CN1057004A - A kind of production method of antifungal - Google Patents
A kind of production method of antifungal Download PDFInfo
- Publication number
- CN1057004A CN1057004A CN 90105139 CN90105139A CN1057004A CN 1057004 A CN1057004 A CN 1057004A CN 90105139 CN90105139 CN 90105139 CN 90105139 A CN90105139 A CN 90105139A CN 1057004 A CN1057004 A CN 1057004A
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- CN
- China
- Prior art keywords
- cinnamic aldehyde
- suppository
- prescription
- antifungal
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention provides a kind of production method of antifungal, its technical essential is: (1) selects Cortex Cinnamomi, Cortex cinnamomi japonici (Ramulus Cinnamomi) and Ramulus Cinnamomi for use, (2) extract its active ingredient---cinnamic aldehyde, the prescription of making vein emulsion is: water: 97.5%, cinnamic aldehyde: 1%, solubilizing agent: 1.5%, vein emulsion is used for intravenously administrable.Make the prescription of suppository: cinnamic aldehyde: 1%, lanoline: 0.05-0.1%, water: 0.5%, suppository base: 98.45-98.4%, suppository is used for colpitis mycotica.The present invention can kill mycete effectively, and without any side effects, and cost is low, is fit to band mycotic patient and uses.
Description
The invention belongs to the production method of a kind of production method of medicine, particularly a kind of antifungal.
Broad ectrum antibiotic can kill some common pathogenic bacterias, effectively such as staphylococcus aureus, streptococcus pneumoniae, escherichia coli etc.Except that above-mentioned bacterium is arranged, also have mycete in the patient's body that has, behind the broad ectrum antibiotic that uses a period of time, broad ectrum antibiotic kills common pathogenic bacteria, but it is powerless to mycete, only remaining mycete in the body, and the patient just produces dysbacteriosis.Clinical manifestation is: high fever, use broad ectrum antibiotic more, and just serious more, cause death at last.
The amphotericin B of external import is comparatively ideal antifungal, but because its side effect is too big, and leukocyte, patient feel cold that fever, gastrointestinal reaction are strong such as killing, alopecia etc., and the clinician is difficult to application.It costs an arm and a leg in addition.The domestic kind that does not still substitute this medicine at present.
The production method that the purpose of this invention is to provide a kind of antifungal.
The solution of the present invention is:
1, selects raw material: Cortex Cinnamomi, Cortex cinnamomi japonici (Ramulus Cinnamomi), Ramulus Cinnamomi;
2, extract its active ingredient-cinnamic aldehyde, the method for extraction is:
2.1, use steam distillation;
2.2, separate;
3, make hydrostatic arteries and veins Emulsion or suppository with cinnamic aldehyde
3.1, make the prescription of vein emulsion:
Because cinnamic aldehyde is an oil preparation, very difficult molten with water, so need add solubilizing agent.
Water: 97.5%
Cinnamic aldehyde: 1%
Solubilizing agent: 1.5%
Vein emulsion is used for intravenously administrable.
3.2, make the prescription of suppository:
Cinnamic aldehyde: 1%
Lanoline: 0.05-0.1%
Water: 0.5%
Suppository base: 98.45-98.4%
Suppository is used for colpitis mycotica.
The present invention compared with prior art has following advantage:
1, can kill mycete effectively;
2, without any side effects;
3, cost is lower.
Claims (1)
1, a kind of production method of antifungal is characterized in that:
(1), selects raw material: Cortex Cinnamomi, Cortex cinnamomi japonici (Ramulus Cinnamomi), Ramulus Cinnamomi;
(2), extract its active ingredient-cinnamic aldehyde, the method for extraction is:
(2.1), use steam distillation;
(2.2), separate;
(3), make hydrostatic arteries and veins Emulsion or suppository with cinnamic aldehyde
(3.1), make the prescription of vein emulsion:
Water: 97.5%
Cinnamic aldehyde: 1%
Solubilizing agent: 1.5%
(3.2), make the prescription of suppository:
Cinnamic aldehyde: 1%
Lanoline: 0.05-0.1%
Water: 0.5%
Suppository base: 98.45-98.4%
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 90105139 CN1057004A (en) | 1990-06-06 | 1990-06-06 | A kind of production method of antifungal |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 90105139 CN1057004A (en) | 1990-06-06 | 1990-06-06 | A kind of production method of antifungal |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1057004A true CN1057004A (en) | 1991-12-18 |
Family
ID=4878972
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 90105139 Pending CN1057004A (en) | 1990-06-06 | 1990-06-06 | A kind of production method of antifungal |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1057004A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105726563A (en) * | 2016-02-02 | 2016-07-06 | 广州自远生物科技有限公司 | Effervescent suppository capable of preventing and treating reproductive system diseases of animals and preparation method thereof |
| CN106176916A (en) * | 2016-08-13 | 2016-12-07 | 广州婕熹卡生物科技有限公司 | A kind of vagina balance conditioning liquid |
| CN107412241A (en) * | 2017-09-25 | 2017-12-01 | 陕西中药研究所 | A kind of Syringin pharmaceutical composition and its application in cervicitis is treated |
-
1990
- 1990-06-06 CN CN 90105139 patent/CN1057004A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105726563A (en) * | 2016-02-02 | 2016-07-06 | 广州自远生物科技有限公司 | Effervescent suppository capable of preventing and treating reproductive system diseases of animals and preparation method thereof |
| CN105726563B (en) * | 2016-02-02 | 2019-03-26 | 广州自远生物科技有限公司 | It is a kind of can prophylactic treatment animals' reproduction systemic disease type of effervescent suppository and preparation method thereof |
| CN106176916A (en) * | 2016-08-13 | 2016-12-07 | 广州婕熹卡生物科技有限公司 | A kind of vagina balance conditioning liquid |
| CN107412241A (en) * | 2017-09-25 | 2017-12-01 | 陕西中药研究所 | A kind of Syringin pharmaceutical composition and its application in cervicitis is treated |
| CN107412241B (en) * | 2017-09-25 | 2020-06-12 | 陕西中药研究所 | Syringin pharmaceutical composition and application thereof in treating cervicitis |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C01 | Deemed withdrawal of patent application (patent law 1993) | ||
| WD01 | Invention patent application deemed withdrawn after publication |