CN105663590A

CN105663590A - Traditional Chinese medicine for treating vitreous hemorrhage opacity and preparation thereof

Info

Publication number: CN105663590A
Application number: CN201610090731.9A
Authority: CN
Inventors: 葛建杰; 王沫学
Original assignee: Individual
Current assignee: Individual
Priority date: 2016-02-06
Filing date: 2016-02-06
Publication date: 2016-06-15

Abstract

The invention relates to a traditional Chinese medicine for treating the vitreous hemorrhage opacity. The traditional Chinese medicine is characterized by being prepared from, by weight, 6-9 parts of radix bupleuri, 4-6 parts of Aizoon Stonecrop Herb, 4-6 parts of Arabic cowry shell, 6-9 parts of concha haliotidis, 2-4 parts of feather cockscomb seeds, 6-9 parts of common selfheal fruit-spike, 6-8 parts of witloof, 6-9 parts of pyrrosia leaf, 4-6 parts of hedgehog hide, 6-9 parts of selaginella tamariscina, 6-9 parts of Japanese inula herb, 4-6 parts of radix rosae laevigatae, 6-9 parts of rhizoma smilacis glabrae, 4-6 parts of herba hyperici japonici and 4-6 parts of liquorice roots. The traditional Chinese medicine has the advantages of clearing liver fire, improving eyesight, reducing swelling and resolving mass, eliminating stagnant blood and stopping bleeding, soothing nerves for eliminate vitreous hemorrhage opacity, and restoring eyesight.

Description

A kind of Chinese medicine and preparation thereof treating vitreous hemorrhage opacity

Technical field

The present invention relates to a kind of Chinese medicine and the preparation thereof for the treatment of vitreous hemorrhage opacity.

It is well known that normal glass body is a kind of special mucus glue sample tissue, transparent gel state, itself is without blood vessel and nervous tissue, and its metabolism is extremely slow, and its nutrition and metabolism is that the diffusion by adjacent tissue completes. Vitreous opacity refers to occur opaque body in vitreum. It is not a kind of independent illness in eye, but one of common sign of clinical ophthalmology. The topmost symptom of vitreous opacity is exactly have shadow at the moment, and form differs, and the impact of eyesight is different because of muddy position and degree. Common cause have the elderly's vitreous degeneration, retina or a uveal tract hemorrhage enter vitreum, high myopia, congenital remain in vitreum embryonic cell or tissue, ocular injury, intraocular foreign body retain, parasite and tumour etc. Patient answers early diagnosis, early treatment, prevents inflammation, hemorrhage etc. causes vitreous opacity, strengthens safe drumbeating education, reduces ocular injury. The symptom of vitreous hemorrhage opacity: muscae genetic vision, visual disorder. Conventional eye drop or operative treatment at present, but easily repeatedly, make troubles to patient's life.

Summary of the invention

Useful effect of Chinese medicine of the present invention is: clearing liver-fire, bright order, mass dissipating and swelling eliminating, loose stasis of blood hemostasis, calms the nerves to release vitreous opacity, recover eyesight.

Clearing heat and detoxicating, activating collaterals and eliminating stagnation, promoting regeneration of tissue for astringency. Clinical upper often give diagnosis and treatment based on an overall analysis of the illness and the patient's condition according to different disease type.

Technical problem to be solved by this invention is the deficiency in order to overcome in technology, it is provided that a kind of good effect, the course for the treatment of are short, and remission rate height, cost is low, a kind of Chinese medicine and the preparation thereof treating vitreous hemorrhage opacity having no side effect.

In order to above-mentioned purpose, a kind of Chinese medicine treating vitreous hemorrhage opacity, it is characterised in that its raw material medicines in portions by weight is as follows: radix bupleuri 6-9 part, white aizoon stonecrop 4-6 part, Concha Erosariae seu Cypraeae 4-6 part, Sea-ear Shell 6-9 part, Semen Celosiae 2-4 part, Spica Prunellae 6-9 part, witloof 6-8 part, pyrrosia lingua 6-9 part, Hedgehog Skin 4-6 part, Selaginella tamariscina 6-9 part, Inula lineariifolia Turcz. 6-9 part, Root of Cherokee Rose 4-6 part, Rhizome of Glabrous Greenbrier 6-9 part, Herba Hyperici Japonici 4-6 part, Radix Glycyrrhizae 4-6 part.

Auxiliary material: add dextrin in the scope that regulation allows.

Preparation method: first shelled by Semen Celosiae, extracts volatile oil for subsequent use; Concha Erosariae seu Cypraeae, Sea-ear Shell are ground fine powder; To get Concha Erosariae seu Cypraeae again, Sea-ear Shell adds water, and to get distillate for subsequent use in distillation;Fresh witloof is squeezed the juice for subsequent use; In radix bupleuri, white aizoon stonecrop, Spica Prunellae, pyrrosia lingua, Selaginella tamariscina, Inula lineariifolia Turcz., Root of Cherokee Rose, Rhizome of Glabrous Greenbrier, Herba Hyperici Japonici, Radix Glycyrrhizae the are added 6 times multi-function extractor of 65% ethanol, reflux 1 hour, get filtrate to filter, reclaim using up of ethanol, obtain alcohol extract for subsequent use; Again by residue boiling 2 hours, filtrate filters and mixes with above-mentioned volatile oil, distillate, fresh witloof juice, alcohol extract, stirs even, adds dextrin by 1: 1, concentrates the clear cream to relative density 1.18-1.25 (60 DEG C), to obtain final product.

Effect of Chinese medicine of the present invention: radix bupleuri taste is pungent, bitter, cold nature. Return liver, courage, lung channel. Effect: evacuate and bring down a fever, dispersing the stagnated live-QI to relieve the stagnation of QI, rises and lifts yang-energy. For cold, fever, alternate attacks of chills and fever, distending pain in the chest and hypochondrium, menoxenia, uterine prolapse, prolapse of the anus. The acid sweet, micro-of white aizoon stonecrop taste, property is put down. Effect: the thoughts of returning home, Liver Channel. Effect: loose stasis of blood hemostasis, calms the nerves. For spitting blood, spitting of blood, bleeding from five sense organs or subcutaneous tissue, purpura, uterine bleeding, traumatic hemorrhage, palpitation and insomnia, have the fidgets. Concha Erosariae seu Cypraeae taste is salty, and property is put down. Return liver, the heart channel of Hang-Shaoyin. Effect: calming the liver, tranquillizing the mind by relieving convulsion, improving acuity of vision and removing nebula. For dizziness due to hyperactivity of liver-YANG, palpitation with fear insomnia, cataract. Sea-ear Shell taste is salty, cold in nature. Return Liver Channel. Effect; Calming the liver, clear liver and improve vision. Dizzy for having a headache, cataract, blurring of vision, glaucoma night blindness. Semen Celosiae bitter, cold nature. Return Liver Channel. Effect; Clearing liver-fire, improving acuity of vision and removing nebula. For the hot hot eyes of liver, the raw screen film of order, blurring of vision, dizziness due to liver-fire. Spica Prunellae taste is pungent, bitter, cold in nature. Return liver, gallbladder channel. Effect; Clearing liver-fire, bright order, mass dissipating and swelling eliminating. For conjunctival congestion with pain and swelling of the eye, order pearl nyctalgia, has a headache dizzy, scrofula, goiter and tumor, acute mastitis, breast addiction, distending pain of the breast. Witloof mildly bitter flavor, salty, cool in nature. Return liver, courage, stomach warp. Effect; Clearing liver profit courage, stomach strengthening and digestion promoting, promotes the production of body fluid to quench thirst, inducing diuresis to remove edema. For jaundice due to damp-heat, stomachache food is few, and interior heat is quenched one's thirst, and oedema urine is few. Pyrrosia lingua taste is micro-sweet, bitter, cold nature. Return lung, bladder warp. Effect; Inducing diuresis for treating stranguria syndrome, removing heat from the lung to relieve cough, cooling blood for hemostasis. Drenching for heat, blood drenches, urolithiasis, and urine is obstructed, drenches the puckery pain of drop, dyspnea and cough due to lung-heat, spits blood, bleeding from five sense organs or subcutaneous tissue, hematuria, uterine bleeding. Hedgehog Skin bitter, puckery, property is put down. Return kidney, stomach, large intestine channel. Effect; Controlling nocturnal emission with astringent drugs contracting urine, astringing to arrest bleeding, blood-activating analgetic. For emission and spermatorrhea, enuresis frequent micturition, hemorrhoid of having blood in stool blood, gastral cavilty shouting pain, food is told in gastric disorder causing nausea. Selaginella tamariscina taste is pungent, and property is put down. Return liver, the heart channel of Hang-Shaoyin. Effect; Promoting blood circulation to restore menstrual flow. For through closing dysmenorrhoea, lump in the abdomen lump in the abdomen, injury from falling down. Selaginella tamariscina charcoal removing blood stasis and hemostasis, for spitting blood, uterine bleeding, has blood in stool, prolapse of the anus. Inula lineariifolia Turcz. bitter, pungent, salty, warm in nature. Return lung, large intestine channel. Effect; Gas falls, dissolving phlegm, row water. For catching cold, phlegm and retained fluid stores knot, coughs that to breathe heavily phlegm many, and chest diaphragm ruffian is full. Root of Cherokee Rose bitter, puckery, cool in nature. Return spleen, liver, kidney channel. Effect; Astringing to arrest bleeding, clearing heat and promoting diuresis, subduing swelling and detoxicating. Rhizome of Glabrous Greenbrier taste is sweet, light, and property is put down. Return liver, stomach warp. Effect; Removing toxic substances, dehumidifying, easing joint movement. For the limbs contraction caused by syphilis and mercury poisoning, arthralgia and myalgia; Damp and hot pouring is turbid, and under band, carbuncle swells, scrofula, mange. Herba Hyperici Japonici bitter, pungent, property is put down. Return liver, gallbladder channel. Effect; Eliminating damp-heat, dissipating blood stasis for subsidence of swelling. For jaundice due to damp-heat, sore furuncle carbuncle swells, wound. Radix Glycyrrhizae taste is sweet, and property is put down. The thoughts of returning home, lung, spleen, stomach warp.Effect; Invigorate the spleen and benefit qi, clearing heat and detoxicating, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription. Above medicine matches, and brings out the best in each other.

The present invention follows the prescription principle of the traditional Chinese medical science, water decoction use, through clinical application for many years checking, always has efficiency 96.76%, and curative ratio 87.09%, has no side effect.

Embodiment

Below in conjunction with embodiment, the invention will be further described:

Embodiment 1: plant the Chinese medicine treating vitreous hemorrhage opacity, it is characterised in that its raw material medicines in portions by weight is as follows: radix bupleuri 6-9 part, white aizoon stonecrop 4-6 part, Concha Erosariae seu Cypraeae 4-6 part, Sea-ear Shell 6-9 part, Semen Celosiae 2-4 part, Spica Prunellae 6-9 part, witloof 6-8 part, pyrrosia lingua 6-9 part, Hedgehog Skin 4-6 part, Selaginella tamariscina 6-9 part, Inula lineariifolia Turcz. 6-9 part, Root of Cherokee Rose 4-6 part, Rhizome of Glabrous Greenbrier 6-9 part, Herba Hyperici Japonici 4-6 part, Radix Glycyrrhizae 4-6 part. Preparation method is the same.

Embodiment 2: plant the Chinese medicine treating vitreous hemorrhage opacity, it is characterised in that its raw material medicines in portions by weight is as follows: radix bupleuri 9 parts, white aizoon stonecrop 6 parts, Concha Erosariae seu Cypraeae 4 parts, Sea-ear Shell 6 parts, Semen Celosiae 4 parts, Spica Prunellae 9 parts, witloof 6 parts, pyrrosia lingua 9 parts, Hedgehog Skin 4 parts, Selaginella tamariscina 6 parts, Inula lineariifolia Turcz. 6 parts, Root of Cherokee Rose 4 parts, Rhizome of Glabrous Greenbrier 6 parts, Herba Hyperici Japonici 4 parts, 6 parts, Radix Glycyrrhizae. Preparation method, with embodiment 1, obtains cream clearly, is distributed into bag, and every bag containing 10g.

Clinical efficacy is summed up:

One, physical data: we are extensive in clinical application for many years, treatment patient 62 example, the age, average 52 years old, curative effect was frequently good at 20～78 years old.

Two, Case definition: common cause has: the elderly's vitreous degeneration, retina or uveal tract hemorrhage enter vitreum, high myopia, congenital remain in vitreum embryonic cell or tissue, ocular injury, intraocular foreign body retain, parasite and tumour etc. Clinical manifestation: 1. muscae genetic vision waves, shadow is waved with eye movement. 2. visual deterioration in various degree. checking: under ophthalmoscope or slit lamp, 90D spectroscopy is visible, the dregs of dirt shape in vitreum, strip, the different shape such as netted or cotton-shaped waves with eye movement. 2. muddy severe patient can not see eyeground or reflective without redness. 3.B type ultrasound investigation can auxiliary diagnosis.

Three, method of administration: qinghuo reagent every day 2 times, each 10g., early, evening for oral administration, within 10th, be 1 course for the treatment of.

Four, curative effect judging standard

Cure: clinical symptom disappearance.

Take a turn for the better: symptom alleviates.

Invalid: clinical symptom is unchanged or increases the weight of.

Five, result for the treatment of: the present invention is for many years in clinical application, and treatment 62 example patient, cures 54 examples, account for 87.09%, and take a turn for the better 6 examples, accounts for 9.67%; Invalid 2 examples account for 3.22%; Efficiency is always had to plant the Chinese medicine treating vitreous hemorrhage opacity, it is characterised in that its raw material medicines in portions by weight is as follows: radix bupleuri 6-9 part, white aizoon stonecrop 4-6 part, Concha Erosariae seu Cypraeae 4-6 part, Sea-ear Shell 6-9 part, Semen Celosiae 2-4 part, Spica Prunellae 6-9 part, witloof 6-8 part, pyrrosia lingua 6-9 part, Hedgehog Skin 4-6 part, Selaginella tamariscina 6-9 part, Inula lineariifolia Turcz. 6-9 part, Root of Cherokee Rose 4-6 part, Rhizome of Glabrous Greenbrier 6-9 part, Herba Hyperici Japonici 4-6 part, Radix Glycyrrhizae 4-6 part.

Six, model case

1, X is opened, man, 55 years old. In October, 2012 goes to a doctor. Main suit's ocular injury 1 week, visual deterioration is serious, occurs that shadow is waved with eye movement, blurred vision. lose improvement in local hospital treatment. Have a medical check-up: muddy severe patient can not see eyeground or reflective without redness; 90D spectroscopy is visible: dirt shape in vitreum, strip, netted or cotton-shaped patient require to take Chinese medicine 2 of the present invention course for the treatment of, get better and turn, continue to take for 1 course for the treatment of, clinical symptom completely dissolve, follow up a case by regular visits to half a year and do not recur again.

2, Song X, man, 78 years old, in August, 2014 went to a doctor, and main suit diagnoses vitreous degeneration in locality, often occurs that shadow is waved with eye movement. Have a medical check-up: retina or uveal tract hemorrhage enter vitreum, visual deterioration, muddy severe patient can not see eyeground or reflective without redness. Patient requires to take Chinese medicine of the present invention 20 days, clinical symptom completely dissolve, follows up a case by regular visits to and do not recur again after half a year.

3, in X, female, 31 years old, in May, 2015 went to a doctor. Main suit's high myopia, visual deterioration. give western medicine through doctor, poor effect in local commune hospital. Have a medical check-up: left scleroma is softened, form yellow purulence bubble at eyelashes root. Laboratory examination: under ophthalmoscope or slit lamp, 90D spectroscopy is visible, the dregs of dirt shape in vitreum, strip, the different shape such as netted or cotton-shaped waves with eye movement. . Patient requires to take 10 doses, Chinese medicine of the present invention, clinical symptom completely dissolve, follows up a case by regular visits to and do not recur again after 1 year.

Claims

1. treat the Chinese medicine of vitreous hemorrhage opacity for one kind, it is characterised in that its raw material medicines in portions by weight is as follows: radix bupleuri 6-9 part, white aizoon stonecrop 4-6 part, Concha Erosariae seu Cypraeae 4-6 part, Sea-ear Shell 6-9 part, Semen Celosiae 2-4 part, Spica Prunellae 6-9 part, witloof 6-8 part, pyrrosia lingua 6-9 part, Hedgehog Skin 4-6 part, Selaginella tamariscina 6-9 part, Inula lineariifolia Turcz. 6-9 part, Root of Cherokee Rose 4-6 part, Rhizome of Glabrous Greenbrier 6-9 part, Herba Hyperici Japonici 4-6 part, Radix Glycyrrhizae 4-6 part.

Auxiliary material: add dextrin in the scope that regulation allows.

2. according to claim 1 Chinese medicinal preparation method treating vitreous hemorrhage opacity, it is characterized in that first being shelled by Semen Celosiae, extract volatile oil for subsequent use; Concha Erosariae seu Cypraeae, Sea-ear Shell are ground fine powder; To get Concha Erosariae seu Cypraeae again, Sea-ear Shell adds water, and to get distillate for subsequent use in distillation; Fresh witloof is squeezed the juice for subsequent use; In radix bupleuri, white aizoon stonecrop, Spica Prunellae, pyrrosia lingua, Selaginella tamariscina, Inula lineariifolia Turcz., Root of Cherokee Rose, Rhizome of Glabrous Greenbrier, Herba Hyperici Japonici, Radix Glycyrrhizae the are added 6 times multi-function extractor of 65% ethanol, reflux 1 hour, get filtrate to filter, reclaim using up of ethanol, obtain alcohol extract for subsequent use; Again by residue boiling 2 hours, filtrate filters and mixes with above-mentioned volatile oil, distillate, fresh witloof juice, alcohol extract, stirs even, adds dextrin by 1: 1, concentrates the clear cream to relative density 1.18-1.25 (60 DEG C), to obtain final product.