CN105596506A

CN105596506A - Medicament for treating infantile hand-foot-mouth disease

Info

Publication number: CN105596506A
Application number: CN201610010751.0A
Authority: CN
Inventors: 李土才
Original assignee: Foshan Hengnan Medicine Technology Co Ltd
Current assignee: Foshan Hengnan Medicine Technology Co Ltd
Priority date: 2016-01-08
Filing date: 2016-01-08
Publication date: 2016-05-25

Abstract

The invention provides a medicament for treating an infantile hand-foot-mouth disease. The medicament is used for treating the infantile hand-foot-mouth disease through the effects of clearing heat, removing toxicity, expelling dampness and an anti-virus therapy. The medicament is prepared from, by weight, 10-15 parts of honeysuckle flowers, 10-15 parts of radix scutellariae, 10-15 parts of fructus forsythiae, 10-15 parts of cortex phellodendri, 10-15 parts of officinal magnolia bark, 8-12 parts of isatis roots, 8-12 parts of folium isatidis, 5-10 parts of herba periliae, 5-10 parts of wrinkled gianthyssop herb, 3-8 parts of white mulberry root-bark and 3-8 parts of rhizoma coptidis.

Description

A kind of medicament for the treatment of Hand-Food-Mouth Disease

Technical field

The present invention relates to field of traditional Chinese, specifically, relate to a kind of medicament for the treatment of Hand-Food-Mouth Disease.

Background technology

Hand-Food-Mouth Disease is the enteric infection disease being caused by multiple enterovirus, and infectiousness is strong, propagates rapidly, passes

Broadcast approach wide, popular extensive, can cause and be very popular at short notice. Its morbidity has the trend of increasing in recent years.

Hand-Food-Mouth Disease is because severe cases early clinical manifestation is not true to type, when examining, head easily ignores, and disease progression ferociousness, once there is the breathing such as pulmonary edema, empsyxis, circulation complication, infant can be dead in the short time, brings great difficulty, the medicine treatments such as western medicine conventional Hormone, globulin, vasoactive to treatment, but these medicines be mostly treatment characterize, use these medicines after the infant death rate still higher.

The traditional Chinese medical science thinks that hand-foot-and-mouth disease is the acute infectious disease that outer heresy causes during due to hand-foot-and-mouth disease, according to this sick Characteristics of Syndromes, belong to the traditional Chinese medical science " warm disease " category, therefore according to the therapeutic principle of traditional Chinese medicine of " warm disease ", utilize clearing heat and detoxicating and clearing heat and expelling damp to add this traditional Chinese medical science unique advantage of antiviral therapy, it is very essential inventing a kind of medicament for the treatment of Hand-Food-Mouth Disease.

Summary of the invention

The object of this invention is to provide one and add this traditional Chinese medicine preparation of antiviral therapy with clearing heat and detoxicating and clearing heat and expelling damp, treatment Hand-Food-Mouth Disease, to overcome the deficiencies in the prior art.

The object of the invention is pathogenetic the recognizing to hand-foot-and-mouth disease this " warm disease " according to motherland's medical tradition medical science

Know and principle of reatment, with reference to modern pharmacological research, therefrom filter out and there is clearing heat and detoxicating, clearing heat and expelling damp and antiviral natural Chinese medicinal herb, by theory of traditional Chinese medical science prescription, make that its performance is clearing heat and detoxicating, clearing heat and expelling damp and antiviral effect, be used for the treatment of a kind of medicament of the fearful Hand-Food-Mouth Disease infecting again.

Treat a medicament for Hand-Food-Mouth Disease, it is to be made up by weight of following bulk drugs:

Honeysuckle 10-15 part, root of large-flowered skullcap 10-15 part, capsule of weeping forsythia 10-15 part, golden cypress 10-15 part, bark of official magnolia 10-15 part, Radix Isatidis 8-12 part, folium isatidis 8-12 part, Su Ye 5-10 part, wrinkled giant hyssop 5-10 part, root bark of white mulberry 3-8 part, coptis 3-8 part.

The medicament of described treatment Hand-Food-Mouth Disease, its best composition is: 15 parts of honeysuckles, 15 parts of the roots of large-flowered skullcap, 15 parts of the capsules of weeping forsythia, 12 parts of golden cypresses, 12 parts of the barks of official magnolia, 10 parts of Radix Isatidis, 10 parts of folium isatidis, 8 parts of Su Ye, 8 parts of wrinkled giant hyssops, 5 parts of the root barks of white mulberry, 3 parts of the coptiss.

Medicament of the present invention can be made various formulations with pharmaceutically acceptable carrier, such as water decoction, tablet, capsule, soft capsule, pill, granule, oral liquid or decoction etc. Can adopt preparation technique means well known in the art to complete medicine of the present invention

The preparation of agent.

In the present invention, the property of medicine of each bulk drug is as follows:

Honeysuckle: honeysuckle is cold in nature, taste is sweet, enters lung, the heart, stomach warp, has clearing heat and detoxicating, anti-inflammatory, qi-restoratives and treat effect of wind, cures mainly disease under turgor, warm disease heating, the diseases such as hot malicious large carbuncle and tumour. The illnesss such as it is dizzy for giddy, dry is done yearningly, hidrosis is unhappy, enteritis, bacillary dysentery, measles, pneumonia, encephalitis, epidemic meningitis, acute mastitis, septicemia, appendicitis, skin infection, ulcer furunculosis, erysipelas, mumps, suppurative tonsillitis all have certain curative effect. Honeysuckle is just extensive and famous with its medical value since ancient times. Its effect is mainly clearing heat and detoxicating, cures mainly warm disease heating, toxic-heat and blood stasis, ulcer serious case of furuncle etc. Modern study proves, honeysuckle contains the pharmacological component such as chlorogenic acid, cyanidenon glycosides, the various pathogens such as hemolytic streptococcus, Staphylococcus aureus and infection of the upper respiratory tract Causative virus etc. are had to stronger restraint, also can strengthen in addition immunity, anti-early pregnancy, protect liver, antitumor, anti-inflammatory, antipyretic, hemostasis (blood coagulation), suppress intestinal absorption cholesterol etc., its clinical application is very extensive, can be used for the treatment of respiratory tract infection, bacillary dysentery, acute urinary, hypertension etc. more than 40 with other medicines compatibility and plant.

The root of large-flowered skullcap: heat-clearing and damp-drying drug, purging intense heat and detonicating, hemostasis, antiabortive. Control warm heat disease, the infection of the upper respiratory tract, cough with lung heat, damp and hot jaundice, pneumonia, dysentery, hemoptysis, hot eyes, fetal irritability, hypertension, the diseases such as the swollen furuncle sore of carbuncle.

The capsule of weeping forsythia: clearing heat and detoxicating, mass dissipating and swelling eliminating. Control pyreticosis from the beginning of, anemopyretic cold, heating, vexed, abscess of throat, macula, erysipelas, scrofula, carbuncle pyogenic infections from tumour or sore, acute nephritis, heat is drenched.

Golden cypress: bitter, cold in nature, kidney, urinary bladder channel. Have heat-clearing and damp-drying drug, purging intense heat is except steaming, effect of detoxification sore treatment. For damp-heat dysentery, jaundice urine is red, the lower pruritus vulvae of band, and heat is drenched puckery pain, and beriberi impotence is preesed, hectic fever due to yin labor heat, night sweat, seminal emission, sore swollen toxin, the eczema sore that wets. Stir-baked CORTEX PHELLODENDRI with salt solution is nourishing Yin and falling fire. For fire excess from yin deficiency, night sweat hectic fever due to yin.

The bark of official magnolia: taste is pungent, warm in nature, has effect of promoting the circulation of qi dampness elimination, warming middle energizer to relieve pain, relieving asthma. Bark of official magnolia decoction has stronger antibacterial action to staphylococcus, streptococcus, dysentery characterized by blood in the stool bacillus, Pasteurella, comma bacillus; And also there is certain mitigation to striated muscle is tetanic.

Radix Isatidis: it is cold in nature, first micro-sweet rear bitterness of taste, has effect of clearing heat and detoxicating, preventing cold, relieve sore throat. Be mainly used in treating the diseases such as dark reddish purple dark, the scarlet fever of febrile virulent maculae, tongue.

Folium isatidis: bitter, cold in nature. Return liver, the heart, stomach, the spleen channel. Clearing heat and detoxicating, blood cooling and ecchymoses removing. For the high hot polydipsia of pyreticosis; Coma; Macula; Spit blood; Bleeding from five sense organs or subcutaneous tissue; Jaundice; Rush down dysentery; Erysipelas; Larynx numbness; Aphtha; Mumps.

Su Ye: nature and flavor: pungent, tepor, nontoxic. Gui Jing: the spleen channel, lung channel two warps. Have: regulate the flow of vital energy, and battalion. The chill that cures cold, fever with aversion to cold, cough, asthma, fullness and oppression of chest and abdomen, fetal irritability, and can solving toxin of fish and crab.

Wrinkled giant hyssop: pungent, tepor. Return spleen, stomach, lung channel. Have: eliminate dampness with aromatics, and middle preventing or arresting vomiting, deliver relieving summer-heat. For turbi damp obstructing in middle-JIAO, the vomiting of gastral cavity ruffian, summer-heat and damp illness that has not attacked the vital organs of the human body, damp-warm syndrome is from the beginning of, heating burnout, uncomfortable in chestly do not relax, and cold-dampness is closed heat, and stomachache is vomited and diarrhoea, nasosinusitis headache.

The root bark of white mulberry: sweet, cold. Return lung channel. Function cures mainly: removing heat from lung and relieving asthma, inducing diuresis for removing edema. For dyspnea and cough due to lung-heat, oedema turgor oliguria, appearance skin edema.

The coptis:: heat-clearing and damp-drying drug, purging intense heat and detonicating. Full for damp and hot ruffian, vomiting, rushes down dysentery, jaundice, and unconsciousness due to high fever, heart-fire hyperactivity, dysphoria and insomnia, blood-head is told nosebleed, hot eyes acid regurgitation, toothache, quenches one's thirst, the carbuncle furunculosis that swells.

Detailed description of the invention

Embodiment 1

Treat a medicament for Hand-Food-Mouth Disease, it is to press column weight amount by following bulk drugs to make:

Honeysuckle 10g, root of large-flowered skullcap 10g, capsule of weeping forsythia 10g, golden cypress 10g, bark of official magnolia 10g, Radix Isatidis 8g, folium isatidis 8g, Su Ye 5g, wrinkled giant hyssop 5g, root bark of white mulberry 3g, coptis 3g.

Adopt preparation method well known in the art to be prepared as water decoction above-mentioned raw materials medicine, the consumption that above consumption is dose.

Embodiment 2

Honeysuckle 15g, root of large-flowered skullcap 15g, capsule of weeping forsythia 15g, golden cypress 12g, bark of official magnolia 12g, Radix Isatidis 10g, folium isatidis 10g, Su Ye 8g, wrinkled giant hyssop 8g, root bark of white mulberry 5g, coptis 3g.

Adopt preparation method well known in the art to be prepared as granule above-mentioned raw materials medicine.

Embodiment 3

Honeysuckle 12g, root of large-flowered skullcap 12g, capsule of weeping forsythia 12g, golden cypress 10g, bark of official magnolia 10g, Radix Isatidis 8g, folium isatidis 8g, Su Ye 8g, wrinkled giant hyssop 8g, root bark of white mulberry 5g, coptis 5g.

Adopt preparation method well known in the art to be prepared as oral liquid above-mentioned raw materials medicine.

That the present invention has is clearing heat and detoxicating, the effect of clearing heat and expelling damp, antiviral, purging intense heat and detonicating, and a variety of causes Hand-Food-Mouth Disease is had to significant curative effect, takes through 150 people, efficiently reaches 100%, and cure rate is more than 90%.

Model case

Case 1, infant Guo, 1 year old, on October 7th, 2014, burst cough, pharynx pain, heating, aversion to wind and cold, except above-mentioned symptom, infant palm, the back of the hand, instep, vola, the visible several red papules that differ in size of pharynx rear wall, part is scratched, and has pale red secretion, is " hand-foot-and-mouth disease " after diagnosing. After taking, take embodiment 1 water decoction, every day potion, the morning, noon and afternoon service once, heat is moved back, take seven doses after state of an illness recovery from illness.

Case 2, infant Lee, 2 years old, 2015-03-09, infant hyperpyrexia, body temperature fluctuates at 38.7 DEG C-39.2 DEG C, and has brothers' fash and oral mucosa bleb in various degree, sweat is few, and rash goes out not smooth, and limbs are twitched, be diagnosed as " hand-foot-and-mouth disease ", after taking, take embodiment 1 water decoction, every day potion, the morning, noon and afternoon service once, heat is moved back, take seven doses after state of an illness recovery from illness.

Case 3, infant Liu, 5 years old, 2015-04-08, infant body temperature fluctuates at 38 DEG C-39 DEG C, and palm, the back of the hand have red papule and have brothers' fash and oral mucosa bleb in various degree, and sweat is few, rash goes out not smooth, limbs are twitched, and are diagnosed as " hand-foot-and-mouth disease ", take embodiment 1 water decoction after taking, every day potion, morning, noon and afternoon service once, and heat is moved back, take seven doses after state of an illness recovery from illness.

Claims

1. a medicament for the treatment of Hand-Food-Mouth Disease, is characterized in that, it is to be made up by weight of following bulk drugs:

2. the medicament for the treatment of Hand-Food-Mouth Disease according to claim 1, it is characterized in that, described medicament best composition is: 15 parts of honeysuckles, 15 parts of the roots of large-flowered skullcap, 15 parts of the capsules of weeping forsythia, 12 parts of golden cypresses, 12 parts of the barks of official magnolia, 10 parts of Radix Isatidis, 10 parts of folium isatidis, 8 parts of Su Ye, 8 parts of wrinkled giant hyssops, 5 parts of the root barks of white mulberry, 3 parts of the coptiss.

3. the medicament for the treatment of Hand-Food-Mouth Disease according to claim 1, is characterized in that, described medicament can be water decoction, tablet, capsule, soft capsule, pill, granule, oral liquid or decoction.