CN105561181A - Chinese patent medicine for treating facial paralysis, and preparation method thereof - Google Patents
Chinese patent medicine for treating facial paralysis, and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a Chinese patent medicine for treating facial paralysis. The Chinese patent medicine is prepared from, by weight, 8-17 parts of Radix Berberidis, 8-19 parts of Callicarpa macrophylla, 7-16 parts of root of Physochlaina infundibularis Kuang, 8-16 parts of Radix Curcumae Aromaticae, 8-17 parts of ginseng, 9-18 parts of Adina rubella Hance, 7-18 parts of Ganoderma Lucidum, 8-18 parts of Chinese yam, 6-17 parts of Radix Astragali, 6-15 parts of Herba Cynomorii, 7-16 parts of panax notoginseng, 8-19 parts of hawthorn fruit, 5-12 parts of Pothos repens (Lour.)Merr, 4-12 parts of Poria cocos and 5-12 parts of hawthorn fruit. The Chinese patent medicine can promote facial neuritis treatment through invigorating blood circulation, relaxing veins, dredging meridians, regulating tendons, tonifying qi and tonifying, and clinic practices prove that the Chinese patent medicine has very a good curative effect.
Description
Technical field
The present invention relates to a kind of Chinese patent medicine for facial paralysis and preparation method thereof, belong to tcm field.
Background technology
Facial neuritis, is commonly called as " facial paralysis ", is a kind of commonly encountered diseases that is principal character with facial expression muscle group dyskinesia.General symptom is facial hemiparalysis.It is a kind of commonly encountered diseases, frequently-occurring disease, and it is not by age limit.Patient is often the most basic to lift the actions such as eyebrow, eye closing, drum mouth and all cannot complete.Most of patients often in early morning wash one's face, gargle time catch sight of that side buccal action is ineffective, face is crooked.The complete paralytic of sick side surface part histrionic muscles, forehead line disappears, palpebral fissure expands, nasolabial fold is smooth, ptosis of labial angle.The actions such as sick side can not make wrinkle volume, frown, close order, air-blowing and be in a pout.The drum cheek, with when whistling, leaks gas because Ipsilateral lip can not close.During feed, food debris is often stranded in the tooth buccal space of disease side, and often has saliva to drop down from this side.Because lacrimal point is with lower eyelid ectropion, make tear can not be excessive by normal drainage.Wherein peripheral facial paralysis sickness rate is very high, and the most common person is facial neuritis or Bell's palsy.Some patients can have 2/3 dysgeusia before tongue, external auditory meatus herpes etc.Doctor trained in Western medicine thinks that to cause the prosopoplegic cause of disease to have multiple, is divided into maincenter profile neural paralysis and peripheral profiles neural paralysis two kinds clinically.Commonly encountered diseases because: 1. infection, many being activated by the varicella zoster virus of resting state in nervus facialis sensory ganglion of hiding of infection causes; 2. ear source property disease, 3. autoimmune response; 4. tumor; 5. neurogenic; 6. traumatic; 7. poisoning, as alcoholism, Long Term Contact Toxic; 8. dysbolismus, as diabetes, vitamin deficiency; 9. vascular function is incomplete; 10. congenital nuclear agenesis.The traditional Chinese medical science thinks that its cause of disease is many because of positive QI-insufficiency, and venation is hollow, affection of exogenous wind-cold, the heresy of wind heat, invade sun bright, the arteries and veins of few sun, so that lose through gas obstruction of meridian foster, muscle amyotonia is not received and falls ill, facial paralysis is because wind-phlegm hinders in women's head-ornaments meridians, the arteries and veins jaws ring lip that foot sun is bright, and the arteries and veins of the sufficient sun arises from inner canthus, it is turbid that Yang Mingnei stores expectorant, in wind during the sun is outer, wind-phlegm hinders in women's head-ornaments meridians, then unfavorable through then, muscles loses supports, need not and delay, naivete part QI and blood still can be run, relatively anxious, slow person is anxious person traction, therefore facial hemiparalysis.Doctor trained in Western medicine generally adopts operation to carry out the treatment of facial neuritis, and treatment cost is high, and the course for the treatment of is loaded down with trivial details.The traditional Chinese medical science adopts acupuncture and moxibustion therapy to have certain effect to facial paralysis, but it is not obvious to there is curative effect, the problem that effective percentage is low.
Summary of the invention
For prior art exist deficiency, technical problem to be solved by this invention is, provides a kind of Chinese patent medicine for facial paralysis and preparation method thereof, determined curative effect, comprehensively regulating, after treatment not easily recurrence and cheap, have no side effect, can long-term taking.
For solving the problems of the technologies described above, the technical scheme that the present invention takes is, for a Chinese patent medicine for facial paralysis, be made up of the raw material of following parts by weight: Radix Berberidis 8-17 part, Folium Callicarpae Macrophyllae 8-19 part, Radix Physochlainae 7-16 part, Radix Curcumae 8-16 part, Radix Ginseng 8-17 part, Fructus Adinae 9-18 part, Ganoderma lucidum seu Japonicum 7-18 part, Rhizoma Dioscoreae 8-18 part, Radix Astragali 6-17 part, Herba Cynomorii 6-15 part, Radix Notoginseng 7-16 part, crataegus pin natifida var. Major 8-19 part, Caulis et Folium Pothi Repentis 5-12 part, Poria 4-12 part, crataegus pin natifida var. Major 5-12 part.
Optimize, the above-mentioned Chinese patent medicine for facial paralysis, is made up of the raw material of following parts by weight: Radix Berberidis 10-15 part, Folium Callicarpae Macrophyllae 10-15 part, Radix Physochlainae 8-12 part, Radix Curcumae 10-14 part, Radix Ginseng 10-14 part, Fructus Adinae 12-14 part, Ganoderma lucidum seu Japonicum 10-14 part, Rhizoma Dioscoreae 9-14 part, Radix Astragali 7-10 part, Herba Cynomorii 8-12 part, Radix Notoginseng 8-11 part, crataegus pin natifida var. Major 10-14 part Caulis et Folium Pothi Repentis 6-9 part, Poria 6-8 part, crataegus pin natifida var. Major 8-10 part.
Optimize, the above-mentioned Chinese patent medicine for facial paralysis, is made up of the raw material of following parts by weight: Radix Berberidis 12 parts, Folium Callicarpae Macrophyllae 12 parts, Radix Physochlainae 11 parts, Radix Curcumae 12 parts, Radix Ginseng 11 parts, Fructus Adinae 13 parts, Ganoderma lucidum seu Japonicum 12 parts, Rhizoma Dioscoreae 12 parts, the Radix Astragali 8 parts, Herba Cynomorii 10 parts, Radix Notoginseng 10 parts, crataegus pin natifida var. Major 11 parts, Caulis et Folium Pothi Repentis 8 parts, 7 parts, Poria, crataegus pin natifida var. Major 9 parts.
For a manufacture method for the Chinese patent medicine of facial paralysis, be made up of following steps:
(1) by Radix Berberidis, Radix Curcumae, Radix Ginseng, Fructus Adinae, Ganoderma lucidum seu Japonicum and Rhizoma Dioscoreae grind into powder, stir;
(2) Folium Callicarpae Macrophyllae, Radix Physochlainae, the Radix Astragali, Herba Cynomorii, Radix Notoginseng, crataegus pin natifida var. Major, Caulis et Folium Pothi Repentis, Poria, crataegus pin natifida var. Major are put into yellow wine, add heat soaking 64-88 hour, heating-up temperature is 75 degrees Celsius;
(3) mixed-powder getting step (1) puts into distilled water, soaks 45-60 hour;
(4) heated by the solution that step (3) completes, heating-up temperature is 68 degrees Celsius, and heat time heating time is 80 hours;
(5) by the mixed solution centrifugal filtration of step (4), the medicine juice after filtering is filtered and reclaims, by medicinal residues filtering;
(6) medicine juice that step (5) and step (2) complete is uniformly mixed post-heating to 95 degree Celsius, is heated to the viscosity of medicine juice to 2.5-3.6;
(7) medicine juice that step (6) completes is carried out pasteurize, the medicine juice after sterilization is loaded sealing bag evacuation and seals up for safekeeping.
Drug use result of the present invention shows there is following advantage: the present invention proposes employing and comprise multiple effective Chinese patent medicine new compositions and produce more favorably effect with synergism.The present invention, by promoting blood circulation to remove obstruction in the collateral, thin regulating menstruation muscle, QI invigorating tonification, promotes the recovery of facial neuritis, by clinical practice, has good curative effect.
Detailed description of the invention
embodiment 1
The present invention is a kind of Chinese patent medicine for facial paralysis, is made up of the raw material of following parts by weight: Radix Berberidis 8 parts, Folium Callicarpae Macrophyllae 8 parts, Radix Physochlainae 7 parts, Radix Curcumae 8 parts, Radix Ginseng 8 parts, Fructus Adinae 9 parts, Ganoderma lucidum seu Japonicum 7 parts, Rhizoma Dioscoreae 8 parts, the Radix Astragali 6 parts, Herba Cynomorii 6 parts, Radix Notoginseng 7 parts, crataegus pin natifida var. Major 8 parts, Caulis et Folium Pothi Repentis 5 parts, 4 parts, Poria, crataegus pin natifida var. Major 5 parts.
For a manufacture method for the Chinese patent medicine of facial paralysis, be made up of following steps:
(1) by Radix Berberidis, Radix Curcumae, Radix Ginseng, Fructus Adinae, Ganoderma lucidum seu Japonicum and Rhizoma Dioscoreae grind into powder, stir;
(2) Folium Callicarpae Macrophyllae, Radix Physochlainae, the Radix Astragali, Herba Cynomorii, Radix Notoginseng, crataegus pin natifida var. Major, Caulis et Folium Pothi Repentis, Poria, crataegus pin natifida var. Major are put into yellow wine, add heat soaking 72 hours, heating-up temperature is 75 degrees Celsius;
(3) mixed-powder getting step (1) puts into distilled water, soaks 52 hours;
(4) heated by the solution that step (3) completes, heating-up temperature is 68 degrees Celsius, and heat time heating time is 80 hours;
(5) by the mixed solution centrifugal filtration of step (4), the medicine juice after filtering is filtered and reclaims, by medicinal residues filtering;
(6) medicine juice that step (5) and step (2) complete is uniformly mixed post-heating to 95 degree Celsius, is heated to the viscosity to 2.9 of medicine juice;
(7) medicine juice that step (6) completes is carried out pasteurize, the medicine juice after sterilization is loaded sealing bag evacuation and seals up for safekeeping.
Medicine of the present invention is Chinese patent medicine decoction, sustained drug can be made to absorb, lasting medicine, and drug absorption is complete, comparatively fast plays curative effect.
Efficacy assessment standard: facial neuritis curative effect determinate standard is formulated according to the curative effect determinate standard in " new Chinese medicine guideline of clinical investigations " [1] it " new Chinese medicine treatment facial neuritis guideline of clinical investigations ".Clinical cure: treat neuritis's transference cure below, and observation is not recurred in January again; Effective: after treatment, integration reduces more than 50%; Effective: after treatment, integration reduces 21% ~ 50%; Invalid: after treatment, integration reduces less than 20%; Onset time: it is onset time that integration reduces by 2 timesharing.3.2 therapeutic outcomes: treatment group 56 example, clinical cure 39 example (69.64%), effective 12 examples (21.43%), effective 2 examples, invalid 3 examples, total effective rate 94.64%, cure in 39 examples and recur 4 examples in 3 months, recurrence rate after healing 10.26%, has no adverse reaction in therapeutic process; Matched group 50 example, clinical cure 12 example (24%), effective 14 examples (28%), effective 14 examples, invalid 10 examples, total effective rate 80%, cures in 12 examples and recurs 7 examples in 3 months, recurrence rate after healing 58.33%.Analyze through statistics Ridit, two groups of cure rates, total effective rates compare, and difference has significant (P<0.01), and treatment group curative effect is obviously better than matched group.Clinical application onset time, in effective 53 examples for the treatment of group, the shortest 1 day, the longest 6 days, average 2.24 ± 0.87 days; In effective 40 examples of matched group, the shortest 2 days, the longest 36 days, average 5.84 ± 2.13 days.Treatment group onset time is significantly shorter than matched group, two groups onset time difference have significance (P<0.01).And treatment group medical expense, recurrence rate after healing are obviously less than matched group.
embodiment 2
The present invention is a kind of Chinese patent medicine for facial paralysis, is made up of the raw material of following parts by weight: Radix Berberidis 17 parts, Folium Callicarpae Macrophyllae 19 parts, Radix Physochlainae 16 parts, Radix Curcumae 16 parts, Radix Ginseng 17 parts, Fructus Adinae 18 parts, Ganoderma lucidum seu Japonicum 18 parts, Rhizoma Dioscoreae 18 parts, the Radix Astragali 17 parts, Herba Cynomorii 15 parts, Radix Notoginseng 16 parts, crataegus pin natifida var. Major 19 parts, Caulis et Folium Pothi Repentis 12 parts, 12 parts, Poria, crataegus pin natifida var. Major 12 parts.
For a manufacture method for the Chinese patent medicine of facial paralysis, be made up of following steps:
(1) by Radix Berberidis, Radix Curcumae, Radix Ginseng, Fructus Adinae, Ganoderma lucidum seu Japonicum and Rhizoma Dioscoreae grind into powder, stir;
(2) Folium Callicarpae Macrophyllae, Radix Physochlainae, the Radix Astragali, Herba Cynomorii, Radix Notoginseng, crataegus pin natifida var. Major, Caulis et Folium Pothi Repentis, Poria, crataegus pin natifida var. Major are put into yellow wine, add heat soaking 64 hours, heating-up temperature is 75 degrees Celsius;
(3) mixed-powder getting step (1) puts into distilled water, soaks 45 hours;
(4) heated by the solution that step (3) completes, heating-up temperature is 68 degrees Celsius, and heat time heating time is 80 hours;
(5) by the mixed solution centrifugal filtration of step (4), the medicine juice after filtering is filtered and reclaims, by medicinal residues filtering;
(6) medicine juice that step (5) and step (2) complete is uniformly mixed post-heating to 95 degree Celsius, is heated to the viscosity to 2.5 of medicine juice;
(7) medicine juice that step (6) completes is carried out pasteurize, the medicine juice after sterilization is loaded sealing bag evacuation and seals up for safekeeping.
embodiment 3
The present invention is a kind of Chinese patent medicine for facial paralysis, is made up of the raw material of following parts by weight: Radix Berberidis 12 parts, Folium Callicarpae Macrophyllae 12 parts, Radix Physochlainae 11 parts, Radix Curcumae 12 parts, Radix Ginseng 11 parts, Fructus Adinae 13 parts, Ganoderma lucidum seu Japonicum 12 parts, Rhizoma Dioscoreae 12 parts, the Radix Astragali 8 parts, Herba Cynomorii 10 parts, Radix Notoginseng 10 parts, crataegus pin natifida var. Major 11 parts, Caulis et Folium Pothi Repentis 8 parts, 7 parts, Poria, crataegus pin natifida var. Major 9 parts.
For a manufacture method for the Chinese patent medicine of facial paralysis, be made up of following steps:
(1) by Radix Berberidis, Radix Curcumae, Radix Ginseng, Fructus Adinae, Ganoderma lucidum seu Japonicum and Rhizoma Dioscoreae grind into powder, stir;
(2) Folium Callicarpae Macrophyllae, Radix Physochlainae, the Radix Astragali, Herba Cynomorii, Radix Notoginseng, crataegus pin natifida var. Major, Caulis et Folium Pothi Repentis, Poria, crataegus pin natifida var. Major are put into yellow wine, add heat soaking 88 hours, heating-up temperature is 75 degrees Celsius;
(3) mixed-powder getting step (1) puts into distilled water, soaks 60 hours;
(4) heated by the solution that step (3) completes, heating-up temperature is 68 degrees Celsius, and heat time heating time is 80 hours;
(5) by the mixed solution centrifugal filtration of step (4), the medicine juice after filtering is filtered and reclaims, by medicinal residues filtering;
(6) medicine juice that step (5) and step (2) complete is uniformly mixed post-heating to 95 degree Celsius, is heated to the viscosity to 3.6 of medicine juice;
(7) medicine juice that step (6) completes is carried out pasteurize, the medicine juice after sterilization is loaded sealing bag evacuation and seals up for safekeeping.
Certainly, above-mentioned explanation is not limitation of the present invention, and the present invention is also not limited to above-mentioned citing; those skilled in the art; in essential scope of the present invention, the change made, remodeling, interpolation or replacement, all should belong to protection scope of the present invention.
Claims (4)
1. for a Chinese patent medicine for facial paralysis, it is characterized in that: be made up of the raw material of following parts by weight: Radix Berberidis 8-17 part, Folium Callicarpae Macrophyllae 8-19 part, Radix Physochlainae 7-16 part, Radix Curcumae 8-16 part, Radix Ginseng 8-17 part, Fructus Adinae 9-18 part, Ganoderma lucidum seu Japonicum 7-18 part, Rhizoma Dioscoreae 8-18 part, Radix Astragali 6-17 part, Herba Cynomorii 6-15 part, Radix Notoginseng 7-16 part, crataegus pin natifida var. Major 8-19 part, Caulis et Folium Pothi Repentis 5-12 part, Poria 4-12 part, crataegus pin natifida var. Major 5-12 part.
2. the Chinese patent medicine for facial paralysis according to claim 1, is characterized in that: be made up of the raw material of following parts by weight: Radix Berberidis 10-15 part, Folium Callicarpae Macrophyllae 10-15 part, Radix Physochlainae 8-12 part, Radix Curcumae 10-14 part, Radix Ginseng 10-14 part, Fructus Adinae 12-14 part, Ganoderma lucidum seu Japonicum 10-14 part, Rhizoma Dioscoreae 9-14 part, Radix Astragali 7-10 part, Herba Cynomorii 8-12 part, Radix Notoginseng 8-11 part, crataegus pin natifida var. Major 10-14 part, Caulis et Folium Pothi Repentis 6-9 part, Poria 6-8 part, crataegus pin natifida var. Major 8-10 part.
3. the Chinese patent medicine for facial paralysis according to claim 1, is characterized in that: be made up of the raw material of following parts by weight: Radix Berberidis 12 parts, Folium Callicarpae Macrophyllae 12 parts, Radix Physochlainae 11 parts, Radix Curcumae 12 parts, Radix Ginseng 11 parts, Fructus Adinae 13 parts, Ganoderma lucidum seu Japonicum 12 parts, Rhizoma Dioscoreae 12 parts, the Radix Astragali 8 parts, Herba Cynomorii 10 parts, Radix Notoginseng 10 parts, crataegus pin natifida var. Major 11 parts, Caulis et Folium Pothi Repentis 8 parts, 7 parts, Poria, crataegus pin natifida var. Major 9 parts.
4. the manufacture method of the Chinese patent medicine for facial paralysis of any one in claim 1-3, it is made up of following steps:
(1) by Radix Berberidis, Radix Curcumae, Radix Ginseng, Fructus Adinae, Ganoderma lucidum seu Japonicum and Rhizoma Dioscoreae grind into powder, stir;
(2) Folium Callicarpae Macrophyllae, Radix Physochlainae, the Radix Astragali, Herba Cynomorii, Radix Notoginseng, crataegus pin natifida var. Major, Caulis et Folium Pothi Repentis, Poria, crataegus pin natifida var. Major are put into yellow wine, add heat soaking 64-88 hour, heating-up temperature is 75 degrees Celsius;
(3) mixed-powder getting step (1) puts into distilled water, soaks 45-60 hour;
(4) heated by the solution that step (3) completes, heating-up temperature is 68 degrees Celsius, and heat time heating time is 80 hours;
(5) by the mixed solution centrifugal filtration of step (4), the medicine juice after filtering is filtered and reclaims, by medicinal residues filtering;
(6) medicine juice that step (5) and step (2) complete is uniformly mixed post-heating to 95 degree Celsius, is heated to the viscosity of medicine juice to 2.5-3.6;
(7) medicine juice that step (6) completes is carried out pasteurize, the medicine juice after sterilization is loaded sealing bag evacuation and seals up for safekeeping.
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