CN105686811A - Minimally-invasive encephalic multi-parameter detection probe - Google Patents

Minimally-invasive encephalic multi-parameter detection probe Download PDF

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Publication number
CN105686811A
CN105686811A CN201610100812.2A CN201610100812A CN105686811A CN 105686811 A CN105686811 A CN 105686811A CN 201610100812 A CN201610100812 A CN 201610100812A CN 105686811 A CN105686811 A CN 105686811A
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stiff case
optical fiber
parameter detecting
intracranial
detecting probe
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CN201610100812.2A
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CN105686811B (en
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李韪韬
张言
钱诚
钱志余
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Nanjing University of Aeronautics and Astronautics
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Nanjing University of Aeronautics and Astronautics
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/01Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/03Detecting, measuring or recording fluid pressure within the body other than blood pressure, e.g. cerebral pressure; Measuring pressure in body tissues or organs
    • A61B5/031Intracranial pressure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A61B5/14553Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases specially adapted for cerebral tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/1459Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/04Constructional details of apparatus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0247Pressure sensors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0271Thermal or temperature sensors

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Optics & Photonics (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)

Abstract

A minimally-invasive encephalic multi-parameter detection probe comprises a contact probe located at the front end. The contact probe comprises a rigidity shell and a medical rubber hose. A cavity allowing an optical fiber module to penetrate therein is formed inside the rigidity shell. An annular groove is formed in the end of the rigidity shell. The optical fiber module comprises an optical fiber and an annular leather plug fixed to one end of the optical fiber. The end, not sleeved with the annular leather plug, of the optical fiber module penetrates into the front end of the rigidity shell till the annular leather plug completely enters the annular groove to form a completely-sealed front-end contact probe contact. A first notch is formed in the side wall of the rigidity shell. A pressure sensor is arranged inside the first notch. The medical rubber hose is arranged at the rear end of the rigidity shell and used for wrapping a signal line guide pipe and an optical fiber inside the rigidity shell and connected with a rear-end processing module. The minimally-invasive encephalic multi-parameter detection probe is used for monitoring encephalic multi-parameter indexes in real time.

Description

A kind of minimal removed of intracranial parameter detecting probe
Technical field
The invention belongs to Implanted medical system field, particularly relate to a kind of minimal removed of intracranial parameter detecting probe。
Background technology
In Characters of traumatic brain injury (TraumaticBrainInjury, TBI) patient, having 20% can leave sequela, this crowd of people know from experience the medium-term and long-term impact being subject to sequela of life afterwards, and it creates the waste of substantial amounts of manpower, material resources and financial resources。Study carefully its reason wherein damaged to include Falling Injury, have a fist fight and vehicle accident etc.。The frequent secondary of patients with cerebral injury has traumatic brain edema (TraumaticBrainEdema, TBE) or intracranial hematoma, thus intracranial pressure (ICP) can be caused to increase, cerebral blood flow declines, and increases the weight of brain injury and causes patient death。Clinically, the main monitoring index of traumatic brain edema is ICP and CBF。In the Clinics and Practices of traumatic brain edema, problem demanding prompt solution has: lack a kind of effectively multi-parameter monitoring technology;Lack a kind of curative effect evaluation model for individual difference;Lack a kind of curative effect comprehensive assessment factor being associated with pathologic basis。
Intracranial pressure (IntracranialPressure, ICP) is one of principal element affecting cerebral blood flow, and the measurement of intracranial pressure is to confirming or getting rid of increased intracranial pressure, and determines that cerebral perfusion pressure is very necessary, and this also contributes to patients with sevious craniocerebral injury carries out directiveness treatment。Having substantial amounts of evidence support to use monitoring intracranial pressure, ICP monitoring has been developed as an instrument being highly useful, and has become the core to serious cerebral injury patient's Intensive Care Therapy management。
Intracranial temperature (IntracranialTemperature, ICT) and intracranial pressure have certain relatedness, meanwhile, think that the change of ICT is often early than the change of ICP clinically。In Mild Hypothermal Cerebral protection severe traumatic operated patients with head injury, the treatment of ICT is particularly important。
In neurosurgery, local blood oxygen saturation (rSO2) index has great importance for evaluating brain oxygen metabolism and prognosis。By the measurement of brain local blood oxygen saturation, the complication of sacred disease the generation of measurable delayed ischemic neurological deficits can be found in time。
At present, lacking the instrument with ICP/ICT/rSO2 integration test function clinically so that in neurosurgery, doctor adopts subjectivity and experience to judge the situation of patient, cannot scientific and effective guided operation, evaluate therapeutic effect, frequently result in therapeutic effect undesirable。
Meanwhile, in neurosurgery, measure system owing to lacking many kinds of parameters, therefore evaluation methodology is lacked for limited parameter, also without a standardized data acquisition and storage specification。Nationwide, seems neurosurgery amount huge, acquires a series of data, but lacks unified storage standard, it is impossible to carries out analysis and the identification of Future Data。
For this, be badly in need of developing a kind of Data Collective of Parameters instrument at field of neurosurgery, by clinical and underlying diseases sort research and multi-parameters sampling, set up Clinical practice codes and standards, it is achieved effectively the combining and break through of clinical, basic research。
Summary of the invention
It is an object of the invention to according to above-mentioned present situation, it is provided that a kind of minimal removed of intracranial parameter detecting probe, for monitoring intracranial multiparameter index in real time。
For achieving the above object, the present invention adopts the following technical scheme that
A kind of minimal removed of intracranial parameter detecting probe, including:
Being positioned at the contact probe head of front end, described contact probe head includes a stiff case, is provided with mean for the cavity that optic module wears inside described stiff case, and end is provided with annular groove;Optic module includes optical fiber and is fixed on the annular leather plug of optical fiber one end, and one end of the non-collar-shaped leather plug of optic module penetrates from the front end of stiff case, until annular leather plug is completely into, in annular groove, forming the contact probe head contact, front end of complete seal;
The side sidewall of described stiff case offers the first notch, in described first notch, is provided with pressure transducer;
Medical gels flexible pipe, is arranged on the rear end of described stiff case, for wrapping up holding wire conduit within stiff case and optical fiber and connecting the processing module of rear end。
Pre-buried temperature sensor in described stiff case, described temperature sensor is connected with the processing module of rear end by holding wire。
The rear portion of described stiff case is provided with the cavity for grafting medical gels flexible pipe, stiff case is provided with for the second notch for dispensing glue, first one end of this medical gels flexible pipe is interspersed in the cavity of stiff case rear end, fixes with stiff case again through the second notch carries out a glue。
It is provided with airway in described medical gels flexible pipe。
Described temperature sensor is critesistor。
Described optical fiber is made up of the single-mode fiber of two 100 μm, and wherein one connects light source, and another root connects photoelectric detection system。
Described light source adopts dual wavelength。
Described stiff case is length is the titanium alloy shell of 5mm ~ 10mm length。
Described titanium alloy shell is formed in one structure。
Beneficial effects of the present invention:
The first, described front end titanium alloy shell is integrated with pressure transducer, temperature sensor, local blood oxygen saturation optical fiber, it is possible to realize measuring while intracranial multi-physiological-parameter。
The second, described titanium alloy shell housing ensure that internal other chips except pressure transducer are not by the impact of exterior mechanical stress。
3rd, having fluting on described titanium alloy shell, totally three, two of which is positioned at the upper end of housing, a front end being positioned at housing。Being arranged in two of upper end, one is used for placement force sensor, and the pin of chip is physically separated by convenient use medical adhesive, and does not interfere with the mensuration to intracranial pressure, simplifies welding procedure。
4th, the described light source being connected with optical fiber, adopts dual wavelength, and meanwhile, the light of dual wavelength is also collected, conducted to another root optical fiber connecting photoelectric detection system。Optical fiber use the optical superposition of different wave length can be conducted together, and by ripe algorithm and calibration, it is possible to measure the brain local blood oxygen saturation obtaining fibre-optical probe position。
Accompanying drawing explanation
Fig. 1 is the schematic diagram of each ingredient released state of optic module in intracranial multiparameter of the present invention probe。
Fig. 2 is the schematic diagram of the optic module assembled state in intracranial multiparameter of the present invention probe。
Fig. 3 is the schematic diagram remaining module after intracranial multiparameter of the present invention probe detaches optic module。
Fig. 4 is the intracranial multiparameter of the present invention each ingredient of probe, is assembled into the process schematic of complete probe。
Fig. 5 is the complete diagram of intracranial multiparameter of the present invention probe。
Fig. 6 is the sectional view on intracranial multiparameter probe A A direction of the present invention。
Fig. 7 is the structure size schematic diagram of intracranial multiparameter of the present invention probe complete diagram。
Wherein: the double; two optical fiber of 1-and envelope thereof;2-annular leather plug;3-the first notch;4-pressure transducer;5-temperature sensor;6-airway;7-annular groove;8-colloid flexible pipe;9-holding wire and envelope thereof;10-stiff case;11-the second notch。
Detailed description of the invention
By detailed description of the invention with reference to the accompanying drawings, the present invention is described in further detail below。
As depicted in figs. 1 and 2, the present invention adopts double; two optical fiber as the transmission of near infrared light, accepts path。And double; two optical fiber are packaged in its envelope, it is simple to follow-up threading technique。One end of double; two optical fiber and envelope thereof is enclosed within annular leather plug, and is fixed。
As it is shown on figure 3, this figure shows to remove the side view of every other ingredient outside optic module。
As shown in Figure 4, one end of non-for optic module collar-shaped leather plug is penetrated from the front end of titanium alloy shell。
As it is shown in figure 5, continue above-mentioned to penetrate operation, until annular leather plug and annular groove 7 fully in contact with, form the contact probe head contact, front end of complete seal。
Optic module passes through threading technique, contacts with stiff case perfection, forms the probe contacts of the front end sealed。
Pressure transducer 4 is placed in the first notch of stiff case, this grooving processes, effectively avoids owing to the evagination of pressure transducer causes the mechanical damage to intracranial tissue。This pressure transducer adopts the welding procedure of formula of sinking simultaneously, it is possible to the pin of this sensor is physically separated, and relieves the unnecessary safety concerns such as the short circuit that causes due to pin sealing problem。This sensor is connected with the process circuit of rear end by three holding wires, and signal circuit is included in holding wire conduit 9。
Temperature sensor 5 is placed in the inside of titanium alloy shell, and this Sensitive Apparatus follows stiff case contact when being implanted to cerebral tissue, just can intracranial temperature be measured, and the holding wire of this element is the same with pressure transducer, is included in holding wire conduit 9。
Airway 6, after by 11 glue of the second notch, it is easy to cause stiff case inner space and extraneous air isolation, and the effect of this airway 6 is contemplated to avoid the generation of this situation。
Medical gels flexible pipe 8, for wrapping up holding wire conduit 9 and optic module after being positioned at stiff case 10。First this medical gels flexible pipe 8 is interspersed in the rear end of stiff case 10, after a glue operation, it is possible to this medical gels flexible pipe 8 and stiff case 10 are fixed together。
Holding wire conduit 9 mainly wraps up some necessary holding wires, sends it to the process part of rear end。
Stiff case 10, this stiff case 10 is the protection device of all the sensors and optic module, and its hard shell ensure that internal portions is not by the impact of external force。As an optimal technical scheme of the present invention, the material of this stiff case adopts titanium alloy。
As shown in Figure 6, this figure is the A A profile that the present invention forms complete probe, stiff case 10 is positioned at the device within outermost layer user, medical gels flexible pipe 8 is for wrapping up some internal conduits and optical fiber and connecting the processing module of rear end, holding wire conduit 9, optic module, airway 6 is positioned at medical gels inside hose, connect back end processing module, it is ensured that connect with the space of rear end。

Claims (9)

1. a minimal removed of intracranial parameter detecting probe, it is characterised in that including:
Being positioned at the contact probe head of front end, described contact probe head includes a stiff case, is provided with mean for the cavity that optic module wears inside described stiff case, and end is provided with annular groove;Optic module includes optical fiber and is fixed on the annular leather plug of optical fiber one end, and one end of the non-collar-shaped leather plug of optic module penetrates from the front end of stiff case, until annular leather plug is completely into, in annular groove, forming the contact probe head contact, front end of complete seal;
The side sidewall of described stiff case offers the first notch, in described first notch, is provided with pressure transducer;
Medical gels flexible pipe, is arranged on the rear end of described stiff case, for wrapping up holding wire conduit within stiff case and optical fiber and connecting the processing module of rear end。
2. minimal removed of intracranial parameter detecting probe according to claim 1, it is characterised in that pre-buried temperature sensor in described stiff case, described temperature sensor is connected with the processing module of rear end by holding wire。
3. minimal removed of intracranial parameter detecting probe according to claim 1, it is characterized in that, the rear portion of described stiff case is provided with the cavity for grafting medical gels flexible pipe, stiff case is provided with for the second notch for dispensing glue, first one end of this medical gels flexible pipe is interspersed in the cavity of stiff case rear end, fixes with stiff case again through the second notch carries out a glue。
4. minimal removed of intracranial parameter detecting probe according to claim 3, it is characterised in that be provided with airway in described medical gels flexible pipe。
5. minimal removed of intracranial parameter detecting probe according to claim 2, it is characterised in that described temperature sensor is critesistor。
6. minimal removed of intracranial parameter detecting probe according to claim 1, it is characterised in that described optical fiber is made up of the single-mode fiber of two 100 μm, wherein one connects light source, and another root connects photoelectric detection system。
7. minimal removed of intracranial parameter detecting probe according to claim 6, it is characterised in that described light source adopts dual wavelength。
8. minimal removed of intracranial parameter detecting probe according to claim 1, it is characterised in that described stiff case is length is the titanium alloy shell of 5mm ~ 10mm length。
9. minimal removed of intracranial parameter detecting probe according to claim 8, it is characterised in that described titanium alloy shell is formed in one structure。
CN201610100812.2A 2016-02-24 2016-02-24 A kind of minimal removed of intracranial parameter detecting probe Active CN105686811B (en)

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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107126195A (en) * 2017-05-08 2017-09-05 长飞光纤光缆股份有限公司 A kind of insertion type probe
CN107184191A (en) * 2017-06-29 2017-09-22 长飞光纤光缆股份有限公司 A kind of miniature insertion type probe
CN107320068A (en) * 2017-06-12 2017-11-07 长飞光纤光缆股份有限公司 A kind of preparation method of insertion type probe body
CN107582070A (en) * 2017-09-04 2018-01-16 长飞光纤光缆股份有限公司 A kind of insertion type partial pressure of oxygen temperature combined probe
CN107625516A (en) * 2017-09-04 2018-01-26 长飞光纤光缆股份有限公司 A kind of insertion type medical probe of multi-parameter
CN108325089A (en) * 2018-01-03 2018-07-27 南通大学 A kind of tumour laserthermia and multi-parameters real-time monitoring probe
WO2019037071A1 (en) * 2017-08-25 2019-02-28 Cheng Weyland Device and method for feedback and control using optical fibers in catheters
CN109674460A (en) * 2019-02-18 2019-04-26 中国电子科技集团公司第二十六研究所 A kind of the bougie structure and its packaging method of implanted micro sensor
CN113144394A (en) * 2021-05-18 2021-07-23 江苏爱思普医疗科技有限公司 Intracranial parameter detection device
CN113143231A (en) * 2021-04-19 2021-07-23 武汉理工大学 Human body invasive pressure and temperature multi-parameter real-time optical fiber detection method and system

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5987995A (en) * 1997-07-17 1999-11-23 Sentec Corporation Fiber optic pressure catheter
US20020041723A1 (en) * 2000-09-07 2002-04-11 Erlend Ronnekleiv Multi-parameter fiber optic probes
WO2004026128A1 (en) * 2002-09-17 2004-04-01 Diametrics Medical Limited Apparatus and method for monitoring condition of a patient
CN101179986A (en) * 2005-05-25 2008-05-14 劳梅迪奇股份公司 Probe for measuring oxygen content in biological material as well as vessel containing the probe
CN102170827A (en) * 2008-08-06 2011-08-31 卡拉格股份公司 Device for measuring the blood flow of a body tissue
CN102205162A (en) * 2011-06-17 2011-10-05 南京航空航天大学 Drain tube for intracranial pressure monitoring
CN103829936A (en) * 2014-03-18 2014-06-04 中国工程物理研究院流体物理研究所 Optical fiber craniocerebral pressure monitor
CN104352232A (en) * 2014-12-05 2015-02-18 苏州景昱医疗器械有限公司 Intracranial pressure monitoring system
CN104905781A (en) * 2015-02-13 2015-09-16 林昌军 Encephalic physiological parameter collecting device and application
CN105125201A (en) * 2015-09-29 2015-12-09 江苏爱思普医疗科技有限公司 Implantable intracranial pressure monitoring probe

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5987995A (en) * 1997-07-17 1999-11-23 Sentec Corporation Fiber optic pressure catheter
US20020041723A1 (en) * 2000-09-07 2002-04-11 Erlend Ronnekleiv Multi-parameter fiber optic probes
WO2004026128A1 (en) * 2002-09-17 2004-04-01 Diametrics Medical Limited Apparatus and method for monitoring condition of a patient
CN101179986A (en) * 2005-05-25 2008-05-14 劳梅迪奇股份公司 Probe for measuring oxygen content in biological material as well as vessel containing the probe
CN102170827A (en) * 2008-08-06 2011-08-31 卡拉格股份公司 Device for measuring the blood flow of a body tissue
CN102205162A (en) * 2011-06-17 2011-10-05 南京航空航天大学 Drain tube for intracranial pressure monitoring
CN103829936A (en) * 2014-03-18 2014-06-04 中国工程物理研究院流体物理研究所 Optical fiber craniocerebral pressure monitor
CN104352232A (en) * 2014-12-05 2015-02-18 苏州景昱医疗器械有限公司 Intracranial pressure monitoring system
CN104905781A (en) * 2015-02-13 2015-09-16 林昌军 Encephalic physiological parameter collecting device and application
CN105125201A (en) * 2015-09-29 2015-12-09 江苏爱思普医疗科技有限公司 Implantable intracranial pressure monitoring probe

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107126195A (en) * 2017-05-08 2017-09-05 长飞光纤光缆股份有限公司 A kind of insertion type probe
CN107320068A (en) * 2017-06-12 2017-11-07 长飞光纤光缆股份有限公司 A kind of preparation method of insertion type probe body
CN107184191A (en) * 2017-06-29 2017-09-22 长飞光纤光缆股份有限公司 A kind of miniature insertion type probe
WO2019037071A1 (en) * 2017-08-25 2019-02-28 Cheng Weyland Device and method for feedback and control using optical fibers in catheters
CN107582070A (en) * 2017-09-04 2018-01-16 长飞光纤光缆股份有限公司 A kind of insertion type partial pressure of oxygen temperature combined probe
CN107625516A (en) * 2017-09-04 2018-01-26 长飞光纤光缆股份有限公司 A kind of insertion type medical probe of multi-parameter
CN107582070B (en) * 2017-09-04 2020-06-02 长飞光纤光缆股份有限公司 Intervention type oxygen partial pressure-temperature composite probe
CN108325089A (en) * 2018-01-03 2018-07-27 南通大学 A kind of tumour laserthermia and multi-parameters real-time monitoring probe
CN109674460A (en) * 2019-02-18 2019-04-26 中国电子科技集团公司第二十六研究所 A kind of the bougie structure and its packaging method of implanted micro sensor
CN113143231A (en) * 2021-04-19 2021-07-23 武汉理工大学 Human body invasive pressure and temperature multi-parameter real-time optical fiber detection method and system
CN113143231B (en) * 2021-04-19 2023-08-22 武汉理工大学 Human body invasive pressure temperature multi-parameter real-time optical fiber detection method and system
CN113144394A (en) * 2021-05-18 2021-07-23 江苏爱思普医疗科技有限公司 Intracranial parameter detection device

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