CN108814571A - Haemorrhagic shock severity human blood glucose device - Google Patents

Haemorrhagic shock severity human blood glucose device Download PDF

Info

Publication number
CN108814571A
CN108814571A CN201810481846.XA CN201810481846A CN108814571A CN 108814571 A CN108814571 A CN 108814571A CN 201810481846 A CN201810481846 A CN 201810481846A CN 108814571 A CN108814571 A CN 108814571A
Authority
CN
China
Prior art keywords
module
shock
degree
detection module
carbon dioxide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201810481846.XA
Other languages
Chinese (zh)
Inventor
赵鹏
种银保
潘文才
马珂
杨佳庆
肖晶晶
马结实
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Second Affiliated Hospital Army Medical University
Original Assignee
Second Affiliated Hospital Army Medical University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Second Affiliated Hospital Army Medical University filed Critical Second Affiliated Hospital Army Medical University
Priority to CN201810481846.XA priority Critical patent/CN108814571A/en
Publication of CN108814571A publication Critical patent/CN108814571A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/0205Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/02042Determining blood loss or bleeding, e.g. during a surgical procedure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021Measuring pressure in heart or blood vessels
    • A61B5/02108Measuring pressure in heart or blood vessels from analysis of pulse wave characteristics
    • A61B5/02116Measuring pressure in heart or blood vessels from analysis of pulse wave characteristics of pulse wave amplitude
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/08Detecting, measuring or recording devices for evaluating the respiratory organs
    • A61B5/083Measuring rate of metabolism by using breath test, e.g. measuring rate of oxygen consumption
    • A61B5/0836Measuring rate of CO2 production
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/74Details of notification to user or communication with user or patient ; user input means
    • A61B5/746Alarms related to a physiological condition, e.g. details of setting alarm thresholds or avoiding false alarms

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physiology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

The invention discloses a kind of haemorrhagic shock severity human blood glucose devices, including:Including signal processing module, pulse wave detection module, tissue carbon dioxide partial pressure detection module, flesh oxygen saturation detection module, microprocessor module, human-computer interaction module and power module;The signal processing module amplifies pulse wave detection module, tissue carbon dioxide partial pressure detection module and flesh oxygen saturation detection module signal collected, is filtered, and exports after being converted into digital signal;The microprocessor module receives the digital signal from signal processing module, and is updated in shock Degree Model, obtains the shock degree of patient, and issue corresponding control signal to human-computer interaction module based on shock degree;Human-computer interaction module receives the control information from microprocessor module, and carries out numerical value based on the control signal and show and alarm.The present invention can quickly and accurately evaluate shock degree.

Description

Haemorrhagic shock severity human blood glucose device
Technical field
The invention belongs to medicinal detection devices, and in particular to a kind of haemorrhagic shock severity human blood glucose device.
Background technique
Natural calamity, traffic accident and local war take place frequently in current global range, and haemorrhagic shock, which has become, to be caused Dead key factor.It is shown according to epidemiologic data, in some cities in China, wound has become the head of emergency case Position is the main reason for leading to death, wherein haemorrhagic shock died caused by wound account for wound always dead number of cases 10% ~40%;There are about 5,800,000 people to die of all kinds of wounds every year in the whole world, wherein 34%~50% died of wounds occurs after wound In 1h, reason is mostly the shock that blood loss causes.Therefore, quick, accurate evaluation blood loss degree can be instructed in emergency rescue scene Sick and wounded's recovery, has very important significance to forepart intervention.
Currently, clinically generally using monitoring indexes such as blood pressure, heart rate, urine volume, Pi Wenseze and the state of mind to shock Carry out comprehensive descision.Blood pressure is clinical use index the most universal, but initial stage of suffering a shock, due to compensatory vessel retraction, blood pressure can It is able to maintain or close to normally;Increased heart rate is usually one of the early diagnosis index suffered a shock, but heart rate cannot judge blood loss How much;Urine volume is the reflection preferable index of renal perfusion, can reflect recurrent state indirectly, but time-consuming, it is difficult to for before institute.Skin Warm decline, the change of ochrodermia, the state of mind are also not the specific index of haemorrhagic shock, can not be used for blood loss degree Quantitative analysis." the golden index " that artery blood lactate concentration and base deficit (BD) are diagnosed as haemorrhagic shock is extensively by domestic and international expert Approve, but be unable to continuous non-invasive monitoring, for there is certain limitation before institute.
In recent years, for routine clinical Indexs measure not in time, be unable to quantitative analysis, be dfficult to apply to institute before the deficiencies of, Some scholars have carried out correlative study and have proposed several new detection methods.Due to maintaining vitals perfusion after body blood loss Pressure can be such that vessel retraction, secondary organs and tissues oxygenation reduces, while blood is sent to heart and brain, therefore can use Flesh oxygen saturation is perfused to evaluate peripheral tissues to detect shock degree, but validity of this method under Hypovolemia still needs to It is to be validated.Pulse wave amplitude-variation rate (Δ PW) can also be used to noninvasive continuous detection blood loss degree, because Δ PW is to ventricle Preload variation it is very sensitive, the variation of center blood volume can be showed well, but this method is by current non-invasive measurement arteries and veins It fights the restriction of waveform technology, accuracy is not high under the conditions of slight blood loss and massive blood loss.Mucous membrane of mouth CO2Partial pressure also can be noninvasive Continuous detection blood loss degree.If CN 202128446U discloses a kind of " oral mucosa carbon dioxide partial pressure monitoring device ", adopt Use CO2Microelectrode acquires PBUCO2Signal is shown after amplification filtering and A/D conversion, can be used in haemorrhagic shock degree Quantitative analysis and guide liquid resuscitation, but influence of this method vulnerable to external temperature, testing result is easy to produce baseline drift It moves.In addition, R wave-amplitude, cardiac cycle variability, sublingual mucosa PCO2Etc. indexs can be used for emergency rescue scene quantitative detection Shock degree, but these methods because detection cycle is long, the reasons such as inconvenient due to be difficult to promote.
Emergency rescue scene environmental condition is poor, Bing Yuanduo, medical resource are limited, if can not be right within " prime time " Blood loss degree is rapidly and accurately assessed, and determines reasonable recovery scheme in time, and will lead to treatment personnel can not be implemented with Effect recovery, so that On-the-spot resuscitation success rate is not high, late complication and the death rate are higher.Therefore, in emergency rescue scene item Under part, the requirement rapid, accurate, easy to use for becoming shock degree detection device is detected.
Summary of the invention
The object of the present invention is to provide a kind of haemorrhagic shock severity human blood glucose devices, can quickly, accurately comment Estimate the shock degree of patient out.
Haemorrhagic shock severity human blood glucose device of the present invention, including signal processing module, pulse wave Detection module, tissue carbon dioxide divide detection module, flesh oxygen saturation detection module, microprocessor module, human-computer interaction mould Block and power module;
The pulse wave detection module is used to acquire the pulse wave information of patient;
The tissue carbon dioxide partial pressure detection module is used to acquire the tissue carbon dioxide partial pressure information of patient;
The flesh oxygen saturation detection module is used to acquire the flesh oxygen saturation information of patient;
The signal processing module detects pulse wave detection module, tissue carbon dioxide partial pressure detection module and flesh oxygen saturation Module signal collected is amplified, is filtered, and is exported after being converted into digital signal, the signal processing module respectively with Pulse wave detection module, tissue carbon dioxide partial pressure detection module are connected with flesh oxygen saturation detection module;
The microprocessor module receives the digital signal from signal processing module, and is updated in shock Degree Model, obtains Corresponding control signal is issued to human-computer interaction module, the microprocessor mould to the shock degree of patient, and based on shock degree Block is connect with signal processing module;
Human-computer interaction module receive the control information from microprocessor module, and based on the control signal carry out numerical value show with Alarm, the human-computer interaction module are connect with microprocessor module;
Power module is connect with signal processing module, microprocessor module and human-computer interaction module, is each module for power supply.
Further, the shock Degree Model is:
S=a+b*SmO2+c*ΔPW+d*PTCO2
Wherein:
S indicates shock degree;
SmO2Indicate flesh oxygen saturation;
Δ PW indicates pulse wave amplitude-variation rate, Δ PW=(PWmax-PWmin)/[(PWmax+PWmin)/2],
PWmaxAnd PWminIt is illustrated respectively in the peak swing and minimum amplitude of the pulse wave in the same respiratory cycle;
PTCO2Indicate tissue carbon dioxide partial pressure;
A, b, c, d are regression coefficient.
Further, level Four can be divided into using the finally obtained shock degree of shock Degree Model, slight shock, moderate Shock, severe shock and serious shock;
As blood loss degree S<When 5, it is considered as normal;
When blood loss degree S is in 5~15 as slight shock;
It suffers a shock when blood loss degree S is in 15~30 for moderate;
It is severe shock when blood loss degree S is in 30~40;
As blood loss degree S>It is serious shock when 40.
Further, the microprocessor module includes sampling submodule, computational submodule and control submodule;
The sampling submodule timing acquiring is from the pulse wave detection module, tissue carbon dioxide partial pressure detection module and flesh Oxygen saturation detection module data collected, and it is conveyed to the computational submodule, the sampling submodule and computational submodule Connection;
The computational submodule is based on sampling submodule data collected and pulse wave amplitude-variation is obtained by calculation Rate, flesh oxygen saturation, tissue carbon dioxide divide data, enter data into shock Degree Model and obtain shock degree, and It is conveyed to the control submodule, which connect with control submodule;
The control submodule is based on the shock degree and generates corresponding control signal, and exports to the human-computer interaction mould Block, the control submodule are connect with human-computer interaction module.
Further, the flesh oxygen saturation detection module uses near infrared light spectrum sensor, including spectral detector and two Group near infrared light light source;One group of the near infrared light light source is closer apart from spectral detector, and another group farther out, close red to emit Outer light;The spectral detector is for acquiring the reflectance spectrum for carrying out self-organizing.
Further, the pulse wave detection module is pulse wave sensor.
Further, the human-computer interaction module includes display, indicator light, voice module, keyboard and data transmission interface;
For the keyboard for parameter and threshold value to be arranged and is sent to the microprocessor module, the threshold value includes pulse wave vibration The alarm threshold value of width aberration rate, the alarm threshold value of flesh oxygen saturation, tissue carbon dioxide divide the alarm threshold value and shock of data One of alarm threshold value of degree is a variety of;
The display receives the data from the microprocessor module and display, wherein the data of display include pulse wave Waveform and its amplitude-variation rate score, the waveform of flesh oxygen saturation and numerical value, the waveform of tissue carbon dioxide partial pressure and data and One of numerical value of shock degree is a variety of;
The indicator light receives the signal from the microprocessor module and instruction;
The voice module receives the signal from the microprocessor module, after processing output audio signal to loudspeaker, In, the audio signal includes warning message, the pulse wave amplitude that sensor is detached from warning message, shock degree exceeds threshold value Warning message, flesh oxygen saturation of the aberration rate beyond threshold value warning message, tissue carbon dioxide beyond threshold value divide and exceed threshold One of warning message of value is a variety of;
The data transmission interface is for transmitting data between the microprocessor module and peripheral equipment.
The present invention has the following advantages that:
(1) it divides by detection flesh oxygen saturation, pulse waveform amplitude-variation rate and tissue carbon dioxide and establishes shock journey Degree model to carry out rapid evaluation to haemorrhagic shock degree, compares these parameters of simple observation, compensates for respective defect, energy Enough blood losses that is more acurrate, estimating patient more in time;
(2) flesh oxygen saturation detection module, pulse wave detection module and tissue carbon dioxide partial pressure detection module all have it is noninvasive, The advantages of can continuously measuring;
(3) can show detection data (such as:Pulse waveform and its amplitude-variation rate score, flesh oxygen saturation waveform and The waveform and data of numerical value, tissue carbon dioxide partial pressure) and suffer a shock degree and estimation blood loss numerical quantity;
(4) it cannot be only used for emergency rescue scene detection shock degree, it is prior to be it be instructed to recover;
(5) when sensor falls off, it also can be carried out corresponding warning note;
(6) the preceding input alarm threshold value (warning level of alarm threshold value, flesh oxygen saturation including pulse wave amplitude-variation rate is used The alarm threshold value of value, the alarm threshold value of tissue carbon dioxide partial pressure data and degree of suffering a shock), when some parameter is more than setting threshold When value, system carries out corresponding warning note.
Detailed description of the invention
Fig. 1 is structural block diagram of the invention;
Fig. 2 is the structural block diagram of microprocessor module in Fig. 1;
Fig. 3 is the calibration map that tissue carbon dioxide divides one of electrode in detection module in Fig. 1;
Fig. 4 is main flow chart of the invention;
In figure:1, signal processing module, 2, pulse wave detection module, 3, tissue carbon dioxide divide detection module, 4, flesh oxygen it is full With degree detection module, 5, microprocessor module, 5a, sampling submodule, 5b, computational submodule, 5c, control submodule, 6, man-machine Interactive module, 6a, display, 6b, indicator light, 6c, voice module, 6d, keyboard, 6e, data transmission interface, 7, power module.
Specific embodiment
The present invention will be further explained below with reference to the attached drawings.
Haemorrhagic shock severity human blood glucose device as shown in Figure 1, including signal processing module 1, pulse wave Detection module 2, tissue carbon dioxide divide detection module 3, flesh oxygen saturation detection module 4, microprocessor module 5, man-machine friendship Mutual module 6 and power module 7.Wherein:The pulse wave detection module 2 is used to acquire the pulse wave information of patient.The tissue Carbon dioxide partial pressure detection module 3 is used to acquire the tissue carbon dioxide partial pressure information of patient.The flesh oxygen saturation detects mould Block 4 is used to acquire the flesh oxygen saturation information of patient.The signal processing module 1 is to pulse wave detection module 2, tissue titanium dioxide Carbon partial pressure detection module 3 and the signal collected of flesh oxygen saturation detection module 4 are amplified, are filtered, and are converted into counting It is exported after word signal, which divides detection module 3 with pulse wave detection module 2, tissue carbon dioxide respectively It is connected with flesh oxygen saturation detection module 4.The microprocessor module 5 receives the digital signal from signal processing module 1, and It is updated in shock Degree Model, obtains the shock degree of patient, and corresponding control signal is issued to people based on shock degree Machine interactive module 6, the microprocessor module 5 are connect with signal processing module 1.Human-computer interaction module 6, which receives, comes from microprocessor The control information of module 5, and numerical value is carried out based on the control signal and is shown and alarm, the human-computer interaction module 6 and microprocessor Module 5 connects.Power module 7 is connect with signal processing module 1, microprocessor module 5 and human-computer interaction module 6, is each module Power supply.In the present embodiment, charged lithium cells are can be used in power module, and directly connect with AC 220V.
In the present embodiment, the shock Degree Model is:
S=a+b*SmO2+c*ΔPW+d*PTCO2
Wherein:S indicates shock degree;SmO2Indicate flesh oxygen saturation;Δ PW indicates pulse wave amplitude-variation rate, Δ PW= PWmax-PWmin/[PWmax+PWmin/ 2], PWmaxAnd PWminIt is illustrated respectively in the maximum vibration of the pulse wave in the same respiratory cycle Width and minimum amplitude;PTCO2Indicate tissue carbon dioxide partial pressure;A, b, c, d are regression coefficient.
In the present embodiment, shock degree can be divided into level Four, slight shock, moderate shock, severe shock and serious shock;Its In:As blood loss degree S<When 5, it is considered as normal;When blood loss degree S is in 5~15 as slight shock;When blood loss degree S is in 15 ~30 suffer a shock for moderate;It is severe shock when blood loss degree S is in 30~40;As blood loss degree S>It is serious shock when 40.
Each module is described in detail below:
One, pulse wave detection module
1, pulse wave detection module 2 is pulse wave sensor, for acquiring pulse wave signal.Pulse wave detects mould in the present embodiment Block 2 uses a kind of photo-electric reflection type analog sensor PulseSensor for pulses measure.It detects the basic of pulse wave Principle is to cause light transmittance difference in vascular pulsation using tissue to carry out pulses measure.Pulse wave sensor is by light source It is formed with photoelectric transformer two parts, light source is generally used to the selective certain wavelength of oxygen in arterial blood and hemoglobin The light emitting diode of (500nm~700nm).When light beam penetrates human peripheral blood vessel, since the variation of arteriopalmus hyperemia volume is led It causes the light transmittance of this Shu Guang to change, the light reflected through tissue is received by photoelectric transformer at this time, is changed into telecommunications Number and amplified and exported.In use, pulse wave sensor is worn on finger or ear-lobe etc., can will be adopted by conducting wire connection The analog signal transmission collected is used to be converted to digital signal to single-chip microcontroller, then by can be obtained by respective counts after simple computation Value.2 supply voltage of pulse wave detection module requires 3.3V, output signal 0~3.3V of size, and operating ambient temperature requires -40 DEG C ~85 DEG C.
2, pulse wave aberration rate testing principle
Pulse wave aberration rate Δ PW is calculated with following formula:
Δ PW=PWmax-PWmin/[PWmax+PWmin/2] (1)
Wherein, PWmaxAnd PWminRespectively represent the peak swing and minimum amplitude of the pulse wave in the same respiratory cycle, pulse The amplitude height of wave is obtained by measuring the vertical range of trough to the following wave crest of each pulse wave.
3, pulse wave aberration rate detection method
In use, pulse wave sensor is worn on finger or ear-lobe etc., connected by conducting wire by collected analog signal The A/D conversion module for being transferred to single-chip microcontroller carries out analog-to-digital conversion, then Δ PW can be obtained by formula calculating.
Key procedure is as follows:
Two, tissue carbon dioxide divides detection module
1, tissue carbon dioxide partial pressure detection module 3 is tissue carbon dioxide partial pressure sensor, including support member and is fixed on CO thereon2Microelectrode and thermocouple probe.Wherein, CO2Microelectrode is for acquiring tissue carbon dioxide voltage division signal (this implementation In example, the position of detection is sublingual or oral mucosa).
It being illustrated for acquiring mucous membrane of mouth below, thermocouple probe is used to acquire the temperature signal of mucous membrane of mouth, For temperature-compensating.Wherein, CO2Sensor uses the immersion CO of Microelectrodes2Microelectrode, the electrode belong to Stow-Severinghaus type CO2Gas sensing electrode is selected by pH glass electrode, Ag-AgCl reference electrode with hydrophobic-gas The plastic tube of selecting property film (polytetrafluoroethylene film) forms.
Before experiment, 5%, 10% and 15% CO is utilized2Calibrating gas (the big wound in Shanghai), is demarcated at 25 DEG C, benefit After being fitted with MATLAB software (VR9.0), the wherein calibration curve of some electrode, referring to Fig. 3.
According to calibration curve, CO can be obtained2Concentration calculation formula:
Y=161.6e0.114x (2)
Wherein, y indicates CO2Concentration, x indicate electrode voltage output valve.Influence in view of Temperature changing to microelectrode, it is also necessary to Measurement result is modified.
CO2After sensor measures, output voltage signal is amplified through millivolt adapter, is filtered;Miniature heat Thermocouple probe is used to measure the temperature of mucous membrane of mouth, is connect by Wheatstone bridge formula circuit with filtering and amplifying circuit, output voltage Signal.CO2The output signal of sensor and micro thermocouple probe carries out AD sampling using the A/D conversion module of single-chip microcontroller and (adopts Sample set of frequency is 20Hz), then data substitution formula is calculated, finally obtains CO2Concentration.
Three, flesh oxygen saturation detection module
In the present embodiment, the flesh oxygen saturation detection module 4 uses near infrared light spectrum sensor, including spectral detector and two Group near infrared light light source;One group of the near infrared light light source is closer apart from spectral detector, and another group farther out, close red to emit Outer light;The spectral detector is for acquiring the reflectance spectrum for carrying out self-organizing.
Four, human-computer interaction module
The human-computer interaction module 6 includes display 6a, indicator light 6b, voice module 6c, keyboard 6d and data transmission interface 6e。
For the keyboard 6d for parameter and threshold value to be arranged and is sent to the microprocessor module 5, the threshold value includes arteries and veins Fight the alarm threshold value of amplitude of wave form aberration rate, the alarm threshold value of flesh oxygen saturation, tissue carbon dioxide partial pressure data warning level One of alarm threshold value of value and shock degree is a variety of.In the present embodiment, the threshold value includes pulse wave amplitude-variation The alarm threshold value of rate, the alarm threshold value of flesh oxygen saturation, the alarm threshold value of tissue carbon dioxide partial pressure data and degree of suffering a shock Alarm threshold value.
The display 6a receives the data from the microprocessor module 5 and display, wherein the data of display include Pulse waveform and its amplitude-variation rate score, the waveform of flesh oxygen saturation and numerical value, tissue carbon dioxide partial pressure waveform and One of numerical value of data and shock degree is a variety of.In the present embodiment, the data of display include pulse waveform and its vibration The different rate score of amplitude variation, the waveform of flesh oxygen saturation and numerical value, the waveform of tissue carbon dioxide partial pressure and data and degree of suffering a shock Numerical value.
The indicator light 6b receives the signal from the microprocessor module 5 and instruction.
The voice module 6c receives the signal from the microprocessor module 5, and output audio signal is to raising after processing Sound device, wherein the audio signal includes that sensor disengaging warning message (i.e. when a certain sensor is detached from, send out by system Warning message out), shock degree beyond threshold value warning message (i.e. when suffer a shock degree beyond setting shock degree threshold value when, System alert, in the present embodiment, default is shock degree 15), pulse wave amplitude-variation rate exceed the report of threshold value Warning information (i.e. when pulse waveform and its amplitude-variation rate score exceed preset pulse wave amplitude-variation rate threshold value, is System issue warning note), flesh oxygen saturation beyond threshold value warning message, tissue carbon dioxide partial pressure exceed threshold value alarm signal One of breath is a variety of.In the present embodiment, the audio signal includes that sensor is detached from warning message, shock degree beyond threshold Warning message, flesh oxygen saturation alarm signal beyond threshold value of the warning message, pulse wave amplitude-variation rate of value beyond threshold value Breath, tissue carbon dioxide partial pressure exceed the warning message of threshold value.
The data transmission interface 6e is for transmitting data between the microprocessor module 5 and peripheral equipment.
Five, microprocessor module
As shown in Fig. 2, the microprocessor module 5 includes sampling submodule 5a, computational submodule 5b and control submodule 5c;Institute Sampling submodule 5a timing acquiring is stated from the pulse wave detection module 2, tissue carbon dioxide partial pressure detection module 3 and flesh oxygen The data collected of saturation degree detection module 4, and it is conveyed to the computational submodule 5b, the sampling submodule 5a and calculating submodule Block 5b connection.The computational submodule 5b is based on sampling submodule 5a data collected and pulse wave is obtained by calculation Amplitude-variation rate, flesh oxygen saturation, tissue carbon dioxide divide data, enter data into shock Degree Model and are suffered a shock Degree, and it is conveyed to the control submodule 5c, computational submodule 5b is connect with control submodule 5c.The control submodule 5c is based on the shock degree and generates corresponding control signal, and exports to the human-computer interaction module 6, control submodule 5c It is connect with human-computer interaction module 6.
In the present embodiment, in C8051F series monolithic of the microprocessor module 5 using the release of U.S. Cygnal company A small-sized single-chip microcontroller C8051f320.It has the microcontroller completely compatible with MCS-51 kernel and instruction set, in addition to having Common analog component and its are also integrated in data acquistion and control system except the digital peripherals component of standard 8051, in piece Its digital peripherals and functional component.Internal flash storage may be implemented in System Programming, can both make program storage or make non- Volatile data storage.JTAG artificial circuit provides the in-circuit emulation of full speed in piece, is not take up user resources in piece.It supports disconnected The debug commands such as point, single step, point of observation, operation and stopping, and support memory and register check and modification.
As shown in figure 4, the present apparatus use process is as follows:Device is switched on and enters initialization, completes to system initialization Afterwards, be arranged parameters alarm threshold value (such as:The alarm of the alarm threshold value, flesh oxygen saturation of pulse wave amplitude-variation rate The alarm threshold value of threshold value, the alarm threshold value of tissue carbon dioxide partial pressure data and degree of suffering a shock);And input the information (ratio of patient Such as:Name, age, gender, height and weight).Pulse wave is acquired by pulse wave detection module 2, by organizing carbon dioxide It divides detection module 3 and acquires tissue carbon dioxide partial pressure data, flesh oxygen saturation detection module 4 is utilized to acquire flesh oxygen saturation degree According to.Judge sensor (such as:Electrode) whether fall off, if sensor has fallen off, carry out audio alert prompt;If sensor is not It falls off, then calculates shock degree S, and show the numerical value and estimation blood loss of shock degree;While it by shock degree S and presetting Shock degree threshold value be compared, if shock degree S exceed shock degree threshold value, carry out audio alert prompt.
In the present embodiment, additionally it is possible to the amplitude of wave form aberration rate that will fight in real time, flesh oxygen saturation and tissue carbon dioxide point Pressure is compared with corresponding threshold value respectively, if a certain parameter has exceeded corresponding threshold value, system can also issue audio alert and mention Show.

Claims (7)

1. a kind of haemorrhagic shock severity human blood glucose device, it is characterised in that:Including signal processing module(1), arteries and veins It fights wave detection module(2), tissue carbon dioxide divide detection module(3), flesh oxygen saturation detection module(4), microprocessor mould Block(5), human-computer interaction module(6)And power module(7);
The pulse wave detection module(2)For acquiring the pulse wave information of patient;
The tissue carbon dioxide divides detection module(3)Tissue carbon dioxide for acquiring patient divides information;
The flesh oxygen saturation detection module(4)For acquiring the flesh oxygen saturation information of patient;
The signal processing module(1)To pulse wave detection module(2), tissue carbon dioxide divide detection module(3)With flesh oxygen Saturation degree detection module(4)Signal collected is amplified, is filtered, and is exported after being converted into digital signal, the signal Processing module(1)Respectively with pulse wave detection module(2), tissue carbon dioxide divide detection module(3)It is examined with flesh oxygen saturation Survey module(4)Connection;
The microprocessor module(5)It receives and comes from signal processing module(1)Digital signal, and be updated to shock Degree Model In, the shock degree of patient is obtained, and corresponding control signal is issued to human-computer interaction module based on shock degree(6), this is micro- Processor module(5)With signal processing module(1)Connection;
Human-computer interaction module(6)It receives and comes from microprocessor module(5)Control information, and based on the control signal carry out numerical value Display and alarm, the human-computer interaction module(6)With microprocessor module(5)Connection;
Power module(7)With signal processing module(1), microprocessor module(5)And human-computer interaction module(6)Connection is each mould Block power supply.
2. haemorrhagic shock severity human blood glucose device according to claim 1, it is characterised in that:The shock Degree Model is:
S=a+b* SmO2+c*ΔPW+d* PTCO2
Wherein:
S indicates shock degree;
SmO2Indicate flesh oxygen saturation;
Δ PW expression pulse wave amplitude-variation rate, Δ PW=(PWmax-PWmin)/[(PWmax+PWmin)/ 2],
PWmaxAnd PWminIt is illustrated respectively in the peak swing and minimum amplitude of the pulse wave in the same respiratory cycle;
PTCO2Indicate tissue carbon dioxide partial pressure;
A, b, c, d are regression coefficient.
3. haemorrhagic shock severity human blood glucose device according to claim 2, it is characterised in that:Using described The shock finally obtained shock degree of Degree Model can be divided into level Four, slight shock, moderate shock, severe shock and serious stop Gram;
As blood loss degree S<When 5, it is considered as normal;
When blood loss degree S is in 5 ~ 15 as slight shock;
It suffers a shock when blood loss degree S is in 15 ~ 30 for moderate;
It is severe shock when blood loss degree S is in 30 ~ 40;
As blood loss degree S>It is serious shock when 40.
4. haemorrhagic shock severity human blood glucose device according to any one of claims 1 to 3, it is characterised in that: The microprocessor module(5)Including sampling submodule(5a), computational submodule(5b)And control submodule(5c);
The sampling submodule(5a)Timing acquiring comes from the pulse wave detection module(2), tissue carbon dioxide partial pressure detection Module(3)With flesh oxygen saturation detection module(4)Data collected, and it is conveyed to the computational submodule(5b), the sampling Submodule(5a)With computational submodule(5b)Connection;
The computational submodule(5b)Based on the sampling submodule(5a)Pulse wave is obtained by calculation in data collected Amplitude-variation rate, flesh oxygen saturation, tissue carbon dioxide divide data, enter data into shock Degree Model and are suffered a shock Degree, and it is conveyed to the control submodule(5c), the computational submodule(5b)With control submodule(5c)Connection;
The control submodule(5c)Corresponding control signal is generated based on the shock degree, and is exported to the human-computer interaction Module(6), the control submodule(5c)With human-computer interaction module(6)Connection.
5. haemorrhagic shock severity human blood glucose device according to any one of claims 1 to 3, it is characterised in that: The flesh oxygen saturation detection module(4)Using near infrared light spectrum sensor, including spectral detector and two groups of near infrared light light Source;One group of the near infrared light light source is closer apart from spectral detector, and another group farther out, to emit near infrared light;The light Spectrum detector is for acquiring the reflectance spectrum for carrying out self-organizing.
6. haemorrhagic shock severity human blood glucose device according to any one of claims 1 to 3, it is characterised in that: The pulse wave detection module(2)For pulse wave sensor.
7. haemorrhagic shock severity human blood glucose device according to claim 3, it is characterised in that:It is described man-machine Interactive module(6)Including display(6a), indicator light(6b), voice module(6c), keyboard(6d)And data transmission interface(6e);
The keyboard(6d)For parameter and threshold value to be arranged and is sent to the microprocessor module(5), the threshold value includes arteries and veins Fight the alarm threshold value of amplitude of wave form aberration rate, the alarm threshold value of flesh oxygen saturation, tissue carbon dioxide partial pressure data warning level One of alarm threshold value of value and shock degree is a variety of;
The display(6a)It receives and comes from the microprocessor module(5)Data and display, wherein the data of display include Pulse waveform and its amplitude-variation rate score, the waveform of flesh oxygen saturation and numerical value, tissue carbon dioxide partial pressure waveform and One of numerical value of data and shock degree is a variety of;
The indicator light(6b)It receives and comes from the microprocessor module(5)Signal and instruction;
The voice module(6c)It receives and comes from the microprocessor module(5)Signal, output audio signal is to raising after processing Sound device, wherein the audio signal includes warning message, the pulse that sensor is detached from warning message, shock degree exceeds threshold value Warning message, flesh oxygen saturation of the amplitude of wave form aberration rate beyond threshold value warning message, tissue carbon dioxide point beyond threshold value One of the warning message of pressure beyond threshold value is a variety of;
The data transmission interface(6e)For the microprocessor module(5)Data are transmitted between peripheral equipment.
CN201810481846.XA 2018-05-18 2018-05-18 Haemorrhagic shock severity human blood glucose device Pending CN108814571A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810481846.XA CN108814571A (en) 2018-05-18 2018-05-18 Haemorrhagic shock severity human blood glucose device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201810481846.XA CN108814571A (en) 2018-05-18 2018-05-18 Haemorrhagic shock severity human blood glucose device

Publications (1)

Publication Number Publication Date
CN108814571A true CN108814571A (en) 2018-11-16

Family

ID=64147850

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201810481846.XA Pending CN108814571A (en) 2018-05-18 2018-05-18 Haemorrhagic shock severity human blood glucose device

Country Status (1)

Country Link
CN (1) CN108814571A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111135445A (en) * 2020-01-17 2020-05-12 吉林大学第一医院 Device is protected with real-time temperature monitoring to severe patient of hemorrhagic shock

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111135445A (en) * 2020-01-17 2020-05-12 吉林大学第一医院 Device is protected with real-time temperature monitoring to severe patient of hemorrhagic shock

Similar Documents

Publication Publication Date Title
WO2019161608A1 (en) Multi-parameter monitoring data analysis method and multi-parameter monitoring system
CN201542615U (en) Portable network vital sign monitoring instrument
CN106901705A (en) A kind of unaware human Body Physiology Multi-parameter harvester and acquisition method and application
CN105708431A (en) Real-time blood pressure measuring device and measuring method
CN102525651A (en) Portable medical monitoring system for new arrival suffering from major disease
CN110897631B (en) Real-time pregnancy monitoring device and method
CN204971245U (en) Human many parameter monitoring of vital sign system
Al-Aubidy et al. Real-time patient health monitoring and alarming using wireless-sensor-network
CN104739394A (en) Portable human body physiological signal monitoring and alarming system
Xie et al. Development of wearable pulse oximeter based on internet of things and signal processing techniques
CN109009019A (en) Multi-parameter physiological detector
CN103610454A (en) Blood pressure measurement method and system
CN106073735A (en) A kind of integrated circuit structure for continuous detecting human blood-pressure
KR20180065039A (en) Smart phone ubiquitous healthcare diagnosis system using vital integrated communication module
CN113143226A (en) Multi-physiological parameter fusion method and system
CN108814571A (en) Haemorrhagic shock severity human blood glucose device
TW201306795A (en) Multi-channel physiological signal measurement device for ear and method thereof
TW201325553A (en) Oximeter and pulse monitoring system with irregular heartbeat calculating and displaying functions
CN111513693A (en) Miniature comprehensive monitor for human vital signs
CN202104912U (en) Early condition intelligent recognition monitor
CN103519791A (en) System and method for collecting human body temperature
CN208447576U (en) Multi-parameter detector
CN203898280U (en) Human health condition monitoring device
CN115633948A (en) Portable vital sign monitoring devices
CN211187185U (en) Combined type physiological detection device

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
WD01 Invention patent application deemed withdrawn after publication
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20181116