CN105663270A - Drug for treating eczema - Google Patents

Drug for treating eczema Download PDF

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Publication number
CN105663270A
CN105663270A CN201610140938.2A CN201610140938A CN105663270A CN 105663270 A CN105663270 A CN 105663270A CN 201610140938 A CN201610140938 A CN 201610140938A CN 105663270 A CN105663270 A CN 105663270A
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CN
China
Prior art keywords
parts
medicine
eczema
metronidazole
vitamin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610140938.2A
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Chinese (zh)
Inventor
毕云鹏
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Zheng Qi Bio Tech Ltd Jinan
Original Assignee
Zheng Qi Bio Tech Ltd Jinan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Zheng Qi Bio Tech Ltd Jinan filed Critical Zheng Qi Bio Tech Ltd Jinan
Priority to CN201610140938.2A priority Critical patent/CN105663270A/en
Publication of CN105663270A publication Critical patent/CN105663270A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4415Pyridoxine, i.e. Vitamin B6
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634Forsythia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention relates to a drug, in particular to a drug for treating eczema.The drug is prepared from, by weight, 10-20 parts of fructus forsythiae, 5-10 parts of honeysuckle flowers, 10-20 parts of perfoliote knotweed herb, 1-3 parts of herb of artemisia annua Linn., 5-8 parts of vitamin B6, 3-5 parts of radix angelica sinensis and 1-2 parts of metronidazole.According to the drug for treating the eczema, metronidazole, vitamin B6 and the traditional Chinese herbs are adopted to be prepared into tablets, the drug is orally taken, the eczema caused by various reasons can be effectively treated, use is convenient, the cost is low, and no side effect exists.

Description

A kind of medicine treating eczema
Technical field
The present invention relates to a kind of medicine, be specifically related to a kind of medicine treating eczema.
Background technology
Eczema is a kind of inflammatory dermatoses that common are epidermis that multiple internal and external factor causes and high dermis, is mainly in the positions such as head, extremity song side and perineum, often in general or symmetry distribution. Treatment eczema mostly adopts and wipes outside the medicine containing 17-hydroxy-11-dehydrocorticosterone at present, although there being certain curative effect, but side effect is relatively big, and once after drug withdrawal, the easy recurrent exerbation of eczema is more serious even than before, so long period or heavy dose of external corticosteroids medicine in a short time should be avoided as far as possible.
Summary of the invention
For solving various difficult problems for above-mentioned treatment pneumoconiosis, the invention provides the medicine of a kind of new treatment eczema, adopt metronidazole, vitamin B6And Chinese traditional herbs makes tablet, adopt oral method, it is possible to the eczema that effective treatment a variety of causes causes, easy to use, cheap and be free from side effects.
A kind of medicine treating eczema of the present invention, in parts by weight, its proportioning is each component of this medicine: Fructus Forsythiae 10-20 part, Flos Lonicerae 5-10 part, Herba Polygoni cymosi 10-20 part, Herba Artemisiae annuae 1-3 part, vitamin B65-8 part, Radix Angelicae Sinensis 3-5 part, metronidazole 1-2 part.
Its concrete processing method is: by Fructus Forsythiae, Flos Lonicerae, Herba Polygoni cymosi, Herba Artemisiae annuae, Radix Angelicae Sinensis according to prescription ratio mix homogeneously, is jointly ground into coarser powder, sieves, and by the thick medicamental pulverata after sieving and vitamin B6, metronidazole be mixed and made into tablet, every 30 is one bottle, is packaged as finished product.
Instructions of taking: adopt oral, each take a piece of, every day twice. Take 5 days 10 days be a course for the treatment of. Generally take and can have remarkable result 2 courses for the treatment of.
Studying for a long period of time and manufacturing experimently through inventor, finally found that when the proportioning of above-mentioned Chinese medicine is following values, and the effect for the treatment of is best, and the weight portion of this proportioning is: Fructus Forsythiae 15 parts, Flos Lonicerae 10 parts, Herba Polygoni cymosi 15 parts, Herba Artemisiae annuae 3 parts, vitamin B68 parts, Radix Angelicae Sinensis 4 parts, metronidazole 1 part.
The primary efficacy of main component of the present invention is:
Fructus Forsythiae: bitter in the mouth, cold nature. Heat-clearing and toxic substances removing, mass dissipating and swelling eliminating.
Flos Lonicerae: property is sweet, cold fragrance, clearing away heat with drugs sweet in flavor and cold in nature and do not injure one's stomach, fragrance thoroughly reach and can eliminating evil Flos Lonicerae can dispelling wind-heat, also kind blood-cleaning detoxifying, for various febrile diseases.
Radix Angelicae Sinensis: blood circulation promoting and enriching, for all diseases of blood deficiency.
Herba Polygoni cymosi: sour in the mouth, cool in nature, clearing heat and expelling damp, pain relieving of drawing out pus by applying a plaster to the affected part.
Herba Artemisiae annuae: acrid in the mouth, bitter, cool in nature, antipyretic damp eliminating, wind dispelling pain relieving.
Vitamin B6Precious activity can be liked by enhancing body epidermis, improve the metabolic process of skin, mucosa, and have the effect of suppression histamine.
Metronidazole: mucocutaneous disease is had significant curative effect.
The medicine for the treatment of eczema provided by the present invention, is part Western medicine and parts of traditional Chinese medicine due to what adopt, Synergistic and cheap, it is possible to promote the use of on a large scale; Owing to adopting the Chinese crude drug of pure natural, decrease side effects of pharmaceutical drugs; Adopt the packaging of tablet, both facilitated daily taking, be convenient for carrying again can medication at any time, alleviate patient's misery when falling ill, be suitable for each phase patient of various age brackets and take; Treatment time is short, instant effect.
Detailed description of the invention
Embodiment 1
A kind of medicine treating eczema, in parts by weight, its proportioning is each component of this medicine: Fructus Forsythiae 15 parts, Flos Lonicerae 10 parts, Herba Polygoni cymosi 15 parts, Herba Artemisiae annuae 3 parts, vitamin B68 parts, Radix Angelicae Sinensis 4 parts, metronidazole 1 part.
By Fructus Forsythiae, Flos Lonicerae, Herba Polygoni cymosi, Herba Artemisiae annuae, Radix Angelicae Sinensis according to prescription ratio mix homogeneously, jointly it is ground into coarser powder, crosses 100 mesh sieves, and by the thick medicamental pulverata after sieving and vitamin B6, metronidazole be mixed and made into tablet, every 30 is one bottle, is packaged as finished product.
In above-mentioned prescription, every part is 1g.
Embodiment 2
A kind of medicine treating eczema, in parts by weight, its proportioning is each component of this medicine: Fructus Forsythiae 10 parts, Flos Lonicerae 10 parts, Herba Polygoni cymosi 15 parts, Herba Artemisiae annuae 3 parts, vitamin B66 parts, Radix Angelicae Sinensis 5 parts, metronidazole 1 part.
By Fructus Forsythiae, Flos Lonicerae, Herba Polygoni cymosi, Herba Artemisiae annuae, Radix Angelicae Sinensis according to prescription ratio mix homogeneously, jointly it is ground into coarser powder, crosses 90 mesh sieves, and by the thick medicamental pulverata after sieving and vitamin B6, metronidazole be mixed and made into tablet, every 30 is one bottle, is packaged as finished product.
In above-mentioned prescription, every part is 5g.
Embodiment 3
A kind of medicine treating eczema, in parts by weight, its proportioning is each component of this medicine: Fructus Forsythiae 20 parts, Flos Lonicerae 5 parts, Herba Polygoni cymosi 17 parts, Herba Artemisiae annuae 1 part, vitamin B67 parts, Radix Angelicae Sinensis 4 parts, metronidazole 2 parts.
By Fructus Forsythiae, Flos Lonicerae, Herba Polygoni cymosi, Herba Artemisiae annuae, Radix Angelicae Sinensis according to prescription ratio mix homogeneously, jointly it is ground into coarser powder, crosses 80 mesh sieves, and by the thick medicamental pulverata after sieving and vitamin B6, metronidazole be mixed and made into tablet, every 30 is one bottle, is packaged as finished product.
In above-mentioned prescription, every part is 5g.
Embodiment 4
A kind of medicine treating eczema, in parts by weight, its proportioning is each component of this medicine: Fructus Forsythiae 15 parts, Flos Lonicerae 7 parts, Herba Polygoni cymosi 20 parts, Herba Artemisiae annuae 2 parts, vitamin B68 parts, Radix Angelicae Sinensis 3 parts, metronidazole 2 parts.
By Fructus Forsythiae, Flos Lonicerae, Herba Polygoni cymosi, Herba Artemisiae annuae, Radix Angelicae Sinensis according to prescription ratio mix homogeneously, jointly it is ground into coarser powder, crosses 70 mesh sieves, and by the thick medicamental pulverata after sieving and vitamin B6, metronidazole be mixed and made into tablet, every 30 is one bottle, is packaged as finished product.
In above-mentioned prescription, every part is 3g.
Embodiment 5
A kind of medicine treating eczema, in parts by weight, its proportioning is each component of this medicine: Fructus Forsythiae 12 parts, Flos Lonicerae 8 parts, Herba Polygoni cymosi 10 parts, Herba Artemisiae annuae 3 parts, vitamin B65 parts, Radix Angelicae Sinensis 4 parts, metronidazole 1 part.
By Fructus Forsythiae, Flos Lonicerae, Herba Polygoni cymosi, Herba Artemisiae annuae, Radix Angelicae Sinensis according to prescription ratio mix homogeneously, jointly it is ground into coarser powder, crosses 50 mesh sieves, and by the thick medicamental pulverata after sieving and vitamin B6, metronidazole be mixed and made into tablet, every 30 is one bottle, is packaged as finished product.
In above-mentioned prescription, every part is 10g.
Embodiment 6
A kind of medicine treating eczema, in parts by weight, its proportioning is each component of this medicine: Fructus Forsythiae 17 parts, Flos Lonicerae 9 parts, Herba Polygoni cymosi 18 parts, Herba Artemisiae annuae 1 part, vitamin B68 parts, Radix Angelicae Sinensis 5 parts, metronidazole 1 part.
By Fructus Forsythiae, Flos Lonicerae, Herba Polygoni cymosi, Herba Artemisiae annuae, Radix Angelicae Sinensis according to prescription ratio mix homogeneously, jointly it is ground into coarser powder, crosses 100 mesh sieves, and by the thick medicamental pulverata after sieving and vitamin B6, metronidazole be mixed and made into tablet, every 30 is one bottle, is packaged as finished product.
In above-mentioned prescription, every part is 5g.
Experimental example 1
Guo patient, man, 28 years old, their early stage Face and cheek played red millet appearance erythra, diagnoses as eczema, provides through inventor, take the medicine of the treatment eczema that proportioning and method described in the embodiment of the present invention 1 prepare, once a piece of, three times on the one, a course for the treatment of on the 5th. 10 days, interval, then second course for the treatment of. Continuous two courses for the treatment of. Patient reacts good, has no side effect, recovery from illness.
Experimental example 2
Patient's Qi, female, 31 years old, their early stage Face and cheek played red millet appearance erythra, itching in local, diagnoses as eczema, provides through inventor, takes the medicine of the treatment eczema that proportioning and method described in the embodiment of the present invention 2 prepare, once a piece of, a twice-daily, a course for the treatment of on the 8th. 10 days, interval, then second course for the treatment of. Continuous two courses for the treatment of. Patient fully recovers, and has no side effect.
Experimental example 3
Patient cattle, female, 49 years old, pudendal pruritus more than 20 sky, very itching twinge in local, western medicine for several times, touching is not healed, and provides through inventor, take the medicine of the treatment eczema that proportioning and method described in the embodiment of the present invention 3 prepare, once a piece of, once a day, a course for the treatment of on the 10th. 10 days, interval, then second course for the treatment of. Continuous two courses for the treatment of. Patients symptomatic disappears, and has no side effect.
During with drug test provided by the present invention, treatment group eczema patients 157 example, provided by the present invention medicine 3 slice is administered orally every day, altogether treatment 12 months; Matched group patient 88 example, takes placebo (without the starch sheet that any pharmaceutical component, profile and medicine provided by the present invention are alike). Result shows, the symptom for the treatment of group patient is obviously improved, effective percentage respectively 62.0%~73.0%; The repeated infection of patient significantly reduces; Difference significance (P < 0.05) compared with matched group. The above results shows that medicine provided by the present invention has significant curative effect.

Claims (4)

1. the medicine treating eczema, it is characterised in that: in parts by weight, its proportioning is each component of this medicine: Fructus Forsythiae 10-20 part, Flos Lonicerae 5-10 part, Herba Polygoni cymosi 10-20 part, Herba Artemisiae annuae 1-3 part, vitamin B65-8 part, Radix Angelicae Sinensis 3-5 part, metronidazole 1-2 part.
2. the medicine for the treatment of eczema according to claim 1, it is characterized in that: in parts by weight, its proportioning is each component of this medicine: Fructus Forsythiae 15 parts, Flos Lonicerae 10 parts, Herba Polygoni cymosi 15 parts, Herba Artemisiae annuae 3 parts, vitamin B6 8 parts, Radix Angelicae Sinensis 4 parts, metronidazole 1 part.
3. the method for the processing medicine treating eczema as claimed in claim 1, it is characterized in that: by Fructus Forsythiae, Flos Lonicerae, Herba Polygoni cymosi, Herba Artemisiae annuae, Radix Angelicae Sinensis according to prescription ratio mix homogeneously, jointly it is ground into coarser powder, sieves, and by the thick medicamental pulverata after sieving and vitamin B6, metronidazole be mixed and made into tablet, every 30 is one bottle, is packaged as finished product.
4. the method for the medicine of processing treatment eczema according to claim 3, it is characterised in that: the coarser powder after pulverizing crosses 50-100 mesh sieve.
CN201610140938.2A 2016-03-11 2016-03-11 Drug for treating eczema Pending CN105663270A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610140938.2A CN105663270A (en) 2016-03-11 2016-03-11 Drug for treating eczema

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610140938.2A CN105663270A (en) 2016-03-11 2016-03-11 Drug for treating eczema

Publications (1)

Publication Number Publication Date
CN105663270A true CN105663270A (en) 2016-06-15

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201610140938.2A Pending CN105663270A (en) 2016-03-11 2016-03-11 Drug for treating eczema

Country Status (1)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112915147A (en) * 2019-11-21 2021-06-08 宋储羽 Ointment for treating skin diseases and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112915147A (en) * 2019-11-21 2021-06-08 宋储羽 Ointment for treating skin diseases and preparation method thereof

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Application publication date: 20160615