CN105683146B - 通过环丙基乙烯基前体与质子酸的反应制备高烯丙型化合物 - Google Patents

通过环丙基乙烯基前体与质子酸的反应制备高烯丙型化合物 Download PDF

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CN105683146B
CN105683146B CN201480058481.XA CN201480058481A CN105683146B CN 105683146 B CN105683146 B CN 105683146B CN 201480058481 A CN201480058481 A CN 201480058481A CN 105683146 B CN105683146 B CN 105683146B
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isomer
acid
mnu
homoallylic
mmol
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CN105683146A (zh
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F·施罗德
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Givaudan SA
Amyris Inc
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Amyris Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/07—Preparation of halogenated hydrocarbons by addition of hydrogen halides
    • C07C17/08—Preparation of halogenated hydrocarbons by addition of hydrogen halides to unsaturated hydrocarbons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/09—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis
    • C07C29/095—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis of esters of organic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/09—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis
    • C07C29/12—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis of esters of mineral acids
    • C07C29/124—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis of esters of mineral acids of halides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09—Geometrical isomers

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  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CN201480058481.XA 2013-10-25 2014-10-24 通过环丙基乙烯基前体与质子酸的反应制备高烯丙型化合物 Active CN105683146B (zh)

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Application Number Priority Date Filing Date Title
GB1318894.1 2013-10-25
GBGB1318894.1A GB201318894D0 (en) 2013-10-25 2013-10-25 Improvements in or relating to organic compounds
PCT/EP2014/072891 WO2015059293A1 (en) 2013-10-25 2014-10-24 Preparation of homoallylic compounds by reaction of cyclopropylvinyl precursors with bronstedt acids

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CN105683146A CN105683146A (zh) 2016-06-15
CN105683146B true CN105683146B (zh) 2018-02-06

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US (1) US9884803B2 (enExample)
EP (1) EP3060542B1 (enExample)
JP (1) JP6733992B2 (enExample)
CN (1) CN105683146B (enExample)
BR (1) BR112016008895B1 (enExample)
ES (1) ES2669213T3 (enExample)
GB (1) GB201318894D0 (enExample)
IL (1) IL244928B (enExample)
MX (1) MX379420B (enExample)
SG (1) SG11201602722YA (enExample)
WO (1) WO2015059293A1 (enExample)

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GB201507170D0 (en) 2015-04-24 2015-06-10 Givaudan Sa Process
GB201507207D0 (en) 2015-04-24 2015-06-10 Givaudan Sa Enzymes and applications thereof
GB201516396D0 (en) 2015-09-16 2015-10-28 Givaudan Sa Improvements in or relating to organic compounds
GB201618090D0 (en) * 2016-10-26 2016-12-07 Givaudan Sa Product
EP3476822A1 (en) 2017-10-31 2019-05-01 Givaudan SA Process of making organic compounds
CN107828709B (zh) * 2017-11-09 2021-06-25 天津大学 异源合成龙涎香醇的重组大肠杆菌及其构建方法
CN110963877B (zh) * 2019-12-18 2022-10-04 河北旭阳能源有限公司 1-氯-1-氯乙酰基环丙烷的制备方法
GB202010072D0 (en) * 2020-07-01 2020-08-12 Givaudan Sa Enzyme-mediated process
GB202020331D0 (en) 2020-12-22 2021-02-03 Givaudan Sa Process of making organic compounds

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102449158A (zh) * 2009-06-05 2012-05-09 巴斯夫欧洲公司 龙涎呋喃的生物催化产生
US20130273619A1 (en) * 2012-04-16 2013-10-17 Basf Se Process for the Preparation of (3E, 7E)-Homofarnesol

Family Cites Families (1)

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Publication number Priority date Publication date Assignee Title
US5854405A (en) 1997-11-13 1998-12-29 Aerojet-General Corporation Continuous process for diazomethane from an n-methyl-n-nitrosoamine and from methylurea through n-methyl-n-nitrosourea

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102449158A (zh) * 2009-06-05 2012-05-09 巴斯夫欧洲公司 龙涎呋喃的生物催化产生
US20130273619A1 (en) * 2012-04-16 2013-10-17 Basf Se Process for the Preparation of (3E, 7E)-Homofarnesol

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Ring-Opening Reactions of Methylenecyclopropanes Promoted by Metal Halides;Bo Xu,et al.;《Organic Letters》;20030405;第5卷(第9期);1415-1418 *

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BR112016008895A8 (pt) 2020-03-24
US9884803B2 (en) 2018-02-06
CN105683146A (zh) 2016-06-15
IL244928A0 (en) 2016-05-31
WO2015059293A1 (en) 2015-04-30
MX379420B (es) 2025-03-10
JP2016540036A (ja) 2016-12-22
IL244928B (en) 2019-09-26
JP6733992B2 (ja) 2020-08-05
US20160251298A1 (en) 2016-09-01
GB201318894D0 (en) 2013-12-11
EP3060542A1 (en) 2016-08-31
MX2016005052A (es) 2016-08-17
SG11201602722YA (en) 2016-05-30
BR112016008895B1 (pt) 2021-11-03
EP3060542B1 (en) 2018-02-21
ES2669213T3 (es) 2018-05-24

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