖尿病的组合物 | |
CN103055118A (zh) | 一种治疗哮喘的中药 | |
CN102580023A (zh) | 一种治疗脾胃不和、脘腹胀痛的药物 | |
CN106110156A (zh) | 一种用于慢性阻塞性肺疾病的膏方、制备方法及其用途 | |
CN104958430A (zh) | 一种治疗慢性气管炎的中药组合物及其制备方法 | |
CN118750561A (zh) | 一种用于新冠病毒感染恢复期的中药组合物及其制备方法和应用 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
WD01 | Invention patent application deemed withdrawn after publication | ||
WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20160629 |