CN105582257A - 一种治疗肝肾阴虚型视神经萎缩的中药制剂 - Google Patents

一种治疗肝肾阴虚型视神经萎缩的中药制剂 Download PDF

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CN105582257A
CN105582257A CN201510973577.5A CN201510973577A CN105582257A CN 105582257 A CN105582257 A CN 105582257A CN 201510973577 A CN201510973577 A CN 201510973577A CN 105582257 A CN105582257 A CN 105582257A
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姜良军
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Abstract

本发明公开了一种治疗肝肾阴虚型视神经萎缩的中药制剂，属于中药技术领域。发明人在多年的临床实践中，应用中医学理论，针对肝肾阴虚型视神经萎缩的发病机理，选择中药夏枯草、密蒙花、茱苓草、满天星、蜜柑草、枸杞子、楮实、野大豆藤、龙船花、凤尾七、狗尾巴参、向阳花，水煎成汤剂，经临床试验，总有效率达到90％。

Description

一种治疗肝肾阴虚型视神经萎缩的中药制剂
技术领域
本发明涉及一种中药组合物，尤其涉及一种治疗肝肾阴虚型视神经萎缩的中药制剂。
背景技术
视神经萎缩是指任何疾病引起视网膜神经节细胞及其轴突发生退行性病变，致使视盘颜色变淡或苍白，视功能严重障碍。目前治疗视神经萎缩仍无特效方法，对本病的治疗，西医学多认为其为一种不可逆的损害，故无特殊治疗方法，常采用补充维生素和能量合剂以营养视神经，效果不理想。而近年来，一些研究表明，萎缩之视神经可以再生。随着神经眼科学研究的迅速发展，运用中医治疗视神经萎缩已逐渐得到重视。在临床应用方面，中医学对本病的治疗具有较为丰富的经验和比较完整的理论，可依据病因，辩证施治，对症下药，不但疗效显著，而且中药药源丰富、应用安全。
发明内容
本发明的目的是提供一种治疗肝肾阴虚型视神经萎缩的中药制剂。视神经萎缩在我国医学领域属于“视瞻混秒”“视瞻有色”“青盲”的范畴。辩证治疗肝肾阴虚型视神经萎缩宜补益肝肾，开窍明目。
本发明的目的是通过以下技术方案实现的，该治疗肝肾阴虚型视神经萎缩的中药制剂由以下重量份的中药制成：夏枯草10-16份、密蒙花6-12份、茱苓草9-14份、满天星12-18份、蜜柑草25-35份、枸杞子10-16份、楮实8-14份、野大豆藤50-60份、龙船花14-20份、凤尾七7-11份、狗尾巴参12-18份、向阳花12-16份。
优选的：夏枯草13份、密蒙花9份、茱苓草11份、满天星15份、蜜柑草30份、枸杞子13份、楮实11份、野大豆藤55份、龙船花18份、凤尾七9份、狗尾巴参15份、向阳花14份。
将上述中药按传统方法制成汤剂。
方中：夏枯草清肝散结；密蒙花祛风凉血、润肝明目；茱苓草调经活血、清热明目；满天星清热明目、消肿；蜜柑草清热明目、健胃；枸杞子滋肾润肺、补肝明目；楮实滋肾清肝、明目；野大豆藤平肝健脾；龙船花清肝活血、止痛；凤尾七补肾、养心安神、调经活血、明目；狗尾巴参养阴润肺、生津益气；向阳花清肝明目。
临床资料
1、一般资料80例均为门诊确诊为视神经萎缩患者，随机分为治疗组40例，男19例，女21例；年龄17～58岁，病程10个月～12年；对照组40例，男20例，女20例，年龄17～56岁，病程11个月～12年。全部患者治疗前后均行裸眼视力、矫正视力、视野、常规眼前节裂隙灯以及眼底检查。对各类炎症、中央动脉栓塞、颅内肿瘤、外伤等原发病得到治疗控制后或趋于稳定的基础上，两组病例一般资料经统计学处理无显著性差异(P＞0.05)，具有可比性。
2、诊断标准(1)脊髓痨、颅内肿瘤、球后视神经炎及外伤史。(2)视力明显下降或失明。(3)视乳头边界清晰、苍白色、生理凹陷扩大、筛板孔清晰可见，血管变细。(4)视野向心性缩小。(5)继发性视神经萎缩为视神经炎及水肿所致，乳头边界模糊，筛板孔不清，视网膜可见色素沉着，血管变细。(6)眼底血管荧光造影不见荧光显影。具备1～5项即可诊断。
肝肾不足型症候：眼无外证，视力渐降，甚至失明；眼底检查：视乳头色淡或苍白，视网膜血管细。头昏耳鸣，腰膝酸软，脉细无力。
3、治疗及护理方法治疗组服用本发明所述中药制剂，称取夏枯草13g、密蒙花9g、茱苓草11g、满天星15g、蜜柑草30g、枸杞子13g、楮实11g、野大豆藤55g、龙船花18g、凤尾七9g、狗尾巴参15g、向阳花14g，每日1剂，日煎2次，分早、晚两次服用，3周为一疗程；对照组予维生素B110mg，每日3次口服；维生素B1100mg、维生素B12100μg，每日1次肌肉注射；2周为一疗程，两组均连续治疗4个疗程。
4、疗效标准痊愈：视力恢复到1.0以上，视野中心暗点消失；显效：视力提高4行以上，视野中心暗点缩小或绝对暗点变为相对暗点；好转：视力提高两行以上，视野无变化；无效：视力和视野与治疗前相同或有退步。
5、治疗结果患者治疗4个疗程后观察疗效，治疗组40例，其中痊愈15例(37.5％)，显效15例(37.5％)，好转6例(15％)，无效4例(10％)，总有效率90％。对照组40例，其中痊愈8例(20％)，显效10例(25％)，好转10例(25％)，无效12例(30％)，总有效率70％。两组总有效率比较差异有显著性意义(P＜0.05)，治疗组治疗效果明显优于对照组。
具体实施方式
实施方式一：称取夏枯草10g、密蒙花6g、茱苓草9g、满天星12g、蜜柑草25g、枸杞子10g、楮实8g、野大豆藤50g、龙船花14g、凤尾七7g、狗尾巴参12g、向阳花12g，按传统方法制成汤剂。
实施方式二：称取夏枯草13g、密蒙花9g、茱苓草11g、满天星15g、蜜柑草30g、枸杞子13g、楮实11g、野大豆藤55g、龙船花18g、凤尾七9g、狗尾巴参15g、向阳花14g，按传统方法制成汤剂。
实施方式三：称取夏枯草16g、密蒙花12g、茱苓草14g、满天星18g、蜜柑草35g、枸杞子16g、楮实14g、野大豆藤60g、龙船花20g、凤尾七11g、狗尾巴参18g、向阳花16g，按传统方法制成汤剂。

Claims (2)

1.一种治疗肝肾阴虚型视神经萎缩的中药制剂，其特征在于该中药制剂由以下重量份的中药制成：夏枯草10-16份、密蒙花6-12份、茱苓草9-14份、满天星12-18份、蜜柑草25-35份、枸杞子10-16份、楮实8-14份、野大豆藤50-60份、龙船花14-20份、凤尾七7-11份、狗尾巴参12-18份、向阳花12-16份。
2.如权利要求1所述的一种治疗肝肾阴虚型视神经萎缩的中药制剂，其特征在于该中药制剂由以下重量份的中药制成：优选的：夏枯草13份、密蒙花9份、茱苓草11份、满天星15份、蜜柑草30份、枸杞子13份、楮实11份、野大豆藤55份、龙船花18份、凤尾七9份、狗尾巴参15份、向阳花14份。
CN201510973577.5A 2015-12-14 2015-12-14 一种治疗肝肾阴虚型视神经萎缩的中药制剂 Pending CN105582257A (zh)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108126107A (zh) * 2017-10-25 2018-06-08 杨小丽 一种治疗青盲的药物及其制备方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104069364A (zh) * 2013-03-26 2014-10-01 李金保 一种治疗视神经萎缩的中药
CN104306546A (zh) * 2014-08-15 2015-01-28 河南科技大学 一种用于治疗视神经萎缩的中药组合物及其汤剂、丸剂和散剂
CN104435803A (zh) * 2014-10-28 2015-03-25 王春磊 一种治疗肝肾不足型视神经萎缩的中药制剂
CN104873668A (zh) * 2015-06-12 2015-09-02 孙胜波 一种治疗视神经萎缩的中药组合物

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104069364A (zh) * 2013-03-26 2014-10-01 李金保 一种治疗视神经萎缩的中药
CN104306546A (zh) * 2014-08-15 2015-01-28 河南科技大学 一种用于治疗视神经萎缩的中药组合物及其汤剂、丸剂和散剂
CN104435803A (zh) * 2014-10-28 2015-03-25 王春磊 一种治疗肝肾不足型视神经萎缩的中药制剂
CN104873668A (zh) * 2015-06-12 2015-09-02 孙胜波 一种治疗视神经萎缩的中药组合物

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
刘莉: "针药配合治疗视神经萎缩", 《河南中医》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108126107A (zh) * 2017-10-25 2018-06-08 杨小丽 一种治疗青盲的药物及其制备方法

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