CN105535605A - External sterilization antipyrotic cream and preparation method thereof - Google Patents

External sterilization antipyrotic cream and preparation method thereof Download PDF

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Publication number
CN105535605A
CN105535605A CN201610000845.XA CN201610000845A CN105535605A CN 105535605 A CN105535605 A CN 105535605A CN 201610000845 A CN201610000845 A CN 201610000845A CN 105535605 A CN105535605 A CN 105535605A
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parts
nano
mustard
powder
bactericidal antiphlogistic
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王孝存
吕志昊
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Shandong Hongtaiyang Environmental Protection Products Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/08Oxides; Hydroxides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Insects & Arthropods (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention relates to an external sterilization antipyrotic cream. The external sterilization antipyrotic cream is prepared from, by weight, 20-40 parts of negative ion powder, 10-20 parts of nano-silicon dioxide, 2-8 parts of nanometer magnesia, 1-5 parts of nanometer bamboo charcoal, 10-20 parts of moxa, 5-20 parts of honeysuckle, 5-15 parts of bamboo powder, 5-12 parts of mustard, 1-5 parts of borneol, 1-5 parts of Physalis alkekengi and 600-900 parts of distilled water. Due to the adopted pure plants, the external sterilization antipyrotic cream is free of side effects, has the effects of achieving sterilization, diminishing inflammation, clearing away heat and toxic materials, dispelling moisture and relieving itching, and particularly has the remarkable curative effect on inflammations caused by staphylococcus, escherichia coli and the like.

Description

A kind of external bactericidal antiphlogistic ointment and preparation method thereof
Technical field
The present invention relates to technical field of Chinese medicines, particularly a kind of external bactericidal antiphlogistic ointment and preparation method thereof.
Background technology
Acne is apt to occur in face and back, blocks that the bacteriological infection that causes and inflammation cause primarily of hypersteatosis, hair follicle, to the psychology of people with socially cause very large impact.Severe patient relies on Drug therapy, but containing a large amount of antibiotic and hormone in conventional medicine, life-time service can cause dependence and side effect.
For the dermatitis that the dermatosis of other classes causes as skin scald, burn, often see in daily life, as incorrect medication, skin histology can be made impaired, bring the burden on spiritual pressure and material to patient.
Summary of the invention
For solving the problem, the invention provides a kind of external bactericidal antiphlogistic ointment, external bactericidal antiphlogistic ointment of the present invention adopts pure natural medical, has no side effect, bactericidal anti-inflammatory effect is remarkable, and the inflammation especially caused staphylococcus and escherichia coli etc. has significant curative effect.
For achieving the above object, the present invention is achieved through the following technical solutions:
The present invention is formed by the preparation of raw material of following weight portion: anion powder 20-40 part, nano silicon 10-20 part, nano magnesia 2-8 part, bamboo charcoal nano 1-5 part, Folium Artemisiae Argyi 10-20 part, Flos Lonicerae 5-20 part, bamboo powder 5-15 part, mustard 5-12 part, Borneolum Syntheticum 1-5 part, Calyx Seu Fructus Physalis 1-5 part, distilled water 600-900 part.
The preferred technical solution of the present invention is: anion powder 30 parts, nano silicon 16 parts, nano magnesia 5 parts, bamboo charcoal nano 2 parts, Folium Artemisiae Argyi 13 parts, Flos Lonicerae 10 parts, bamboo powder 10 parts, 7 parts, mustard, Borneolum Syntheticum 3 parts, Calyx Seu Fructus Physalis 2 parts, distilled water 800 parts.
Prepare above-mentioned external bactericidal antiphlogistic ointment, comprise the following steps:
(1) raw material is got according to weight fraction another name;
(2) by Flos Lonicerae, mustard, Borneolum Syntheticum, Calyx Seu Fructus Physalis is pulverized for subsequent use;
(3) by Folium Artemisiae Argyi, Flos Lonicerae, bamboo powder, mustard, Borneolum Syntheticum, Calyx Seu Fructus Physalis puts into container, adds distilled water, at room temperature soaks after 2-3 hour, boils 1.5-3 hour, filter in time being down to room temperature with gauze, obtain filtrate and filtering residue under 100 C, for subsequent use;
(4) by anion powder, nano silicon, nano magnesia, bamboo charcoal nano joins in the filtering residue described in step (3), and after stirring, be 120 C in temperature, sterilize under the condition of 2 normal atmospheres 20min, obtains aseptic thick paste;
(5) filtrate described in step (3) is distilled under temperature is 100 C, obtain distillate, after to be distilled, in distillate, continue to pass into ozone 10min sterilize, obtain aseptic distillate;
(6) by the aseptic thick paste described in step (4) and the described aseptic distillate mixing of step (5), stir into paste, obtain external bactericidal antiphlogistic ointment of the present invention.
Described weight portion can be g, kg according to the needs of preparation, two, and the measurement units such as jin.Same measurement unit can only be used in same embodiment.
In external-applied ointment of the present invention, anion powder has higher activity, has very strong redox, can destroy the cell membrane of antibacterial or the activity of cellular plasm organized enzyme, reach the object of antibiotic and sterilizing.Meanwhile, anion powder can stimulate Cucumber Extract, reaches treatment comedo, the dermatosiss such as exedens dermatitis.
Nano silicon has physiological inertia, high adsorption, in the preparation of antibacterial, be commonly used for carrier, and when being used as carrier, adsorbable antibacterial ion, reaches the object of bactericidal antiphlogistic.
Nano magnesia has oxidisability and the Electrostatic Absorption to microorganism, utilizes these character can reach the object of bactericidal antiphlogistic.Nano magnesia especially has significant killing effect to escherichia coli, staphylococcus aureus and bacillus subtilis etc.
Summer-heat, antipyretic, removing toxic substances, can fall in Calyx Seu Fructus Physalis.
Folium Artemisiae Argyi, warming the meridian for stopping bleeding, antiinflammatory, antiallergic.
Flos Lonicerae, has heat-clearing and toxic substances removing, effect of antiinflammatory.Experiment in vitro shows, Flos Lonicerae as staphylococcus aureus, Hemolytic streptococcus, escherichia coli have significant inhibitory action, also has certain effect to other antibacterial such as tubercule bacillus to various pathogens.
Bamboo powder and mustard have the effect of heat-clearing and toxic substances removing.
Borneolum Syntheticum, have the loose poison of heat clearing away, effect of improving acuity of vision and removing nebula, can accelerate the elimination of inflammation, and promote stripping off of mucosa, the healing of ulcer, to the mucosal injury that antibacterial is caused, can play the effect of auxiliary treatment.
Bamboo charcoal nano, has very strong absorbability, has to antibacterial such as staphylococcus, escherichia coli, the Candida albicans of absorption the inhibitory action that well sterilizes.
Compared with prior art, the pure plant that the present invention adopts, have no side effect, have effect of bactericidal antiphlogistic, heat-clearing and toxic substances removing, removing dampness to relieve itching, the inflammation especially caused staphylococcus and escherichia coli etc. has significant curative effect.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described in further detail.
Embodiment 1: a kind of external bactericidal antiphlogistic ointment, formed by the preparation of raw material of following weight portion: anion powder 20 parts, nano silicon 10 parts, nano magnesia 2 parts, bamboo charcoal nano 1 part, Folium Artemisiae Argyi 10 parts, Flos Lonicerae 5 parts, bamboo powder 5 parts, 5 parts, mustard, Borneolum Syntheticum 1 part, Calyx Seu Fructus Physalis 1 part, distilled water 600 parts.
External bactericidal antiphlogistic ointment described in preparation, comprises the following steps:
(1) raw material is got according to weight fraction another name;
(2) by Flos Lonicerae, mustard, Borneolum Syntheticum, Calyx Seu Fructus Physalis is pulverized for subsequent use;
(3) by Folium Artemisiae Argyi, Flos Lonicerae, bamboo powder, mustard, Borneolum Syntheticum, Calyx Seu Fructus Physalis puts into container, adds distilled water, at room temperature soaks after 2-3 hour, boils 1.5-3 hour, filter in time being down to room temperature with gauze, obtain filtrate and filtering residue under 100 C, for subsequent use;
(4) by anion powder, nano silicon, nano magnesia, bamboo charcoal nano joins in the filtering residue described in step (3), and after stirring, be 120 C in temperature, sterilize under the condition of 2 normal atmospheres 20min, obtains aseptic thick paste;
(5) filtrate described in step (3) is distilled under temperature is 100 C, obtain distillate, after to be distilled, in distillate, continue to pass into ozone 10min sterilize, obtain aseptic distillate;
(6) by the aseptic thick paste described in step (4) and the described aseptic distillate mixing of step (5), stir into paste, obtain external bactericidal antiphlogistic ointment of the present invention.
Embodiment 2: a kind of external bactericidal antiphlogistic ointment, formed by the preparation of raw material of following weight portion: anion powder 25 parts, nano silicon 12 parts, nano magnesia 4 parts, bamboo charcoal nano 2 parts, Folium Artemisiae Argyi 12 parts, Flos Lonicerae 7 parts, bamboo powder 8 parts, 6 parts, mustard, Borneolum Syntheticum 2 parts, Calyx Seu Fructus Physalis 2 parts, distilled water 700 parts.
The present embodiment external bactericidal antiphlogistic ointment preparation method processing step and usage and dosage identical with embodiment 1.
Embodiment 3: a kind of external bactericidal antiphlogistic ointment, formed by the preparation of raw material of following weight portion: anion powder 30 parts, nano silicon 16 parts, nano magnesia 5 parts, bamboo charcoal nano 2 parts, Folium Artemisiae Argyi 13 parts, Flos Lonicerae 10 parts, bamboo powder 10 parts, 7 parts, mustard, Borneolum Syntheticum 3 parts, Calyx Seu Fructus Physalis 2 parts, distilled water 800 parts.
The present embodiment external bactericidal antiphlogistic ointment preparation method processing step and usage and dosage identical with embodiment 1.
Embodiment 4: a kind of external bactericidal antiphlogistic ointment, formed by the preparation of raw material of following weight portion: anion powder 33 parts, nano silicon 17 parts, nano magnesia 6 parts, bamboo charcoal nano 3 parts, Folium Artemisiae Argyi 15 parts, Flos Lonicerae 13 parts, bamboo powder 11 parts, 9 parts, mustard, Borneolum Syntheticum 3 parts, Calyx Seu Fructus Physalis 3 parts, distilled water 850 parts.
The present embodiment external bactericidal antiphlogistic ointment preparation method processing step and usage and dosage identical with embodiment 1.
Embodiment 5: a kind of external bactericidal antiphlogistic ointment, formed by the preparation of raw material of following weight portion: anion powder 35 parts, nano silicon 18 parts, nano magnesia 7 parts, bamboo charcoal nano 4 parts, Folium Artemisiae Argyi 16 parts, Flos Lonicerae 16 parts, bamboo powder 13 parts, 10 parts, mustard, Borneolum Syntheticum 4 parts, Calyx Seu Fructus Physalis 4 parts, distilled water 880 parts.
The present embodiment external bactericidal antiphlogistic ointment preparation method processing step and usage and dosage identical with embodiment 1.
Embodiment 6: a kind of external bactericidal antiphlogistic ointment, formed by the preparation of raw material of following weight portion: anion powder 40 parts, nano silicon 20 parts, nano magnesia 8 parts, bamboo charcoal nano 5 parts, Folium Artemisiae Argyi 20 parts, Flos Lonicerae 18 parts, bamboo powder 15 parts, 12 parts, mustard, Borneolum Syntheticum 5 parts, Calyx Seu Fructus Physalis 5 parts, distilled water 900 parts.
The present embodiment external bactericidal antiphlogistic ointment preparation method processing step and usage and dosage identical with embodiment 1.
Using method: after clean of morning and evening every day, be coated with ointment 1-3 millimeters thick of the present invention; Meanwhile, maror is eaten less in diet aspect, absorbs water fruit vegetable more, drinks water more.
Model case:
1, Zhang, man, 23 years old, the new village people in Henan, face suffers from serious acne, and inflammation causes redness, have burning sensation, period has used multiple way, does not improve after smearing medicine, used external bactericidal antiphlogistic ointment of the present invention afterwards, after using one week, the burning sensation of face disappears, red and swollen disappearance, continue to use rear skin to flatten, face is repaired normal.
2, Wu, female, 35 years old, people from Wuhan, Hubei, summer, arm was scraped off because of carelessness, owing to not paying attention to, wound suppuration infects, and introduces, after using externally applied anti-inflammation ointment of the present invention through friend, treatment has had obvious effect, and inflammation disappears, and after incrustation, dead bark comes off naturally, does not have cicatrix.
3, Wei, female, 17 years old, people from Changsha, overgrowed with comedo on the face, skin slices are rubescent, cause feeling oneself inferior a little, have a strong impact on school work, and school grade also starts to glide, use externally applied anti-inflammation ointment of the present invention after one week, the redness of face obviously weakens, and after continuing use, skin recovers normal.
The above; be only the specific embodiment of the present invention, but protection scope of the present invention is not limited thereto, is anyly familiar with those skilled in the art in the technical scope that the present invention discloses; change can be expected easily or replace, all should be encompassed within protection scope of the present invention.Therefore, protection scope of the present invention should be as the criterion with the protection domain of described claim.

Claims (3)

1. an external bactericidal antiphlogistic ointment, is characterized in that, is formed by the preparation of raw material of following weight portion: anion powder 20-40 part, nano silicon 10-20 part, nano magnesia 2-8 part, bamboo charcoal nano 1-5 part, Folium Artemisiae Argyi 10-20 part, Flos Lonicerae 5-20 part, bamboo powder 5-15 part, mustard 5-12 part, Borneolum Syntheticum 1-5 part, Calyx Seu Fructus Physalis 1-5 part, distilled water 600-900 part.
2. external bactericidal antiphlogistic ointment according to claim 1, is characterized in that, formed by the preparation of raw material of following weight portion: anion powder 30 parts, nano silicon 16 parts, nano magnesia 5 parts, bamboo charcoal nano 2 parts, Folium Artemisiae Argyi 13 parts, Flos Lonicerae 10 parts, bamboo powder 10 parts, 7 parts, mustard, Borneolum Syntheticum 3 parts, Calyx Seu Fructus Physalis 2 parts, distilled water 800 parts.
3. prepare external bactericidal antiphlogistic ointment according to claim 1, it is characterized in that, comprise the following steps:
(1) raw material is got according to weight fraction another name;
(2) by Flos Lonicerae, mustard, Borneolum Syntheticum, Calyx Seu Fructus Physalis is pulverized for subsequent use;
(3) by Folium Artemisiae Argyi, Flos Lonicerae, bamboo powder, mustard, Borneolum Syntheticum, Calyx Seu Fructus Physalis puts into container, adds distilled water, at room temperature soaks after 2-3 hour, boils 1.5-3 hour, filter in time being down to room temperature with gauze, obtain filtrate and filtering residue under 100 C, for subsequent use;
(4) by anion powder, nano silicon, nano magnesia, bamboo charcoal nano joins in the filtering residue described in step (3), and after stirring, be 120 C in temperature, sterilize under the condition of 2 normal atmospheres 20min, obtains aseptic thick paste;
(5) filtrate described in step (3) is distilled under temperature is 100 C, obtain distillate, after to be distilled, in distillate, continue to pass into ozone 10min sterilize, obtain aseptic distillate;
(6) by the aseptic thick paste described in step (4) and the described aseptic distillate mixing of step (5), stir into paste, obtain external bactericidal antiphlogistic ointment of the present invention.
CN201610000845.XA 2016-01-04 2016-01-04 External sterilization antipyrotic cream and preparation method thereof Pending CN105535605A (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1586541A (en) * 2004-07-06 2005-03-02 王力 External use medicine for preventing respiratory infectious disease and its preparing method
CN103416435A (en) * 2013-03-20 2013-12-04 俞锃 Medicinal mould inhibitor and preparation method thereof
CN103585268A (en) * 2013-11-29 2014-02-19 罗泽良 Acne-treating composition and preparation method thereof, and acne-treating skin-care product
CN103937391A (en) * 2014-03-21 2014-07-23 安徽蓝柯复合材料有限公司 Antibacterial self-dry paint and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1586541A (en) * 2004-07-06 2005-03-02 王力 External use medicine for preventing respiratory infectious disease and its preparing method
CN103416435A (en) * 2013-03-20 2013-12-04 俞锃 Medicinal mould inhibitor and preparation method thereof
CN103585268A (en) * 2013-11-29 2014-02-19 罗泽良 Acne-treating composition and preparation method thereof, and acne-treating skin-care product
CN103937391A (en) * 2014-03-21 2014-07-23 安徽蓝柯复合材料有限公司 Antibacterial self-dry paint and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
李娟等: "中药抗菌作用的研究进展", 《中国药业》 *

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