CN105596576A - Tea bag with blood fat reducing action - Google Patents
Tea bag with blood fat reducing action Download PDFInfo
- Publication number
- CN105596576A CN105596576A CN201511010975.3A CN201511010975A CN105596576A CN 105596576 A CN105596576 A CN 105596576A CN 201511010975 A CN201511010975 A CN 201511010975A CN 105596576 A CN105596576 A CN 105596576A
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- CN
- China
- Prior art keywords
- leaves
- blood fat
- tea
- ampelopsis grossedentata
- nerved spicebush
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/82—Theaceae (Tea family), e.g. camellia
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23F—COFFEE; TEA; THEIR SUBSTITUTES; MANUFACTURE, PREPARATION, OR INFUSION THEREOF
- A23F3/00—Tea; Tea substitutes; Preparations thereof
- A23F3/06—Treating tea before extraction; Preparations produced thereby
- A23F3/14—Tea preparations, e.g. using additives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
Abstract
A tea bag with a blood fat reducing action is formed by mixing, smashing and packaging green tea, ampelopsis grossedentata leaves, golden camellia and three-nerved spicebush leaves. The ampelopsis grossedentata leaves, golden camellia and three-nerved spicebush leaves can reduce TC, TG, and LDL-C levels of serum and increase HDL-C level of the serum, the ampelopsis grossedentata leaves can also improve serum SOD activity, reduce a liver coefficient and relieve a damage action of high fat to liver cells. The three-nerved spicebush leaves can reduce an arteriosclerosis index AI, a fat coefficient and body weight and relieve fatty degeneration degree of the liver, and lipid droplet formation in the HpeG2 cells is obviously reduced. The ampelopsis grossedentata leaves, golden camellia and three-nerved spicebush leaves coordinately act and are superior to single ampelopsis grossedentata leaf general flavone, single golden camellia total polysaccharide extract and single three-nerved spicebush leaf general flavone in the blood fat reducing effect and has more comprehensive preventing action agaisnt blood fat and blood fat-reducing effect.
Description
Technical field
The present invention relates to a kind of drink with health care, specifically relate to a kind of joining of medicinal herb components of containingSide's tea.
Technical background
Have tea good for health, be more and more subject to popular liking, become gradually a kind of trend. But drink tea merely, health-care efficacyCoverage rate is narrower. From another viewpoint, along with the raising of modern life level, people's food such as high fat, high protein of taking food increases,Cause middle-aged and old hyperlipemias more and more. And high fat of blood very easily causes the generation of various cardiovascular and cerebrovascular diseases, seriousThreatening people's physical and mental health. Existing blood lipid-lowering medicine has side effect mostly, unsuitable long-term drinking. Hyperlipidemia be due toBody lipid metabolism imbalance and obviously abnormal a kind of disease of one or more lipid components in hyperamization is generally acknowledged cardiovascular and cerebrovascularThe Major Risk Factors of disease is also one of Etiological causing fatty liver simultaneously. Ampelopsis grossdentata leaf, Camellia nitidissima, the root of three-nerved spicebushLeaf is not only pure natural plant, and all has good hypolipemic function, and the suitable mode of taking, for brewing, is combined to tea-drinkingIt is more suitable in material, to take with drinking tea, but there is no above-mentioned Chinese medicine material and the mixed composition of taking Instant Drinks of tealeaves in the past.
Summary of the invention
The object of the present invention is to provide a kind of tea in bag with effect for reducing blood fat. In tealeaves, fill into and there is the height of preventingThe Chinese medicine material of blood fat disease, increases the health care of anti-curing hyperlipemia by tea drinking habit.
Tea in bag of the present invention, comprises following raw material: green tea 10-20 weight portion, ampelopsis grossdentata leaf 5-10 weight portion, goldJasmine tea 10-20 weight portion, combined spicebush leaf 5-15 weight portion.
The present invention is based on ampelopsis grossdentata, belongs to Vitaceae, and Ampelopsis, is perennial liana, claims again Mao YanThe certain kind of berries, wild vine tea, vine tea, white tea, white tea cake, be mainly distributed in the height above sea level such as Hunan, Guangdong, Yunnan, Guizhou, Hubei, Jiangxi, FujianThe mountain region of 400 ~ 1300m and limit, ditch. In ampelopsis grossdentata leaf, main active ingredient is flavonoids (being mainly dibydro myricetrin)It has that anti-oxidant, analgesia, cough-relieving, broad-spectrum are antibacterial, liver protecting, hypoglycemic, reducing blood lipid, enhancing body immunity and inhibitionThe multiple efficacies such as tumour, its industrial applications has a extensive future, and can be applied in food, functional food and pharmaceuticals industry. MirrorIn this, the flavonoids developing in ampelopsis grossdentata leaf is of great practical significance. Yang Xin jumps to study and shows, vine teaWith lotus leaf water extract to rat tool functions of lowering blood-fat and reducing weight. The researchs such as Chen Yuqiong, Liu Cuie, Li Yushan show that vine tea water extraction liquid is to heightBlood fat rat has prevention effect. The researchs such as Chen Xiaojun show, ampelopsis grossdentata flavones is to yolk type hyperlipemia in mice serumTC, TG have reducing effect. Dibydro myricetrin has and obviously alleviates effect hyperlipemia in mice body weight; Flavones and dibydro myricetrinMice serum TC, TG, LDL-C, MDA content be can reduce in various degree, Serum HDL-C content and SOD activity improved,Reduce liver coefficient. The of science observation of hepatopathy show, feeds and raise vine tea flavone and the sex change of dibydro myricetrin group mouse liver cell, swellingDegree alleviates. Illustrate that vine tea flavone and dibydro myricetrin can reduce lipid of mice, strengthen antioxidant ability of organism, alleviate high fat of bloodTo hepatocellular damaging action.
Camellia nitidissima is camellia section Camellia Camellia Section Chrysantha, early 1960s in China Guangxi first byFinding, is the rare plant resources in a kind of world. Recent study discovery, golden camellia tea contains tea polysaccharide, Tea Polyphenols, tea soapThe multiple physiologically active ingredient such as glucoside, flavonoids, contains abundant germanium, selenium and zinc etc. simultaneously and maintains the trace unit that health is usefulElement. Animal and clinical trial show that golden camellia tea has inhibitory action to transplantability malignant tumour, also have hypotensive, reducing blood lipid,Reduce the effects such as cholesterol and atherosclerosis, along with deepening continuously that people study Camellia nitidissima, the height of Camellia nitidissimaThe potentiality of active component and the medicinal aspect of medical science are familiar with by common people gradually. High, medium and low 3 dosage of camellia chrysantha polysaccharideGroup all can reduce TC, TG and the LDL-C level in hyperlipemia mice serum extremely significantly, improves HDL-C/TCRatio.
The root of three-nerved spicebush is Lauraceae Lindera plant, is traditional conventional Chinese medicine, is one of important warm stomach medicines for regulating qi and alleviating pain, hasEffect of warming spleen and stomach for dispelling cold, regulating qi-flowing for relieving pain. " Chinese pharmacopoeia " recorded its root, stem, Ye Junke and is used as medicine, and multiplex its root of successive dynasties side's book,The description of its leaf is few. In recent years, to the analysis of combined spicebush leaf, existing institute makes progress, multiple sesquiterpene lactone and flavones ingredient bySeparate. Pharmacology activity research about combined spicebush leaf general flavone is less, and we find combined spicebush leaf general flavone Wheat Protein recently,And the mouse liver injury that carbon tetrachloride is caused shields. Because much research shows the antioxidation of flavones ingredientHave certain associatedly with effect for reducing blood fat, studied at hyperlipidemia fatty liver mouse model and hepatic cell fattydegeneration body for this reasonOn external model, the fat-reducing effect of combined spicebush leaf general flavone and the impact on liver fat sex change thereof are investigated. At induced Hyperlipidemia in MiceIn property fatty liver model, the middle and high dosage of combined spicebush leaf general flavone all can to a certain degree reduce serum TC, TG, LDLC level,Wherein high dose group TC has significant difference compared with model group. Combined spicebush leaf general flavone can also reduce liver in dose dependent groundLipid coefficient, fat coefficient, AI and body weight, and alleviate the steatosis degree of liver. Along with the increasing of combined spicebush leaf general flavone concentrationAdd, in HpeG2 cell, fat drips to form obviously and reduces.
Three is carried out to prescription, Synergistic, definite functions, quality controllable, take safety.
Good effect of the present invention is: ampelopsis grossdentata leaf, Camellia nitidissima, combined spicebush leaf all can reduce serum TC, TG,LDL-C level, the effect of elevating HDL-C level, ampelopsis grossdentata leaf can also improve activity of SOD in serum, reduces liver systemNumber, alleviates high fat to hepatocellular damaging action. Combined spicebush leaf also can reduce atherogenic index AI, can also reduce fatty seriesCount and body weight, alleviate the steatosis degree of liver, in HpeG2 cell, fat drips to form obviously and reduces. Three is worked on the three areas simultaneously, collaborativeEffect, can more comprehensively play the effect of prevention and reducing blood lipid.
Instructions of taking, drinks tea with daily.
Preparation method is: takes raw material by proportioning, gets green tea, ampelopsis grossdentata leaf, Camellia nitidissima, combined spicebush leaf co-grinding,Mix rear mistake 60 mesh sieves, 100 DEG C of sterilizations, with steeping bag packing and get final product.
Drug effect detects
Materials and methods
1 material
(1) the clean level of animal male SD rat, body weight (200 ± 20) g,, is had by Changchun hundred million these animal used as test technology totally by 90Limit responsible company provides, credit number SCXK(Ji)-2011-0004.
(2) warm water's soak extract concentrated extract of the medicine present composition, positive control drug blood fat recovery capsule(hereinafter to be referred as Effects of Xuezhikang, Beijing WBL Peking University Biotech Co., Ltd provides, lot number: 10950029).
High lipid food be 1% cholesterol, 10% lard, 2% yolk powder, 1% pig cholate, 0.2% methylthiouracil,85.8% basal feed, is provided and is processed into by Changchun University of Traditional Chinese Medicine's zoopery center.
(4) instrument GRT-3000 semi-automatic biochemical analyzer (Jinan Ge Lite Science and Technology Ltd.); The desk-top height of TG-20MSpeed centrifuge (Beijing rich space Proview experimental facilities Co., Ltd); HHS11-6-S electric-heated thermostatic water bath (Shanghai Hu Yueming sectionLearn Instrument Ltd.).
(5) reagent HDL-C (HDL-C) (lot number 2400108), LDL-C (LDL-C) (lot number 400109), T-CHOL (TC) (lot number 2400106), the above mensuration of triglycerides (TG) (lot number 2400107) are triedAgent box is produced by Hunan Yonghe-Yangguang Science and Technology Co., Ltd..
Method
(1) animal grouping, with modeling by 90 of rats, is divided into 9 groups at random. Wherein 10 feeding normal diet rats are normalControl group. All the other rat feeding high lipid foods are modeling group. With adopting random digit method to be divided into model by hyperlipidemia ratsControl group, Effects of Xuezhikang control group, the high, medium and low dosage group of golden grape tea in bag (hereinafter to be referred as high, medium and low dosage group).
(2) nursing and medication are except Normal group, and model control group and each administration group are all fed with high lipid food. JustNormal control group and model control group give respectively isometric(al) distilled water; Effects of Xuezhikang control group dosage is pressed 60kg and is become human body surfaceLong-pending conversion, is clinical equivalent dosage, Effects of Xuezhikang control group 1.80g/kg. All the other each group gives that golden grape tea in bag is concentrated to be soakedCream, the high, medium and low dosage group of golden grape tea in bag is respectively 2.43g/kg, 1.62g/kg, 0.81g/kg, every day 1 time, gives continuouslyMedicine 30d. Experimental session animal freely drinks water, and observes its appetite, active situation every day, weekly test body quality 1 time.
(3) biochemical indicator detects and raises continuously after 30 days, fasting (can't help water) 12h, and tail vein blood, surveys blood lipids index,Be HDL-C, LDL-C, T-CHOL, the triglycerides of serum.
Measure rat body weight, serum middle-high density lipoprotein cholesterol, LDL-C, T-CHOL, sweetOil three esters and atherogenic index. Results of Animal is as follows:
The impact of warm water's soak extract of table 1 present composition on hyperlipemia rat body weight (±s，n=10）
Note: with control group than * P < 0.05; With model group than * * P < 0.05; With Effects of Xuezhikang group than △ P > 0.05; High, medium and lowBetween each dosage group, compare P > 0.05.
As shown in Table 1, the present composition can alleviate the body weight of mouse.
The impact of warm water's soak extract of table 2 present composition on TC, TG content in rat blood serum (±s，n=10）
Note: with model group than * P < 0.05; With Effects of Xuezhikang group than △ P > 0.05; With high dose group ratio ▲ P > 0.05; With middle doseAmount group is than ☆ P < 0.05.
As shown in Table 2, warm water's soak extract of the present composition can reduce the content of mouse TC, TG, therebyReduce blood fat.
Warm water's soak extract of table 3 present composition is to HDL-C, LDL-C content and AI in rat blood serumImpact (±s，n=10）
Note: with model group than * P < 0.05; With Effects of Xuezhikang group than △ P > 0.05; With high dose group ratio ▲ P > 0.05; AI isThe ratio of LDL-C content and HDL-C content.
As shown in Table 3, warm water's soak extract of the present composition can reduce the content of mouse LDL-C, raisesThe content of mouse HDL-C, reduces ratio AI, thereby reduces blood fat.
Can find out from the above results, warm water's soak extract of the present composition can alleviate the body of mouseHeavy, reduce TC, TG, LDL-C, rising HDL-C, reduces ratio AI. More comprehensively reduce blood fat, play the work of auxiliary antilipemicWith. Illustrating: warm water's soak extract of the present composition has good auxiliary lipid-lowering function, is that one can be long-termThe health protection tea taking.
The preparation method of the concentrated extract using during above-mentioned drug effect detects is: get green tea, ampelopsis grossdentata leaf, Camellia nitidissima,Combined spicebush leaf co-grinding, mixes rear mistake 60 mesh sieves, and 100 DEG C of sterilizations brew 5min with 150mL boiling water, brew 3 times, by instituteObtain tea and be concentrated into relative density 1.00 left and right, obtain concentrated extract.
Detailed description of the invention
Embodiment mono-: get green tea 10 weight portions, ampelopsis grossdentata leaf 7 weight portions, Camellia nitidissima 15 weight portions, combined spicebush leaf 10 weightsAmount part, co-grinding, crosses 60 mesh sieves, and 100 DEG C of sterilizations, pack and get final product.
Embodiment bis-: get green tea 15 weight portions, ampelopsis grossdentata leaf 10 weight portions, Camellia nitidissima 20 weight portions, combined spicebush leaf 15Weight portion, co-grinding, crosses 60 mesh sieves, and 100 DEG C of sterilizations, pack and get final product.
Embodiment tri-: get green tea 20 weight portions, ampelopsis grossdentata leaf 5 weight portions, Camellia nitidissima 10 weight portions, combined spicebush leaf 5 weightsAmount part, co-grinding, crosses 60 mesh sieves, and 100 DEG C of sterilizations, pack and get final product.
Claims (1)
1. a tea in bag with effect for reducing blood fat, is characterized in that: comprise green tea 10-20 weight portion, ampelopsis grossdentata leaf5-10 weight portion, Camellia nitidissima 10-20 weight portion, combined spicebush leaf 5-15 weight portion, through mixing, pulverizing, packing bubble bag forms.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201511010975.3A CN105596576A (en) | 2015-12-30 | 2015-12-30 | Tea bag with blood fat reducing action |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201511010975.3A CN105596576A (en) | 2015-12-30 | 2015-12-30 | Tea bag with blood fat reducing action |
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| Publication Number | Publication Date |
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| CN105596576A true CN105596576A (en) | 2016-05-25 |
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| CN201511010975.3A Pending CN105596576A (en) | 2015-12-30 | 2015-12-30 | Tea bag with blood fat reducing action |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106511793A (en) * | 2016-10-21 | 2017-03-22 | 浙江工业大学 | Medicinal and dietary composition having effect of decreasing blood fat and application of composition |
| CN106615361A (en) * | 2016-12-02 | 2017-05-10 | 广西中港高科国宝金花茶产业有限公司 | Flavored bag tea of golden camellia and production method of flavored bag tea |
| CN108850302A (en) * | 2018-08-08 | 2018-11-23 | 廖家平 | Health protection tea |
| CN113498819A (en) * | 2021-08-19 | 2021-10-15 | 武汉禾本泰医药科技有限公司 | Lipid-lowering tea |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102499298A (en) * | 2012-01-06 | 2012-06-20 | 雷雨田 | Health care tea and preparation method thereof |
| CN104322745A (en) * | 2014-10-20 | 2015-02-04 | 安徽益方堂生物工程有限公司 | Health-care tea with functions of preventing sunstroke and reducing temperature and preparation method thereof |
| CN105146655A (en) * | 2015-09-07 | 2015-12-16 | 王保红 | Drink composition containing tea flower as well as preparation method and application of drink composition |
-
2015
- 2015-12-30 CN CN201511010975.3A patent/CN105596576A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102499298A (en) * | 2012-01-06 | 2012-06-20 | 雷雨田 | Health care tea and preparation method thereof |
| CN104322745A (en) * | 2014-10-20 | 2015-02-04 | 安徽益方堂生物工程有限公司 | Health-care tea with functions of preventing sunstroke and reducing temperature and preparation method thereof |
| CN105146655A (en) * | 2015-09-07 | 2015-12-16 | 王保红 | Drink composition containing tea flower as well as preparation method and application of drink composition |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106511793A (en) * | 2016-10-21 | 2017-03-22 | 浙江工业大学 | Medicinal and dietary composition having effect of decreasing blood fat and application of composition |
| CN106615361A (en) * | 2016-12-02 | 2017-05-10 | 广西中港高科国宝金花茶产业有限公司 | Flavored bag tea of golden camellia and production method of flavored bag tea |
| CN108850302A (en) * | 2018-08-08 | 2018-11-23 | 廖家平 | Health protection tea |
| CN113498819A (en) * | 2021-08-19 | 2021-10-15 | 武汉禾本泰医药科技有限公司 | Lipid-lowering tea |
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| PB01 | Publication | ||
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Application publication date: 20160525 |