CN105641092A - Ointment medicine treating rheumatic arthritis and preparing method thereof - Google Patents

Ointment medicine treating rheumatic arthritis and preparing method thereof Download PDF

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Publication number
CN105641092A
CN105641092A CN201610162590.7A CN201610162590A CN105641092A CN 105641092 A CN105641092 A CN 105641092A CN 201610162590 A CN201610162590 A CN 201610162590A CN 105641092 A CN105641092 A CN 105641092A
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medicine
rheumatic arthritis
fructus
radix
ointment
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罗兴兰
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Sichuan Shuangxin Biological Technology Co Ltd
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Sichuan Shuangxin Biological Technology Co Ltd
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    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708Rheum (rhubarb)
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Abstract

An ointment medicine treating rheumatic arthritis and a preparing method thereof belong to the technical field of traditional Chinese medicine. The invention aims to provide an ointment medicine treating rheumatic arthritis according to an understanding mechanism of traditional Chinese medicine on the rheumatic arthritis. The medicine is prepared from the following components in parts by mass: 0.4-0.7g of whin, 5-20g of sub rheum officinale, 10-16g of radix clematidis, 1.5-3g of aconitum pendulum busch, 5-16 parts of enucleated fructus chebulae, 15-26g of Tripterygium wilfordii, 3-10g of fructus teminaliae billaricae, 15-32g of emblic leafflower fruit, 0.5-3g of benzoin, 10-32g of Tinospora sinensis Merr, 0.05-0.13g of muskone, 1.5-3g of radix aconiti preparata and a proper part of chlorhexidine acetate. The medicine is a good traditional Chinese medicine formula.

Description

A kind of ointment medicine treating rheumatic arthritis and preparation method
Technical field
The present invention relates to technical field of Chinese medicine, be specifically related to a kind of ointment medicine treating rheumatic arthritis, the ointment medicine used especially for rheumatoid arthritis patients and the field of preparation method.
Background technology
Rheumatic arthritis is a kind of common acute or chronic ICT. Rheumatic arthritis broadly should include rheumatoid arthritis. Can recurrent exerbation, and involve heart. Clinical with joint and muscle migrans miserable, heavily work, pain is for feature. Belong to allergic disease. It is one of the main manifestations of rheumatic fever, how with febris acuta and arthralgia onset.
So, just how to find a kind of medicine that can effectively treat rheumatic arthritis, be our current problem in urgent need to solve.
Summary of the invention
Development along with China's Chinese medicine, in treatment rheumatic arthritis, the advantage that people appreciate the above-mentioned rheumatic arthritis of Chinese traditional treatment gradually, and the advantage such as toxic and side effects is little over the course for the treatment of, expense is low, present situation for the above-mentioned rheumatic arthritis of existing western medical treatment, it is an object of the invention to be in that to provide a kind of ointment medicine treating rheumatic arthritis, to solve rheumatoid arthritis patients's restorative problem early. This medicine is with common Chinese medicine for raw material, has instant effect, the feature such as evident in efficacy, and can effectively treat above-mentioned rheumatic arthritis.
For reaching the purpose of foregoing invention, the technical solution adopted in the present invention is: provide a kind of ointment medicine treating rheumatic arthritis and preparation method, it is characterised in that each component of described medicine and mass parts ratio thereof are as follows:
Herba Oxytropis Kansuensis 0.4��0.7g, sub-rhubarb extract 5��20g, Radix Clematidis 10��16g, Radix aconiti szechenyiani 1.5��3g, Fructus Chebulae's (enucleation) 5��16g, Radix Tripterygii Wilfordii 15��26g, Fructus Terminaliae Billericae 3��10g, Fructus Phyllanthi 15��32g, Benzoinum 0.5��3g, Herba Lycopodii 10��32g, artificial Moschus 0.05��0.13g, Radix Aconiti Preparata 1.5��3g, chlorhexidine acetate is appropriate.
A kind of ointment medicine treating rheumatic arthritis and preparation method, it is characterised in that each component of described medicine and mass parts ratio thereof are as follows:
Herba Oxytropis Kansuensis 0.4��0.6g, sub-rhubarb extract 10��17g, Radix Clematidis 11��14g, Radix aconiti szechenyiani 1.8��2.5g, Fructus Chebulae's (enucleation) 8��14g, Radix Tripterygii Wilfordii 18��23g, Fructus Terminaliae Billericae 6��9g, Fructus Phyllanthi 18��27g, Benzoinum 0.8��2.5g, Herba Lycopodii 15��27g, artificial Moschus 0.06��0.11g, Radix Aconiti Preparata 1.8��2.7g, chlorhexidine acetate is appropriate.
A kind of ointment medicine treating rheumatic arthritis and preparation method, it is characterised in that each component and the mass parts ratio thereof of the medicine of described " preferred plan " are as follows:
Herba Oxytropis Kansuensis 0.5g, sub-rhubarb extract 15g, Radix Clematidis 13g, Radix aconiti szechenyiani 2.3g, Fructus Chebulae's (enucleation) 13g, Radix Tripterygii Wilfordii 20g, Fructus Terminaliae Billericae 8g, Fructus Phyllanthi 25g, Benzoinum 2.3g, Herba Lycopodii 25g, artificial Moschus 0.10g, Radix Aconiti Preparata 2.5g, chlorhexidine acetate is appropriate.
A kind of ointment medicine treating rheumatic arthritis and preparation method, it is characterised in that described method comprises the steps to be prepared from:
A, above-mentioned raw materials Chinese medicine is picked decontamination and dust after, be ground into superfine end (adopting ultra tiny machine to grind) according to mass parts ratio stand-by;
B, the method traditionally preparing Chinese medicine ointment, after being sieved by ground superfine myrrh thing, put in special-purpose stirring machine container and be stirred, to be mixed uniformly rear standby;
C, the superfine myrrh thing stirred is put into mixer container, add appropriate chlorhexidine acetate and mix all, obtain ointment final drug, seal.
A kind of using method of the ointment medicine of above-mentioned treatment rheumatic arthritis, it is characterized in that, described using method is: ointment final drug is applied to the site of disease cleaned up, (please don't be administered orally for 2 times on the one, damaged skin, anemia of pregnant woman's disabling), after treating 1��3 week, symptom alleviates gradually or fully recovers.
Each raw material Chinese medicine in prescription of the present invention is all documented in detail in Chinese Pharmacopoeia, China's dictionary and China's book on Chinese herbal medicine. The present invention selects most common of which Chinese medicine to be raw material, gives full play to the pharmacological effect of each component:
Herba Oxytropis Kansuensis, nature and flavor: bitter, cold, poisonous, there is heat-clearing and toxic substances removing, granulation promoting heals skin ulcer, hesitant pulse hemostasis, relieving constipation effect, be used for treating epidemic disease, toxonosis, grasserie, constipation, anthrax, external application is controlled furuncle and the disease such as is swollen and ache;
Sub-rhubarb extract, nature and flavor: bitter, cold, have that removing the relative excess heat, removing mass be stagnant, effect of clots absorbing blood, for treating excess-heat constipation, food stagnation stagnation, stomachache, acute appendicitis, acute infectious hepatitis, blood stasis amenorrhea, toothache, epistaxis, acute conjunctivitis, the diseases such as burn and scald, suppurative dermatosis, carbuncle skin infection are controlled in external;
Radix Clematidis, nature and flavor: acrid in the mouth, hardship salty, micro-, warm in nature, mild toxicity, has effect of expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, is used for treating rheumatic arthralgia, numb limbs and tense tendons, muscle arteries and veins contracture, joint stuffiness, beriberi swells and ache, malaria, bone choke with sobs larynx and controls phlegm retention the disease such as gathering;
Radix aconiti szechenyiani, nature and flavor: bitter, pungent, warm, poisonous, there is effect of blood circulation promoting and blood stasis dispelling, expelling wind and removing dampness, reducing swelling and alleviating pain, be used for treating the disease such as traumatic injury, fracture pain caused by ecchymoma, lumbago due to pathogenic wind-dampness, carbuncle malignant boil, innominate toxic swelling, scrofula routed person, venom, chilblain;
Fructus Chebulae's (enucleation), nature and flavor: bitter in the mouth, acid, puckery, property are put down, have astringe the lung, effect of astringing intestine to stop diarrhea, the therapeutic method to keep the adverse QI flowing downwards, sore-throat relieving, be used for treating the diseases such as chronic diarrhea, chronic dysentery, proctoptosis, phlegmatic cough of breathing with cough, chronic cough aphonia;
Radix Tripterygii Wilfordii, nature and flavor: bitter, pungent, big poison, there is effect of expelling wind and removing dampness, promoting blood circulation to remove obstruction in the collateral, reducing swelling and alleviating pain, parasite killing removing toxic substances, be used for treating rheumatoid arthritis, rheumatic arthritis, glomerulonephritis, nephrotic syndrome, lupus erythematosus, mouth xerophthalmia scheorma syndrome, Behcet disease, eczema, psoriasis, leprosy, scabies, stubborn dermatitis;
Fructus Terminaliae Billericae, nature and flavor: sweet, puckery, flat, there is heat-clearing and toxic substances removing, convergence is nourished blood, effect of coordinating the actions of various ingredients in a prescription, be used for treating various heat symptom-complex, dysentery, grasserie, liver-gallbladder disease, the after being ill disease such as weak;
Fructus Phyllanthi, nature and flavor: bitter in the mouth, sweet, sour, cool in nature, there is effect of relieving sore-throat by clearing away heat, moistening the lung and resolving phlegm, promoting the production of body fluid to quench thirst, be used for treating the diseases such as cold, fever, cough, pharyngalgia, diphtheria, thirsty, the hypertension of dysphoria with smothery sensation;
Benzoinum, nature and flavor: pungent, bitter, property is put down, there is refreshment of having one's ideas straightened out, eliminating phlegm wards off dirty, promoting flow of QI and blood, effect of pain relieving, for diseases such as wind-phlegm Jue, infantile convulsion stupor, puerperal blood faints, trusted subordinate's pain, migratory arthralgia arthrodynia of the extremities in treatment;
Herba Lycopodii, nature and flavor: mildly bitter flavor, cool in nature, there is effect of wind-expelling pain-stopping, relaxing muscles and tendons and activating QI and blood in the collateral, be used for treating the diseases such as rheumatic arthralgia, lumbar muscle strain, traumatic injury;
Artificial Moschus, nature and flavor: have special fragrance, have bitterness, there is the effects such as causing resuscitation with aromatic drugs, promoting blood circulation to restore menstrual flow, reducing swelling and alleviating pain, can coronary artery dilator, Antianginal effect is similar to nitroglycerin;
Radix Aconiti Preparata, nature and flavor: pungent, bitter, hot, poisonous, there is effect of expelling wind and removing dampness, antalgic, be used for treating anemofrigid-damp arthralgia, the disease such as mastalgia, chest pain with distension sensation, arthralgia, trusted subordinate's cold type of pain, colic of cold type are had a pain, narcotic analgesic.
Medicine of the present invention is based on the differential diagnosis of diseases of Chinese traditional treatment rheumatic arthritis and the dialectical principle combined, think from pharmacological action and mechanism of action: with regard to rheumatic arthritis one disease, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, and above-mentioned disease is had good therapeutic effect.
Detailed description of the invention
The present invention is aiming at the treatment of above-mentioned rheumatic arthritis and a kind of Chinese medicine formula of proposing, adopts medicine effect prepared by this formula good, and instant effect, is the Chinese prescription of a treating both the principal and secondary aspects of a disease, is particularly suitable for Clinical practice. It is described in further detail below in conjunction with the specific embodiment of the present invention:
Embodiment 1:
A kind of ointment medicine treating rheumatic arthritis, it is characterised in that each component of described medicine and mass parts ratio are as follows:
Herba Oxytropis Kansuensis 0.5g, sub-rhubarb extract 15g, Radix Clematidis 13g, Radix aconiti szechenyiani 2.3g, Fructus Chebulae's (enucleation) 13g, Radix Tripterygii Wilfordii 20g, Fructus Terminaliae Billericae 8g, Fructus Phyllanthi 25g, Benzoinum 2.3g, Herba Lycopodii 25g, artificial Moschus 0.10g, Radix Aconiti Preparata 2.5g, chlorhexidine acetate is appropriate.
Embodiment 2:
A kind of ointment medicine treating rheumatic arthritis, it is characterised in that each component of described medicine and mass parts ratio are as follows:
Herba Oxytropis Kansuensis 0.6g, sub-rhubarb extract 17g, Radix Clematidis 14g, Radix aconiti szechenyiani 2.5g, Fructus Chebulae's (enucleation) 14g, Radix Tripterygii Wilfordii 23g, Fructus Terminaliae Billericae 9g, Fructus Phyllanthi 27g, Benzoinum 2.5g, Herba Lycopodii 27g, artificial Moschus 0.11g, Radix Aconiti Preparata 2.7g, chlorhexidine acetate is appropriate.
Embodiment 3:
A kind of ointment medicine treating rheumatic arthritis, it is characterised in that each component of described medicine and mass parts ratio are as follows:
Herba Oxytropis Kansuensis 0.7g, sub-rhubarb extract 20g, Radix Clematidis 16g, Radix aconiti szechenyiani 3g, Fructus Chebulae's (enucleation) 16g, Radix Tripterygii Wilfordii 26g, Fructus Terminaliae Billericae 10g, Fructus Phyllanthi 32g, Benzoinum 3g, Herba Lycopodii 32g, artificial Moschus 0.13g, Radix Aconiti Preparata 3g, chlorhexidine acetate is appropriate.
Model case:
Through clinical conditions rheumatoid arthritis patients totally 160 example, the age is 100 examples of more than 48 years old, and only 60 examples are less than 48 years old. 135 examples of recovery from illness in 160 example patients, 25 effective examples, total effective rate reaches 100%. After treatment, symptom alleviates gradually or fully recovers.

Claims (3)

1. the ointment medicine treating rheumatic arthritis, it is characterised in that each component of described medicine and mass parts ratio thereof are as follows:
Herba Oxytropis Kansuensis 0.4��0.7g, sub-rhubarb extract 5��20g, Radix Clematidis 10��16g, Radix aconiti szechenyiani 1.5��3g, Fructus Chebulae's (enucleation) 5��16g, Radix Tripterygii Wilfordii 15��26g, Fructus Terminaliae Billericae 3��10g, Fructus Phyllanthi 15��32g, Benzoinum 0.5��3g, Herba Lycopodii 10��32g, artificial Moschus 0.05��0.13g, Radix Aconiti Preparata 1.5��3g, chlorhexidine acetate is appropriate.
2. the ointment medicine for the treatment of rheumatic arthritis according to claim 1, it is characterised in that each component of described medicine and mass parts ratio thereof are as follows:
Herba Oxytropis Kansuensis 0.4��0.6g, sub-rhubarb extract 10��17g, Radix Clematidis 11��14g, Radix aconiti szechenyiani 1.8��2.5g, Fructus Chebulae's (enucleation) 8��14g, Radix Tripterygii Wilfordii 18��23g, Fructus Terminaliae Billericae 6��9g, Fructus Phyllanthi 18��27g, Benzoinum 0.8��2.5g, Herba Lycopodii 15��27g, artificial Moschus 0.06��0.11g, Radix Aconiti Preparata 1.8��2.7g, chlorhexidine acetate is appropriate.
3. the ointment medicine of the treatment rheumatic arthritis according to claim 1 to 2, it is characterised in that each component of described medicine and mass parts ratio thereof are as follows:
Herba Oxytropis Kansuensis 0.5g, sub-rhubarb extract 15g, Radix Clematidis 13g, Radix aconiti szechenyiani 2.3g, Fructus Chebulae's (enucleation) 13g, Radix Tripterygii Wilfordii 20g, Fructus Terminaliae Billericae 8g, Fructus Phyllanthi 25g, Benzoinum 2.3g, Herba Lycopodii 25g, artificial Moschus 0.10g, Radix Aconiti Preparata 2.5g, chlorhexidine acetate is appropriate.
CN201610162590.7A 2016-03-22 2016-03-22 Ointment medicine treating rheumatic arthritis and preparing method thereof Withdrawn CN105641092A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106109631A (en) * 2016-09-07 2016-11-16 四川金堂海纳生物医药技术研究所 A kind of pill medicine treating rheumatic arthritis and preparation method thereof
CN107970379A (en) * 2016-10-21 2018-05-01 钟伟权 The ointment medicine and preparation method of a kind of wind-damp dispelling
CN108553522A (en) * 2018-04-02 2018-09-21 青海省通天河藏药制药有限责任公司 A kind of anti-inflammatory analgetic Tibetan medicine promoting blood circulation and removing blood stasis and preparation method thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106109631A (en) * 2016-09-07 2016-11-16 四川金堂海纳生物医药技术研究所 A kind of pill medicine treating rheumatic arthritis and preparation method thereof
CN107970379A (en) * 2016-10-21 2018-05-01 钟伟权 The ointment medicine and preparation method of a kind of wind-damp dispelling
CN108553522A (en) * 2018-04-02 2018-09-21 青海省通天河藏药制药有限责任公司 A kind of anti-inflammatory analgetic Tibetan medicine promoting blood circulation and removing blood stasis and preparation method thereof

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