JP2016527306A - 胆汁酸−脂肪酸抱合体を含む抗老化組成物 - Google Patents

胆汁酸−脂肪酸抱合体を含む抗老化組成物 Download PDF

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JP2016527306A
JP2016527306A JP2016532791A JP2016532791A JP2016527306A JP 2016527306 A JP2016527306 A JP 2016527306A JP 2016532791 A JP2016532791 A JP 2016532791A JP 2016532791 A JP2016532791 A JP 2016532791A JP 2016527306 A JP2016527306 A JP 2016527306A
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acid
skin
composition
fabac
present
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Japanese (ja)
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JP2016527306A5 (enExample
Inventor
ダヤン，ナバ
バハラフ，アレン
Original Assignee
ガルデルム セラピューティクス リミテッド
ガルデルム セラピューティクス リミテッド
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Publication of JP2016527306A publication Critical patent/JP2016527306A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63—Steroids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A61K2800/522—Antioxidants; Radical scavengers

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
JP2016532791A 2013-08-08 2014-08-07 胆汁酸−脂肪酸抱合体を含む抗老化組成物 Pending JP2016527306A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IL227890A IL227890A0 (en) 2013-08-08 2013-08-08 Antiaging compounds containing bile acid and fatty acid conjugates
IL227890 2013-08-08
PCT/IL2014/050717 WO2015019358A1 (en) 2013-08-08 2014-08-07 Anti-aging compositions comprising bile acid-fatty acid conjugates

Publications (2)

Publication Number Publication Date
JP2016527306A true JP2016527306A (ja) 2016-09-08
JP2016527306A5 JP2016527306A5 (enExample) 2017-09-14

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JP2016532791A Pending JP2016527306A (ja) 2013-08-08 2014-08-07 胆汁酸−脂肪酸抱合体を含む抗老化組成物

Country Status (9)

Country Link
US (1) US20160175223A1 (enExample)
EP (1) EP3030221A4 (enExample)
JP (1) JP2016527306A (enExample)
CN (1) CN105611910A (enExample)
AU (1) AU2014304078A1 (enExample)
CA (1) CA2920456A1 (enExample)
HK (1) HK1224198A1 (enExample)
IL (2) IL227890A0 (enExample)
WO (1) WO2015019358A1 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024525832A (ja) * 2021-07-16 2024-07-12 スカイ・セラピューティクス・カンパニー・リミテッド 胆汁酸又は胆汁酸塩の分子会合体を含む化粧料組成物
JP2025122058A (ja) * 2019-10-31 2025-08-20 共栄化学工業株式会社 皮膚外用剤
JP7788774B2 (ja) 2019-10-31 2025-12-19 共栄化学工業株式会社 皮膚外用剤

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2920457A1 (en) * 2013-08-08 2015-02-12 Galderm Therapeutics Ltd. Anti-acne compositions comprising bile acid-fatty acid conjugates
WO2016199137A1 (en) 2015-06-10 2016-12-15 Galmed Research And Development Ltd. Low dose compositions of aramchol salts
US11571431B2 (en) 2013-12-04 2023-02-07 Galmed Research And Development Ltd Aramchol salts
US20180000793A1 (en) 2015-02-06 2018-01-04 Ernesto Abel-Santos Inhibiting Germination of Clostridium Perfringens Spores to Reduce Necrotic Enteritis
IL243707A0 (en) 2016-01-20 2016-05-01 Galmed Res And Dev Ltd Treatment to regulate the microbiota in the intestine
US11197870B2 (en) 2016-11-10 2021-12-14 Galmed Research And Development Ltd Treatment for hepatic fibrosis
CN109503693B (zh) * 2018-12-12 2021-04-06 合肥工业大学 一种利用胆酸为原料合成Aramchol的工艺
EP4398890A4 (en) * 2021-09-09 2025-07-30 The Board Of Regents Of The Nevada System Of Higher Education On Behalf Of The Univ Of Nevada Las Ve C. Difficile Spore Germination Inhibitors
WO2024012317A1 (zh) * 2022-07-14 2024-01-18 爱医谷(苏州)生物科技有限公司 一种用于抵抗衰老的组合物及其用途或方法
CN116236490A (zh) * 2023-02-14 2023-06-09 四川大学 脱氧胆酸的用途及药物

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002531483A (ja) * 1998-12-04 2002-09-24 ユニリーバー・ナームローゼ・ベンノートシヤープ ４−クロマノンを含有する皮膚手入れ用化粧品組成物
ES2296463A1 (es) * 2005-07-13 2008-04-16 Universidade De Santiago Compostela Nuevos amidoderivados de acidos billares funcionalizados en la posicion 3 del anillo a. procedimientos para su obtencion y aplicaciones.
WO2009113446A1 (ja) * 2008-03-11 2009-09-17 株式会社資生堂 皮膚美白方法、並びに、皮膚シミ形成抑制及び／又は除去因子のスクリーニング方法
JP2011503031A (ja) * 2007-11-09 2011-01-27 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー ステアロイル−ＣｏＡデサチュラーゼ阻害薬として用いるための１，２，３−トリアゾール誘導体

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4115313A (en) * 1974-10-08 1978-09-19 Irving Lyon Bile acid emulsions
IL142650A (en) * 1998-04-08 2007-06-03 Galmed Int Ltd Use of bile acid conjugates or bile salts and fatty acids or fatty acids in the preparation of pharmaceuticals for lowering cholesterol, for the treatment of fatty liver and for the treatment of hyperglycemia and diabetes
US8975246B2 (en) * 2001-04-17 2015-03-10 Galmed Research And Development Ltd. Bile acid or bile salt fatty acid conjugates
US20060127468A1 (en) * 2004-05-19 2006-06-15 Kolodney Michael S Methods and related compositions for reduction of fat and skin tightening
US8937194B2 (en) * 2008-12-31 2015-01-20 Nitromega Corp. Topical compositions containing nitro fatty acids
WO2010086864A1 (en) * 2009-02-02 2010-08-05 Galmed International Ltd. Methods and compositions for treating alzheimer's disease
CA2920457A1 (en) * 2013-08-08 2015-02-12 Galderm Therapeutics Ltd. Anti-acne compositions comprising bile acid-fatty acid conjugates
HUE045209T2 (hu) * 2013-12-04 2019-12-30 Galmed Res & Development Ltd Aramchol-sók

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002531483A (ja) * 1998-12-04 2002-09-24 ユニリーバー・ナームローゼ・ベンノートシヤープ ４−クロマノンを含有する皮膚手入れ用化粧品組成物
ES2296463A1 (es) * 2005-07-13 2008-04-16 Universidade De Santiago Compostela Nuevos amidoderivados de acidos billares funcionalizados en la posicion 3 del anillo a. procedimientos para su obtencion y aplicaciones.
JP2011503031A (ja) * 2007-11-09 2011-01-27 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー ステアロイル−ＣｏＡデサチュラーゼ阻害薬として用いるための１，２，３−トリアゾール誘導体
WO2009113446A1 (ja) * 2008-03-11 2009-09-17 株式会社資生堂 皮膚美白方法、並びに、皮膚シミ形成抑制及び／又は除去因子のスクリーニング方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ＡＲＣＨＩＶＥＳ ＯＦ ＭＥＤＩＣＡＬ ＲＥＳＥＡＲＣＨ, vol. Vol.41, Issue 6, JPN6018015557, 2010, pages 397 - 404, ISSN: 0003981950 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2025122058A (ja) * 2019-10-31 2025-08-20 共栄化学工業株式会社 皮膚外用剤
JP7788774B2 (ja) 2019-10-31 2025-12-19 共栄化学工業株式会社 皮膚外用剤
JP2024525832A (ja) * 2021-07-16 2024-07-12 スカイ・セラピューティクス・カンパニー・リミテッド 胆汁酸又は胆汁酸塩の分子会合体を含む化粧料組成物

Also Published As

Publication number Publication date
AU2014304078A1 (en) 2016-02-25
EP3030221A4 (en) 2017-02-08
CA2920456A1 (en) 2015-02-12
WO2015019358A1 (en) 2015-02-12
US20160175223A1 (en) 2016-06-23
IL227890A0 (en) 2014-01-30
EP3030221A1 (en) 2016-06-15
HK1224198A1 (zh) 2017-08-18
CN105611910A (zh) 2016-05-25
IL243964A0 (en) 2016-04-21

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