CN105641530A - 一种治疗色素斑的中药组合物 - Google Patents
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Abstract
本发明公开了一种治疗色素斑的中药组合物,其中药原料及重量份配比为:菟丝子10-30份,茯苓10-20份,柴胡5-15份,当归10-20份,黄芪10-20份,玫瑰花10-20份,荆芥10-20份,山萸肉10-20份,紫草10-20份,女贞子10-20份,牡丹皮5-15份,山药10-30份,鸡血藤10-20份,肉桂5-15份,白茅根10-20份,白芷10-20份,桃仁10-20份,仙鹤草10-20份,阿胶5-15份,益母草5-15份,大青叶10-20份,甘草5-15份。本发明中药组合物具有疏肝解郁、补脾益气、凉血祛湿、清热泻火的功效,其治疗色素斑疗效显著,作用可靠。
Description
技术领域
本发明涉及一种传统草药的未确定结构的医用配制品,尤其是一种治疗色素斑的中药组合物。
背景技术
色素斑是发生于皮肤表面的一种色素沉着性皮肤病,系指皮肤黑色素颗粒分布不均匀,导致皮肤局部出现比正常肤色深的斑点、斑片。其中,日晒过度、内分泌失调、慢性肝肠胃疾病、化妆品使用不当等,都可能是引起色素斑的诱因。色素斑多发于青春期后的女性,病情可有季节性,常夏重冬轻。患者虽无明显不适,但有碍美观,造成心理压力,影响工作和生活。目前,临床上常采用冷冻疗法、电灼法、化学腐脱法治疗色素斑。上述治疗方法均是以破坏皮肤表层为特点的方法,虽有一定效果,但费用高,创面愈合慢且易复发。
中医认为,色素斑是因肝气郁结、肝经火旺、脾失健运和湿热内生所致,以皮肤黑色素分别不均匀为特征的慢性皮肤病。
根据中医理论,针对色素斑的发病机理,以疏肝解郁、补脾益气、凉血祛湿为治则,进行辩证配伍组方,以达到标本兼治的目的。
发明内容
为了克服现有技术中手术疗法治疗色素斑存在费用高、伤害大、易复发的不足,本发明提供一种配制方便、药源广、成本低、疗效显著、作用可靠、无副作用的治疗色素斑的中药组合物。
本发明解决其技术问题所采用的技术方案是:一种治疗色素斑的中药组合物,其特征在于:其中药原料及重量份配比为:菟丝子10-30份,茯苓10-20份,柴胡5-15份,当归10-20份,黄芪10-20份,玫瑰花10-20份,荆芥10-20份,山萸肉10-20份,紫草10-20份,女贞子10-20份,牡丹皮5-15份,山药10-30份,鸡血藤10-20份,肉桂5-15份,白茅根10-20份,白芷10-20份,桃仁10-20份,仙鹤草10-20份,阿胶5-15份,益母草5-15份,大青叶10-20份,甘草5-15份。
本发明的优选技术方案是:一种治疗色素斑的中药组合物,其特征在于:其中药原料及重量份配比为:菟丝子20份,茯苓15份,柴胡10份,当归15份,黄芪15份,玫瑰花15份,荆芥10份,山萸肉15份,紫草15份,女贞子15份,牡丹皮10份,山药20份,鸡血藤15份,肉桂10份,白茅根15份,白芷15份,桃仁15份,仙鹤草15份,阿胶10份,益母草10份,大青叶15份,甘草10份。
本发明中药组合物是在传统中医理论和临床经验指导下,精选药物组方。本发明中药组合物中:菟丝子具有补肾益精、养肝健脾的功效;茯苓具有清热解毒、祛湿利水、健脾胃、利关节的功效;柴胡具有疏散退热、升阳舒肝的功效;当归具有补血活血、调经止痛、润肠通便的功效;黄芪具有益气固表、补肺健脾、敛汗固脱、驱风运毒的功效;玫瑰花具有行气解郁、活血调经的功效;荆芥具有解表散风、透疹、消疮、止血的功效;山萸肉具有补益肝肾、涩精止汗的功效;紫草具有清热凉血、活血化瘀、解毒透疹的功效;女贞子具有滋阴清热、补肝明目的功效;牡丹皮具有清热凉血、活血散瘀的功效;山药具有健脾补肺、益胃补肾、固肾益精、聪耳明目、助五脏、强筋骨、长志安神、延年益寿的功效;鸡血藤具有补血活血、舒经通络的功效;肉桂具有补火助阳、散寒止痛、活血通经的功效;白茅根具有凉血止血、清热解毒的功效;白芷具有解表散寒、祛风通窍、活血止痛、燥湿止带、消肿排脓的功效;桃仁具有活血祛瘀、润肠通便的功效;仙鹤草具有收敛止血、健胃、截疟、解毒疗疮的功效;阿胶具有补血、止血、滋阴润燥的功效;益母草具有活血调经、祛瘀利水、清热解毒的功效;大青叶具有清热解毒、凉血止血的功效;甘草具有补脾益气、清热解毒、祛痰止咳、调和诸药的功效。本发明组合物中的药物组分经辩证配伍,在作用上相辅相成,具有协同作用,共奏疏肝解郁、补脾益气、凉血祛湿、清热泻火之功效,对色素斑达到标本兼治的目的。
本发明组合物的组分均采用天然的中药原料,其配制简便、药源广、成本低。其遵循中医的处方用药原则,各种组分药物采用水煎服用。经临床应用验证,其疗效显著,作用可靠,药性平和,未出现毒副作用,总有效率91%,治愈率达76%。
具体实施方式
下面结合实施例对本发明做进一步说明。
实施例1
一种治疗色素斑的中药组合物,其中药原料及重量配比为:菟丝子20g,茯苓15g,柴胡10g,当归15g,黄芪15g,玫瑰花15g,荆芥10g,山萸肉15g,紫草15g,女贞子15g,牡丹皮10g,山药20g,鸡血藤15g,肉桂10g,白茅根15g,白芷15g,桃仁15g,仙鹤草15g,阿胶10g,益母草10g,大青叶15g,甘草10g。
实施例2
一种治疗色素斑的中药组合物,其中药原料及重量配比为:菟丝子30g,茯苓10g,柴胡15g,当归10g,黄芪20g,玫瑰花10g,荆芥20g,山萸肉10g,紫草20g,女贞子10g,牡丹皮15g,山药10g,鸡血藤20g,肉桂5g,白茅根20g,白芷10g,桃仁20g,仙鹤草10g,阿胶15g,益母草5g,大青叶20g,甘草5g。
实施例3
一种治疗色素斑的中药组合物,其中药原料及重量配比为:菟丝子10g,茯苓20g,柴胡5g,当归20g,黄芪10g,玫瑰花20g,荆芥10g,山萸肉20g,紫草10g,女贞子20g,牡丹皮5g,山药30g,鸡血藤10g,肉桂15g,白茅根10g,白芷20g,桃仁10g,仙鹤草20g,阿胶5g,益母草15g,大青叶10g,甘草15g。
实施例4
一种治疗色素斑的中药组合物,其中药原料及重量配比为:菟丝子17g,茯苓12g,柴胡8g,当归12g,黄芪12g,玫瑰花12g,荆芥8g,山萸肉12g,紫草12g,女贞子12g,牡丹皮8g,山药17g,鸡血藤12g,肉桂8g,白茅根12g,白芷12g,桃仁12g,仙鹤草12g,阿胶8g,益母草8g,大青叶12g,甘草8g。
实施例5
一种治疗色素斑的中药组合物,其中药原料及重量配比为:菟丝子23g,茯苓17g,柴胡13g,当归17g,黄芪17g,玫瑰花17g,荆芥13g,山萸肉17g,紫草17g,女贞子17g,牡丹皮13g,山药23g,鸡血藤17g,肉桂13g,白茅根17g,白芷17g,桃仁17g,仙鹤草17g,阿胶13g,益母草13g,大青叶17g,甘草13g。
本发明实施例中的中药组合物按常规的水煎法制取药剂。具体方法如下:将组方的中药原料放入容器中,加冷水漫过药面,浸泡15~20分钟,再加水没过药面约8厘米,进行第一次煎煮,未沸前采用武火煎煮,沸后用文火煎煮20~30分钟;第二次煎煮,加水没过药面约6厘米,水沸后煎煮15~20分钟。两次煎煮去渣取汁,合并。
本发明以实施例1所给出的一种治疗色素斑的中药组合物,做临床疗效总结如下:
一、一般性资料:本发明中药组合物应用于临床观察病例100例,其中男20例,女80例,年龄25~60岁。
二、诊断标准:
1、面部呈红褐色或深红褐色的斑片,通常对称性分布,无炎症表现及鳞屑;
2、无明显自觉症状;
3、女性多发,主要发生在青春期后;
4、病情可有季节性,常夏重冬轻;
5、排除其他疾病引起的色素沉着。
三、用法用量:临床应用时,一天一剂,水煎两遍取汁约300ml,分早、晚两次饭前半小时温热服用,五天一疗程。
四、疗效标准:
1、治愈:肉眼视色素斑面积消退大于90%,颜色基本消失;
2、好转:肉眼视色素斑面积消退大于30%,颜色变淡;
3、未愈:肉眼视色素斑面积消退小于30%。
五、治疗效果:该临床观察病例中,服药4-10个疗程,治愈76例,好转15例,未愈9例。治疗期间未发生毒副作用。
六、典型病例:
病例1:孙某,女,32岁。自述面颈部、胸背部、腋下、乳房下以及双上肢长大片褐色斑;冬重夏轻,反复加重,并出现片状脱屑。服用本发明的中药组合物制备的药剂2个疗程后,自觉斑点减少,颜色变淡;继续服用4个疗程,斑面积消退,颜色正常,治愈。
病例2:杨某,男,47岁。自述初起时手背、面部等处常出现一块块褐色斑块,形状大小不一。随着时间的增长,斑点颜色越来越深,更为明显。服用本发明的中药组合物制备的药剂2个疗程,褐色斑块显著颜色减轻;续服5个疗程后,斑块消失,各部位颜色正常,治愈。
Claims (2)
1.一种治疗色素斑的中药组合物,其特征在于:其中药原料及重量份配比为:菟丝子10-30份,茯苓10-20份,柴胡5-15份,当归10-20份,黄芪10-20份,玫瑰花10-20份,荆芥10-20份,山萸肉10-20份,紫草10-20份,女贞子10-20份,牡丹皮5-15份,山药10-30份,鸡血藤10-20份,肉桂5-15份,白茅根10-20份,白芷10-20份,桃仁10-20份,仙鹤草10-20份,阿胶5-15份,益母草5-15份,大青叶10-20份,甘草5-15份。
2.根据权利要求1所述的一种治疗色素斑的中药组合物,其特征在于:其中药原料及重量份配比为:菟丝子20份,茯苓15份,柴胡10份,当归15份,黄芪15份,玫瑰花15份,荆芥10份,山萸肉15份,紫草15份,女贞子15份,牡丹皮10份,山药20份,鸡血藤15份,肉桂10份,白茅根15份,白芷15份,桃仁15份,仙鹤草15份,阿胶10份,益母草10份,大青叶15份,甘草10份。
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