CN105548563B - mimecan在评价心力衰竭中的用途 - Google Patents
mimecan在评价心力衰竭中的用途 Download PDFInfo
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- CN105548563B CN105548563B CN201510995316.3A CN201510995316A CN105548563B CN 105548563 B CN105548563 B CN 105548563B CN 201510995316 A CN201510995316 A CN 201510995316A CN 105548563 B CN105548563 B CN 105548563B
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- Prior art keywords
- mimecan
- heart failure
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- sample
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6806—Determination of free amino acids
- G01N33/6812—Assays for specific amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4703—Regulators; Modulating activity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/325—Heart failure or cardiac arrest, e.g. cardiomyopathy, congestive heart failure
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Biophysics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
Description
Claims (5)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP09009666 | 2009-07-27 | ||
EP09009666.0 | 2009-07-27 | ||
CN2010800291365A CN102549436A (zh) | 2009-07-27 | 2010-07-23 | mimecan在评价心力衰竭中的用途 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2010800291365A Division CN102549436A (zh) | 2009-07-27 | 2010-07-23 | mimecan在评价心力衰竭中的用途 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN105548563A CN105548563A (zh) | 2016-05-04 |
CN105548563B true CN105548563B (zh) | 2017-09-22 |
Family
ID=41320068
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2010800291365A Pending CN102549436A (zh) | 2009-07-27 | 2010-07-23 | mimecan在评价心力衰竭中的用途 |
CN201510995316.3A Active CN105548563B (zh) | 2009-07-27 | 2010-07-23 | mimecan在评价心力衰竭中的用途 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2010800291365A Pending CN102549436A (zh) | 2009-07-27 | 2010-07-23 | mimecan在评价心力衰竭中的用途 |
Country Status (8)
Country | Link |
---|---|
US (1) | US10234462B2 (zh) |
EP (1) | EP2460015B1 (zh) |
JP (1) | JP5592487B2 (zh) |
CN (2) | CN102549436A (zh) |
CA (1) | CA2769243C (zh) |
ES (1) | ES2512018T3 (zh) |
HK (1) | HK1224375A1 (zh) |
WO (1) | WO2011012268A1 (zh) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2671298C (en) * | 2007-01-25 | 2020-07-28 | F. Hoffmann-La Roche Ag | Use of igfbp-7 in the assessment of heart failure |
BR122021026652B1 (pt) | 2011-10-17 | 2022-08-23 | F. Hoffmann-La Roche Ag | Método in vitro para diagnosticar fibrilação atrial intermitente, uso de uma troponina cardíaca e dispositivo para diagnosticar fibrilação atrial intermitente |
ES2913539T3 (es) | 2012-09-12 | 2022-06-02 | Hoffmann La Roche | Identificación de pacientes con fracción de acortamiento anómala |
WO2014086833A1 (en) | 2012-12-04 | 2014-06-12 | Roche Diagnostics Gmbh | Biomarkers in the selection of therapy of heart failure |
ES2712201T3 (es) | 2014-01-28 | 2019-05-09 | Hoffmann La Roche | Biomarcadores para la evaluación de riesgos y la monitorización del tratamiento en pacientes de insuficiencia cardíaca que han recibido terapia guiada por el péptido natriurético de tipo B |
ES2676553T3 (es) | 2014-03-26 | 2018-07-20 | F. Hoffmann-La Roche Ag | IGFBP7 para el diagnóstico de la disfunción diastólica |
US11011274B2 (en) * | 2016-03-09 | 2021-05-18 | Conduent Business Services, Llc | Method and apparatus for predicting mortality of a patient using trained classifiers |
CN110018309B (zh) * | 2018-01-08 | 2023-07-04 | 成都市第三人民医院 | 通过蛋白标志物判断结直肠癌预后的试剂盒 |
US11446009B2 (en) | 2018-12-11 | 2022-09-20 | Eko.Ai Pte. Ltd. | Clinical workflow to diagnose heart disease based on cardiac biomarker measurements and AI recognition of 2D and doppler modality echocardiogram images |
US11931207B2 (en) | 2018-12-11 | 2024-03-19 | Eko.Ai Pte. Ltd. | Artificial intelligence (AI) recognition of echocardiogram images to enhance a mobile ultrasound device |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1951967A (zh) * | 2005-10-21 | 2007-04-25 | 上海第二医科大学附属瑞金医院 | 抗人骨生成诱导因子单克隆抗体及其制备和用途 |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6333397B1 (en) | 1989-04-25 | 2001-12-25 | Roche Diagnostics Gmbh | Monoclonal antibodies to troponin T and their production |
DE3922873A1 (de) | 1989-04-25 | 1990-10-31 | Boehringer Mannheim Gmbh | Spezifische antikoerper gegen troponin t, ihre herstellung und verwendung in einem reagenz zur bestimmung von hermuskelnekrosen |
US5807522A (en) | 1994-06-17 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for fabricating microarrays of biological samples |
DE69633780T3 (de) | 1995-04-18 | 2011-05-05 | Biosite Incorporated, San Diego | Verfahren zum assay von troponin i und t und komplexen von troponin i und t und auswahl von antikörpern zur verwendung in immunoassays |
WO2000045176A2 (de) | 1999-01-29 | 2000-08-03 | Roche Diagnostics Gmbh | VERFAHREN ZUM NACHWEIS VON N-TERMINALEM proBNP |
JP2003511012A (ja) * | 1999-09-24 | 2003-03-25 | ヒューマン ジノーム サイエンシーズ, インコーポレイテッド | 32個のヒト分泌タンパク質 |
AUPR005600A0 (en) * | 2000-09-12 | 2000-10-05 | University Of Sydney, The | Diagnostic assay |
US7713705B2 (en) * | 2002-12-24 | 2010-05-11 | Biosite, Inc. | Markers for differential diagnosis and methods of use thereof |
US6461828B1 (en) * | 2001-09-04 | 2002-10-08 | Syn X Pharma | Conjunctive analysis of biological marker expression for diagnosing organ failure |
PL1625163T3 (pl) | 2003-05-12 | 2012-01-31 | Hoffmann La Roche | Sposoby wykrywania proBMP przeciwciałem monoklonalnym wiążącym się z aminokwasami 38-43 |
PT1638591E (pt) | 2003-05-29 | 2013-05-22 | Univ Manchester | Agonistas de slrp de classe iii para a redução da formação de vasos sanguíneos |
US20080090759A1 (en) * | 2004-08-30 | 2008-04-17 | Robert Kokenyesi | Methods and kits for predicting risk for preterm labor |
US20080254479A1 (en) | 2004-08-30 | 2008-10-16 | Cervimark, Llc | Methods and Kits For Predicting Risk For Preterm Labor |
GB0423273D0 (en) | 2004-10-20 | 2004-11-24 | Univ Manchester | Treatment of cancer |
US20060246484A1 (en) | 2005-03-10 | 2006-11-02 | Hare Joshua M | Identification of gene expression by heart failure etiology |
EP1929295A4 (en) * | 2005-08-30 | 2010-03-17 | Biosite Inc | USE OF SOLUBLE FLT-1 AND ITS FRAGMENTS IN CARDIOVASCULAR CONDITIONS |
ES2344993T3 (es) * | 2006-03-24 | 2010-09-13 | F. Hoffmann-La Roche Ag | Medios y metodos para la diferenciacion de la necrosis de miocardio aguda y cronica en pacientes sintomaticos. |
CA2671298C (en) * | 2007-01-25 | 2020-07-28 | F. Hoffmann-La Roche Ag | Use of igfbp-7 in the assessment of heart failure |
DE102007010834A1 (de) | 2007-03-03 | 2008-09-04 | Brahms Aktiengesellschaft | Diagnose und Risikostratifizierung von Herzinsuffizienz für NYHA I Patienten |
DE602007004570D1 (de) * | 2007-03-06 | 2010-03-18 | Roche Diagnostics Gmbh | Verwendung von Nogo-C bei der Beurteilung von Herzversagen |
EP1995596B1 (en) | 2007-05-24 | 2011-12-14 | F. Hoffmann-La Roche AG | Methods for assessing heart failure in patients with atrial fibrillation using GDF-15 |
EP2210111A1 (en) * | 2007-10-10 | 2010-07-28 | Roche Diagnostics GmbH | Natriuretic peptide/troponin ratio for the assessment of preexisting myocardial dysfunction in patients with acute coronary syndrome |
US8617877B2 (en) * | 2007-11-02 | 2013-12-31 | The Johns Hopkins University | Cardiac stem cell and myocyte secreted paracrine factors |
-
2010
- 2010-07-23 JP JP2012522011A patent/JP5592487B2/ja active Active
- 2010-07-23 CA CA2769243A patent/CA2769243C/en active Active
- 2010-07-23 CN CN2010800291365A patent/CN102549436A/zh active Pending
- 2010-07-23 ES ES10740528.4T patent/ES2512018T3/es active Active
- 2010-07-23 WO PCT/EP2010/004521 patent/WO2011012268A1/en active Application Filing
- 2010-07-23 EP EP10740528.4A patent/EP2460015B1/en active Active
- 2010-07-23 CN CN201510995316.3A patent/CN105548563B/zh active Active
-
2012
- 2012-01-26 US US13/359,276 patent/US10234462B2/en active Active
-
2016
- 2016-11-01 HK HK16112526.0A patent/HK1224375A1/zh unknown
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1951967A (zh) * | 2005-10-21 | 2007-04-25 | 上海第二医科大学附属瑞金医院 | 抗人骨生成诱导因子单克隆抗体及其制备和用途 |
Also Published As
Publication number | Publication date |
---|---|
CA2769243C (en) | 2017-08-22 |
WO2011012268A1 (en) | 2011-02-03 |
WO2011012268A8 (en) | 2011-06-30 |
HK1224375A1 (zh) | 2017-08-18 |
CN105548563A (zh) | 2016-05-04 |
US10234462B2 (en) | 2019-03-19 |
CN102549436A (zh) | 2012-07-04 |
ES2512018T3 (es) | 2014-10-23 |
EP2460015B1 (en) | 2014-08-20 |
JP2013500482A (ja) | 2013-01-07 |
CA2769243A1 (en) | 2011-02-03 |
US20120156703A1 (en) | 2012-06-21 |
JP5592487B2 (ja) | 2014-09-17 |
EP2460015A1 (en) | 2012-06-06 |
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