CN1055858C - Medicine for toothache - Google Patents
Medicine for toothache Download PDFInfo
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- CN1055858C CN1055858C CN96116974A CN96116974A CN1055858C CN 1055858 C CN1055858 C CN 1055858C CN 96116974 A CN96116974 A CN 96116974A CN 96116974 A CN96116974 A CN 96116974A CN 1055858 C CN1055858 C CN 1055858C
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- ethanol
- propolis
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- medicine
- milliliter
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Abstract
The present invention relates to medicine for treating toothache, which is obtained in the mode that propolis is precipitated after the propolis is extracted by 90% of ethanol, and the obtained extract fluidextract is used as main material and is assisted by metronidazole and clove oil to be remixed in 70 to 75% of ethanol. The present invention has the advantages that the pain symptom of toothache caused by periodontitis, caries inflammation, pericoronitis, etc. is obviously lightened after the medicine is applied to the local part for 2 times to 3 times, the gingiva tissue is congested within 1 day to 2 days, the edema is reduced, the bleeding is stopped, and the shape is returned to normal. The present invention has obvious effects of sterilization, inflammation elimination and analgesia, and has the advantages of fast effects, durable effects, no peculiar smell, no toxic and side effects, convenient use, safety and reliability.
Description
The present invention relates to a kind of medicine, specifically a kind of medicine tooth disease for the treatment of toothache is peaceful.
Having a toothache, disease very clinically more sees that the cause of disease is also many, as periodontitis, dental caries, pericoronitis etc.Clinical executing controlled many anti-inflammation drugs for oral administration except acupuncture, acupressure.CN1123167A, 94118075.1 disclosed a kind of be that the toothache-relieving medicinal preparation of carrier is to process with glue nurse, starch, Herba Asari, Oleum menthae, Herba Schizonepetae, Herba Eupatorii with the gum base.
The object of the present invention is to provide a kind of local application easy to use, and the toothache disease that a variety of causes causes is all had significant curative effect.
The present invention is a main and auxiliary metronidazole and Oleum Caryophylli is composite forms by peak glue extract, specifically is formulated as follows: the extract of 100～120 parts of propolis, 8～10 parts of metronidazoles and 30～40 portions of Oleum Caryophyllis are dissolved in promptly to get the tooth disease in the ethanol of 1000 parts of volumes 70～75% peaceful.When if every part of mass unit of solute is gram, then every part of volume unit of solvent is a milliliter, analogizes it, and when the former was kilogram, the latter was liter.
Propolis is the bud bud of Apis from plant, the mixture of resin, part Cera Flava and pollen that bark or the collection of stem wound come.Apis removes with it and repairs beehive crack, reinforces Nidus Vespae, dwindles and polish nest outdoors, also is used for embedding to invade the corpse of insecticide with anti-pollution Nidus Vespae.From propolis, isolated sweet multiple flavone compound now.Literature of ancient book and modern medicine monograph all have the record of propolis as medical usage.Can not directly use propolis as oral cavity medicine, must be through extracting.Extract used solvent in the present invention and be the ethanol more than 90%, heating extraction twice is separated the extracting solution that the back merges twice, and precipitation reclaims ethanol again, obtains extract flow extractum.
Metronidazole was the sick medicine of anti-trichomonal originally, and finding afterwards has curative effect preferably to anaerobic infection and amebiasis, and the stomatologist is used for anti-oral cavity infection now.
The present invention is through Affiliated Hospital of the Medical University Of Anhui department of stomatology and Anhui Chinese Medicine College Affiliated Hospital department of stomatology clinical treatment dental caries and 30 examples, pericoronitis 19 examples, periodontitis 11 example meters 60 examples, 229 tooth positions.Most patients pain after local dispenser 2～3 times obviously alleviates, and gingiva tissue hyperemia in 1～2 day, edema extinction, stopped bleeding, profile recover normal, and recurrence is not seen in the back check of two weeks.Total effective rate is more than 95%.No specific peculiar smell has no side effect.Because propolis has film property, in the oral cavity time of staying long, drug effect is subjected to the influence of saliva dilution less, so sterilization of the present invention, antiinflammatory, analgesia, not only produce effects is fast for haemostatic effect, and holds to imitate and grows.The present invention is evident in efficacy, esy to use, safe and reliable to the toothache disease, by economizing administrative department in charge of health's evaluation.
Embodiment:
One, propolis extracts:
Get 100 gram propolis, with 300 milliliter 90% ethanol heating extraction two hours, leach extracting solution, the ethanol heating extraction that reuse is 300 milliliter 90% two hours is separated, and merges extracted twice liquid, and the vacuum precipitation reclaims ethanol, obtains 100 gram propolis extraction fluid extracts.
Two, the peaceful preparation of tooth disease
1. get in the ethanol that 100 gram propolis extract fluid extracts are dissolved in 500 milliliter 70% (I), getting 8 gram metronidazoles is dissolved in 200 milliliter 70% the ethanol (II), get 30 gram Oleum Caryophyllis and be dissolved in 300 milliliter 70% the ethanol (III), with (I), (II), that (III) mixing and stirring promptly gets the tooth disease is peaceful.
2. get in the ethanol that 120 gram propolis extract fluid extracts are dissolved in 600 milliliter 75% (I), getting 10 gram metronidazoles is dissolved in 200 milliliter 75% the ethanol (II), get 40 gram Oleum Caryophyllis and be dissolved in 200 milliliter 75% the ethanol (III), with (I), (II), that (III) mixing and stirring promptly gets the tooth disease is peaceful.
3. get in the ethanol that 110 gram propolis extract fluid extracts are dissolved in 600 milliliter 75% (I), getting 9 gram metronidazoles is dissolved in 200 milliliter 70% the ethanol (II), get 35 gram Oleum Caryophyllis and be dissolved in 200 milliliter 70% the ethanol (III), with (I), (II), that (III) mixing and stirring promptly gets the tooth disease is peaceful.
4. get in the ethanol that 100 gram propolis extract fluid extracts are dissolved in 500 milliliter 75% (I), getting 10 gram metronidazoles is dissolved in 200 milliliter 70% the ethanol (II), get 40 gram Oleum Caryophyllis and be dissolved in 300 milliliter 70% the ethanol (III), with (I), (II), that (III) mixing and stirring promptly gets the tooth disease is peaceful.
5. get in the ethanol that 120 gram propolis extract fluid extracts are dissolved in 600 milliliter 70% (I), getting 8 gram metronidazoles is dissolved in 200 milliliter 75% the ethanol (II), get 30 gram Oleum Caryophyllis and be dissolved in 200 milliliter 75% the ethanol (III), with (I), (II), that (III) mixing and stirring promptly gets the tooth disease is peaceful.
6. get in the ethanol that 110 gram propolis extract fluid extracts are dissolved in 900 milliliter 70%, stir and drop into 8 gram metronidazoles and 35 gram Oleum Caryophyllis down again, add 100 milliliter 70% ethanol at last, it is peaceful promptly to get the tooth disease after the stirring and dissolving.
7. get in the ethanol that 120 gram propolis extract fluid extracts are dissolved in 900 milliliter 75%, stir and drop into 9 gram metronidazoles and 30 gram Oleum Caryophyllis down again, add 100 milliliter 75% ethanol at last, it is peaceful promptly to get the tooth disease after the stirring and dissolving.
8. get in the ethanol that 100 gram propolis extract fluid extracts are dissolved in 900 milliliter 70%, stir and drop into 10 gram metronidazoles and 38 gram Oleum Caryophyllis down, add 100 milliliter 75% ethanol at last, it is peaceful promptly to get the tooth disease after the stirring and dissolving.
Claims (1)
1. medicine for the treatment of toothache, by propolis with 90% ethanol extraction after the extract flow extractum that obtains of precipitation be main composite forming, it is characterized in that: composite in the ethanol of per 1000 parts of volumes 70～75% have 100～120 parts of propolis extracts, 8～10 parts of metronidazoles and 30～40 portions of Oleum Caryophyllis.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN96116974A CN1055858C (en) | 1996-06-21 | 1996-06-21 | Medicine for toothache |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN96116974A CN1055858C (en) | 1996-06-21 | 1996-06-21 | Medicine for toothache |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1169859A CN1169859A (en) | 1998-01-14 |
| CN1055858C true CN1055858C (en) | 2000-08-30 |
Family
ID=5123921
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN96116974A Expired - Fee Related CN1055858C (en) | 1996-06-21 | 1996-06-21 | Medicine for toothache |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1055858C (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1307977C (en) * | 2004-12-02 | 2007-04-04 | 北京正大绿洲医药科技有限公司 | Propolis dripping pills for treating toothache and its preparation method |
-
1996
- 1996-06-21 CN CN96116974A patent/CN1055858C/en not_active Expired - Fee Related
Non-Patent Citations (3)
| Title |
|---|
| 《中华口腔科杂志》1983,18(4) 1983.4.1 易新全等，来滴灵治疗牙周病的初步评价 * |
| 《辽宁中医杂志》1992,19(1) 1992.1.1 贾健等，新方治疗龋齿痛32例 * |
| 《辽宁中医杂志》1992,19(1) 1992.1.1 贾健等，新方治疗龋齿痛32例;《中华口腔科杂志》1983,18(4) 1983.4.1 易新全等，来滴灵治疗牙周病的初步评价 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1169859A (en) | 1998-01-14 |
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