CN105640486A - Anterior chamber of eye volume determining method and apparatus - Google Patents

Abstract

The invention discloses an anterior chamber of eye volume determining method and apparatus. The method comprises steps of acquiring an original scanning image of a prosthomere OCT, selecting a first number of prosthomere OCT from the original scanning image, displaying the prosthomere OCT image and drawing an anterior chamber of the eye image, dividing the anterior chamber of the eye via a preset second number of longitudinal lines, calculating the length of an intersected part between each longitudinal line and the anterior chamber of the eye in each divided part, and calculating the anterior chamber of eye volume of the anterior chamber image according to the length of the intersected part between each longitudinal line and the anterior chamber of the eye and division line numbers. The anterior chamber of the eye is equally divided by the prosthomere OCT image scanning position; and the preset first number is an even number. Deficiencies of anterior chamber of eye volume measurement in the prior art can be overcome by the use of the anterior chamber of eye volume determining method and apparatus, and the anterior chamber of eye volume can be accurately acquired; cost can be lowered; and economic benefits can be increased.

Description

A kind of method and device determining anterior chamber of the eye volume

Technical field

The present invention relates to medical detection technology, particularly relate to a kind of method and the device of determining anterior chamber of the eye volume.

Background technology

Glaucoma is one of the whole world main illness in eye causing visual loss, if do not taked in time and effectively treat, the visual field or eyesight can all be lost, thus finally cause blind. And this kind of glaucoma cause blind, current medical treatments also cannot reverse, and therefore glaucoma has been primary or secondary irreversible causes of blindness in western countries, also comes front three in China. By early stage discovery and intervention, it is possible to make the function of major part patient be maintained. Therefore, the early discovery of glaucoma is particularly important.

Due to difference in crowds, in west, open angle glaucoma accounts for the overwhelming majority, and accounts for quite a few at China's angle closure glaucoma. For angle closure glaucoma, the measurement of anterior chamber angle and anterior chamber's volume is a kind of important method of early screening. Clinical in the examination of anterior chamber angle at present, but there is the shortcomings such as subjective, poor repeatability, not easily unified contrast. The measurement of anterior chamber's volume is not promoted due to the restriction of equipment and method yet.

Anterior chamber's volumetric measurement of current OCT mainly contains 2 kinds: utilize individual OCT of visante horizontal image measurement anterior chamber's volume and tomeyOCT up-to-date at present to utilize multiple image measurements anterior chamber's volume. Due to the spheroid that eyeball is irregular, the diameter in each orientation is also different, so individual level view picture can not measure the size of anterior chamber's volume accurately. And TomeyOCT adopts 8 images to calculate anterior chamber's volume, although relatively accurately, but due to expensive, popularity rate is not high, and owing to scanning 8 orientation simultaneously, it is easy to cause wherein 1,2 orientation to cause measuring error owing to eyelid blocks.

Given this, it is provided that a kind of improve diagnosis and treatment efficiency while fully cost-effective can determine that the method for anterior chamber of the eye volume and device are necessary.

Summary of the invention

It is an object of the invention to provide a kind of method and the device of determining anterior chamber of the eye volume, to help the ophthalmic diseases such as early discovery and diagnosis glaucoma, it is possible to fully save cost while improving diagnosis and treatment efficiency.

For solving the problems of the technologies described above, the present invention provides a kind of method determining anterior chamber of the eye volume, comprising:

Obtain the original scan image of prosthomere OCT;

Choosing the prosthomere OCT image of default first quantity from described original scan image, described prosthomere OCT image scanning position etc. point anterior chamber, described default first quantity is even number;

Described prosthomere OCT image is shown, depicts anterior chamber's image;

By presetting the vertical line of the 2nd quantity, described anterior chamber's image is split, the length of each vertical line and anterior chamber's intersection in each several part of computation partition;

By described each vertical line and the length of anterior chamber's intersection and the quantity of described vertical line, calculate anterior chamber of the eye volume in described anterior chamber's image.

Can selection of land, the described prosthomere OCT image choosing default first quantity from described original scan image comprises:

Remove the image that scanning is imperfect, from the described original scan image that scanning is complete, choose the prosthomere OCT image of default first quantity.

Can selection of land, described by described each vertical line and the length of anterior chamber's intersection and the quantity of described vertical line, calculate anterior chamber of the eye volume in described anterior chamber's image and comprise:

By described each vertical line and the length of anterior chamber's intersection and the quantity of described vertical line, according to:

$\begin{array}{c}\underset{i=0}{\overset{99}{\Σ}}\left(i+0.5\right){\∫}_0^{\frac{\mathrm{\π}}{2}}\sqrt{c^2{\sin }^2\mathrm{\θ}+d^2{\cos }^2\mathrm{\θ}}\\ \×\[\left(1-\frac{2\mathrm{\θ}}{\mathrm{\π}}\right)\left(a_{101-i}+a_{100-i}+a_{101+i}+a_{102+i}\right)+\frac{2\mathrm{\θ}}{\mathrm{\π}}\left(b_{101-i}+b_{100-i}+b_{101+i}+b_{102+i}\right)\]\×\[\left(1-\frac{2\mathrm{\θ}}{\mathrm{\π}}\right)c+\frac{2\mathrm{\θ}}{\mathrm{\π}}d\]d\mathrm{\θ}\end{array}$

Calculate the anterior chamber of the eye volume in described anterior chamber's image; Parameter interpretation wherein is as follows: by two orthogonal planes, the eyeball quartern obtains two cross sections, by two cross sections along transverse axis direction 200 decile, by Along ent place from iris crystal front surface trace line to the distance of corneal endothelium trace line, the height being called trace line, the height of the trace line of one of them planar interception is designated asSpacing between Along ent is designated as c; The height of the trace line of another planar interception vertical with it is designated asSpacing between Along ent is designated as d.

Present invention also offers a kind of device determining anterior chamber of the eye volume, comprising:

Acquisition module, for obtaining the original scan image of prosthomere OCT;

Choose module, for choosing the prosthomere OCT image of default first quantity from described original scan image, described prosthomere OCT image scanning position etc. point anterior chamber, described default first quantity is even number;

Display module, for being shown by described prosthomere OCT image, depicts anterior chamber's image;

Calculate module, for described anterior chamber's image being split by presetting the vertical line of the 2nd quantity, the length of each vertical line and anterior chamber's intersection in each several part of computation partition;

Determination module, for by the length of described each vertical line and anterior chamber's intersection and the quantity of described vertical line, calculating anterior chamber of the eye volume in described anterior chamber's image.

Can selection of land, described in choose module specifically for:

Remove the image that scanning is imperfect, from the described original scan image that scanning is complete, choose the prosthomere OCT image of default first quantity.

Can selection of land, described determination module specifically for:

By described each vertical line and the length of anterior chamber's intersection and the quantity of described vertical line, according to

$\begin{array}{c}\underset{i=0}{\overset{99}{\Σ}}\left(i+0.5\right){\∫}_0^{\frac{\mathrm{\π}}{2}}\sqrt{c^2{\sin }^2\mathrm{\θ}+d^2{\cos }^2\mathrm{\θ}}\\ \×\[\left(1-\frac{2\mathrm{\θ}}{\mathrm{\π}}\right)\left(a_{101-i}+a_{100-i}+a_{101+i}+a_{102+i}\right)+\frac{2\mathrm{\θ}}{\mathrm{\π}}\left(b_{101-i}+b_{100-i}+b_{101+i}+b_{102+i}\right)\]\×\[\left(1-\frac{2\mathrm{\θ}}{\mathrm{\π}}\right)c+\frac{2\mathrm{\θ}}{\mathrm{\π}}d\]d\mathrm{\θ}\end{array}$

Calculate the anterior chamber of the eye volume in described anterior chamber's image, parameter interpretation wherein is as follows: by two orthogonal planes, the eyeball quartern obtains two cross sections, by two cross sections along transverse axis direction 200 decile, by Along ent place from iris crystal front surface trace line to the distance of corneal endothelium trace line, the height being called trace line, the height of the trace line of one of them planar interception is designated asSpacing between Along ent is designated as c;The height of the trace line of another planar interception vertical with it is designated asSpacing between Along ent is designated as d.

The method of determination anterior chamber of the eye volume provided by the present invention and device, by obtaining the original scan image of prosthomere OCT; The prosthomere OCT image of point anterior chambers such as default first quantity is chosen from original scan image; Prosthomere OCT image is shown, depicts anterior chamber's image; By presetting the vertical line of the 2nd quantity, anterior chamber's image is split, the length of each vertical line and anterior chamber's intersection in each several part of computation partition; By each vertical line and the length of anterior chamber's intersection and the quantity of vertical line, calculate anterior chamber of the eye volume in anterior chamber's image. The method of determination anterior chamber of the eye volume provided by the present invention and device, it is possible to overcome the deficiency of current anterior chamber's volumetric measurement, more accurately obtain anterior chamber's volume, can also save cost simultaneously, increases economic benefit.

Accompanying drawing explanation

Fig. 1 is the schema of a kind of embodiment of the method for determination anterior chamber of the eye volume provided by the present invention;

Fig. 2 is the schema of another kind of embodiment of the method for determination anterior chamber of the eye volume provided by the present invention;

Fig. 3 is the schematic diagram being undertaken OCT image splitting;

The structure block diagram of the device of the determination anterior chamber of the eye volume that Fig. 4 provides for the embodiment of the present invention.

Embodiment

In order to make those skilled in the art understand the present invention program better, below in conjunction with the drawings and specific embodiments, the present invention is described in further detail. Obviously, described embodiment is only the present invention's part embodiment, instead of whole embodiments. Based on the embodiment in the present invention, those of ordinary skill in the art, not making other embodiments all obtained under creative work prerequisite, belong to the scope of protection of the invention.

As shown in Figure 1, the method comprises the schema of a kind of embodiment of the method for determination anterior chamber of the eye volume provided by the present invention:

Step S101: the original scan image obtaining prosthomere OCT;

Step S102: the prosthomere OCT image choosing default first quantity from described original scan image, described prosthomere OCT image scanning position etc. point anterior chamber, described default first quantity is even number;

It is noted that the method for determination anterior chamber of the eye volume provided by the present invention can take the prosthomere OCT image of any even number, only it is required to be the surface sweeping line of decile anterior chamber. As surface sweeping line be 1 time, it is possible to be any angle; As sweep trace be 2 time, must be vertical between these two sweep traces, thus anterior chamber is divided into the quartern; As sweep trace be 3 time, between it be 60 degree, 6 grades divide anterior chamber; Analogize with this.

Step S103: described prosthomere OCT image is shown, depicts anterior chamber's image;

Step S104: by presetting the vertical line of the 2nd quantity, described anterior chamber's image is split, the length of each vertical line and anterior chamber's intersection in each several part of computation partition;

Step S105: by described each vertical line and the length of anterior chamber's intersection and the quantity of described vertical line, calculate anterior chamber of the eye volume in described anterior chamber's image.

The method of determination anterior chamber of the eye volume provided by the present invention, by obtaining the original scan image of prosthomere OCT; The prosthomere OCT image of point anterior chambers such as default first quantity is chosen from original scan image; Prosthomere OCT image is shown, depicts anterior chamber's image; By presetting the vertical line of the 2nd quantity, anterior chamber's image is split, the length of each vertical line and anterior chamber's intersection in each several part of computation partition; By each vertical line and the length of anterior chamber's intersection and the quantity of vertical line, calculate anterior chamber of the eye volume in anterior chamber's image. The method of determination anterior chamber of the eye volume provided by the present invention, it is possible to overcome the deficiency of current anterior chamber's volumetric measurement, more accurately obtain anterior chamber's volume, can also save cost simultaneously, increases economic benefit.

On the basis of a upper embodiment, as a kind of preferred implementation, it is possible to get rid of error image when wrong and calculate, specifically, as shown in Figure 2, the method comprises the schema of another kind of embodiment of the method for determination anterior chamber of the eye volume provided by the present invention:

Step S201: the original scan image obtaining prosthomere OCT;

Step S202: remove the image that scanning is imperfect, chooses the prosthomere OCT image of certain (even number) quantity from the described original scan image that scanning is complete, and described prosthomere OCT image is the image of decile anterior chamber;

Step S203: described prosthomere OCT image is shown, depicts anterior chamber's image;

Step S204: described anterior chamber's image is split by the vertical line of predetermined number, the length of each vertical line and anterior chamber's intersection in each several part of computation partition;

Step S205: by the quantity of the length of described each vertical line and anterior chamber's intersection and point secant, calculate anterior chamber of the eye volume in described anterior chamber's image.

Due to the uncertain sweep trace number of the present invention, therefore the present embodiment is by deleting the imperfect sweep trace of scanning, and only retains correct scan image, then carries out subsequent operations, avoid the skew owing to scanning errors causes, thus further increase the accuracy rate of diagnosis and treatment.

For the quantity of decile anterior chamber as even number, below the method for determination anterior chamber of the eye volume provided by the present invention is further elaborated. Prosthomere OCT image is gathered by OCT, the image collected is imported in software Rhinocero, Manual description goes out anterior chamber's image, 2 horizontal linears are respectively drawn up and down anterior chamber, 2 end alignment angles, room, again with 201 vertical straight lines the straight line of these 2 levels etc. point 200 equal portions, such as Fig. 3 OCT image carried out shown in the schematic diagram split. Then the length of 201 straight lines and anterior chamber's intersection and the length of 200 equal portions is calculated. Recycling software Mathematica determines anterior chamber's volume by following formula.

$\begin{array}{c}\underset{i=0}{\overset{99}{\Σ}}\left(i+0.5\right){\∫}_0^{\frac{\mathrm{\π}}{2}}\sqrt{c^2{\sin }^2\mathrm{\θ}+d^2{\cos }^2\mathrm{\θ}}\\ \×\[\left(1-\frac{2\mathrm{\θ}}{\mathrm{\π}}\right)\left(a_{101-i}+a_{100-i}+a_{101+i}+a_{102+i}\right)+\frac{2\mathrm{\θ}}{\mathrm{\π}}\left(b_{101-i}+b_{100-i}+b_{101+i}+b_{102+i}\right)\]\×\[\left(1-\frac{2\mathrm{\θ}}{\mathrm{\π}}\right)c+\frac{2\mathrm{\θ}}{\mathrm{\π}}d\]d\mathrm{\θ}\end{array}$

In the present embodiment, adopt the orthogonal plane by eyeball center, the eyeball quartern is obtained two cross sections, by two cross sections along transverse axis direction 200 decile. By Along ent place from iris crystal front surface trace line to the distance of corneal endothelium trace line, it is called the height of trace line. The height of the trace line of one of them planar interception is designated asSpacing between Along ent is designated as c; The height of the trace line of another planar interception vertical with it is designated asSpacing between Along ent is designated as d.

Adopt single image to measure anterior chamber's volume method accuracy at present not high, and tomeyOCT is expensive, and multiple image measurements can be adopted, there will be measuring error when there being several orientation to have eyelid to block. For overcoming the defect of prior art, anterior chamber's method for measuring volume is improved by the present invention, the image of any amount can be taked to carry out Measurement accuracy, when wrong, remove error image simultaneously calculate, it is possible to be applicable to any equipment that can gather prosthomere image.

Below the device of determination anterior chamber of the eye volume that the embodiment of the present invention provides is introduced, described below determines with above-described, the device of anterior chamber of the eye volume determines that the method for anterior chamber of the eye volume can corresponding reference mutually. The structure block diagram of the device of the determination anterior chamber of the eye volume that Fig. 4 provides for the embodiment of the present invention, determine that the device of anterior chamber of the eye volume can comprise with reference to Fig. 4:

Acquisition module 100, for obtaining the original scan image of prosthomere OCT;

Choose module 200, for choosing the prosthomere OCT image of default first quantity from described original scan image, described prosthomere OCT image scanning position etc. point anterior chamber, described default first quantity is even number;

Display module 300, for being shown by described prosthomere OCT image, depicts anterior chamber's image;

Calculate module 400, for described anterior chamber's image being split by presetting the vertical line of the 2nd quantity, the length of each vertical line and anterior chamber's intersection in each several part of computation partition;

Determination module 500, for by the length of described each vertical line and anterior chamber's intersection and the quantity of described vertical line, calculating anterior chamber of the eye volume in described anterior chamber's image.

Can selection of land, above-mentioned choose module 200 specifically for:

Remove the image that scanning is imperfect, from the described original scan image that scanning is complete, choose the prosthomere OCT image of default first quantity.

Can selection of land, above-mentioned determination module 500 specifically for:

By in described each vertical line and the length of anterior chamber's intersection and the woods of described vertical line, according to

$\begin{array}{c}\underset{i=0}{\overset{99}{\Σ}}\left(i+0.5\right){\∫}_0^{\frac{\mathrm{\π}}{2}}\sqrt{c^2{\sin }^2\mathrm{\θ}+d^2{\cos }^2\mathrm{\θ}}\\ \×\[\left(1-\frac{2\mathrm{\θ}}{\mathrm{\π}}\right)\left(a_{101-i}+a_{100-i}+a_{101+i}+a_{102+i}\right)+\frac{2\mathrm{\θ}}{\mathrm{\π}}\left(b_{101-i}+b_{100-i}+b_{101+i}+b_{102+i}\right)\]\×\[\left(1-\frac{2\mathrm{\θ}}{\mathrm{\π}}\right)c+\frac{2\mathrm{\θ}}{\mathrm{\π}}d\]d\mathrm{\θ}\end{array}$

Determining the anterior chamber of the eye volume in described anterior chamber's image, parameter interpretation wherein is as follows: by two orthogonal planes, the eyeball quartern is obtained two cross sections, by two cross sections along transverse axis direction 200 decile. By Along ent place from iris crystal front surface trace line to the distance of corneal endothelium trace line, it is called the height of trace line. The height of the trace line of one of them planar interception is designated asSpacing between Along ent is designated as c; The height of the trace line of another planar interception vertical with it is designated asSpacing between Along ent is designated as d.

The device of determination anterior chamber of the eye volume provided by the present invention, by obtaining the original scan image of prosthomere OCT; The prosthomere OCT image of point anterior chambers such as certain (even number) quantity is chosen from original scan image; Prosthomere OCT image is shown, depicts anterior chamber's image; By the vertical line of predetermined number, anterior chamber's image is split, the length of each vertical line and anterior chamber's intersection in each several part of computation partition; By the quantity of the length of each vertical line and anterior chamber's intersection and point secant, calculate anterior chamber of the eye volume in anterior chamber's image. The device of determination anterior chamber of the eye volume provided by the present invention, it is possible to overcome the deficiency of current anterior chamber's volumetric measurement, more accurately obtain anterior chamber's volume, can also save cost simultaneously, increases economic benefit.

In this specification sheets, each embodiment adopts the mode gone forward one by one to describe, and what each embodiment emphasis illustrated is the difference with other embodiment, between each embodiment same or similar part mutually see.

To the above-mentioned explanation of the disclosed embodiments, professional and technical personnel in the field are enable to realize or use the present invention. To be apparent for those skilled in the art to the multiple amendment of these embodiments, General Principle as defined herein can without departing from the spirit or scope of the present invention, realize in other embodiments. Therefore, the present invention can not be limited in these embodiments shown in this article, but be met the widest scope consistent with principle disclosed herein and features of novelty.

Claims (6)

1. determine the method for anterior chamber of the eye volume for one kind, it is characterised in that, comprising:

Obtain the original scan image of prosthomere OCT;

Choosing the prosthomere OCT image of default first quantity from described original scan image, described prosthomere OCT image scanning position etc. point anterior chamber, described default first quantity is even number;

Described prosthomere OCT image is shown, depicts anterior chamber's image;

By presetting the vertical line of the 2nd quantity, described anterior chamber's image is split, the length of each vertical line and anterior chamber's intersection in each several part of computation partition;

By described each vertical line and the length of anterior chamber's intersection and the quantity of described vertical line, calculate anterior chamber of the eye volume in described anterior chamber's image.

2. determine the method for anterior chamber of the eye volume as claimed in claim 1, it is characterised in that, the described prosthomere OCT image choosing default first quantity from described original scan image comprises:

Remove the image that scanning is imperfect, from the described original scan image that scanning is complete, choose the prosthomere OCT image of default first quantity.

3. determine the method for anterior chamber of the eye volume as claimed in claim 1 or 2, it is characterised in that, described by described each vertical line and the length of anterior chamber's intersection and the quantity of described vertical line, calculate anterior chamber of the eye volume in described anterior chamber's image and comprise:

By described each vertical line and the length of anterior chamber's intersection and the quantity of described vertical line, according to:

$\begin{array}{c}\underset{i=0}{\overset{99}{\mathrm{\Σ}}}(i+0.5){\∫}_0^{\frac{\mathrm{\π}}{2}}\sqrt{c^2{\sin }^2\mathrm{\θ}+d^2{\cos }^2\mathrm{\θ}}\\ \×\[(1-\frac{2\mathrm{\θ}}{\mathrm{\π}})(a_{101-i}+a_{100-i}+a_{101+i}+a_{102+i})+\frac{2\mathrm{\θ}}{\mathrm{\π}}(b_{101-i}+b_{100-i}+b_{101+i}+b_{102+i})\]\×\[(1-\frac{2\mathrm{\θ}}{\mathrm{\π}})c+\frac{2\mathrm{\θ}}{\mathrm{\π}}d\]d\mathrm{\θ}\end{array}$

Calculate the anterior chamber of the eye volume in described anterior chamber's image; Parameter interpretation wherein is as follows: by two orthogonal planes, the eyeball quartern obtains two cross sections, by two cross sections along transverse axis direction 200 decile, by Along ent place from iris crystal front surface trace line to the distance of corneal endothelium trace line, the height being called trace line, the height of the trace line of one of them planar interception is designated asSpacing between Along ent is designated as c; The height of the trace line of another planar interception vertical with it is designated asSpacing between Along ent is designated as d.

4. determine the device of anterior chamber of the eye volume for one kind, it is characterised in that, comprising:

Acquisition module, for obtaining the original scan image of prosthomere OCT;

Choose module, for choosing the prosthomere OCT image of default first quantity from described original scan image, described prosthomere OCT image scanning position etc. point anterior chamber, described default first quantity is even number;

Display module, for being shown by described prosthomere OCT image, depicts anterior chamber's image;

Calculate module, for described anterior chamber's image being split by presetting the vertical line of the 2nd quantity, the length of each vertical line and anterior chamber's intersection in each several part of computation partition;

Determination module, for by the length of described each vertical line and anterior chamber's intersection and the quantity of described vertical line, calculating anterior chamber of the eye volume in described anterior chamber's image.

5. determine the device of anterior chamber of the eye volume as claimed in claim 4, it is characterised in that, described in choose module specifically for:

Remove the image that scanning is imperfect, from the described original scan image that scanning is complete, choose the prosthomere OCT image of default first quantity.

6. the device of determination anterior chamber of the eye volume as described in claim 4 or 5, it is characterised in that, described determination module specifically for:

By described each vertical line and the length of anterior chamber's intersection and the quantity of described vertical line, according to

$\begin{array}{c}\underset{i=0}{\overset{99}{\mathrm{\Σ}}}(i+0.5){\∫}_0^{\frac{\mathrm{\π}}{2}}\sqrt{c^2{\sin }^2\mathrm{\θ}+d^2{\cos }^2\mathrm{\θ}}\\ \×\[(1-\frac{2\mathrm{\θ}}{\mathrm{\π}})(a_{101-i}+a_{100-i}+a_{101+i}+a_{102+i})+\frac{2\mathrm{\θ}}{\mathrm{\π}}(b_{101-i}+b_{100-i}+b_{101+i}+b_{102+i})\]\×\[(1-\frac{2\mathrm{\θ}}{\mathrm{\π}})c+\frac{2\mathrm{\θ}}{\mathrm{\π}}d\]d\mathrm{\θ}\end{array}$

Calculate the anterior chamber of the eye volume in described anterior chamber's image, parameter interpretation wherein is as follows: by two orthogonal planes, the eyeball quartern obtains two cross sections, by two cross sections along transverse axis direction 200 decile, by Along ent place from iris crystal front surface trace line to the distance of corneal endothelium trace line, the height being called trace line, the height of the trace line of one of them planar interception is designated asSpacing between Along ent is designated as c; The height of the trace line of another planar interception vertical with it is designated asSpacing between Along ent is designated as d.