JP2014198224A5 - - Google Patents

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JP2014198224A5
JP2014198224A5 JP2013097732A JP2013097732A JP2014198224A5 JP 2014198224 A5 JP2014198224 A5 JP 2014198224A5 JP 2013097732 A JP2013097732 A JP 2013097732A JP 2013097732 A JP2013097732 A JP 2013097732A JP 2014198224 A5 JP2014198224 A5 JP 2014198224A5
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本画像処理装置は、 被検眼による収差が補正された画像である第1眼底画像と前記第1眼底画像よりも画角が広くかつ解像度が低い第2眼底画像との位置合わせを前記第2眼底画像よりも画角が狭くかつ解像度が高く更に前記第1眼底画像よりも画角が広くかつ解像度が低い第3眼底画像を用いて行う位置合わせ手段と、前記被検眼の黄斑から前記位置合わせ手段により位置合わせされた前記第1眼底画像における所定の位置までの距離を取得する距離取得手段と、前記距離と前記第1眼底画像に含まれる視細胞に関する情報とから前記被検眼の状態を評価する評価手段とを備える。 The image processing apparatus aligns the first fundus image, which is an image in which aberrations due to the subject's eye are corrected, and the second fundus image having a wider angle of view and lower resolution than the first fundus image. and line intends alignment means using the third fundus image has low wide and resolution angle than a narrow angle of view and further resolution is rather high the first fundus image than the image, the macular of the eye to be examined The state of the eye to be examined from distance acquisition means for acquiring a distance to a predetermined position in the first fundus image aligned by the alignment means, and information on the photoreceptor cells contained in the distance and the first fundus image And evaluation means for evaluating.

Claims (21)

被検眼による収差が補正された画像である第1眼底画像と前記第1眼底画像よりも画角が広くかつ解像度が低い第2眼底画像との位置合わせを前記第2眼底画像よりも画角が狭くかつ解像度が高く更に前記第1眼底画像よりも画角が広くかつ解像度が低い第3眼底画像を用いて行う位置合わせ手段と、
前記被検眼の黄斑から前記位置合わせ手段により位置合わせされた前記第1眼底画像における所定の位置までの距離を取得する距離取得手段と、
前記距離と前記第1眼底画像に含まれる視細胞に関する情報とから前記被検眼の状態を評価する評価手段とを備えたことを特徴とする画像処理装置。
The first fundus image, which is an image in which the aberration due to the subject's eye is corrected, and the second fundus image having a wider angle of view and lower resolution than the first fundus image are aligned with each other. narrow and the row intends alignment means using the third fundus image angle than further the first fundus image resolution rather high, wide and resolution have low,
Distance acquisition means for acquiring a distance from the macular of the subject eye to a predetermined position in the first fundus image aligned by the alignment means;
An image processing apparatus comprising: an evaluation unit that evaluates the state of the eye to be examined from the distance and information on photoreceptor cells included in the first fundus image.
前記位置合わせ手段は、前記第2眼底画像と前記第3眼底画像との位置合わせ結果と、前記第3眼底画像と前記第1眼底画像との位置合わせ結果と、に基づいて前記第1眼底画像と前記第2眼底画像との位置合わせを行うことを特徴とする請求項1記載の画像処理装置。   The alignment means is configured to determine the first fundus image based on the alignment result between the second fundus image and the third fundus image and the alignment result between the third fundus image and the first fundus image. The image processing apparatus according to claim 1, wherein alignment between the image and the second fundus image is performed. 前記第1眼底画像に対して領域を設定する設定手段を更に備え、
前記距離取得手段は前記黄斑の位置から前記領域内の所定の位置までの距離を取得し、
前記評価手段は、前記領域内の所定の位置までの距離と前記領域における視細胞に関する情報とから前記被検眼の状態を評価することを特徴とする請求項1または請求項2に記載の画像処理装置。
Setting means for setting an area for the first fundus image;
The distance acquisition means acquires a distance from the position of the macula to a predetermined position in the region,
3. The image processing according to claim 1, wherein the evaluation unit evaluates the state of the eye to be examined from a distance to a predetermined position in the region and information relating to a photoreceptor cell in the region. apparatus.
前記設定手段は前記第1眼底画像と前記黄斑との位置関係に応じて前記領域の設定方法を変更することを特徴とする請求項3記載の画像処理装置。   The image processing apparatus according to claim 3, wherein the setting unit changes a setting method of the region according to a positional relationship between the first fundus image and the macula. 前記設定手段は、前記第1眼底画像と前記黄斑とを結ぶ直線に垂直な方向における幅が前記直線に平行な方向における幅よりも大きくなるように前記領域を設定することを特徴とする請求項4記載の画像処理装置。   The setting means sets the region so that a width in a direction perpendicular to a straight line connecting the first fundus image and the macula is larger than a width in a direction parallel to the straight line. 4. The image processing apparatus according to 4. 前記設定手段は、前記第1眼底画像に含まれる血管領域を含まないように前記領域を設定することを特徴とする請求項3〜5のいずれか1項に記載の画像処理装置。   The image processing apparatus according to claim 3, wherein the setting unit sets the region so as not to include a blood vessel region included in the first fundus image. 前記所定の位置は、前記領域の中心であること特徴とする請求項3〜6のいずれか1項に記載の画像処理装置。   The image processing apparatus according to claim 3, wherein the predetermined position is a center of the region. 前記視細胞に関する情報は前記視細胞の密度であることを特徴とする請求項1〜7のいずれか1項に記載の画像処理装置。   The image processing apparatus according to claim 1, wherein the information on the photoreceptor cell is a density of the photoreceptor cell. 前記第1眼底画像から前記視細胞を検出する検出手段を更に備え、
前記検出手段は、前記距離取得手段により取得された前記距離に応じて、前記視細胞を検出するために用いるパラメタを変更することを特徴とする請求項1〜8のいずれか1項に記載の画像処理装置。
A detection means for detecting the photoreceptor cells from the first fundus image;
The said detection means changes the parameter used in order to detect the said photoreceptor cell according to the said distance acquired by the said distance acquisition means, The any one of Claims 1-8 characterized by the above-mentioned. Image processing device.
前記評価手段は、前記視細胞に関する情報と前記距離に応じた基準情報とを比較することを特徴とする請求項1〜9のいずれか1項に記載の画像処理装置。   The image processing apparatus according to claim 1, wherein the evaluation unit compares information relating to the photoreceptor cell with reference information corresponding to the distance. 前記比較の結果に基づく表示形態で前記第1眼底画像を表示部に表示させる表示制御手段を備えたことを特徴とする請求項10記載の画像処理装置。   The image processing apparatus according to claim 10, further comprising display control means for displaying the first fundus image on a display unit in a display form based on the comparison result. 前記表示制御手段が、前記視細胞に関する情報と前記距離に応じた基準情報との差に応じて前記第1眼底画像の明度を変えることを特徴とする請求項11に記載の画像処理装置。   The image processing apparatus according to claim 11, wherein the display control unit changes the brightness of the first fundus image according to a difference between information relating to the photoreceptor cell and reference information corresponding to the distance. 前記表示制御手段が、前記視細胞に関する情報と前記距離に応じた基準情報との差が所定値以上となる前記第1眼底画像上の領域の面積を提示することを特徴とする請求項12に記載の画像処理装置。   The display control means presents an area of a region on the first fundus image in which a difference between information relating to the photoreceptor cell and reference information corresponding to the distance is a predetermined value or more. The image processing apparatus described. 前記表示制御手段が、前記位置合わせ手段により位置合わせが行われた前記第1画像と前記第2画像とを前記表示部に重畳表示させることを特徴とする請求項11〜13のいずれか1項に記載の画像処理装置。   14. The display control unit according to any one of claims 11 to 13, wherein the display control unit superimposes the first image and the second image that have been aligned by the alignment unit on the display unit. An image processing apparatus according to 1. 前記位置合わせ手段による位置合わせの際に、解像度が高い画像を解像度が低い画像と同じ解像度に変換する解像度変換手段を更にそなえ、
前記位置合わせ手段は、前記解像度変換後の画像を用いて位置合わせを行うことを特徴とする請求項1〜14のいずれか1項に記載の画像処理装置。
A resolution converting means for converting an image having a high resolution into the same resolution as an image having a low resolution at the time of positioning by the positioning means;
The image processing apparatus according to claim 1, wherein the alignment unit performs alignment using the image after the resolution conversion.
黄班を検出する検出手段を更に備え、
前記位置合わせ手段は、前記被検眼の眼底上の異なる位置を撮像した複数の前記第1眼底画像と前記第2眼底画像とを前記眼底上の異なる位置を撮像した複数の前記第3眼底画像を用いて位置合わせを行い、
前記検出手段は、前記位置合わせ手段により位置合わせされた前記複数の前記第1眼底画像のうち前記黄班を含む前記第1眼底画像から前記黄班を検出し、
前記距離取得手段は、前記検出手段により検出された前記黄斑から前記位置合わせ手段により位置合わせされた前記複数の前記第1眼底画像のうち前記黄班を含まない前記第1眼底画像における所定の位置までの距離を取得することを特徴とする請求項1記載の画像処理装置。
It further comprises a detecting means for detecting a macula,
The positioning means includes a plurality of the first fundus images obtained by imaging different positions on the fundus of the eye to be examined and the second fundus images obtained by imaging the plurality of third fundus images obtained by imaging different positions on the fundus. Use to align,
The detection means detects the macula from the first fundus image including the macula among the plurality of first fundus images aligned by the alignment means,
The distance acquisition unit includes a predetermined position in the first fundus image that does not include the macula among the plurality of first fundus images aligned by the alignment unit from the macula detected by the detection unit. The image processing apparatus according to claim 1, wherein a distance up to is acquired.
前記距離取得手段は、前記黄班中心から前記第1眼底画像における所定の位置までの距離を取得することを特徴とする請求項1記載の画像処理装置。   The image processing apparatus according to claim 1, wherein the distance acquisition unit acquires a distance from the center of the macula to a predetermined position in the first fundus image. 位置合わせ手段が、被検眼による収差が補正された画像である第1眼底画像と前記第1眼底画像よりも画角が広くかつ解像度が低い第2眼底画像との位置合わせを前記第2眼底画像よりも画角が狭くかつ解像度が高く更に前記第1眼底画像よりも画角が広くかつ解像度が低い第3眼底画像を用いて行う位置合わせ工程と、
距離取得手段が、前記被検眼の黄斑から前記位置合わせ手段により位置合わせされた前記第1眼底画像における所定の位置までの距離を取得する距離取得工程と、
評価手段が、前記距離と前記第1眼底画像に含まれる視細胞に関する情報とから前記被検眼の状態を評価する評価工程とを備えたことを特徴とする画像処理方法。
The second fundus image is obtained by aligning the first fundus image, which is an image in which the aberration caused by the eye to be corrected is corrected, and the second fundus image having a wider angle of view and lower resolution than the first fundus image. a positioning process intends line using a third fundus image viewing angle is wide and the resolution have lower than high rather further the first fundus image is narrow and resolution angle than,
A distance acquisition step of acquiring a distance from the macular of the eye to be examined to a predetermined position in the first fundus image aligned by the alignment unit;
An image processing method, comprising: an evaluation unit that evaluates a state of the eye to be examined from the distance and information relating to a photoreceptor cell included in the first fundus image.
請求項18記載の各工程をコンピュータに実行させるためのプログラム。   The program for making a computer perform each process of Claim 18. 被検眼による収差が補正された画像である第1眼底画像と前記第1眼底画像よりも画角が広くかつ解像度が低い第2眼底画像と前記第2眼底画像よりも画角が狭くかつ解像度が高く更に前記第1眼底画像よりも画角が広くかつ解像度が低い第3眼底画像とを取得する取得手段と、A first fundus image, which is an image in which aberrations due to the subject's eye are corrected, a second fundus image having a wider angle of view and lower resolution than the first fundus image, and a smaller angle of view and resolution than the second fundus image. Acquisition means for acquiring a third fundus image that is higher and has a wider angle of view and lower resolution than the first fundus image;
前記第3眼底画像を用いて前記第1眼底画像と前記第2眼底画像との位置合わせを行う位置合わせ手段と、Alignment means for performing alignment between the first fundus image and the second fundus image using the third fundus image;
を備えたことを特徴とする画像処理装置。An image processing apparatus comprising:
前記位置合わせ手段は、前記第2眼底画像と前記第3眼底画像との位置合わせ結果と、前記第3眼底画像と前記第1眼底画像との位置合わせ結果と、に基づいて前記第1眼底画像と前記第2眼底画像との位置合わせを行うことを特徴とする請求項20記載の画像処理装置。The alignment means is configured to determine the first fundus image based on the alignment result between the second fundus image and the third fundus image and the alignment result between the third fundus image and the first fundus image. 21. The image processing apparatus according to claim 20, wherein the image is aligned with the second fundus image.
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