CN105535605A - External sterilization antipyrotic cream and preparation method thereof - Google Patents
External sterilization antipyrotic cream and preparation method thereof Download PDFInfo
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- CN105535605A CN105535605A CN201610000845.XA CN201610000845A CN105535605A CN 105535605 A CN105535605 A CN 105535605A CN 201610000845 A CN201610000845 A CN 201610000845A CN 105535605 A CN105535605 A CN 105535605A
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- 238000002360 preparation method Methods 0.000 title claims description 20
- 230000001954 sterilising effect Effects 0.000 title abstract description 6
- 238000004659 sterilization and disinfection Methods 0.000 title abstract 5
- 239000006071 cream Substances 0.000 title abstract 4
- CPLXHLVBOLITMK-UHFFFAOYSA-N Magnesium oxide Chemical compound [Mg]=O CPLXHLVBOLITMK-UHFFFAOYSA-N 0.000 claims abstract description 32
- 239000000843 powder Substances 0.000 claims abstract description 31
- 235000017166 Bambusa arundinacea Nutrition 0.000 claims abstract description 30
- 235000017491 Bambusa tulda Nutrition 0.000 claims abstract description 30
- 241001330002 Bambuseae Species 0.000 claims abstract description 30
- 235000015334 Phyllostachys viridis Nutrition 0.000 claims abstract description 30
- 239000011425 bamboo Substances 0.000 claims abstract description 30
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 18
- 235000003351 Brassica cretica Nutrition 0.000 claims abstract description 18
- 235000003343 Brassica rupestris Nutrition 0.000 claims abstract description 18
- QKSKPIVNLNLAAV-UHFFFAOYSA-N bis(2-chloroethyl) sulfide Chemical compound ClCCSCCCl QKSKPIVNLNLAAV-UHFFFAOYSA-N 0.000 claims abstract description 18
- 235000010460 mustard Nutrition 0.000 claims abstract description 18
- 239000000395 magnesium oxide Substances 0.000 claims abstract description 16
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 16
- 239000003610 charcoal Substances 0.000 claims abstract description 15
- 239000005543 nano-size silicon particle Substances 0.000 claims abstract description 15
- 239000012153 distilled water Substances 0.000 claims abstract description 14
- 230000000844 anti-bacterial effect Effects 0.000 claims description 34
- 239000002674 ointment Substances 0.000 claims description 28
- 239000002260 anti-inflammatory agent Substances 0.000 claims description 27
- 230000001741 anti-phlogistic effect Effects 0.000 claims description 27
- 241000628997 Flos Species 0.000 claims description 18
- 241000219198 Brassica Species 0.000 claims description 17
- 241001164374 Calyx Species 0.000 claims description 17
- 244000064622 Physalis edulis Species 0.000 claims description 17
- 150000001450 anions Chemical class 0.000 claims description 15
- 239000002994 raw material Substances 0.000 claims description 12
- 239000000706 filtrate Substances 0.000 claims description 6
- 238000001914 filtration Methods 0.000 claims description 6
- 238000003756 stirring Methods 0.000 claims description 6
- CBENFWSGALASAD-UHFFFAOYSA-N Ozone Chemical compound [O-][O+]=O CBENFWSGALASAD-UHFFFAOYSA-N 0.000 claims description 3
- 238000002156 mixing Methods 0.000 claims description 3
- 230000000694 effects Effects 0.000 abstract description 14
- 206010061218 Inflammation Diseases 0.000 abstract description 9
- 230000004054 inflammatory process Effects 0.000 abstract description 7
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- 230000007803 itching Effects 0.000 abstract description 2
- 239000000463 material Substances 0.000 abstract description 2
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 abstract 1
- 241000205585 Aquilegia canadensis Species 0.000 abstract 1
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- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 abstract 1
- 230000003467 diminishing effect Effects 0.000 abstract 1
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 abstract 1
- 230000002884 effect on inflammation Effects 0.000 abstract 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N silicon dioxide Inorganic materials O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
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- 230000003266 anti-allergic effect Effects 0.000 description 1
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- 239000002221 antipyretic Substances 0.000 description 1
- 230000000721 bacterilogical effect Effects 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 229940095731 candida albicans Drugs 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
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- 230000002354 daily effect Effects 0.000 description 1
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- 238000010792 warming Methods 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/08—Oxides; Hydroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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Abstract
The invention relates to an external sterilization antipyrotic cream. The external sterilization antipyrotic cream is prepared from, by weight, 20-40 parts of negative ion powder, 10-20 parts of nano-silicon dioxide, 2-8 parts of nanometer magnesia, 1-5 parts of nanometer bamboo charcoal, 10-20 parts of moxa, 5-20 parts of honeysuckle, 5-15 parts of bamboo powder, 5-12 parts of mustard, 1-5 parts of borneol, 1-5 parts of Physalis alkekengi and 600-900 parts of distilled water. Due to the adopted pure plants, the external sterilization antipyrotic cream is free of side effects, has the effects of achieving sterilization, diminishing inflammation, clearing away heat and toxic materials, dispelling moisture and relieving itching, and particularly has the remarkable curative effect on inflammations caused by staphylococcus, escherichia coli and the like.
Description
Technical field
The present invention relates to technical field of Chinese medicines, particularly a kind of external bactericidal antiphlogistic ointment and preparation method thereof.
Background technology
Acne is apt to occur in face and back, blocks that the bacteriological infection that causes and inflammation cause primarily of hypersteatosis, hair follicle, to the psychology of people with socially cause very large impact.Severe patient relies on Drug therapy, but containing a large amount of antibiotic and hormone in conventional medicine, life-time service can cause dependence and side effect.
For the dermatitis that the dermatosis of other classes causes as skin scald, burn, often see in daily life, as incorrect medication, skin histology can be made impaired, bring the burden on spiritual pressure and material to patient.
Summary of the invention
For solving the problem, the invention provides a kind of external bactericidal antiphlogistic ointment, external bactericidal antiphlogistic ointment of the present invention adopts pure natural medical, has no side effect, bactericidal anti-inflammatory effect is remarkable, and the inflammation especially caused staphylococcus and escherichia coli etc. has significant curative effect.
For achieving the above object, the present invention is achieved through the following technical solutions:
The present invention is formed by the preparation of raw material of following weight portion: anion powder 20-40 part, nano silicon 10-20 part, nano magnesia 2-8 part, bamboo charcoal nano 1-5 part, Folium Artemisiae Argyi 10-20 part, Flos Lonicerae 5-20 part, bamboo powder 5-15 part, mustard 5-12 part, Borneolum Syntheticum 1-5 part, Calyx Seu Fructus Physalis 1-5 part, distilled water 600-900 part.
The preferred technical solution of the present invention is: anion powder 30 parts, nano silicon 16 parts, nano magnesia 5 parts, bamboo charcoal nano 2 parts, Folium Artemisiae Argyi 13 parts, Flos Lonicerae 10 parts, bamboo powder 10 parts, 7 parts, mustard, Borneolum Syntheticum 3 parts, Calyx Seu Fructus Physalis 2 parts, distilled water 800 parts.
Prepare above-mentioned external bactericidal antiphlogistic ointment, comprise the following steps:
(1) raw material is got according to weight fraction another name;
(2) by Flos Lonicerae, mustard, Borneolum Syntheticum, Calyx Seu Fructus Physalis is pulverized for subsequent use;
(3) by Folium Artemisiae Argyi, Flos Lonicerae, bamboo powder, mustard, Borneolum Syntheticum, Calyx Seu Fructus Physalis puts into container, adds distilled water, at room temperature soaks after 2-3 hour, boils 1.5-3 hour, filter in time being down to room temperature with gauze, obtain filtrate and filtering residue under 100 C, for subsequent use;
(4) by anion powder, nano silicon, nano magnesia, bamboo charcoal nano joins in the filtering residue described in step (3), and after stirring, be 120 C in temperature, sterilize under the condition of 2 normal atmospheres 20min, obtains aseptic thick paste;
(5) filtrate described in step (3) is distilled under temperature is 100 C, obtain distillate, after to be distilled, in distillate, continue to pass into ozone 10min sterilize, obtain aseptic distillate;
(6) by the aseptic thick paste described in step (4) and the described aseptic distillate mixing of step (5), stir into paste, obtain external bactericidal antiphlogistic ointment of the present invention.
Described weight portion can be g, kg according to the needs of preparation, two, and the measurement units such as jin.Same measurement unit can only be used in same embodiment.
In external-applied ointment of the present invention, anion powder has higher activity, has very strong redox, can destroy the cell membrane of antibacterial or the activity of cellular plasm organized enzyme, reach the object of antibiotic and sterilizing.Meanwhile, anion powder can stimulate Cucumber Extract, reaches treatment comedo, the dermatosiss such as exedens dermatitis.
Nano silicon has physiological inertia, high adsorption, in the preparation of antibacterial, be commonly used for carrier, and when being used as carrier, adsorbable antibacterial ion, reaches the object of bactericidal antiphlogistic.
Nano magnesia has oxidisability and the Electrostatic Absorption to microorganism, utilizes these character can reach the object of bactericidal antiphlogistic.Nano magnesia especially has significant killing effect to escherichia coli, staphylococcus aureus and bacillus subtilis etc.
Summer-heat, antipyretic, removing toxic substances, can fall in Calyx Seu Fructus Physalis.
Folium Artemisiae Argyi, warming the meridian for stopping bleeding, antiinflammatory, antiallergic.
Flos Lonicerae, has heat-clearing and toxic substances removing, effect of antiinflammatory.Experiment in vitro shows, Flos Lonicerae as staphylococcus aureus, Hemolytic streptococcus, escherichia coli have significant inhibitory action, also has certain effect to other antibacterial such as tubercule bacillus to various pathogens.
Bamboo powder and mustard have the effect of heat-clearing and toxic substances removing.
Borneolum Syntheticum, have the loose poison of heat clearing away, effect of improving acuity of vision and removing nebula, can accelerate the elimination of inflammation, and promote stripping off of mucosa, the healing of ulcer, to the mucosal injury that antibacterial is caused, can play the effect of auxiliary treatment.
Bamboo charcoal nano, has very strong absorbability, has to antibacterial such as staphylococcus, escherichia coli, the Candida albicans of absorption the inhibitory action that well sterilizes.
Compared with prior art, the pure plant that the present invention adopts, have no side effect, have effect of bactericidal antiphlogistic, heat-clearing and toxic substances removing, removing dampness to relieve itching, the inflammation especially caused staphylococcus and escherichia coli etc. has significant curative effect.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described in further detail.
Embodiment 1: a kind of external bactericidal antiphlogistic ointment, formed by the preparation of raw material of following weight portion: anion powder 20 parts, nano silicon 10 parts, nano magnesia 2 parts, bamboo charcoal nano 1 part, Folium Artemisiae Argyi 10 parts, Flos Lonicerae 5 parts, bamboo powder 5 parts, 5 parts, mustard, Borneolum Syntheticum 1 part, Calyx Seu Fructus Physalis 1 part, distilled water 600 parts.
External bactericidal antiphlogistic ointment described in preparation, comprises the following steps:
(1) raw material is got according to weight fraction another name;
(2) by Flos Lonicerae, mustard, Borneolum Syntheticum, Calyx Seu Fructus Physalis is pulverized for subsequent use;
(3) by Folium Artemisiae Argyi, Flos Lonicerae, bamboo powder, mustard, Borneolum Syntheticum, Calyx Seu Fructus Physalis puts into container, adds distilled water, at room temperature soaks after 2-3 hour, boils 1.5-3 hour, filter in time being down to room temperature with gauze, obtain filtrate and filtering residue under 100 C, for subsequent use;
(4) by anion powder, nano silicon, nano magnesia, bamboo charcoal nano joins in the filtering residue described in step (3), and after stirring, be 120 C in temperature, sterilize under the condition of 2 normal atmospheres 20min, obtains aseptic thick paste;
(5) filtrate described in step (3) is distilled under temperature is 100 C, obtain distillate, after to be distilled, in distillate, continue to pass into ozone 10min sterilize, obtain aseptic distillate;
(6) by the aseptic thick paste described in step (4) and the described aseptic distillate mixing of step (5), stir into paste, obtain external bactericidal antiphlogistic ointment of the present invention.
Embodiment 2: a kind of external bactericidal antiphlogistic ointment, formed by the preparation of raw material of following weight portion: anion powder 25 parts, nano silicon 12 parts, nano magnesia 4 parts, bamboo charcoal nano 2 parts, Folium Artemisiae Argyi 12 parts, Flos Lonicerae 7 parts, bamboo powder 8 parts, 6 parts, mustard, Borneolum Syntheticum 2 parts, Calyx Seu Fructus Physalis 2 parts, distilled water 700 parts.
The present embodiment external bactericidal antiphlogistic ointment preparation method processing step and usage and dosage identical with embodiment 1.
Embodiment 3: a kind of external bactericidal antiphlogistic ointment, formed by the preparation of raw material of following weight portion: anion powder 30 parts, nano silicon 16 parts, nano magnesia 5 parts, bamboo charcoal nano 2 parts, Folium Artemisiae Argyi 13 parts, Flos Lonicerae 10 parts, bamboo powder 10 parts, 7 parts, mustard, Borneolum Syntheticum 3 parts, Calyx Seu Fructus Physalis 2 parts, distilled water 800 parts.
The present embodiment external bactericidal antiphlogistic ointment preparation method processing step and usage and dosage identical with embodiment 1.
Embodiment 4: a kind of external bactericidal antiphlogistic ointment, formed by the preparation of raw material of following weight portion: anion powder 33 parts, nano silicon 17 parts, nano magnesia 6 parts, bamboo charcoal nano 3 parts, Folium Artemisiae Argyi 15 parts, Flos Lonicerae 13 parts, bamboo powder 11 parts, 9 parts, mustard, Borneolum Syntheticum 3 parts, Calyx Seu Fructus Physalis 3 parts, distilled water 850 parts.
The present embodiment external bactericidal antiphlogistic ointment preparation method processing step and usage and dosage identical with embodiment 1.
Embodiment 5: a kind of external bactericidal antiphlogistic ointment, formed by the preparation of raw material of following weight portion: anion powder 35 parts, nano silicon 18 parts, nano magnesia 7 parts, bamboo charcoal nano 4 parts, Folium Artemisiae Argyi 16 parts, Flos Lonicerae 16 parts, bamboo powder 13 parts, 10 parts, mustard, Borneolum Syntheticum 4 parts, Calyx Seu Fructus Physalis 4 parts, distilled water 880 parts.
The present embodiment external bactericidal antiphlogistic ointment preparation method processing step and usage and dosage identical with embodiment 1.
Embodiment 6: a kind of external bactericidal antiphlogistic ointment, formed by the preparation of raw material of following weight portion: anion powder 40 parts, nano silicon 20 parts, nano magnesia 8 parts, bamboo charcoal nano 5 parts, Folium Artemisiae Argyi 20 parts, Flos Lonicerae 18 parts, bamboo powder 15 parts, 12 parts, mustard, Borneolum Syntheticum 5 parts, Calyx Seu Fructus Physalis 5 parts, distilled water 900 parts.
The present embodiment external bactericidal antiphlogistic ointment preparation method processing step and usage and dosage identical with embodiment 1.
Using method: after clean of morning and evening every day, be coated with ointment 1-3 millimeters thick of the present invention; Meanwhile, maror is eaten less in diet aspect, absorbs water fruit vegetable more, drinks water more.
Model case:
1, Zhang, man, 23 years old, the new village people in Henan, face suffers from serious acne, and inflammation causes redness, have burning sensation, period has used multiple way, does not improve after smearing medicine, used external bactericidal antiphlogistic ointment of the present invention afterwards, after using one week, the burning sensation of face disappears, red and swollen disappearance, continue to use rear skin to flatten, face is repaired normal.
2, Wu, female, 35 years old, people from Wuhan, Hubei, summer, arm was scraped off because of carelessness, owing to not paying attention to, wound suppuration infects, and introduces, after using externally applied anti-inflammation ointment of the present invention through friend, treatment has had obvious effect, and inflammation disappears, and after incrustation, dead bark comes off naturally, does not have cicatrix.
3, Wei, female, 17 years old, people from Changsha, overgrowed with comedo on the face, skin slices are rubescent, cause feeling oneself inferior a little, have a strong impact on school work, and school grade also starts to glide, use externally applied anti-inflammation ointment of the present invention after one week, the redness of face obviously weakens, and after continuing use, skin recovers normal.
The above; be only the specific embodiment of the present invention, but protection scope of the present invention is not limited thereto, is anyly familiar with those skilled in the art in the technical scope that the present invention discloses; change can be expected easily or replace, all should be encompassed within protection scope of the present invention.Therefore, protection scope of the present invention should be as the criterion with the protection domain of described claim.
Claims (3)
1. an external bactericidal antiphlogistic ointment, is characterized in that, is formed by the preparation of raw material of following weight portion: anion powder 20-40 part, nano silicon 10-20 part, nano magnesia 2-8 part, bamboo charcoal nano 1-5 part, Folium Artemisiae Argyi 10-20 part, Flos Lonicerae 5-20 part, bamboo powder 5-15 part, mustard 5-12 part, Borneolum Syntheticum 1-5 part, Calyx Seu Fructus Physalis 1-5 part, distilled water 600-900 part.
2. external bactericidal antiphlogistic ointment according to claim 1, is characterized in that, formed by the preparation of raw material of following weight portion: anion powder 30 parts, nano silicon 16 parts, nano magnesia 5 parts, bamboo charcoal nano 2 parts, Folium Artemisiae Argyi 13 parts, Flos Lonicerae 10 parts, bamboo powder 10 parts, 7 parts, mustard, Borneolum Syntheticum 3 parts, Calyx Seu Fructus Physalis 2 parts, distilled water 800 parts.
3. prepare external bactericidal antiphlogistic ointment according to claim 1, it is characterized in that, comprise the following steps:
(1) raw material is got according to weight fraction another name;
(2) by Flos Lonicerae, mustard, Borneolum Syntheticum, Calyx Seu Fructus Physalis is pulverized for subsequent use;
(3) by Folium Artemisiae Argyi, Flos Lonicerae, bamboo powder, mustard, Borneolum Syntheticum, Calyx Seu Fructus Physalis puts into container, adds distilled water, at room temperature soaks after 2-3 hour, boils 1.5-3 hour, filter in time being down to room temperature with gauze, obtain filtrate and filtering residue under 100 C, for subsequent use;
(4) by anion powder, nano silicon, nano magnesia, bamboo charcoal nano joins in the filtering residue described in step (3), and after stirring, be 120 C in temperature, sterilize under the condition of 2 normal atmospheres 20min, obtains aseptic thick paste;
(5) filtrate described in step (3) is distilled under temperature is 100 C, obtain distillate, after to be distilled, in distillate, continue to pass into ozone 10min sterilize, obtain aseptic distillate;
(6) by the aseptic thick paste described in step (4) and the described aseptic distillate mixing of step (5), stir into paste, obtain external bactericidal antiphlogistic ointment of the present invention.
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CN116159176A (en) * | 2023-02-15 | 2023-05-26 | 南通大学 | Hemostatic bandage and preparation method thereof |
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