CN105535829A - 一种治疗慢性乙型肝炎的内服药物及其制备方法 - Google Patents
一种治疗慢性乙型肝炎的内服药物及其制备方法 Download PDFInfo
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Abstract
本发明属于中医药技术领域,目的是根据中医对慢性乙型肝炎的认识机理而提供的一种治疗慢性乙型肝炎的内服药物,所述药物的各个组分及其质量份比如下所示:半边莲、白花蛇舌草、茵陈、柴胡、吴茱萸、金钱草、郁金、香附、板蓝根、白芍、丹参、甘草、栀子;本发明提供的药物药效好、见效快,是一个标本兼治的中药组方,特别适合临床使用。
Description
技术领域
本发明涉及中医药技术领域,具体涉及一种治疗慢性乙型肝炎的内服药物,特别是供慢性乙型肝炎患者使用的内服药物及其制备方法的领域。
背景技术
中医学者认为:慢性乙型肝炎(简称乙肝)是指乙肝病毒检测为阳性,病程超过半年或发病日期不明确而临床有慢性肝炎表现者。其临床表现为乏力、畏食、恶心、腹胀、肝区疼痛等症状。肝大,质地为中等硬度,有轻压痛。病情重者可伴有慢性肝病面容、蜘蛛痣、肝掌、脾大,肝功能可异常或持续异常。根据临床表现分为轻度、中度和重度。而慢性乙肝携带是指乙肝病毒检测为阳性,无慢性肝炎症状,一年内连续随访3次以上血清ALT和AST均无异常,且肝组织学检查正常者。
那么,就如何找到一种可有效治疗慢性乙型肝炎的药物,是我们目前急需要解决的问题。
发明内容
改革开放以来,随着我国中医中药学的不断发展,在治疗慢性乙型肝炎上,人们渐渐意识到了中医治疗上述疾病的优点,且在治疗过程中无任何毒副作用和费用低廉等优势,针对现有西医治疗上述疾病的现状,本发明的目的是在于提供一种治疗慢性乙型肝炎的内服药物及其制备方法,以解决慢性乙型肝炎患者早日恢复健康的问题。该中药组合物是以常见的中药为原料,具有见效快、疗效显著等特点,并可有效治疗上述慢性乙型肝炎。
为达到上述发明的目的,本发明所采用的技术方案为:提供一种治疗慢性乙型肝炎的内服药物及其制备方法,其特征在于,所述药物的各个组分及其质量份比如下所示:
半边莲15-28g、白花蛇舌草15-25g、茵陈6-12g、柴胡4-13g、吴茱萸1.5-5g、金钱草20-25g、郁金3-16g、香附5-18g、板蓝根9-20g、白芍10-18g、丹参5-18g、甘草3-15g、栀子5-10g。
一种治疗慢性乙型肝炎的内服药物及其制备方法,其特征在于,所述药物的各个组分及其质量份比如下所示:
半边莲16-25g、白花蛇舌草16-22g、茵陈7-11g、柴胡5-12g、吴茱萸2-4g、金钱草20-23g、郁金4-15g、香附6-16g、板蓝根10-18g、白芍11-16g、丹参6-16g、甘草4-13g、栀子6-9g。
一种治疗慢性乙型肝炎的内服药物及其制备方法,其特征在于,所述“最佳方案”的中药物的各个组分及其质量份比如下所示:
半边莲21g、白花蛇舌草20g、茵陈10g、柴胡11g、吴茱萸3g、金钱草20g、郁金14g、香附15g、板蓝根16g、白芍15g、丹参15g、甘草12g、栀子8g。
一种治疗慢性乙型肝炎的内服药物及其制备方法,其特征在于,所述方法包括如下步骤制备而成:
A、将上述原料中药拣去杂质和粉尘后,按照质量份比分别粉碎成粗粒状包煎;
B、首先将上述包好的原料中药放入冷开水中浸泡半小时后,再将浸泡好的药物和浸泡药物的澄清液一并放入煎药机内,注入过药35mm的冷开水进行第一次煎煮40分钟,滤取药液后,再次注入过药32mm的微温开水进行第二次煎煮35分钟,两次混合浓缩成50%的中药液540毫升备用。
一种治疗慢性乙型肝炎的内服药物及其制备方法,其特征在于,所述服用方法为:将制备好的中药液以一天服用,每日一剂,早中晚各服一次,给药量180毫升/次,饭前服。服药90-210剂,诸症皆除,病获痊愈。
本发明中药组合物中的各原料中药在中国药典、中国辞典以及中华本草中均有详细的记载。本发明选用其中最常见的中药为原料,充分发挥各组分的药性:
半边莲,性味:味甘、性平,具有清热解毒;利水消肿之功能,用于治疗毒蛇咬伤、痈肿疔疮、扁桃体炎、温疹、足癣、跌打损伤、湿热黄疸、阑尾炎、肠炎、肾炎、肝硬化腹水及多种癌症;
白花蛇舌草,性味:味苦、甘、性温,无毒,具有清热解毒、利尿消肿、活血止痛之功能,用于治疗恶性肿瘤、阑尾炎、肝炎、支气管炎、扁桃体炎、喉炎、泌尿系统感染、盆腔炎、附件炎等症,外用治疮疖痈肿、毒蛇咬伤,现代中医临床用于治疗胃癌、食管癌、肠癌、子宫癌、鼻咽癌等多种癌症;
茵陈,性味:苦、辛、微寒,具有清湿热、退黄疸之功能,用于治疗黄疸尿少、湿疮瘙痒、传染性黄疸型肝炎;
柴胡,性味:苦、凉,具有和解表里、疏肝、升阳之功能,用于治疗寒热往来、胸满胁痛、口苦耳聋、头痛目眩、疟疾、下利脱肛、月经不调、子宫下垂等症;
吴茱萸,性味:辛、苦、热,有小毒,具有疏肝下气、温中散寒、燥湿助阳之功能,用于治疗劂阴头痛、胸腹胀满、呕吐吞酸、阳虚泄泻、吐泻转筋、寒疝脚气、外治口舌生疮;
金钱草,性味:微苦、性凉,具有利水通淋、清热解毒、散瘀消肿之功能,用于治疗肝胆及泌尿系结石、热淋;肾炎水肿、湿热黄疸、疮毒痈肿、毒蛇咬伤、跌打损伤;
郁金,性味:味辛、苦、性寒,具有活血止能、行气解郁、清心凉血、疏肝利胆之功效,用于治疗胸腹胁肋诸痛、妇女痛经、经闭、症瘕结块、热病神昏、癫狂、惊痫、吐血、衄备、血淋、砂淋、黄疸、胸腹胀痛、刺痛等症;
香附,性味:味辛、微寒,无毒,具有理气解郁、止痛调经之功能,用于治疗肝胃不和、气郁不舒、胸腹胁肋胀痛、痰饮痞满、月经不调、崩漏带下;
板蓝根,性味:苦、寒,具有清热解毒、凉血之功能,用于治疗温热发热、发斑、风热感冒、咽喉肿烂、流行性乙型脑炎、肝炎、腮腺炎;
白芍,性味:苦、酸、微寒,具有养血和营、缓急止痛、敛阴平肝之功能,用于治疗月经不调、经行腹痛、崩漏、自汗、盗汗、胁肋脘腹疼痛、四肢挛痛、头痛、眩晕等症;
丹参,性味:苦、微寒,具有活血调经、祛瘀止痛、凉血消痈、清心除烦、养血安神之功能,用于治疗月经不调、经闭痛经、症瘕积聚、胸腹刺痛、热痹疼痛、疮疡肿痛、心烦不眠、肝脾肿大、心绞痛等症;
甘草,性味:甘、平,具有补脾益气、清热解毒、祛痰止咳、缓急止痛、调和诸药之功能,用于治疗脾胃虚弱、倦怠乏力、心悸气短、咳嗽痰多、脘腹、四肢挛急疼痛、痈肿疮毒、缓解药物毒性、烈性等症;
栀子,性味:性寒、味苦,具有泻火除烦、清热利尿、凉血解毒之功能,用于治疗热病心烦、花疸尿赤、血淋涩痛、血热吐衄、目杰肿痛、火毒疮疡、扭伤。
本发明药物是基于中医治疗慢性乙型肝炎的辨病与辨证相结合的原则,从药理作用及作用机制认为:就慢性乙型肝炎一症,本发明所提供的中药组合物中的各原料中药药效共奏,对上述疾病有很好的治疗效果和调理作用。
具体实施方式
本发明就是针对上述慢性乙型肝炎的治疗而提出的一种中药配方,采用该配方制备的药物药效好,见效快、治疗周期短,是一个标本兼治的中药组方,特别适合临床使用。下面结合本发明的具体实施方式作进一步详细的描述:
实施例1:
一种治疗慢性乙型肝炎的内服药物及其制备方法,所述药物的各个组分及其质量份比如下所示:
半边莲21g、白花蛇舌草20g、茵陈10g、柴胡11g、吴茱萸3g、金钱草20g、郁金14g、香附15g、板蓝根16g、白芍15g、丹参15g、甘草12g、栀子8g。
实施例2:
一种治疗慢性乙型肝炎的内服药物及其制备方法,所述药物的各个组分及其质量份比如下所示:
半边莲25g、白花蛇舌草22g、茵陈11g、柴胡12g、吴茱萸4g、金钱草23g、郁金15g、香附16g、板蓝根18g、白芍16g、丹参16g、甘草13g、栀子9g。
实施例3:
一种治疗慢性乙型肝炎的内服药物及其制备方法,所述药物的各个组分及其质量份比如下所示:
半边莲28g、白花蛇舌草25g、茵陈12g、柴胡13g、吴茱萸5g、金钱草25g、郁金16g、香附18g、板蓝根20g、白芍18g、丹参18g、甘草15g、栀子10g。
典型病例:
经临床诊断治疗慢性乙型肝炎患者共160例,男性88例,女性72例,年龄为42岁以上的120例,只有40例为42岁以下。160例患者中痊愈的150例,显效8例,无效2例,总有效率达98%以上。经治疗后,症除而愈。
Claims (4)
1.一种治疗慢性乙型肝炎的内服药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
半边莲15-28g、白花蛇舌草15-25g、茵陈6-12g、柴胡4-13g、吴茱萸1.5-5g、金钱草20-25g、郁金3-16g、香附5-18g、板蓝根9-20g、白芍10-18g、丹参5-18g、甘草3-15g、栀子5-10g。
2.根据权利要求1所述的治疗慢性乙型肝炎的内服药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
半边莲16-25g、白花蛇舌草16-22g、茵陈7-11g、柴胡5-12g、吴茱萸2-4g、金钱草20-23g、郁金4-15g、香附6-16g、板蓝根10-18g、白芍11-16g、丹参6-16g、甘草4-13g、栀子6-9g。
3.根据权利要求1至2所述的治疗慢性乙型肝炎的内服药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
半边莲21g、白花蛇舌草20g、茵陈10g、柴胡11g、吴茱萸3g、金钱草20g、郁金14g、香附15g、板蓝根16g、白芍15g、丹参15g、甘草12g、栀子8g。
4.根据权利要求3所述的治疗慢性乙型肝炎的内服药物及其制备方法,其特征在于,所述方法包括如下步骤制备而成:
A、将上述原料中药拣去杂质和粉尘后,按照质量份比分别粉碎成粗粒状包煎;
B、首先将上述包好的原料中药放入冷开水中浸泡半小时后,再将浸泡好的药物和浸泡药物的澄清液一并放入煎药机内,注入过药35mm的冷开水进行第一次煎煮40分钟,滤取药液后,再次注入过药32mm的微温开水进行第二次煎煮35分钟,两次混合浓缩成50%的中药液540毫升备用。
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