CN105596598A - Oral traditional Chinese medicine preparation for later stage of bone fracture - Google Patents

Oral traditional Chinese medicine preparation for later stage of bone fracture Download PDF

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CN105596598A
CN105596598A CN201610045955.8A CN201610045955A CN105596598A CN 105596598 A CN105596598 A CN 105596598A CN 201610045955 A CN201610045955 A CN 201610045955A CN 105596598 A CN105596598 A CN 105596598A
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chinese medicine
medicine preparation
bone fracture
prepared
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刘建
孙磊
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
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Abstract

The invention relates to a traditional Chinese medicine preparation, in particular to an oral traditional Chinese medicine preparation for the later stage of a bone fracture. The traditional Chinese medicine preparation is characterized by being prepared from, by weight, 20-30 parts of radix rehmanniae preparata, 20-30 parts of common macrocarpium fruit, 15-20 parts of herba cynomorii, 10-15 parts of fructus lycii, 10-15 parts of semen cuscutae, 10-15 parts of malaytea scurfpea fruit, 10-15 parts of eucommia bark, 15-20 parts of ginseng, 10-15 parts of milkvetch roots, 15-20 parts of rhizoma alismatis, 15-20 parts of radix saposhnikoviae, 10-15 parts of radix angelicae sinensis, 5-10 parts of radix paeoniae alba and 5-10 parts of fructus chaenomelis. The oral traditional Chinese medicine preparation for the later stage of the bone fracture has the advantages that the applied traditional Chinese medicines accord with the Provisions of the Pharmacopoeia of the People's Republic of China, and the medicines are safe and reliable. The medicines are combined, have the effects of strengthening the sinews, benefiting marrow, soothing joints and the like, and have the advantages of being exact in curative effect, quick in effect, high in cure rate, free of side effect and the like for later stage recovery of the bone fracture.

Description

A kind of for the anaphase of bone fracture innerwear Chinese medicine preparation
Technical field
The present invention relates to a kind of Chinese medicine preparation, be specifically related to a kind of for the anaphase of bone fracture innerwear Chinese medicine preparation.
Background technology
When the integrality of bone or cartilage or continuity are interrupted, claim fracture. Comprise obvious cortex bone fracture, also comprise bone trabecularInterrupt i.e. micro-fracture. Wound is fractured normal sclerotin, claims TF, comprises that children's traumatic epiphysis separates.Fracture occurs in osseous lesion position (as tumour, inflammation, metabolic disease etc.) and claims pathologic fracture. Fracture is general all with soft groupThe damage of knitting.
The traditional Chinese medical science is thought, the entirety that people is made up of jointly internal organs, channels and collaterals, skin and flesh, muscles and bones, qi and blood and body fluid etc., human bodyVital movement is the reflection of function, and the material base of dirty functional activity is qi-blood-body fluid. Therefore the generation of traumatology disease andDevelopment has substantial connection with qi and blood muscles and bones, internal organs channels and collaterals etc. Between part and entirety, interact. Think wound illness many byCause that in skin and flesh injured bones and muscles qi and blood stagnation, channels and collaterals block or Tianjin anemia is damaged or the evil poison of hemostasis is fromed superficies to interior, and cause internal organsDiscord, also can, because the internal organs going from the interior to the exterior of getting along well causes channels and collaterals, qi and blood, body fluid pathology, cause skin and flesh muscles and bones disease damage. The injury of the bone is notBe simple damage, damage the injury of the tissues of bone energy, bone is also damaged in the injury of the tissues, and often involves qi and blood and hinder in interior, makes train of thought impaired, stagnation of QI and blood,For " swelling " is " bitterly ". After all wounds, there is swelling, pain, movable function obstacle, and can have deformity because of the change of fracture site position,The malposition of bone is normal, can make the muscle that adheres to nervous and occur resiliently mounted situation.
Chinese traditional treatment fracture, still taking diagnosis and treatment as basis, is implemented " be association of activity and inertia, muscles and bones is laid equal stress on, internal and external application, cooperation between the doctors and patients "Principle of reatment, emphasize organic conception, internal and external application. Handle the reset in fractures, the activity of fixing, do exercises well dialecticallyRelation with medicine treatment. Accomplish that as far as possible the reduction of the fracture does not increase local soft tissue damage, fixing fracture and do not hinder limbs to liveMoving, thereby can promote whole body qi-blood circulating, enhancing metabolism, union and functional rehabilitation are advanced side by side. In the time for the treatment of,Externally applied drug and medicine for oral administration share treatment, no matter be that externally applied drug or medicine for oral administration all will be according to the medications of fractures process specific aim, outstandingIt is medicine for oral administration, in early days should be with promoting blood circulation and removing blood stasis in fracture, and sharp gas pain relieving is main, and mid-term should be in order to blood nourishing acupuncture-stimulating, and strong muscle is strongBone medicine, to promote union, the later stage should be to strengthen muscle benefit marrow, to dredge sharp joint as main. But, fracture in treatment at presentIn medicine for oral administration, often lack the specific aim medication to fracture different times, when treatment simple only with promoting blood circulation and removing blood stasis, strengthen muscles and bonesBe main, often cause the anaphase of bone fracture to recover progress slow, affect Rehabilitation.
Summary of the invention
According to above the deficiencies in the prior art, the invention provides a kind ofly for the anaphase of bone fracture innerwear Chinese medicine preparation, it is evident in efficacy,Safe and reliable, have no side effect, there is wide potential applicability in clinical practice.
One of the present invention, for the anaphase of bone fracture innerwear Chinese medicine preparation, is characterized in that according to parts by weight meter, by with lowerMedicine raw material is prepared from: 20~30 parts of prepared rhizomes of rehmannia, 20~30 parts of dogwood fruits, 15~20 parts of cynomorium songaricums, 10~15 parts of the fruits of Chinese wolfberry, Tu10~15 parts of silk, 10~15 parts of Psoralea corylifolias, 10~15 parts of charred CORTEX EUCOMMIAEs, 15~20 parts of ginsengs, 10~15 parts of the Radixs Astragali, rhizoma alismatis 15~20Part, windproof 15~20 parts, 10~15 parts of Radix Angelicae Sinensis, 5~10 parts of the root of herbaceous peonys, 5~10 parts of pawpaws.
Wherein, preferred version is as follows:
Can, according to parts by weight meter, be prepared from by following Chinese medicine material: 20 parts of prepared rhizomes of rehmannia, 20 parts of dogwood fruits, cynomorium songaricum 15Part, 10 parts of the fruits of Chinese wolfberry, 10 parts of the seed of Chinese dodders, 10 parts of Psoralea corylifolias, 10 parts of charred CORTEX EUCOMMIAEs, 15 parts of ginsengs, 10 parts of the Radixs Astragali, poolRush down 15 parts, windproof 15 parts, 10 parts of Radix Angelicae Sinensis, 5 parts of the root of herbaceous peonys, 5 parts of pawpaws.
Also can, according to parts by weight meter, be prepared from by following Chinese medicine material: 30 parts of prepared rhizomes of rehmannia, 30 parts of dogwood fruits, cynomorium songaricum20 parts, 15 parts of the fruits of Chinese wolfberry, 15 parts of the seed of Chinese dodders, 15 parts of Psoralea corylifolias, 15 parts of charred CORTEX EUCOMMIAEs, 20 parts of ginsengs, 15 parts of the Radixs Astragali,20 parts of rhizoma alismatis, windproof 20 parts, 15 parts of Radix Angelicae Sinensis, 10 parts of the root of herbaceous peonys, 10 parts of pawpaws.
Also can, according to parts by weight meter, be prepared from by following Chinese medicine material: 25 parts of prepared rhizomes of rehmannia, 25 parts of dogwood fruits, cynomorium songaricum18 parts, 12 parts of the fruits of Chinese wolfberry, 12 parts of the seed of Chinese dodders, 12 parts of Psoralea corylifolias, 12 parts of charred CORTEX EUCOMMIAEs, 18 parts of ginsengs, 12 parts of the Radixs Astragali,18 parts of rhizoma alismatis, windproof 18 parts, 12 parts of Radix Angelicae Sinensis, 8 parts of the root of herbaceous peonys, 8 parts of pawpaws.
A kind of preparation method for the anaphase of bone fracture innerwear Chinese medicine preparation of the present invention, in accordance with the following methods preparation: according to joiningSide takes Chinese medicine material and joins in container, and add water to cover powder and soak 10~20 minutes, then add water and do not have 3~5 centimetres of powder,Decoct with high heat to boiling and use again slow fire boiling instead 20~30 minutes, get filtrate; And then add water and do not have 3~5 centimetres of powder, useIntense fire decocts to boiling and uses slow fire boiling instead 15~20 minutes again, then removes slag and gets filtrate, and twice filtrate merges.
While taking, each 300ml, one day twice.
Pharmacology analysis:
Prepared rhizome of rehmannia: taste is sweet, warm in nature. Return liver, kidney channel. Enrich blood moist, beneficial essence is filled out marrow. Sallow for the deficiency of blood, dizzy palpitaition,Irregular menstruation, collapses incessantly, liver-kidney Yin deficiency, hectic fever night sweat, seminal emission impotence, infertility, irregular menstruation, metrostaxis, waistKnees soreness, Hiccough and deaf, the head is dim-sighted, and poliosis is quenched one's thirst, constipation, the syndrome characterized by dyspnea of suffering from a deficiency of the kidney.
Dogwood fruit: sour, puckery, tepor. Return liver, kidney channel. Tonify the liver and kidney, puckery essence is admittedly de-. For dizzy tinnitus, soreness of waist and knee joint,Impotence and seminal emission, enuresis frequent micturition, under uterine bleeding band, profuse sweating collapse. Interior heat is quenched one's thirst.
Cynomorium songaricum: sweet, temperature. Return spleen, kidney, large intestine channel. Kidney-replenishing, benefiting essence-blood, relaxes bowel. Soft for waist knee impotence, impotenceInvoluntary emission, the dry constipation of intestines.
The fruit of Chinese wolfberry: sweet, flat. Return liver, kidney channel. Nourishing liver and kidney, benefiting shrewd head. Lose for consumptive disease essence, soreness of waist and knee joint, dizzyTinnitus, interior heat is quenched one's thirst, and the deficiency of blood is sallow, and blurred vision is not clear.
The seed of Chinese dodder: warm in nature, taste is sweet. Enter liver, kidney channel. Nourishing liver and kidney, controlling nocturnal emission with astringent drugs contracting urine, antiabortive, improving eyesight, antidiarrheal. For sunImpotence seminal emission, dripping urination, enuresis frequent micturition, soreness and weakness of waist and knees, blurred vision tinnitus, vaginal bleeding due to deficiency of the kidney during pregnancy, fetal irritability, spleen are suffered from a deficiency of the kidney and are rushed down.
Psoralea corylifolia: pungent, bitter, temperature. Return kidney, the spleen channel. Warming kidney and enhancing yang, receives gas, antidiarrheal. For impotence and seminal emission, enuresis frequent micturition,Waist knee crymodynia, suffers from a deficiency of the kidney and breathes heavily, Diarrhoea; External application curing vitiligo, alopecia areata.
Charred CORTEX EUCOMMIAE: Gan Weixin, temperature. Enter liver, kidney channel. Filling liver kidney, strengthening the bones and muscles, antiabortive. Control spinal column ache, a little less than limbs impotence,Seminal emission, involuntary emission, Diarrhoea, consumptive disease, dribbling urination, uncontrolled urination is itched, fetal irritability, threatened abortion is wanted to fall, and hydramnios is slidingTire, hypertension.
Ginseng: sweet, micro-hardship, flat. Return spleen, lung, the heart channel of Hang-Shaoyin. Reinforce vital energy, multiple arteries and veins is admittedly de-, reinforces the spleen to benefit the lung, and promotes the production of body fluid, and calms the nerves.De-for the empty wish of body, the cold weak pulse of limb, insufficiency of the spleen food is few, and the deficiency syndrome of the lung is breathed with cough, and Tianjin wound is thirsty, and interior heat is quenched one's thirst, and prolonged illness void is thin, and palpitation with fear is lostSleep, impotence palace is cold; Heart failure, cardiogenic shock.
The Radix Astragali: sweet, temperature. Return lung, the spleen channel. Invigorating qi for strengthening superficies, diuresis holder poison, apocenosis, expelling pus and promoting granulation. It is weak for the deficiency of vital energy,Anorexia and loose stool, the sinking of qi of middle-jiao, rushes down prolapse of the anus for a long time, the uterine bleeding of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy oedema, ulcer is difficult bursts, and burst and do not hold back for a long time,Flaccidity of limbs due to deficiency of blood Huang, interior heat is quenched one's thirst; Chronic nephritis albuminuria, diabetes.
Rhizoma alismatis: sweet, cold. Return kidney, urinary bladder channel. Diuresis, clearing away damp-heat. For difficult urination, oedema turgor, the oliguria of having loose bowels,Phlegmatic vertigo, heat is drenched puckery pain; High fat of blood.
Windproof: acrid, sweet, warm. Return bladder, liver, the spleen channel. Inducing diaphoresis to dispel wind, victory is wet, only convulsion. For cold headache, rheumatismNumbness pain, rubella itch, lockjaw.
Radix Angelicae Sinensis: sweet, acrid, warm. Return liver, the heart, the spleen channel. Enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, relaxes bowel. It is sallow for the deficiency of blood,Dizzy palpitaition, irregular menstruation, through closing dysmenorrhoea, asthenia cold abdominalgia, the dry constipation of intestines, arthralgia due to wind-dampness, injury from falling down, ulcer sores.
The root of herbaceous peony: bitter, sour, be slightly cold. Return liver, the spleen channel. Flat liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating. Be used for having a headache dizzy,Hypochondriac pain, stomachache, four limbs contraction pain, the deficiency of blood is sallow, irregular menstruation, spontaneous perspiration, night sweat.
Pawpaw: acid, temperature. Return liver, the spleen channel. Flat liver relaxing muscles and tendons, and stomach dampness elimination. For arthritis with fixed pain caused by dampness contraction, the heavy pain of waist knee joint acid,Vomit and diarrhoea and have a cramp, beriberi oedema.
In medicament composing prescription of the present invention, prepared rhizome of rehmannia, dogwood fruit, cynomorium songaricum, the fruit of Chinese wolfberry, the seed of Chinese dodder, Psoralea corylifolia, charred CORTEX EUCOMMIAE nourish liverSpleen kidney, life essence-filling, marrow-benefitting; Ginseng, Radix Astragali tonifying vital QI, invigorating qi for strengthening superficies; Rhizoma alismatis, windproof, Radix Angelicae Sinensis, the root of herbaceous peony, pawpaw are dredged Li GuanJoint, dampness removing are let out turbid, evil with antimagnetic greasy love.
The invention has the advantages that used Chinese medicine meets Pharmacopoeia of People's Republic of China regulation, safety of medicine is reliable. All medicine phasesWith there is strong muscle benefit marrow, dredge the effects such as sharp joint, for the anaphase of bone fracture recover to there is determined curative effect, instant effect, cure rate are high,The feature such as have no side effect.
Curative effect judgement:
1, inclusion criteria
Choose fracture patient 100 example and all in the anaphase of bone fracture, wherein, the male sex's 70 examples, women's 30 examples, are divided into experimentGroup 50 example and control group 50 examples.
2, methods for the treatment of
Experimental group is taken Chinese medicine preparation of the present invention, oral, every day 2 times, each 1 time sooner or later, each 300ml. Control group is takenThe strong osteocomma treatment of compound.
3, result
After 15 days, experimental group recovery from illness patient is 47 examples, accounts for 94%, and contrast groups recovery from illness patient is 36 examples, accounts for 72%, therefore,Experimental group is obviously better than contrast groups.
Below enumerate a model case:
(1) Wei, man, 25 years old, when sports, accidentally to fall down, right chest pain, deeply breathes, coughs, gets up, crouchesSevere pain when bed, through X-ray examination, patient left side chest 3,4 fractures of rib, the later stage adopts Chinese medicine preparation of the present invention to control while recoveryTreat, can be freely movable after every 10 days, recovery from illness.
Detailed description of the invention
The present invention will be further described by the following examples.
Embodiment 1:
A kind of for the anaphase of bone fracture innerwear Chinese medicine preparation, according to parts by weight meter, be prepared from by following Chinese medicine material: prepared rhizome of rehmannia20 parts, 20 parts of dogwood fruits, 15 parts of cynomorium songaricums, 10 parts of the fruits of Chinese wolfberry, 10 parts of the seed of Chinese dodders, 10 parts of Psoralea corylifolias, 10 parts of charred CORTEX EUCOMMIAEs,15 parts of ginsengs, 10 parts of the Radixs Astragali, 15 parts of rhizoma alismatis, windproof 15 parts, 10 parts of Radix Angelicae Sinensis, 5 parts of the root of herbaceous peonys, 5 parts of pawpaws.
Embodiment 2:
A kind of for the anaphase of bone fracture innerwear Chinese medicine preparation, according to parts by weight meter, be prepared from by following Chinese medicine material: prepared rhizome of rehmannia30 parts, 30 parts of dogwood fruits, 20 parts of cynomorium songaricums, 15 parts of the fruits of Chinese wolfberry, 15 parts of the seed of Chinese dodders, 15 parts of Psoralea corylifolias, 15 parts of charred CORTEX EUCOMMIAEs,20 parts of ginsengs, 15 parts of the Radixs Astragali, 20 parts of rhizoma alismatis, windproof 20 parts, 15 parts of Radix Angelicae Sinensis, 10 parts of the root of herbaceous peonys, 10 parts of pawpaws.
Embodiment 3:
A kind of for the anaphase of bone fracture innerwear Chinese medicine preparation, according to parts by weight meter, be prepared from by following Chinese medicine material: prepared rhizome of rehmannia25 parts, 25 parts of dogwood fruits, 18 parts of cynomorium songaricums, 12 parts of the fruits of Chinese wolfberry, 12 parts of the seed of Chinese dodders, 12 parts of Psoralea corylifolias, 12 parts of charred CORTEX EUCOMMIAEs,18 parts of ginsengs, 12 parts of the Radixs Astragali, 18 parts of rhizoma alismatis, windproof 18 parts, 12 parts of Radix Angelicae Sinensis, 8 parts of the root of herbaceous peonys, 8 parts of pawpaws.
Embodiment 4:
Embodiment 1~3 is prepared in accordance with the following methods: take Chinese medicine material and join in container according to formula, adding water and cover powderSoak 20 minutes, then add water and do not have 5 centimetres of powder, decoct with high heat to boiling and use again slow fire boiling instead 30 minutes, get filtrate;And then add water and do not have 5 centimetres of powder, decoct with high heat to boiling and use again slow fire boiling instead 20 minutes, then remove slag and get filtrate,Twice filtrate merges.
While taking, each 300ml, one day twice.

Claims (4)

1. for a anaphase of bone fracture innerwear Chinese medicine preparation, it is characterized in that, according to parts by weight meter, being prepared by following Chinese medicine materialForm: 20~30 parts of prepared rhizomes of rehmannia, 20~30 parts of dogwood fruits, 15~20 parts of cynomorium songaricums, 10~15 parts of the fruits of Chinese wolfberry, the seed of Chinese dodder 10~15Part, 10~15 parts of Psoralea corylifolias, 10~15 parts of charred CORTEX EUCOMMIAEs, 15~20 parts of ginsengs, 10~15 parts of the Radixs Astragali, 15~20 parts of rhizoma alismatis, anti-15~20 parts of wind, 10~15 parts of Radix Angelicae Sinensis, 5~10 parts of the root of herbaceous peonys, 5~10 parts of pawpaws.
2. one according to claim 1, for the anaphase of bone fracture innerwear Chinese medicine preparation, is characterized in that according to parts by weight meter,Be prepared from by following Chinese medicine material: 20 parts of prepared rhizomes of rehmannia, 20 parts of dogwood fruits, 15 parts of cynomorium songaricums, 10 parts of the fruits of Chinese wolfberry, the seed of Chinese dodder10 parts, 10 parts of Psoralea corylifolias, 10 parts of charred CORTEX EUCOMMIAEs, 15 parts of ginsengs, 10 parts of the Radixs Astragali, 15 parts of rhizoma alismatis, windproof 15 parts, Radix Angelicae Sinensis10 parts, 5 parts of the root of herbaceous peonys, 5 parts of pawpaws.
3. one according to claim 1, for the anaphase of bone fracture innerwear Chinese medicine preparation, is characterized in that according to parts by weight meter,Be prepared from by following Chinese medicine material: 30 parts of prepared rhizomes of rehmannia, 30 parts of dogwood fruits, 20 parts of cynomorium songaricums, 15 parts of the fruits of Chinese wolfberry, the seed of Chinese dodder15 parts, 15 parts of Psoralea corylifolias, 15 parts of charred CORTEX EUCOMMIAEs, 20 parts of ginsengs, 15 parts of the Radixs Astragali, 20 parts of rhizoma alismatis, windproof 20 parts, Radix Angelicae Sinensis15 parts, 10 parts of the root of herbaceous peonys, 10 parts of pawpaws.
4. one according to claim 1, for the anaphase of bone fracture innerwear Chinese medicine preparation, is characterized in that according to parts by weight meter,Be prepared from by following Chinese medicine material: 25 parts of prepared rhizomes of rehmannia, 25 parts of dogwood fruits, 18 parts of cynomorium songaricums, 12 parts of the fruits of Chinese wolfberry, the seed of Chinese dodder12 parts, 12 parts of Psoralea corylifolias, 12 parts of charred CORTEX EUCOMMIAEs, 18 parts of ginsengs, 12 parts of the Radixs Astragali, 18 parts of rhizoma alismatis, windproof 18 parts, Radix Angelicae Sinensis12 parts, 8 parts of the root of herbaceous peonys, 8 parts of pawpaws.
CN201610045955.8A 2016-01-16 2016-01-16 Oral traditional Chinese medicine preparation for later stage of bone fracture Withdrawn CN105596598A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105816593A (en) * 2016-06-01 2016-08-03 朱朝晖 Orally-taken traditional Chinese medicine preparation for later-stage treatment and rehabilitation of fracture
CN112957421A (en) * 2021-04-12 2021-06-15 平山县碾沟道慈药房有限公司 Compound pill for reinforcing middle-jiao and strengthening walking and preparation method thereof

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102078482A (en) * 2011-01-10 2011-06-01 刘兰梅 Traditional Chinese medicine combination for treating bone injury and fracture and preparation method of the same
CN104547862A (en) * 2014-12-31 2015-04-29 东莞市智健医疗科技有限公司 Use of traditional Chinese medicine preparation in preparation of medicine for treating bone fracture
CN104984175A (en) * 2015-08-03 2015-10-21 张德东 Composition for treating bone fracture later-period osteoporosis and bone nonunion

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102078482A (en) * 2011-01-10 2011-06-01 刘兰梅 Traditional Chinese medicine combination for treating bone injury and fracture and preparation method of the same
CN104547862A (en) * 2014-12-31 2015-04-29 东莞市智健医疗科技有限公司 Use of traditional Chinese medicine preparation in preparation of medicine for treating bone fracture
CN104984175A (en) * 2015-08-03 2015-10-21 张德东 Composition for treating bone fracture later-period osteoporosis and bone nonunion

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105816593A (en) * 2016-06-01 2016-08-03 朱朝晖 Orally-taken traditional Chinese medicine preparation for later-stage treatment and rehabilitation of fracture
CN112957421A (en) * 2021-04-12 2021-06-15 平山县碾沟道慈药房有限公司 Compound pill for reinforcing middle-jiao and strengthening walking and preparation method thereof

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