CN105582412A - Compound preparation for facilitating oncothlipsis postoperative healing and preparation method thereof - Google Patents

Compound preparation for facilitating oncothlipsis postoperative healing and preparation method thereof Download PDF

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CN105582412A
CN105582412A CN201510604342.9A CN201510604342A CN105582412A CN 105582412 A CN105582412 A CN 105582412A CN 201510604342 A CN201510604342 A CN 201510604342A CN 105582412 A CN105582412 A CN 105582412A
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green onion
oncothlipsis
pearl powder
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李文龙
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Abstract

The invention discloses a compound preparation for facilitating oncothlipsis postoperative healing. The compound preparation is prepared from, by weight, 8-16 parts of astragalus membranaceus, 3-12 parts of centella, 6-12 parts of green onion, 0.2-0.6 part of pearl powder (soaked with vinegar), 6-14 parts of apples, 20-35 parts of ginseng, 6-15 parts of lucid ganoderma, 6-15 parts of angelica sinensis (processed with wine), 6-12 parts of hericium erinaceus, 3-6 parts of millet, 2-8 parts of tomatoes, 3-9 parts of malt and 5-9 parts of radix angelicae pubescentis. The compound preparation is scientific in formula, the preparation method of the dosage form is simple, and the obtained product is convenient to take and carry; in addition, the compound preparation has the good effects of being capable of taking effect more rapidly and more comprehensively, treating both symptoms and root causes, being more remarkable in curative effect and capable of effectively treating cancer pain and fever and facilitating oncothlipsis postoperative healing.

Description

A kind of compound preparation that promotes oncothlipsis hand postoperation recovery and preparation method thereof
Technical field
The present invention relates to traditional Chinese medicine field, especially relate to a kind of compound preparation that promotes oncothlipsis hand postoperation recovery and preparation method thereof.
Background technology
Medically, cancer refers to the malignant tumour that originates from epithelial tissue, is a modal class in malignant tumour. Corresponding, the malignant tumour that originates from mesenchymal tissue is referred to as sarcoma. There is minority malignant tumour to name not according to mentioned above principle, as the nephroblastoma, malignant teratoma etc. General people's said " cancer " make a general reference all malignant tumours traditionally. Tumour be body under the effect of various tumorigenesis factor, the cell of local organization loses the normal regulation of its growth is caused to paraplasm and differentiation and the neoformation that forms on gene level. Once neoformation forms, not eliminate and stop growing because of the cause of disease, his growth is not regulated by normal body physiology, but destroys normal structure and organ, and this point is especially obvious in malignant tumour. Compared with benign tumour, malignant growth speed is fast, is infiltrative growth, easily there is hemorrhage, downright bad, ulcer etc., and often have DISTANT METASTASES IN, cause that human body is become thin, unable, anaemia, poor appetite, heating and serious organ function impaired etc., finally cause death.
The cause of disease of malignant tumour is understood not yet completely. Epidemiological study for many years and experiment and clinical observation, find the have material impact of Environment and Behavior to human malignancies. Approximately more than 80% malignant tumour is relevant with environmental factor according to estimates. All-environment and hereditary carcinogenic factor may be to work in coordination with or sequential mode causes the DNA infringement of cell non-lethality, thereby activate proto-oncogene or (with) suppressor of deactivation tumour, add the change of apoptosis regulatory gene and (or) DNA-repair gene, cell is transformed. The cell being converted can first be polyclone hyperplasia, through a very long multistage evolution process, and wherein relatively unrestrictedly amplification of certain clone, pass through addition mutation, the selective subclone that forms different characteristics, infiltrates and transfer ability thereby obtain, and forms malignant tumour. Therefore, tumour is from being in essence a kind of genopathy. 1. extraneous factor (1) chemical factor: as alkylating agent, polycyclic aromatic hydrocarbons (PAH) compounds, amino azo, nitrosamines, mycotoxin and phytotoxin etc., can bring out lung cancer, cutaneum carcinoma, carcinoma of urinary bladder, liver cancer, the cancer of the esophagus and cancer of the stomach etc. (2) physical factor: ionising radiation, as x-ray can cause cutaneum carcinoma, leukaemia etc., ultraviolet ray can cause cutaneum carcinoma, and asbestos fibre is relevant with lung cancer, and talcum powder is relevant with cancer of the stomach, and all may there is canceration etc. in burn dark scar and chronic ulcer of skin. (3) biological factor: be mainly virus, wherein 1/3 is DNA virus, and 2/3 is RNA virus. DNA virus is as relevant in Epstein-Barr virus and nasopharyngeal carcinoma, Burkitt lymphoma, and human papillomavirus infection is relevant with cervical carcinoma, and hepatitis type B virus is relevant with liver cancer. RNA virus is as relevant with T chronic myeloid leukemia/lymthoma in T chronic myeloid leukemia/lymphoma virus. In addition there is also to have relation in helicobacter pylori infections and cancer of the stomach. 2. internal factor: (1) inherent cause: the real directly tumour of heredity is the uncommon tumour of minority, the effect of inherent cause in most of tumours occur is to have increased the tumorigenic tendentiousness of body and the neurological susceptibility to carcinogen, as polyposis coli, breast cancer, cancer of the stomach etc. (2) immune factor: malignant tumour easily occurs congenital or acquired immunity defect, as third kind of easy cases with leukemia of hypoproteinosis patient and lymph hematopoietic system cancer, the patient of prolonged application immunodepressant after kidney transplant, Tumor incidence is higher, but most of malignant tumours betide the crowd of immunity function " normally ", main cause is that tumour can escape immune supervision and destroy body immune system, and mechanism still imperfectly understands. (3) endocrine factors: as estrogen and prolactin and breast cancer related, the development that growth hormone can irritation cancer.
Clinical manifestation: malignant tumour?Clinical manifestation is because of organ, position and the development degree difference difference at its place, but the early stage many non-evident symptons of malignant tumour tumour, even if there is also normal atypism of symptom, while waiting patient to occur characteristic symptom, tumour has often belonged to late period. Generally the clinical manifestation of cancer is divided into topical manifestations and two aspects of general symptom. 1. the topical manifestations of cancer (1) lump: cancer cell malignant proliferation forms, and available hand touches at body surface or deep. The cancer of thyroid gland, the parotid gland or mammary gland can touch compared with superficial part position subcutaneous. Metastases to lymph node, can cause enlargement of lymph nodes, and some superficial lymph node, as cervical lymph node and axillary gland easily touch. As at health compared with cancer of the stomach, the cancer of pancreas etc. of position, deep, to firmly press just and can contact. Malignant tumour comprises that the lump growth of cancer is rapid, and air spots is sliding, is difficult for promoting; Benign tumour is general surface smoothing, as egg easy slip the same as table tennis. The thoracic organs such as lung cannot directly touch, but can see corresponding lump on rabat or CT, or touch the pleiades of transfer at the first-class position of clavicle. (2) pain: expansive growth or ulceration, the infection etc. of tumour makes nerve ending or nerve cord irriate or compressing, can occur local pain. Occur pain often point out cancer entered in, late period. Start mostly to be secret anguish or dull pain, night is obvious. Increase the weight of gradually later, become endurable, around the clock, especially obvious with night. General anodyne weak effect. (3) ulcer: body surface or GI tumour, if it is too fast to grow, can occurs necrosis or fester because scabies secondary infection forms because of blood supply insufficiency. As there is at breast place volcanic crater sample or cauliflower-like ulcer in some breast cancer, secrete courageous and upright secretion, can foul smelling taste when accompanying infection. The ulcer that stomach, colon cancer form generally only has by gastroscope, Sigmoidoscope and just can be observed. (4) hemorrhage: cancerous tissue is invaded blood vessel or the little angiorrhoxis of cancerous tissue and produced. As patients with lung cancer can be spat blood or blood-stained sputum; Cancer of the stomach, the cancer of the esophagus, colon cancer can spitting blood or are had blood in stool, and blood urine can appear in the urinary tract tumour, and cervix cancer can have colporrhagia, and Rupture of Hepatocellular Carcinoma can cause intraperitoneal hemorrhage. (5) block: cancerous tissue ramp and causing blocking of hollow organ. When region of obstruction can be had difficulty in breathing at respiratory tract, atelectasis; The cancer of the esophagus is blocked dysphagia of oesophagus; The cancer at biliary tract position can be blocked choledochus and jaundice is occurred; Carcinoma of urinary bladder urethral obstruction and occur dysuria etc.; Cancer of the stomach companion pyloric stenosis can cause Abdeminal pain, vomiting etc. after the meal. There is different symptoms in the position difference of blocking because of cancer in a word. (6) other: ICT can cause the multiple neurological symptom such as vision disorder (compressing optic nerve), facial paralysis (pressure surface nerve); Bone tumour is invaded bone can cause fracture; Liver cancer causes plasma albumin minimizing and causes ascites etc. Can there is corresponding symptom in metastases, as regional lymph nodes enlargement, lung cancer pleura shifts cancerous hydrothorax causing etc. 2. constitutional symptom: early stage malignant tumour is many without obvious constitutional symptom. The common non-specific constitutional symptom of malignant tumor patient loses weight, poor appetite, cachexia, a large amount of perspire (Sleep hyperhidrosis), anaemia, weak etc. Cachexia is often the performance of malignant tumour cachexia in late period, different parts tumour, and cachexia occurs sooner or later different, general tumor in digestive tract person can more early occur. The tumour at some position can present corresponding hyperfunction or low, and secondary general changes, and as Adrenal Pheochromocytoma causes hypertension, parathyroid adenoma causes sclerotin change etc. In addition, some tumour, as lung cancer, owing to producing endocrine substance, produces and shifts, consumes irrelevant constitutional symptom, be paraneoplastic syndrome etc., show as pulmonary osteoarthropathy, Cushing syndrome, Lambert-Eaton syndrome, dystopy ADH secretion syndrome etc.
Cancer reaches an advanced stage, and along with the increase of tumour, there will be the symptom of pressuring nerve, and some lumbar spinal column oncothlipsis nerve causes the inconvenience of walking, and need to carry out operative treatment according to patient's symptom, otherwise can feel bad very much.
At present, the traditional Chinese medical science promotes that oncothlipsis hand postoperation recovery aspect has obtained certain effect, but also has some problems: the result for the treatment of of the immunity aspect to raising patient is desirable not enough clinically; Some formula medicinal materials are numerous, and medicinal material cost is higher, is not suitable for most people and takes, and therefore needs further perfect.
Summary of the invention
For the deficiencies in the prior art, one of object of the present invention is to provide that one is prepared simply, taking convenience, portable compound preparation, to promoting oncothlipsis hand postoperation recovery to have good result for the treatment of, and can reach the immunologic function that suppresses malignant tumour breeding and raising patient.
Another object of the present invention is just to provide the preparation method of above-mentioned compound preparation.
Technical scheme of the present invention is:
Promote a compound preparation for oncothlipsis hand postoperation recovery, take off the primary raw material of stating weight proportion and be prepared from: Radix Astragali 8-16 part, centella 3-12 part, green onion 6-12 part, pearl powder (vinegar bubble) 0.2-0.6 part, apple 6-14 part, ginseng 20-35 part, glossy ganoderma 6-15 part, Radix Angelicae Sinensis (wine system) 6-15 part, Hericium erinaceus 6-12 part, millet 3-6 part, tomato 2-8 part, Fructus Hordei Germinatus 3-9 part, levisticum 5-9 part.
Promote a compound preparation for oncothlipsis hand postoperation recovery, preferred scheme is, takes off the primary raw material of stating weight proportion and is prepared from: Radix Astragali 10-14 part, centella 5-9 part, green onion 8-10 part, pearl powder (vinegar bubble) 0.3-0.5 part, apple 8-12 part, ginseng 25-30 part, glossy ganoderma 9-12 part, Radix Angelicae Sinensis (wine system) 9-13 part, Hericium erinaceus 8-10 part, millet 3-5 part, tomato 4-6 part, Fructus Hordei Germinatus 5-7 part, levisticum 6-8 part.
Promote a compound preparation for oncothlipsis hand postoperation recovery, the scheme being more preferably is, takes off the primary raw material of stating weight proportion and is prepared from: 12 parts of the Radixs Astragali, 7 parts of centellas, 9 parts of green onions, 0.4 part of pearl powder (vinegar bubble), 10 parts of apples, 28 parts of ginsengs, 10 parts of glossy ganodermas, 11 parts of Radix Angelicae Sinensis (wine system), 9 parts of Hericium erinaceuses, 4 parts of millets, 5 parts, tomato, 6 parts, Fructus Hordei Germinatus, 7 parts of levisticums.
The preparation method of described compound preparation is:
(1) green onion is cleaned and only leaves Bulbus Allii Fistulosi part, first chopping is diced again, then smash into green onion mud to pieces, green onion mud and pearl powder are mixed with the standing 1-3 hour of preservative film parcel, iron sheet is cleaned, and roasting heat, is laid in the green onion mud after mixing and pearl powder on iron plate with large iron spoon, little fire dries 5-15 minute slowly, is placed in plate stand-by;
(2) Radix Angelicae Sinensis cooking with wine is exposed to the sun under daylight 3-7 days, grinds stand-by;
(3) apple and tomato are cleaned up, after apple stripping and slicing, be placed in together with tomato in pot, add the slow 25-35 minute of stewing of fire that lards speech with literary allusions after water boil, firmly stir 2-6 minute with large iron spoon, obtain mixed liquor stand-by;
(4) Radix Astragali, centella, ginseng, glossy ganoderma, Hericium erinaceus, millet, Fructus Hordei Germinatus and levisticum are cleaned up, add and account for the raw material weight 2-4 decocting that boiled pears doubly and boil twice, each 20-40 minute that decocts, filter, merging filtrate, it is that the medicinal extract of 1.2-1.3 is stand-by that filtrate is condensed into relative density;
(5) step (1) and (4) gained are mixed, decoct while use large iron spoon to stir, in the time becoming thick paste completely, add honey, bottle and get final product wait being stirred to after honey melts completely.
The preparation method of described preparation is: step (1) mixes green onion mud and pearl powder to leave standstill 1.5-2.5 hour (preferred, green onion mud and pearl powder are mixed with standing 2 hours of preservative film parcel) with preservative film parcel.
The preparation method of described preparation is: step (1) is laid in the green onion mud after mixing and pearl powder on iron plate with large iron spoon, little fire dries 8-13 minute (preferably slowly, with large iron spoon, the green onion mud after mixing and pearl powder are laid in to iron plate upper, little fire is slow to be dried 10 minutes).
The preparation method of described preparation is: step (2) Radix Angelicae Sinensis cooking with wine is exposed to the sun under daylight 4-6 days (preferred, the Radix Angelicae Sinensis cooking with wine is exposed to the sun 5 days under daylight).
The preparation method of described preparation is: step (3) adds the slow 28-23 minute of stewing of fire that lards speech with literary allusions after water boil, firmly stirs 3-5 minute (preferred, add the slow stewing of fire 30 minutes of larding speech with literary allusions after water boil, firmly stir 4 minutes with large iron spoon) with large iron spoon.
The preparation method of described preparation is: step (4) adds and accounts for the raw material weight 2.5-3.5 decocting that boiled pears doubly and boil twice, decoct 25-35 minute (preferably at every turn, add the decocting that boiled pears that accounts for 3 times of raw material weights to boil twice, decoct 30 minutes at every turn).
The preparation method of described preparation is: filtrate is condensed into the medicinal extract that relative density is 1.23-1.28 (preferred, it is 1.25 medicinal extract that filtrate is condensed into relative density) by step (4).
The pharmacology of the present invention's main Chinese medicine material used is as follows:
The Radix Astragali: be distributed in the ground such as park of Argentina, Brazil south, Uruguay and China's Mainland, be often born in ease raw, originate in South America. Sun plant all herbal medicine, has clearing heat and detoxicating, promoting blood circulation, swelling and pain relieving, the function such as anticancer. Taste acid cold in nature, herb is containing compositions such as multivitamin, trace element and amino acid. There is removing pattogenic heat from the blood and toxic material from the body, blood stasis removing analgesic, effect of detumescence and clearing heat and promoting diuresis. Have clearing heat and detoxicating, promoting blood circulation and removing blood stasis, swelling and pain relieving, anticancer effect; Appendicitis curing, hepatitis, stomachache, early liver cancer, lung cancer, cervix cancer, mastitis etc.; External application is controlled pain furuncle and is treated, the diseases such as treating swelling and pain by traumatic injury. This medicine large usage quantity among the people.
Centella: be dry herb or the whole herb with root of dicotyledon Umbelliferae centella. Composition: containing the Triterpenoid of multiple α-amyrin type, wherein have asiaticosid, thankuniside, isothankuniside, madecassoside, Brahmoside, broken heat rice glycosides and Brahmic acid etc., and madasiatic acid. The property of medicine: bitter, acrid, cold. Return liver,spleen,kidney warp. Function cures mainly: clearing heat and detoxicating, inducing diuresis and reducing edema. Be Asians's long-lived medicine, can refresh oneself by beneficial brain. Research shows to have nourishing, anti-inflammatory, healing of wound, diuresis defaecation and calm effect. Also effective in cure to leprosy, ulcer, blood purification and immunity are had to activation, because it can stimulate the replacement of deep skin cell. It is neural nourishing agent, can improve memory, alleviates mental fatigue; Also can be hypotensive, treatment hepatopathy etc.
Green onion: another name and thing grass, onion, dish primary, fiery green onion, the four seasons green onion. Flavor efficacy is pungent, and temperature enters lung, stomach warp. Outer real hollow, rises to fall more and lacks, and merit is specially dispersed and activated yang, can expelling wind and cold pathogens, and sweating expelling pathogenic factors from muscles and skin, is used for the treatment of the light disease of typhoid fever, fever and chills headache; Again can item, sharp key, defaecation, activate yang gas and loose cold sensation of the genitalia is used for the treatment of qi and blood cohesion, dizzy headache, cold obstruction causing qi stagnation, abdominal distension stomachache, and bladder qi dysfunction and difficult urination etc.; In addition still tool removing toxic substances, hemostatic function. Energy activating yang to invigorate blood circulation, expelling parasite removing toxic substances, inducing sweat and dispelling exogenous evils. Cure mainly the illnesss such as the light disease of anemofrigid cold, carbuncle sore tumefacting virus, dysentery weak pulse, cold solidifying stomachache, difficult urination, flu, chill, headache, cold sensation of the genitalia stomachache, malnutrition due to parasitic infestation internal resistance, dysentery etc. are had to good therapeutic action. 1. antipyretic, eliminate the phlegm: the volatilization wet goods active ingredient of green onion, there is the health of stimulation sweat gland, reach the effect of sweating heat radiation; Scallion oil stimulates the upper respiratory tract, makes sticky phlegm be easy to bring up. 2. promote to digest and assimilate: green onion stimulates the effect of body digestive juice secretion in addition, can spleen benefiting and stimulating the appetite, improve a poor appetite. 3. antibacterial, antiviral 4. cancer-resistings.
Pearl powder: strengthen that immunity, supplement calcium, Bao Chunyan decline, improvement is slept, treat ulcer, nourish the liver to improve visual acuity, secondary buck. Pearl powder for oral administration is treated the effects such as pharyngitis, treatment constipation and row's endogenous toxic material, treatment arrhythmia cordis, supplemental treatment diabetes B, treatment gynaecological disease in addition, and these effects have all obtained confirmation in modern medicine. Pearl powder can promote the growth of collagenocyte in human body, and collagenocyte is the main person who has rendered outstanding service who impels skin regeneration, and pearl powder also has more significant antiinflammation simultaneously, can inflammation-inhibiting cytothesis, prevent that wound from further worsening. Pearl powder is outer can fill tissue space for wound, and adhesion vascular tissue brings into play its anti-inflammatory, promotes effect that collagenocyte is grown, and impels body cell regeneration.
Apple: apple not only can regulate functions of intestines and stomach, reduces cholesterol, hypotensive, anti-cancer, and fat-reducing, can also strengthen children's memory. Apple not only contains multivitamin, lipid, and mineral matter, carbohydrates etc. form the necessary nutrition of brain, and can also strengthen the zinc of children's memory containing the fine fibre that is conducive to upgrowth and development of children. Zinc is to form and closely bound up nucleic acid and the requisite element of albumen of memory, and scarce zinc can make the depauperation of cerebral cortex edge part hippocampus. In order to make our memory good, advise our should be the rationally suitable apple that eats of more. Apple nutritive value: apple has the laudatory title of " wisdom fruit ", " fruit good for memory ". People find for a long time, eat apple more and have the memory of enhancement, improve intelligent effect. According to the study, zinc is the part of many important enzymes in human body, is the key element of enhancing development. Zinc is by the metabolism of enzyme wide participation body internal protein, fat and sugar. Zinc still forms the requisite element of the nucleic acid closely bound up with memory and protein. Scarce zinc can make the depauperation of cerebral cortex edge part hippocampus, affects memory, and experiment also proves, reduces the zinc in food, and child's memory and learning ability are subject to serious hindrance. Zinc also has substantial connection with generation antibody, raising body immunity etc.
Ginseng: ginseng is described as the superfine product of " kings of hundred grass " " enriching yin is mended raw; strengthen the body resistance to consolidate the constitution " from ancient times, containing multiple saponin and polysaccharide composition, leachate can be by the slow absorption of skin and without pessimal stimulation, energy skin expansion capillary, promote skin blood circulation, increase skin-nourishing, the water oil balance of regulation of skin, prevents skin dehydration, sclerosis, wrinkling, the reducing property of ginseng active material check melanin, make skin pure white smooth, can strengthen skin elasticity, cell be obtained newborn, be the superfine product of improving looks. The fleshy root of ginseng is famous strong tonic, is applicable to adjust blood pressure, recovers cardiac function, neurasthenia and the disease such as in poor health, also eliminates the phlegm, the effect such as stomach invigorating, diuresis, excitement.
Glossy ganoderma: glossy ganoderma (formal name used at school: GanodermaLucidumKarst), profile is umbrella, and cap kidney shape, semicircle or subcircular are the fructification of On Polyporaceae glossy ganoderma. There is invigorating qi for tranquilization, relieving cough and asthma effect, cough and breathe heavily for dizzy egersis, palpitation, consumptive disease. That glossy ganoderma is that one has is crease-resistant, anti-inflammatory, removing color spot, protection skin. The composition that glossy ganoderma contains check melanin and the multiple trace element to skin beneficiating etc., these compositions can be by reducing human free radical, accelerate the regeneration of cell, increase the thickness of skin and increase collagen, reach the effect of plump skin, elimination microgroove and wrinkle. Polysaccharide component wherein can, by keeping and regulation of skin water-based, recover skin elasticity, makes skin wet, exquisiteness.
Radix Angelicae Sinensis: enrich blood; Invigorate blood circulation; Menstruction regulating and pain relieving; Moisturize laxation. The all cards of the main deficiency of blood; Irregular menstruation; Through closing; Dysmenorrhoea; Abdominal mass knot is poly-; Uterine bleeding; Asthenia cold abdominalgia; Impotence numbness; Numbness; Intestines are dry just difficult; Heavy after dysentery characterized by blood in the stool; Ulcer sores; Injury from falling down, Radix Angelicae Sinensis taste is sweet and weigh, therefore specially can enrich blood, for first medicine of enriching blood, be applicable to pale or sallow complexion, lassitude hypodynamia, lip and nail due to heart-liver blood deficiency card light simple and unadorned, have a dizzy spell, the disease such as palpitation and insomnia, Radix Angelicae Sinensis can be widely used in various tumours, especially gynecological tumor, with qi and blood stagnate, cohesion person is the most suitable for hemostasis. To the patient of deficiency of vial QI after the thin thin middle and terminal cancer of the deficiency of blood or operation, radiotherapy, chemotherapy, also can select Radix Angelicae Sinensis, with right supporting anticancer.
Hericium erinaceus: be the fructification of hedgehog fungus section Hericium fungi Hericium erinaceus, Hydnum. Composition: contain Hericium erinaceus (Bull. Ex Fr.) Pers. Ketone A, B, C, D, E, F, G, H, Hericium erinaceus alkali etc. in Hericium erinaceus. Dry fructification is containing protein, lipid, fiber and glucan. Also containing sterols: ergosterol etc. Mycelium culture contains Hericium erinaceus pyrones A, B etc. The property of medicine: " national Chinese herbal medicine compilation ": " sweet, flat. " function cures mainly: strengthening spleen and nourishing stomach, calm the nerves, anticancer. Cure mainly body void weak, indigestion, insomnia, gastroduodenal ulcer, chronic gastritis, tumor in digestive tract.
Millet: the traditional Chinese medical science thinks that health basis is essence, gas, god. Essence is virility, and gas is Source of life, and god is the light of life. Essence, gas, refreshing each tool function, interact again. Tcm health preserving is mainly to take good care of essence, gas, god. Five cereals are the elite of taking good care of essence, gas, god. According to the theory of integration of drinking and medicinal herbs, five cereals are natural, the most pure medicines, Fructus Hordei Germinatus energy tonifying primordial Qi, and millet can be anti-ageing, and mung bean can be antitumor, the rice gas of establishing the yang function. " Mingyi Bielu " once described effect of Fructus Hordei Germinatus like this: kidney-nourishing gas, removes spleen pathogenic heat in the stomach, beneficial gas. Li Shizhen (1518-1593 A.D.) is write: the taste degree of saltiness of grain (Fructus Hordei Germinatus), and gas cold purgation is oozed, and also, ephrosis is easily eaten it to the paddy of kidney. Stomach fire is fallen, therefore the disease of taste should be eaten it. According to assay, the contained nutritional labeling of Fructus Hordei Germinatus, up to 18 kinds more than, contains 17 seed amino acids, wherein 8 kinds of essential amino acids, and amino acid can promote the secretion of human body epiphysin, thereby edible malt soup can play the effect of hypnosis, health care, beauty treatment.
Tomato: tomato nutrient is abundant, tool flavour. There is weight-reducing, eliminate fatigue, improve a poor appetite, improve the effect such as digestion, minimizing gasteremphraxis dyspepsia to protein. Tomato has hemostasis, step-down, diuresis, stomach strengthening and digestion promoting, promotes the production of body fluid to quench thirst, effect of the flat liver of clearing heat and detoxicating, cool blood. Because vitamin A in tomato, ascorbic ratio are suitable, can strengthen little vascular function so often eat, prevention blood vessel aging. Flavonoids in tomato, the permeability of existing reduction capillary and prevent from the effect that it breaks from preventing in addition angiosclerotic special efficacy, can prevent the diseases such as cervical carcinoma, carcinoma of urinary bladder and cancer of pancreas; In addition, can also improve looks and cure aphtha (can contain a little tomato juices, make its contact sore face, every number of times minute, every day, effect was remarkable for several times).
Fructus Hordei Germinatus: return spleen, stomach warp. Effect: promote qi circulation digestion promoting, spleen benefiting and stimulating the appetite, delaactation dissipate-swelling. Cure mainly: do not disappear for dyspepsia, abdominal distention, insufficiency of the spleen food is few, and milk smoulders, swollen breasts, women's ablactation, liver-depressed hypochondrium pain, stomachache due to emotional depression and the hyperactive liver-qi attacking the stomach.
Levisticum: be the root of the heavy tooth Radix Angelicae Sinensis of Umbelliferae archangel. Composition: containing coumarin kind compound, volatile oil, acetic acid esters, angelol, Thymol. Pharmacology: cardiovascular system is played a very important role, have the effect of step-down, can promote hematoblastic gathering, there is good analgesia and antiinflammatory action. There is anti-light quick effect, opposing tumour is had to significant curative effect, anti-inflammation is also played a very important role. The property of medicine: hardship, tepor, pungent. Return kidney, urinary bladder channel. Function cures mainly: expelling wind and eliminating dampness, eliminating cold to stop pain.
Compound preparation prescription science provided by the invention, the preparation method of formulation is simple, make products obtained therefrom taking convenience, be easy to carry, in addition, excellent results of the present invention also shows: effect sooner, more comprehensively, treat both principal and secondary aspect of disease, more remarkable treatment effect and this compound preparation, can effectively treat pain caused by cancer, heating and promote oncothlipsis hand postoperation recovery.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited to this.
1 one kinds of embodiment promote the compound preparation of oncothlipsis hand postoperation recovery, take off the primary raw material of stating weight proportion and are prepared from (getting 10g for every part): 12 parts of the Radixs Astragali, 7 parts of centellas, 9 parts of green onions, 0.2 part of pearl powder (vinegar bubble), 10 parts of apples, 28 parts of ginsengs, 10 parts of glossy ganodermas, 11 parts of Radix Angelicae Sinensis (wine system), 9 parts of Hericium erinaceuses, 4 parts of millets, 5 parts, tomato, 6 parts, Fructus Hordei Germinatus, 7 parts of levisticums.
The preparation method of above-mentioned compound preparation is:
(1) green onion is cleaned and only leaves Bulbus Allii Fistulosi part, first chopping is diced again, then smash into green onion mud to pieces, green onion mud and pearl powder are mixed and leave standstill 1 hour with preservative film parcel, iron sheet is cleaned, and roasting heat, is laid in the green onion mud after mixing and pearl powder on iron plate with large iron spoon, little fire is slow to be dried 5 minutes, is placed in plate stand-by;
(2) Radix Angelicae Sinensis cooking with wine is exposed to the sun 3 days under daylight, grinds stand-by;
(3) apple and tomato are cleaned up, after apple stripping and slicing, be placed in together with tomato in pot, add and lard speech with literary allusions that fire is slow to be simmered 25 minutes after water boil, firmly stir 2 minutes with large iron spoon, obtain mixed liquor stand-by;
(4) Radix Astragali, centella, ginseng, glossy ganoderma, Hericium erinaceus, millet, Fructus Hordei Germinatus and levisticum are cleaned up, add the decocting that boiled pears that accounts for 2 times of raw material weights to boil twice, decoct 20 minutes at every turn, filter, merging filtrate, it is that 1.2 medicinal extract is stand-by that filtrate is condensed into relative density;
(5) step (1) and (4) gained are mixed, decoct while use large iron spoon to stir, in the time becoming thick paste completely, add honey, bottle and get final product wait being stirred to after honey melts completely.
Model case one: Zhao XX, the age: 56 years old, sex: man, people from Jinan City, Shandong Province, symptom: just started some pain of liver, upper abdomen enclosed mass, receive poor, weak, become thin, generate heat, suffer from diarrhoea, suffer from abdominal pain, right shoulder is ached etc., melena, spitting blood, be diagnosed as liver cancer in mid-term through examination in hospital, sick age: 6 months, in these 6 months, due to the diffusion of tumour, lumbar spinal column oncothlipsis nerve causes the inconvenience of walking, and treats through operation, postoperatively takes compound preparation of the present invention.
Take the present embodiment 1 gained compound preparation, take 10 days, operation healing fine, and very good of spirit, appetite increases, and patient takes compound preparation always, and immunity strengthens, and has effectively suppressed cancer cell diffusion, promotes oncothlipsis hand postoperation recovery.
2 one kinds of embodiment promote the compound preparation of oncothlipsis hand postoperation recovery, take off the primary raw material of stating weight proportion and are prepared from (getting 20g for every part): 12 parts of the Radixs Astragali, 7 parts of centellas, 9 parts of green onions, 0.6 part of pearl powder (vinegar bubble), 10 parts of apples, 28 parts of ginsengs, 10 parts of glossy ganodermas, 11 parts of Radix Angelicae Sinensis (wine system), 9 parts of Hericium erinaceuses, 4 parts of millets, 5 parts, tomato (vinegar bubble), 6 parts, Fructus Hordei Germinatus, 7 parts of levisticums.
The preparation method of above-mentioned compound preparation is:
(1) green onion is cleaned and only leaves Bulbus Allii Fistulosi part, first chopping is diced again, then smash into green onion mud to pieces, green onion mud and pearl powder are mixed and leave standstill 3 hours with preservative film parcel, iron sheet is cleaned, and roasting heat, is laid in the green onion mud after mixing and pearl powder on iron plate with large iron spoon, little fire is slow to be dried 15 minutes, is placed in plate stand-by;
(2) Radix Angelicae Sinensis cooking with wine is exposed to the sun 7 days under daylight, grinds stand-by;
(3) apple and tomato are cleaned up, after apple stripping and slicing, be placed in together with tomato in pot, add and lard speech with literary allusions that fire is slow to be simmered 35 minutes after water boil, firmly stir 6 minutes with large iron spoon, obtain mixed liquor stand-by;
(4) Radix Astragali, centella, ginseng, glossy ganoderma, Hericium erinaceus, millet, Fructus Hordei Germinatus and levisticum are cleaned up, add the decocting that boiled pears that accounts for 4 times of raw material weights to boil twice, decoct 40 minutes at every turn, filter, merging filtrate, it is that 1.3 medicinal extract is stand-by that filtrate is condensed into relative density;
(5) step (1) and (4) gained are mixed, decoct while use large iron spoon to stir, in the time becoming thick paste completely, add honey, bottle and get final product wait being stirred to after honey melts completely.
3 one kinds of embodiment promote the compound preparation of oncothlipsis hand postoperation recovery, take off the primary raw material of stating weight proportion and are prepared from (every part of 30g): 12 parts of the Radixs Astragali, 7 parts of centellas, 9 parts of green onions, 0.3 part of pearl powder (vinegar bubble), 10 parts of apples, 28 parts of ginsengs, 10 parts of glossy ganodermas, 11 parts of Radix Angelicae Sinensis (wine system), 9 parts of Hericium erinaceuses, 4 parts of millets, 5 parts, tomato, 6 parts, Fructus Hordei Germinatus, 7 parts of levisticums.
The preparation method of above-mentioned compound preparation is:
(1) green onion is cleaned and only leaves Bulbus Allii Fistulosi part, first chopping is diced again, then smash into green onion mud to pieces, green onion mud and pearl powder are mixed and leave standstill 1.5 hours with preservative film parcel, iron sheet is cleaned, and roasting heat, is laid in the green onion mud after mixing and pearl powder on iron plate with large iron spoon, little fire is slow to be dried 8 minutes, is placed in plate stand-by;
(2) Radix Angelicae Sinensis cooking with wine is exposed to the sun 4 days under daylight, grinds stand-by;
(3) apple and tomato are cleaned up, after apple stripping and slicing, be placed in together with tomato in pot, add and lard speech with literary allusions that fire is slow to be simmered 28 minutes after water boil, firmly stir 3 minutes with large iron spoon, obtain mixed liquor stand-by;
(4) Radix Astragali, centella, ginseng, glossy ganoderma, Hericium erinaceus, millet, Fructus Hordei Germinatus and levisticum are cleaned up, add the decocting that boiled pears that accounts for 2.5 times of raw material weights to boil twice, decoct 25 minutes at every turn, filter, merging filtrate, it is that 1.23 medicinal extract is stand-by that filtrate is condensed into relative density;
(5) step (1) and (4) gained are mixed, decoct while use large iron spoon to stir, in the time becoming thick paste completely, add honey, bottle and get final product wait being stirred to after honey melts completely.
4 one kinds of embodiment promote the compound preparation of oncothlipsis hand postoperation recovery, take off the primary raw material of stating weight proportion and are prepared from (every part of 40g): 12 parts of the Radixs Astragali, 7 parts of centellas, 9 parts of green onions, 0.5 part of pearl powder (vinegar bubble), 10 parts of apples, 28 parts of ginsengs, 10 parts of glossy ganodermas, 11 parts of Radix Angelicae Sinensis (wine system), 9 parts of Hericium erinaceuses, 4 parts of millets, 5 parts, tomato, 6 parts, Fructus Hordei Germinatus, 7 parts of levisticums.
The preparation method of above-mentioned compound preparation:
(1) green onion is cleaned and only leaves Bulbus Allii Fistulosi part, first chopping is diced again, then smash into green onion mud to pieces, green onion mud and pearl powder are mixed with the standing 1-3 hour of preservative film parcel, iron sheet is cleaned, and roasting heat, is laid in the green onion mud after mixing and pearl powder on iron plate with large iron spoon, little fire dries 5-15 minute slowly, is placed in plate stand-by;
(2) Radix Angelicae Sinensis cooking with wine is exposed to the sun under daylight 3-7 days, grinds stand-by;
(3) apple and tomato are cleaned up, after apple stripping and slicing, be placed in together with tomato in pot, add the slow 25-35 minute of stewing of fire that lards speech with literary allusions after water boil, firmly stir 2-6 minute with large iron spoon, obtain mixed liquor stand-by;
(4) Radix Astragali, centella, ginseng, glossy ganoderma, Hericium erinaceus, millet, Fructus Hordei Germinatus and levisticum are cleaned up, add and account for the raw material weight 2-4 decocting that boiled pears doubly and boil twice, each 20-40 minute that decocts, filter, merging filtrate, it is that the medicinal extract of 1.2-1.3 is stand-by that filtrate is condensed into relative density;
(5) step (1) and (4) gained are mixed, decoct while use large iron spoon to stir, in the time becoming thick paste completely, add honey, bottle and get final product wait being stirred to after honey melts completely.
Model case two: ancient sacrificial utensil XX, the age: 50 years old, sex: man, the regular secret anguish of stomach, belch, vomiting, do not have appetite, health is become thin weak, going to hospital to make a definite diagnosis is cancer of the stomach mid-term, adopts chemotherapeutic treatment 3 months, in these 3 months, due to the diffusion of tumour, lumbar spinal column oncothlipsis nerve causes the inconvenience of walking, and treats through operation, postoperatively takes compound preparation of the present invention.
Take the present embodiment 4 gained compound preparations, take 7 days, operation healing fine, and very good of spirit, appetite increases, and patient takes compound preparation always, and immunity strengthens, and has effectively suppressed cancer cell diffusion, promotes oncothlipsis hand postoperation recovery.
5 one kinds of embodiment promote the compound preparation of oncothlipsis hand postoperation recovery, take off the primary raw material of stating weight proportion and are prepared from (every part of 50g): 12 parts of the Radixs Astragali, 7 parts of centellas, 9 parts of green onions, 0.4 part of pearl powder (vinegar bubble), 10 parts of apples, 28 parts of ginsengs, 10 parts of glossy ganodermas, 11 parts of Radix Angelicae Sinensis (wine system), 9 parts of Hericium erinaceuses, 4 parts of millets, 5 parts, tomato, 6 parts, Fructus Hordei Germinatus, 7 parts of levisticums.
The preparation method of above-mentioned compound preparation is:
(1) green onion is cleaned and only leaves Bulbus Allii Fistulosi part, first chopping is diced again, then smash into green onion mud to pieces, green onion mud and pearl powder are mixed and leave standstill 2 hours with preservative film parcel, iron sheet is cleaned, and roasting heat, is laid in the green onion mud after mixing and pearl powder on iron plate with large iron spoon, little fire is slow to be dried 10 minutes, is placed in plate stand-by;
(2) Radix Angelicae Sinensis cooking with wine is exposed to the sun 5 days under daylight, grinds stand-by;
(3) apple and tomato are cleaned up, after apple stripping and slicing, be placed in together with tomato in pot, add and lard speech with literary allusions that fire is slow to be simmered 30 minutes after water boil, firmly stir 4 minutes with large iron spoon, obtain mixed liquor stand-by;
(4) Radix Astragali, centella, ginseng, glossy ganoderma, Hericium erinaceus, millet, Fructus Hordei Germinatus and levisticum are cleaned up, add the decocting that boiled pears that accounts for 3 times of raw material weights to boil twice, decoct 30 minutes at every turn, filter, merging filtrate, it is that 1.25 medicinal extract is stand-by that filtrate is condensed into relative density;
(5) step (1) and (4) gained are mixed, decoct while use large iron spoon to stir, in the time becoming thick paste completely, add honey, bottle and get final product wait being stirred to after honey melts completely.
The clinical practice of test example 1 embodiment 5 gained compound preparations: screen 400 routine patients in 4 hospitals, wherein women's 200 examples, the male sex's 200 examples, test 2 weeks before, carries out Continuous Observation to this crowd, records symptom and variation, be divided at random two groups, experimental group and control group, experimental group is taken embodiment 5 products obtained therefroms, and control group is taken other medicine (medicine such as safe peace oral liquid, holy liquid oral liquid).
Using method is: getting 10g at every turn, take half an hour after meal, bubble open with hot water, 10 days is a course for the treatment of.
Curative effect situation criterion: effectively: take after this product, malaise symptoms disappears, energy and muscle power obviously strengthen; Invalid: take after this product, malaise symptoms is unchanged, resultAs table 1Shown in.
Table 1
Self-induction symptom during takingAs table 2Shown in.
Table 2
The present invention selects the Radix Astragali, centella, green onion, pearl powder, apple etc. to carry out compatibility, make medicine produce synergy, the more effective promotion oncothlipsis hand postoperation recovery of energy, and can improve patient's immunity, take 60 days, more than 95% feeling takes a turn for the better to some extent, and immunity obviously strengthens, and spirit, muscle power strengthen.

Claims (10)

1. a compound preparation that promotes oncothlipsis hand postoperation recovery, is characterized in that: take off and state the main of weight proportionRaw material is prepared from: Radix Astragali 8-16 part, and centella 3-12 part, green onion 6-12 part, pearl powder (vinegar bubble) 0.2-0.6 part,Apple 6-14 part, ginseng 20-35 part, glossy ganoderma 6-15 part, Radix Angelicae Sinensis (wine system) 6-15 part, Hericium erinaceus 6-12 part, littleRice 3-6 part, tomato 2-8 part, Fructus Hordei Germinatus 3-9 part, levisticum 5-9 part.
2. the compound preparation of promotion oncothlipsis hand postoperation recovery according to claim 1, is characterized in that: take offThe primary raw material of stating weight proportion is prepared from: Radix Astragali 10-14 part, centella 5-9 part, green onion 8-10 part, pearl powder (vinegarBubble) 0.3-0.5 part, apple 8-12 part, ginseng 25-30 part, glossy ganoderma 9-12 part, Radix Angelicae Sinensis (wine system) 9-13 part, monkeyBacterium 8-10 part, millet 3-5 part, tomato 4-6 part, Fructus Hordei Germinatus 5-7 part, levisticum 6-8 part.
3. the compound preparation of promotion oncothlipsis hand postoperation recovery according to claim 1, is characterized in that: take offThe primary raw material of stating weight proportion is prepared from: 12 parts of the Radixs Astragali, 7 parts of centellas, 9 parts of green onions, pearl powder (vinegar bubble) 0.4Part, 10 parts of apples, 28 parts of ginsengs, 10 parts of glossy ganodermas, 11 parts of Radix Angelicae Sinensis (wine system), 9 parts of Hericium erinaceuses, 4 parts of millets,5 parts, tomato, 6 parts, Fructus Hordei Germinatus, 7 parts of levisticums.
4. according to the preparation method who promotes the compound preparation of oncothlipsis hand postoperation recovery described in claim 1-3 any one,It is characterized in that: step is as follows:
(1) green onion is cleaned and only leaves Bulbus Allii Fistulosi part, first chopping is diced again, then smashs into green onion mud to pieces, by green onion mud and pearlPowder mixes and leaves standstill 1-3 hour with preservative film parcel, iron sheet is cleaned, roasting heat, with large iron spoon by green onion mud and pearl after mixingIt is upper that powder is laid in iron plate, and little fire dries 5-15 minute slowly, is placed in plate stand-by;
(2) Radix Angelicae Sinensis cooking with wine is exposed to the sun under daylight 3-7 days, grinds stand-by;
(3) apple and tomato are cleaned up, after apple stripping and slicing, be placed in together with tomato in pot, turn after adding water boilSlow fire is simmered 25-35 minute slowly, firmly stirs 2-6 minute with large iron spoon, obtains mixed liquor stand-by;
(4) Radix Astragali, centella, ginseng, glossy ganoderma, Hericium erinaceus, millet, Fructus Hordei Germinatus and levisticum are cleaned up, add and account forThe raw material weight 2-4 decocting that boiled pears doubly boils twice, decocts 20-40 minute at every turn, filters, and merging filtrate, by filtrateThe medicinal extract that is condensed into relative density and is 1.2-1.3 is stand-by;
(5) step (1) and (4) gained are mixed, decoct while use large iron spoon to stir, treat to become completely thick pasteTime add honey, bottle and get final product wait being stirred to after honey melts completely.
5. the preparation method of preparation is according to claim 4: it is characterized in that: step (1) is by green onion mud and pearl powderMix with preservative film and wrap up and (preferably, green onion mud and pearl powder being mixed with preservative film parcel standing 2 for standing 1.5-2.5 hourHour).
6. the preparation method of preparation is according to claim 4: it is characterized in that: step (1) will mix with large iron spoonAfter green onion mud and pearl powder to be laid in iron plate upper, little fire dry slowly 8-13 minute (preferred, with large iron spoon by the green onion after mixingIt is upper that mud and pearl powder are laid in iron plate, and little fire is slow to be dried 10 minutes).
7. the preparation method of preparation is according to claim 4: it is characterized in that: step (2) will cook with wineRadix Angelicae Sinensis be exposed to the sun under daylight 4-6 days (preferred, the Radix Angelicae Sinensis cooking with wine is exposed to the sun 5 days under daylight).
8. the preparation method of preparation is according to claim 4: it is characterized in that: after step (3) adds water boil, lard speech with literary allusionsThe slow 28-23 minute that simmers of fire, with large iron spoon firmly stir 3-5 minute (preferred, add 30 points of the slow stewings of fire of larding speech with literary allusions after water boilClock, firmly stirs 4 minutes with large iron spoon).
9. the preparation method of preparation is according to claim 4: it is characterized in that: step (4) adds and accounts for raw material weightThe 2.5-3.5 decocting that boiled pears doubly boils twice, decocts at every turn and (preferably, adds and account for 3 times of raw material weights for 25-35 minuteThe decocting that boiled pears boil twice, decoct 30 minutes at every turn).
10. the preparation method of preparation is according to claim 4: it is characterized in that: step (4) is condensed into filtrateRelative density is the medicinal extract (preferred, it is 1.25 medicinal extract that filtrate is condensed into relative density) of 1.23-1.28.
CN201510604342.9A 2015-09-21 2015-09-21 Compound preparation for facilitating oncothlipsis postoperative healing and preparation method thereof Pending CN105582412A (en)

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