CN105535446A - Medicine for treating myocardial infarction - Google Patents

Medicine for treating myocardial infarction Download PDF

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Publication number
CN105535446A
CN105535446A CN201610105463.3A CN201610105463A CN105535446A CN 105535446 A CN105535446 A CN 105535446A CN 201610105463 A CN201610105463 A CN 201610105463A CN 105535446 A CN105535446 A CN 105535446A
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radix
medicine
myocardial infarction
blood
effect
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武步旭
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537—Salvia (sage)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236—Ligusticum (licorice-root)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/42—Cucurbitaceae (Cucumber family)
    • A61K36/428—Trichosanthes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8962—Allium, e.g. garden onion, leek, garlic or chives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968—Ophiopogon (Lilyturf)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention provides a medicine for treating myocardial infarction and belongs to the field of traditional Chinese medicines. The medicine is prepared from 30 g of salvia miltiorrhiza, 25 g of allium macrostemon, 25 g of full fructus trichosanthis, 25 g of radix ophiopogonis, 20 g of Szechwan lovage rhizomes, 20 g of pseudo-ginsengs, 20 g of radix cyathulae, 5 g of borneol and 3 g of licorice roots. 66 treatment cases prove that the effective rate of the medicine used for treating the myocardial infarction is 95%.

Description

A kind of Chinese medicine for the treatment of myocardial infarction
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind of Chinese medicine for the treatment of myocardial infarction.
Background technology
Acute myocardial infarction refers to coronary artery acute occlusion, blood flow ceases, caused regional myocardial ischemic necrosis, clinical manifestation can have lasting retrosternal pain, shock, arrhythmia and heart failure, and has Serum fibrosis markers to increase and Electrocardiographic change.Can complicated by arrhythmia, shock or heart failure, often can threat to life.China's acute myocardial infarction is in recent years obvious ascendant trend, newly sends to few 500,000 every year, existing trouble at least 200 ten thousand.
Summary of the invention
In order to alleviate the untoward reaction of patient, the present invention proposes safe and efficient a kind of Chinese medicine for the treatment of myocardial infarction.
Treat a Chinese medicine for myocardial infarction, it is characterized in that material composition is: Radix Salviae Miltiorrhizae 30g, Bulbus Allii Macrostemonis 25g, Fructus Trichosanthis 25g, Radix Ophiopogonis 25g, Rhizoma Chuanxiong 20g, Radix Notoginseng 20g, Radix Cyathulae 20g, Borneolum Syntheticum 5g, Radix Glycyrrhizae 3g.
91 mesh sieves are crossed by after above-mentioned raw materials co-grinding.
Radix Salviae Miltiorrhizae is monarch drug; Bulbus Allii Macrostemonis, Fructus Trichosanthis, Radix Ophiopogonis are ministerial drug; Rhizoma Chuanxiong, Radix Notoginseng, Radix Cyathulae are adjuvant drug; Borneolum Syntheticum, Radix Glycyrrhizae are for making medicine.
Radix Salviae Miltiorrhizae: nature and flavor are bitter, cold.Enter heart channel, pericardium channel, Liver Channel.
Effect of Radix Salviae Miltiorrhizae: promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, relieving restlessness is calmed the nerves.
Modern medicine study proves: Radix Salviae Miltiorrhizae has blood pressure lowering, improves microcirculation, coronary artery dilating; increase coronary flow, improve myocardial ischemia, anoxia, promote the recovery for the treatment of myocardial ischemia damage; reduce the scope of myocardial infarction, improve hypoxia-bearing capability, protection is play a part to hypoxic cardiac muscle.
Bulbus Allii Macrostemonis: nature and flavor are pungent, bitter, temperature.Enter lung meridian, stomach warp, large intestine channel.
Effect of Bulbus Allii Macrostemonis: activating YANG and eliminating stagnation, circulation of qi promoting intestinal stasis relieving.
Bulbus Allii Macrostemonis effect: pungent loose, hardship is fallen, Wen Tong, slides profit, kind loose YIN-cold is to stagnate, and what lead to breast sun closes knot, for controlling the thoracic obstruction, the expectorant stasis of blood, key medicine uncomfortable in chest;
Modern medicine study proves: Bulbus Allii Macrostemonis obviously can reduce Serum LPO Levels, anti-platelet aggregation, and reduce lipid plaque, prevention of arterial is atherosis, has protective effect, have inhibition to streptococcus pneumoniae to myocardial ischemia, ischemia.
" Medical Treasures of the Golden Chamber " is recorded: Bulbus Allii Macrostemonis, Fructus Trichosanthis, Chinese liquor are decocted soup clothes and controlled the thoracic obstruction, chest pain.
Fructus Trichosanthis: property mildly bitter flavor, cold.Enter stomach warp, large intestine channel, lung meridian.
Effect of Fructus Trichosanthis: removing heat-phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, loosening bowel to relieve constipation.
Be used for the treatment of cough due to lung-heat, the turbid Huang of expectorant is thick, obstruction of qi in the chest and cardialgia, blocked-up chest feeling of fullness, acute mastitis, lung abscess, and acute appendicitis swells and ache, constipation.
Modern medicine study proves: Fructus Trichosanthis can blood fat reducing, antibacterial, has inhibitory action, have significant protective effect to myocardial ischemia to Diplococcus pneumoniae, bacillus pyocyaneus, Hemolytic streptococcus and hemophilus influenza.
Radix Ophiopogonis, nature and flavor were sweet, and micro-hardship, is slightly cold.Enter stomach warp, heart channel, lung meridian.
There is Radix Ophiopogonis effect of nourishing YIN and moistening the lung, reinforcing stomach reg fluid, the relieving restlessness that clears away heart-fire.
Modern pharmacological research also shows: Radix Ophiopogonis containing dwarf lilyturf glycosides, steroidal saponin, alkaloid, sitosterol, glucose, aminoacid, vitamin, has resisting fatigue, scavenging free radicals, raising cellular immune function, increases interrenal system, strengthens coronary flow, blood sugar lowering, calmness, hypnosis, resists myocardial ischemia, arrhythmia, antineoplastic action.Especially improve left ventricular function to recover.
Rhizoma Chuanxiong: nature and flavor are pungent, temperature.Enter Liver Channel, gallbladder meridian, pericardium channel.
Effect of Rhizoma Chuanxiong: blood-activating and qi-promoting, wind-expelling pain-stopping.For treatment blood stasis, the stagnation of QI, the key medicine of pain relieving;
Modern medicine study proves: Rhizoma Chuanxiong has coronary artery dilating, increase coronary flow, improve myocardium blood oxygen under-supply, reduce myocardial oxygen consumption, expansion of cerebral vascular, reduce vascular resistance, increase brain and LBF amount, improve microcirculation, suppress platelet aggregation, antithrombotic, calm, the effect of blood pressure lowering
Radix Notoginseng is also known as Radix Notoginseng.
Radix Notoginseng nature and flavor are sweet, micro-hardship, temperature.Enter Liver Channel, stomach warp.Removing stasis to stop bleeding, analgesic therapy of invigorating blood circulation.
Modern medicine study proves: the kind hemostasis of Radix Notoginseng, again can blood stasis dispersing and fresh blood promoting, and have hemostasis not stay the stasis of blood, positive feature is not hindered in blood stasis dispelling;
Radix Notoginseng can shorten the bleeding time, shortens clotting time; There is the effect of anti-platelet aggregation, multi-functional hemopoietic can be promoted, blood pressure lowering, decreased heart rate, expansion of cerebral vascular, increase cerebrovascular flow, improve body's immunity; There is analgesic and anti-inflammatory effects.
Radix Cyathulae: nature and flavor are bitter, sweet, acid is flat.Enter Liver Channel, kidney channel.
Effect of Radix Cyathulae: promoting blood circulation to restore menstrual flow, invigorating the liver and kidney, bone and muscle strengthening, relieving stranguria by diuresis, blood of igniting is descending.
Modern medicine study proves: Radix Cyathulae has blood fat reducing, blood pressure lowering, antiinflammatory, analgesia, improves effect of body's immunity.
Borneolum Syntheticum: nature and flavor are pungent, bitter, be slightly cold.Enter heart channel, spleen channel, lung meridian.
Effect of Borneolum Syntheticum: refreshment of having one's ideas straightened out, clearing away heat to alleviate pain.
Modern medicine study proves: Borneolum Syntheticum has inhibition to staphylococcus, streptococcus, streptococcus pneumoniae, escherichia coli.
Radix Glycyrrhizae nature and flavor are sweet flat.Enter spleen channel, heart channel, lung meridian, kidney channel.
Radix Glycyrrhizae has invigorating the spleen and replenishing QI, expelling phlegm for arresting cough, heat-clearing and toxic substances removing, relieving spasm to stop pain, effect of mediation drug storage.
Radix Glycyrrhizae is treatment deficiency of heart-QI, irregularly intermittent and regularly intermittent pulse, the good medicine of severe palpitation, energy reinforce functional activities of the heart, Yiqi and vein recovery.
Modern medicine study proves: Radix Glycyrrhizae has antiarrhythmic effect.
Through the checkings of 66 example treatment cases, the present invention has blood circulation promoting and blood stasis dispelling, activating YANG and eliminating stagnation, inducing menstruation to relieve menalgia, dispels the effect of the stasis blocking caused because of wind, cold, wet, expectorant.The effective percentage that the present invention is used for the treatment for the treatment of myocardial infarction is 95%, and adverse reactions of patients is little.
Detailed description of the invention
Treat a Chinese medicine for myocardial infarction, it is characterized in that material composition is: Radix Salviae Miltiorrhizae 30g, Bulbus Allii Macrostemonis 25g, Fructus Trichosanthis 25g, Radix Ophiopogonis 25g, Rhizoma Chuanxiong 20g, Radix Notoginseng 20g, Radix Cyathulae 20g, Borneolum Syntheticum 5g, Radix Glycyrrhizae 3g.
Crossing 91 mesh sieves after being pulverized by above-mentioned raw materials mix homogeneously, is a collation package by every 10g.Patient per (medicine) being taken before meal 10g half an hour ante cibum, boiled water is taken after mixing it with water, and takes 3 every day.
Treatment case:
Patient: male, 46 years old, examination in hospital was reported as: the nearly section of left anterior descending branch narrow about 30%, stage casing narrow about 85%, Circumflex branch stage casing narrow about 30%, right coronary artery stage casing narrow about 30%.Blood pressure is 150/90mmHg.
Patient takes every day of the present invention 3 times, and boiled water is taken after mixing it with water, each half an hour ante cibum (medicine) being taken before meal 10g, take 6 months altogether, the nearly section of left anterior descending branch narrow about 10% of patient, stage casing narrow about 30%, Circumflex branch stage casing narrow about 10%, right coronary artery stage casing narrow about 10%, blood pressure is 130/80mmHg.

Claims (1)

1. treat a Chinese medicine for myocardial infarction, it is characterized in that material composition is: Radix Salviae Miltiorrhizae 30g, Bulbus Allii Macrostemonis 25g, Fructus Trichosanthis 25g, Radix Ophiopogonis 25g, Rhizoma Chuanxiong 20g, Radix Notoginseng 20g, Radix Cyathulae 20g, Borneolum Syntheticum 5g, Radix Glycyrrhizae 3g.
CN201610105463.3A 2016-02-26 2016-02-26 Medicine for treating myocardial infarction Pending CN105535446A (en)

Priority Applications (1)

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CN201610105463.3A CN105535446A (en) 2016-02-26 2016-02-26 Medicine for treating myocardial infarction

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610105463.3A CN105535446A (en) 2016-02-26 2016-02-26 Medicine for treating myocardial infarction

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102058757A (en) * 2010-11-25 2011-05-18 代龙 Traditional Chinese medicinal composition for treating cardiovascular diseases and preparation method thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102058757A (en) * 2010-11-25 2011-05-18 代龙 Traditional Chinese medicinal composition for treating cardiovascular diseases and preparation method thereof

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
李殊响: "《百病对药对穴疗法》", 31 December 2013, 人民军医出版社 *
翁维良等: "《临床中药学》", 31 May 1998, 河南科学技术出版社 *
郇宜俊等: "《家庭实用中成药》", 31 January 2000, 人民卫生出版社 *
钟相根: "《张仲景传世名方.金匮要略卷》", 28 February 2013, 中国医药科技出版社 *

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Application publication date: 20160504

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