CN105688200A - Drug composition for improving animal immunity and resisting viruses and preparing method thereof - Google Patents

Drug composition for improving animal immunity and resisting viruses and preparing method thereof Download PDF

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Publication number
CN105688200A
CN105688200A CN201610120056.XA CN201610120056A CN105688200A CN 105688200 A CN105688200 A CN 105688200A CN 201610120056 A CN201610120056 A CN 201610120056A CN 105688200 A CN105688200 A CN 105688200A
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parts
probiotics
medicinal composition
herba
immunizing power
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CN201610120056.XA
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Chinese (zh)
Inventor
丁常宏
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Anhui Anfengt Animal Medicine Industry Co Ltd
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Anhui Anfengt Animal Medicine Industry Co Ltd
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Priority to CN201610120056.XA priority Critical patent/CN105688200A/en
Publication of CN105688200A publication Critical patent/CN105688200A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • A61K36/195Strobilanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315Isatis, e.g. Dyer's woad
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634Forsythia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/78Saururaceae (Lizard's-tail family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/54Mixtures of enzymes or proenzymes covered by more than a single one of groups A61K38/44 - A61K38/46 or A61K38/51 - A61K38/53
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2068Compounds of unknown constitution, e.g. material from plants or animals

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention relates to a drug composition, in particular to a drug composition for improving animal immunity and resisting viruses and a preparing method thereof. The drug composition is prepared from, by weight, 10-20 parts of radix isatidis, 8-15 parts of radix bupleuri, 5-10 parts of herba houttuyniae, 5-10 parts of herba andrographitis, 5-8 parts of fructus forsythiae, 4-8 parts of probiotics, 1-3 parts of an enzymic preparation and 10-20 parts of a drug binding agent. Radix isatidis has the effect of inhibiting various bacteria, herba houttuyniae has the antibacterial, antiviral, anti-inflammation and diuresis effects and can obviously promote the capacity for staphylococcus aureus phagocytosis of peripheral blood leucocyte in vitro, synthesized houttuyfonate can improve the leukocytic phagocytosis function of a patient with chronic tracheitis, and herba andrographitis has the effects of clearing away heat and toxic materials, cooling blood and diminishing swelling. The drug composition adjusts an animal immune system, improves organism immunity, removes an immune mechanism, enhances disease resistance of an organism, improves sensitivity to a vaccine of the organism, ensures health and stability of animals, and prevents kinds of bacterium and virus infection.

Description

A kind of raising animal immunizing power and antiviral medicinal composition and preparation method thereof
Technical field
The present invention relates to a kind of pharmaceutical composition, be specially a kind of raising animal immunizing power and antiviral medicinal composition and preparation method thereof。
Background technology
Large-scale cultivation factory owing to size of animal is many, equipment imperfection, sloppy management and multiple disease popularity; cause that animal health condition is bad; vulnerable to disease; and life-time service antibiotics adds the drug resistance of virus and antibacterial; human health is had very big hidden danger by the residual of medicine simultaneously, not only plant is caused serious loss but also the treatment of disease is brought certain suffering。
Chinese medicine has the advantages such as little, the noresidue of toxic and side effects as a kind of natural drug, it is used widely in the prevention of Animal diseases, treatment and raising immunity of organisms etc., a kind of medicine (CN201210491111.8) for strengthening animal immunizing power of prior art, comprise the component of following parts by weight: Echinacea 40%-50%, Herba Epimedii 10%-15%, Radix Codonopsis 10%-20%, propolis 20%-30%, Cortex querci dentatae 10%-15%, Radix Glycyrrhizae 10%-15%, Flos Lonicerae 5%-10%, ceftiofur sodium 5%-10%;The present invention can individually be administered orally or as feed additive, and production cost is low, good stability, applicable industrialized production。
Its toxicity of traditional Chinese medicine is low, without follow-up harm, drug residue is low, the advantage such as wide of originating increasingly receives an acclaim, but general technique is more complicated in prior art pharmaceutical composition, effect is undesirable, poor for applicability to animal, it is thus desirable to provide a kind of suitability relatively, preparation technology is simple, can the medicine that improve animal immunizing power of life-time service。
Summary of the invention
In order to overcome the problems referred to above, it is an object of the invention to provide a kind of raising animal immunity and antiviral medicinal composition and preparation method thereof, its preparation technology is simple, satisfactory for result, the suitability of animal is strong, can effectively regulate animal immune system, improve immunity of organisms, release immunologic mechanism, enhancing body resistance against diseases, improve the body sensitivity to vaccine, it is ensured that animal health is stable, it is prevented that various bacteriums infect。
To achieve these goals, the present invention is by the following technical solutions
According to the first aspect of the invention, one is provided to improve animal immunizing power and antiviral medicinal composition, it is prepared from by the raw material of following weight portion: Radix Isatidis 10-20 part, Radix Bupleuri 8-15 part, Herba Houttuyniae 5-10 part, Herba Andrographis 5-10 part, Fructus Forsythiae 5-8 part, probiotics 4-8 part, enzyme preparation 1-3 part, medicine adhesive 10-20 part。
As the preferred forms of the present invention, one improves animal immunity and antiviral medicinal composition, and it is prepared from by the raw material of following weight portion;Radix Isatidis 15 parts, Radix Bupleuri 10 parts, Herba Houttuyniae 8 parts, Herba Andrographis 6 parts, Fructus Forsythiae 6 parts, probiotics 5 parts, enzyme preparation 2 parts, medicine adhesive 15 parts。
Further, described probiotics is one or more mixing in common probiotics, enzyme preparation and protics, product enzyme probiotics, viable bacteria probiotics, modified form probiotics。
Further, described enzyme preparation is one or more mixing in amylase, protease, cellulase, pectase, 1,4 beta-glucanase, phytase。
Further, described medicine adhesive is syrup。
Further, the concentration of described syrup is 50-70%。
According to the second aspect of the invention, it is provided that a kind of preparation method improving animal immunizing power and antiviral medicinal composition, it comprises the steps;
Each raw material is weighed by deal respectively;
Radix Isatidis, Radix Bupleuri, Herba Houttuyniae, Herba Andrographis, Fructus Forsythiae are respectively dried pulverizing;
The Radix Isatidis dried after pulverizing, Radix Bupleuri, Herba Houttuyniae, Herba Andrographis, Fructus Forsythiae mix homogeneously are added in medicament-making device, pours probiotics, enzyme preparation and medicine adhesive film-making agent into and get final product。
The invention has the beneficial effects as follows: various bacteria is also had inhibitory action by the Radix Isatidis in the present invention, Herba Houttuyniae has antibacterial, antiviral, anti-inflammatory, diuresis, the ability of peripheral blood leucocyte phagocytosis staphylococcus aureus can be obviously promoted in vitro, Sodium Houttuyfonate can improve the phagocytic function of chronic tracheitis patient's leukocyte, Herba Andrographis has heat-clearing and toxic substances removing, removing heat from blood detumescence effect;The present invention regulates animal immune system, improves immunity of organisms, releases immunologic mechanism, enhancing body resistance against diseases, improves the body sensitivity to vaccine, it is ensured that animal health is stable, it is prevented that various bacteriums infect。
Detailed description of the invention
It is an object of the invention to provide a kind of raising animal immunity and antiviral medicinal composition and preparation method thereof, its preparation technology is simple, satisfactory for result, the suitability of animal is strong, it is possible to effectively to regulate animal immune system, improve immunity of organisms, release immunologic mechanism, enhancing body resistance against diseases, improve the body sensitivity to vaccine, ensure that animal health is stable, it is prevented that various bacteriums infect。
To achieve these goals, the present invention is by the following technical solutions
According to the first aspect of the invention, one is provided to improve animal immunizing power and antiviral medicinal composition, it is prepared from by the raw material of following weight portion: Radix Isatidis 10-20 part, Radix Bupleuri 8-15 part, Herba Houttuyniae 5-10 part, Herba Andrographis 5-10 part, Fructus Forsythiae 5-8 part, probiotics 4-8 part, enzyme preparation 1-3 part, medicine adhesive 10-20 part。
As the preferred forms of the present invention, one improves animal immunity and antiviral medicinal composition, and it is prepared from by the raw material of following weight portion;Radix Isatidis 15 parts, Radix Bupleuri 10 parts, Herba Houttuyniae 8 parts, Herba Andrographis 6 parts, Fructus Forsythiae 6 parts, probiotics 5 parts, enzyme preparation 2 parts, medicine adhesive 15 parts。
Further, described probiotics is one or more mixing in common probiotics, enzyme preparation and protics, product enzyme probiotics, viable bacteria probiotics, modified form probiotics。
Further, described enzyme preparation is one or more mixing in amylase, protease, cellulase, pectase, 1,4 beta-glucanase, phytase。
Further, described medicine adhesive is syrup。
Further, the concentration of described syrup is 50-70%。
According to the second aspect of the invention, it is provided that a kind of preparation method improving animal immunizing power and antiviral medicinal composition, it comprises the steps;
Each raw material is weighed by deal respectively;
Radix Isatidis, Radix Bupleuri, Herba Houttuyniae, Herba Andrographis, Fructus Forsythiae are respectively dried pulverizing;
The Radix Isatidis dried after pulverizing, Radix Bupleuri, Herba Houttuyniae, Herba Andrographis, Fructus Forsythiae mix homogeneously are added in medicament-making device, pours probiotics, enzyme preparation and medicine adhesive film-making agent into and get final product。
In order to make those skilled in the art be better understood from the technical scheme in the application; below in conjunction with embodiment, technical scheme is clearly and completely described; obviously; described embodiment is only a part of embodiment of the application; based on the embodiment in the application; the every other embodiment that those of ordinary skill in the art obtain under not making creative work premise, all should belong to the scope of the application protection。
Embodiment 1
A kind of raising animal immunity and antiviral medicinal composition, it is prepared from by the raw material of following weight portion;Radix Isatidis 10 parts, Radix Bupleuri 8 parts, Herba Houttuyniae 5 parts, Herba Andrographis 5 parts, Fructus Forsythiae 5 parts, probiotics 4 parts, enzyme preparation 1 part, medicine adhesive 10 parts。
Described probiotics is one or more mixing in common probiotics, enzyme preparation and protics, product enzyme probiotics, viable bacteria probiotics, modified form probiotics。
One or more described medicine adhesives that described enzyme preparation is in amylase, protease, cellulase, pectase, 1,4 beta-glucanase, phytase are syrup。
The concentration of described syrup is 50%。
A kind of preparation method improving animal immunizing power and antiviral medicinal composition, it comprises the steps;
Each raw material is weighed by deal respectively;
Radix Isatidis, Radix Bupleuri, Herba Houttuyniae, Herba Andrographis, Fructus Forsythiae are respectively dried pulverizing;
The Radix Isatidis dried after pulverizing, Radix Bupleuri, Herba Houttuyniae, Herba Andrographis, Fructus Forsythiae mix homogeneously are added in medicament-making device, pours probiotics, enzyme preparation and medicine adhesive film-making agent into and get final product。
Embodiment 2
A kind of raising animal immunity and antiviral medicinal composition, it is prepared from by the raw material of following weight portion;Radix Isatidis 20 parts, Radix Bupleuri 15 parts, Herba Houttuyniae 10 parts, Herba Andrographis 9 parts, Fructus Forsythiae 7 parts, probiotics 6 parts, enzyme preparation 3 parts, medicine adhesive 20 parts。
Described probiotics is one or more mixing in common probiotics, enzyme preparation and protics, product enzyme probiotics, viable bacteria probiotics, modified form probiotics。
One or more described medicine adhesives that described enzyme preparation is in amylase, protease, cellulase, pectase, 1,4 beta-glucanase, phytase are syrup。
The concentration of described syrup is 60%。
A kind of preparation method improving animal immunizing power and antiviral medicinal composition, it comprises the steps;
Each raw material is weighed by deal respectively;
Radix Isatidis, Radix Bupleuri, Herba Houttuyniae, Herba Andrographis, Fructus Forsythiae are respectively dried pulverizing;
The Radix Isatidis dried after pulverizing, Radix Bupleuri, Herba Houttuyniae, Herba Andrographis, Fructus Forsythiae mix homogeneously are added in medicament-making device, pours probiotics, enzyme preparation and medicine adhesive film-making agent into and get final product。
The invention is not restricted to the details of above-mentioned one exemplary embodiment, and when without departing substantially from the spirit of the present invention or basic feature, it is possible to realize the present invention in other specific forms。Therefore, no matter from which point, embodiment all should be regarded as exemplary, and be nonrestrictive, description should be made as a whole by those skilled in the art, and the technical scheme in each embodiment through appropriately combined, can also form other embodiments that it will be appreciated by those skilled in the art that, the scope of the invention rather than described above limits, it is intended that all changes in the implication of the equivalency dropping on claim and scope included in the present invention。

Claims (7)

1. one kind is improved animal immunizing power and antiviral medicinal composition, it is characterized in that, it is prepared from by the raw material of following weight portion: Radix Isatidis 10-20 part, Radix Bupleuri 8-15 part, Herba Houttuyniae 5-10 part, Herba Andrographis 5-10 part, Fructus Forsythiae 5-8 part, probiotics 4-8 part, enzyme preparation 1-3 part, medicine adhesive 10-20 part。
2. a kind of raising animal immunizing power according to claim 1 and antiviral medicinal composition, it is characterised in that it is prepared from by the raw material of following weight portion;Radix Isatidis 15 parts, Radix Bupleuri 10 parts, Herba Houttuyniae 8 parts, Herba Andrographis 6 parts, Fructus Forsythiae 6 parts, probiotics 5 parts, enzyme preparation 2 parts, medicine adhesive 15 parts。
3. a kind of raising animal immunizing power according to claim 1 and antiviral medicinal composition, it is characterized in that, described probiotics is one or more mixing in common probiotics, enzyme preparation and protics, product enzyme probiotics, viable bacteria probiotics, modified form probiotics。
4. a kind of raising animal immunizing power according to claim 1 and antiviral medicinal composition, it is characterised in that described enzyme preparation is one or more mixing in amylase, protease, cellulase, pectase, 1,4 beta-glucanase, phytase。
5. a kind of raising animal immunizing power according to claim 1 and antiviral medicinal composition, it is characterised in that described medicine adhesive is syrup。
6. a kind of raising animal immunizing power according to claim 5 and antiviral medicinal composition, it is characterised in that the concentration of described syrup is 50-70%。
7. the preparation method improving animal immunizing power and antiviral medicinal composition, it is characterised in that it comprises the steps;
Each raw material is weighed by deal respectively;
Radix Isatidis, Radix Bupleuri, Herba Houttuyniae, Herba Andrographis, Fructus Forsythiae are respectively dried pulverizing;
The Radix Isatidis dried after pulverizing, Radix Bupleuri, Herba Houttuyniae, Herba Andrographis, Fructus Forsythiae mix homogeneously are added in medicament-making device, pours probiotics, enzyme preparation and medicine adhesive film-making agent into and get final product。
CN201610120056.XA 2016-03-03 2016-03-03 Drug composition for improving animal immunity and resisting viruses and preparing method thereof Pending CN105688200A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112156175A (en) * 2020-11-09 2021-01-01 柳州市绿威生物科技有限公司 Composition for degrading drug residues in live fish and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101732745A (en) * 2009-12-29 2010-06-16 西安工程大学 Nano medicine antibacterial and antiviral finishing agent as well as preparation method and finishing method thereof
CN104189231A (en) * 2014-08-19 2014-12-10 郑州马基森生物科技有限公司 Traditional Chinese medicine preparation for resisting virus and enhancing immunity and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101732745A (en) * 2009-12-29 2010-06-16 西安工程大学 Nano medicine antibacterial and antiviral finishing agent as well as preparation method and finishing method thereof
CN104189231A (en) * 2014-08-19 2014-12-10 郑州马基森生物科技有限公司 Traditional Chinese medicine preparation for resisting virus and enhancing immunity and preparation method thereof

Non-Patent Citations (2)

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张庆丽 等: "酶制剂与益生素组合作用原理的研究", 《饲料博览》 *
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112156175A (en) * 2020-11-09 2021-01-01 柳州市绿威生物科技有限公司 Composition for degrading drug residues in live fish and preparation method thereof

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Application publication date: 20160622