CN105611910A - 包含胆汁酸-脂肪酸缀合物的抗老化组合物 - Google Patents

包含胆汁酸-脂肪酸缀合物的抗老化组合物 Download PDF

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Publication number
CN105611910A
CN105611910A CN201480055618.6A CN201480055618A CN105611910A CN 105611910 A CN105611910 A CN 105611910A CN 201480055618 A CN201480055618 A CN 201480055618A CN 105611910 A CN105611910 A CN 105611910A
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CN
China
Prior art keywords
acid
skin
composition
fabac
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201480055618.6A
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English (en)
Chinese (zh)
Inventor
纳瓦·达扬
艾伦·巴哈拉夫
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Galmed Research and Development Ltd
Original Assignee
GALDERM THERAPEUTICS Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GALDERM THERAPEUTICS Ltd filed Critical GALDERM THERAPEUTICS Ltd
Publication of CN105611910A publication Critical patent/CN105611910A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63—Steroids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A61K2800/522—Antioxidants; Radical scavengers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CN201480055618.6A 2013-08-08 2014-08-07 包含胆汁酸-脂肪酸缀合物的抗老化组合物 Pending CN105611910A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IL227890 2013-08-08
IL227890A IL227890A0 (en) 2013-08-08 2013-08-08 Antiaging compounds containing bile acid and fatty acid conjugates
PCT/IL2014/050717 WO2015019358A1 (en) 2013-08-08 2014-08-07 Anti-aging compositions comprising bile acid-fatty acid conjugates

Publications (1)

Publication Number Publication Date
CN105611910A true CN105611910A (zh) 2016-05-25

Family

ID=50022996

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201480055618.6A Pending CN105611910A (zh) 2013-08-08 2014-08-07 包含胆汁酸-脂肪酸缀合物的抗老化组合物

Country Status (9)

Country Link
US (1) US20160175223A1 (enExample)
EP (1) EP3030221A4 (enExample)
JP (1) JP2016527306A (enExample)
CN (1) CN105611910A (enExample)
AU (1) AU2014304078A1 (enExample)
CA (1) CA2920456A1 (enExample)
HK (1) HK1224198A1 (enExample)
IL (2) IL227890A0 (enExample)
WO (1) WO2015019358A1 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109503693A (zh) * 2018-12-12 2019-03-22 合肥工业大学 一种利用胆酸和花生酸为原料高效合成Aramchol的新工艺
CN116236490A (zh) * 2023-02-14 2023-06-09 四川大学 脱氧胆酸的用途及药物
WO2024012317A1 (zh) * 2022-07-14 2024-01-18 爱医谷(苏州)生物科技有限公司 一种用于抵抗衰老的组合物及其用途或方法

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2014304079A1 (en) * 2013-08-08 2016-02-25 Galmed Research & Development Ltd. Anti-acne compositions comprising bile acid-fatty acid conjugates
US11571431B2 (en) 2013-12-04 2023-02-07 Galmed Research And Development Ltd Aramchol salts
WO2016127102A2 (en) 2015-02-06 2016-08-11 Ernesto Abel-Santos Inhibiting germination of clostridium perfringens spores to reduce necrotic enteritis
US10849911B2 (en) 2015-06-10 2020-12-01 Galmed Research And Development Ltd. Low dose compositions of Aramachol salts
IL243707A0 (en) 2016-01-20 2016-05-01 Galmed Res And Dev Ltd Treatment to regulate the microbiota in the intestine
US11197870B2 (en) 2016-11-10 2021-12-14 Galmed Research And Development Ltd Treatment for hepatic fibrosis
JP2021100925A (ja) * 2019-10-31 2021-07-08 共栄化学工業株式会社 皮膚外用剤
JP2024525832A (ja) * 2021-07-16 2024-07-12 スカイ・セラピューティクス・カンパニー・リミテッド 胆汁酸又は胆汁酸塩の分子会合体を含む化粧料組成物
WO2023039159A2 (en) * 2021-09-09 2023-03-16 Abel Santos Ernesto Inhibitors of c. difficile spore germination

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4115313A (en) * 1974-10-08 1978-09-19 Irving Lyon Bile acid emulsions
CN1529603A (zh) * 2001-04-17 2004-09-15 �Ƕ�÷�¹������޹�˾ 胆酸或胆盐脂肪酸共轭物的用途
US20060127468A1 (en) * 2004-05-19 2006-06-15 Kolodney Michael S Methods and related compositions for reduction of fat and skin tightening
ES2296463A1 (es) * 2005-07-13 2008-04-16 Universidade De Santiago Compostela Nuevos amidoderivados de acidos billares funcionalizados en la posicion 3 del anillo a. procedimientos para su obtencion y aplicaciones.
WO2010086864A1 (en) * 2009-02-02 2010-08-05 Galmed International Ltd. Methods and compositions for treating alzheimer's disease
US20110256247A1 (en) * 2008-12-31 2011-10-20 Nitromega Corp. Topical compositions containing nitro fatty acids

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6019992A (en) * 1998-12-04 2000-02-01 Chesebrough-Pond's Usa Co. Cosmetic skin care compositions containing 4-chromanone
US8975246B2 (en) * 2001-04-17 2015-03-10 Galmed Research And Development Ltd. Bile acid or bile salt fatty acid conjugates
GB0722077D0 (en) * 2007-11-09 2007-12-19 Smithkline Beecham Corp Compounds
KR20100138918A (ko) * 2008-03-11 2010-12-31 가부시키가이샤 시세이도 피부 미백 방법, 및, 피부 검버섯 형성 억제 및/또는 제거 인자의 스크리닝 방법
AU2014304079A1 (en) * 2013-08-08 2016-02-25 Galmed Research & Development Ltd. Anti-acne compositions comprising bile acid-fatty acid conjugates
ES2732845T3 (es) * 2013-12-04 2019-11-26 Galmed Res & Development Ltd Sales de Aramchol

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4115313A (en) * 1974-10-08 1978-09-19 Irving Lyon Bile acid emulsions
CN1529603A (zh) * 2001-04-17 2004-09-15 �Ƕ�÷�¹������޹�˾ 胆酸或胆盐脂肪酸共轭物的用途
US20060127468A1 (en) * 2004-05-19 2006-06-15 Kolodney Michael S Methods and related compositions for reduction of fat and skin tightening
ES2296463A1 (es) * 2005-07-13 2008-04-16 Universidade De Santiago Compostela Nuevos amidoderivados de acidos billares funcionalizados en la posicion 3 del anillo a. procedimientos para su obtencion y aplicaciones.
US20110256247A1 (en) * 2008-12-31 2011-10-20 Nitromega Corp. Topical compositions containing nitro fatty acids
WO2010086864A1 (en) * 2009-02-02 2010-08-05 Galmed International Ltd. Methods and compositions for treating alzheimer's disease

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109503693A (zh) * 2018-12-12 2019-03-22 合肥工业大学 一种利用胆酸和花生酸为原料高效合成Aramchol的新工艺
WO2024012317A1 (zh) * 2022-07-14 2024-01-18 爱医谷(苏州)生物科技有限公司 一种用于抵抗衰老的组合物及其用途或方法
CN116236490A (zh) * 2023-02-14 2023-06-09 四川大学 脱氧胆酸的用途及药物

Also Published As

Publication number Publication date
AU2014304078A1 (en) 2016-02-25
US20160175223A1 (en) 2016-06-23
HK1224198A1 (zh) 2017-08-18
CA2920456A1 (en) 2015-02-12
EP3030221A4 (en) 2017-02-08
IL227890A0 (en) 2014-01-30
JP2016527306A (ja) 2016-09-08
EP3030221A1 (en) 2016-06-15
WO2015019358A1 (en) 2015-02-12
IL243964A0 (en) 2016-04-21

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