CN105683393B - 多核苷酸分析 - Google Patents

多核苷酸分析 Download PDF

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Publication number
CN105683393B
CN105683393B CN201480044219.XA CN201480044219A CN105683393B CN 105683393 B CN105683393 B CN 105683393B CN 201480044219 A CN201480044219 A CN 201480044219A CN 105683393 B CN105683393 B CN 105683393B
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polynucleotide
pattern
sequence
specific
labeling
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CN105683393A (zh
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曹涵
亚历克斯·R·海斯蒂
恩内斯特·特兹-特森·拉姆
泽利科·扎库拉
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Bionano Genomics Inc
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Bionano Genomics Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/705—Specific hybridization probes for herpetoviridae, e.g. herpes simplex, varicella zoster
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/6893—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for protozoa
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/10—Sequence alignment; Homology search
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Evolutionary Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medical Informatics (AREA)
  • Theoretical Computer Science (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN201480044219.XA 2013-06-10 2014-06-09 多核苷酸分析 Active CN105683393B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361833378P 2013-06-10 2013-06-10
US61/833,378 2013-06-10
PCT/US2014/041568 WO2014200926A2 (en) 2013-06-10 2014-06-09 Analysis of polynucleotides

Publications (2)

Publication Number Publication Date
CN105683393A CN105683393A (zh) 2016-06-15
CN105683393B true CN105683393B (zh) 2020-08-07

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US (1) US12442052B2 (enExample)
EP (1) EP3008216A4 (enExample)
JP (1) JP6556705B2 (enExample)
CN (1) CN105683393B (enExample)
WO (1) WO2014200926A2 (enExample)

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FR3049090B1 (fr) * 2016-03-21 2021-06-25 Sebastien Jean Serge Dupont Dispositif d'authentification biometrique adaptatif par echographie, photographies en lumiere visible de contraste et infrarouge, sans divulgation, a travers un reseau informatique decentralise
EP3885448B1 (en) * 2016-09-02 2023-03-22 New England Biolabs, Inc. Analysis of chromatin using a nicking enzyme
CN108728430B (zh) * 2017-04-21 2022-04-05 胤安国际（辽宁）基因科技股份有限公司 一种制备含有多个重复单元dna长探针的方法
US11505826B2 (en) * 2017-07-12 2022-11-22 Agilent Technologies, Inc. Sequencing method for genomic rearrangement detection
WO2019178273A1 (en) * 2018-03-13 2019-09-19 Guardant Health, Inc. Methods for the non-invasive detection and monitoring of therapeutic nucleic acid constructs
CN111378647A (zh) * 2018-12-27 2020-07-07 北京贝瑞和康生物技术有限公司 一种快速制备单分子光学图谱标记文库的方法和试剂盒
WO2021260644A1 (en) * 2020-06-25 2021-12-30 Perseus Biomics Kit and methods for characterizing a virus in a sample
WO2024145268A2 (en) 2022-12-25 2024-07-04 Bionano Genomics, Inc. Optical genome mapping cartridges
EP4639178A1 (en) 2022-12-25 2025-10-29 Bionano Genomics, Inc. Optical genome mapping system
EP4639177A1 (en) 2022-12-25 2025-10-29 Bionano Genomics, Inc. Instrumentation of optical genome mapping systems

Citations (1)

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Publication number Priority date Publication date Assignee Title
CN103502468A (zh) * 2009-10-21 2014-01-08 生物纳米基因公司 用于单分子全基因组分析的方法和相关装置

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EP2537925A1 (en) * 2005-08-04 2012-12-26 New England Biolabs, Inc. Novel restriction endonucleases, DNA encoding these endonucleases, and methods for identifying new endonucleases with the same or varied specificity
EP2207901B1 (en) * 2007-10-17 2018-07-25 Wisconsin Alumni Research Foundation Methods of whole genome analysis
US8524878B1 (en) * 2008-02-19 2013-09-03 Opgen, Inc. Methods of identifying an organism
US8628919B2 (en) * 2008-06-30 2014-01-14 Bionano Genomics, Inc. Methods and devices for single-molecule whole genome analysis
US20100330557A1 (en) 2009-06-30 2010-12-30 Zohar Yakhini Genomic coordinate system
US20120283955A1 (en) * 2011-02-28 2012-11-08 Pathogenetix, Inc. Methods for data manipulation relating to polymer linear analysis

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
CN103502468A (zh) * 2009-10-21 2014-01-08 生物纳米基因公司 用于单分子全基因组分析的方法和相关装置

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
Genome mapping on nanochannel arrays for structural variation analysis and sequence assembly;Ernest T Lam等;《Nature Biotechonology》;20120715;第30卷(第8期);第771-777页 *
Identification and mapping of a common proviral integration site Fli-1in erythroleukemia cells induced by Friend murine leukemia virus;Yaacov Ben-David等;《Proceedings of the National Academy of Sciences of the United States of America》;19900228;第87卷(第4期);第1332-1336页 *
Multicolor Super-Resolution DNA Imaging for Genetic Analysis;Murat Baday等;《Nano Letters》;20120614;第12卷;第3861-3866页 *
Single molecule linear analysis of DNA in nano-channel labeled with sequence specific fluorescent probes;Somes K. Das等;《Nucleic Acids Research》;20100810;第38卷(第18期);第e117页 *

Also Published As

Publication number Publication date
EP3008216A4 (en) 2017-02-22
US20160201147A1 (en) 2016-07-14
WO2014200926A3 (en) 2015-03-12
CN105683393A (zh) 2016-06-15
JP6556705B2 (ja) 2019-08-07
US12442052B2 (en) 2025-10-14
EP3008216A2 (en) 2016-04-20
JP2016523533A (ja) 2016-08-12
WO2014200926A2 (en) 2014-12-18

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