CN105623918A - Low-foam multienzyme cleaning agent - Google Patents

Low-foam multienzyme cleaning agent Download PDF

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Publication number
CN105623918A
CN105623918A CN201610094172.9A CN201610094172A CN105623918A CN 105623918 A CN105623918 A CN 105623918A CN 201610094172 A CN201610094172 A CN 201610094172A CN 105623918 A CN105623918 A CN 105623918A
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parts
cleaning agent
multienzyme cleaning
enzyme
multienzyme
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CN201610094172.9A
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Chinese (zh)
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孙宁
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    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/0005Other compounding ingredients characterised by their effect
    • C11D3/0026Low foaming or foam regulating compositions
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/38Products with no well-defined composition, e.g. natural products
    • C11D3/386Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38627Preparations containing enzymes, e.g. protease or amylase containing lipase
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/38Products with no well-defined composition, e.g. natural products
    • C11D3/386Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38645Preparations containing enzymes, e.g. protease or amylase containing cellulase
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/38Products with no well-defined composition, e.g. natural products
    • C11D3/386Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38663Stabilised liquid enzyme compositions
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D7/00Compositions of detergents based essentially on non-surface-active compounds
    • C11D7/02Inorganic compounds
    • C11D7/04Water-soluble compounds
    • C11D7/08Acids
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D7/00Compositions of detergents based essentially on non-surface-active compounds
    • C11D7/22Organic compounds
    • C11D7/26Organic compounds containing oxygen
    • C11D7/261Alcohols; Phenols
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D7/00Compositions of detergents based essentially on non-surface-active compounds
    • C11D7/22Organic compounds
    • C11D7/26Organic compounds containing oxygen
    • C11D7/265Carboxylic acids or salts thereof
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D7/00Compositions of detergents based essentially on non-surface-active compounds
    • C11D7/22Organic compounds
    • C11D7/26Organic compounds containing oxygen
    • C11D7/268Carbohydrates or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D7/00Compositions of detergents based essentially on non-surface-active compounds
    • C11D7/22Organic compounds
    • C11D7/32Organic compounds containing nitrogen
    • C11D7/3218Alkanolamines or alkanolimines
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D7/00Compositions of detergents based essentially on non-surface-active compounds
    • C11D7/22Organic compounds
    • C11D7/32Organic compounds containing nitrogen
    • C11D7/3245Aminoacids

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Detergent Compositions (AREA)

Abstract

The invention discloses a low-foam multienzyme cleaning agent.The low-foam multienzyme cleaning agent is prepared from, by weight, 5-20 parts of polyethylene glycol, 5-15 parts of isopropanol, 5-10 parts of an enzyme compound stabilizer, 3-6 parts of a neutral proteolytic enzyme, 3-6 parts of marine organism protease, 2-4 parts of lipase, 1-2 parts of amylase, 0.5-1 part of neutral cellulase, 1-3 parts of lysozyme, 0.5-5 parts of mycose, 0.1-0.5 part of a preservative, 3-6 parts of a chelating agent and 100 parts of deionized water.The low-foam multienzyme cleaning agent has the advantages that the multienzyme cleaning agent can remove biological membranes on the surfaces of devices, the surface brightness of the cleaned devices is good, no residual spot exists, and the multienzyme cleaning agent is suitable for full-automatic spraying cleaning machines or ultrasonic medical cleaning equipment; the low-foam multienzyme cleaning agent is added with ingredients such as the enzyme compound stabilizer, and thus the enzymatic activity in the multienzyme cleaning agent is effectively prolonged.

Description

A kind of low bubble multienzyme cleaning agent
Technical field
The invention belongs to the cleaning and sterilizing technical field of medical apparatus and instruments, be specifically related to a kind of low bubble multienzyme cleaning agent.
Background technology
It is known that, medical apparatus and instruments in use can be infected with the dirts such as blood, mucosal tissue or greasy dirt, if cleaning thorough not, can cause that serious pathogenic bacteria grows or pollute corrosion drawback, thus bringing the service life threatening and reducing equipment to the healthy of people. Chemical traditional in the market is common also exists the problems such as consumption is big, pollute greatly, cleaning is not thorough, and medical apparatus and instruments has corrosivity, causes that automatic rinser is easily damaged.
And it has been discovered that some enzyme has the ability of good decomposing pollutant, its mechanism is in that these enzyme can react with greasy dirt or pollutant, thus decomposing to fall by pollutant.
Patent CN104073367A discloses a kind of Multi-enzyme detergent being applicable to machine washing medical apparatus and instruments and preparation method thereof, the mass percent of its dispensing is composed as follows: water 77-89%, protease 2-4%, lipase 1-3%, amylase 1-2% are or/and cellulase 0.5-2%, low bubble efficient surfactant 1-2%, antibacterial 0.5-1% and chelating agen 2-5% etc., and collectively constituting component is 100%. Wherein play decomposition and be mainly various enzyme, yet with the other biological enzyme in protease energy decomposing solution, cause that the bioenzyme activity in abluent is low.
Summary of the invention
The present invention is directed to the low problem of the bioenzyme activity in the multienzyme cleaning agent existed in background technology and a kind of low bubble multienzyme cleaning agent is provided.
The technical scheme realizing the object of the invention is: a kind of low bubble multienzyme cleaning agent, this low bubble multienzyme cleaning agent, consists of by weight: Polyethylene Glycol 5��20 parts, isopropanol 5��15 parts, enzyme combining stabilizer 5��10 parts, neutral water proteolytic enzyme 3��6 parts, marine protein enzyme 3��6 parts, lipase 2��4 parts, amylase 1��2 part, neutral cellulase 0.5��1 part, lysozyme 1��3 part, trehalose 0.5��5 part, preservative 0.1��0.5 part, deionized water 100 parts.
As a modification of the present invention, described enzyme combining stabilizer, composed as follows by weight: triethanolamine 5��15 parts, boric acid 5��15 parts, sucrose 5��15 parts, sodium carboxymethyl cellulose 1��5 part, deionized water 100 parts.
Preferably, described enzyme combining stabilizer is prepared by following methods step: 1) be dissolved in deionized water by sodium carboxymethyl cellulose, triethanolamine and sucrose, prepares the first dispersion liquid; 2) boric acid is dissolved in ionized water, prepares the second dispersion liquid; 3) the second dispersion liquid is slowly added dropwise in the first dispersion liquid, stirs.
It is furthermore preferred that described chelating agen is sodium citrate or EDTA-4Na, described preservative is biological preparation nisin.
Especially, low bubble multienzyme cleaning agent of the present invention, following method step prepare: 1) add Polyethylene Glycol, chelating agen, preservative and enzyme combining stabilizer in deionized water, stir, prepare the first mixed liquor; 2) in isopropanol, it is sequentially added into neutral water proteolytic enzyme, marine protein enzyme, stirs, prepare the second mixed liquor; 3) the second mixed liquor is added in the first mixed liquor, stir 10��30 minutes, then be sequentially added into lipase, amylase, neutral cellulase and lysozyme in order, stir 10��30 minutes, be eventually adding trehalose and continue stirring 10��30 minutes.
Compared with prior art, the technological merit of the present invention is in that:
1) the low bubble multienzyme cleaning agent of the present invention does not contain surfactant, effectively reduces chemical substance residual on apparatus, and the alcohols material in formula and liquid enzymes are by, after suitable proportioning, making Multi-enzyme detergent reach a kind of intimate still state. The multienzyme cleaning agent of the present invention can remove apparatus surface biological film, equipment surfaces good brightness, noresidue speckle after cleaning, it is adaptable to fully-automatic sprinkling cleaning machine or ultrasound medical cleaning equipment.
2) the low bubble multienzyme cleaning agent of the present invention with the addition of the compositions such as enzyme combining stabilizer, effectively extends enzymatic activity in multienzyme cleaning agent, and the enzyme liquid after multienzyme cleaning agent dilution can preserve 18h, and the enzymatic activity of tradition enzyme cleanout fluid inactivates at about 4h.
3) the low bubble multienzyme cleaning agent of the present invention with the addition of lysozyme so that multienzyme cleaning agent has quickly makes virally inactivated pharmacological action, and enzyme liquid is served good protective effect by the trehalose additionally added.
4) preservative that the present invention adds is biological preparation nisin, has the advantages such as safe and environment-friendly compared with common chemically composited preservative.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further described through.
Low bubble multienzyme cleaning agent of the present invention, is prepared by following method step: 1) add Polyethylene Glycol, chelating agen, preservative and enzyme combining stabilizer in deionized water, stir, prepare the first mixed liquor; 2) in isopropanol, it is sequentially added into neutral water proteolytic enzyme, marine protein enzyme, stirs, prepare the second mixed liquor; 3) the second mixed liquor is added in the first mixed liquor, stir 10��30 minutes, then be sequentially added into lipase, amylase, neutral cellulase and lysozyme in order, stir 10��30 minutes, be eventually adding trehalose and continue stirring 10��30 minutes.
Wherein, described enzyme combining stabilizer is prepared by following methods step: 1) be dissolved in deionized water by sodium carboxymethyl cellulose, triethanolamine and sucrose, prepares the first dispersion liquid; 2) boric acid is dissolved in ionized water, prepares the second dispersion liquid; 3) the second dispersion liquid is slowly added dropwise in the first dispersion liquid, stirs.
Embodiment 1
1) the formula composition of enzyme combining stabilizer
Composed as follows by weight: triethanolamine 5 parts, boric acid 10 parts, sucrose 15 parts, sodium carboxymethyl cellulose 3 parts, deionized water 100 parts.
2) the formula composition of low bubble multienzyme cleaning agent
Composed as follows by weight: Polyethylene Glycol 5 parts, isopropanol 15 parts, enzyme combining stabilizer 10 parts, neutral water proteolytic enzyme 5 parts, marine protein enzyme 4 parts, lipase 2 parts, amylase 1 part, neutral cellulase 1 part, lysozyme 3 parts, trehalose 5 parts, biological preparation nisin 0.3 part, sodium citrate 4 parts, deionized water 100 parts.
Embodiment 2
1) the formula composition of enzyme combining stabilizer
Composed as follows by weight: triethanolamine 10 parts, boric acid 15 parts, sucrose 5 parts, sodium carboxymethyl cellulose 1 part, deionized water 100 parts.
2) the formula composition of low bubble multienzyme cleaning agent
Composed as follows by weight: Polyethylene Glycol 15 parts, isopropanol 10 parts, enzyme combining stabilizer 5 parts, neutral water proteolytic enzyme 3 parts, marine protein enzyme 6 parts, lipase 3 parts, amylase 1.5 parts, neutral cellulase 0.8 part, lysozyme 2 parts, trehalose 3 parts, biological preparation nisin 0.1 part, sodium citrate 6 parts, deionized water 100 parts.
Embodiment 3
1) the formula composition of enzyme combining stabilizer
Composed as follows by weight: triethanolamine 15 parts, boric acid 5 parts, sucrose 10 parts, sodium carboxymethyl cellulose 5 parts, deionized water 100 parts.
2) the formula composition of low bubble multienzyme cleaning agent
Composed as follows by weight: Polyethylene Glycol 20 parts, isopropanol 5 parts, enzyme combining stabilizer 8 parts, neutral water proteolytic enzyme 6 parts, marine protein enzyme 3 parts, lipase 4 parts, amylase 2 part, neutral cellulase 0.5 part, lysozyme 1 part, trehalose 0.5 part, biological preparation nisin 0.5 part, sodium citrate 3 parts, deionized water 100 parts.
The low bubble multienzyme cleaning agent of the present invention with the addition of the compositions such as enzyme combining stabilizer, effectively extends enzymatic activity in multienzyme cleaning agent, and the enzyme liquid after multienzyme cleaning agent dilution can preserve 18h, and the enzymatic activity of tradition enzyme cleanout fluid inactivates at about 4h.

Claims (6)

1. one kind low bubble multienzyme cleaning agent, it is characterized in that: described low bubble multienzyme cleaning agent, consist of by weight: Polyethylene Glycol 5��20 parts, isopropanol 5��15 parts, enzyme combining stabilizer 5��10 parts, neutral water proteolytic enzyme 3��6 parts, marine protein enzyme 3��6 parts, lipase 2��4 parts, amylase 1��2 part, neutral cellulase 0.5��1 part, lysozyme 1��3 part, trehalose 0.5��5 part, preservative 0.1��0.5 part, chelating agen 3��6, deionized water 100 parts.
2. the low bubble multienzyme cleaning agent of one according to claim 1, it is characterized in that: described enzyme combining stabilizer, composed as follows by weight: triethanolamine 5��15 parts, boric acid 5��15 parts, sucrose 5��15 parts, sodium carboxymethyl cellulose 1��5 part, deionized water 100 parts.
3. the low bubble multienzyme cleaning agent of one according to claim 2, it is characterised in that: described enzyme combining stabilizer is prepared by following methods step: 1) be dissolved in deionized water by sodium carboxymethyl cellulose, triethanolamine and sucrose, prepares the first dispersion liquid; 2) boric acid is dissolved in ionized water, prepares the second dispersion liquid; 3) the second dispersion liquid is slowly added dropwise in the first dispersion liquid, stirs.
4. the low bubble multienzyme cleaning agent of one according to claim 1, it is characterised in that: described chelating agen is sodium citrate or EDTA-4Na.
5. the low bubble multienzyme cleaning agent of one according to claim 1, it is characterised in that: described preservative is biological preparation nisin.
6. the low bubble multienzyme cleaning agent of one according to claim 1, it is characterized in that: described low bubble multienzyme cleaning agent, prepared by following method step: 1) add Polyethylene Glycol, chelating agen, preservative and enzyme combining stabilizer in deionized water, stir, prepare the first mixed liquor; 2) in isopropanol, it is sequentially added into neutral water proteolytic enzyme, marine protein enzyme, stirs, prepare the second mixed liquor; 3) the second mixed liquor is added in the first mixed liquor, stir 10��30 minutes, then be sequentially added into lipase, amylase, neutral cellulase and lysozyme in order, stir 10��30 minutes, be eventually adding trehalose and continue stirring 10��30 minutes.
CN201610094172.9A 2016-02-22 2016-02-22 Low-foam multienzyme cleaning agent Pending CN105623918A (en)

Priority Applications (1)

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Application Number Priority Date Filing Date Title
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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106190603A (en) * 2016-07-11 2016-12-07 南京医科大学第附属医院 A kind of medical apparatus and instruments multienzyme cleaning agent containing natural bacteriostatic agent
CN108998289A (en) * 2018-09-26 2018-12-14 武汉新华扬生物股份有限公司 Enzyme stabilizers, Recompounded pesticide hydrolysis enzyme solution and preparation method thereof and fruits and vegetables cleaning solution and preparation method thereof
CN110194996A (en) * 2019-07-03 2019-09-03 韶关学院 A kind of food borne bacteria biofilm scavenger and its application
CN111394196A (en) * 2020-04-12 2020-07-10 长沙汇泉环境科技有限公司 Stone stain cleaning agent and preparation method thereof
CN112778991A (en) * 2021-01-08 2021-05-11 中国石油天然气集团公司 Biological enzyme composite blocking remover and preparation method thereof
CN115322846A (en) * 2022-08-23 2022-11-11 广西电网有限责任公司钦州供电局 Multienzyme-containing cleaning agent for cleaning biological membrane and production method thereof
CN115445443A (en) * 2022-10-20 2022-12-09 杭州佳嘉乐生物技术有限公司 Enzyme cleaning agent of ultrafiltration nanofiltration membrane for orlistat production and application thereof
CN116286209A (en) * 2021-12-20 2023-06-23 深圳市友创生物科技有限公司 Multienzyme low-foam medical instrument cleaning agent and preparation method thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101440361A (en) * 2007-11-22 2009-05-27 珠海百康生物技术有限公司 Method for preparing stable coated granzyme
CN101463291A (en) * 2007-12-18 2009-06-24 李萍 Marine organism antibacterial sterilizing washing liquid
CN102453631A (en) * 2010-11-02 2012-05-16 郑州大学 Medical liquid multienzyme detergent
CN104073367A (en) * 2013-12-05 2014-10-01 成都老肯科技股份有限公司 Multienzyme cleaning solution suitable for machine-washable medical devices and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101440361A (en) * 2007-11-22 2009-05-27 珠海百康生物技术有限公司 Method for preparing stable coated granzyme
CN101463291A (en) * 2007-12-18 2009-06-24 李萍 Marine organism antibacterial sterilizing washing liquid
CN102453631A (en) * 2010-11-02 2012-05-16 郑州大学 Medical liquid multienzyme detergent
CN104073367A (en) * 2013-12-05 2014-10-01 成都老肯科技股份有限公司 Multienzyme cleaning solution suitable for machine-washable medical devices and preparation method thereof

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106190603A (en) * 2016-07-11 2016-12-07 南京医科大学第附属医院 A kind of medical apparatus and instruments multienzyme cleaning agent containing natural bacteriostatic agent
CN108998289A (en) * 2018-09-26 2018-12-14 武汉新华扬生物股份有限公司 Enzyme stabilizers, Recompounded pesticide hydrolysis enzyme solution and preparation method thereof and fruits and vegetables cleaning solution and preparation method thereof
CN110194996A (en) * 2019-07-03 2019-09-03 韶关学院 A kind of food borne bacteria biofilm scavenger and its application
CN111394196A (en) * 2020-04-12 2020-07-10 长沙汇泉环境科技有限公司 Stone stain cleaning agent and preparation method thereof
CN112778991A (en) * 2021-01-08 2021-05-11 中国石油天然气集团公司 Biological enzyme composite blocking remover and preparation method thereof
CN112778991B (en) * 2021-01-08 2022-12-06 中国石油天然气集团公司 Biological enzyme composite blocking remover and preparation method thereof
CN116286209A (en) * 2021-12-20 2023-06-23 深圳市友创生物科技有限公司 Multienzyme low-foam medical instrument cleaning agent and preparation method thereof
CN115322846A (en) * 2022-08-23 2022-11-11 广西电网有限责任公司钦州供电局 Multienzyme-containing cleaning agent for cleaning biological membrane and production method thereof
CN115445443A (en) * 2022-10-20 2022-12-09 杭州佳嘉乐生物技术有限公司 Enzyme cleaning agent of ultrafiltration nanofiltration membrane for orlistat production and application thereof
CN115445443B (en) * 2022-10-20 2023-11-14 杭州佳嘉乐生物技术有限公司 Enzyme cleaning agent for ultrafiltration nanofiltration membrane for orlistat production and application thereof

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